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Research Output 2000 2019

  • 69 Article
  • 12 Review article
  • 3 Conference contribution
  • 1 Short survey
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Article
2019

Acid sensing ion channel 2: A new potential player in the pathophysiology of multiple sclerosis

Fazia, T., Pastorino, R., Notartomaso, S., Busceti, C., Imbriglio, T., Cannella, M., Gentilini, D., Morani, G., Ticca, A., Bitti, P., Berzuini, C., Dalmay, T., Battaglia, G. & Bernardinelli, L., May 2019, In : European Journal of Neuroscience. 49, 10, p. 1233-1243 11 p.

Research output: Contribution to journalArticle

Open Access
Acid Sensing Ion Channels
Multiple Sclerosis
Immunization
Pain Threshold
Autoimmune Experimental Encephalomyelitis
glucocorticoids
catecholamine
gene expression
Corticosterone
markers

Motor Neurons Pathology After Chronic Exposure to MPTP in Mice

Vivacqua, G., Biagioni, F., Busceti, C. L., Ferrucci, M., Madonna, M., Ryskalin, L., Yu, S., D'Este, L. & Fornai, F., Nov 13 2019, In : Neurotoxicity Research.

Research output: Contribution to journalArticle

Motor Neurons
Pathology
Neurons
Spinal Cord
Parkinsonian Disorders
Reticular Formation
Methamphetamine
Amphetamine
Brain Stem
Acetylcholine
2018

Dickkopf-3 causes neuroprotection by inducing vascular endothelial growth factor

Busceti, C. L., Di Menna, L., Bianchi, F., Mastroiacovo, F., Di Pietro, P., Traficante, A., Bozza, G., Niehrs, C., Battaglia, G., Bruno, V., Fornai, F., Volpe, M., Rubattu, S. & Nicoletti, F., Sep 11 2018, In : Frontiers in Cellular Neuroscience. 12, 292.

Research output: Contribution to journalArticle

Astrocytes
Vascular Endothelial Growth Factor A
N-Methylaspartate
Neurons
Neuroprotection

MTOR modulates methamphetamine-induced toxicity through cell clearing systems

Lazzeri, G., Biagioni, F., Fulceri, F., Busceti, C. L., Scavuzzo, M. C., Ippolito, C., Salvetti, A., Lenzi, P. & Fornai, F., Oct 29 2018, In : Oxidative Medicine and Cellular Longevity. 2018, 6124745.

Research output: Contribution to journalArticle

Methamphetamine
Toxicity
Autophagy
Proteasome Endopeptidase Complex
Ubiquitin
2017
Cerebrovascular Disorders
Inbred SHR Rats
MicroRNAs
Rats
Brain

A small dose of apomorphine counteracts the deleterious effects of middle cerebral artery occlusion in different models

Mastroiacovo, F., Gaglione, A., Busceti, C. L., Ryskalin, L., Bozza, G., Nicoletti, F., Orzi, F. & Fornai, F., Jan 1 2017, In : Archives Italiennes de Biologie. 155, 3, p. 110-117 8 p.

Research output: Contribution to journalArticle

Apomorphine
Middle Cerebral Artery Infarction
Basal Ganglia
Muscle Strength
Neuroprotective Agents
Activin Receptors
Vascular Endothelial Growth Factor A
Up-Regulation
Endothelial Cells
Type I Bone Morphogenetic Protein Receptors

Methamphetamine increases prion protein and induces dopamine-dependent expression of protease resistant PrPsc

Ferrucci, M., Ryskalin, L., Biagioni, F., Gambardella, S., Busceti, C. L., Falleni, A., Lazzeri, G. & Fornai, F., Jul 1 2017, In : Archives Italiennes de Biologie. 155, 1-2, p. 81-97 17 p.

