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Research Output

2017

Dihydropyrimidine dehydrogenase pharmacogenetics for predicting fluoropyrimidine-related toxicity in the randomised, phase III adjuvant TOSCA trial in high-risk colon cancer patients

Ruzzo, A., Graziano, F., Galli, F., Galli, F., Rulli, E., Lonardi, S., Ronzoni, M., Massidda, B., Zagonel, V., Pella, N., Mucciarini, C., Labianca, R., Ionta, M. T., Bagaloni, I., Veltri, E., Sozzi, P., Barni, S., Ricci, V., Foltran, L., Nicolini, M. & 10 others, Biondi, E., Bramati, A., Turci, D., Lazzarelli, S., Verusio, C., Bergamo, F., Sobrero, A., Frontini, L., Menghi, M. & Magnani, M., Oct 24 2017, In : British Journal of Cancer. 117, 9, p. 1269-1277 9 p.

Research output: Contribution to journalArticle

Dihydropyrimidine dehydrogenase pharmacogenetics for predicting fluoropyrimidine-related toxicity in the randomised, phase III adjuvant TOSCA trial in high-risk colon cancer patients

Ruzzo, A., Graziano, F., Galli, F., Rulli, E., Lonardi, S., Ronzoni, M., Massidda, B., Zagonel, V., Pella, N., Mucciarini, C., Labianca, R., Ionta, M. T., Bagaloni, I., Veltri, E., Sozzi, P., Barni, S., Ricci, V., Foltran, L., Nicolini, M., Biondi, E. & 9 others, Bramati, A., Turci, D., Lazzarelli, S., Verusio, C., Bergamo, F., Sobrero, A., Frontini, L., Menghi, M. & Magnani, M., 2017, In : British Journal of Cancer. 117, 9, p. 1269-1277 9 p.

Research output: Contribution to journalArticle

FOLFOX4/XELOX in stage II–III colon cancer: Early survival data of the Italian three or six colon adjuvant (TOSCA) trial

Labianca, R., Mucciarini, C., Bidoli, P., Corsi, D., Montesarchio, V., Bochicchio Anna, M., Iaffaioli, V., Ciarlo, A., De Placido, S., Amoroso, D., Cortesi, E., Daniele, B., Amadori, D., Turci, D., Pelliccioni, S., Cinieri, S., Ravaioli, A., Piazza, E., Rulli, E. & Sobrero, A., Jun 2017, In : Annals of Oncology. 28, p. iii147

Research output: Contribution to journalArticle

Open Access

Maintenance therapy in advanced colorectal cancer, yes or no? Ask the laboratory

Sobrero, A. & Damiani, A., 2017, In : Annals of Oncology. 28, 9, p. 2043-2044 2 p.

Research output: Contribution to journalEditorial

Patient characteristics after completion of recruitment from the phase 3 IMPALA study with lefitolimod in metastatic colorectal carcinoma

Cunningham, D., Van Cutsem, E., Salazar, R., Ducreux, M., Scheithauer, W., Sclafani, F., Wiegert, E., Schmidt, M., Tournigand, C., Sobrero, A. & Arnold, D., Dec 2017, In : Annals of Oncology. 28, p. xi27

Research output: Contribution to journalArticle

Open Access

Phase III trial comparing 3-6 months of adjuvant FOLFOX4/XELOX in stage II-III colon cancer: safety and compliance in the TOSCA trial

Lonardi, S., Sobrero, A., Rosati, G., Di Bartolomeo, M., Ronzoni, M., Aprile, G., Massida, B., Scartozzi, M., Banzi, M., Zampino, M. G., Pasini, F., Marchetti, P., Cantore, M., Zaniboni, A., Rimassa, L., Ciuffreda, L., Ferrari, D., Barni, S., Zagonel, V., Maiello, E. & 3 others, Rulli, E., Labianca, R. & TOSCA (Three or Six Colon Adjuvant) Investigators, Feb 23 2017, In : Annals of Oncology.

Research output: Contribution to journalArticle

Prospective validation of a lymphocyte infiltration prognostic test in stage III colon cancer patients treated with adjuvant FOLFOX

