Istituto di Ricerche Farmacologiche "Mario Negri"

Research Output

2020

Accelerating the Depletion of Circulating Anti-Phospholipase A2 Receptor Antibodies in Patients with Severe Membranous Nephropathy: Preliminary Findings with Double Filtration Plasmapheresis and Ofatumumab

Podestà, M. A., Gennarini, A., Portalupi, V., Rota, S., Alessio, M. G., Remuzzi, G. & Ruggenenti, P., 2020, In : Nephron. 144, 1, p. 30-35 6 p.

Research output: Contribution to journalArticle

Analysis of BRCA1 and RAD51C promoter methylation in italian families at high-risk of breast and ovarian cancer

Tabano, S., Azzollini, J., Pesenti, C., Lovati, S., Costanza, J., Fontana, L., Peissel, B., Miozzo, M. & Manoukian, S., Apr 2020, In : Cancers. 12, 4, 910.

Research output: Contribution to journalArticle

Open Access

Assessment of Duration and Effects of 3 vs 6 Months of Adjuvant Chemotherapy in High-Risk Stage II Colorectal Cancer: A Subgroup Analysis of the TOSCA Randomized Clinical Trial

Petrelli, F., Labianca, R., Zaniboni, A., Lonardi, S., Galli, F., Rulli, E., Rosati, G., Corallo, S., Ronzoni, M., Cardellino, G. G., Mattioli, R., Mambrini, A., Ciuffreda, L., Banzi, M., Pusceddu, V., Maiello, E., Zampino, M., Zagonel, V., Marchetti, P., Corsi, D. & 3 others, Rimassa, L., Cinieri, S. & Sobrero, A., Apr 2020, In : JAMA oncology. 6, 4, p. 547-551 5 p.

Research output: Contribution to journalArticle

Atopic dermatitis phenotypes in preschool and school-age children: A latent class analysis

Panel of the Italian Society of Pediatric Allergy Immunology (SIAIP, Jan 1 2020, In : Journal of Investigational Allergology and Clinical Immunology. 30, 2, p. 108-116 9 p.

Research output: Contribution to journalArticle

Open Access
Open Access
Open Access

A validation study of the clinical diagnosis of Dup15q syndrome: Which symptoms matter most?

Beghi, E., Giussani, G., Bianchi, E., Randazzo, G., Sarcona, V., Elia, M., Striano, P., Verrotti, A., Ferretti, A., Rebessi, E., Specchio, N. & Bonanni, P., Jan 2020, In : Seizure. 74, p. 26-30 5 p.

Research output: Contribution to journalArticle

Carbon monoxide (CO) and nitric dioxide (NO2) exposure during fetal life: impact on neonatal and placental weight, a prospective study

Giovannini, N., Cetera, G. E., Signorelli, V., Parazzini, F., Baini, I., Cipriani, S. & Cetin, I., Jul 2 2020, In : Journal of Maternal-Fetal and Neonatal Medicine. 33, 13, p. 2137-2141 5 p.

Research output: Contribution to journalArticle

Correction to: A nonsynonymous mutation in PLCG2 reduces the risk of Alzheimer’s disease, dementia with Lewy bodies and frontotemporal dementia, and increases the likelihood of longevity (Acta Neuropathologica, (2019), 138, 2, (237-250), 10.1007/s00401-019-02026-8)

EADB (Alzheimer Disease European DNA biobank), IFGC (International FTD-Genomics Consortium), IPDGC (The International Parkinson Disease Genomics Consortium), RiMod-FTD (Risk and Modifying factors in Fronto-Temporal Dementia), Netherlands Brain Bank (NBB), The GIFT (Genetic Investigation in Frontotemporal Dementia and Alzheimer’s Disease) Study Group & DESGESCO (Dementia Genetics Spanish Consortium), Jan 1 2020, (Accepted/In press) In : Acta Neuropathologica.

