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Research Output 2004 2019

  • 4629 Citations
  • 38 h-Index
  • 166 Article
  • 5 Chapter
  • 3 Review article
2019

Cerebral perfusion changes in presymptomatic genetic frontotemporal dementia: A GENFI study

GENetic Frontotemporal dementia Initiative (GENFI) , 2019, In : Brain. 142, 4, p. 1108-1120 13 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Cerebrospinal Fluid Level of Aquaporin4: A New Window on Glymphatic System Involvement in Neurodegenerative Disease?

Arighi, A., Di Cristofori, A., Fenoglio, C., Borsa, S., D'Anca, M., Fumagalli, G. G., Locatelli, M., Carrabba, G., Pietroboni, A. M., Ghezzi, L., Carandini, T., Colombi, A., Scarioni, M., De Riz, M. A., Serpente, M., Rampini, P. M., Scarpini, E. & Galimberti, D., Jan 1 2019, In : Journal of Alzheimer's Disease. 69, 3, p. 663-669 7 p.

Research output: Contribution to journalArticle

Normal Pressure Hydrocephalus
Neurodegenerative Diseases
Cerebrospinal Fluid
Alzheimer Disease
Aquaporins

Exploring the role of BDNF DNA methylation and hydroxymethylation in patients with obsessive compulsive disorder

D'Addario, C., Bellia, F., Benatti, B., Grancini, B., Vismara, M., Pucci, M., De Carlo, V., Viganò, C., Galimberti, D., Fenoglio, C., Scarpini, E., Maccarrone, M. & Dell'Osso, B., Jul 1 2019, In : Journal of Psychiatric Research. 114, p. 17-23 7 p.

Research output: Contribution to journalArticle

Obsessive-Compulsive Disorder
Brain-Derived Neurotrophic Factor
DNA Methylation
Epigenomics
Exons

Genetic variation across RNA metabolism and cell death gene networks is implicated in the semantic variant of primary progressive aphasia

International FTD-Genomics Consortium (IFGC) , Dec 1 2019, In : Scientific Reports. 9, 1, 10854.

Research output: Contribution to journalArticle

Open Access
Primary Progressive Aphasia
Gene Regulatory Networks
Semantics
Cell Death
RNA
2 Citations (Scopus)

Identification of evolutionarily conserved gene networks mediating neurodegenerative dementia

International Frontotemporal Dementia Genomics Consortium, 2019, In : Nature Medicine. 25, 1, p. 152-164

Research output: Contribution to journalArticle

Gene Regulatory Networks
Dementia
Genes
MicroRNAs
Pharmaceutical Databases
1 Citation (Scopus)
Open Access
Apolipoprotein E4
Alzheimer Disease
Protein Isoforms
Oxidative Stress
Reactive Oxygen Species

Monozygotic Twins with Frontotemporal Dementia Due to Thr272fs GRN Mutation Discordant for Age at Onset

Fumagalli, G. G., Sacchi, L., Basilico, P., Arighi, A., Carandini, T., Scarioni, M., Colombi, A., Pietroboni, A., Ghezzi, L., Fenoglio, C., Serpente, M., D'Anca, M., Arcaro, M., Mercurio, M., Triulzi, F., Scola, E., Marotta, G., Scarpini, E. & Galimberti, D., Jan 1 2019, In : Journal of Alzheimer's Disease. 67, 4, p. 1173-1179 7 p.

Research output: Contribution to journalArticle

Frontotemporal Dementia
Monozygotic Twins
Age of Onset
Mutation
Leisure Activities
1 Citation (Scopus)

Spatiotemporal analysis for detection of pre-symptomatic shape changes in neurodegenerative diseases: Initial application to the GENFI cohort

Cury, C., Durrleman, S., Cash, D. M., Lorenzi, M., Nicholas, J. M., Bocchetta, M., van Swieten, J. C., Borroni, B., Galimberti, D., Masellis, M., Tartaglia, C., Rowe, J. B., Graff, C., Tagliavini, F., Frisoni, G. B., Laforce, R., Finger, E., de Mendonça, A., Sorbi, S., Ourselin, S. & 45 others, Rohrer, J. D., Modat, M., Andersson, C., Archetti, S., Arighi, A., Benussi, L., Black, S., Cosseddu, M., Fallstrm, M., Ferreira, C., Fenoglio, C., Fox, N., Freedman, M., Fumagalli, G., Gazzina, S., Ghidoni, R., Grisoli, M., Jelic, V., Jiskoot, L., Keren, R., Lombardi, G., Maruta, C., Meeter, L., van Minkelen, R., Nacmias, B., ijerstedt, L., Padovani, A., Panman, J., Pievani, M., Polito, C., Premi, E., Prioni, S., Rademakers, R., Redaelli, V., Rogaeva, E., Rossi, G., Rossor, M., Scarpini, E., Tang-Wai, D., Tartaglia, C., Thonberg, H., Tiraboschi, P., Verdelho, A., Warren, J. & GENFI1, G. FTD. I., Mar 2019, In : NeuroImage. 188, p. 282-290 9 p.

Research output: Contribution to journalArticle

Spatio-Temporal Analysis
Neurodegenerative Diseases
Atrophy
Thalamus
Frontotemporal Dementia
Alzheimer Disease
Cerebrospinal Fluid
Biomarkers
Amyloid
Positron-Emission Tomography
2018
5 Citations (Scopus)
Amyloid
Positron-Emission Tomography
Multiple Sclerosis
Cerebrospinal Fluid
Brain
11 Citations (Scopus)

Comparison of arterial spin labeling registration strategies in the multi-center GENetic frontotemporal dementia initiative (GENFI)

Mutsaerts, H. J. M. M., Petr, J., Thomas, D. L., De Vita, E., Cash, D. M., van Osch, M. J. P., Golay, X., Groot, P. F. C., Ourselin, S., van Swieten, J., Laforce, R., Tagliavini, F., Borroni, B., Galimberti, D., Rowe, J. B., Graff, C., Pizzini, F. B., Finger, E., Sorbi, S., Castelo Branco, M. & 31 others, Rohrer, J. D., Masellis, M., MacIntosh, B. J., Rossor, M., Fox, N., Warren, J., Bocchetta, M., Dick, K., Pievani, M., Ghidoni, R., Benussi, L., Padovani, A., Cosseddu, M., Mendonça, A., Frisoni, G., Premi, E., Archetti, S., Scarpini, E., Fumagalli, G., Arighi, A., Fenoglio, C., Prioni, S., Redaelii, V., Grisoli, M., Tiraboschi, P., Black, S., Rogaeva, E., Freedman, M., Tartaglia, M. C., Tang-Wai, D. & on behalf of the GENFI investigators, Jan 1 2018, In : Journal of Magnetic Resonance Imaging. 47, 1, p. 131-140 10 p.

Research output: Contribution to journalArticle

Cerebrovascular Circulation
Frontotemporal Dementia
Perfusion
Brain
Masks
1 Citation (Scopus)

CSF pro-orexin and amyloid-β38 expression in Alzheimer's disease and frontotemporal dementia

Heywood, W. E., Hallqvist, J., Heslegrave, A. J., Zetterberg, H., Fenoglio, C., Scarpini, E., Rohrer, J. D., Galimberti, D. & Mills, K., Dec 1 2018, In : Neurobiology of Aging. 72, p. 171-176 6 p.