Emile, J. F., Julié, C., Le Malicot, K., Lepage, C., Tabernero, J., Mini, E., Folprecht, G., Van Laethem, J. L., Dimet, S., Boulagnon-Rombi, C., Allard, M. A., Penault-Llorca, F., Bennouna, J., Laurent-Puig, P., Taieb, J., Thaler, J., Greil, R., Gaenzer, J., Eisterer, W., Tschmelitsch, J. & 320 others, Keil, F., Samonigg, H., Zabernigg, A., Schmid, F. X., Steger, G., Steinacher, R., Andel, J., Jagdt, B., Lang, A., Fridrik, M., Függer, R., Hofbauer, F., Woell, E., Geissler, D., Lenauer, A., Prager, M., D'Haens, G., Demolin, G., Kerger, J., Deboever, G., Ghillebert, G., Polus, M., Van Cutsem, E., Kalantari, H. R., Delaunoit, T., Goeminne, J. C., Peeters, M., Vergauwe, P., Houbiers, G., Humblet, Y., Janssens, J., Schrijvers, D., Vanderstraeten, E., Van Laethem, J. L., Vermorken, J., Van Daele, D., Ferrante, M., Forget, F., Hendlisz, A., Yilmaz, M., Nielsen, S. E., Vestermark, L., Larsen, J., Zawadi, M. A., Bouche, O., Mineur, L., Bennouna-Louridi, J., Dourthe, L. M., Ychou, M., Boucher, E., Taieb, J., Pezet, D., Desseigne, F., Ducreux, M., Texereau, P., Miglianico, L., Rougier, P., Fratte, S., Levache, C. B., Merrouche, Y., Ellis, S., Locher, C., Ramee, J. F., Garnier, C., Viret, F., Chauffert, B., Cojean-Zelek, I., Michel, P., Lecaille, C., Borel, J. C., Seitz, J. F., Smith, D., Lombard-Bohas, C., Andre, T., Gornet, J. M., Fein, F., Coulon-Sfairi, M. A., Kaminsky, M. C., Lagasse, J. P., Luet, D., Etienne, P. L., Gasmi, M., Vanoli, A., Nguyen, S., Aparicio, T., Perrier, H., Stremsdoerfer, N., Laplaige, P., Arsene, D., Auby, D., Bedenne, L., Coriat, R., Denis, B., Geoffroy, P., Piot, G., Becouarn, Y., Bordes, G., Deplanque, G., Dupuis, O., Fruge, F., Guimbaud, R., Lecomte, T., Lledo, G., Sobhani, I., Asnacios, A., Azzedine, A., Desauw, C., Galais, M. P., Gargot, D., Lam, Y. H., Abakar-Mahamat, A., Berdah, J. F., Catteau, S., Clavero-Fabri, M. C., Codoul, J. F., Legoux, J. L., Goldfain, D., Guichard, P., Verge, D. P., Provencal, J., Vedrenne, B., Brezault-Bonnet, C., Cleau, D., Desir, J. P., Fallik, D., Garcia, B., Gaspard, M. H., Genet, D., Hartwig, J., Krummel, Y., Budnik, T. M., Palascak-Juif, V., Randrianarivelo, H., Rinaldi, Y., Aleba, A., Darut-Jouve, A., de Gramont, A., Hamon, H., Wendehenne, F., Matzdorff, A., Stahl, M. K., Schepp, W., Burk, M., Mueller, L., Folprecht, G., Geissler, M., Mantovani-Loeffler, L., Hoehler, T., Asperger, W., Kroening, H., von Weikersthal, L. F., Fuxius, S., Groschek, M., Meiler, J., Trarbach, T., Rauh, J., Ziegenhagen, N., Kretzschmar, A., Graeven, U., Nusch, A., von Wichert, G., Hofheinz, R. D., Kleber, G., Schmidt, K. H., Vehling-Kaiser, U., Baum, C., Schuette, J., Haag, G. M., Holtkamp, W., Potenberg, J., Reiber, T., Schliesser, G., Schmoll, H-J., Schneider-Kappus, W., Abenhardt, W., Denzlinger, C., Henning, J., Marxsen, B., Derigs, H. G., Lambertz, H., Becker-Boost, I., Caca, K., Constantin, C., Decker, T., Eschenburg, H., Gabius, S., Hebart, H., Hoffmeister, A., Horst, H. A., Kremers, S., Leithaeuser, M., Mueller, S., Wagner, S., Daum, S., Schlegel, F., Stauch, M., Heinemann, V., Maiello, E., Latini, L., Zaniboni, A., Amadori, D., Aprile, G., Barni, S., Mattioli, R., Martoni, A., Passalacqua, R., Nicolini, M., Pasquini, E., Rabbi, C., Aitini, E., Ravaioli A., A., Barone, C., Biasco, G., Tamberi, S., Gambi, A., Verusio, C., Marzola, M., Lelli, G., Boni, C., Cascinu, S., Bidoli, P., Vaghi, M., Cruciani, G., Costanzo, F., Sobrero, A., Mini, E., Petrioli, R., Aglietta, M., Alabiso, O., Capuzzo, F., Falcone, A., Corsi, D. C., Labianca, R., Salvagni, S., Chiara, S., Ciuffreda, L., Ferraù, F., Giuliani, F., Lonardi, S., Gebbia, N., Mantovani, G., Sanches, E., Mellidez, J. C., Santos, P. G., Freire, J., Sarmento, C., Costa, J. L., Pinto, A. M., Barroso, S., Santo, J. E., Guedes, F., Monteiro, A., Sa, A., Furtado, I., Salazar, R., Aguilar, E. A., Herrero, F. R., Tabernero, J., Valera, J. S., Ayerbes, M. V., Batlle, J. F., Gil, S., Esteve, A. A., Garcia-Giron, C., Vivanco, G. L., Salvia, A. S., Orduña, V. A., Garcia, R. V., González-Gallego, J., Sureda, B. M., Remon, J., Safont Aguilera, M. J., Nogueras, L. C., Merino, B. Q., Castro, C. G., de Prado, P. M., Pericay, C. P., Figueiras, M. C., Jordan, I. G., Gome Reina, M. J., Garcia, A. L. L., Garcia-Ramos, A. A., Cervantes, A., Martos, C. F., Gaspar, E. M., Montero, I. C., Emperador, P. E., Carbonero, A. L., Castillo, M. G., Garcia, T. G., Lopez, J. G. S., Flores, E. G., Morales, M. G., Muñoz, M. L., Martín, A. L., Maurel, J., Camara, J. C., Garcia, R. D., Salgado, M., Busquier, I. H., Ruiz, T. C., Muñoa, A. L., Aliguer, M. N., de Taranco, A. V. O., Ureña, M. M., Gaspa, F. L., Ponce, J. J., Roig, C. B., Jimenez, P. V., Brotons, A. G., Rodriguez, S. A., Martinez, J. A., Ruiz, L. C., Ruiz, M. C., Bridgewater, J., Glynne-Jones, R., Tahir, S., Hickish, T., Cassidy, J. & Samuel, L., Sep 1 2017, In : European Journal of Cancer. 82, p. 16-24 9 p.

