Research Output

Article

Activated T lymphocytes in patients with multiple sclerosis

Golaz, J., Steck, A. & Moretta, L., 1983, In : Neurology. 33, 10, p. 1371-1373 3 p.

Research output: Contribution to journalArticle

Activating Killer Immunoglobulin Receptors and HLA-C: a successful combination providing HIV-1 control

Malnati, M. S., Ugolotti, E., Monti, M. C., Battista, D. D., Vanni, I., Bordo, D., Sironi, F., Larghero, P., Marco, E. D., Biswas, P., Poli, G., Vicenzi, E., Riva, A., Tarkowski, M., Tambussi, G., Nozza, S., Tripodi, G., Marras, F., De Maria, A., Pistorio, A. & 1 others, Biassoni, R., Feb 13 2017, In : Scientific Reports. 7, p. 42470

Research output: Contribution to journalArticle

Activating Killer Immunoglobulin Receptors and HLA-C: A successful combination providing HIV-1 control

Malnati, MS., Ugolotti, E., Monti, MC., De Battista, D., Vanni, I., Bordo, D., Sironi, F., Larghero, P., Di Marco, E., Biswas, P., Poli, G., Vicenzi, E., Riva, A., Tarkowski, M., Tambussi, G., Nozza, S., Tripodi, G., Marras, F., De Maria, A., Pistorio, A. & 1 others, Biassoni, R., 2017, In : Scientific Reports. 7, 25, 42470.

Research output: Contribution to journalArticle

Activating KIRs and NKG2C in viral infections: Toward NK cell memory?

Chiesa, M. D., Sivori, S., Carlomagno, S., Moretta, L. & Moretta, A., 2015, In : Frontiers in Immunology. 6, NOV, 573.

Research output: Contribution to journalArticle

Activating MRAS mutations cause Noonan syndrome associated with hypertrophic cardiomyopathy

Motta, M., Sagi-Dain, L., Krumbach, O. H. F., Hahn, A., Peleg, A., German, A., Lissewski, C., Coppola, S., Pantaleoni, F., Kocherscheid, L., Altmüller, F., Schanze, D., Logeswaran, T., Chahrokh-Zadeh, S., Munzig, A., Nakhaei-Rad, S., Cavé, H., Ahmadian, M. R., Tartaglia, M. & Zenker, M., May 21 2019, In : Human Molecular Genetics.

Research output: Contribution to journalArticle

Activating Mutations Affecting the Dbl Homology Domain of SOS2 Cause Noonan Syndrome

Cordeddu, V., Yin, J. C., Gunnarsson, C., Virtanen, C., Drunat, S., Lepri, F., De Luca, A., Rossi, C., Ciolfi, A., Pugh, T. J., Bruselles, A., Priest, J. R., Pennacchio, L. A., Lu, Z., Danesh, A., Quevedo, R., Hamid, A., Martinelli, S., Pantaleoni, F., Gnazzo, M. & 19 others, Daniele, P., Lissewski, C., Bocchinfuso, G., Stella, L., Odent, S., Philip, N., Faivre, L., Vlckova, M., Seemanova, E., Digilio, C., Zenker, M., Zampino, G., Verloes, A., Dallapiccola, B., Roberts, A. E., Cavé, H., Gelb, B. D., Neel, B. G. & Tartaglia, M., Nov 1 2015, In : Human Mutation. 36, 11, p. 1080-1087 8 p.

Research output: Contribution to journalArticle

Activating mutations in RRAS underlie a phenotype within the RASopathy spectrum and contribute to leukaemogenesis

Flex, E., Jaiswal, M., Pantaleoni, F., Martinelli, S., Strullu, M., Fansa, E. K., Caye, A., De Luca, A., Lepri, F., Dvorsky, R., Pannone, L., Paolacci, S., Zhang, S. C., Fodale, V., Bocchinfuso, G., Rossi, C., Burkitt-Wright, E. M. M., Farrotti, A., Stellacci, E., Cecchetti, S. & 28 others, Ferese, R., Bottero, L., Castro, S., Fenneteau, O., Brethon, B., Sanchez, M., Roberts, A. E., Yntema, H. G., Van Der Burgt, I., Cianci, P., Bondeson, M. L., Digilio, M. C., Zampino, G., Kerr, B., Aoki, Y. K., Loh, M. L., Palleschi, A., Di Schiavi, E., Caré, A., Selicorni, A., Dallapiccola, B., Cirstea, I. C., Stella, L., Zenker, M., Gelb, B. D., Cavé, H., Ahmadian, M. R. & Tartaglia, M., 2014, In : Human Molecular Genetics. 23, 16, p. 4315-4327 13 p., ddu148.

