• 1390 Citations
  • 19 h-Index
20052016
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Research Output 2005 2016

  • 1390 Citations
  • 19 h-Index
  • 49 Article
2016

Prognostic Role of PD-L1 Expression in Renal Cell Carcinoma. A Systematic Review and Meta-Analysis

Iacovelli, R., Nolè, F., Verri, E., Renne, G., Paglino, C., Santoni, M., Cossu Rocca, M., Giglione, P., Aurilio, G., Cullurà, D., Cascinu, S. & Porta, C., Apr 2016, In : Targeted Oncology. 11, 2, p. 143-8 6 p.

Research output: Contribution to journalArticle

Renal Cell Carcinoma
Meta-Analysis
Neoplasms
PubMed
MEDLINE
9 Citations (Scopus)

Targeted therapy for renal cell carcinoma: focus on 2nd and 3rd line

Porta, C., Giglione, P. & Paglino, C., Jan 7 2016, (Accepted/In press) In : Expert Opinion on Pharmacotherapy. p. 1-13 13 p.

Research output: Contribution to journalArticle

Vascular Endothelial Growth Factor Receptor
Renal Cell Carcinoma
Protein-Tyrosine Kinases
Vascular Endothelial Growth Factor A
Expert Testimony
2015
1 Citation (Scopus)

Approccio al trattamento di prima linea del carcinoma renale a cellule chiare metastatico

Translated title of the contribution: Current approaches to the first-line treatment of clear-cell renal cell carcinomaGiglione, P., Lombardo, F., Toscani, I., Paglino, C. & Porta, C., Aug 1 2015, In : Recenti Progressi in Medicina. 106, 8, p. 370-379 10 p.

Research output: Contribution to journalArticle

Renal Cell Carcinoma
Therapeutics
Rare Diseases
Interferons
Disease-Free Survival
4 Citations (Scopus)

Comparing comparators: A look at control arms in kidney cancer studies over the years

Bracarda, S., Porta, C., Sisani, M., Marrocolo, F., Paglino, C., Hamzaj, A., Buono, S. D. & Sternberg, C. N., Jan 6 2015, In : British Journal of Cancer. 112, 1, p. 14-19 6 p.

Research output: Contribution to journalArticle

Kidney Neoplasms
Renal Cell Carcinoma
Randomized Controlled Trials
Pharmaceutical Preparations
Therapeutics

Diffusion of biosimilar hemopoietic growth factors use in oncology practice: an Italian experience

Perfetti, V., Dalle Carbonare, S., Vecchio, S., Paglino, C., Secondino, S., Tringali, M., Pedrazzoli, P. & Dellagiovanna, M., Dec 25 2015, In : PharmacoEconomics - Italian Research Articles. 17, 1, 3.

Research output: Contribution to journalArticle

Biosimilar Pharmaceuticals
Intercellular Signaling Peptides and Proteins
Pharmacovigilance
Pharmaceutical Preparations
Italy
29 Citations (Scopus)

Dovitinib (CHIR258, TKI258): Structure, development and preclinical and clinical activity

Porta, C., Giglione, P., Liguigli, W. & Paglino, C., Jan 1 2015, In : Future Oncology. 11, 1, p. 39-50 12 p.

Research output: Contribution to journalArticle

Fibroblast Growth Factor Receptors
Vascular Endothelial Growth Factor Receptor
Platelet-Derived Growth Factor Receptors
Renal Cell Carcinoma
Protein-Tyrosine Kinases
12 Citations (Scopus)
Papillomavirus Infections
Paraffin
Formaldehyde
In Situ Hybridization
Carcinoma
12 Citations (Scopus)
Tonsillar Neoplasms
Oropharyngeal Neoplasms
Intercellular Junctions
Guanine Deaminase
Carcinoma
20 Citations (Scopus)

Osteonecrosis of the Jaw in Patients with Metastatic Renal Cell Cancer Treated with Bisphosphonates and Targeted Agents: Results of an Italian Multicenter Study and Review of the Literature

Fusco, V., Porta, C., Saia, G., Paglino, C., Bettini, G., Scoletta, M., Bonacina, R., Vescovi, P., Merigo, E., Lo Re, G., Guglielmini, P., Di Fede, O., Campisi, G. & Bedogni, A., Aug 1 2015, In : Clinical Genitourinary Cancer. 13, 4, p. 287-294 8 p.

Research output: Contribution to journalArticle

Osteonecrosis
Diphosphonates
Jaw
Renal Cell Carcinoma
Multicenter Studies
62 Citations (Scopus)

Prognostic Role of PD-L1 Expression in Renal Cell Carcinoma. A Systematic Review and Meta-Analysis

Iacovelli, R., Nolè, F., Verri, E., Renne, G., Paglino, C., Santoni, M., Cossu Rocca, M., Giglione, P., Aurilio, G., Cullurà, D., Cascinu, S. & Porta, C., Oct 2 2015, (Accepted/In press) In : Targeted Oncology.

