• 214 Citations
  • 7 h-Index
20132019
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Research Output 2013 2019

  • 214 Citations
  • 7 h-Index
  • 15 Article
  • 1 Review article
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Article
2019

LAV-BPIFB4 associates with reduced frailty in humans and its transfer prevents frailty progression in old mice

Malavolta, M., Dato, S., Villa, F., De Rango, F., Iannone, F., Ferrario, A., Maciag, A., Ciaglia, E., D'amato, A., Carrizzo, A., Basso, A., Orlando, F., Provinciali, M., Madeddu, P., Passarino, G., Vecchione, C., Rose, G. & Puca, A. A., Jan 1 2019, In : Aging. 11, 16, p. 6555-6568 14 p.

Research output: Contribution to journalArticle

Open Access
Haplotypes
Genes
Life Expectancy
Genetic Markers
Italy

Single systemic transfer of a human gene associated with exceptional longevity halts the progression of atherosclerosis and inflammation in ApoE knockout mice through a CXCR4-mediated mechanism

Puca, A. A., Carrizzo, A., Spinelli, C., Damato, A., Ambrosio, M., Villa, F., Ferrario, A., Maciag, A., Fornai, F., Lenzi, P., Valenti, V., di Nonno, F., Accarino, G., Madonna, M., Forte, M., Calì, G., Baragetti, A., Norata, G. D., Catapano, A. L., Cattaneo, M. & 10 others, Izzo, R., Trimarco, V., Montella, F., Versaci, F., Auricchio, A., Frati, G., Sciarretta, S., Madeddu, P., Ciaglia, E. & Vecchione, C., Jul 10 2019, In : European Heart Journal.

Research output: Contribution to journalArticle

CXCR4 Receptors
Apolipoproteins E
Knockout Mice
Atherosclerosis
Inflammation

Association of immunoglobulin GM allotypes with longevity in long-living individuals from Southern Italy

Puca, A. A., Ferrario, A., Maciag, A., Accardi, G., Aiello, A., Gambino, C. M., Candore, G., Caruso, C., Namboodiri, A. M. & Pandey, J. P., 2018, In : Immunity and Ageing. 15, p. 26

Research output: Contribution to journalArticle

Immunoglobulin Allotypes
Italy
Alleles
Chi-Square Distribution
Immunoglobulin Subunits
2017

A rare genetic variant of BPIFB4 predisposes to high blood pressure via impairment of nitric oxide signaling

Vecchione, C., Villa, F., Carrizzo, A., Spinelli, C. C., Damato, A., Ambrosio, M., Ferrario, A., Madonna, M., Uccellatore, A., Lupini, S., Maciag, A., Ryskalin, L., Milanesi, L., Frati, G., Sciarretta, S., Bellazzi, R., Genovese, S., Ceriello, A., Auricchio, A., Malovini, A. & 1 others, Puca, A. A., Aug 29 2017, In : Scientific Reports. 7, 1, p. 9706

Research output: Contribution to journalArticle

Nitric Oxide
Blood Pressure
Hypertension
Nitric Oxide Synthase Type III
Gene Frequency

A rare genetic variant of BPIFB4 predisposes to high blood pressure via impairment of nitric oxide signaling

Vecchione, C., Villa, F., Carrizzo, A., Spinelli, C. C., Damato, A., Ambrosio, M., Ferrario, A., Madonna, M., Uccellatore, A., Lupini, S., Maciag, A., Ryskalin, L., Milanesi, L., Frati, G., Sciarretta, S., Bellazzi, R., Genovese, S., Ceriello, A., Auricchio, A., Malovini, A. & 1 others, Puca, A. A., Dec 1 2017, In : Scientific Reports. 7, 1, 9706.

Research output: Contribution to journalArticle

Nitric Oxide
Blood Pressure
Hypertension
Nitric Oxide Synthase Type III
Gene Frequency

A rare genetic variant of BPIFB4 predisposes to high blood pressure via impairment of nitric oxide signaling

Vecchione, C., Villa, F., Carrizzo, A., Spinelli, C. C., Damato, A., Ambrosio, M., Ferrario, A., Madonna, M., Uccellatore, A., Lupini, S., Maciag, A., Ryskalin, L., Milanesi, L., Frati, G., Sciarretta, S., Bellazzi, R., Genovese, S., Ceriello, A., Auricchio, A., Malovini, A. & 1 others, Puca, A. A., 2017, In : Scientific Reports. 7, 1

Research output: Contribution to journalArticle

GRN deletion in familial frontotemporal dementia showing association with clinical variability in 3 familial cases