Research output: Contribution to journalArticle

The hard road to ranking the clinical benefit of antineoplastic agents: ESMO Award 2016 presentation

Sobrero, A., Apr 1 2017, In : ESMO Open. 2, 1, e000157.

Research output: Contribution to journalReview article

The urgent need to improve the tools to assess clinical benefit and value of cancer treatment

Sobrero, A., Puccini, A., Bregni, G. & Bruzzi, P., Sep 1 2017, In : European Journal of Cancer. 83, p. 324-328 5 p.

Research output: Contribution to journalArticle

2018

Aflibercept Plus FOLFIRI in the Real-life Setting: Safety and Quality of Life Data From the Italian Patient Cohort of the Aflibercept Safety and Quality-of-Life Program Study

Pastorino, A., Di Bartolomeo, M., Maiello, E., Iaffaioli, V., Ciuffreda, L., Fasola, G., Di Costanzo, F., Frassineti, G. L., Marchetti, P., Antoniotti, C., Leone, F., Zaniboni, A., Aprile, G., Zilocchi, C., Sobrero, A. & Bordonaro, R., Sep 1 2018, In : Clinical Colorectal Cancer. 17, 3, p. e457-e470

Research output: Contribution to journalArticle

Aflibercept Plus FOLFIRI in the Real-life Setting: Safety and Quality of Life Data From the Italian Patient Cohort of the Aflibercept Safety and Quality-of-Life Program Study

Pastorino, A., Di Bartolomeo, M., Maiello, E., Iaffaioli, V., Ciuffreda, L., Fasola, G., Di Costanzo, F., Frassineti, G. L., Marchetti, P., Antoniotti, C., Leone, F., Zaniboni, A., Aprile, G., Zilocchi, C., Sobrero, A. & Bordonaro, R., 2018, In : Clinical Colorectal Cancer. 17, 3, p. e457-e470

Research output: Contribution to journalArticle

Aflibercept Plus FOLFIRI in the Real-life Setting: Safety and Quality of Life Data From the Italian Patient Cohort of the Aflibercept Safety and Quality-of-Life Program Study

Pastorino, A., Di Bartolomeo, M., Maiello, E., Iaffaioli, V., Ciuffreda, L., Fasola, G., Di Costanzo, F., Frassineti, G. L., Marchetti, P., Antoniotti, C., Leone, F., Zaniboni, A., Aprile, G., Zilocchi, C., Sobrero, A. & Bordonaro, R., 2018, In : Clinical Colorectal Cancer. 17, 3, p. e457-e470

Research output: Contribution to journalArticle

Consensus statement on essential patient characteristics in systemic treatment trials for metastatic colorectal cancer: Supported by the ARCAD Group

Goey, K. K. H., Sørbye, H., Glimelius, B., Adams, R. A., André, T., Arnold, D., Berlin, J. D., Bodoky, G., de Gramont, A., Díaz-Rubio, E., Eng, C., Falcone, A., Grothey, A., Heinemann, V., Hochster, H. S., Kaplan, R. S., Kopetz, S., Labianca, R., Lieu, C. H., Meropol, N. J. & 12 others, Price, T. J., Schilsky, R. L., Schmoll, H. J., Shacham-Shmueli, E., Shi, Q., Sobrero, A. F., Souglakos, J., Van Cutsem, E., Zalcberg, J., van Oijen, M. G. H., Punt, C. J. A. & Koopman, M., Sep 1 2018, In : European Journal of Cancer. 100, p. 35-45 11 p.

Research output: Contribution to journalArticle

Duration of adjuvant chemotherapy for stage III colon cancer

Grothey, A., Sobrero, A. F., Shields, A. F., Yoshino, T., Paul, J., Taieb, J., Souglakos, J., Shi, Q., Kerr, R., Labianca, R., Meyerhardt, J. A., Vernerey, D., Yamanaka, T., Boukovinas, I., Meyers, J. P., Renfro, L. A., Niedzwiecki, D., Watanabe, T., Torri, V., Saunders, M. & 3 others, Sargent, D. J., Andre, T. & Iveson, T., Mar 29 2018, In : New England Journal of Medicine. 378, 13, p. 1177-1188 12 p.