Research output: Contribution to journalArticle

Methamphetamine
Dopamine
Peptide Hydrolases
Corpus Striatum
Secondary Protein Structure

Systematic morphometry of catecholamine nuclei in the brainstem

Bucci, D., Busceti, C. L., Calierno, M. T., Di Pietro, P., Madonna, M., Biagioni, F., Ryskalin, L., Limanaqi, F., Nicoletti, F. & Fornai, F., Nov 2 2017, In : Frontiers in Neuroanatomy. 11, 98.

Research output: Contribution to journalArticle

Reticular Formation
Brain Stem
Catecholamines
Tyrosine 3-Monooxygenase
Neurons
Reticular Formation
Brain Stem
Parkinson Disease
Phenotype
Point Mutation
Enteric Nervous System
Organogenesis
Catecholamines
Anatomy
Neurons
2016

The autophagoproteasome a novel cell clearing organelle in baseline and stimulated conditions

Lenzi, P., Lazzeri, G., Biagioni, F., Busceti, C. L., Gambardella, S., Salvetti, A. & Fornai, F., Jul 21 2016, In : Frontiers in Neuroanatomy. 10, JUL, 78.

Research output: Contribution to journalArticle

Autophagy
Organelles
Proteasome Endopeptidase Complex
Ubiquitin
Sirolimus

The inflammatory protein Pentraxin 3 in cardiovascular disease

Fornai, F., Carrizzo, A., Forte, M., Ambrosio, M., Damato, A., Ferrucci, M., Biagioni, F., Busceti, C., Puca, A. A. & Vecchione, C., Aug 24 2016, In : Immunity and Ageing. 13, 1, 25.

Research output: Contribution to journalArticle

Cardiovascular Diseases
Proteins
Cardiovascular System
Pattern Recognition Receptors
PTX3 protein
Neurobiology
Protein Transport
Mutation Rate
Parkinson Disease
Mutation
2015
Receptor, Serotonin, 5-HT2C
tau Proteins
Neuronal Plasticity
Long-Term Memory
Long-Term Potentiation
Peroxisome Proliferator-Activated Receptors
AMP-Activated Protein Kinases
Inbred SHR Rats
Stroke
Hypertension

Monomeric ß-amyloid interacts with type-1 insulin-like growth factor receptors to provide energy supply to neurons

Giuffrida, M. L., Tomasello, M. F., Pandini, G., Caraci, F., Battaglia, G., Busceti, C., Di Pietro, P., Pappalardo, G., Attanasio, F., Chiechio, S., Bagnoli, S., Nacmias, B., Sorbi, S., Vigneri, R., Rizzarelli, E., Nicoletti, F. & Copani, A., Aug 7 2015, In : Frontiers in Cellular Neuroscience. 9, AUGUST, 297.

Research output: Contribution to journalArticle

IGF Type 1 Receptor
Amyloid
Neurons
Glucose
Amyloid beta-Protein Precursor
2014

Cinnabarinic acid, an endogenous agonist of type-4 metabotropic glutamate receptor, suppresses experimental autoimmune encephalomyelitis in mice

Fazio, F., Zappulla, C., Notartomaso, S., Busceti, C., Bessede, A., Scarselli, P., Vacca, C., Gargaro, M., Volpi, C., Allegrucci, M., Lionetto, L., Simmaco, M., Belladonna, M. L., Nicoletti, F. & Fallarino, F., 2014, In : Neuropharmacology. 81, p. 237-243 7 p.

Research output: Contribution to journalArticle

Autoimmune Experimental Encephalomyelitis
Kynurenine
Immune Tolerance
Regulatory T-Lymphocytes
Immunization

Region-specific DNA alterations in focally induced seizures

Cantafora, E., Giorgi, F. S., Frenzilli, G., Scarcelli, V., Busceti, C. L., Nigro, M., Bernardeschi, M. & Fornai, F., 2014, In : Journal of Neural Transmission. 121, 11, p. 1399-1403 5 p.