Research output: Contribution to journalComment/debate

Open Access

Correction to: Psychiatric disorders and SLC6A4 gene variants: possible effects on alcohol dependence and alzheimer’s disease (Molecular Biology Reports, (2020), 47, 1, (191-200), 10.1007/s11033-019-05119-5)

Calabrò, M., Mandelli, L., Crisafulli, C., Porcelli, S., Albani, D., Politis, A., Papadimitriou, G. N., Di Nicola, M., Janiri, L., Colombo, R., Martinotti, G., Bellomo, A., Vieta, E., Bonassi, S., Frustaci, A., Ducci, G., Landi, S., Boccia, S. & Serretti, A., Jan 1 2020, (Accepted/In press) In : Molecular Biology Reports.

Research output: Contribution to journalComment/debate

Open Access

Could fluorescence-guided surgery be an efficient and sustainable option? A SICE (Italian Society of Endoscopic Surgery) health technology assessment summary

Vettoretto, N., Foglia, E., Ferrario, L., Gerardi, C., Molteni, B., Nocco, U., Lettieri, E., Molfino, S., Baiocchi, G. L., Elmore, U., Rosati, R., Currò, G., Cassinotti, E., Boni, L., Cirocchi, R., Marano, A., Petz, W. L., Arezzo, A., Bonino, M. A., Davini, F. & 4 others, Biondi, A., Anania, G., Agresta, F. & Silecchia, G., Jan 1 2020, (Accepted/In press) In : Surgical Endoscopy.

Research output: Contribution to journalArticle

CSF cutoffs for MCI due to AD depend on APOEε4 carrier status

Marizzoni, M., Ferrari, C., Babiloni, C., Albani, D., Barkhof, F., Cavaliere, L., Didic, M., Forloni, G., Fusco, F., Galluzzi, S., Hensch, T., Jovicich, J., Marra, C., Molinuevo, J. L., Nobili, F., Parnetti, L., Payoux, P., Ranjeva, J. P., Ribaldi, F., Rolandi, E. & 10 others, Rossini, P. M., Salvatore, M., Soricelli, A., Tsolaki, M., Visser, P. J., Wiltfang, J., Richardson, J. C., Bordet, R., Blin, O. & Frisoni, G. B., Jan 1 2020, (Accepted/In press) In : Neurobiology of Aging.

Research output: Contribution to journalArticle

CSF cutoffs for MCI due to AD depend on APOEε4 carrier status

Marizzoni, M., Ferrari, C., Babiloni, C., Albani, D., Barkhof, F., Cavaliere, L., Didic, M., Forloni, G., Fusco, F., Galluzzi, S., Hensch, T., Jovicich, J., Marra, C., Molinuevo, J. L., Nobili, F., Parnetti, L., Payoux, P., Ranjeva, J. P., Ribaldi, F., Rolandi, E. & 10 others, Rossini, P. M., Salvatore, M., Soricelli, A., Tsolaki, M., Visser, P. J., Wiltfang, J., Richardson, J. C., Bordet, R., Blin, O. & Frisoni, G. B., Jan 1 2020, In : Neurobiol. Aging.

Research output: Contribution to journalArticle

Early osteopontin levels predict mortality in patients with septic shock

Carbone, F., Bonaventura, A., Vecchiè, A., Meessen, J., Minetti, S., Elia, E., Ferrara, D., Ansaldo, A. M., Tulli, G., Guarducci, D., Rossi, N., Bona, F., Ferrari, M., Caironi, P., Latini, R. & Montecucco, F., Jan 1 2020, (Accepted/In press) In : European Journal of Internal Medicine.

Research output: Contribution to journalArticle

Erratum: Standard (8 weeks) vs long (12 weeks) timing to minimally-invasive surgery after NeoAdjuvant Chemoradiotherapy for rectal cancer: A multicenter randomized controlled parallel group trial (TiMiSNAR) (BMC Cancer (2019) 19 (1215) DOI: 10.1186/s12885-019-6271-3)

Monsellato, I., Alongi, F., Bertocchi, E., Gori, S., Ruffo, G., Cassinotti, E., Baldari, L., Boni, L., Pernazza, G., Pulighe, F., De Nisco, C., Perinotti, R., Morpurgo, E., Contardo, T., Mammano, E., Elmore, U., Delpini, R., Rosati, R., Perna, F., Coratti, A. & 17 others, Menegatti, B., Gentilli, S., Baroffio, P., Buccianti, P., Balestri, R., Ceccarelli, C., Torri, V., Cavaliere, D., Solaini, L., Ercolani, G., Traverso, E., Fusco, V., Rossi, M., Priora, F., Numico, G., Franzone, P. & Orecchia, S., Feb 17 2020, In : BMC Cancer. 20, 1, 128.

