Barbara Bellei &ndash; Research Output

2018

Adipose tissue-derived extracellular fraction characterization: biological and clinical considerations in regenerative medicine

Bellei, B., Migliano, E., Tedesco, M., Caputo, S., Papaccio, F., Lopez, G. & Picardo, M., Aug 9 2018, In : Stem Cell Research and Therapy. 9, 1, p. 207 18 p.

Research output: Contribution to journal › Article

Regenerative Medicine

Adipose Tissue

Tissue

Repair

Fibroblasts

Inhibition of Stearoyl-CoA desaturase 1 reverts BRAF and MEK inhibition-induced selection of cancer stem cells in BRAF-mutated melanoma

Pisanu, M. E., Maugeri-Saccà, M., Fattore, L., Bruschini, S., De Vitis, C., Tabbì, E., Bellei, B., Migliano, E., Kovacs, D., Camera, E., Picardo, M., Jakopin, Z., Cippitelli, C., Bartolazzi, A., Raffa, S., Torrisi, M. R., Fulciniti, F., Ascierto, P. A., Ciliberto, G. & Mancini, R., Dec 17 2018, In : Journal of Experimental and Clinical Cancer Research. 37, 1, p. 318 17 p.

Research output: Contribution to journal › Article

Stearoyl-CoA Desaturase

Neoplastic Stem Cells

Mitogen-Activated Protein Kinase Kinases

Melanoma

Drug Resistance

2017

8 Citations (Scopus)

Energetic mitochondrial failing in vitiligo and possible rescue by cardiolipin

Dell'Anna, M. L., Ottaviani, M., Kovacs, D., Mirabilii, S., Brown, D. A., Cota, C., Migliano, E., Bastonini, E., Bellei, B., Cardinali, G., Ricciardi, M. R., Tafuri, A. & Picardo, M., Oct 20 2017, In : Scientific Reports. 7, 1, 13663.

Research output: Contribution to journal › Article

Vitiligo

Cardiolipins

Melanocytes

Adenosine Triphosphate

Phosphotransferases

13 Citations (Scopus)

Maximizing non-enzymatic methods for harvesting adipose-derived stem from lipoaspirate: Technical considerations and clinical implications for regenerative surgery

Bellei, B., Migliano, E., Tedesco, M., Caputo, S. & Picardo, M., Aug 30 2017, In : Scientific Reports. 7, 1, 10015.

Research output: Contribution to journal › Article

Adipose Tissue

Mesenchymal Stromal Cells

Fats

Vitiligo

Adult Stem Cells

2 Citations (Scopus)

The activation of PPARγ by 2,4,6-Octatrienoic acid protects human keratinocytes from UVR-induced damages

Flori, E., Mastrofrancesco, A., Kovacs, D., Bellei, B., Briganti, S., Maresca, V., Cardinali, G. & Picardo, M., Aug 23 2017, In : Scientific Reports. 7, 1, 9241.

Research output: Contribution to journal › Article

Peroxisome Proliferator-Activated Receptors

Keratinocytes

Melanocyte-Stimulating Hormones

Skin

Antioxidants

2 Citations (Scopus)

The α-melanocyte stimulating hormone/peroxisome proliferator activated receptor-γ pathway down-regulates proliferation in melanoma cell lines

Flori, E., Rosati, E., Cardinali, G., Kovacs, D., Bellei, B., Picardo, M. & Maresca, V., Oct 11 2017, In : Journal of Experimental and Clinical Cancer Research. 36, 1, 142.

Research output: Contribution to journal › Article

Melanocyte-Stimulating Hormones

Peroxisome Proliferator-Activated Receptors

Melanoma

Down-Regulation

Cell Line

2016

12 Citations (Scopus)

miR-211 and MITF modulation by Bcl-2 protein in melanoma cells

De Luca, T., Pelosi, A., Trisciuoglio, D., D'Aguanno, S., Desideri, M., Farini, V., Di Martile, M., Bellei, B., Tupone, M. G., Candiloro, A., Regazzo, G., Rizzo, M. G. & Del Bufalo, D., Dec 1 2016, In : Molecular Carcinogenesis. 55, 12, p. 2304-2312 9 p.

