Istituto Nazionale per le Malattie Infettive Lazzaro Spallanzani

Research Output 1974 2019

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2019

Acute HEV hepatitis: Clinical and laboratory diagnosis

Marrone, G., Biolato, M., Mercurio, G., Capobianchi, M. R., Garbuglia, A. R., Liguori, A., Vassallo, G., Gasbarrini, A., Miele, L. & Grieco, A., Jan 1 2019, In : European Review for Medical and Pharmacological Sciences. 23, 2, p. 764-770 7 p.

Research output: Contribution to journalArticle

Hepatitis E virus
Clinical Laboratory Techniques
Hepatitis
Virus Diseases
Developed Countries

Analysis of hepatitis B virus-mixed genotype infection by ultra deep pyrosequencing in Sudanese patients, 2015–2016

Enan, K. A., Minosse, C., El Hussein, A. R. M., Selleri, M., Giombini, E., Capobianchi, M. R., Elkhidir, I. M., Mustafa, M. O., Khair, O. M., Hassan, D. A. & Garbuglia, A. R., Jan 1 2019, In : Infection. p. 1-11 11 p.

Research output: Contribution to journalArticle

Multiplex Polymerase Chain Reaction
Coinfection
Hepatitis B virus
Genotype
Polymerase Chain Reaction

Autophagy suppresses the pathogenic immune response to dietary antigens in cystic fibrosis

Villella, V. R., Esposito, S., Ferrari, E., Monzani, R., Tosco, A., Rossin, F., Castaldo, A., Silano, M., Marseglia, G. L., Romani, L., Barlev, N. A., Piacentini, M., Raia, V., Kroemer, G. & Maiuri, L., Apr 1 2019, In : Cell Death and Disease. 10, 4, 258.

Research output: Contribution to journalArticle

Open Access
Calgranulin A
Autophagy
Cysteamine
Gliadin
Cystic Fibrosis

Characterization of QuantiFERON-TB-Plus results in latent tuberculosis infected patients with or without immune-mediated inflammatory diseases

Chiacchio, T., Petruccioli, E., Vanini, V., Cuzzi, G., Massafra, U., Baldi, G., Navarra, A., Scrivo, R., Mastroianni, C., Sauzullo, I., Esposito, C., Palmieri, F., Cantini, F. & Goletti, D., Jan 1 2019, In : Journal of Infection. p. 1-9 9 p.

Research output: Contribution to journalArticle

Latent Tuberculosis
Biological Therapy
Biological Products

Consensus document for the diagnosis of peripheral bone infection in adults: a joint paper by the EANM, EBJIS, and ESR (with ESCMID endorsement)

Glaudemans, A. W. J. M., Jutte, P. C., Cataldo, M. A., Cassar-Pullicino, V., Gheysens, O., Borens, O., Trampuz, A., Wörtler, K., Petrosillo, N., Winkler, H., Signore, A. & Sconfienza, L. M., Jan 1 2019, (Accepted/In press) In : European Journal of Nuclear Medicine and Molecular Imaging.

Research output: Contribution to journalArticle

Evidence-Based Medicine
Joints
Software Design
Bone and Bones
Nuclear Medicine

Consensus document for the diagnosis of prosthetic joint infections: a joint paper by the EANM, EBJIS, and ESR (with ESCMID endorsement)

Signore, A., Sconfienza, L. M., Borens, O., Glaudemans, A. W. J. M., Casar-Pullicino, V., Trampuz, A., Winkler, H., Gheysens, O., Vanhoenacker, F. M. H. M., Petrosillo, N. & Jutte, P. C., Jan 26 2019, In : European Journal of Nuclear Medicine and Molecular Imaging.

Research output: Contribution to journalArticle

Joints
Guidelines
Software Design
Evidence-Based Medicine
Nuclear Medicine

Daclatasvir-based regimens in HCV cirrhosis: experience from the Italian early access program

Calvaruso, V., Mazzarelli, C., Milazzo, L., Badia, L., Pasulo, L., Guaraldi, G., Lionetti, R., Villa, E., Borghi, V., Carrai, P., Alberti, A., Biolato, M., Piai, G., Persico, M., Santantonio, T., Felder, M., Angelico, M., Montalbano, M., Mancusi, R. L., Grieco, A. & 7 othersAngeli, E., D'Offizi, G., Fagiuoli, S., Belli, L., Verucchi, G., Puoti, M. & Craxì, A., Jan 24 2019, In : Scientific Reports. 9, 1, 1 p.