Research output: Contribution to journalArticle

Frontotemporal Dementia
Amyloid
Alzheimer Disease
Chromosomes, Human, Pair 9
Open Reading Frames
10 Citations (Scopus)

CSF β-amyloid and white matter damage: A new perspective on Alzheimer's disease

Pietroboni, A. M., Scarioni, M., Carandini, T., Basilico, P., Cadioli, M., Giulietti, G., Arighi, A., Caprioli, M., Serra, L., Sina, C., Fenoglio, C., Ghezzi, L., Fumagalli, G. G., De Riz, M. A., Calvi, A., Triulzi, F., Bozzali, M., Scarpini, E. & Galimberti, D., Apr 1 2018, In : Journal of Neurology, Neurosurgery and Psychiatry. 89, 4, p. 352-357 6 p.

Research output: Contribution to journalArticle

Amyloid
Cerebrospinal Fluid
Alzheimer Disease
White Matter
Pathology
3 Citations (Scopus)

CSF β-amyloid predicts prognosis in patients with multiple sclerosis

Pietroboni, A. M., Caprioli, M., Carandini, T., Scarioni, M., Ghezzi, L., Arighi, A., Cioffi, S., Cinnante, C., Fenoglio, C., Oldoni, E., De Riz, M. A., Basilico, P., Fumagalli, G. G., Colombi, A., Giulietti, G., Serra, L., Triulzi, F., Bozzali, M., Scarpini, E. & Galimberti, D., Jan 1 2018, (Accepted/In press) In : Multiple Sclerosis Journal.

Research output: Contribution to journalArticle

Amyloid
Multiple Sclerosis
Cerebrospinal Fluid
Disease Progression
Biomarkers

CXCR4 involvement in neurodegenerative diseases

Bonham, L. W., Karch, C. M., Fan, C. C., Tan, C., Geier, E. G., Wang, Y., Wen, N., Broce, I. J., Li, Y., Barkovich, M. J., Ferrari, R., Hardy, J., Momeni, P., Höglinger, G., Müller, U., Hess, C. P., Sugrue, L. P., Dillon, W. P., Schellenberg, G. D., Miller, B. L. & 158 others, Andreassen, O. A., Dale, A. M., Barkovich, A. J., Yokoyama, J. S., Desikan, R. S., Hernandez, D. G., Nalls, M. A., Rohrer, J. D., Ramasamy, A., Kwok, J. B. J., Dobson-Stone, C., Schofield, P. R., Halliday, G. M., Hodges, J. R., Piguet, O., Bartley, L., Thompson, E., Haan, E., Hernández, I., Ruiz, A., Boada, M., Borroni, B., Padovani, A., Cruchaga, C., Cairns, N. J., Benussi, L., Binetti, G., Ghidoni, R., Forloni, G., Albani, D., Galimberti, D., Fenoglio, C., Serpente, M., Scarpini, E., Clarimón, J., Lleó, A., Blesa, R., Waldö, M. L., Nilsson, K., Nilsson, C., MacKenzie, I. R. A., Hsiung, G-YR., Mann, D. M. A., Grafman, J., Morris, C. M., Attems, J., Griffiths, T. D., McKeith, I. G., Thomas, A. J., Pietrini, P., Huey, E. D., Wassermann, E. M., Baborie, A., Jaros, E., Tierney, M. C., Pastor, P., Razquin, C., Ortega-Cubero, S., Alonso, E., Perneczky, R., Diehl-Schmid, J., Alexopoulos, P., Kurz, A., Rainero, I., Rubino, E., Pinessi, L., Rogaeva, E., George-Hyslop, P. S., Rossi, G., Tagliavini, F., Giaccone, G., Rowe, J. B., Schlachetzki, J. C. M., Uphill, J., Collinge, J., Mead, S., Danek, A., Van Deerlin, V. M., Grossman, M., Trojanowski, J. Q., Van Der Zee, J., Cruts, M., Van Broeckhoven, C., Cappa, S. F., Leber, I., Hannequin, D., Golfier, V., Vercelletto, M., Brice, A., Nacmias, B., Sorbi, S., Bagnoli, S., Piaceri, I., Nielsen, J. E., Hjermind, L. E., Riemenschneider, M., Mayhaus, M., Ibach, B., Gasparoni, G., Pichler, S., Gu, W., Rossor, M. N., Fox, N. C., Warren, J. D., Spillantini, M. G., Morris, H. R., Rizzu, P., Heutink, P., Snowden, J. S., Rollinson, S., Richardson, A., Gerhard, A., Bruni, A. C., Maletta, R., Frangipane, F., Cupidi, C., Bernardi, L., Anfossi, M., Gallo, M., Conidi, M. E., Smirne, N., Rademakers, R., Baker, M., Dickson, D. W., Graff-Radford, N. R., Petersen, R. C., Knopman, D., Josephs, K. A., Boeve, B. F., Parisi, J. E., Seeley, W. W., Karydas, A. M., Rosen, H., Van Swieten, J. C., Dopper, E. G. P., Seelaar, H., Pijnenburg, Y. A. L., Scheltens, P., Logroscino, G., Capozzo, R., Novelli, V., Puca, A. A., Franceschi, M., Postiglione, A., Milan, G., Sorrentino, P., Kristiansen, M., Chiang, H-H., Graff, C., Pasquier, F., Rollin, A., Deramecourt, V., Lebouvier, T., Kapogiannis, D., Ferrucci, L., Pickering-Brown, S., Singleton, A. B. & International FTD-Genomics Consortium (IFGC) International Parkinson's Disease Genetics Consortium (IPDGC), I. G. O. A. P. IGAP., 2018, In : Translational Psychiatry. 8, 1

Research output: Contribution to journalArticle

Progressive Supranuclear Palsy
Neurodegenerative Diseases
Parkinson Disease
Frontotemporal Dementia
Brain

Distinct patterns of brain atrophy in Genetic Frontotemporal Dementia Initiative (GENFI) cohort revealed by visual rating scales

Fumagalli, G. G., Basilico, P., Arighi, A., Bocchetta, M., Dick, K. M., Cash, D. M., Harding, S., Mercurio, M., Fenoglio, C., Pietroboni, A. M., Ghezzi, L., van Swieten, J., Borroni, B., de Mendonça, A., Masellis, M., Tartaglia, M. C., Rowe, J. B., Graff, C., Tagliavini, F., Frisoni, G. B. & 7 others, Laforce, R., Finger, E., Sorbi, S., Scarpini, E., Rohrer, J. D., Galimberti, D. & Genetic FTD Initiative (GENFI), May 24 2018, In : Alzheimer's Research and Therapy. 10, 1, p. 46

Research output: Contribution to journalArticle

Frontotemporal Dementia
Atrophy
Brain
Microtubule-Associated Proteins
Temporal Lobe
6 Citations (Scopus)

Distinct patterns of brain atrophy in Genetic Frontotemporal Dementia Initiative (GENFI) cohort revealed by visual rating scales

Fumagalli, G. G., Basilico, P., Arighi, A., Bocchetta, M., Dick, K. M., Cash, D. M., Harding, S., Mercurio, M., Fenoglio, C., Pietroboni, A. M., Ghezzi, L., Van Swieten, J., Borroni, B., De Mendonça, A., Masellis, M., Tartaglia, M. C., Rowe, J. B., Graff, C., Tagliavini, F., Frisoni, G. B. & 6 others, Laforce, R., Finger, E., Sorbi, S., Scarpini, E., Rohrer, J. D. & Galimberti, D., May 24 2018, In : Alzheimer's Research and Therapy. 10, 1, 46.

