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Research Output

Sequence-dependent synergism between dichloromethotrexate and 5-fluorouracil in a human colon carcinoma cell line

Sobrero, A. F. & Bertino, J. R., 1983, In : Cancer Research. 43, 9, p. 4011-4013 3 p.

Research output: Contribution to journalArticle

Sequence-dependent synergism between dichloromethotrexate and cisplatin in a human colon carcinoma cell line

Sobrero, A. F. & Bertino, J. R., 1985, In : Cancer Treatment Reports. 69, 3, p. 279-283 5 p.

Research output: Contribution to journalArticle

Sequential chemotherapy with paclitaxel plus cisplatin, followed by vinorelbine, followed by gemcitabine in advanced non-small cell lung cancer: An Alpe-Adria Thoracic Oncology Multidisciplinary group study (ATOM 001)

Grossi, F., Belvedere, O., Fasola, G., Barbone, F., Rizzato, S., Sibau, A., Recchia, L., Vigevani, E., Ceschia, T., Morelli, A., Guglielmi, A., Puglisi, F., Follador, A., Talmassons, G. & Sobrero, A. F., Oct 2004, In : Lung Cancer. 46, 1, p. 99-106 8 p.

Research output: Contribution to journalArticle

Sex-Related Differences in Impact on Safety of Pharmacogenetic Profile for Colon Cancer Patients Treated with FOLFOX-4 or XELOX Adjuvant Chemotherapy

Ruzzo, A., Graziano, F., Galli, F., Galli, F., Rulli, E., Lonardi, S., Ronzoni, M., Massidda, B., Zagonel, V., Pella, N., Mucciarini, C., Labianca, R., Ionta, M. T., Bagaloni, I., Veltri, E., Sozzi, P., Barni, S., Ricci, V., Foltran, L., Nicolini, M. & 9 others, Biondi, E., Bramati, A., Turci, D., Lazzarelli, S., Verusio, C., Bergamo, F., Sobrero, A., Frontini, L. & Magnani, M., Dec 1 2019, In : Scientific Reports. 9, 1, 11527.

Research output: Contribution to journalArticle

Open Access

Sex-Related Differences in Impact on Safety of Pharmacogenetic Profile for Colon Cancer Patients Treated with FOLFOX-4 or XELOX Adjuvant Chemotherapy

Ruzzo, A., Graziano, F., Galli, F., Galli, F., Rulli, E., Lonardi, S., Ronzoni, M., Massidda, B., Zagonel, V., Pella, N., Mucciarini, C., Labianca, R., Ionta, M. T., Bagaloni, I., Veltri, E., Sozzi, P., Barni, S., Ricci, V., Foltran, L., Nicolini, M. & 9 others, Biondi, E., Bramati, A., Turci, D., Lazzarelli, S., Verusio, C., Bergamo, F., Sobrero, A., Frontini, L. & Magnani, M., Aug 8 2019, In : Sci. Rep.. 9, 1, p. 1-9 9 p., 11527.

Research output: Contribution to journalArticle

Should adjuvant chemotherapy become standard treatment for patients with stage II colon cancer?

Sobrero, A. & Köhne, C. H., Jun 2006, In : The Lancet Oncology. 7, 6, p. 515-517 3 p.

Research output: Contribution to journalArticle

Should oxaliplatin be added to 5FU-based regimens in adjuvant chemotherapy for locally advanced rectal cancer?

Sobrero, A. & Pastorino, A., Apr 6 2018, Multidisciplinary Management of Rectal Cancer: Questions and Answers. Springer International Publishing, p. 325-329 5 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Small molecule inhibitors of tyrosine kinase: Waiting for the good news in colorectal cancer as well

Sobrero, A. & Andretta, V., May 2008, In : Onkologie. 31, 5, p. 224-225 2 p.