Research output: Contribution to journalArticle

Fibrosis
Ribavirin
Bilirubin
Antiviral Agents
Compassionate Use Trials

Decreased incidence of Kaposi sarcoma after kidney transplant in Italy and role of mTOR-inhibitors: 1997–2016

for the Italian Transplant & Cancer Cohort Study, Jan 1 2019, (Accepted/In press) In : International Journal of Cancer.

Research output: Contribution to journalArticle

Development of alkyl glycerone phosphate synthase inhibitors: Structure-activity relationship and effects on ether lipids and epithelial-mesenchymal transition in cancer cells

Stazi, G., Battistelli, C., Piano, V., Mazzone, R., Marrocco, B., Marchese, S., Louie, S. M., Zwergel, C., Antonini, L., Patsilinakos, A., Ragno, R., Viviano, M., Sbardella, G., Ciogli, A., Fabrizi, G., Cirilli, R., Strippoli, R., Marchetti, A., Tripodi, M., Nomura, D. K. & 3 othersMattevi, A., Mai, A. & Valente, S., Feb 1 2019, In : European Journal of Medicinal Chemistry. 163, p. 722-735 14 p.

Research output: Contribution to journalArticle

Epithelial-Mesenchymal Transition
Structure-Activity Relationship
Ether
Phosphates
Cells
1 Citation (Scopus)

Effectiveness of dolutegravir-based regimens as either first-line or switch antiretroviral therapy: data from the Icona cohort

ICONA Foundation Study group, Jan 1 2019, In : Journal of the International AIDS Society. 22, 1, p. e25227

Research output: Contribution to journalArticle

Therapeutics
Tenofovir
dolutegravir
Group Psychotherapy
Proportional Hazards Models
West Nile virus
Italy
Viruses
Blood Donors
Nucleic Acid Amplification Techniques

Genistein antagonizes gliadin-induced CFTR malfunction in models of celiac disease

Esposito, S., Villella, V. R., Ferrari, E., Monzani, R., Tosco, A., Rossin, F., D'Eletto, M., Castaldo, A., Luciani, A., Silano, M., Bona, G., Marseglia, G. L., Romani, L., Piacentini, M., Raia, V., Kroemer, G. & Maiuri, L., Apr 15 2019, In : Aging. 11, 7, p. 2003-2019 17 p.

Research output: Contribution to journalArticle

Gliadin
Genistein
Celiac Disease
Cystic Fibrosis
Caco-2 Cells

HIV-1 drug resistance testing is essential for heavily-treated patients switching from first- to second-line regimens in resource-limited settings: Evidence from routine clinical practice in Cameroon

Takou, D., Fokam, J., Teto, G., Santoro, M. M., Ceccherini-Silberstein, F., Nanfack, A. J., Sosso, S. M., Dambaya, B., Salpini, R., Billong, S. C., Gori, C., Fokunang, C. N., Cappelli, G., Colizzi, V., Perno, C. F. & Ndjolo, A., Mar 12 2019, In : BMC Infectious Diseases. 19, 1, 246.

Research output: Contribution to journalArticle

Open Access
Cameroon
Drug Resistance
Stavudine
HIV-1
Thymidine

Identification of a novel quinoline-based DNA demethylating compound highly potent in cancer cells

Zwergel, C., Schnekenburger, M., Sarno, F., Battistelli, C., Manara, M. C., Stazi, G., Mazzone, R., Fioravanti, R., Gros, C., Ausseil, F., Florean, C., Nebbioso, A., Strippoli, R., Ushijima, T., Scotlandi, K., Tripodi, M., Arimondo, P. B., Altucci, L., Diederich, M., Mai, A. & 1 othersValente, S., May 6 2019, In : Clinical Epigenetics. 11, 1, p. 1-18 18 p.

