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Research Output 1987 2019

  • 1688 Citations
  • 25 h-Index
  • 75 Article
2019

FZD10 Carried by Exosomes Sustains Cancer Cell Proliferation

Scavo, M. P., Depalo, N., Rizzi, F., Ingrosso, C., Fanizza, E., Chieti, A., Messa, C., Denora, N., Laquintana, V., Striccoli, M., Curri, M. L. & Giannelli, G., Jul 25 2019, In : Cells. 8, 8, p. 1-18 18 p.

Research output: Contribution to journalArticle

Exosomes
Cell proliferation
Cell Proliferation
Messenger RNA
Carcinogenesis
alpha-Fetoproteins
Cell Movement
Hepatocellular Carcinoma
Growth
Apoptosis
2018

Cannabinoid Receptor-1 Up-regulation in Azoxymethane (AOM)-treated Mice After Dietary Treatment with Quercetin

Tutino, V., DE Nunzio, V., Tafaro, A., Bianco, G., Gigante, I., Scavo, M. P., D'Alessandro, R., Refolo, M. G., Messa, C., Caruso, M. G. & Notarnicola, M., Aug 2018, In : Anticancer Research. 38, 8, p. 4485-4491 7 p.

Research output: Contribution to journalArticle

Azoxymethane
Cannabinoid Receptors
Quercetin
Up-Regulation
Diet

Chlorogenic Acid Improves the Regorafenib Effects in Human Hepatocellular Carcinoma Cells

Refolo, M. G., Lippolis, C., Carella, N., Cavallini, A., Messa, C. & D'Alessandro, R., May 19 2018, In : International Journal of Molecular Sciences. 19, 5, p. 1518 16 p.

Research output: Contribution to journalArticle

Chlorogenic Acid
Hepatocellular Carcinoma
cancer
Cells
acids

Strong enhancement by IGF1-R antagonists of hepatocellular carcinoma cell migration inhibition by Sorafenib and/or vitamin K1

D'Alessandro, R., Refolo, M. G., Lippolis, C., Carella, N., Messa, C., Cavallini, A. & Carr, B. I., Jun 2018, In : Cellular oncology (Dordrecht). 41, 3, p. 283-296 14 p.

Research output: Contribution to journalArticle

Cell Migration Inhibition
Vitamin K 1
Somatomedins
Hepatocellular Carcinoma
Cell Movement
2017
4 Citations (Scopus)

IGF-1R tyrosine kinase inhibitors and Vitamin K1 enhance the antitumor effects of Regorafenib in HCC cell lines

Refolo, M. G., D'Alessandro, R., Lippolis, C., Carella, N., Cavallini, A., Messa, C. & Carr, B. I., Nov 28 2017, In : Oncotarget. 8, 61, p. 103465-103476 12 p.

Research output: Contribution to journalArticle

Vitamin K 1
Protein-Tyrosine Kinases
Cell Line
Cell Movement
Vitamin K
2015
42 Citations (Scopus)

Anti Proliferative and Pro Apoptotic Effects of Flavonoid Quercetin Are Mediated by CB1 Receptor in Human Colon Cancer Cell Lines

Refolo, M. G., D'Alessandro, R., Malerba, N., Laezza, C., Bifulco, M., Messa, C., Caruso, M. G., Notarnicola, M. & Tutino, V., Dec 1 2015, In : Journal of Cellular Physiology. 230, 12, p. 2973-2980 8 p.

Research output: Contribution to journalArticle

Cannabinoid Receptor CB1
Quercetin
Flavonoids
Colonic Neoplasms
Cells
9 Citations (Scopus)

Modulation of Regorafenib effects on HCC cell lines by epidermal growth factor

D'Alessandro, R., Refolo, M. G., Lippolis, C., Carella, N., Messa, C., Cavallini, A. & Carr, B. I., Apr 24 2015, In : Cancer Chemotherapy and Pharmacology. 75, 6, p. 1237-1245 9 p.

Research output: Contribution to journalArticle

Epidermal Growth Factor
Hepatocellular Carcinoma
Cells
Modulation
Cell Line
5 Citations (Scopus)
Platelet Aggregation Inhibitors
Neoplasms
Drug Therapy
Blood Platelets
Growth Inhibitors
11 Citations (Scopus)

Resistance to multikinase inhibitor actions mediated by insulin like growth factor-1

Lippolis, C., Refolo, M. G., D'Alessandro, R., Carella, N., Messa, C., Cavallini, A. & Carr, B. I., Sep 2 2015, In : Journal of Experimental and Clinical Cancer Research. 34, 1, 90.