Research output: Contribution to journal › Article

Microphthalmia-Associated Transcription Factor

Melanoma

Transient Receptor Potential Channels

Proteins

Chromatin Immunoprecipitation

15 Citations (Scopus)

The role of Wnt/β-catenin signaling pathway in melanoma epithelial-to-mesenchymal-like switching: Evidences from patients-derived cell lines

Kovacs, D., Migliano, E., Muscardin, L., Silipo, V., Catricalà, C., Picardo, M. & Bellei, B., 2016, In : Oncotarget. 7, 28, p. 43295-43314 20 p.

Research output: Contribution to journal › Article

Catenins

Wnt Signaling Pathway

Melanoma

Cell Line

Neoplasms

2014

7 Citations (Scopus)

Fat and epidermal cell suspension grafting: A new advanced one-step skin regeneration surgical technique

Migliano, E., Bellei, B., Govoni, F. A., Bucher, S. & Picardo, M., Feb 24 2014, In : Journal of Experimental and Clinical Cancer Research. 33, 1, 23.

Research output: Contribution to journal › Article

Adipocytes

Regeneration

Suspensions

Skin

Cicatrix

15 Citations (Scopus)

Modulation of PPARγ provides new insights in a stress induced premature senescence model

Briganti, S., Flori, E., Bellei, B. & Picardo, M., Aug 7 2014, In : PLoS One. 9, 8, e104045.

Research output: Contribution to journal › Article

PPAR gamma

Modulation

Antioxidants

skin (animal)

Skin

35 Citations (Scopus)

Monozygotic twins discordant for recessive dystrophic epidermolysis bullosa phenotype highlight the role of TGF-β signalling in modifying disease severity

Odorisio, T., di Salvio, M., Orecchia, A., di Zenzo, G., Piccinni, E., Cianfarani, F., Travaglione, A., Uva, P., Bellei, B., Conti, A., Zambruno, G. & Castiglia, D., 2014, In : Human Molecular Genetics. 23, 15, p. 3907-3922 16 p., ddu102.

Research output: Contribution to journal › Article

Epidermolysis Bullosa Dystrophica

Monozygotic Twins

Decorin

Phenotype

Fibroblasts

4 Citations (Scopus)

Pyridinyl imidazole compounds interfere with melanosomes sorting through the inhibition of Cyclin G-associated Kinase, a regulator of cathepsins maturation

Bellei, B., Pitisci, A., Migliano, E., Cardinali, G. & Picardo, M., Apr 2014, In : Cellular Signalling. 26, 4, p. 716-723 8 p.

Research output: Contribution to journal › Article

Cyclin G

Melanosomes

Cathepsins

Melanocytes

Melanins

2013

16 Citations (Scopus)

Linking αMSH with PPARγ in B16-F10 melanoma

Maresca, V., Flori, E., Camera, E., Bellei, B., Aspite, N., Ludovici, M., Catricalà, C., Cardinali, G. & Picardo, M., Jan 2013, In : Pigment Cell and Melanoma Research. 26, 1, p. 113-127 15 p.

Research output: Contribution to journal › Article

Melanocyte-Stimulating Hormones

Experimental Melanomas

Peroxisome Proliferator-Activated Receptors

Programmable logic controllers

Receptor, Melanocortin, Type 1

6 Citations (Scopus)

PNA as a potential modulator of COL7A1 gene expression in dominant dystrophic epidermolysis bullosa: A physico-chemical study

Amato, J., Stellato, M. I., Pizzo, E., Petraccone, L., Oliviero, G., Borbone, N., Piccialli, G., Orecchia, A., Bellei, B., Castiglia, D. & Giancola, C., Dec 2013, In : Molecular BioSystems. 9, 12, p. 3166-3174 9 p.