Research output: Contribution to journalArticle

SOMMINISTRAZIONE ALTERNA DI METOTREXATE E TRIMETREXATE: RIDUZIONE DEL GRADO DI RESISTENZA AGLI ANTIFOLATI IN VITRO

Translated title of the contribution: Alternating trimetrexate with methotrexate reduces the degree of resistance to antifolates in vitroAschele, C., Maioli, D., Gamba, E., Romanini, A., Vidili, M. G., Nob ile, M. T., Nicolin, A., Rosso, R. & Sobrero, A., 1989, In : Folia Oncologica. 12, 2, p. 95-100 6 p.

Research output: Contribution to journalArticle

Sorafenib does not improve efficacy of chemotherapy in advanced pancreatic cancer: A GISCAD randomized phase II study

Cascinu, S., Berardi, R., Sobrero, A., Bidoli, P., Labianca, R., Siena, S., Ferrari, D., Barni, S., Aitini, E., Zagonel, V., Caprioni, F., Villa, F., Mosconi, S., Faloppi, L., Tonini, G., Boni, C., Conte, P., Di Costanzo, F. & Cinquini, M., Feb 2014, In : Digestive and Liver Disease. 46, 2, p. 182-186 5 p.

Research output: Contribution to journalArticle

Sorafenib in combination with oxaliplatin, leucovorin, and fluorouracil (modified FOLFOX6) as first-line treatment of metastatic colorectal cancer: The RESPECT trial

Tabernero, J., Garcia-Carbonero, R., Cassidy, J., Sobrero, A., Van Cutsem, E., Köhne, C. H., Tejpar, S., Gladkov, O., Davidenko, I., Salazar, R., Vladimirova, L., Cheporov, S., Burdaeva, O., Rivera, F., Samuel, L., Bulavina, I., Potter, V., Chang, Y. L., Lokker, N. A. & O'Dwyer, P. J., May 1 2013, In : Clinical Cancer Research. 19, 9, p. 2541-2550 10 p.

Research output: Contribution to journalArticle

Standard indication of immunotherapy for the treatnent of cancer

Boli, E., Tina, L., Wbri, A., Gugielmi, A., Awhele, C., Wviru, E. & Sobrero, A., 1992, In : Pharmacological Research. 26, SUPPL. 2, p. 100-101 2 p.

Research output: Contribution to journalArticle

State of the art: Colorectal liver metastases

Sobrero, A. & Pastorino, A., Nov 1 2014, In : Future Oncology. 10, p. 29-32 4 p.

Research output: Contribution to journalArticle

Studies on hemopoietic stem cells in mice treated with testosterone propionate and anticancer drugs

Bogliolo, G., Massa, G., Sobrero, A. & Pannacciulli, I., 1982, In : Tumori. 68, 4, p. 277-282 6 p.

Research output: Contribution to journalArticle

Synergism and lack of cross-resistance between short-term and continuous exposure to fluorouracil in human colon adenocarcinoma cells

Sobrero, A. F., Aschele, C., Guglielmi, A. P., Mori, A. M., Melioli, G. G., Rosso, R. & Bertino, J. R., 1993, In : Journal of the National Cancer Institute. 85, 23, p. 1937-1944 8 p.

Research output: Contribution to journalArticle

Talking 'Tomudex': introduction.

Sobrero, A., Aug 1997, In : Anti-Cancer Drugs. 8 Suppl 2

Research output: Contribution to journalArticle

Talking 'Tomudex' Madrid, 19 April 1997. Introduction

Sobrero, A., 1997, In : Anti-Cancer Drugs. 8, SUPPL. 2

Research output: Contribution to journalArticle

Tamoxifen-induced total alopecia [5]

Puglisi, F., Aprile, G. & Sobrero, A., Jun 19 2001, In : Annals of Internal Medicine. 134, 12, p. 1154-1155 2 p.

Research output: Contribution to journalArticle

TAS-102 in refractory colorectal cancer: Caution is needed

Sobrero, A., Oct 2012, In : The Lancet Oncology. 13, 10, p. 959-961 3 p.

Research output: Contribution to journalArticle

Taxane-induced nail changes: Incidence, clinical presentation and outcome

Minisini, A. M., Tosti, A., Sobrero, A. F., Mansutti, M., Piraccini, B. M., Sacco, C. & Puglisi, F., Feb 1 2003, In : Annals of Oncology. 14, 2, p. 333-337 5 p.