Research output: Contribution to journalArticle

Frontotemporal Dementia
Atrophy
Brain
Microtubule-Associated Proteins
Temporal Lobe
2 Citations (Scopus)

Epigenetic regulatory modifications in genetic and sporadic frontotemporal dementia

Fenoglio, C., Scarpini, E. & Galimberti, D., Jun 3 2018, In : Expert Review of Neurotherapeutics. 18, 6, p. 469-475 7 p.

Research output: Contribution to journalReview article

Frontotemporal Dementia
Epigenomics
Neurodegenerative Diseases
PubMed
Dementia

Frontotemporal dementia misdiagnosed for post-treatment lyme disease syndrome or vice versa? A treviso dementia (TREDEM) registry case report

Di Battista, M. E., Dell'Acqua, C., Baroni, L., Fenoglio, C., Galimberti, D. & Gallucci, M., Jan 1 2018, In : Journal of Alzheimer's Disease. 66, 2, p. 445-451 7 p.

Research output: Contribution to journalArticle

Frontotemporal Dementia
Lyme Disease
Diagnostic Errors
Dementia
Registries

Genetically elevated high-density lipoprotein cholesterol through the cholesteryl ester transfer protein gene does not associate with risk of Alzheimer's disease

International Genomics of Alzheimer's Project (IGAP), ARUK Consortium, GERAD/PERADES, CHARGE, ADGC, EADI, Peloso, G. M., van der Lee, S. J., Sims, R., van der Lee, S. J., Naj, A. C., Bellenguez, C., Badarinarayan, N., Jakobsdottir, J., Kunkle, B. W., Boland, A., Raybould, R., Bis, J. C., Martin, E. R., Grenier-Boley, B., Heilmann-Heimbach, S., Chouraki, V., Kuzma, A. B. & 33 others, Sleegers, K., Vronskaya, M., Ruiz, A., Graham, R. R., Olaso, R., Hoffmann, P., Grove, M. L., Vardarajan, B. N., Hiltunen, M., Nöthen, M. M., White, C. C., Hamilton-Nelson, K. L., Epelbaum, J., Maier, W., Choi, S. H., Seripa, D., Spalletta, G., Bossù, P., Hughes, J. T., Fenoglio, C., Serpente, M., Arcaro, M., Caltagirone, C., Orfei, M. D., Ciaramella, A., Sorbi, S., Pilotto, A., Bosco, P., Gallo, M., Galimberti, D., Scarpini, E., Mancuso, M. & Daniele, A., Jan 1 2018, In : Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring. 10, p. 595-598 4 p.

Research output: Contribution to journalArticle

Cholesterol Ester Transfer Proteins
HDL Cholesterol
Alzheimer Disease
Genes
Single Nucleotide Polymorphism

Genetics and epigenetics in the neurodegenerative disorders of the central nervous system

Fenoglio, C., Jan 1 2018, NeurodegeneratIve Diseases: Clinical Aspects, Molecular Genetics and Biomarkers. Springer International Publishing AG, p. 1-20 20 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Neurology
Epigenomics
Neurodegenerative Diseases
Frontotemporal Dementia
Alzheimer Disease
27 Citations (Scopus)

Immune-related genetic enrichment in frontotemporal dementia: An analysis of genome-wide association studies

International FTD-Genomics Consortium, Jan 1 2018, In : PLoS Medicine. 15, 1, e1002487.

Research output: Contribution to journalArticle

Frontotemporal Dementia
Genome-Wide Association Study
Immune System Diseases
HLA Antigens
Progressive Supranuclear Palsy
1 Citation (Scopus)

Microtubule defects in mesenchymal stromal cells distinguish patients with Progressive Supranuclear Palsy

Calogero, A. M., Viganò, M., Budelli, S., Galimberti, D., Fenoglio, C., Cartelli, D., Lazzari, L., Lehenkari, P., Canesi, M., Giordano, R., Cappelletti, G. & Pezzoli, G., May 1 2018, In : Journal of Cellular and Molecular Medicine. 22, 5, p. 2670-2679 10 p.

Research output: Contribution to journalArticle

Progressive Supranuclear Palsy
Mesenchymal Stromal Cells
Microtubules
Neurodegenerative Diseases
Tauopathies

Profiling of specific gene expression pathways in peripheral cells from prodromal Alzheimer's disease patients

Serpente, M., Fenoglio, C., Cioffi, S. M. G., Oldoni, E., Arcaro, M., Arighi, A., Fumagalli, G. G., Ghezzi, L., Scarpini, E. & Galimberti, D., Jan 1 2018, In : Journal of Alzheimer's Disease. 61, 4, p. 1289-1294 6 p.

Research output: Contribution to journalArticle

Gene Expression Profiling
Alzheimer Disease
Insulin Receptor
Biomarkers
Cerebrospinal Fluid
1 Citation (Scopus)

Progranulin as a therapeutic target for dementia

Galimberti, D., Fenoglio, C. & Scarpini, E., Jul 3 2018, In : Expert Opinion on Therapeutic Targets. 22, 7, p. 579-585 7 p.

Research output: Contribution to journalReview article

Frontotemporal Dementia
Dementia
Mutation
Tumors
Brain
9 Citations (Scopus)

Progranulin plasma levels predict the presence of GRN mutations in asymptomatic subjects and do not correlate with brain atrophy: Results from the GENFI study

Galimberti, D., Fumagalli, G. G., Fenoglio, C., Cioffi, S. M. G., Arighi, A., Serpente, M., Borroni, B., Padovani, A., Tagliavini, F., Masellis, M., Tartaglia, M. C., van Swieten, J., Meeter, L., Graff, C., de Mendonça, A., Bocchetta, M., Rohrer, J. D. & Scarpini, E., 2018, In : Neurobiology of Aging. 62, p. 245.e9-245.e12

Research output: Contribution to journalArticle

Atrophy
Mutation
Brain
Frontotemporal Dementia
Age of Onset
5 Citations (Scopus)
Brain-Derived Neurotrophic Factor
DNA Methylation
Bipolar Disorder
Genes
Epigenomics
6 Citations (Scopus)

Role of Genetics and Epigenetics in the Pathogenesis of Alzheimer's Disease and Frontotemporal Dementia

Fenoglio, C., Scarpini, E., Serpente, M. & Galimberti, D., Jan 1 2018, In : Journal of Alzheimer's Disease. 62, 3, p. 913-932 20 p.

Research output: Contribution to journalReview article

Frontotemporal Dementia
Epigenomics
Alzheimer Disease
Untranslated RNA
Chromatin Assembly and Disassembly
1 Citation (Scopus)

Word and Picture Version of the Free and Cued Selective Reminding Test (FCSRT): Is There Any Difference?