Research output: Contribution to journal › Article

Epidermolysis Bullosa Dystrophica

Peptide Nucleic Acids

Gene Expression

Alleles

Nucleic Acid Heteroduplexes

5 Citations (Scopus)

SLN melanoma micrometastasis predictivity of nodal status: A long term retrospective study

Migliano, E., Bellei, B., Govoni, F. A., Paolino, G., Catricalà, C., Bucher, S. & Donati, P., 2013, In : Journal of Experimental and Clinical Cancer Research. 32, 1, 47.

Research output: Contribution to journal › Article

Neoplasm Micrometastasis

Lymph Node Excision

Melanoma

Retrospective Studies

Neoplasm Metastasis

37 Citations (Scopus)

Vitiligo: A Possible Model of Degenerative Diseases

Bellei, B., Pitisci, A., Ottaviani, M., Ludovici, M., Cota, C., Luzi, F., Dell'Anna, M. L. & Picardo, M., Mar 26 2013, In : PLoS One. 8, 3, e59782.

Research output: Contribution to journal › Article

Vitiligo

Oxidative stress

melanocytes

Melanocytes

Neurodegenerative diseases

2012

20 Citations (Scopus)

Inhibition of melanogenesis by the pyridinyl imidazole class of compounds: Possible involvement of the Wnt/β-catenin signaling pathway

Bellei, B., Pitisci, A., Izzo, E. & Picardo, M., Mar 13 2012, In : PLoS One. 7, 3, e33021.

Research output: Contribution to journal › Article

melanogenesis

Catenins

Wnt Signaling Pathway

imidazoles

mitogen-activated protein kinase

13 Citations (Scopus)

In vitro research on vitiligo: Strategies, principles, methodological options and common pitfalls

Dell'Anna, M. L., Cario-André, M., Bellei, B., Taieb, A. & Picardo, M., Jul 2012, In : Experimental Dermatology. 21, 7, p. 490-496 7 p.

Research output: Contribution to journal › Article

Vitiligo

Cytology

Fluorescent Dyes

Cell culture

Research

2011

31 Citations (Scopus)

2,4,6-Octatrienoic acid is a novel promoter of melanogenesis and antioxidant defence in normal human melanocytes via PPAR-γ activation

Flori, E., Mastrofrancesco, A., Kovacs, D., Ramot, Y., Briganti, S., Bellei, B., Paus, R. & Picardo, M., Aug 2011, In : Pigment Cell and Melanoma Research. 24, 4, p. 618-630 13 p.

Research output: Contribution to journal › Article

Peroxisome Proliferator-Activated Receptors

Melanocytes

Antioxidants

Chemical activation

Skin

53 Citations (Scopus)

Wnt/β-catenin signaling is stimulated by α-melanocyte-stimulating hormone in melanoma and melanocyte cells: Implication in cell differentiation

Bellei, B., Pitisci, A., Catricalà, C., Larue, L. & Picardo, M., Apr 2011, In : Pigment Cell and Melanoma Research. 24, 2, p. 309-325 17 p.

Research output: Contribution to journal › Article

Melanocyte-Stimulating Hormones

Catenins

Melanocytes

Cell Differentiation

Melanoma

2010

23 Citations (Scopus)

MC1R stimulation by α-MSH induces catalase and promotes its re-distribution to the cell periphery and dendrites

Maresca, V., Flori, E., Bellei, B., Aspite, N., Kovacs, D. & Picardo, M., Apr 2010, In : Pigment Cell and Melanoma Research. 23, 2, p. 263-275 13 p.

Research output: Contribution to journal › Article

Receptor, Melanocortin, Type 1

Melanocyte-Stimulating Hormones

Dendrites

Catalase

Oxidants

28 Citations (Scopus)

Membrane lipid defects are responsible for the generation of reactive oxygen species in peripheral blood mononuclear cells from vitiligo patients

Dell'Anna, M. L., Ottaviani, M., Bellei, B., Albanesi, V., Cossarizza, A., Rossi, L. & Picardo, M., Apr 1 2010, In : Journal of Cellular Physiology. 223, 1, p. 187-193 7 p.