Research output: Contribution to journalArticle

The diagnosis and management of gastric cancer: Expert discussion and recommendations from the 12th ESMO/World Congress on Gastrointestinal Cancer, Barcelona, 2010

van Cutsem, E., Dicato, M., Geva, R., Arber, N., Bang, Y., Benson, A., Cervantes, A., Diaz-Rubio, E., Ducreux, M., Glynne-Jones, R., Grothey, A., Haller, D., Haustermans, K., Kerr, D., Nordlinger, B., Marshall, J., Minsky, B. D., Kang, Y. K., Labianca, R., Lordick, F. & 9 others, Ohtsu, A., Pavlidis, N., Roth, A., Rougier, P., Schmoll, H. J., Sobrero, A., Tabernero, J., van de Velde, C. & Zalcberg, J., 2011, In : Annals of Oncology. 22, SUPPL. 5

Research output: Contribution to journalArticle

The diagnosis and management of rectal cancer: Expert discussion and recommendations derived from the 9th world congress on gastrointestinal cancer, Barcelona, 2007

Van Cutsem, E., Dicato, M., Haustermans, K., Arber, N., Bosset, J. F., Cunningham, D., De Gramont, A., Diaz-Rubio, E., Ducreux, M., Goldberg, R., Glynne-Jones, R., Haller, D., Kang, Y. K., Kerr, D., Labianca, R., Minsky, B. D., Moore, M., Nordlinger, B., Rougier, P., Scheithauer, W. & 6 others, Schmoll, H. J., Sobrero, A., Tabernero, J., Tempero, M., Van de Velde, C. & Zalcberg, J., Jun 2008, In : Annals of Oncology. 19, SUPPL. 6

Research output: Contribution to journalArticle

The handling of metastatic colorectal cancer

Fornarini, G., Guglielmi, A. & Sobrero, A., 2005, In : Annals of Oncology. 16, SUPPL. 2

Research output: Contribution to journalArticle

The hard road to data interpretation: 3 or 6 months of adjuvant chemotherapy for patients with stage III colon cancer?

Sobrero, A., Grothey, A., Iveson, T., Labianca, R., Yoshino, T., Taieb, J., Maughan, T., Buyse, M., André, T., Meyerhardt, J., Shields, A. F., Souglakos, I., Douillard, J. Y. & Cervantes, A., May 1 2018, In : Annals of Oncology. 29, 5, p. 1099-1107 9 p.

Research output: Contribution to journalArticle

The hard road to ranking the clinical benefit of antineoplastic agents: ESMO Award 2016 presentation

Sobrero, A., Apr 1 2017, In : ESMO Open. 2, 1, e000157.

Research output: Contribution to journalReview article

The IDEA (international duration evaluation of adjuvant chemotherapy) collaboration: Prospective combined analysis of phase III trials investigating duration of adjuvant therapy with the FOLFOX (FOLFOX4 or modified FOLFOX6) or XELOX (3 versus 6 months) regimen for patients with stage III colon cancer: Trial design and current status

André, T., Iveson, T., Labianca, R., Meyerhardt, J. A., Souglakos, I., Yoshino, T., Paul, J., Sobrero, A., Taieb, J., Shields, A. F., Ohtsu, A., Grothey, A. & Sargent, D. J., Sep 2013, In : Current Colorectal Cancer Reports. 9, 3, p. 261-269 9 p.

Research output: Contribution to journalArticle

The management of hepatocellular carcinoma. Current expert opinion and recommendations derived from the 10th World Congress on Gastrointestinal Cancer, Barcelona, 2008

Verslype, C., Van Cutsem, E., Dicato, M., Arber, N., Berlin, J. D., Cunningham, D., De Gramont, A., Diaz-Rubio, E., Ducreux, M., Gruenberger, T., Haller, D., Haustermans, K., Hoff, P., Kerr, D., Labianca, R., Moore, M., Nordlinger, B., Ohtsu, A., Rougier, P., Scheithauer, W. & 4 others, Schmoll, H. J., Sobrero, A., Tabernero, J. & van de Velde, C., 2009, In : Annals of Oncology. 20, SUPPL.7, p. 1-6 6 p.

