• 456 Citations
  • 14 h-Index
20072019
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Research Output 2007 2019

  • 456 Citations
  • 14 h-Index
  • 31 Article
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Article
2019
Open Access
Induced Pluripotent Stem Cells
Dystrophin
Duchenne Muscular Dystrophy
Exons
Cell Line
2018
Dystrophin
Precision Medicine
Molecular Evolution
Cardiomyopathies
Muscular Dystrophies
Dystrophin
Duchenne Muscular Dystrophy
Cardiac Myocytes
Fibrosis
Inbred mdx Mouse
Induced Pluripotent Stem Cells
Dystrophin
Duchenne Muscular Dystrophy
Exons
Genes
1 Citation (Scopus)

Generation of induced pluripotent stem cells from a Becker muscular dystrophy patient carrying a deletion of exons 45-55 of the dystrophin gene (CCMi002BMD-A-9 ∆45-55)

Gowran, A., Spaltro, G., Casalnuovo, F., Vigorelli, V., Spinelli, P., Castiglioni, E., Rovina, D., Paganini, S., Di Segni, M., Gervasini, C., Nigro, P. & Pompilio, G., Apr 1 2018, In : Stem Cell Research. 28, p. 21-24 4 p.

Research output: Contribution to journalArticle

Induced Pluripotent Stem Cells
Dystrophin
Duchenne Muscular Dystrophy
Exons
Genes
Rubinstein-Taybi Syndrome
Induced Pluripotent Stem Cells
Exons
Cell Line
Mutation
Rubinstein-Taybi Syndrome
Induced Pluripotent Stem Cells
Exons
Cell Line
Mutation
2017
2 Citations (Scopus)

Derivation of the Duchenne muscular dystrophy patient-derived induced pluripotent stem cell line lacking DMD exons 49 and 50 (CCMi001DMD-A-3, ∆49, ∆50)

Spaltro, G., Vigorelli, V., Casalnuovo, F., Spinelli, P., Castiglioni, E., Rovina, D., Paganini, S., Di Segni, M., Nigro, P., Gervasini, C., Pompilio, G. & Gowran, A., Dec 2017, In : Stem Cell Research. 25, p. 128-131 4 p.

Research output: Contribution to journalArticle

Induced Pluripotent Stem Cells
Duchenne Muscular Dystrophy
Exons
Cell Line
Dystrophin
2 Citations (Scopus)

Derivation of the Duchenne muscular dystrophy patient-derived induced pluripotent stem cell line lacking DMD exons 49 and 50 (CCMi001DMD-A-3, ∆ 49, ∆ 50)

Spaltro, G., Vigorelli, V., Casalnuovo, F., Spinelli, P., Castiglioni, E., Rovina, D., Paganini, S., Di Segni, M., Nigro, P., Gervasini, C., Pompilio, G. & Gowran, A., Dec 1 2017, In : Stem Cell Research. 25, p. 128-131 4 p.

Research output: Contribution to journalArticle

Induced Pluripotent Stem Cells
Duchenne Muscular Dystrophy
Exons
Cell Line
Dystrophin
18 Citations (Scopus)

Vascular smooth muscle cells in Marfan syndrome aneurysm: the broken bricks in the aortic wall

Perrucci, GL., Rurali, E., Gowran, A., Pini, A., Antona, C., Chiesa, R., Pompilio, G. & Nigro, P., 2017, In : Cellular and Molecular Life Sciences. 74, 2, p. 267-277 11 p.

Research output: Contribution to journalArticle

Marfan Syndrome
Vascular Smooth Muscle
Smooth Muscle Myocytes
Aneurysm
Aorta
2016

The nuclear pore protein Nup153 associates with chromatin and regulates cardiac gene expression in dystrophic mdx hearts

Nanni, S., Re, A., Ripoli, C., Gowran, A., Nigro, P., D'Amario, D., Amodeo, A., Crea, F., Grassi, C., Pontecorvi, A., Farsetti, A. & Colussi, C., Nov 1 2016, In : Cardiovascular Research. 112, 2, p. 555-567 13 p.