Research output: Contribution to journalArticle

Somatomedins
Hepatocellular Carcinoma
Growth
Apoptosis
Cell Movement
2014
17 Citations (Scopus)

Antagonism of Sorafenib and Regorafenib actions by platelet factors in hepatocellular carcinoma cell lines

D'Alessandro, R., Refolo, M. G., Lippolis, C., Giannuzzi, G., Carella, N., Messa, C., Cavallini, A. & Carr, B. I., May 21 2014, In : BMC Cancer. 14, 1, 351.

Research output: Contribution to journalArticle

Hepatocellular Carcinoma
Blood Platelets
Cell Line
Apoptosis
Growth
3 Citations (Scopus)

Modulation of doxorubicin mediated growth inhibition of hepatocellular carcinoma cells by platelet lysates

Refolo, M. G., D’Alessandro, R., Lippolis, C., Messa, C., Carella, N., Cavallini, A. & Carr, B. I., Sep 1 2014, In : Anti-Cancer Agents in Medicinal Chemistry. 14, 8, p. 1154-1164 11 p.

Research output: Contribution to journalArticle

Doxorubicin
Hepatocellular Carcinoma
Blood Platelets
Apoptosis
Growth
1 Citation (Scopus)

N6-isopentenyladenosine inhibits cell proliferation and induces apoptosis in a human colon cancer cell line DLD1 (Int J Cancer. (2009) 124, 6 (1322-1329) DOI: 10.1002/ijc.24056)

Laezza, C., Caruso, M. G., Gentile, T., Notarnicola, M., Malfitano, A. M., Di Matola, T., Messa, C., Gazzerro, P. & Bifulco, M., Nov 15 2014, In : International Journal of Cancer. 135, 10

Research output: Contribution to journalArticle

52 Citations (Scopus)

Platelet extracts induce growth, migration and invasion in human hepatocellular carcinoma in vitro

Carr, B. I., Cavallini, A., D'Alessandro, R., Refolo, M. G., Lippolis, C., Mazzocca, A. & Messa, C., Jan 27 2014, In : BMC Cancer. 14, 1, 43.

Research output: Contribution to journalArticle

Hepatocellular Carcinoma
Blood Platelets
Growth
Cell Line
Thrombocytosis
2013
31 Citations (Scopus)

Effects of low concentrations of Regorafenib and Sorafenib on human HCC cell AFP, migration, invasion, and growth in vitro

Carr, B. I., D'Alessandro, R., Refolo, M. G., Iacovazzi, P. A., Lippolis, C., Messa, C., Cavallini, A., Correale, M. & Di Carlo, A., Jun 2013, In : Journal of Cellular Physiology. 228, 6, p. 1344-1350 7 p.

Research output: Contribution to journalArticle

alpha-Fetoproteins
Hepatocellular Carcinoma
Growth
Pharmaceutical Preparations
Cell growth
39 Citations (Scopus)

Fluoro-Sorafenib (Regorafenib) effects on hepatoma cells: Growth inhibition, quiescence, and recovery

Carr, B. I., Cavallini, A., Lippolis, C., D'Alessandro, R., Messa, C., Refolo, M. G. & Tafaro, A., Feb 2013, In : Journal of Cellular Physiology. 228, 2, p. 292-297 6 p.

Research output: Contribution to journalArticle

Cell growth
Hepatocellular Carcinoma
Recovery
Growth
Pharmaceutical Preparations
9 Citations (Scopus)

Reversibility of regorafenib effects in hepatocellular carcinoma cells

D'Alessandro, R., Refolo, M. G., Lippolis, C., Messa, C., Cavallini, A., Rossi, R., Resta, L., Di Carlo, A. & Carr, B. I., Oct 2013, In : Cancer Chemotherapy and Pharmacology. 72, 4, p. 869-877 9 p.

Research output: Contribution to journalArticle

Cell growth
Hepatocellular Carcinoma
Cells
Growth
Recovery
2012
24 Citations (Scopus)

Antiproliferative, antioxidant and anti-inflammatory effects of hydroxytyrosol on human hepatoma HepG2 and Hep3B cell lines

Tutino, V., Caruso, M. G., Messa, C., Perri, E. & Notarnicola, M., Dec 2012, In : Anticancer Research. 32, 12, p. 5371-5377 7 p.