Research output: Contribution to journalArticle

DNA
Neoplasms
Methyltransferases
Osteosarcoma
HCT116 Cells

IgA hypogammaglobulinemia predicts outcome in chronic lymphocytic leukemia

Reda, G., Cassin, R., Gentile, M., Mauro, F. R., Giannarelli, D., Fattizzo, B., Barbieri, M., Silvestris, I., Fabris, S., Morabito, F., Neri, A., Barcellini, W. & Cortelezzi, A., Jan 1 2019, (Accepted/In press) In : Leukemia.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Improving treatment outcomes for MDR-TB — Novel host-directed therapies and personalised medicine of the future

Rao, M., Ippolito, G., Mfinanga, S., Ntoumi, F., Yeboah-Manu, D., Vilaplana, C., Zumla, A. & Maeurer, M., Mar 1 2019, In : International Journal of Infectious Diseases. 80, p. S62-S67

Research output: Contribution to journalArticle

Open Access
Precision Medicine
Therapeutics
Microbiota
Molecular Biology
Biomarkers

Increased cancer risk in patients undergoing dialysis: A population-based cohort study in North-Eastern Italy

Taborelli, M., Toffolutti, F., Del Zotto, S., Clagnan, E., Furian, L., Piselli, P., Citterio, F., Zanier, L., Boscutti, G., Serraino, D., Shalaby, S., Petrara, R., Burra, P., Zanus, G., Zanini, S., Rigotti, P., Rendina, M., Di Leo, A., Schena, F. P., Grandaliano, G. & 95 othersFiorentino, M., Lauro, A., Pinna, A. D., Di Gioia, P., Pellegrini, S., Zanfi, C., Scolari, M. P., Stefoni, S., Todeschini, P., Panicali, L., Valentini, C., Baccarani, U., Risaliti, A., Adani, G. L., Lorenzin, D., Ettorre, G. M., Vennarecci, G., Colasanti, M., Coco, M., Ettorre, F., Santoro, R., Miglioresi, L., Nudo, F., Rossi, M., Mennini, G., Toti, L., Tisone, G., Casella, A., Fazzolari, L., Sforza, D., Iaria, G., Gazia, C., Belardi, C., Cimaglia, C., Agresta, A., D'Offizi, G., Comandini, U. V., Lionetti, R., Montalbano, M., Taibi, C., Fantola, G., Zamboni, F., Piredda, G. B., Michittu, M. B., Murgia, M. G., Onano, B., Fratino, L., Maso, L. D., De Paoli, P., Verdirosi, D., Vaccher, E., Pisani, F., Famulari, A., Delreno, F., Iesari, S., De Luca, L., Iaria, M., Capocasale, E., Cremaschi, E., Sandrini, S., Valerio, F., Mazzucotelli, V., Bossini, N., Setti, G., Veroux, M., Veroux, P., Giaquinta, A., Zerbo, D., Busnach, G., Di Leo, L., Perrino, M. L., Querques, M., Colombo, V., Sghirlanzoni, M. C., Messa, P., Leoni, A., Galatioto, L., Gruttadauria, S., Sparacino, V., Caputo, F., Buscemi, B., Spagnoletti, G., Salerno, M. P., Favi, E., Segoloni, G. P., Biancone, L., Lavacca, A., Maresca, M. C., Cascone, C., Virgilio, B., Donati, D., Dossi, F., Fontanella, A., Ambrosini, A. & Di Cicco, M., Mar 28 2019, In : BMC Nephrology. 20, 1, 107.

Research output: Contribution to journalArticle

Open Access
Italy
Dialysis
Cohort Studies
Confidence Intervals
Population

Integrase strand transfer inhibitor-based regimen is related with a limited HIV-1 V3 loop evolution in clinical practice

Alteri, C., Scutari, R., Bertoli, A., Armenia, D., Gori, C., Fabbri, G., Mastroianni, C. M., Cerva, C., Cristaudo, A., Vicenti, I., Bruzzone, B., Zazzi, M., Andreoni, M., Antinori, A., Svicher, V., Ceccherini-Silberstein, F., Perno, C. F. & Santoro, M. M., Jan 1 2019, In : Virus Genes.

Research output: Contribution to journalArticle

Integrases
HIV-1
Viral Load
Odds Ratio
Confidence Intervals

Is the rate of virological failure to cART continuing to decline in recent calendar years?

for the Icona Foundation Study Group, Jul 1 2019, In : Journal of Clinical Virology. 116, p. 23-28 6 p.