Research output: Contribution to journalComment/debate

Open Access

Exploring the Emotional Breastfeeding Experience of First-Time Mothers: Implications for Healthcare Support

Giannì, M. L., Lanzani, M., Consales, A., Bestetti, G., Colombo, L., Bettinelli, M. E., Plevani, L., Morniroli, D., Sorrentino, G., Bezze, E., Zanotta, L., Sannino, P., Cavallaro, G., Villamor, E., Marchisio, P. & Mosca, F., May 7 2020, In : Frontiers in Pediatrics. 8, 199.

Research output: Contribution to journalArticle

Open Access

Health technology assessment–based approach to flow cytometric immunophenotyping of acute leukemias: a literature classification

on behalf of the Società Italiana di Citometria (GIC), Jan 1 2020, (Accepted/In press) In : Tumori.

Research output: Contribution to journalArticle

Identifying the optimum chest compression point during cardiopulmonary resuscitation

Olivari, D., De Giorgio, D., Fumagalli, F. & Ristagno, G., Mar 1 2020, In : Heart and Lung. 49, 2, p. 207-208 2 p.

Research output: Contribution to journalLetter

Impact of environmental factors and physical activity on disability and quality of life in CIDP

Italian CIDP Database study group, May 19 2020, In : Journal of Neurology.

Research output: Contribution to journalArticle

Industry funding of patient and health consumer organisations: Systematic review with meta-analysis

Fabbri, A., Parker, L., Colombo, C., Mosconi, P., Barbara, G., Frattaruolo, M. P., Lau, E., Kroeger, C. M., Lunny, C., Salzwedel, D. M. & Mintzes, B., Jan 1 2020, In : The BMJ. 368, l6925.

Research output: Contribution to journalReview article

Open Access

Is There Still a Role for Endocrine Therapy Alone in HR+/HER2- Advanced Breast Cancer Patients? Results from the Analysis of Two Data Sets of Patients Treated with High-Dose Fulvestrant as First-Line Therapy in the Real-World Setting: The EVA and GIM-13 AMBRA Studies

Cazzaniga, M. E., Verusio, C., Ciccarese, M., Fumagalli, A., Sartori, D., Valerio, M. R., Airoldi, M., Moretti, G., Ficorella, C., Gianni, L., Michelotti, A., Zambelli, A., Febbraro, A., Generali, D., Pistelli, M., Garrone, O., Musolino, A., Vici, P., Maur, M., Mentuccia, L. & 31 others, La Verde, N., Bianchi, G. V., Artale, S., Blasi, L., De Laurentiis, M., Atzori, F., Turletti, A., Porpiglia, M., Santini, D., Fabi, A., Gebbia, V., Schirone, A., Palumbo, R., Ferzi, A., Frassoldati, A., Scavelli, C., Clivio, L., Giordano, M., Donadio, M., Biganzoli, L., Del Mastro, L., Bisagni, G., Livi, L., Natoli, C., Montemurro, F., Riccardi, F., Romagnoli, E., Marchetti, P., Torri, V., Pronzato, P. & Mustacchi, G., Jan 1 2020, In : Breast Care. 15, p. 30-37 8 p.

Research output: Contribution to journalArticle

Knowledge and attitude of health staff towards breastfeeding in NICU setting: are we there yet? An Italian survey

Vizzari, G., Morniroli, D., Consales, A., Capelli, V., Crippa, B. L., Colombo, L., Sorrentino, G., Bezze, E., Sannino, P., Soldi, V. A., Plevani, L., Mosca, F. & Giannì, M. L., Jan 1 2020, (Accepted/In press) In : European Journal of Pediatrics.

Research output: Contribution to journalArticle

Mapping disparities in education across low- and middle-income countries

Local Burden of Disease Educational Attainment Collaborators, Jan 9 2020, In : Nature. 577, 7789, p. 235-238 4 p.