Research output: Contribution to journalArticle

Activating Mutations of RRAS2 Are a Rare Cause of Noonan Syndrome

Capri, Y., Flex, E., Krumbach, O. H. F., Carpentieri, G., Cecchetti, S., Lißewski, C., Rezaei Adariani, S., Schanze, D., Brinkmann, J., Piard, J., Pantaleoni, F., Lepri, F. R., Goh, E. S-Y., Chong, K., Stieglitz, E., Meyer, J., Kuechler, A., Bramswig, N. C., Sacharow, S., Strullu, M. & 13 others, Vial, Y., Vignal, C., Kensah, G., Cuturilo, G., Kazemein Jasemi, N. S., Dvorsky, R., Monaghan, K. G., Vincent, L. M., Cavé, H., Verloes, A., Ahmadian, M. R., Tartaglia, M. & Zenker, M., Jun 6 2019, In : American Journal of Human Genetics. 104, 6, p. 1223-1232 10 p.

Research output: Contribution to journalArticle

Activating NK cell receptor expression/function (NKp30, NKp46, DNAM-1) during chronic viraemic HCV infection is associated with the outcome of combined treatment

Bozzano, F., Picciotto, A., Costa, P., Marras, F., Fazio, V., Hirsch, I., Olive, D., Moretta, L. & de Maria, A., Oct 2011, In : European Journal of Immunology. 41, 10, p. 2905-2914 10 p.

Research output: Contribution to journalArticle

Activating PIK3CA somatic mutation in congenital unilateral isolated muscle overgrowth of the upper extremity

Castiglioni, C., Bertini, E., Orellana, P., Villarroel, C., Las Heras, F., Hinzpeter, D., Paolinelli, P., Bevilacqua, J. A. & Alvarez, K., 2014, In : American Journal of Medical Genetics, Part A. 164, 9, p. 2365-2369 5 p.

Research output: Contribution to journalArticle

Activating PTPN11 mutations play a minor role in pediatric and adult solid tumors

Martinelli, S., Carta, C., Flex, E., Binni, F., Cordisco, E. L., Moretti, S., Puxeddu, E., Tonacchera, M., Pinchera, A., McDowell, H. P., Dominici, C., Rosolen, A., Di Rocco, C., Riccardi, R., Celli, P., Picardo, M., Genuardi, M., Grammatico, P., Sorcini, M. & Tartaglia, M., Apr 15 2006, In : Cancer Genetics and Cytogenetics. 166, 2, p. 124-129 6 p.

Research output: Contribution to journalArticle

Activation-induced cell death and Fas-induced apoptosis in patients with systemic or pauciarticular juvenile idiopathic arthritis

Pignatti, P., Massa, M., Travaglino, P., Meazza, C., Martini, A. & De Benedetti, A. M. F., 2001, In : Clinical and Experimental Rheumatology. 19, 3, p. 339-344 6 p.

Research output: Contribution to journalArticle

Activation-induced cytidine deaminase (AID) deficiency causes the autosomal recessive form of the hyper-IgM syndrome (HIGM2)

Revy, P., Muto, T., Levy, Y., Geissmann, F., Plebani, A., Sanal, O., Catalan, N., Forveille, M., Dufourcq-Lagelouse, R., Gennery, A., Tezcan, I., Ersoy, F., Kayserili, H., Ugazio, A. G., Brousse, N., Muramatsu, M., Notarangelo, L. D., Kinoshita, K., Honjo, T., Fischer, A. & 1 others, Durandy, A., Sep 1 2000, In : Cell. 102, 5, p. 565-575 11 p.

Research output: Contribution to journalArticle

Activation of an endothelial Notch1-Jagged1 circuit induces VCAM1 expression, an effect amplified by interleukin-1β

Verginelli, F., Adesso, L., Limon, I., Alisi, A., Gueguen, M., Panera, N., Giorda, E., Raimondi, L., Ciarapica, R., Campese, A. F., Screpanti, I., Stifani, S., Kitajewski, J., Miele, L., Rota, R. & Locatelli, F., 2015, In : Oncotarget. 6, 41, p. 43216-43229 14 p.