Research output: Contribution to journalArticle

The management of skin reactions in cancer patients receiving epidermal growth factor receptor targeted therapies

Segaert, S., Tabernero, J., Chosidow, O., Dirschka, T., Elsner, J., Mancini, L., Maughan, T., Morere, J. F., Santoro, A., Sobrero, A., Van Cutsem, E. & Layton, A., Aug 2005, In : JDDG - Journal of the German Society of Dermatology. 3, 8, p. 599-606 8 p.

Research output: Contribution to journalArticle

The need for a new fluoropyrimidine in advanced gastric cancer treatment

Van Cutsem, E., Haller, D. G., Sobrero, A., Yamada, Y., Douillard, J. Y. & Moehler, M., Nov 2012, In : European Oncology and Haematology. 8, 4, p. 232-240 9 p.

Research output: Contribution to journalArticle

The neo-adjuvant, surgical and adjuvant treatment of gastric adenocarcinoma. Current expert opinion derived from the Seventh World Congress on Gastrointestinal Cancer, Barcelona, 2005

Van Cutsem, E., Dicato, M., Arber, N., Benson, A., Cunningham, D., Diaz-Rubio, E., Glimelius, B., Goldberg, R., Haller, D., Haustermans, K., Koo-Kang, Y., Labianca, R., Lang, I., Minsky, B., Nordlinger, B., Roth, A., Rougier, P., Schmoll, H. J., Sobrero, A., Tabernero, J. & 2 others, Szawlowski, A. & van de Velde, C., Jun 2006, In : Annals of Oncology. 17, SUPPL. 6

Research output: Contribution to journalArticle

The oncosurgery approach to managing liver metastases from colorectal cancer: A multidisciplinary international consensus

Adam, R., De Gramont, A., Figueras, J., Guthrie, A., Kokudo, N., Kunstlinger, F., Loyer, E., Poston, G., Rougier, P., Rubbia-Brandt, L., Sobrero, A., Tabernero, J., Teh, C., Van Cutsem, E. & Vauthey, J. N., 2012, In : The oncologist. 17, 10, p. 1225-1239 15 p.

Research output: Contribution to journalArticle

The Optimal Duration of Adjuvant Therapy for Stage III Colon Cancer: the European Perspective

Bregni, G., Rebuzzi, S. E. & Sobrero, A., Jan 1 2019, In : Current Treatment Options in Oncology. 20, 1, 8.

Research output: Contribution to journalReview article

The potential role of tomudex in the treatment of advanced colorectal cancer

Sobrero, A. F., Mar 1997, In : Tumori. 83, 2, p. 576-580 5 p.

Research output: Contribution to journalArticle

The role of 5-fluorouracil (5-FU) reintroduction with irinotecan or oxaliplatin in truly 5-FU-refractory advanced colorectal cancer patients

Scartozzi, M., Sobrero, A., Gasparini, G., Berardi, R., Catalano, V., Graziano, F., Barni, S., Zaniboni, A., Beretta, G. D., Labianca, R. & Cascinu, S., Jul 2005, In : Oncology. 68, 2-3, p. 212-216 5 p.

Research output: Contribution to journalArticle

The role of methotrexate in the chemotherapy of gestational trophoblastic neoplasms.

Sobrero, A. & Bertino, J. R., 1984, In : Advances in Experimental Medicine and Biology. 176, p. 343-354 12 p.

Research output: Contribution to journalArticle

The two sides of 5-fluorouracil: Bolus and continuous infusion

Aschele, C., Guglielmi, A., Mori, A., Tixi, L., Bolli, E., Ciferri, E., Fazio, S., Municino, O. & Sobrero, A., 1995, In : Journal of Experimental and Clinical Cancer Research. 14, 2 SUPPL., p. 53-59 7 p.