Milan, G., Napoletano, S., Pappatà, S., Gentile, M. T., Colucci-D'Amato, L., Della Rocca, G., Maciag, A., Rossetti, C. P., Fucci, L., Puca, A., Grossi, D., Postiglione, A. & Vitale, E., May 1 2017, In : Neurobiology of Aging. 53, p. 193.e9-193.e16

Research output: Contribution to journalArticle

Frontotemporal Dementia
Dementia
Primary Progressive Aphasia
Genes
Haploinsufficiency

LAV-BPIFB4 isoform modulates eNOS signalling through Ca2+/PKC-alpha-dependent mechanism

Spinelli, C. C., Carrizzo, A., Ferrario, A., Villa, F., Damato, A., Ambrosio, M., Madonna, M., Frati, G., Fucile, S., Sciaccaluga, M., Capunzo, M., Calì, G., Milanesi, L., Maciag, A., Puca, A. A. & Vecchione, C., 2017, In : Cardiovascular Research. 113, 7, p. 795-804 10 p.

Research output: Contribution to journalArticle

LAV-BPIFB4 isoform modulates eNOS signalling through Ca2+/PKC-alpha-dependent mechanism

Spinelli, C. C., Carrizzo, A., Ferrario, A., Villa, F., Damato, A., Ambrosio, M., Madonna, M., Frati, G., Fucile, S., Sciaccaluga, M., Capunzo, M., Calì, G., Milanesi, L., Maciag, A., Puca, A. A. & Vecchione, C., Jan 1 2017, In : Cardiovascular Research. 113, 7, p. 795-804 10 p.

Research output: Contribution to journalArticle

Protein Kinase C-alpha
Nitric Oxide Synthase Type III
Permeability
Protein Isoforms
Endothelium
2015

Genetic analysis reveals a longevity-associated protein modulating endothelial function and angiogenesis

Villa, F., Carrizzo, A., Spinelli, C. C., Ferrario, A., Malovini, A., Maciąg, A., Damato, A., Auricchio, A., Spinetti, G., Sangalli, E., Dang, Z., Madonna, M., Ambrosio, M., Sitia, L., Bigini, P., Calì, G., Schreiber, S., Perls, T., Fucile, S., Mulas, F. & 5 others, Nebel, A., Bellazzi, R., Madeddu, P., Vecchione, C. & Puca, A. A., Jul 1 2015, In : Circulation Research. 117, 4, p. 333-345 13 p.

Research output: Contribution to journalArticle

Permeability
Proteins
Blood Vessels
Nitric Oxide Synthase Type III
Homeostasis

Serum BPIFB4 levels classify health status in long-living individuals

Villa, F., Malovini, A., Carrizzo, A., Spinelli, C. C., Ferrario, A., Maciag, A., Madonna, M., Bellazzi, R., Milanesi, L., Vecchione, C. & Puca, A. A., Dec 15 2015, In : Immunity and Ageing. 12, 1, 27.

Research output: Contribution to journalArticle

Health Status
Serum
Blood Proteins
Genetic Models
Haplotypes
2014

A G613A missense in the Hutchinson's progeria lamin A/C gene causes a lone, autosomal dominant atrioventricular block

Villa, F., Maciag, A., Spinelli, C. C., Ferrario, A., Carrizzo, A., Parisi, A., Torella, A., Montenero, C., Condorelli, G., Vecchione, C., Nigro, V., Montenero, A. S. & Puca, A. A., Nov 26 2014, In : Immunity and Ageing. 11, 1, 19.

Research output: Contribution to journalArticle

Progeria
Lamin Type A
Atrioventricular Block
Genes
Mutation
2013

Antioxidant effects of resveratrol in cardiovascular, cerebral and metabolic diseases

Carrizzo, A., Forte, M., Damato, A., Trimarco, V., Salzano, F., Bartolo, M., Maciag, A., Puca, A. A. & Vecchione, C., Nov 2013, In : Food and Chemical Toxicology. 61, p. 215-226 12 p.

Research output: Contribution to journalArticle

Metabolic Diseases
resveratrol
metabolic diseases
Cardiovascular Diseases
Antioxidants

Vascular ageing: The role of oxidative stress

Puca, A. A., Carrizzo, A., Villa, F., Ferrario, A., Casaburo, M., MacIa̧g, A. & Vecchione, C., Mar 2013, In : International Journal of Biochemistry and Cell Biology. 45, 3, p. 556-559 4 p.

Research output: Contribution to journalArticle

Oxidative stress
Blood Vessels
Reactive Oxygen Species
Oxidative Stress
Aging of materials