Research output: Contribution to journalArticle

Entorhinal Cortex
Seizures
DNA Damage
Hippocampus
DNA
2013

Changes of peripheral TGF-β1 depend on monocytes-derived macrophages in Huntington disease

Di Pardo, A., Alberti, S., Maglione, V., Amico, E., Cortes, E. P., Elifani, F., Battaglia, G., Busceti, C. L., Nicoletti, F., Vonsattel, J. P. G. & Squitieri, F., Dec 13 2013, In : Molecular Brain. 6, 1, 55.

Research output: Contribution to journalArticle

Huntington Disease
Transforming Growth Factors
Macrophages
Aptitude
Nerve Growth Factors

Microtubule alterations occur early in experimental parkinsonism and the microtubule stabilizer Epothilone D is neuroprotective

Cartelli, D., Casagrande, F., Busceti, C. L., Bucci, D., Molinaro, G., Traficante, A., Passarella, D., Giavini, E., Pezzoli, G., Battaglia, G. & Cappelletti, G., 2013, In : Scientific Reports. 3, 1837.

Research output: Contribution to journalArticle

Parkinsonian Disorders
Microtubules
Dopaminergic Neurons
Tubulin
Nerve Degeneration

Novel aspects of striatal plasticity associated with long-term levo-dopa administration

Busceti, C. L., Biagioni, F., Calierno, M. T., Nicoletti, F., Ruggieri, S. & Fornai, F., 2013, In : Archives Italiennes de Biologie. 151, 4, p. 192-202 11 p.

Research output: Contribution to journalArticle

Corpus Striatum
Dihydroxyphenylalanine
Parkinsonian Disorders
Tyrosine 3-Monooxygenase
Neurons

The effects of locus coeruleus and norepinephrine in methamphetamine toxicity

Ferrucci, M., Giorgi, F. S., Bartalucci, A., Busceti, C. L. & Fornai, F., 2013, In : Current Neuropharmacology. 11, 1, p. 80-94 15 p.

Research output: Contribution to journalArticle

Locus Coeruleus
Methamphetamine
Norepinephrine
Dopamine
Neuroanatomy

The neurobiology of the spinal cord in experimental parkinsonism and Parkinson's disease

Ferrucci, M., Biagioni, F., Vivacqua, G., Busceti, C. L., Bartalucci, A., Soldani, P., D'Este, L., Fumagalli, L. & Fornai, F., 2013, In : Archives Italiennes de Biologie. 151, 4, p. 219-234 16 p.

Research output: Contribution to journalArticle

Neurobiology
Parkinsonian Disorders
Parkinson Disease
Spinal Cord
Dopaminergic Neurons
2012

A subcellular analysis of genetic modulation of PINK1 on mitochondrial alterations, autophagy and cell death

Lenzi, P., Marongiu, R., Falleni, A., Gelmetti, V., Busceti, C. L., Michiorri, S., Valente, E. M. & Fornai, F., 2012, In : Archives Italiennes de Biologie. 150, 2-3, p. 194-217 24 p.

Research output: Contribution to journalArticle

Autophagy
Mitochondria
Cell Death
Mitochondrial Degradation
Methamphetamine

Lack or Inhibition of Dopaminergic Stimulation Induces a Development Increase of Striatal Tyrosine Hydroxylase-Positive Interneurons

Busceti, C. L., Bucci, D., Molinaro, G., Di Pietro, P., Zangrandi, L., Gradini, R., Moratalla, R., Battaglia, G., Bruno, V., Nicoletti, F. & Fornai, F., Sep 18 2012, In : PLoS One. 7, 9, e44025.

Research output: Contribution to journalArticle

tyrosine 3-monooxygenase
Corpus Striatum
interneurons
Tyrosine 3-Monooxygenase
Interneurons
2011

Early defect of transforming growth factor β1 formation in Huntington's disease

Battaglia, G., Cannella, M., Riozzi, B., Orobello, S., Maat-Schieman, M. L., Aronica, E., Busceti, C. L., Ciarmiello, A., Alberti, S., Amico, E., Sassone, J., Sipione, S., Bruno, V., Frati, L., Nicoletti, F. & Squitieri, F., Mar 2011, In : Journal of Cellular and Molecular Medicine. 15, 3, p. 555-571 17 p.