Research output: Contribution to journalArticle

Nuclear Pore
Porins
Nuclear Proteins
Chromatin
Gene Expression
14 Citations (Scopus)

The nuclear pore protein Nup153 associates with chromatin and regulates cardiac gene expression in dystrophic mdx hearts

Nanni, S., Re, A., Ripoli, C., Gowran, A., Nigro, P., D'Amario, D., Amodeo, A., Crea, F., Grassi, C., Pontecorvi, A., Farsetti, A. & Colussi, C., Nov 1 2016, In : Cardiovascular Research. 112, 2, p. 555-567 13 p.

Research output: Contribution to journalArticle

Nuclear Pore
Porins
Nuclear Proteins
Chromatin
Gene Expression
18 Citations (Scopus)

Vascular smooth muscle cells in Marfan syndrome aneurysm: the broken bricks in the aortic wall

Perrucci, G. L., Rurali, E., Gowran, A., Pini, A., Antona, C., Chiesa, R., Pompilio, G. & Nigro, P., Aug 17 2016, (Accepted/In press) In : Cellular and Molecular Life Sciences. p. 1-11 11 p.

Research output: Contribution to journalArticle

Marfan Syndrome
Vascular Smooth Muscle
Smooth Muscle Myocytes
Aneurysm
Aorta
2 Citations (Scopus)

Young at heart: Pioneering approaches to model nonischaemic cardiomyopathy with induced pluripotent stem cells

Gowran, A., Rasponi, M., Visone, R., Nigro, P., Perrucci, G. L., Righetti, S., Zanobini, M. & Pompilio, G., 2016, In : Stem Cells International. 2016, 4287158.

Research output: Contribution to journalArticle

Induced Pluripotent Stem Cells
Cardiomyopathies
Preclinical Drug Evaluations
Stem Cells
Fibroblasts
2015
18 Citations (Scopus)

C-kit+ cells: The tell-tale heart of cardiac regeneration?

Nigro, P., Perrucci, G. L., Gowran, A., Zanobini, M., Capogrossi, M. C. & Pompilio, G., May 1 2015, In : Cellular and Molecular Life Sciences. 72, 9, p. 1725-1740 16 p.

Research output: Contribution to journalArticle

Regeneration
Cardiovascular Diseases
Stem Cells
Cell- and Tissue-Based Therapy
Cardiac Myocytes
14 Citations (Scopus)

Peptidyl-prolyl isomerases: A full cast of critical actors in cardiovascular diseases

Perrucci, G. L., Gowran, A., Zanobini, M., Capogrossi, M. C., Pompilio, G. & Nigro, P., Jun 1 2015, In : Cardiovascular Research. 106, 3, p. 353-364 12 p.

Research output: Contribution to journalArticle

Peptidylprolyl Isomerase
Cardiovascular Diseases
Immunophilins
Tacrolimus Binding Proteins
Cyclophilins
2013
12 Citations (Scopus)
Cannabinoid Receptors
Mesenchymal Stromal Cells
Cell Differentiation
Cell Survival
Bone and Bones
2012
3 Citations (Scopus)

Cannabinoid receptors and neurodegenerative diseases

Tanveer, R., Mcguinness, N., Daniel, S., Gowran, A. & Campbell, V. A., Sep 2012, In : Wiley Interdisciplinary Reviews: Membrane Transport and Signaling. 1, 5, p. 633-639 7 p.

Research output: Contribution to journalArticle

Cannabinoid Receptors
Neurodegenerative Diseases
Endocannabinoids
Cannabinoids
Therapeutic Human Experimentation
28 Citations (Scopus)

The endocannabinoid, anandamide, augments notch-1 signaling in cultured cortical neurons exposed to amyloid- β and in the cortex of aged rats

Tanveer, R., Gowran, A., Noonan, J., Keating, S. E., Bowie, A. G. & Campbell, V. A., Oct 5 2012, In : Journal of Biological Chemistry. 287, 41, p. 34709-34721 13 p.

Research output: Contribution to journalArticle

Endocannabinoids
Amyloid
Neurons
Rats
Alzheimer Disease
36 Citations (Scopus)

The fatty acid amide hydrolase inhibitor URB597 exerts anti-inflammatory effects in hippocampus of aged rats and restores an age-related deficit in long-term potentiation

Murphy, N., Cowley, T. R., Blau, C. W., Dempsey, C. N., Noonan, J., Gowran, A., Tanveer, R., Olango, W. M., Finn, D. P., Campbell, V. A. & Lynch, M. A., Apr 26 2012, In : Journal of Neuroinflammation. 9, 79.