Research output: Contribution to journalArticle

Open Access

miR-129-5p: A key factor and therapeutic target in amyotrophic lateral sclerosis

Loffreda, A., Nizzardo, M., Arosio, A., Ruepp, M. D., Calogero, R. A., Volinia, S., Galasso, M., Bendotti, C., Ferrarese, C., Lunetta, C., Rizzuti, M., Ronchi, A. E., Mühlemann, O., Tremolizzo, L., Corti, S. & Barabino, S. M. L., Jan 1 2020, (Accepted/In press) In : Progress in Neurobiology. 101803.

Research output: Contribution to journalArticle

Potentially Inappropriate Medications, Drug–Drug Interactions, and Anticholinergic Burden in Elderly Hospitalized Patients: Does an Association Exist with Post-Discharge Health Outcomes?

De Vincentis, A., Gallo, P., Finamore, P., Pedone, C., Costanzo, L., Pasina, L., Cortesi, L., Nobili, A., Mannucci, P. M. & Antonelli Incalzi, R., Jan 1 2020, (Accepted/In press) In : Drugs and Aging.

Research output: Contribution to journalArticle

Predictive Impact of Mucinous Tumors on the Clinical Outcome in Patients with Poorly Differentiated, Stage II Colon Cancer: A TOSCA Subgroup Analysis

on behalf of TOSCA (Three or Six Colon Adjuvant) Investigators, Jan 1 2020, (Accepted/In press) In : Oncologist.

Research output: Contribution to journalArticle

Prognostic relevance of a blastic plasmacytoid dendritic cell neoplasm-like immunophenotype in cytogenetically normal acute myeloid leukemia patients

Guolo, F., Minetto, P., Clavio, M., Marcolin, R., Miglino, M., Passannante, M., Caviglia, F., Ballerini, F., Tedone, E., Kunkl, A., Mangerini, R., Contini, P., Colombo, N., Cagnetta, A., Cea, M., Carminati, E., Pugliese, G., Gobbi, M. & Lemoli, R. M., Jan 1 2020, (Accepted/In press) In : Leukemia and Lymphoma.

Research output: Contribution to journalArticle

Propranolol for familial cerebral cavernous malformation (Treat_CCM): study protocol for a randomized controlled pilot trial

Treat-CCM Investigators, May 12 2020, In : Trials. 21, 1, 1 p.

Research output: Contribution to journalArticle

Open Access

Safety and tolerability of ranibizumab in uni/bilateral neovascular age-related macular degeneration: 12-month TWEYEs study

Bandello, F., Staurenghi, G., Ricci, F., Midena, E., Viola, F., Lupieri Sinibaldi, T., Colombo, L., Peruzzi, E. & Bassanini, S., 2020, In : British Journal of Ophthalmology. 104, 1, p. 64-73

Research output: Contribution to journalArticle

Open Access

Selective Modulation of A1 Astrocytes by Drug-Loaded Nano-Structured Gel in Spinal Cord Injury

Vismara, I., Papa, S., Veneruso, V., Mauri, E., Mariani, A., De Paola, M., Affatato, R., Rossetti, A., Sponchioni, M., Moscatelli, D., Sacchetti, A., Rossi, F., Forloni, G. & Veglianese, P., Jan 28 2020, In : ACS Nano. 14, 1, p. 360-371 12 p.

Research output: Contribution to journalArticle

Testing longitudinal data for prognostication in ambulatory heart failure patients with reduced ejection fraction. A proof of principle from the GISSI-HF database

Canepa, M., Siri, G., Puntoni, M., Latini, R., Tavazzi, L. & Maggioni, A. P., Jan 1 2020, (Accepted/In press) In : International Journal of Cardiology.

Research output: Contribution to journalArticle

The IN-DEEP project “INtegrating and Deriving Evidence, Experiences, Preferences”: a web information model on magnetic resonance imaging for people with multiple sclerosis

Colombo, C., Confalonieri, P., Rovaris, M., La Mantia, L., Galeazzi, P., Silena Trevisan, T., Pariani, A., Gerevini, S., De Stefano, N., Guglielmino, R., Caserta, C., Mosconi, P. & Filippini, G., Jan 1 2020, (Accepted/In press) In : Journal of Neurology.