Research output: Contribution to journalArticle

Hep G2 Cells
Hepatocellular Carcinoma
Anti-Inflammatory Agents
Antioxidants
Cell Line
47 Citations (Scopus)
Lactobacillus rhamnosus
Stomach
Colon
Hot Temperature
Stomach Neoplasms
18 Citations (Scopus)

A significant role of lipogenic enzymes in colorectal cancer

Notarnicola, M., Messa, C. & Caruso, M. G., Jul 2012, In : Anticancer Research. 32, 7, p. 2585-2590 6 p.

Research output: Contribution to journalArticle

Fatty Acid Synthases
Colorectal Neoplasms
Farnesyltranstransferase
Enzymes
Neoplasms
2011
36 Citations (Scopus)
Fatty Acid Synthases
Eicosapentaenoic Acid
Hep G2 Cells
Unsaturated Fatty Acids
Gene expression
2010
26 Citations (Scopus)

Effects of anandamide on polyamine levels and cell growth in human colon cancer cells

Linsalata, M., Notarnicola, M., Tutino, V., Bifulco, M., Santoro, A., Laezza, C., Messa, C., Orlando, A. & Caruso, M. G., Jul 2010, In : Anticancer Research. 30, 7, p. 2583-2589 7 p.

Research output: Contribution to journalArticle

Polyamines
Colonic Neoplasms
Growth
HT29 Cells
Cell Proliferation
23 Citations (Scopus)
Lactobacillus rhamnosus
Chemoprevention
Polyamines
Stomach Neoplasms
Probiotics
27 Citations (Scopus)
Quercetin
Polyamines
Colonic Neoplasms
Ornithine Decarboxylase
Apoptosis
30 Citations (Scopus)
Lovastatin
Eicosapentaenoic Acid
LDL Receptors
Hep G2 Cells
Gene expression
21 Citations (Scopus)

Synergistic inhibition of human colon cancer cell growth by the cannabinoid CB1 receptor antagonist rimonabant and oxaliplatin

Gazzerro, P., Malfitano, A. M., Proto, M. C., Santoro, A., Pisanti, S., Caruso, M. G., Notarnicola, M., Messa, C., Laezza, C., Misso, G., Caraglia, M. & Bifulco, M., 2010, In : Oncology Reports. 23, 1, p. 171-175 5 p.

Research output: Contribution to journalArticle

oxaliplatin
rimonabant
Cannabinoid Receptor Antagonists
Colonic Neoplasms
Growth
2009
43 Citations (Scopus)
Lactobacillus rhamnosus
Polyamines
Metabolism
Colonic Neoplasms
Stomach
31 Citations (Scopus)

N6-isopentenyladenosine Inhibits cell proliferation and Induces apoptosis In a human colon cancer cell line DLD1

Laezza, C., Caruso, M. G., Gentile, T., Notarmicola, M., Malfitano, A. M., Di Matola, T., Messa, C., Gazzerro, P. & Bifulco, M., Mar 15 2009, In : International Journal of Cancer. 124, 6, p. 1322-1329 8 p.

Research output: Contribution to journalArticle

Isopentenyladenosine
Colonic Neoplasms
Cell Proliferation
Apoptosis
Cell Line
2008
8 Citations (Scopus)

Early induction of LDL receptor gene expression by genistein in DLD-1 colon cancer cell line

Caruso, M. G., Messa, C., Orlando, A., D'Attoma, B. & Notarnicola, M., Dec 2008, In : Fitoterapia. 79, 7-8, p. 524-528 5 p.

Research output: Contribution to journalArticle

Genistein
LDL Receptors
Colonic Neoplasms
Oxidoreductases
Gene Expression
8 Citations (Scopus)

Effect of genistein on cholesterol metabolism-related genes in a colon cancer cell line

Notarnicola, M., Messa, C., Orlando, A., D'Attoma, B., Tutino, V., Rivizzigno, R. & Caruso, M. G., 2008, In : Genes and Nutrition. 3, 1, p. 35-40 6 p.

Research output: Contribution to journalArticle

Hydroxymethylglutaryl CoA Reductases
Genistein
LDL Receptors
Colonic Neoplasms
Cholesterol
29 Citations (Scopus)

Estrogenic induction of cannabinoid CB1 receptor in human colon cancer cell lines

Notarnicola, M., Messa, C., Orlando, A., Bifulco, M., Laezza, C., Gazzerro, P. & Caruso, M. G., 2008, In : Scandinavian Journal of Gastroenterology. 43, 1, p. 66-72 7 p.