Research output: Contribution to journal › Article

Vitiligo

Membrane Lipids

Reactive Oxygen Species

Blood Cells

Cardiolipins

72 Citations (Scopus)

p38 regulates pigmentation via proteasomal degradation of tyrosinase

Bellei, B., Maresca, V., Flori, E., Pitisci, A., Larue, L. & Picardo, M., Mar 5 2010, In : Journal of Biological Chemistry. 285, 10, p. 7288-7299 12 p.

Research output: Contribution to journal › Article

Monophenol Monooxygenase

Pigmentation

p38 Mitogen-Activated Protein Kinases

Melanocyte-Stimulating Hormones

Degradation

52 Citations (Scopus)

Role of fibroblast-derived growth factors in regulating hyperpigmentation of solar lentigo

Kovacs, D., Cardinali, G., Aspite, N., Cota, C., Luzi, F., Bellei, B., Briganti, S., Amantea, A., Torrisi, M. R. & Picardo, M., Nov 2010, In : British Journal of Dermatology. 163, 5, p. 1020-1027 8 p.

Research output: Contribution to journal › Article

Lentigo

Hyperpigmentation

Fibroblast Growth Factor 7

Fibroblast Growth Factors

Keratinocytes

2008

80 Citations (Scopus)

GSK3β inhibition promotes melanogenesis in mouse B16 melanoma cells and normal human melanocytes

Bellei, B., Flori, E., Izzo, E., Maresca, V. & Picardo, M., Oct 2008, In : Cellular Signalling. 20, 10, p. 1750-1761 12 p.

Research output: Contribution to journal › Article

Glycogen Synthase Kinase 3

Experimental Melanomas

Melanocytes

Catenins

Wnt Signaling Pathway

36 Citations (Scopus)

Small molecular antioxidants effectively protect from PUVA-induced oxidative stress responses underlying fibroblast senescence and photoaging

Briganti, S., Wlaschek, M., Hinrichs, C., Bellei, B., Flori, E., Treiber, N., Iben, S., Picardo, M. & Scharffetter-Kochanek, K., Sep 1 2008, In : Free Radical Biology and Medicine. 45, 5, p. 636-644 9 p.

Research output: Contribution to journal › Article

Oxidative stress

Fibroblasts

Oxidative Stress

Antioxidants

Irradiation

22 Citations (Scopus)

Ultraviolet A induced modulation of gap junctional intercellular communication by P38 MAPK activation in human keratinocytes

Bellei, B., Mastrofrancesco, A., Briganti, S., Aspite, N., Ale-agha, N., Sies, H. & Picardo, M., Feb 2008, In : Experimental Dermatology. 17, 2, p. 115-124 10 p.

Research output: Contribution to journal › Article

p38 Mitogen-Activated Protein Kinases

Keratinocytes

Connexin 43

Chemical activation

Modulation

2006

8 Citations (Scopus)

Association of p53 Arg72Pro polymorphism and β-catenin accumulation in mycosis fungoides

Bellei, B., Cota, C., Amantea, A., Muscardin, L. & Picardo, M., Dec 2006, In : British Journal of Dermatology. 155, 6, p. 1223-1229 7 p.

Research output: Contribution to journal › Article

Catenins

Mycosis Fungoides

Cutaneous T-Cell Lymphoma

Mutation

Exons

2004

24 Citations (Scopus)

Frequent β-catenin overexpression without exon 3 mutation in cutaneous lymphomas

Bellei, B., Pacchiarotti, A., Perez, M. & Faraggiana, T., Oct 2004, In : Modern Pathology. 17, 10, p. 1275-1281 7 p.

Research output: Contribution to journal › Article

Catenins

Exons

Lymphoma

Skin

Mutation