Research output: Contribution to journalArticle

The SARS-CoV-2 epidemic: how the Italian public is being informed

Antonelli, G., Capobianchi, M. R. & Riva, E., Apr 1 2020, In : Clinical Microbiology and Infection. p. 1-4 4 p.

Research output: Contribution to journalLetter

Open Access

Three-month mortality in permanently bedridden medical non-oncologic patients. The BECLAP study (permanently BEdridden, creatinine CLearance, albumin, previous hospital admissions study)

Brucato, A., Ferrari, A., Tiraboschi, M., Zucchi, A., Cogliati, C., Torzillo, D., Dentali, F., Tavecchia, L., Gessi, V., Squizzato, A., Moretti, S., Permunian, E. T., Carobbio, A., Pasina, L., De Stefano, F., Tombetti, E., Cumetti, D., Tognoni, G. & Barbui, T., Feb 2020, In : European Journal of Internal Medicine. 72, p. 60-66 7 p.

Research output: Contribution to journalArticle

Open Access

Understanding the complex of suicide in depression: From research to clinics

Orsolini, L., Latini, R., Pompili, M., Serafini, G., Volpe, U., Vellante, F., Fornaro, M., Valchera, A., Tomasetti, C., Fraticelli, S., Alessandrini, M., La Rovere, R., Trotta, S., Martinotti, G., Di Giannantonio, M. & De Berardis, D., Mar 2020, In : Psychiatry Investigation. 17, 3, p. 207-221 15 p.

Research output: Contribution to journalReview article

Open Access

Views of medical practitioners about deprescribing in older adults: Findings from an Italian qualitative study

D'Avanzo, B., Agosti, P., Reeve, E., Pasina, L., Sabbà, C., Mannucci, P. M. & Nobili, A., Apr 2020, In : Maturitas. 134, p. 29-33 5 p.

Research output: Contribution to journalArticle

2019

Addition of cyclic angiotensin-(1-7) to angiotensin-converting enzyme inhibitor therapy has a positive add-on effect in experimental diabetic nephropathy

Cassis, P., Locatelli, M., Corna, D., Villa, S., Rottoli, D., Cerullo, D., Abbate, M., Remuzzi, G., Benigni, A. & Zoja, C., Oct 2019, In : Kidney International. 96, 4, p. 906-917 12 p.

Research output: Contribution to journalArticle

Adherence to the traditional mediterranean diet and human milk composition: Rationale, design, and subject characteristics of the MEDIDIET study

Moro, G. E., Bertino, E., Bravi, F., Tonetto, P., Gatta, A., Quitadamo, P. A., Salvatori, G., Profeti, C., Nicola, P. D., Decarli, A., Ferraroni, M., Tavani, A., Stahl, B. & Wiens, F., Jan 1 2019, In : Frontiers in Pediatrics. 7, MAR, 66.

Research output: Contribution to journalArticle

Open Access

Adherence to the Traditional Mediterranean Diet and Human Milk Composition: Rationale, Design, and Subject Characteristics of the MEDIDIET Study

Moro, G. E., Bertino, E., Bravi, F., Tonetto, P., Gatta, A., Quitadamo, P. A., Salvatori, G., Profeti, C., Di Nicola, P., Decarli, A., Ferraroni, M., Tavani, A., Stahl, B. & Wiens, F., Mar 15 2019, In : Frontiers in Pediatrics. 7, p. 66

Research output: Contribution to journalArticle

A First Step toward a New Approach to Treating Membranous Nephropathy

Ruggenenti, P. & Remuzzi, G., Jul 4 2019, In : The New England journal of medicine. 381, 1, p. 86-88 3 p.

