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2019

Comparative assessment of antitumor effects and autophagy induction as a resistance mechanism by cytotoxics and EZH2 inhibition in INI1-negative epithelioid sarcoma patient-derived xenograft

Stacchiotti, S., Zuco, V., Tortoreto, M., Cominetti, D., Frezza, A. M., Percio, S., Indio, V., Barisella, M., Monti, V., Brich, S., Astolfi, A., Colombo, C., Pasquali, S., Folini, M., Gounder, M. M., Pantaleo, M. A., Collini, P., Tos, A. P. D., Casali, P. G., Gronchi, A. & 1 others, Zaffaroni, N., Jul 2019, In : Cancers. 11, 7, 1015.

Research output: Contribution to journalArticle

Open Access

The Prognostic Role of β-Catenin Mutations in Desmoid-type Fibromatosis Undergoing Resection Only: A Meta-analysis of Individual Patient Data

Timbergen, M. J. M., Colombo, C., Renckens, M., Kim, H. S., Rosmalen, J. V., Salas, S., Mullen, J. T., Colombo, P., Nishida, Y., Wiemer, E. A. C., Verhoef, C., Sleijfer, S., Gronchi, A. & Grünhagen, D. J., Dec 2 2019, In : Annals of Surgery.

Research output: Contribution to journalArticle

2018

Botulinum toxin type A affects the transcriptome of cell cultures derived from muscle biopsies of controls and spastic patients

Zanotti, S., Kapetis, D., Gibertini, S., Salerno, F., Ciusani, E., Colombo, C., Gronchi, A., Morandi, L., Mantegazza, R., Molteni, F. & Mora, M., Aug 1 2018, In : Toxicology in Vitro. 50, p. 124-136 13 p.

Research output: Contribution to journalArticle

High-risk soft tissue sarcomas treated with perioperative chemotherapy: Improving prognostic classification in a randomised clinical trial

Pasquali, S., Colombo, C., Pizzamiglio, S., Verderio, P., Callegaro, D., Stacchiotti, S., Martin Broto, J., Lopez-Pousa, A., Ferrari, S., Poveda, A., De Paoli, A., Quagliuolo, V., Jurado, J. C., Comandone, A., Grignani, G., De Sanctis, R., Palassini, E., Llomboart-Bosch, A., Dei Tos, A. P., Casali, P. G. & 2 others, Picci, P. & Gronchi, A., Apr 2018, In : European Journal of Cancer. 93, p. 28-36 9 p.

Research output: Contribution to journalArticle

High-risk soft tissue sarcomas treated with perioperative chemotherapy: Improving prognostic classification in a randomised clinical trial

Pasquali, S., Colombo, C., Pizzamiglio, S., Verderio, P., Callegaro, D., Stacchiotti, S., Martin Broto, J., Lopez-Pousa, A., Ferrari, S., Poveda, A., De Paoli, A., Quagliuolo, V., Jurado, J. C., Comandone, A., Grignani, G., De Sanctis, R., Palassini, E., Llomboart-Bosch, A., Dei Tos, A. P., Casali, P. G. & 2 others, Picci, P. & Gronchi, A., Apr 1 2018, In : European Journal of Cancer. 93, p. 28-36 9 p.

Research output: Contribution to journalArticle

Identification of an actionable mutation of kit in a case of extraskeletal myxoid chondrosarcoma

Urbini, M., Indio, V., Astolfi, A., Tarantino, G., Renne, S. L., Pilotti, S., Dei Tos, A. P., Maestro, R., Collini, P., Nannini, M., Saponara, M., Murrone, L., Dagrada, G. P., Colombo, C., Gronchi, A., Pession, A., Casali, P. G., Stacchiotti, S. & Pantaleo, M. A., Jul 1 2018, In : International Journal of Molecular Sciences. 19, 7, 1855.