Research output: Contribution to journalArticle

The urgent need to improve the tools to assess clinical benefit and value of cancer treatment

Sobrero, A., Puccini, A., Bregni, G. & Bruzzi, P., Sep 1 2017, In : European Journal of Cancer. 83, p. 324-328 5 p.

Research output: Contribution to journalArticle

The value of lactate dehydrogenase serum levels as a prognostic and predictive factor for advanced pancreatic cancer patients receiving sorafenib

Faloppi, L., Bianconi, M., Giampieri, R., Sobrero, A., Labianca, R., Ferrari, D., Barni, S., Aitini, E., Zaniboni, A., Boni, C., Caprioni, F., Mosconi, S., Fanello, S., Berardi, R., Bittoni, A., Andrikou, K., Cinquini, M., Torri, V., Scartozzi, M. & Cascinu, S., 2015, In : Oncotarget. 6, 33, p. 35087-35094 8 p.

Research output: Contribution to journalArticle

Thromboembolic risk and survival with Khorana score in resected colorectal cancer patients: Subgroup analysis from the adjuvant TOSCA trial

Barni, S., Rosati, G., Zagonel, V., Pella, N., Banzi, M., Zampino, M. G., Di Bartolomeo, M., Rimassa, L., Marchetti, P., Maiello, E., Artioli, F., Ferrari, D., Labianca, R., Bidoli, P., Zaniboni, A., Sobrero, A., Iaffaioli, V., de Placido, S., Frassineti, L. G., Galli, F. & 1 others, Petrelli, F., Oct 1 2018, In : Annals of oncology : official journal of the European Society for Medical Oncology. 29, p. viii194-viii195

Research output: Contribution to journalArticle

Open Access

Time-dependent interactions between 5-fluorouracil and mitomycin C on a human colon carcinoma cell line, HCT-8, in vitro

Russello, O., Romanini, A., Civalleri, D., Rosso, R., Nicolin, A. & Sobrero, A., 1989, In : European Journal of Cancer and Clinical Oncology. 25, 3, p. 571-572 2 p.

Research output: Contribution to journalArticle

Time required to start multicentre clinical trials within the Italian Medicine Agency programme of support for independent research

De Feo, G., Frontini, L., Rota, S., Pepe, A., Signoriello, S., Labianca, R., Sobrero, A., De Placido, S. & Perrone, F., 2015, In : Journal of Medical Ethics. 41, 10, p. 799-803 5 p.

Research output: Contribution to journalArticle

Trattamento adiuvante del carcinoma del colon. Stato dell'arte e prospettive future.

Translated title of the contribution: Adjuvant therapy of colon cancer. State of the art and future perspectivesBarni, S., Cascinu, S., Foa, P., Frontini, L., Labianca, R., Luporini, G., Mandalà, M., Martignoni, G., Pancera, G., Sobrero, A. & Zaniboni, A., May 1999, In : Tumori. 85, 3

Research output: Contribution to journalArticle

TRATTAMENTO SEQUENZIALE CON METHOTREXATE 5-FLUOROURACILE + ACIDO FOLIN ICO IN PAZIENTI CON CARCINOMA DEL COLON RETTO RESISTENTI AL5-FLUOROURACILE

Translated title of the contribution: Sequential therapy with methotrexate and 5-fluorouracil in combination with folinic acid in advanced colorectal carcinomaVidili, M. G., Nobile, M. T., Aschele, C., Guglielmi Venturini, A. M., Sobrero, A. & Rosso, R., 1989, In : Folia Oncologica. 12, 3, p. 173-175 3 p.

Research output: Contribution to journalArticle

Tumor measurements on computed tomographic images of non-small cell lung cancer were similar among cancer professionals from different specialties

Grossi, F., Belvedere, O., Fasola, G., Ceschia, T., Meduri, S., Sibau, A., Sacco, C., Bazzocchi, M., Talmassons, G., Morelli, A., Barbone, F. & Sobrero, A., Aug 2004, In : Journal of Clinical Epidemiology. 57, 8, p. 804-808 5 p.

Research output: Contribution to journalArticle