Research output: Contribution to journalArticle

Age at onset in genetic prion disease and the design of preventive clinical trials

Minikel, E. V., Vallabh, S. M., Orseth, M. C., Brandel, J. P., Haïk, S., Laplanche, J. L., Zerr, I., Parchi, P., Capellari, S., Safar, J., Kenny, J., Fong, J. C., Takada, L. T., Ponto, C., Hermann, P., Knipper, T., Stehmann, C., Kitamoto, T., Ae, R., Hamaguchi, T. & 12 others, Sanjo, N., Tsukamoto, T., Mizusawa, H., Collins, S. J., Chiesa, R., Roiter, I., De Pedro-Cuesta, J., Calero, M., Geschwind, M. D., Yamada, M., Nakamura, Y. & Mead, S., Jul 9 2019, In : Neurology. 93, 2, p. E125-E134

Research output: Contribution to journalArticle

Age at start of using tobacco on the risk of head and neck cancer: Pooled analysis in the International Head and Neck Cancer Epidemiology Consortium (INHANCE)

Chang, C. P., Chang, S. C., Chuang, S. C., Berthiller, J., Ferro, G., Matsuo, K., Wünsch-Filho, V., Toporcov, T. N., de Carvalho, M. B., La Vecchia, C., Olshan, A. F., Zevallos, J. P., Serraino, D., Muscat, J., Sturgis, E. M., Li, G., Morgenstern, H., Levi, F., Dal Maso, L., Smith, E. & 30 others, Kelsey, K., McClean, M., Vaughan, T. L., Lazarus, P., Ramroth, H., Chen, C., Schwartz, S. M., Winn, D. M., Bosetti, C., Edefonti, V., Garavello, W., Negri, E., Hayes, R. B., Purdue, M. P., Boccia, S., Cadoni, G., Shangina, O., Koifman, R., Curado, M. P., Vilensky, M., Swiatkowska, B., Herrero, R., Franceschi, S., Benhamou, S., Fernandez, L., Menezes, A. M. B., Daudt, A. W., Mates, D., Schantz, S. & Yu, G. P., Dec 2019, In : Cancer Epidemiology. 63, 8 p., 101615.

Research output: Contribution to journalArticle

Age at start of using tobacco on the risk of head and neck cancer: Pooled analysis in the International Head and Neck Cancer Epidemiology Consortium (INHANCE)

Chang, C. P., Chang, S. C., Chuang, S. C., Berthiller, J., Ferro, G., Matsuo, K., Wünsch-Filho, V., Toporcov, T. N., de Carvalho, M. B., La Vecchia, C., Olshan, A. F., Zevallos, J. P., Serraino, D., Muscat, J., Sturgis, E. M., Li, G., Morgenstern, H., Levi, F., Dal Maso, L., Smith, E. & 30 others, Kelsey, K., McClean, M., Vaughan, T. L., Lazarus, P., Ramroth, H., Chen, C., Schwartz, S. M., Winn, D. M., Bosetti, C., Edefonti, V., Garavello, W., Negri, E., Hayes, R. B., Purdue, M. P., Boccia, S., Cadoni, G., Shangina, O., Koifman, R., Curado, M. P., Vilensky, M., Swiatkowska, B., Herrero, R., Franceschi, S., Benhamou, S., Fernandez, L., Menezes, A. M. B., Daudt, A. W., Mates, D., Schantz, S. & Yu, G. P., Dec 2019, In : Cancer Epidemiology. 63, 101615.

Research output: Contribution to journalArticle

Albuminuria Regression in Diabetes: A Therapeutic Target for Nephro- and Cardio-Protection, in Clinics and Research

Ruggenenti, P. & Remuzzi, G., 2019, In : American Journal of Nephrology. 49, 2, p. 143-145 3 p.

Research output: Contribution to journalArticle

Alteration of thyroid hormone signaling triggers the diabetes-induced pathological growth, remodeling, and dedifferentiation of podocytes

Benedetti, V., Lavecchia, A. M., Locatelli, M., Brizi, V., Corna, D., Todeschini, M., Novelli, R., Benigni, A., Zoja, C., Remuzzi, G. & Xinaris, C., Sep 19 2019, In : JCI insight. 4, 18

Research output: Contribution to journalArticle

Alzheimer's Disease and Neurotransmission Gene Variants: Focus on Their Effects on Psychiatric Comorbidities and Inflammatory Parameters

Porcelli, S., Calabrò, M., Crisafulli, C., Politis, A., Liappas, I., Albani, D., Raimondi, I., Forloni, G., Benedetti, F., Papadimitriou, G. N. & Serretti, A., 2019, In : Neuropsychobiology. 78, 2, p. 79-85 7 p.

Research output: Contribution to journalArticle