Arighi, A., Carandini, T., Mercurio, M., Carpani, G., Pietroboni, A. M., Fumagalli, G., Ghezzi, L., Basilico, P., Calvi, A., Scarioni, M., De Riz, M., Fenoglio, C., Scola, E., Triulzi, F., Galimberti, D. & Scarpini, E., 2018, In : Journal of Alzheimer's Disease. 61, 1, p. 47-52 6 p.

Research output: Contribution to journalArticle

Atrophy
Episodic Memory
Neuropsychological Tests
Magnetic Resonance Spectroscopy
Brain
2017
10 Citations (Scopus)

CSF β-amyloid and white matter damage: a new perspective on Alzheimer's disease

Pietroboni, A. M., Scarioni, M., Carandini, T., Basilico, P., Cadioli, M., Giulietti, G., Arighi, A., Caprioli, M., Serra, L., Sina, C., Fenoglio, C., Ghezzi, L., Fumagalli, G. G., De Riz, M. A., Calvi, A., Triulzi, F., Bozzali, M., Scarpini, E. & Galimberti, D., Oct 20 2017, In : Journal of Neurology, Neurosurgery and Psychiatry.

Research output: Contribution to journalArticle

Amyloid
Cerebrospinal Fluid
Alzheimer Disease
White Matter
Pathology
12 Citations (Scopus)

CSF β-amyloid as a putative biomarker of disease progression in multiple sclerosis

Pietroboni, A. M., Schiano Di Cola, F., Scarioni, M., Fenoglio, C., Spanò, B., Arighi, A., Cioffi, S. M. G., Oldoni, E., De Riz, M. A., Basilico, P., Calvi, A., Fumagalli, G. G., Triulzi, F., Galimberti, D., Bozzali, M. & Scarpini, E., Jul 1 2017, In : Multiple Sclerosis. 23, 8, p. 1085-1091 7 p.

Research output: Contribution to journalArticle

Amyloid
Multiple Sclerosis
Cerebrospinal Fluid
Disease Progression
Biomarkers
1 Citation (Scopus)

Effects of 1-month R-α-lipoic acid supplementation on humans oxidative status: A pilot study

Vigna, L., Solimena, G., Bamonti, F., Arcaro, M., Fenoglio, C., Oldoni, E., Dellanoce, C., Rossi, P., Gori, F., Figliola, R. & Cighetti, G., 2017, In : Progress in Nutrition. 19, 1, p. 14-25 12 p.

Research output: Contribution to journalArticle

lipoic acid
Thioctic Acid
Antioxidants
glutathione
antioxidants
6 Citations (Scopus)

Evidence of CNS β-amyloid deposition in Nasu-Hakola disease due to the TREM2 Q33X mutation

Ghezzi, L., Carandini, T., Arighi, A., Fenoglio, C., Arcaro, M., De Riz, M., Pietroboni, A. M., Fumagalli, G. G., Basilico, P., Calvi, A., Scarioni, M., Colombi, A., Serpente, M., Marotta, G., Benti, R., Scarpini, E. & Galimberti, D., Dec 12 2017, In : Neurology. 89, 24, p. 2503-2505 3 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)

Extracellular proteasome-osteopontin circuit regulates cell migration with implications in multiple sclerosis

Dianzani, C., Bellavista, E., Liepe, J., Verderio, C., Martucci, M., Santoro, A., Chiocchetti, A., Gigliotti, C. L., Boggio, E., Ferrara, B., Riganti, L., Keller, C., Janek, K., Niewienda, A., Fenoglio, C., Sorosina, M., Cantello, R., Kloetzel, P. M., Stumpf, M. P. H., Paul, F. & 6 others, Ruprecht, K., Galimberti, D., Martinelli Boneschi, F., Comi, C., Dianzani, U. & Mishto, M., Mar 9 2017, In : Scientific Reports. 7, 43718.

Research output: Contribution to journalArticle

Osteopontin
Proteasome Endopeptidase Complex
Multiple Sclerosis
Cell Movement
Extracellular Space
13 Citations (Scopus)

Extracellular proteasome-osteopontin circuit regulates cell migration with implications in multiple sclerosis

Dianzani, C., Bellavista, E., Liepe, J., Verderio, C., Martucci, M., Santoro, A., Chiocchetti, A., Gigliotti, CL., Boggio, E., Ferrara, B., Riganti, L., Keller, C., Janek, K., Niewienda, A., Fenoglio, C., Sorosina, M., Cantello, R., Kloetzel, PM., Stumpf, MPH., Paul, F. & 6 others, Ruprecht, K., Galimberti, D., Martinelli-Boneschi, F., Comi, C., Dianzani, U. & Mishto, M., 2017, In : Scientific Reports. 7, 6, 43718.

Research output: Contribution to journalArticle

Osteopontin
Proteasome Endopeptidase Complex
Multiple Sclerosis
Cell Movement
Extracellular Space
13 Citations (Scopus)

Extracellular proteasome-osteopontin circuit regulates cell migration with implications in multiple sclerosis

Dianzani, C., Bellavista, E., Liepe, J., Verderio, C., Martucci, M., Santoro, A., Chiocchetti, A., Gigliotti, C. L., Boggio, E., Ferrara, B., Riganti, L., Keller, C., Janek, K., Niewienda, A., Fenoglio, C., Sorosina, M., Cantello, R., Kloetzel, P. M., Stumpf, M. P. H., Paul, F. & 6 others, Ruprecht, K., Galimberti, D., Boneschi, F. M., Comi, C., Dianzani, U. & Mishto, M., Mar 9 2017, In : Scientific Reports. 7, 43718.

Research output: Contribution to journalArticle

Osteopontin
Proteasome Endopeptidase Complex
Multiple Sclerosis
Cell Movement
Extracellular Space
4 Citations (Scopus)

Improved Cerebrospinal Fluid-Based Discrimination between Alzheimer's Disease Patients and Controls after Correction for Ventricular Volumes

Van Waalwijk Van Doorn, L. J. C., Gispert, J. D., Kuiperij, H. B., Claassen, J. A. H. R., Arighi, A., Baldeiras, I., Blennow, K., Bozzali, M., Castelo-Branco, M., Cavedo, E., Emek-Savaş, D. D., Eren, E., Eusebi, P., Farotti, L., Fenoglio, C., Ormaechea, J. F., Freund-Levi, Y., Frisoni, G. B., Galimberti, D., Genc, S. & 31 others, Greco, V., Hampel, H., Herukka, S. K., Liu, Y., Lladó, A., Lleó, A., Nobili, F. M., Oguz, K. K., Parnetti, L., Pereira, J., Picco, A., Pikkarainen, M., De Oliveira, C. R., Saka, E., Salvadori, N., Sanchez-Valle, R., Santana, I., Scarpini, E., Scheltens, P., Soininen, H., Tarducci, R., Teunissen, C., Tsolaki, M., Urbani, A., Vilaplana, E., Visser, P. J., Wallin, A. K., Yener, G., Molinuevo, J. L., Meulenbroek, O. & Verbeek, M. M., 2017, In : Journal of Alzheimer's Disease. 56, 2, p. 543-555 13 p.