Research output: Contribution to journalArticle

HIV
Therapeutics
HIV-1
Education
Calendars

Laboratory management of Crimean-Congo haemorrhagic fever virus infections: Perspectives from two European networks

Bartolini, B., Gruber, C. E. M., Koopmans, M., Avšič, T., Bino, S., Christova, I., Grunow, R., Hewson, R., Korukluoglu, G., Lemos, C. M., Mirazimi, A., Papa, A., Sanchez-Seco, M. P., Sauer, A. V., Zeller, H., Nisii, C., Capobianchi, M. R., Ippolito, G., Reusken, C. B. & Di Caro, A., Jan 31 2019, In : Eurosurveillance. 24, 5, 1800093.

Research output: Contribution to journalArticle

Open Access
Crimean-Congo hemorrhagic fever virus
Virus Diseases
Expert Testimony
Disease Outbreaks
Emerging Communicable Diseases
1 Citation (Scopus)

Latent TB Infection (LTBI) – Mycobacterium tuberculosis pathogenesis and the dynamics of the granuloma battleground

Rao, M., Ippolito, G., Mfinanga, S., Ntoumi, F., Yeboah-Manu, D., Vilaplana, C., Zumla, A. & Maeurer, M., Mar 1 2019, In : International Journal of Infectious Diseases. 80, p. S58-S61 4 p.

Research output: Contribution to journalArticle

Open Access
Granuloma
Mycobacterium tuberculosis
Infection
Implosive Therapy
Latent Tuberculosis

Meningitis with cranial polyneuritis and cavernous sinus thrombosis by Borrelia crocidurae: First autochthonous case in Europe

Malincarne, L., Schiaroli, E., Ciervo, A., Scaglione, V., Paciaroni, M., Mancini, F., Paglia, M. G., Cardaci, S., Pasticci, M. B., Francisci, D. & Baldelli, F., May 1 2019, In : International Journal of Infectious Diseases. 82, p. 30-32 3 p.

Research output: Contribution to journalArticle

Open Access
Cavernous Sinus Thrombosis
Ornithodoros
Intracranial Sinus Thrombosis
Borrelia
Neuritis
4 Citations (Scopus)

Mesothelioma and thymic tumors: Treatment challenges in (outside) a network setting

RARECAREnet Working Group, Jan 1 2019, In : European Journal of Surgical Oncology. 45, 1, p. 75-80 6 p.

Research output: Contribution to journalArticle

Thymus Neoplasms
Mesothelioma
Public Opinion
Translational Medical Research
Neoplasms

Migrainous Infarction in a Patient With Sporadic Hemiplegic Migraine and Cystic Fibrosis: A 99mTc-HMPAO Brain SPECT Study

Mancini, V., Mastria, G., Frantellizzi, V., Troiani, P., Zampatti, S., Carboni, S., Giardina, E., Campopiano, R., Gambardella, S., Turchi, F., Petolicchio, B., Toscano, M., Liberatore, M., Viganò, A. & Di Piero, V., Feb 1 2019, In : Headache. 59, 2, p. 253-258 6 p.

Research output: Contribution to journalArticle

Technetium Tc 99m Exametazime
Single-Photon Emission-Computed Tomography
Cystic Fibrosis
Infarction
Cortical Spreading Depression
Organizations
Biotechnology
Research
Technology Transfer
Accreditation
Orthopoxvirus
Seroepidemiologic Studies
Italy
Cats
Veterinarians

PD-1 in human NK cells: evidence of cytoplasmic mRNA and protein expression

Mariotti, F. R., Petrini, S., Ingegnere, T., Tumino, N., Besi, F., Scordamaglia, F., Munari, E., Pesce, S., Marcenaro, E., Moretta, A., Vacca, P. & Moretta, L., Dec 25 2019, In : OncoImmunology. 8, 3, p. 1557030

Research output: Contribution to journalArticle

Natural Killer Cells
Messenger RNA
Proteins
Peripheral Tolerance
Tumor Microenvironment

Point prevalence survey of healthcare-associated infections and antimicrobial use in Kosovo hospitals

Raka, L., Spahija, G., Gashi-Gecaj, A., Hamza, A., Haxhiu, E., Rashiti, A., Rrahimi, G., Hyseni, S. & Petrosillo, N., Jan 1 2019, In : Infectious Disease Reports. 11, 1, 7975.