Research output: Contribution to journalArticle

Cannabinoid Receptor CB1
Colonic Neoplasms
Cell Line
Estradiol
HT29 Cells
2007
24 Citations (Scopus)
Lactobacillus rhamnosus
stomach neoplasms
Polyamines
polyamines
Stomach Neoplasms
2006
41 Citations (Scopus)

N6-isopentenyladenosine arrests tumor cell proliferation by inhibiting farnesyl diphosphate synthase and protein prenylation

Laezza, C., Notarnicola, M., Caruso, M. G., Messa, C., Macchia, M., Bertini, S., Minutolo, F., Portella, G., Fiorentino, L., Stingo, S. & Bifulco, M., Mar 2006, In : FASEB Journal. 20, 3, p. 412-418 7 p.

Research output: Contribution to journalArticle

Isopentenyladenosine
Geranyltranstransferase
Protein Prenylation
Cell proliferation
Tumors
2005
24 Citations (Scopus)
Genistein
genistein
Polyamines
polyamines
colorectal neoplasms
24 Citations (Scopus)

Estrogenic regulation of cholesterol biosynthesis and cell growth in DLD-1 human colon cancer cells

Messa, C., Notarnicola, M., Russo, F., Cavallini, A., Pallottini, V., Trentalance, A., Bifulco, M., Laezza, C. & Caruso, M. G., Dec 2005, In : Scandinavian Journal of Gastroenterology. 40, 12, p. 1454-1461 8 p.

Research output: Contribution to journalArticle

LDL Receptors
Colonic Neoplasms
Coenzyme A
Oxidoreductases
Cholesterol
2004
34 Citations (Scopus)

Higher farnesyl diphosphate synthase activity in human colorectal cancer inhibition of cellular apoptosis.

Notarnicola, M., Messa, C., Cavallini, A., Bifulco, M., Tecce, M. F., Eletto, D., Di Leo, A., Montemurro, S., Laezza, C. & Caruso, M. G., 2004, In : Oncology. 67, 5-6, p. 351-358 8 p.

Research output: Contribution to journalArticle

Geranyltranstransferase
pamidronate
Human Activities
Colorectal Neoplasms
Apoptosis
50 Citations (Scopus)

Up-regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity in left-sided human colon cancer

Notarnicola, M., Messa, C., Pricci, M., Guerra, V., Altomare, D. F., Montemurro, S. & Caruso, M. G., Nov 2004, In : Anticancer Research. 24, 6, p. 3837-3842 6 p.

Research output: Contribution to journalArticle

Colonic Neoplasms
Oxidoreductases
Up-Regulation
LDL Receptors
Simvastatin
2003
40 Citations (Scopus)

Helicobacter pylori is associated with modified lipid profile: Impact on Lipoprotein(a)

Chimienti, G., Russo, F., Lamanuzzi, B. L., Nardulli, M., Messa, C., Di Leo, A., Correale, M., Giannuzzi, V. & Pepe, G., Jul 2003, In : Clinical Biochemistry. 36, 5, p. 359-365 7 p.

Research output: Contribution to journalArticle

Lipoprotein(a)
Cytotoxins
Helicobacter pylori
Genes
Lipids
2002
23 Citations (Scopus)

Distribution of estrogen receptor subtypes, expression of their variant forms, and clinicopathological characteristics of human colorectal cancer

Cavallini, A., Messa, C., Pricci, M., Caruso, M. L., Barone, M. & Di Leo, A., Dec 1 2002, In : Digestive Diseases and Sciences. 47, 12, p. 2720-2728 9 p.

Research output: Contribution to journalArticle

Estrogen Receptors
Colorectal Neoplasms
Messenger RNA
Protein Isoforms
Exons
2001
44 Citations (Scopus)

Circulating cytokines and gastrin levels in asymptomatic subjects infected by Helicobacter pylori (H. pylori)

Russo, F., Jirillo, E., Clemente, C., Messa, C., Chiloiro, M., Riezzo, G., Amati, L., Caradonna, L., Leo, A. D. & Leo, A. D., 2001, In : Immunopharmacology and Immunotoxicology. 23, 1, p. 13-24 12 p.

Research output: Contribution to journalArticle

Gastrins
Helicobacter pylori
Interleukin-8
Interleukin-10
Interferons
20 Citations (Scopus)

Effect of Helicobacter pylori infection on gastric emptying and gastrointestinal hormones in dyspeptic and healthy subjects

Chiloiro, M., Russo, F., Riezzo, G., Leoci, C., Clemente, C., Messa, C. & Di Leo, A., 2001, In : Digestive Diseases and Sciences. 46, 1, p. 46-53 8 p.