Research output: Contribution to journalArticle

Identification of an Actionable Mutation of KIT in a Case of Extraskeletal Myxoid Chondrosarcoma

Urbini, M., Indio, V., Astolfi, A., Tarantino, G., Renne, S. L., Pilotti, S., Dei Tos, A. P., Maestro, R., Collini, P., Nannini, M., Saponara, M., Murrone, L., Dagrada, G. P., Colombo, C., Gronchi, A., Pession, A., Casali, P. G., Stacchiotti, S. & Pantaleo, M. A., Jun 23 2018, In : International Journal of Molecular Sciences. 19, 7

Research output: Contribution to journalArticle

Novel intra-genic large deletions of CTNNB1 gene identified in WT desmoid-type fibromatosis

Colombo, C., Urbini, M., Astolfi, A., Collini, P., Indio, V., Belfiore, A., Paielli, N., Perrone, F., Tarantino, G., Palassini, E., Fiore, M., Pession, A., Stacchiotti, S., Pantaleo, M. A. & Gronchi, A., Oct 2018, In : Genes Chromosomes and Cancer. 57, 10, p. 495-503 9 p.

Research output: Contribution to journalArticle

2017

Genome-wide analysis identifies MEN1 and MAX mutations and a neuroendocrine-like molecular heterogeneity in Quadruple WT GIST

Pantaleo, M. A., Urbini, M., Indio, V., Ravegnini, G., Nannini, M., De Luca, M., Tarantino, G., Angelini, S., Gronchi, A., Vincenzi, B., Grignani, G., Colombo, C., Fumagalli, E., Gatto, L., Saponara, M., Ianni, M., Paterini, P., Santini, D., Pirini, M. G., Ceccarelli, C. & 10 others, Altimari, A., Gruppioni, E., Renne, S. L., Collini, P., Stacchiotti, S., Brandi, G., Casali, P. G., Pinna, A. D., Astolfi, A. & Biasco, G., May 1 2017, In : Molecular Cancer Research. 15, 5, p. 553-562 10 p.

Research output: Contribution to journalArticle

Genome-Wide Analysis Identifies MEN1 and MAX Mutations and a Neuroendocrine-Like Molecular Heterogeneity in Quadruple WT GIST

Pantaleo, M. A., Urbini, M., Indio, V., Ravegnini, G., Nannini, M., De Luca, M., Tarantino, G., Angelini, S., Gronchi, A., Vincenzi, B., Grignani, G., Colombo, C., Fumagalli, E., Gatto, L., Saponara, M., Ianni, M., Paterini, P., Santini, D., Pirini, M. G., Ceccarelli, C. & 10 others, Altimari, A., Gruppioni, E., Renne, S. L., Collini, P., Stacchiotti, S., Brandi, G., Casali, P. G., Pinna, A. D., Astolfi, A. & Biasco, G., May 2017, In : Molecular Cancer Research. 15, 5, p. 553-562 10 p.

Research output: Contribution to journalArticle

HSPA8 as a novel fusion partner of NR4A3 in extraskeletal myxoid chondrosarcoma

Urbini, M., Astolfi, A., Pantaleo, M. A., Serravalle, S., Dei Tos, A. P., Picci, P., Indio, V., Sbaraglia, M., Benini, S., Righi, A., Gambarotti, M., Gronchi, A., Colombo, C., Dagrada, G. P., Pilotti, S., Maestro, R., Polano, M., Saponara, M., Tarantino, G., Pession, A. & 3 others, Biasco, G., Casali, P. G. & Stacchiotti, S., 2017, In : Genes Chromosomes and Cancer. 56, 7, p. 582-586 5 p.

Research output: Contribution to journalArticle

HSPA8 as a novel fusion partner of NR4A3 in extraskeletal myxoid chondrosarcoma

Urbini, M., Astolfi, A., Pantaleo, M. A., Serravalle, S., Dei Tos, A. P., Picci, P., Indio, V., Sbaraglia, M., Benini, S., Righi, A., Gambarotti, M., Gronchi, A., Colombo, C., Dagrada, G. P., Pilotti, S., Maestro, R., Polano, M., Saponara, M., Tarantino, G., Pession, A. & 3 others, Biasco, G., Casali, P. G. & Stacchiotti, S., Jul 1 2017, In : Genes Chromosomes and Cancer. 56, 7, p. 582-586 5 p.