Research output: Contribution to journalArticle

Efficacy and safety results from IMblaze370, a randomised Phase III study comparing atezolizumab+cobimetinib and atezolizumab monotherapy vs regorafenib in chemotherapy-refractory metastatic colorectal cancer

Bendell, J., Ciardiello, F., Tabernero, J., Tebbutt, N., Eng, C., Di Bartolomeo, M., Falcone, A., Fakih, M., Kozloff, M., Segal, N., Sobrero, A., Shi, Y., Roberts, L., Yan, Y., Chang, I., Uyei, A. & Kim, T., Jun 2018, In : Annals of Oncology. 29, p. v123

Research output: Contribution to journalArticle

Open Access

FOLFOX or CAPOX in stage II to III colon cancer: Efficacy results of the italian three or six colon adjuvant trial

on behalf of the TOSCA Investigators, May 20 2018, In : Journal of Clinical Oncology. 36, 15, p. 1478-1485 8 p.

Research output: Contribution to journalArticle

FOLFOX or CAPOX in stage II to III colon cancer: Efficacy Results of the Italian Three or Six Colon Adjuvant Trial

Investigators, O. B. O. T. TOSCA., Sobrero, A., Lonardi, S., Rosati, G., Di Bartolomeo, M., Ronzoni, M., Pella, N., Scartozzi, M., Banzi, M., Zampino, M. G., Pasini, F., Marchetti, P., Cantore, M., Zaniboni, A., Rimassa, L., Ciuffreda, L., Ferrari, D., Zagonel, V., Maiello, E., Barni, S. & 2 others, Rulli, E. & Labianca, R., May 20 2018, In : Journal of Clinical Oncology. 36, 15, p. 1478-1485 8 p.

Research output: Contribution to journalArticle

FOLFOX or CAPOX in stage II to III colon cancer: Efficacy results of the italian three or six colon adjuvant trial

Sobrero, A., Lonardi, S., Rosati, G., Di Bartolomeo, M., Ronzoni, M., Pella, N., Scartozzi, M., Banzi, M., Zampino, M. G., Pasini, F., Marchetti, P., Cantore, M., Zaniboni, A., Rimassa, L., Ciuffreda, L., Ferrari, D., Zagonel, V., Maiello, E., Barni, S., Rulli, E. & 1 others, Labianca, R., 2018, In : Journal of Clinical Oncology. 36, 15, p. 1478-1485 8 p.

Research output: Contribution to journalArticle

FOLFOX or CAPOX in stage II to III colon cancer: Efficacy results of the italian three or six colon adjuvant trial

Sobrero, A., Lonardi, S., Rosati, G., Di Bartolomeo, M., Ronzoni, M., Pella, N., Scartozzi, M., Banzi, M., Zampino, M. G., Pasini, F., Marchetti, P., Cantore, M., Zaniboni, A., Rimassa, L., Ciuffreda, L., Ferrari, D., Zagonel, V., Maiello, E., Barni, S., Rulli, E. & 1 others, Labianca, R., 2018, In : Journal of Clinical Oncology. 36, 15, p. 1478-1485 8 p.

Research output: Contribution to journalArticle

FOLFOX or CAPOX in Stage II to III Colon Cancer: Efficacy Results of the Italian Three or Six Colon Adjuvant Trial

Investigators, TOSCA., Sobrero, A., Lonardi, S., Rosati, G., Di Bartolomeo, M., Ronzoni, M., Pella, N., Scartozzi, M., Banzi, M., Zampino, M. G., Pasini, F., Marchetti, P., Cantore, M., Zaniboni, A., Rimassa, L., Ciuffreda, L., Ferrari, D., Zagonel, V., Maiello, E., Barni, S. & 2 others, Rulli, E. & Labianca, R., May 20 2018, In : Journal of Clinical Oncology. 36, 15, p. 1478-1485 8 p.

Research output: Contribution to journalArticle

Locoregional Tumor Therapy

Van Cutsem, E., Vogl, T. J., Orsi, F. & Sobrero, A., Jan 1 2018, Springer International Publishing AG. 274 p.

Research output: Book/ReportBook

Nintedanib for the treatment of patients with refractory metastatic colorectal cancer (LUME-Colon 1): A phase III, international, randomized, placebo-controlled study

Van Cutsem, E., Yoshino, T., Lenz, H. J., Lonardi, S., Falcone, A., Limón, M. L., Saunders, M., Sobrero, A., Park, Y. S., Ferreiro, R., Hong, Y. S., Tomasek, J., Taniguchi, H., Ciardiello, F., Stoehr, J., Oum'hamed, Z., Vlassak, S., Studeny, M. & Argiles, G., Sep 1 2018, In : Annals of Oncology. 29, 9, p. 1955-1963 9 p.