Research output: Contribution to journalArticle

Activation of autophagy, observed in liver tissues from patients with Wilson disease and from Atp7b-deficient animals, protects hepatocytes from copper-induced apoptosis

Polishchuk, E. V., Merolla, A., Lichtmannegger, J., Romano, A., Indrieri, A., Ilyechova, E. Y., Concilli, M., De Cegli, R., Crispino, R., Mariniello, M., Petruzzelli, R., Ranucci, G., Iorio, R., Pietrocola, F., Einer, C., Borchard, S., Zibert, A., Schmidt, H. H., Di Schiavi, E., Puchkova, L. V. & 4 others, Franco, B., Kroemer, G., Zischka, H. & Polishchuk, R. S., Nov 16 2018, In : Gastroenterology.

Research output: Contribution to journalArticle

Activation of Ca2+-dependent K+ and Cl- currents by UTP and ATP in CFPAC-1 cells

Galietta, L. J. V., Zegarra-Moran, O., Mastrocola, T., Wöhrle, C., Rugolo, M. & Romeo, G., Apr 1994, In : Pflugers Archiv European Journal of Physiology. 426, 6, p. 534-541 8 p.

Research output: Contribution to journalArticle

Activation of COL3A1 promoter activity by cyclosporine

Ginevri, F., Gusmano, R., Oleggini, R., Valenti, F., Botti, G., Musante, L., Candiano, G., Ravazzolo, R. & Ghiggeri, G. M., 1998, In : Transplantation Proceedings. 30, 4, p. 955-956 2 p.

Research output: Contribution to journalArticle

Activation of double-stranded RNA dependent protein kinase by ribosomal RNA precursors

Bottazzi, B., Clayton, M. & Varesio, L., Oct 1987, In : Cytotechnology. 1, 1, p. 57-60 4 p.

Research output: Contribution to journalArticle

Activation of G551D CFTR channel with MPB-91: Regulation by ATPase activity and phosphorylation

Dérand, R., Bulteau-Pignoux, L., Mettey, Y., Zegarra-Moran, O., Howell, L. D., Randak, C., Galietta, L. J. V., Cohn, J. A., Norez, C., Romio, L., Vierfond, J. M., Joffre, M. & Becq, F., 2001, In : American Journal of Physiology - Cell Physiology. 281, 5 50-5

Research output: Contribution to journalArticle

Activation of hepatic stem cells compartment during hepatocarcinogenesis in a HBsAg HBV-transgenic mouse model

Anfuso, B., El-Khobar, K. E., Ie, S. I., Avellini, C., Radillo, O., Raseni, A., Tiribelli, C. & Sukowati, C. H. C., Dec 1 2018, In : Scientific Reports. 8, 1, 13168.

Research output: Contribution to journalArticle

Activation of human immunodeficiency virus long terminal repeat by arachidonic acid

Carini, R., Leonarduzzi, G., Camandola, S., Musso, T., Varesio, L., Baeuerle, P. A. & Poli, G., 1996, In : Free Radical Biology and Medicine. 22, 1-2, p. 195-199 5 p.

Research output: Contribution to journalArticle

Activation of human NK cells by plasmacytoid dendritic cells and its modulation by CD4+ T helper cells and CD4+ CD25hi T regulatory cells

Romagnani, C., Della Chiesa, M., Kohler, S., Moewes, B., Radbruch, A., Moretta, L., Moretta, A. & Thiel, A., Aug 2005, In : European Journal of Immunology. 35, 8, p. 2452-2458 7 p.

Research output: Contribution to journalArticle

Activation of human peripheral blood lymphocytes: Effect of concanavalin A and lipopolysaccharide on in vitro synthesis of DNA and immunoglobulins

Nespoli, L., Vitiello, A., Maccario, R., Lanzavecchia, A. & Ugazio, A. G., 1980, In : Scandinavian Journal of Immunology. 12, 2, p. 165-170 6 p.

Research output: Contribution to journalArticle

Activation of immature dendritic cells via membrane sialophorin (CD43)

Fanales-Belasio, E., Zambruno, G., Cavani, A. & Girolomoni, G., 1997, In : Advances in Experimental Medicine and Biology. 417, p. 207-212 6 p.