Research output: Contribution to journalArticle

Gastrointestinal Hormones
Gastric Emptying
Helicobacter Infections
Helicobacter pylori
Healthy Volunteers
16 Citations (Scopus)

Effects of 17β-estradiol administration on apoptosis and polyamine content in AGS cell line

Pricci, M., Linsalata, M., Russo, F., Messa, C., Amati, L., Caradonna, L., Jirillo, E. & Di Leo, A., 2001, In : Anticancer Research. 21, 5, p. 3215-3220 6 p.

Research output: Contribution to journalArticle

Polyamines
Estradiol
Apoptosis
Cell Line
Spermine
72 Citations (Scopus)

Estrogens and colorectal cancer.

Di Leo, A., Messa, C., Cavallini, A. & Linsalata, M., May 2001, In : Current Drug Targets: Immune, Endocrine and Metabolic Disorders. 1, 1, p. 1-12 12 p.

Research output: Contribution to journalArticle

Estrogen Receptors
Colorectal Neoplasms
Estrogens
Colonic Neoplasms
Dimethylhydrazines
21 Citations (Scopus)

Oestrogen receptors and microsatellite instability in colorectal carcinoma patients

Notarnicola, M., Gristina, R., Messa, C., Cariola, F., Fiorente, P., Caruso, M. L., Gentile, M. & Di Leo, A., Jul 10 2001, In : Cancer Letters. 168, 1, p. 65-70 6 p.

Research output: Contribution to journalArticle

Microsatellite Instability
Estrogen Receptors
Colorectal Neoplasms
Estrogens
Neoplasms
2000
22 Citations (Scopus)

Epidermal growth factor and 17β-estradiol effects on proliferation of a human gastric cancer cell line (AGS)

Messa, C., Russo, F., Pricci, M. & Di Leo, A., 2000, In : Scandinavian Journal of Gastroenterology. 35, 7, p. 753-758 6 p.

Research output: Contribution to journalArticle

Epidermal Growth Factor
Stomach Neoplasms
Estradiol
Cell Line
Estrogens
1999
15 Citations (Scopus)

Helicobacter pylori infection and host cell responses

Di Leo, A., Messa, C., Russo, F., Linsalata, M., Amati, L., Caradonna, L., Pece, S., Pellegrino, N. M., Caccavo, D., Antonaci, S. & Jirillo, E., 1999, In : Immunopharmacology and Immunotoxicology. 21, 4, p. 803-846 44 p.

Research output: Contribution to journalArticle

Polyamines
Helicobacter Infections
Helicobacter pylori
Carcinogens
Lipopolysaccharides
19 Citations (Scopus)
Polyamines
Estradiol
Stomach
Carcinoma
Cell Line
6 Citations (Scopus)

The role of Helicobacter pylori LPS in the pathogenesis of H. pylori-related gastropathy

Jirillo, E., Pece, S., Pellegrino, N. M., Di Leo, A., Russo, F., Linsalata, M., Messa, C., Amati, L., Caradonna, L., Moran, A. P. & Caccavo, D., 1999, In : Journal of Endotoxin Research. 5, 4, p. 222-226 5 p.

Research output: Contribution to journalArticle

Helicobacter pylori
Lipopolysaccharides
Gastritis
Duodenal Ulcer
Signal transduction

The role of Helicobacter pylori LPS in the pathogenesis of H. pylori-related gastropathy

Jirillo, E., Pece, S., Pellegrino, N. M., Di Leo, A., Russo, F., Linsalata, M., Messa, C., Amati, L., Caradonna, L., Moran, A. P. & Caccavo, D., 1999, In : Innate Immunity. 5, 4, p. 222-226 5 p.

Research output: Contribution to journalArticle

Helicobacter pylori
Gastritis
Duodenal Ulcer
Lipopolysaccharides
Gastrointestinal Contents
1998
218 Citations (Scopus)

EGF, TGF-α, and EGF-R in human colorectal adenocarcinoma

Messa, C., Russo, F., Caruso, M. G. & Di Leo, A., 1998, In : Acta Oncologica. 37, 3, p. 285-289 5 p.

Research output: Contribution to journalArticle

Transforming Growth Factor alpha
Epidermal Growth Factor Receptor
Epidermal Growth Factor
Adenocarcinoma
Mucous Membrane