Research output: Contribution to journalArticle

Nintedanib for the treatment of patients with refractory metastatic colorectal cancer (LUME-Colon 1): A phase III, international, randomized, placebo-controlled study

Van Cutsem, E., Yoshino, T., Lenz, H. J., Lonardi, S., Falcone, A., Limón, M. L., Saunders, M., Sobrero, A., Park, Y. S., Ferreiro, R., Hong, Y. S., Tomasek, J., Taniguchi, H., Ciardiello, F., Stoehr, J., Oum'hamed, Z., Vlassak, S., Studeny, M. & Argiles, G., Sep 1 2018, In : Annals of Oncology. 29, 9, p. 1955-1963 9 p.

Research output: Contribution to journalArticle

Prognostic value of neutrophil-lymphocite ratio in resected high risk colorectal cancer: An analysis of adjuvant TOSCA trial

Petrelli, F., Rosati, G., Banzi, M., Zampino, M. G., Pella, N., Di Bartolomeo, M., Maiello, E., Bidoli, P., Ferrari, D., Rimassa, L., Labianca, R., Scartozzi, M., Lonardi, S., de Placido, S., Zaniboni, A., Sobrero, A., Frassineti, L. G., Silvestris, N., Corsi, D., Galli, F. & 1 others, Barni, S., Oct 1 2018, In : Annals of oncology : official journal of the European Society for Medical Oncology. 29, p. viii175

Research output: Contribution to journalArticle

Open Access

Regorafenib for Patients with Metastatic Colorectal Cancer Who Progressed After Standard Therapy: Results of the Large, Single-Arm, Open-Label Phase IIIb CONSIGN Study

Van Cutsem, E., Martinelli, E., Cascinu, S., Sobrero, A., Banzi, M., Seitz, J-F., Barone, C., Ychou, M., Peeters, M., Brenner, B., Hofheinz, R. D., Maiello, E., André, T., Spallanzani, A., Garcia-Carbonero, R., Arriaga, Y. E., Verma, U., Grothey, A., Kappeler, C., Miriyala, A. & 3 others, Kalmus, J., Falcone, A. & Zaniboni, A., Sep 6 2018, In : The oncologist.

Research output: Contribution to journalArticle

Regorafenib for Patients with Metastatic Colorectal Cancer Who Progressed After Standard Therapy: Results of the Large, Single-Arm, Open-Label Phase IIIb CONSIGN Study

Van Cutsem, E., Martinelli, E., Cascinu, S., Sobrero, A., Banzi, M., Seitz, J. F., Barone, C., Ychou, M., Peeters, M., Brenner, B., Hofheinz, R. D., Maiello, E., André, T., Spallanzani, A., Garcia-Carbonero, R., Arriaga, Y. E., Verma, U., Grothey, A., Kappeler, C., Miriyala, A. & 3 others, Kalmus, J., Falcone, A. & Zaniboni, A., Jan 1 2018, (Accepted/In press) In : Oncologist.

Research output: Contribution to journalArticle

Retrospective RAS analysis of the EPIC trial: Cetuximab plus irinotecan vs irinotecan in patients (pts) with second-line metastatic colorectal cancer (mCRC)

Sobrero, A., Lenz, H. J., Eng, C., Scheithauer, W., Middleton, G., Chen, W., Esser, R., Nippgen, J. & Burris, H., Oct 1 2018, In : Annals of oncology : official journal of the European Society for Medical Oncology. 29, p. viii163

Research output: Contribution to journalArticle

Open Access

Should oxaliplatin be added to 5FU-based regimens in adjuvant chemotherapy for locally advanced rectal cancer?

Sobrero, A. & Pastorino, A., Apr 6 2018, Multidisciplinary Management of Rectal Cancer: Questions and Answers. Springer International Publishing, p. 325-329 5 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

The hard road to data interpretation: 3 or 6 months of adjuvant chemotherapy for patients with stage III colon cancer?

Sobrero, A., Grothey, A., Iveson, T., Labianca, R., Yoshino, T., Taieb, J., Maughan, T., Buyse, M., André, T., Meyerhardt, J., Shields, A. F., Souglakos, I., Douillard, J. Y. & Cervantes, A., May 1 2018, In : Annals of Oncology. 29, 5, p. 1099-1107 9 p.