Research output: Contribution to journalArticle

HSPA8 as a novel fusion partner of NR4A3 in extraskeletal myxoid chondrosarcoma

Urbini, M., Astolfi, A., Pantaleo, M. A., Serravalle, S., Dei Tos, A. P., Picci, P., Indio, V., Sbaraglia, M., Benini, S., Righi, A., Gambarotti, M., Gronchi, A., Colombo, C., Dagrada, G. P., Pilotti, S., Maestro, R., Polano, M., Saponara, M., Tarantino, G., Pession, A. & 3 others, Biasco, G., Casali, P. G. & Stacchiotti, S., Jul 1 2017, In : Genes Chromosomes and Cancer. 56, 7, p. 582-586 5 p.

Research output: Contribution to journalArticle

β-Catenin in desmoid-type fibromatosis: deep insights into the role of T41A and S45F mutations on protein structure and gene expression

Colombo, C., Belfiore, A., Paielli, N., De Cecco, L., Canevari, S., Laurini, E., Fermeglia, M., Pricl, S., Verderio, P., Bottelli, S., Fiore, M., Stacchiotti, S., Palassini, E., Gronchi, A., Pilotti, S. & Perrone, F., Nov 1 2017, In : Molecular Oncology. 11, 11, p. 1495-1507 13 p.

Research output: Contribution to journalArticle

2016

AKT1 and BRAF mutations in pediatric aggressive fibromatosis

Meazza, C., Belfiore, A., Busico, A., Settanni, G., Paielli, N., Cesana, L., Ferrari, A., Chiaravalli, S., Massimino, M., Gronchi, A., Colombo, C., Pilotti, S. & Perrone, F., Jun 1 2016, In : Cancer Medicine. 5, 6, p. 1204-1213 10 p.

Research output: Contribution to journalArticle

Evolution of dermatofibrosarcoma protuberans to DFSP-derived fibrosarcoma: An event marked by epithelial-mesenchymal transition-like process and 22q loss

Stacchiotti, S., Astolfi, A., Gronchi, A., Fontana, A., Pantaleo, M. A., Negri, T., Brenca, M., Tazzari, M., Urbini, M., Indio, V., Colombo, C., Radaelli, S., Brich, S., Tos, A. P. D., Casali, P. G., Castelli, C., Dagrada, G. P., Pilotti, S. & Maestro, R., Sep 1 2016, In : Molecular Cancer Research. 14, 9, p. 820-829 10 p.

Research output: Contribution to journalArticle

Evolution of dermatofibrosarcoma protuberans to DFSP-derived fibrosarcoma: An event marked by epithelial-mesenchymal transition-like process and 22q loss

Stacchiotti, S., Astolfi, A., Gronchi, A., Fontana, A., Pantaleo, M. A., Negri, T., Brenca, M., Tazzari, M., Urbini, M., Indio, V., Colombo, C., Radaelli, S., Brich, S., Tos, A. P. D., Casali, P. G., Castelli, C., Dagrada, G. P., Pilotti, S. & Maestro, R., Sep 1 2016, In : Molecular Cancer Research. 14, 9, p. 820-829 10 p.

Research output: Contribution to journalArticle

Evolution of dermatofibrosarcoma protuberans to DFSP-derived fibrosarcoma: An event marked by epithelial-mesenchymal transition-like process and 22q loss

Stacchiotti, S., Astolfi, A., Gronchi, A., Fontana, A., Pantaleo, M. A., Negri, T., Brenca, M., Tazzari, M., Urbini, M., Indio, V., Colombo, C., Radaelli, S., Brich, S., Tos, A. P. D., Casali, P. G., Castelli, C., Dagrada, G. P., Pilotti, S. & Maestro, R., Sep 1 2016, In : Molecular Cancer Research. 14, 9, p. 820-829 10 p.

Research output: Contribution to journalArticle

Tailored Beta-catenin mutational approach in extra-abdominal sporadic desmoid tumor patients without therapeutic intervention

van Broekhoven, D. L. M., Grünhagenl, D. J., van Dalen, T., van Coevorden, F., Bonenkamp, H. J., Been, L. B., Bemelmans, M. H. A., Dijkstra, S. D. S., Colombo, C., Gronchi, A. & Verhoef, C., Aug 26 2016, In : BMC Cancer. 16, 1, 686.

Research output: Contribution to journalArticle

2015

Hormonal manipulation with toremifene in sporadic desmoid-type fibromatosis

Fiore, M., Colombo, C., Radaelli, S., Callegaro, D., Palassini, E., Barisella, M., Morosi, C., Baldi, G. G., Stacchiotti, S., Casali, P. G. & Gronchi, A., Dec 1 2015, In : European Journal of Cancer. 51, 18, p. 2800-2807 8 p.