Research output: Contribution to journalArticle

Huntington Disease
Transforming Growth Factors
Corpus Striatum
Asymptomatic Diseases
Astrocytes

Induction of the Wnt antagonist dickkopf-1 is involved in stress-induced hippocampal damage

Matrisciano, F., Busceti, C. L., Bucci, D., Orlando, R., Caruso, A., Molinaro, G., Cappuccio, I., Riozzi, B., Gradini, R., Motolese, M., Caraci, F., Copani, A., Scaccianoce, S., Melchiorri, D., Bruno, V., Battaglia, G. & Nicoletti, F., 2011, In : PLoS One. 6, 1, e16447.

Research output: Contribution to journalArticle

antagonists
mice
Wnt Signaling Pathway
corticosterone
Corticosterone
2010

Intracellular pathways underlying the effects of lithium

Pasquali, L., Busceti, C. L., Fulceri, F., Paparelli, A. & Fornai, F., Sep 2010, In : Behavioural Pharmacology. 21, 5-6, p. 473-492 20 p.

Research output: Contribution to journalArticle

Lithium
Pharmacology
Glycogen Synthase Kinase 3
Neurogenesis
Autophagy

Metabotropic glutamate receptor-4 modulates adaptive immunity and restrains neuroinflammation

Fallarino, F., Volpi, C., Fazio, F., Notartomaso, S., Vacca, C., Busceti, C., Bicciato, S., Battaglia, G., Bruno, V., Puccetti, P., Fioretti, M. C., Nicoletti, F., Grohmann, U. & Di Marco, R., Aug 2010, In : Nature Medicine. 16, 8, p. 897-902 6 p.

Research output: Contribution to journalArticle

Adaptive Immunity
Multiple Sclerosis
Glutamic Acid
Regulatory T-Lymphocytes
Dendritic Cells

The origin recognition complex subunit, ORC3, is developmentally regulated and supports the expression of biochemical markers of neuronal maturation in cultured cerebellar granule cells

Cappuccio, I., Colapicchioni, C., Santangelo, V., Sale, P., Blandini, F., Bonelli, M., Niccolini, C., Busceti, C., Bucci, D., Nicoletti, F. & Melchiorri, D., Oct 28 2010, In : Brain Research. 1358, p. 1-10 10 p.

Research output: Contribution to journalArticle

Origin Recognition Complex
Biomarkers
Mitogens
rho-Associated Kinases
Monomeric GTP-Binding Proteins
2009

Activation of mGlu3 receptors stimulates the production of GDNF in striatal neurons

Battaglia, G., Molinaro, G., Riozzi, B., Storto, M., Busceti, C. L., Spinsanti, P., Bucci, D., Di Liberto, V., Mudò, G., Corti, C., Corsi, M., Nicoletti, F., Belluardo, N. & Bruno, V., Aug 12 2009, In : PLoS One. 4, 8, e6591.

Research output: Contribution to journalArticle

Glial Cell Line-Derived Neurotrophic Factor
Corpus Striatum
LY 379268
neurotrophins
neuroglia

Epigenetic modulation of mGlu2 receptors by histone deacetylase inhibitors in the treatment of inflammatory pain

Chiechio, S., Zammataro, M., Morales, M. E., Busceti, C. L., Drago, F., Gereau IV, R. W., Copani, A. & Nicoletti, F., May 2009, In : Molecular Pharmacology. 75, 5, p. 1014-1020 7 p.

Research output: Contribution to journalArticle

Histone Deacetylase Inhibitors
Epigenomics
Spinal Ganglia
Pain
Analgesia

Induction of the Wnt antagonist, Dickkopf-1, contributes to the development of neuronal death in models of brain focal ischemia

Mastroiacovo, F., Busceti, C. L., Biagioni, F., Moyanova, S. G., Meisler, M. H., Battaglia, G., Caricasole, A., Bruno, V. & Nicoletti, F., Feb 2009, In : Journal of Cerebral Blood Flow and Metabolism. 29, 2, p. 264-276 13 p.