Research output: Contribution to journalArticle

Thromboembolic risk and survival with Khorana score in resected colorectal cancer patients: Subgroup analysis from the adjuvant TOSCA trial

Barni, S., Rosati, G., Zagonel, V., Pella, N., Banzi, M., Zampino, M. G., Di Bartolomeo, M., Rimassa, L., Marchetti, P., Maiello, E., Artioli, F., Ferrari, D., Labianca, R., Bidoli, P., Zaniboni, A., Sobrero, A., Iaffaioli, V., de Placido, S., Frassineti, L. G., Galli, F. & 1 others, Petrelli, F., Oct 1 2018, In : Annals of oncology : official journal of the European Society for Medical Oncology. 29, p. viii194-viii195

Research output: Contribution to journalArticle

Open Access
2019

Aflibercept Plus FOLFIRI for Second-line Treatment of Metastatic Colorectal Cancer: Observations from the Global Aflibercept Safety and Health-Related Quality-of-Life Program (ASQoP)

Riechelmann, R. P., Srimuninnimit, V., Bordonaro, R., Kavan, P., Di Bartolomeo, M., Maiello, E., Cicin, I., García-Alfonso, P., Chau, I., Fedyanin, M. Y., Martos, C. F., Ter-Ovanesov, M., Peeters, M., Ko, Y. J., Yalcin, S., Karthaus, M., Aparicio, J., Heinemann, V., Picard, P., Bury, D. & 2 others, Drea, E. & Sobrero, A., Sep 1 2019, In : Clinical Colorectal Cancer. 18, 3, p. 183-191.e3

Research output: Contribution to journalArticle

Open Access

Aflibercept Plus FOLFIRI for Second-line Treatment of Metastatic Colorectal Cancer: Observations from the Global Aflibercept Safety and Health-Related Quality-of-Life Program (ASQoP)

Riechelmann, R. P., Srimuninnimit, V., Bordonaro, R., Kavan, P., Di Bartolomeo, M., Maiello, E., Cicin, I., García-Alfonso, P., Chau, I., Fedyanin, M. Y., Martos, C. F., Ter-Ovanesov, M., Peeters, M., Ko, Y-J., Yalcin, S., Karthaus, M., Aparicio, J., Heinemann, V., Picard, P., Bury, D. & 2 others, Drea, E. & Sobrero, A., 2019, In : Clinical Colorectal Cancer. 18, 3, p. 183

Research output: Contribution to journalArticle

Aflibercept Plus FOLFIRI for Second-line Treatment of Metastatic Colorectal Cancer: Observations from the Global Aflibercept Safety and Health-Related Quality-of-Life Program (ASQoP): Clinical Colorectal Cancer

Riechelmann, R. P., Srimuninnimit, V., Bordonaro, R., Kavan, P., Di Bartolomeo, M., Maiello, E., Cicin, I., García-Alfonso, P., Chau, I., Fedyanin, M. Y., Martos, C. F., Ter-Ovanesov, M., Peeters, M., Ko, Y-J., Yalcin, S., Karthaus, M., Aparicio, J., Heinemann, V., Picard, P., Bury, D. & 2 others, Drea, E. & Sobrero, A., 2019, In : Clin Colorectal Cancer. 18, 3, p. 183

Research output: Contribution to journalArticle

Atezolizumab with or without cobimetinib versus regorafenib in previously treated metastatic colorectal cancer (IMblaze370): a multicentre, open-label, phase 3, randomised, controlled trial

Eng, C., Kim, T. W., Bendell, J., Argilés, G., Tebbutt, N. C., Di Bartolomeo, M., Falcone, A., Fakih, M., Kozloff, M., Segal, N. H., Sobrero, A., Yan, Y., Chang, I., Uyei, A., Roberts, L., Ciardiello, F., Ahn, J. B., Asselah, J., Badarinath, S., Baijal, S. & 30 others, Begbie, S., Berry, S., Canon, J. L., Carbone, R. G., Cervantes, A., Cha, Y. J., Chang, K., Chaudhry, A., Chmielowska, E., Cho, S. H., Chu, D., Couture, F., Cultrera, J., Cunningham, D., Van Cutsem, E., Cuyle, P. J., Davies, J., Dowden, S., Dvorkin, M., Ganju, V., Garcia, R. V., Kerr, R., Kim, T. Y., King, K., Kortmansky, J., Lam, K. O., Lee, J., Lee, A. S., Lesperance, B. & Maiello, E., 2019, In : The Lancet Oncology. 20, 6, p. 849-861 13 p.

Research output: Contribution to journalArticle

Health-related Quality of Life in the Phase III LUME-Colon 1 Study: Comparison and Interpretation of Results From EORTC QLQ-C30 Analyses

Lenz, H. J., Argiles, G., Yoshino, T., Lonardi, S., Falcone, A., Limón, M. L., Sobrero, A., Hastedt, C., Peil, B., Voss, F., Griebsch, I. & Van Cutsem, E., Dec 1 2019, In : Clinical Colorectal Cancer. 18, 4, p. 269-279.e 11 p.

Research output: Contribution to journalArticle

Open Access

Health-related Quality of Life in the Phase III LUME-Colon 1 Study: Comparison and Interpretation of Results From EORTC QLQ-C30 Analyses

Lenz, H. J., Argiles, G., Yoshino, T., Lonardi, S., Falcone, A., Limón, M. L., Sobrero, A., Hastedt, C., Peil, B., Voss, F., Griebsch, I. & Van Cutsem, E., Dec 1 2019, In : Clinical Colorectal Cancer. 18, 4, p. 269-279.e 10 p.

Research output: Contribution to journalArticle

HER2 Amplification and Anti-EGFR Sensitivity in Advanced Colorectal Cancer

Bregni, G., Sciallero, S. & Sobrero, A., May 1 2019, In : JAMA oncology. 5, 5, p. 605-606 2 p.