Research output: Contribution to journalArticle

Cerebrospinal Fluid
Alzheimer Disease
Biomarkers
Area Under Curve
Magnetic Resonance Imaging

Natural vegan meal replacement: Metabolic and oxidative modulation on overweight subjects

Vigna, L., Galimberti, D., De Giuseppe, R., Cossovich, A., Sommaruga, D., De Liso, F., Gori, F., Ingenito, M. R., Napolitano, F., Tomaino, L., Novembrino, C., Fenoglio, C. & Bamonti, F., 2017, In : Progress in Nutrition. 19, 2, p. 127-137 11 p.

Research output: Contribution to journalArticle

Meals
obesity
triacylglycerols
oxen
metabolism
4 Citations (Scopus)

Rapidly progressive primary progressive aphasia and parkinsonism with novel GRN mutation

Galimberti, D., Cioffi, S. M. G., Fenoglio, C., Serpente, M., Oblak, A. L., Rodriguez-Porcel, F., Oldoni, E., Hagen, M. C., Arcaro, M., Scarpini, E., Ghetti, B. & Espay, A. J., 2017, In : Movement Disorders. 32, 3, p. 476-478

Research output: Contribution to journalArticle

187 Citations (Scopus)

Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease

Sims, R., van der Lee, S. J., Naj, A. C., Bellenguez, C., Badarinarayan, N., Jakobsdottir, J., Kunkle, B. W., Boland, A., Raybould, R., Bis, J. C., Martin, E. R., Grenier-Boley, B., Heilmann-Heimbach, S., Chouraki, V., Kuzma, A. B., Sleegers, K., Vronskaya, M., Ruiz, A., Graham, R. R., Olaso, R. & 433 others, Hoffmann, P., Grove, M. L., Vardarajan, B. N., Hiltunen, M., Noethen, M. M., White, C. C., Hamilton-Nelson, K. L., Epelbaum, J., Maier, W., Choi, S-H., Beecham, G. W., Dulary, C., Herms, S., Smith, A. V., Funk, C. C., Derbois, C., Forstner, A. J., Ahmad, S., Li, H., Bacq, D., Harold, D., Satizabal, C. L., Valladares, O., Squassina, A., Thomas, R., Brody, J. A., Qu, L., Sanchez-Juan, P., Morgan, T., Wolters, F. J., Zhao, Y., Sanchez Garcia, F., Denning, N., Fornage, M., Malamon, J., Deniz Naranjo, M. C., Majounie, E., Mosley, T. H., Dombroski, B., Wallon, D., Lupton, M. K., Dupuis, J., Whitehead, P., Fratiglioni, L., Medway, C., Jian, X., Mukherjee, S., Keller, L., Brown, K., Lin, H., Cantwell, L. B., Panza, F., McGuinness, B., Moreno-Grau, S., Burgess, J. D., Solfrizzi, V., Proitsi, P., Adams, H. H., Allen, M., Seripa, D., Pastor, P., Cupples, L. A., Price, N. D., Hannequin, D., Frank-Garcia, A., Levy, D., Chakrabarty, P., Caffarra, P., Giegling, I., Beiser, A. S., Giedraitis, V., Hampel, H., Garcia, M. E., Wang, X., Lannfelt, L., Mecocci, P., Eiriksdottir, G., Crane, P. K., Pasquier, F., Boccardi, V., Henandez, I., Barber, R. C., Scherer, M., Tarraga, L., Adams, P. M., Leber, M., Chen, Y., Albert, M. S., Riedel-Heller, S., Emilsson, V., Beekly, D., Braae, A., Schmidt, R., Blacker, D., Masullo, C., Schmidt, H., Doody, R. S., Spalletta, G., Longstreth, Jr., W. T., Fairchild, T. J., Bossu, P., Lopez, O. L., Frosch, M. P., Sacchinelli, E., Ghetti, B., Yang, Q., Huebinger, R. M., Jessen, F., Li, S., Kamboh, M. I., Morris, J. C., Sotolongo-Grau, O., Katz, M. J., Corcoran, C., Dunstan, M., Braddel, A., Thomas, C., Meggy, A., Marshall, R., Gerrish, A., Chapman, J., Aguilar, M., Taylor, S., Hill, M., Diez Fairen, M., Hodges, A., Vellas, B., Soininen, H., Kloszewska, I., Daniilidou, M., Uphill, J., Patel, Y., Hughes, J. T., Lord, J., Turton, J., Hartmann, A. M., Cecchetti, R., Fenoglio, C., Serpente, M., Arcaro, M., Caltagirone, C., Orfei, M. D., Ciaramella, A., Pichler, S., Mayhaus, M., Gu, W., Lleo, A., Forte, J., Blesa, R., Barber, I. S., Brookes, K., Cupidi, C., Maletta, R. G., Carrell, D., Sorbi, S., Moebus, S., Urbano, M., Pilotto, A., Kornhuber, J., Bosco, P., Todd, S., Craig, D., Johnston, J., Gill, M., Lawlor, B., Lynch, A., Fox, N. C., Hardy, J., Albin, R. L., Apostolova, L. G., Arnold, S. E., Asthana, S., Atwood, C. S., Baldwin, C. T., Barnes, L. L., Barral, S., Beach, T. G., Becker, J. T., Bigio, E. H., Bird, T. D., Boeve, B. F., Bowen, J. D., Boxer, A., Burke, J. R., Burns, J. M., Buxbaum, J. D., Cairns, N. J., Cao, C., Carlson, C. S., Carlsson, C. M., Carney, R. M., Carrasquillo, M. M., Carroll, S. L., Diaz, C. C., Chui, H. C., Clark, D. G., Cribbs, D. H., Crocco, E. A., DeCarli, C., Dick, M., Duara, R., Evans, D. A., Faber, K. M., Fallon, K. B., Fardo, D. W., Farlow, M. R., Ferris, S., Foroud, T. M., Galasko, D. R., Gearing, M., Geschwind, D. H., Gilbert, J. R., Graff-Radford, N. R., Green, R. C., Growdon, J. H., Hamilton, R. L., Harrell, L. E., Honig, L. S., Huentelman, M. J., Hulette, C. M., Hyman, B. T., Jarvik, G. P., Abner, E., Jin, L-W., Jun, G., Karydas, A., Kaye, J. A., Kim, R., Kowall, N. W., Kramer, J. H., LaFerla, F. M., Lah, J. J., Leverenz, J. B., Levey, A. I., Li, G., Lieberman, A. P., Lunetta, K. L., Lyketsos, C. G., Marson, D. C., Martiniuk, F., Mash, D. C., Masliah, E., McCormick, W. C., McCurry, S. M., McDavid, A. N., Mckee, A. C., Mesulam, M., Miller, B. L., Miller, C. A., Miller, J. W., Morris, J. C., Murrell, J. R., Myers, A. J., O'Bryant, S., Pankratz, V. S., Pankratz, V. S., Parisi, J. E., Paulson, H. L., Perry, W., Peskind, E., Pierce, A., Poon, W. W., Potter, H., Quinn, J. F., Raj, A., Raskind, M., Reisberg, B., Reitz, C., Ringman, J. M., Roberson, E. D., Rogaeva, E., Rosen, H. J., Rosenberg, R. N., Sager, M. A., Saykin, A. J., Schneider, J. A., Schneider, L. S., Seeley, W. W., Smith, A. G., Sonnen, J. A., Spina, S., Stern, R. A., Swerdlow, R. H., Tanzi, R. E., Thornton-Wells, T. A., Trojanowski, J. Q., Troncoso, J. C., Van Deerlin, V. M., Van Eldik, L. J., Vinters, H. V., Vonsattel, J. P., Weintraub, S., Welsh-Bohmer, K. A., Wilhelmsen, K. C., Williamson, J., Woltjer, R. L., Wright, C. B., Yu, C-E., Yu, L., Garzia, F., Golamaully, F., Septier, G., Engelborghs, S., Vandenberghe, R., De Deyn, P. P., Munoz Fernadez, C., Aladro Benito, Y., Thonberg, H., Forsell, C., Lilius, L., Kinhult-Stahlbom, A., Kilander, L., Brundin, R., Concari, L., Helisalmi, S., Koivisto, A. M., Haapasalo, A., Dermecourt, V., Fievet, N., Hanon, O., Dufouil, C., Brice, A., Ritchie, K., Dubois, B., Himali, J. J., Keene, C. D., Tschanz, J., Fitzpatrick, A. L., Kukull, W. A., Norton, M., Aspelund, T., Larson, E. B., Munger, R., Rotter, J. I., Lipton, R. B., Bullido, M. J., Hofman, A., Montine, T. J., Coto, E., Boerwinkle, E., Petersen, R. C., Alvarez, V., Rivadeneira, F., Reiman, E. M., Gallo, M., O'Donnell, C. J., Reisch, J. S., Bruni, A. C., Royall, D. R., Dichgans, M., Sano, M., Galimberti, D., St George-Hyslop, P., Scarpini, E., Tsuang, D. W., Mancuso, M., Bonuccelli, U., Winslow, A. R., Daniele, A., Wu, C-K., Peters, O., Nacmias, B., Riemenschneider, M., Heun, R., Brayne, C., Rubinsztein, D. C., Bras, J., Guerreiro, R., Al-Chalabi, A., Shaw, C. E., Collinge, J., Mann, D., Tsolaki, M., Clarimon, J., Sussams, R., Lovestone, S., O'Donovan, M. C., Owen, M. J., Behrens, T. W., Mead, S., Goate, A. M., Uitterlinden, A. G., Holmes, C., Cruchaga, C., Ingelsson, M., Bennett, D. A., Powell, J., Golde, T. E., Graff, C., De Jager, P. L., Morgan, K., Ertekin-Taner, N., Combarros, O., Psaty, B. M., Passmore, P., Younkin, S. G., Berr, C., Gudnason, V., Rujescu, D., Dickson, D. W., Dartigues, J-F., DeStefano, A. L., Ortega-Cubero, S., Hakonarson, H., Campion, D., Boada, M., Kauwe, J. K., Farrer, L. A., Van Broeckhoven, C., Ikram, M. A., Jones, L., Haines, J. L., Tzourio, C., Launer, L. J., Escott-Price, V., Mayeux-, R., Deleuze, J-F., Amin, N., Holmans, P. A., Pericak-Vance, M. A., Amouyel, P., van Duijn, C. M., Ramirez, A., Wang, L-S., Lambert, J-C., Seshadri, S., Williams, J., Schellenberg, G. D., [Unknown], ARUKC., PERADES, GERAD., [Unknown], CHARGE., [Unknown], ADGC. & [Unknown], EADI., Sep 1 2017, In : Nature Genetics. 49, 9, p. 1373+