Research output: Contribution to journalArticle

Wnt Signaling Pathway
Brain Ischemia
Neurons
Catenins
Middle Cerebral Artery Infarction

Tumor necrosis factor-α mediates hemolysis-induced vasoconstriction and the cerebral vasospasm evoked by subarachnoid hemorrhage

Vecchione, C., Frati, A., Di Pardo, A., Cifelli, G., Carnevale, D., Gentile, M. T., Carangi, R., Landolfi, A., Carullo, P., Bettarini, U., Antenucci, G., Mascio, G., Busceti, C. L., Notte, A., Maffei, A., Cantore, G. P. & Lembo, G., Jul 1 2009, In : Hypertension. 54, 1, p. 150-156 7 p.

Research output: Contribution to journalArticle

Intracranial Vasospasm
Subarachnoid Hemorrhage
Hemolysis
Vasoconstriction
Tumor Necrosis Factor-alpha
2008

Enhanced tau phosphorylation in the hippocampus of mice treated with 3,4-methylenedioxymethamphetamine ("Ecstasy")

Busceti, C. L., Biagioni, F., Riozzi, B., Battaglia, G., Storto, M., Cinque, C., Molinaro, G., Gradini, R., Caricasole, A., Canudas, A. M., Bruno, V., Nicoletti, F. & Fornai, F., Mar 19 2008, In : Journal of Neuroscience. 28, 12, p. 3234-3245 12 p.

Research output: Contribution to journalArticle

N-Methyl-3,4-methylenedioxyamphetamine
Hippocampus
Phosphorylation
tau Proteins
Cyclin-Dependent Kinase 5

Genetic or pharmacological blockade of noradrenaline synthesis enhances the neurochemical, behavioral, and neurotoxic effects of methamphetamine

Weinshenker, D., Ferrucci, M., Busceti, C. L., Biagioni, F., Lazzeri, G., Liles, L. C., Lenzi, P., Pasquali, L., Murri, L., Paparelli, A. & Fornai, F., Apr 2008, In : Journal of Neurochemistry. 105, 2, p. 471-483 13 p.

Research output: Contribution to journalArticle

Methamphetamine
Dopamine
Norepinephrine
Pharmacology
Corpus Striatum

High number of striatal dopaminergic neurons during early postnatal development: Correlation analysis with dopaminergic fibers

Busceti, C. L., Biagioni, F., Mastroiacovo, F., Bucci, D., Lenzi, P., Pasquali, L., Trabucco, A., Nicoletti, F. & Fornai, F., Oct 2008, In : Journal of Neural Transmission. 115, 10, p. 1375-1383 9 p.

Research output: Contribution to journalArticle

Corpus Striatum
Dopaminergic Neurons
Dopamine
Axons
Islands

TGF-β1 protects against Aβ-neurotoxicity via the phosphatidylinositol-3-kinase pathway

Caraci, F., Battaglia, G., Busceti, C., Biagioni, F., Mastroiacovo, F., Bosco, P., Drago, F., Nicoletti, F., Sortino, M. A. & Copani, A., May 2008, In : Neurobiology of Disease. 30, 2, p. 234-242 9 p.

Research output: Contribution to journalArticle

Phosphatidylinositol 3-Kinase
Transforming Growth Factors
Catenins
Cell Cycle
Injections

The Wnt antagonist, Dickkopf-1, as a target for the treatment of neurodegenerative disorders

Caraci, F., Busceti, C., Biagioni, F., Aronica, E., Mastroiacovo, F., Cappuccio, I., Battaglia, G., Bruno, V., Caricasole, A., Copani, A. & Nicoletti, F., Dec 2008, In : Neurochemical Research. 33, 12, p. 2401-2406 6 p.