Research output: Contribution to journalComment/debate

Maximising clinical benefit with adequate patient management beyond the second line in mCRC

Argiles, G., Arnold, D., Prager, G., Sobrero, A. F. & Van Cutsem, E., May 1 2019, In : ESMO Open. 4, 2, e000495.

Research output: Contribution to journalReview article

Open Access

Real-world efficacy and safety of nivolumab in previously-treated metastatic renal cell carcinoma, and association between immune-related adverse events and survival: The Italian expanded access program

Verzoni, E., Cartenì, G., Cortesi, E., Giannarelli, D., De Giglio, A., Sabbatini, R., Buti, S., Rossetti, S., Cognetti, F., Rastelli, F., Sobrero, A., Turci, D., Sternberg, C. N., Porta, C., Cappuzzo, F., Tortora, G., Tassinari, D., Panni, S., Pazzola, A., Surico, G. & 3 others, Raimondi, A., De Giorgi, U. & Procopio, G., Apr 3 2019, In : Journal for ImmunoTherapy of Cancer. 7, 1, 99.

Research output: Contribution to journalArticle

Open Access

Real-world efficacy and safety of nivolumab in previously-treated metastatic renal cell carcinoma, and association between immune-related adverse events and survival: The Italian expanded access program

Verzoni, E., Cartenì, G., Cortesi, E., Giannarelli, D., De Giglio, A., Sabbatini, R., Buti, S., Rossetti, S., Cognetti, F., Rastelli, F., Sobrero, A., Turci, D., Sternberg, C. N., Porta, C., Cappuzzo, F., Tortora, G., Tassinari, D., Panni, S., Pazzola, A., Surico, G. & 3 others, Raimondi, A., De Giorgi, U. & Procopio, G., 2019, In : Journal for ImmunoTherapy of Cancer. 7, 1

Research output: Contribution to journalArticle

Real-world efficacy and safety of nivolumab in previously-treated metastatic renal cell carcinoma, and association between immune-related adverse events and survival: The Italian expanded access program

Verzoni, E., Cartenì, G., Cortesi, E., Giannarelli, D., De Giglio, A., Sabbatini, R., Buti, S., Rossetti, S., Cognetti, F., Rastelli, F., Sobrero, A., Turci, D., Sternberg, C. N., Porta, C., Cappuzzo, F., Tortora, G., Tassinari, D., Panni, S., Pazzola, A., Surico, G. & 3 others, Raimondi, A., De Giorgi, U. & Procopio, G., 2019, In : Journal for ImmunoTherapy of Cancer. 7, 1

Research output: Contribution to journalArticle

Safety and efficacy of nivolumab for metastatic renal cell carcinoma: real-world results from an expanded access programme

De Giorgi, U., Cartenì, G., Giannarelli, D., Basso, U., Galli, L., Cortesi, E., Caserta, C., Pignata, S., Sabbatini, R., Bearz, A., Buti, S., Lo Re, G., Berruti, A., Bracarda, S., Cognetti, F., Rastelli, F., Fornarini, G., Porta, C., Turci, D., Sternberg, C. N. & 81 others, Procopio, G., Falcone, A., Roila, F., Cascinu, S., Tirelli, U., Giustini, L., Sobrero, A., Cappuzzo, F., Tassinari, D., Passalacqua, R., Pazzola, A., Surico, G., Maio, M., Benedetti, G., Barone, C., Adamo, V., Ricevuto, E., De Censi, A., Spada, M., Tonini, G., Pinto, C., Ciuffreda, L., Ruggeri, E. M., Bengala, C., Scotti, V., Fagnani, D., Bonetti, A., Mitterer, M., Castiglione, F., Bidoli, P., Ferraù, F., Crinò, L., Frassoldati, A., Marchetti, P., Mini, E., Scoppola, A., Verusio, C., Favaretto, A., Di Costanzo, F., Fasola, G., Merlano, M., Artioli, F., Di Leo, A., Romito, S., Maestri, A., Giannitto Giorgio, C., Ionta, M. T., Verderame, F., Zampa, G., Numico, G., Minelli, M., Tagliaferri, P., Foa, P., Palmiotti, G., De Placido, S., Mattioli, R., Iuliano, F., Defraia, E., Siena, S., Clerico, M., Salvagno, L., Ceresoli, G. L., Bernardo, A., Di Lieto, M., Moroni, M., Maisano, M., Scartozzi, M., Scagliotti, G., Sorarù, M., Pepe, S., Scaltriti, A., Gebbia, V., Testa, E., Lorusso, V., Bordonaro, R., De Signoribus, G., Tedde, N., Santoro, A., Francini, G., Aondio, G. & Group, T. I. N. R. C. C. E. A. P., 2019, In : BJU International. 123, 1, p. 98-105 8 p.