Research output: Contribution to journalArticle

Renal Cell Carcinoma
Meta-Analysis
Neoplasms
PubMed
MEDLINE

Sunitinib, Pazopanib or Sorafenib for the Treatment of Patients with Late Relapsing Metastatic Renal Cell Carcinoma

Santoni, M., Conti, A., Porta, C., Procopio, G., Sternberg, C. N., Basso, U., De Giorgi, U., Bracarda, S., Rizzo, M., Ortega, C., Massari, F., Iacovelli, R., Derosa, L., Masini, C., Milella, M., Di Lorenzo, G., Atzori, F., Pagano, M., Buti, S., De Vivo, R. & 11 others, Mosca, A., Rossi, M., Paglino, C., Verzoni, E., Cerbone, L., Muzzonigro, G., Falconi, M., Montironi, R., Burattini, L., Santini, D. & Cascinu, S., 2015, (Accepted/In press) In : Journal of Urology.

Research output: Contribution to journalArticle

Renal Cell Carcinoma
Disease-Free Survival
Neoplasm Metastasis
Recurrence
Survival
31 Citations (Scopus)

Sunitinib re-challenge in advanced renal-cell carcinoma.

Porta, C., Paglino, C. & Grünwald, V., 2014, In : British Journal of Cancer. 111, 6, p. 1047-1053 7 p.

Research output: Contribution to journalArticle

Renal Cell Carcinoma
Therapeutics
sunitinib
Sirolimus
Protein-Tyrosine Kinases
423 Citations (Scopus)

Targeting PI3K/Akt/mTOR signaling in cancer

Porta, C., Paglino, C. & Mosca, A., 2014, In : Frontiers in Oncology. 4 APR, Article 64.

Research output: Contribution to journalArticle

Phosphatidylinositol 3-Kinase
Sirolimus
Neoplasms
Cell Survival
Growth
2013
4 Citations (Scopus)

A retrospective analysis of two different sequences of therapy lines for advanced kidney cancer

Paglino, C., Procopio, G., Sabbatini, R., Bellmunt, J., Schmidinger, M., Bearz, A., Bamias, A., Melichar, B., Imarisio, I., Tinelli, C. & Porta, C., Nov 2013, In : Anticancer Research. 33, 11, p. 4999-5004 6 p.

Research output: Contribution to journalArticle

Kidney Neoplasms
Sirolimus
Disease-Free Survival
Therapeutics
sunitinib
26 Citations (Scopus)

Could interferon still play a role in metastatic renal cell carcinoma? A randomized study of two schedules of sorafenib plus interferon-alpha 2a (RAPSODY)

Bracarda, S., Porta, C., Boni, C., Santoro, A., Mucciarini, C., Pazzola, A., Cortesi, E., Gasparro, D., Labianca, R., Di Costanzo, F., Falcone, A., Cinquini, M., Caserta, C., Paglino, C. & De Angelis, V., Feb 2013, In : European Urology. 63, 2, p. 254-261 8 p.

Research output: Contribution to journalArticle

Renal Cell Carcinoma
Interferons
Appointments and Schedules
Arm
Disease-Free Survival
Immunology
Turtles
Kidney Neoplasms
Allergy and Immunology
Hope
2012
57 Citations (Scopus)

Changes in circulating pro-angiogenic cytokines, other than VEGF, before progression to sunitinib therapy in advanced renal cell carcinoma patients

Porta, C., Paglino, C., Imarisio, I., Ganini, C., Sacchi, L., Quaglini, S., Giunta, V. & De Amici, M., Dec 2012, In : Oncology. 84, 2, p. 115-122 8 p.

Research output: Contribution to journalArticle

Renal Cell Carcinoma
Vascular Endothelial Growth Factor A
Cytokines
Hepatocyte Growth Factor
Kidney Neoplasms
8 Citations (Scopus)

Lingual metastasis from renal cell carcinoma: A case report and literature review

Porta, C., Ganini, C., Lasagna, A., Ferraris, E., Gatti, P., Paglino, C., Imarisio, I., Morbini, P. & Benazzo, M., 2012, In : Rare Tumors. 4, 3, p. 130-133 4 p.

Research output: Contribution to journalArticle

Renal Cell Carcinoma
Tongue
Neoplasm Metastasis
Kidney
Deglutition Disorders
1 Citation (Scopus)

Modifying sunitinib schedule in advanced kidney cancer patients: Reflections from the results of the renal EFFECT trial

Porta, C., Ganini, C. & Paglino, C., 2012, In : Translational Andrology and Urology. 1, 2, p. 120-122 3 p.

Research output: Contribution to journalArticle

23 Citations (Scopus)

Primary resistance to tyrosine kinase inhibitors in patients with advanced renal cell carcinoma: State-of-the-science

Porta, C., Sabbatini, R., Procopio, G., Paglino, C., Galligioni, E. & Ortega, C., Dec 2012, In : Expert Review of Anticancer Therapy. 12, 12, p. 1571-1577 7 p.