Research output: Contribution to journalArticle

Activation of murine macrophages. I. Different pattern of activation by Poly I: C than by lymphokine or LPS

Taramelli, D. & Varesio, L., 1981, In : Journal of Immunology. 127, 1, p. 58-63 6 p.

Research output: Contribution to journalArticle

Activation of NADPH oxidase and phosphorylation of membrane proteins in human neutrophils: Coordinate inhibition by a surface antigen-directed monoclonal antibody

Pontremoli, S., Melloni, E., Salamino, F., Sparatore, B., Michetti, M., Sacco, O. & Horecker, B. L., Nov 14 1986, In : Biochemical and Biophysical Research Communications. 140, 3, p. 1121-1126 6 p.

Research output: Contribution to journalArticle

Activation of PKC-β isoforms mediates HNE-induced MCP-1 release by macrophages

Nitti, M., Domenicotti, C., D'Abramo, C., Assereto, S., Cottalasso, D., Melloni, E., Poli, G., Biasi, F., Marinari, U. M. & Pronzato, M. A., 2002, In : Biochemical and Biophysical Research Communications. 294, 3, p. 547-552 6 p.

Research output: Contribution to journalArticle

Activation of T cells via tumor antigen specific chimeric receptors: The role of the intracellular signaling domain

Losch, F. O., Müller, R., Mutschler, B., Neri, D., Natali, P. G., Reth, M. & Carsetti, R., Jan 20 2003, In : International Journal of Cancer. 103, 3, p. 399-407 9 p.

Research output: Contribution to journalArticle

Activation of the intracellular glutathione system by oxydative stress during cardiopulmonary bypass and myocardial perfusion

Tao, S., Calza, G., Lerzo, F., Virgone, A., Camassa, N., Panizzon, G., Bertolini, A., Brunelli, L., Moretti, R., Grasso, P. & Ghiggeri, G., 1995, In : Perfusion. 10, 1, p. 45-50 6 p.

Research output: Contribution to journalArticle

Activation of the nitric oxide synthase pathway represents a key component of tumor necrosis factor-related apoptosis-inducing ligand-mediated cytotoxicity on hematologic malignancies

Secchiero, P., Gonelli, A., Celeghini, C., Mirandola, P., Guidotti, L., Visani, G., Capitani, S. & Zauli, G., Oct 1 2001, In : Blood. 98, 7, p. 2220-2228 9 p.

Research output: Contribution to journalArticle

Activation of the p53 pathway down-regulates the osteoprotegerin expression and release by vascular endothelial cells

Secchiero, P., Corallini, F., Rimondi, E., Chiaruttini, C., Grazia Di Iasio, M., Rustighi, A., Del Sal, G. & Zauli, G., 2008, In : Blood. 111, 3, p. 1287-1294 8 p.

Research output: Contribution to journalArticle

Activation of the p53 pathway induces α-smooth muscle actin expression in both myeloid leukemic cells and normal macrophages

Secchiero, P., Rimondi, E., di Iasio, M. G., Voltan, R., Gonelli, A. & Zauli, G., May 2012, In : Journal of Cellular Physiology. 227, 5, p. 1829-1837 9 p.

Research output: Contribution to journalArticle

Activation of the transcription factor EB rescues lysosomal abnormalities in cystinotic kidney cells

Rega, L. R., Polishchuk, E., Montefusco, S., Napolitano, G., Tozzi, G., Zhang, J., Bellomo, F., Taranta, A., Pastore, A., Polishchuk, R., Piemonte, F., Medina, D. L., Catz, S. D., Ballabio, A. & Emma, F., Apr 1 2016, In : Kidney International. 89, 4, p. 862-873 12 p.

Research output: Contribution to journalArticle

Activation of tumoricidal and/or suppressor macrophages: different stimulatory signals trigger either function both in vivo and in vitro.

Taramelli, D., Bagley, M. B., Holden, H. T. & Varesio, L., 1982, In : Advances in Experimental Medicine and Biology. 155, p. 487-492 6 p.

Research output: Contribution to journalArticle

Active focal segmental glomerulosclerosis is associated with massive oxidation of plasma albumin

Musante, L., Candiano, G., Petretto, A., Bruschi, M., Dimasi, N., Caridi, G., Pavone, B., Del Boccio, P., Galliano, M., Urbani, A., Scolari, F., Vincenti, F. & Ghiggeri, G. M., Mar 2007, In : Journal of the American Society of Nephrology. 18, 3, p. 799-810 12 p.