Research output: Contribution to journalArticle

Open Access
Kosovo
Cross Infection
Anti-Bacterial Agents
Surveys and Questionnaires
Surgical Wound Infection
efavirenz
etravirine
Rilpivirine
Reverse Transcriptase Inhibitors
HIV-1
Open Access
Multidrug-Resistant Tuberculosis
Drug-Related Side Effects and Adverse Reactions
tuberculosis
Tertiary Care Centers
Italy

Randomized clinical trial on efficacy of fixed-dose efavirenz/tenofovir/emtricitabine on alternate days versus continuous treatment

ATAD Study Group, Bellagamba, R., Giancola, M. L., Tommasi, C., Piselli, P., Tempestilli, M., Angeletti, C., Zaccarelli, M., Ammassari, A., Pinnetti, C., Gallo, A. L., Antinori, A., Narciso, P. & Nicastri, E., Mar 1 2019, In : AIDS (London, England). 33, 3, p. 493-502 10 p.

Research output: Contribution to journalArticle

Tenofovir
efavirenz
Randomized Controlled Trials
Therapeutics
CD4 Lymphocyte Count
Aspergillosis
Therapeutics
Cytarabine
Mortality
Numbers Needed To Treat

Real life experiences in HCV management in 2018

Viganò, M., Andreoni, M., Perno, C. F., Craxì, A., Aghemo, A., Alberti, A., Andreone, P., Babudieri, S., Bonora, S., Brunetto, M. R., Bruno, R., Bruno, S., Calvaruso, V., Caporaso, N., Cartabellotta, F., Ceccherini-Silberstein, F., Cento, V., Ciancio, A., Colombatto, P., Coppola, N. & 13 othersDi Marco, V., Di Perri, G., Fagiuoli, S., Gaeta, G. B., Gasbarrini, A., Lampertico, P., Pellicelli, A., Prestileo, T., Puoti, M., Raimondo, G., Rizzardini, G., Taliani, G. & Zignego, A. L., 2019, In : Expert Review of Anti-Infective Therapy. 17, 2, p. 117-128 12 p.

Research output: Contribution to journalArticle

Real life experiences in HCV management in 2018 AU - Viganò, Mauro

Andreoni, M., Perno, C. F., Craxì, A., Aghemo, A., Alberti, A., Andreone, P., Babudieri, S., Bonora, S., Brunetto, M. R., Bruno, R., Bruno, S., Calvaruso, V., Caporaso, N., Cartabellotta, F., Ceccherini-Silberstein, F., Cento, V., Ciancio, A., Colombatto, P., Coppola, N., Di Marco, V. & 12 othersDi Perri, G., Fagiuoli, S., Gaeta, G. B., Gasbarrini, A., Lampertico, P., Pellicelli, A., Prestileo, T., Puoti, M., Raimondo, G., Rizzardini, G., Taliani, G. & Zignego, A. L., Feb 1 2019, In : Expert Review of Anti-Infective Therapy. 17, 2, p. 117-128 12 p.

Research output: Contribution to journalArticle

Secretome of adipose-derived mesenchymal stem cells promotes skeletal muscle regeneration through synergistic action of extracellular vesicle cargo and soluble proteins

Mitchell, R., Mellows, B., Sheard, J., Antonioli, M., Kretz, O., Chambers, D., Zeuner, M. T., Tomkins, J. E., Denecke, B., Musante, L., Joch, B., Debacq-Chainiaux, F., Holthofer, H., Ray, S., Huber, T. B., Dengjel, J., De Coppi, P., Widera, D. & Patel, K., Apr 5 2019, In : Stem Cell Research and Therapy. 10, 1, 116.

Research output: Contribution to journalArticle

Open Access
Stem cells
Mesenchymal Stromal Cells
Muscle
Regeneration
Skeletal Muscle

Severe chest allodynia as an unusual first presentation of hydatid disease: A case report

Coluzzi, F., Meniconi, R. L., Caruso, D., Rivosecchi, F., Petrone, L., Goletti, D. & Ettorre, G. M., Jan 9 2019, In : BMC Infectious Diseases. 19, 1, 37.