Research output: Contribution to journalArticle

Long-term morbidity after multivisceral resection for retroperitoneal sarcoma

Callegaro, D., Miceli, R., Brunelli, C., Colombo, C., Sanfilippo, R., Radaelli, S., Casali, P. G., Caraceni, A., Gronchi, A. & Fiore, M., Aug 1 2015, In : British Journal of Surgery. 102, 9, p. 1079-1087 9 p.

Research output: Contribution to journalArticle

Melan-A/MART-1 immunity in a EWS-ATF1 translocated clear cell sarcoma patient treated with sunitinib: A case report

Tazzari, M., Palassini, E., Vergani, B., Villa, A., Rini, F., Negri, T., Colombo, C., Crippa, F., Morosi, C., Casali, P. G., Pilotti, S., Stacchiotti, S., Rivoltini, L. & Castelli, C., Feb 14 2015, In : BMC Cancer. 15, 1, 58.

Research output: Contribution to journalArticle

Personalizing the Approach to Retroperitoneal Soft Tissue Sarcoma: Histology-specific Patterns of Failure and Postrelapse Outcome after Primary Extended Resection

Gronchi, A., Miceli, R., Allard, M. A., Callegaro, D., Le Péchoux, C., Fiore, M., Honoré, C., Sanfilippo, R., Coppola, S., Stacchiotti, S., Terrier, P., Casali, P. G., Le Cesne, A., Mariani, L., Colombo, C. & Bonvalot, S., May 1 2015, In : Annals of Surgical Oncology. 22, 5, p. 1447-1454 8 p.

Research output: Contribution to journalArticle

Sporadic extra abdominal wall desmoid-type fibromatosis: Surgical resection can be safely limited to a minority of patients

Colombo, C., Miceli, R., Le Péchoux, C., Palassini, E., Honoré, C., Stacchiotti, S., Mir, O., Casali, P. G., Dômont, J., Fiore, M., Le Cesne, A., Gronchi, A. & Bonvalot, S., 2015, In : European Journal of Cancer. 51, 2, p. 186-192 7 p.

Research output: Contribution to journalArticle

2014

Activity of sunitinib in extraskeletal myxoid chondrosarcoma

Stacchiotti, S., Pantaleo, M. A., Astolfi, A., Dagrada, G. P., Negri, T., Dei Tos, A. P., Indio, V., Morosi, C., Gronchi, A., Colombo, C., Conca, E., Toffolatti, L., Tazzari, M., Crippa, F., Maestro, R., Pilotti, S. & Casali, P. G., 2014, In : European Journal of Cancer. 50, 9, p. 1657-1664 8 p.

Research output: Contribution to journalArticle

Coronary spasm under combined epidural-general anesthesia. Case report

Previtali, P., Fumagalli, L., Ammatuna, M., Materazzo, C., Colombo, C. & Langer, M., 2014, In : Experimental and Clinical Cardiology. 20, 1, p. 1997-1999 3 p.

Research output: Contribution to journalArticle

Desmoid-type fibromatosis and pregnancy: A multi-institutional analysis of recurrence and obstetric risk

Fiore, M., Coppola, S., Cannell, A. J., Colombo, C., Bertagnolli, M. M., George, S., Le Cesne, A., Gladdy, R. A., Casali, P. G., Swallow, C. J., Gronchi, A., Bonvalot, S. & Raut, C. P., 2014, In : Annals of Surgery. 259, 5, p. 973-978 6 p.

Research output: Contribution to journalArticle

Prognostic Factors and Outcome of Spermatic Cord Sarcoma

Radaelli, S., Desai, A., Hodson, J., Colombo, C., Roberts, K., Gourevitch, D. & Gronchi, A., Oct 1 2014, In : Annals of Surgical Oncology. 21, 11, p. 3557-3563 7 p.