Research output: Contribution to journalArticle

Endocannabinoids
Long-Term Potentiation
Hippocampus
Anti-Inflammatory Agents
Dentate Gyrus
2011
67 Citations (Scopus)

The multiplicity of action of cannabinoids: Implications for treating neurodegeneration

Gowran, A., Noonan, J. & Campbell, V. A., Dec 2011, In : CNS Neuroscience and Therapeutics. 17, 6, p. 637-644 8 p.

Research output: Contribution to journalArticle

Cannabinoids
Cannabinoid Receptors
Artificial Receptors
Neurogenesis
Appetite
2010
21 Citations (Scopus)

A role for p53 in the β-amyloid-mediated regulation of the lysosomal system

Fogarty, M. P., McCormack, R. M., Noonan, J., Murphy, D., Gowran, A. & Campbell, V. A., Oct 2010, In : Neurobiology of Aging. 31, 10, p. 1774-1786 13 p.

Research output: Contribution to journalArticle

Amyloid
Cathepsin L
Tumor Suppressor Protein p53
Neurons
Lysosomes
33 Citations (Scopus)

Endocannabinoids prevent β-amyloid-mediated lysosomal destabilization in cultured neurons

Noonan, J., Tanveer, R., Klompas, A., Gowran, A., McKiernan, J. & Campbell, V. A., Dec 3 2010, In : Journal of Biological Chemistry. 285, 49, p. 38543-38554 12 p.

Research output: Contribution to journalArticle

Endocannabinoids
Amyloid
Neurons
Lysosomes
Cell Survival
7 Citations (Scopus)

Tissue engineering of cartilage; can cannabinoids help?

Gowran, A., McKayed, K., Kanichai, M., White, C., Hammadi, N. & Campbell, V., 2010, In : Pharmaceuticals. 3, 9, p. 2970-2985 16 p.

Research output: Contribution to journalArticle

Cannabinoids
Tissue Engineering
Cartilage
Mesenchymal Stromal Cells
Chondrocytes
2009
11 Citations (Scopus)

Δ9-Tetrahydrocannabinol regulates the p53 post-translational modifiers Murine double minute 2 and the Small Ubiquitin MOdifier protein in the rat brain

Gowran, A., Murphy, C. E. & Campbell, V. A., Nov 3 2009, In : FEBS Letters. 583, 21, p. 3412-3418 7 p.

Research output: Contribution to journalArticle

Dronabinol
Ubiquitin
Rats
Brain
Cannabinoid Receptor CB1
2008
21 Citations (Scopus)
Dronabinol
Neurons
Rats
Permeability
Cannabinoid Receptor CB1
2007
18 Citations (Scopus)

A comparison of the apoptotic effect of Δ9-tetrahydrocannabinol in the neonatal and adult rat cerebral cortex

Downer, E. J., Gowran, A. & Campbell, V. A., Oct 17 2007, In : Brain Research. 1175, 1, p. 39-47 9 p.

Research output: Contribution to journalArticle

Dronabinol
Cerebral Cortex
Brain
Cannabis
Caspase 3
91 Citations (Scopus)

Alzheimer's disease; taking the edge off with cannabinoids?

Campbell, V. A. & Gowran, A., Nov 2007, In : British Journal of Pharmacology. 152, 5, p. 655-662 8 p.

Research output: Contribution to journalArticle

Cannabinoids
Alzheimer Disease
Neurogenesis
Nerve Growth Factors
Amyloid
19 Citations (Scopus)

The tumour suppressor protein, p53, is involved in the activation of the apoptotic cascade by Δ9-tetrahydrocannabinol in cultured cortical neurons

Downer, E. J., Gowran, A., Murphy, Á. C. & Campbell, V. A., Jun 14 2007, In : European Journal of Pharmacology. 564, 1-3, p. 57-65 9 p.

Research output: Contribution to journalArticle

Tumor Suppressor Protein p53
Dronabinol
Neurons
Cannabinoid Receptor CB1
Cannabinoids