Research output: Contribution to journalArticle

Active or recent parvovirus B19 infection in children with Kawasaki disease

Nigro, G., Krzysztofiak, A., Porcaro, M. A., Mango, T., Zerbini, M., Gentilomi, G. & Musiani, M., May 21 1994, In : Lancet. 343, 8908, p. 1260-1261 2 p.

Research output: Contribution to journalArticle

Active prophylaxis for RSV: state of art

Vittucci, A. C., Zangari, P., Ciarlitto, C., Di Camillo, C., Grandin, A., Cotugno, N., Marchili, M. R. & Villani, A., Oct 18 2018, In : Minerva Pediatrica.

Research output: Contribution to journalArticle

Active retinitis in an infant with postnatally acquired cytomegalovirus infection

Piersigilli, F., Catena, G., De Gasperis, M. R., Lozzi, S. & Auriti, C., Jul 2012, In : Journal of Perinatology. 32, 7, p. 559-562 4 p.

Research output: Contribution to journalArticle

Active thymus derived suppressor lymphocytes in human cord blood

Oldstone, M. B. A., Tishon, A. & Moretta, L., 1977, In : Nature. 269, 5626, p. 333-335 3 p.

Research output: Contribution to journalArticle

ActivinA: a new leukemia-promoting factor conferring migratory advantage to B-cell precursor-acute lymphoblastic leukemic cells

Portale, F., Cricrì, G., Bresolin, S., Lupi, M., Gaspari, S., Silvestri, D., Russo, B., Marino, N., Ubezio, P., Pagni, F., Vergani, P., Te Kronnie, G., Valsecchi, M. G., Locatelli, F., Rizzari, C., Biondi, A., Dander, E. & D'Amico, G., Sep 27 2018, In : Haematologica.

Research output: Contribution to journalArticle

ACTIVITE PRO-OEDEMATEUSE DE LA LACIDIPINE, DE LA NITRENDIPINE ET DE LA NIFEDIPINE CHEZ LE RAT SPONTANEMENT HYPERTENDU

Translated title of the contribution: Peripheral edema formation with lacidipine, nitrendipine and nifedipine in spontaneously hypertensive ratsRota, R., Pallotta, M., Garay, R., Giraud, F., Courseau, C. & Hannaert, P., 1994, In : Archives des Maladies du Coeur et des Vaisseaux. 87, 8, p. 975-977 3 p.

Research output: Contribution to journalArticle

Activity of budesonide on nasal neutrophilic inflammation and obstruction in children with recurrent upper airway infections: A preliminary investigation

Bellodi, S., Tosca, M. A., Pulvirenti, G., Petecchia, L., Serpero, L., Silvestri, M., Sabatini, F., Battistini, E. & Rossi, G. A., Mar 2006, In : International Journal of Pediatric Otorhinolaryngology. 70, 3, p. 445-452 8 p.

Research output: Contribution to journalArticle

Activity of classical and alternative pathways of complement in preterm and small for gestational age infants

Notarangelo, L. D., Chirico, G., Chiara, A., Colombo, A., Rondini, G., Plebani, A., Martini, A. & Ugazio, A. G., 1984, In : Pediatric Research. 18, 3, p. 281-285 5 p.

Research output: Contribution to journalArticle

Activity of the novel mTOR inhibitor Torin-2 in B-precursor acute lymphoblastic leukemia and its therapeutic potential to prevent Akt reactivation

Simioni, C., Cani, A., Martelli, A. M., Zauli, G., Tabellini, G., McCubrey, J., Capitani, S. & Neri, L. M., 2014, In : Oncotarget. 5, 20, p. 10034-10047 14 p.

Research output: Contribution to journalArticle

Activity of the pan-class I phosphoinositide 3-kinase inhibitor NVP-BKM120 in T-cell acute lymphoblastic leukemia

Lonetti, A., Antunes, I. L., Chiarini, F., Orsini, E., Buontempo, F., Ricci, F., Tazzari, P. L., Pagliaro, P., Melchionda, F., Pession, A., Bertaina, A., Locatelli, F., Mccubrey, J. A., Barata, J. T. & Martelli, A. M., 2014, In : Leukemia. 28, 6, p. 1196-1206 11 p.

Research output: Contribution to journalArticle