Research output: Contribution to journalArticle

187 Citations (Scopus)

Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease

Sims, R., van der Lee, S. J., Naj, A. C., Bellenguez, C., Badarinarayan, N., Jakobsdottir, J., Kunkle, B. W., Boland, A., Raybould, R., Bis, J. C., Martin, E. R., Grenier-Boley, B., Heilmann-Heimbach, S., Chouraki, V., Kuzma, A. B., Sleegers, K., Vronskaya, M., Ruiz, A., Graham, R. R., Olaso, R. & 31 others, Hoffmann, P., Grove, M. L., Vardarajan, B. N., Hiltunen, M., Nöthen, M. M., White, C. C., Hamilton-Nelson, K. L., Epelbaum, J., Maier, W., Choi, S-H., Beecham, G. W., Dulary, C., Herms, S., Smith, A. V., Funk, C. C., Derbois, C., Seripa, D., Spalletta, G., Bossù, P., Fenoglio, C., Serpente, M., Arcaro, M., Caltagirone, C., Orfei, M. D., Ciaramella, A., Sorbi, S., Bosco, P., Galimberti, D., Scarpini, E., Daniele, A. & ARUK Consortium, Sep 2017, In : Nature Genetics. 49, 9, p. 1373-1384 12 p.

Research output: Contribution to journalArticle

Innate Immunity
Alzheimer Disease
Odds Ratio
Microglia
Genotype
187 Citations (Scopus)

Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease

Sims, R., Van Der Lee, S. J., Naj, A. C., Bellenguez, C., Badarinarayan, N., Jakobsdottir, J., Kunkle, B. W., Boland, A., Raybould, R., Bis, J. C., Martin, E. R., Grenier-Boley, B., Heilmann-Heimbach, S., Chouraki, V., Kuzma, A. B., Sleegers, K., Vronskaya, M., Ruiz, A., Graham, R. R., Olaso, R. & 429 others, Hoffmann, P., Grove, M. L., Vardarajan, B. N., Hiltunen, M., Nöthen, M. M., White, C. C., Hamilton-Nelson, K. L., Epelbaum, J., Maier, W., Choi, S-H., Beecham, G. W., Dulary, C., Herms, S., Smith, A. V., Funk, C. C., Derbois, C., Forstner, A. J., Ahmad, S., Li, H., Bacq, D., Harold, D., Satizabal, C. L., Valladares, O., Squassina, A., Thomas, R., Brody, J. A., Qu, L., Sánchez-Juan, P., Morgan, T., Wolters, F. J., Zhao, Y., Garcia, F. S., Denning, N., Fornage, M., Malamon, J., Naranjo, M. C. D., Majounie, E., Mosley, T. H., Dombroski, B., Wallon, D., Lupton, M. K., Dupuis, J., Whitehead, P., Fratiglioni, L., Medway, C., Jian, X., Mukherjee, S., Keller, L., Brown, K., Lin, H., Cantwell, L. B., Panza, F., McGuinness, B., Moreno-Grau, S., Burgess, J. D., Solfrizzi, V., Proitsi, P., Adams, H. H., Allen, M., Seripa, D., Pastor, P., Cupples, L. A., Price, N. D., Hannequin, D., Frank-García, A., Levy, D., Chakrabarty, P., Caffarra, P., Giegling, I., Beiser, A. S., Giedraitis, V., Hampel, H., Garcia, M. E., Wang, X., Lannfelt, L., Mecocci, P., Eiriksdottir, G., Crane, P. K., Pasquier, F., Boccardi, V., Henández, I., Barber, R. C., Scherer, M., Tarraga, L., Adams, P. M., Leber, M., Chen, Y., Albert, M. S., Riedel-Heller, S., Emilsson, V., Beekly, D., Braae, A., Schmidt, R., Blacker, D., Masullo, C., Schmidt, H., Doody, R. S., Spalletta, G., Jr, W. T. L., Fairchild, T. J., Bossù, P., Lopez, O. L., Frosch, M. P., Sacchinelli, E., Ghetti, B., Yang, Q., Huebinger, R. M., Jessen, F., Li, S., Kamboh, M. I., Morris, J., Sotolongo-Grau, O., Katz, M. J., Corcoran, C., Dunstan, M., Braddel, A., Thomas, C., Meggy, A., Marshall, R., Gerrish, A., Chapman, J., Aguilar, M., Taylor, S., Hill, M., Fairén, M. D., Hodges, A., Vellas, B., Soininen, H., Kloszewska, I., Daniilidou, M., Uphill, J., Patel, Y., Hughes, J. T., Lord, J., Turton, J., Hartmann, A. M., Cecchetti, R., Fenoglio, C., Serpente, M., Arcaro, M., Caltagirone, C., Orfei, M. D., Ciaramella, A., Pichler, S., Mayhaus, M., Gu, W., Lleó, A., Fortea, J., Blesa, R., Barber, I. S., Brookes, K., Cupidi, C., Maletta, R. G., Carrell, D., Sorbi, S., Moebus, S., Urbano, M., Pilotto, A., Kornhuber, J., Bosco, P., Todd, S., Craig, D., Johnston, J., Gill, M., Lawlor, B., Lynch, A., Fox, N. C., Hardy, J., Albin, R. L., Apostolova, L. G., Arnold, S. E., Asthana, S., Atwood, C. S., Baldwin, C. T., Barnes, L. L., Barral, S., Beach, T. G., Becker, J. T., Bigio, E. H., Bird, T. D., Boeve, B. F., Bowen, J. D., Boxer, A., Burke, J. R., Burns, J. M., Buxbaum, J. D., Cairns, N. J., Cao, C., Carlson, C. S., Carlsson, C. M., Carney, R. M., Carrasquillo, M. M., Carroll, S. L., Diaz, C. C., Chui, H. C., Clark, D. G., Cribbs, D. H., Crocco, E. A., Decarli, C., Dick, M., Duara, R., Evans, D. A., Faber, K. M., Fallon, K. B., Fardo, D. W., Farlow, M. R., Ferris, S., Foroud, T. M., Galasko, D. R., Gearing, M., Geschwind, D. H., Gilbert, J. R., Graff-Radford, N. R., Green, R. C., Growdon, J. H., Hamilton, R. L., Harrell, L. E., Honig, L. S., Huentelman, M. J., Hulette, C. M., Hyman, B. T., Jarvik, G. P., Abner, E., Jin, L-W., Jun, G., Karydas, A., Kaye, J. A., Kim, R., Kowall, N. W., Kramer, J. H., Laferla, F. M., Lah, J. J., Leverenz, J. B., Levey, A. I., Li, G., Lieberman, A. P., Lunetta, K. L., Lyketsos, C. G., Marson, D. C., Martiniuk, F., Mash, D. C., Masliah, E., McCormick, W. C., McCurry, S. M., McDavid, A. N., McKee, A. C., Mesulam, M., Miller, B. L., Miller, C. A., Miller, J. W., Morris, J. C., Murrell, J. R., Myers, A. J., O'Bryant, S., Olichney, J. M., Pankratz, V. S., Parisi, J. E., Paulson, H. L., Perry, W., Peskind, E., Pierce, A., Poon, W. W., Potter, H., Quinn, J. F., Raj, A., Raskind, M., Reisberg, B., Reitz, C., Ringman, J. M., Roberson, E. D., Rogaeva, E., Rosen, H. J., Rosenberg, R. N., Sager, M. A., Saykin, A. J., Schneider, J. A., Schneider, L. S., Seeley, W. W., Smith, A. G., Sonnen, J. A., Spina, S., Stern, R. A., Swerdlow, R. H., Tanzi, R. E., Thornton-Wells, T. A., Trojanowski, J. Q., Troncoso, J. C., Van Deerlin, V. M., Van Eldik, L. J., Vinters, H. V., Vonsattel, J. P., Weintraub, S., Welsh-Bohmer, K. A., Wilhelmsen, K. C., Williamson, J., Wingo, T. S., Woltjer, R. L., Wright, C. B., Yu, C-E., Yu, L., Garzia, F., Golamaully, F., Septier, G., Engelborghs, S., Vandenberghe, R., De Deyn, P. P., Fernadez, C. M., Benito, Y. A., Thonberg, H., Forsell, C., Lilius, L., Kinhult-Stählbom, A., Kilander, L., Brundin, R., Concari, L., Helisalmi, S., Koivisto, A. M., Haapasalo, A., Dermecourt, V., Fievet, N., Hanon, O., Dufouil, C., Brice, A., Ritchie, K., Dubois, B., Himali, J. J., Keene, C. D., Tschanz, J., Fitzpatrick, A. L., Kukull, W. A., Norton, M., Aspelund, T., Larson, E. B., Munger, R., Rotter, J. I., Lipton, R. B., Bullido, M. J., Hofman, A., Montine, T. J., Coto, E., Boerwinkle, E., Petersen, R. C., Alvarez, V., Rivadeneira, F., Reiman, E. M., Gallo, M., O'Donnell, C. J., Reisch, J. S., Bruni, A. C., Royall, D. R., Dichgans, M., Sano, M., Galimberti, D., St George-Hyslop, P., Scarpini, E., Tsuang, D. W., Mancuso, M., Bonuccelli, U., Winslow, A. R., Daniele, A., Wu, C-K., Peters, O., Nacmias, B., Riemenschneider, M., Heun, R., Brayne, C., Rubinsztein, D. C., Bras, J., Guerreiro, R., Al-Chalabi, A., Shaw, C. E., Collinge, J., Mann, D., Tsolaki, M., Clarimón, J., Sussams, R., Lovestone, S., O'Donovan, M. C., Owen, M. J., Behrens, T. W., Mead, S., Goate, A. M., Uitterlinden, A. G., Holmes, C., Cruchaga, C., Ingelsson, M., Bennett, D. A., Powell, J., Golde, T. E., Graff, C., De Jager, P. L., Morgan, K., Ertekin-Taner, N., Combarros, O., Psaty, B. M., Passmore, P., Younkin, S. G., Berr, C., Gudnason, V., Rujescu, D., Dickson, D. W., Dartigues, J-F., Destefano, A. L., Ortega-Cubero, S., Hakonarson, H., Campion, D., Boada, M., Kauwe, J. K., Farrer, L. A., Van Broeckhoven, C., Ikram, M. A., Jones, L., Haines, J. L., Tzourio, C., Launer, L. J., Escott-Price, V., Mayeux, R., Deleuze, J-F., Amin, N., Holmans, P. A., Pericak-Vance, M. A., Amouyel, P., Van Duijn, C. M., Ramirez, A., Wang, L-S., Lambert, J-C., Seshadri, S., Williams, J. & Schellenberg, G. D., 2017, In : Nature Genetics. 49, 9, p. 1373-1384 12 p.