Research output: Contribution to journalArticle

Safety and efficacy of nivolumab for metastatic renal cell carcinoma: real-world results from an expanded access programme

De Giorgi, U., Cartenì, G., Giannarelli, D., Basso, U., Galli, L., Cortesi, E., Caserta, C., Pignata, S., Sabbatini, R., Bearz, A., Buti, S., Lo Re, G., Berruti, A., Bracarda, S., Cognetti, F., Rastelli, F., Fornarini, G., Porta, C., Turci, D., Sternberg, C. N. & 30 others, Procopio, G., Falcone, A., Roila, F., Cascinu, S., Tirelli, U., Giustini, L., Sobrero, A., Cappuzzo, F., Tassinari, D., Passalacqua, R., Pazzola, A., Surico, G., Maio, M., Benedetti, G., Barone, C., Spada, M., Tonini, G., Pinto, C., Ciuffreda, L., Scotti, V., Crinò, L., Marchetti, P., Scoppola, A., Favaretto, A., Mattioli, R., Bernardo, A., Di Lieto, M., Moroni, M., Lorusso, V. & Santoro, A., 2019, In : BJU International. 123, 1, p. 98-105 8 p.

Research output: Contribution to journalArticle

Safety and efficacy of nivolumab for metastatic renal cell carcinoma: real-world results from an expanded access programme: BJU International

De Giorgi, U., Cartenì, G., Giannarelli, D., Basso, U., Galli, L., Cortesi, E., Caserta, C., Pignata, S., Sabbatini, R., Bearz, A., Buti, S., Lo Re, G., Berruti, A., Bracarda, S., Cognetti, F., Rastelli, F., Fornarini, G., Porta, C., Turci, D., Sternberg, C. N. & 81 others, Procopio, G., Falcone, A., Roila, F., Cascinu, S., Tirelli, U., Giustini, L., Sobrero, A., Cappuzzo, F., Tassinari, D., Passalacqua, R., Pazzola, A., Surico, G., Maio, M., Benedetti, G., Barone, C., Adamo, V., Ricevuto, E., De Censi, A., Spada, M., Tonini, G., Pinto, C., Ciuffreda, L., Ruggeri, E. M., Bengala, C., Scotti, V., Fagnani, D., Bonetti, A., Mitterer, M., Castiglione, F., Bidoli, P., Ferraù, F., Crinò, L., Frassoldati, A., Marchetti, P., Mini, E., Scoppola, A., Verusio, C., Favaretto, A., Di Costanzo, F., Fasola, G., Merlano, M., Artioli, F., Di Leo, A., Romito, S., Maestri, A., Giannitto Giorgio, C., Ionta, M. T., Verderame, F., Zampa, G., Numico, G., Minelli, M., Tagliaferri, P., Foa, P., Palmiotti, G., De Placido, S., Mattioli, R., Iuliano, F., Defraia, E., Siena, S., Clerico, M., Salvagno, L., Ceresoli, G. L., Bernardo, A., Di Lieto, M., Moroni, M., Maisano, M., Scartozzi, M., Scagliotti, G., Sorarù, M., Pepe, S., Scaltriti, A., Gebbia, V., Testa, E., Lorusso, V., Bordonaro, R., De Signoribus, G., Tedde, N., Santoro, A., Francini, G., Aondio, G. & Group, T. I. N. R. C. C. E. A. P., 2019, In : HSB International. 123, 1, p. 98-105 8 p.

Research output: Contribution to journalArticle

Sex-Related Differences in Impact on Safety of Pharmacogenetic Profile for Colon Cancer Patients Treated with FOLFOX-4 or XELOX Adjuvant Chemotherapy

Ruzzo, A., Graziano, F., Galli, F., Galli, F., Rulli, E., Lonardi, S., Ronzoni, M., Massidda, B., Zagonel, V., Pella, N., Mucciarini, C., Labianca, R., Ionta, M. T., Bagaloni, I., Veltri, E., Sozzi, P., Barni, S., Ricci, V., Foltran, L., Nicolini, M. & 9 others, Biondi, E., Bramati, A., Turci, D., Lazzarelli, S., Verusio, C., Bergamo, F., Sobrero, A., Frontini, L. & Magnani, M., Dec 1 2019, In : Scientific Reports. 9, 1, 11527.

Research output: Contribution to journalArticle

Open Access

Sex-Related Differences in Impact on Safety of Pharmacogenetic Profile for Colon Cancer Patients Treated with FOLFOX-4 or XELOX Adjuvant Chemotherapy

Ruzzo, A., Graziano, F., Galli, F., Galli, F., Rulli, E., Lonardi, S., Ronzoni, M., Massidda, B., Zagonel, V., Pella, N., Mucciarini, C., Labianca, R., Ionta, M. T., Bagaloni, I., Veltri, E., Sozzi, P., Barni, S., Ricci, V., Foltran, L., Nicolini, M. & 9 others, Biondi, E., Bramati, A., Turci, D., Lazzarelli, S., Verusio, C., Bergamo, F., Sobrero, A., Frontini, L. & Magnani, M., Aug 8 2019, In : Sci. Rep.. 9, 1, p. 1-9 9 p., 11527.

Research output: Contribution to journalArticle