Research output: Contribution to journalArticle

Echinococcosis
Hyperalgesia
Cysts
Rupture
Thorax

Surveillance of adverse events in the treatment of drug-resistant tuberculosis: A global feasibility study

The members of the International Study Group on new anti-tuberculosis drugs and adverse events monitoring, Jun 1 2019, In : International Journal of Infectious Diseases. 83, p. 72-76 5 p.

Research output: Contribution to journalArticle

Open Access
bedaquiline
Multidrug-Resistant Tuberculosis
Feasibility Studies
Tuberculosis
Pharmaceutical Preparations

Survival after the diagnosis of de novo malignancy in liver transplant recipients

Italian Transplant and Cancer Cohort Study, Jan 15 2019, In : International Journal of Cancer. 144, 2, p. 232-239 8 p.

Research output: Contribution to journalArticle

Survival
Liver
Confidence Intervals
Neoplasms
Transplants

The role of procalcitonin outside of the Intensive Care Unit (ICU): A multidisciplinary approach

Fantoni, M., Taddei, E., Cauda, R., Antonelli Incalzi, R., Capone, A., Cortese, F., Sanguinetti, M., Spandonaro, F., Urbani, A. & Murri, R., Jan 1 2019, In : European Review for Medical and Pharmacological Sciences. 23, 7, p. 2978-2985 8 p.

Research output: Contribution to journalArticle

Calcitonin
Intensive Care Units
Infectious Disease Medicine
Medical Economics
Clinical Chemistry

Tick-borne encephalitis in Europe: a brief update on epidemiology, diagnosis, prevention, and treatment

Riccardi, N., Antonello, R. M., Luzzati, R., Zajkowska, J., Di Bella, S. & Giacobbe, D. R., Jan 1 2019, (Accepted/In press) In : European Journal of Internal Medicine.

Research output: Contribution to journalArticle

Tick-Borne Encephalitis
Epidemiology
Therapeutics
Central Nervous System Infections
Immunocompromised Host

Tropism of the chikungunya virus

Matusali, G., Colavita, F., Bordi, L., Lalle, E., Ippolito, G., Capobianchi, M. R. & Castilletti, C., Feb 1 2019, In : Viruses. 11, 2, 175.

Research output: Contribution to journalArticle

Open Access
Chikungunya virus
Tropism
Hong Kong
Culicidae
Vertebrates
1 Citation (Scopus)

Tuberculin skin test – Outdated or still useful for Latent TB infection screening?

Gualano, G., Mencarini, P., Lauria, F. N., Palmieri, F., Mfinanga, S., Mwaba, P., Chakaya, J., Zumla, A. & Ippolito, G., Mar 1 2019, In : International Journal of Infectious Diseases. 80, p. S20-S22

Research output: Contribution to journalArticle

Open Access
Tuberculin Test
Interferon-gamma Release Tests
Skin Tests
Infection
Uncertainty
2018

Accuracy of lung cancer ICD-9-CM codes in Umbria, Napoli 3 Sud and Friuli Venezia Giulia administrative healthcare databases: A diagnostic accuracy study

Montedori, A., Bidoli, E., Serraino, D., Fusco, M., Giovannini, G., Casucci, P., Franchini, D., Granata, A., Ciullo, V., Vitale, M. F., Gobbato, M., Chiari, R., Cozzolino, F., Orso, M., Orlandi, W. & Abraha, I., May 1 2018, In : BMJ Open. 8, 5, e020628.

Research output: Contribution to journalArticle

International Classification of Diseases
Lung Neoplasms
Databases
Delivery of Health Care
Documentation
1 Citation (Scopus)

Acute phase proteins and IP-10 as triage tests for the diagnosis of tuberculosis: systematic review and meta-analysis

Santos, V. S., Goletti, D., Kontogianni, K., Adams, E. R., Molina-Moya, B., Dominguez, J., Crudu, V., Martins-Filho, P. R. S., Ruhwald, M., Lawson, L., Bimba, J. S., Garcia-Basteiro, A. L., Petrone, L., Kabeer, B. S., Reither, K. & Cuevas, L. E., Aug 1 2018, In : Clinical Microbiology and Infection.

Research output: Contribution to journalArticle

Acute-Phase Proteins
Triage
Meta-Analysis
Tuberculosis
Sensitivity and Specificity