Research output: Contribution to journalArticle

187 Citations (Scopus)

Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease

Sims, R., Van Der Lee, S. J., Naj, A. C., Bellenguez, C., Badarinarayan, N., Jakobsdottir, J., Kunkle, B. W., Boland, A., Raybould, R., Bis, J. C., Martin, E. R., Grenier-Boley, B., Heilmann-Heimbach, S., Chouraki, V., Kuzma, A. B., Sleegers, K., Vronskaya, M., Ruiz, A., Graham, R. R., Olaso, R. & 429 others, Hoffmann, P., Grove, M. L., Vardarajan, B. N., Hiltunen, M., Nöthen, M. M., White, C. C., Hamilton-Nelson, K. L., Epelbaum, J., Maier, W., Choi, S. H., Beecham, G. W., Dulary, C., Herms, S., Smith, A. V., Funk, C. C., Derbois, C., Forstner, A. J., Ahmad, S., Li, H., Bacq, D., Harold, D., Satizabal, C. L., Valladares, O., Squassina, A., Thomas, R., Brody, J. A., Qu, L., Sánchez-Juan, P., Morgan, T., Wolters, F. J., Zhao, Y., Garcia, F. S., Denning, N., Fornage, M., Malamon, J., Naranjo, M. C. D., Majounie, E., Mosley, T. H., Dombroski, B., Wallon, D., Lupton, M. K., Dupuis, J., Whitehead, P., Fratiglioni, L., Medway, C., Jian, X., Mukherjee, S., Keller, L., Brown, K., Lin, H., Cantwell, L. B., Panza, F., McGuinness, B., Moreno-Grau, S., Burgess, J. D., Solfrizzi, V., Proitsi, P., Adams, H. H., Allen, M., Seripa, D., Pastor, P., Cupples, L. A., Price, N. D., Hannequin, D., Frank-García, A., Levy, D., Chakrabarty, P., Caffarra, P., Giegling, I., Beiser, A. S., Giedraitis, V., Hampel, H., Garcia, M. E., Wang, X., Lannfelt, L., Mecocci, P., Eiriksdottir, G., Crane, P. K., Pasquier, F., Boccardi, V., Henández, I., Barber, R. C., Scherer, M., Tarraga, L., Adams, P. M., Leber, M., Chen, Y., Albert, M. S., Riedel-Heller, S., Emilsson, V., Beekly, D., Braae, A., Schmidt, R., Blacker, D., Masullo, C., Schmidt, H., Doody, R. S., Spalletta, G., Jr, W. T. L., Fairchild, T. J., Bossù, P., Lopez, O. L., Frosch, M. P., Sacchinelli, E., Ghetti, B., Yang, Q., Huebinger, R. M., Jessen, F., Li, S., Kamboh, M. I., Morris, J., Sotolongo-Grau, O., Katz, M. 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A., Powell, J., Golde, T. E., Graff, C., De Jager, P. L., Morgan, K., Ertekin-Taner, N., Combarros, O., Psaty, B. M., Passmore, P., Younkin, S. G., Berr, C., Gudnason, V., Rujescu, D., Dickson, D. W., Dartigues, J. F., Destefano, A. L., Ortega-Cubero, S., Hakonarson, H., Campion, D., Boada, M., Kauwe, J. K., Farrer, L. A., Van Broeckhoven, C., Ikram, M. A., Jones, L., Haines, J. L., Tzourio, C., Launer, L. J., Escott-Price, V., Mayeux, R., Deleuze, J. F., Amin, N., Holmans, P. A., Pericak-Vance, M. A., Amouyel, P., Van Duijn, C. M., Ramirez, A., Wang, L. S., Lambert, J. C., Seshadri, S., Williams, J. & Schellenberg, G. D., Sep 1 2017, In : Nature Genetics. 49, 9, p. 1373-1384 12 p.

Research output: Contribution to journalArticle

Innate Immunity
Gene Frequency
Alzheimer Disease
Odds Ratio
Microglia
19 Citations (Scopus)

Recognition of viral and self-antigens by TH1 and TH1/TH17 central memory cells in patients with multiple sclerosis reveals distinct roles in immune surveillance and relapses

Paroni, M., Maltese, V., De Simone, M., Ranzani, V., Larghi, P., Fenoglio, C., Pietroboni, A. M., De Riz, M. A., Crosti, M. C., Maglie, S., Moro, M., Caprioli, F., Rossi, R., Rossetti, G., Galimberti, D., Pagani, M., Scarpini, E., Abrignani, S. & Geginat, J., Sep 1 2017, In : Journal of Allergy and Clinical Immunology. 140, 3, p. 797-808 12 p.

Research output: Contribution to journalArticle

Viral Antigens
Autoantigens
Multiple Sclerosis
Recurrence
T-Lymphocytes
5 Citations (Scopus)
Brain-Derived Neurotrophic Factor
DNA Methylation
Bipolar Disorder
Genes
Epigenomics
2016
91 Citations (Scopus)

Cerebrospinal fluid soluble TREM2 is higher in Alzheimer disease and associated with mutation status

Piccio, L., Deming, Y., Del-Águila, J. L., Ghezzi, L., Holtzman, D. M., Fagan, A. M., Fenoglio, C., Galimberti, D., Borroni, B. & Cruchaga, C., 2016, In : Acta Neuropathologica. p. 925-933 9 p.

Research output: Contribution to journalArticle

Cerebrospinal Fluid
Alzheimer Disease
Mutation
Single Nucleotide Polymorphism
Cerebrospinal Fluid Proteins
5 Citations (Scopus)

CHRNA7 Gene and Response to Cholinesterase Inhibitors in an Italian Cohort of Alzheimer's Disease Patients

Clarelli, F., Mascia, E., Santangelo, R., Mazzeo, S., Giacalone, G., Galimberti, D., Fusco, F., Zuffi, M., Fenoglio, C., Franceschi, M., Scarpini, E., Forloni, G., Magnani, G., Comi, G., Albani, D. & Martinelli Boneschi, F., 2016, In : Journal of Alzheimer's Disease. 52, 4, p. 1203-1208 6 p.

Research output: Contribution to journalArticle

Cholinesterase Inhibitors
Alzheimer Disease
Cholinergic Receptors
Genes
Single Nucleotide Polymorphism

CHRNA7 Gene and Response to Cholinesterase Inhibitors in an Italian Cohort of Alzheimer's Disease Patients

Clarelli, F., Mascia, E., Santangelo, R., Mazzeo, S., Giacalone, G., Galimberti, D., Fusco, F., Zuffi, M., Fenoglio, C., Franceschi, M., Scarpini, E. A., Forloni, G., Magnani, G., Comi, G., Albani, D. & Martinelli Boneschi, F., 2016, In : Journal of Alzheimer's Disease. 52, 4, p. 1203-1208 6 p.

Research output: Contribution to journalArticle

Cholinesterase Inhibitors
Alzheimer Disease
Cholinergic Receptors
Genes
Single Nucleotide Polymorphism

CHRNA7 Gene and Response to Cholinesterase Inhibitors in an Italian Cohort of Alzheimer's Disease Patients

Clarelli, F., Mascia, E., Santangelo, R., Mazzeo, S., Giacalone, G., Galimberti, D., Fusco, F., Zuffi, M., Fenoglio, C., Franceschi, M., Scarpini, E. A., Forloni, G., Magnani, G., Comi, G., Albani, D. & Martinelli Boneschi, F., 2016, In : Journal of Alzheimer's Disease. 52, 4, p. 1203-1208 6 p.

Research output: Contribution to journalArticle

Cholinesterase Inhibitors
Alzheimer Disease
Cholinergic Receptors
Genes
Single Nucleotide Polymorphism