Research output: Contribution to journalArticle

Sporadic desmoid-type fibromatosis: A stepwise approach to a non-metastasising neoplasm-A position paper from the Italian and the French Sarcoma Group

Gronchi, A., Colombo, C., Le Péchoux, C., Dei Tos, A. P., Le Cesne, A., Marrari, A., Penel, N., Grignani, G., Blay, J. Y., Casali, P. G., Stoeckle, E., Gherlinzoni, F., Meeus, P., Mussi, C., Gouin, F., Duffaud, F., Fiore, M. & Bonvalot, S., Mar 2014, In : Annals of Oncology. 25, 3, p. 578-583 6 p., mdt485.

Research output: Contribution to journalArticle

Surgical management of localized soft tissue tumors

Gronchi, A., Colombo, C. & Raut, C. P., Sep 1 2014, In : Cancer. 120, 17, p. 2638-2648 11 p.

Research output: Contribution to journalArticle

2013

CTNNB1 45F mutation is a molecular prognosticator of increased postoperative primary desmoid tumor recurrence: An independent, multicenter validation study

Colombo, C., Miceli, R., Lazar, A. J., Perrone, F., Pollock, R. E., Le Cesne, A., Hartgrink, H. H., Cleton-Jansen, A. M., Domont, J., Bovée, J. V. M. G., Bonvalot, S., Lev, D. & Gronchi, A., Oct 15 2013, In : Cancer. 119, 20, p. 3696-3702 7 p.

Research output: Contribution to journalArticle

Localized and metastatic myxoid/round cell liposarcoma: Clinical and molecular observations

Hoffman, A., Ghadimi, M. P. H., Demicco, E. G., Creighton, C. J., Torres, K., Colombo, C., Peng, T., Lusby, K., Ingram, D., Hornick, J. L., Wang, W. L., Ravi, V., Lazar, A. J., Lev, D. & Pollock, R. E., May 15 2013, In : Cancer. 119, 10, p. 1868-1877 10 p.

Research output: Contribution to journalArticle

Outcome prediction in primary resected retroperitoneal soft tissue sarcoma: histology-specific overall survival and disease-free survival nomograms built on major sarcoma center data sets.

Gronchi, A., Miceli, R., Shurell, E., Eilber, F. C., Eilber, F. R., Anaya, D. A., Kattan, M. W., Honoré, C., Lev, D. C., Colombo, C., Bonvalot, S., Mariani, L. & Pollock, R. E., May 1 2013, In : Journal of Clinical Oncology. 31, 13, p. 1649-1655 7 p.

Research output: Contribution to journalArticle

Spontaneous regression of primary abdominal wall desmoid tumors: More common than previously thought

Bonvalot, S., Ternes, N., Fiore, M., Bitsakou, G., Colombo, C., Honore, C., Marrari, A., Cesne, A. L., Perrone, F., Dunant, A. & Gronchi, A., 2013, In : Annals of Surgical Oncology. 20, 13, p. 4096-4102 7 p.

Research output: Contribution to journalArticle

Uterine leiomyosarcoma management, outcome, and associated molecular biomarkers: A single institution's experience

Lusby, K., Savannah, K. B., Demicco, E. G., Zhang, Y., Ghadimi, M. P., Young, E. D., Colombo, C., Lam, R., Dogan, T. E., Hornick, J. L., Lazar, A. J., Hunt, K. K., Anderson, M. L., Creighton, C. J., Lev, D. & Pollock, R. E., Jul 2013, In : Annals of Surgical Oncology. 20, 7, p. 2364-2372 9 p.

Research output: Contribution to journalArticle

2012

Clinical, pathological and surgical characteristics of duodenal gastrointestinal stromal tumor and their influence on survival: A multi-center study

Colombo, C., Ronellenfitsch, U., Yuxin, Z., Rutkowski, P., Miceli, R., Bylina, E., Hohenberger, P., Raut, C. P. & Gronchi, A., Oct 2012, In : Annals of Surgical Oncology. 19, 11, p. 3361-3367 7 p.

Research output: Contribution to journalArticle

Critical Role of Heat Shock Protein 27 in Bufalin-Induced Apoptosis in Human Osteosarcomas: A Proteomic-Based Research

Xie, X. B., Yin, J. Q., Wen, L. L., Gao, Z. H., Zou, C. Y., Wang, J., Huang, G., Tang, Q. L., Colombo, C., He, W. L., Jia, Q. & Shen, J. N., Oct 16 2012, In : PLoS One. 7, 10, e47375.

Research output: Contribution to journalArticle