Research output: Contribution to journalArticle

Wnt Signaling Pathway
Neurodegenerative Diseases
Brain
Temporal Lobe Epilepsy
Alzheimer Disease
2007

Induction of the Wnt inhibitor, Dickkopf-1, is associated with neurodegeneration related to temporal lobe epilepsy

Busceti, C. L., Biagioni, F., Aronica, E., Riozzi, B., Storto, M., Battaglia, G., Giorgi, F. S., Gradini, R., Fornai, F., Caricasole, A., Nicoletti, F. & Bruno, V., Apr 2007, In : Epilepsia. 48, 4, p. 694-705 12 p.

Research output: Contribution to journalArticle

Wnt Signaling Pathway
Temporal Lobe Epilepsy
Kainic Acid
Hippocampus
Seizures

L'occlusione permanente bilaterale delle carotidi (BCAO) nel ratto causa iperfosforilazione della proteina tau nell'ippocampo

Translated title of the contribution: BCAO induces hyperphosphorilation of tau protein in the hippocampusMangiardi, M., Busceti, C. L., Biagioni, F., Mastroiacovo, F. & Orzi, F., 2007, In : Rivista Italiana di Neurobiologia. 4, 3-4, p. 261-267 7 p.

Research output: Contribution to journalArticle

tau Proteins
Hippocampus
Alzheimer Disease
Clinical Medicine
Brain

Mechanisms involved in the formation of dopamine-induced intracellular bodies within striatal neurons

Lazzeri, G., Lenzi, P., Busceti, C. L., Ferrucci, M., Falleni, A., Bruno, V., Paparelli, A. & Fornai, F., Jun 2007, In : Journal of Neurochemistry. 101, 5, p. 1414-1427 14 p.

Research output: Contribution to journalArticle

Corpus Striatum
Methamphetamine
Neurons
Dopamine
Proteasome Endopeptidase Complex

Methamphetamine induces ectopic expression of tyrosine hydroxylase and increases noradrenaline levels within the cerebellar cortex

Ferrucci, M., Busceti, C. L., Nori, S. L., Lazzeri, G., Bovolin, P., Falleni, A., Mastroiacovo, F., Pompili, E., Fumagalli, L., Paparelli, A. & Fornai, F., Nov 23 2007, In : Neuroscience. 149, 4, p. 871-884 14 p.

Research output: Contribution to journalArticle

Cerebellar Cortex
Methamphetamine
Tyrosine 3-Monooxygenase
Norepinephrine
Cerebellum

Transglutaminase 2 ablation leads to defective function of mitochondrial respiratory complex I affecting neuronal vulnerability in experimental models of extrapyramidal disorders

Battaglia, G., Farrace, M. G., Mastroberardino, P. G., Viti, I., Fimia, G. M., Van Beeumen, J., Devreese, B., Melino, G., Molinaro, G., Busceti, C. L., Biagioni, F., Nicoletti, F. & Piacentini, M., Jan 2007, In : Journal of Neurochemistry. 100, 1, p. 36-49 14 p.

Research output: Contribution to journalArticle

Basal Ganglia Diseases
Electron Transport Complex I
Ablation
Theoretical Models
Electron Transport
2006
1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine
Metabotropic Glutamate Receptors
Pharmacology
Corpus Striatum
Dopamine Plasma Membrane Transport Proteins

Protection by apomorphine in two independent models of acute inhibition of oxidative metabolism in rodents

Castri, P., Busceti, C., Battaglia, G., Girardi, F., Cavallari, M., Orzi, F. & Fornai, F., Jul 1 2006, In : Clinical and Experimental Hypertension. 28, 3-4, p. 387-394 8 p.

Research output: Contribution to journalArticle

Apomorphine
Rodentia
1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine
Corpus Striatum
Gerbillinae
2005

AMPA receptor desensitization as a determinant of vulnerability to focally evoked status epilepticus

Fornai, F., Busceti, C. L., Kondratyev, A. & Gale, K., Jan 2005, In : European Journal of Neuroscience. 21, 2, p. 455-463 9 p.

Research output: Contribution to journalArticle

AMPA Receptors
Status Epilepticus
Seizures
Bicuculline
Carbachol