• 2791 Citations
  • 23 h-Index
19972018
If you made any changes in Pure these will be visible here soon.

Fingerprint Dive into the research topics where Alessandra Boletta is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 3 Similar Profiles
Autosomal Dominant Polycystic Kidney Medicine & Life Sciences
Polycystic Kidney Diseases Medicine & Life Sciences
Kidney Medicine & Life Sciences
Cilia Medicine & Life Sciences
Cysts Medicine & Life Sciences
Genes Medicine & Life Sciences
TRPP Cation Channels Medicine & Life Sciences
Madin Darby Canine Kidney Cells Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Research Output 1997 2018

  • 2791 Citations
  • 23 h-Index
  • 45 Article

Casein kinase 1ε and 1α as novel players in polycystic kidney disease and mechanistic targets for (R)-roscovitine and (S)-CR8

Billot, K., Coquil, C., Villiers, B., Josselin-Foll, B., Desban, N., Delehouzé, C., Oumata, N., Meur, YL., Boletta, A., Weimbs, T., Grosch, M., Witzgall, R., Saunier, S., Fischer, E., Pontoglio, M., Fautrel, A., Mrug, M., Wallace, D., Tran, PV., Trudel, M. & 3 others, Bukanov, N., Ibraghimov-Beskrovnaya, O. & Meijer, L., 2018, In : American Journal of Physiology - Renal Physiology. 315, 1, p. F57-F73

Research output: Contribution to journalArticle

Casein Kinase I
Polycystic Kidney Diseases
Cyclin-Dependent Kinases
roscovitine
Affinity Chromatography

Metabolism and mitochondria in polycystic kidney disease research and therapy

Padovano, V., Podrini, C., Boletta, A. & Caplan, MJ., 2018, In : Nature Reviews Nephrology. 14, p. 678-687 10 p.

Research output: Contribution to journalArticle

Autosomal Dominant Polycystic Kidney
Polycystic Kidney Diseases
Mitochondria
TRPP Cation Channels
Research

mTORC1 Upregulation Leads to Accumulation of the Oncometabolite Fumarate in a Mouse Model of Renal Cell Carcinoma

Drusian, L., Nigro, EA., Mannella, V., Pagliarini, R., Pema, M., Costa, ASH., Benigni, F., Larcher, A., Chiaravalli, M., Gaude, E., Montorsi, F., Capitanio, U., Musco, G., Frezza, C. & Boletta, A., 2018, In : Cell Reports. 24, 5, p. 1093-1104.e6

Research output: Contribution to journalArticle

Fumarates
Renal Cell Carcinoma
Fumarate Hydratase
Up-Regulation
Cells
8 Citations (Scopus)

Defective glycolysis and the use of 2-deoxy-d-glucose in polycystic kidney disease: from animal models to humans

Magistroni, R. & Boletta, A., 2017, In : Journal of Nephrology. 30, 4, p. 511-519 9 p.

Research output: Contribution to journalArticle

Autosomal Dominant Polycystic Kidney
Polycystic Kidney Diseases
Glycolysis
Animal Models
Glucose
8 Citations (Scopus)

Double inhibition of cAMP and mTOR signalling may potentiate the reduction of cell growth in ADPKD cells

de Stephanis, L., Bonon, A., Varani, K., Lanza, G., Gafà, R., Pinton, P., Pema, M., Somlo, S., Boletta, A. & Aguiari, G., 2017, In : Clinical and Experimental Nephrology. 21, 2, p. 203-211 9 p.

Research output: Contribution to journalArticle

Autosomal Dominant Polycystic Kidney
Growth
Kidney
Sirolimus
Cell Proliferation