Research output: Contribution to journalArticle

Renal Cell Carcinoma
Protein-Tyrosine Kinases
Therapeutics
Endothelial Growth Factors
6 Citations (Scopus)

Sorafenib rechalenge in metastatic renal cell carcinoma

Porta, C., Paglino, C. & Imarisio, I., Sep 2012, In : BJU International. 110, 6B

Research output: Contribution to journalArticle

9 Citations (Scopus)

Sunitinib in advanced metastatic non-clear cell renal cell carcinoma: A single institution retrospective study

Paglino, C., Imarisio, I., Ganini, C., Morbini, P., Vercelli, A., Bregant, C. & Porta, C., Dec 2012, In : Future Oncology. 8, 12, p. 1605-1612 8 p.

Research output: Contribution to journalArticle

Retrospective Studies
Renal Cell Carcinoma
Kidney Neoplasms
Disease-Free Survival
sunitinib
1 Citation (Scopus)
Kidney Neoplasms
Recurrence
Thalidomide
Nephrectomy
Patient Selection
8 Citations (Scopus)

The effect of sorafenib treatment on the diabetic status of patients with renal cell or hepatocellular carcinoma

Imarisio, I., Paglino, C., Ganini, C., Magnani, L., Caccialanza, R. & Porta, C., Aug 2012, In : Future Oncology. 8, 8, p. 1051-1057 7 p.

Research output: Contribution to journalArticle

Renal Cell Carcinoma
Hepatocellular Carcinoma
Prediabetic State
Diabetes Mellitus
Therapeutics
2011
31 Citations (Scopus)

Immunological effects of multikinase inhibitors for kidney cancer: A clue for integration with cellular therapies?

Porta, C., Paglino, C., Imarisio, I., Ganini, C. & Pedrazzoli, P., 2011, In : Journal of Cancer. 2, 1, p. 333-338 6 p.

Research output: Contribution to journalArticle

Kidney Neoplasms
Musculoskeletal Manipulations
Immune System
Therapeutics
Growth
3 Citations (Scopus)
Angiogenesis Inhibitors
Kidney Neoplasms
Immunotherapy
Immune System
Interleukin-6
27 Citations (Scopus)

Safety and treatment patterns of multikinase inhibitors in patients with metastatic renal cell carcinoma at a tertiary oncology center in Italy

Porta, C., Paglino, C., Imarisio, I., Canipari, C., Chen, K., Neary, M. & Duh, M. S., Mar 24 2011, In : BMC Cancer. 11, 105.

Research output: Contribution to journalArticle

Renal Cell Carcinoma
Italy
Safety
Asthenia
Therapeutics
67 Citations (Scopus)

Sequential use of sorafenib and sunitinib in advanced renal-cell carcinoma (RCC): An Italian multicentre retrospective analysis of 189 patient cases

Porta, C., Procopio, G., Cartenì, G., Sabbatini, R., Bearz, A., Chiappino, I., Ruggeri, E. M., Re, G. L., Ricotta, R., Zustovich, F., Landi, L., Calcagno, A., Imarisio, I., Verzoni, E., Rizzo, M., Paglino, C., Guadalupi, V. & Bajetta, E., Oct 2011, In : BJU International. 108, 8 B

Research output: Contribution to journalArticle

Renal Cell Carcinoma
Disease-Free Survival
Protein-Tyrosine Kinases
Confidence Intervals
Therapeutics
3 Citations (Scopus)
2010
6 Citations (Scopus)

Editorial: Sequencing or not sequencing multikinase inhibitors in kidney cancer: This is the dilemma

Paglino, C. & Porta, C., Mar 2010, In : Oncology Reviews. 4, 1, p. 1-3 3 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

Medical treatment of unresectable hepatocellular carcinoma: Going beyond sorafenib

Porta, C. & Paglino, C., 2010, In : World Journal of Hepatology. 2, 3, p. 103-113 11 p.

Research output: Contribution to journalArticle

Hepatocellular Carcinoma
Aurora Kinases
Catenins
Retinoic Acid Receptors
Vascular Endothelial Growth Factor Receptor
80 Citations (Scopus)
Kidney Neoplasms
Vascular Endothelial Growth Factor A
Disease-Free Survival
Serum
Renal Cell Carcinoma
20 Citations (Scopus)
Kidney Neoplasms
Protein-Tyrosine Kinases
Renal Cell Carcinoma
Retrospective Studies
Placebos
14 Citations (Scopus)

Sorafenib tosylate in advanced kidney cancer: Past, present and future

Porta, C., Paglino, C., Imarisio, I. & Ferraris, E., Jul 2009, In : Anti-Cancer Drugs. 20, 6, p. 409-415 7 p.

Research output: Contribution to journalArticle

Kidney Neoplasms
Platelet-Derived Growth Factor Receptors
Vascular Endothelial Growth Factor Receptor
Protein-Serine-Threonine Kinases
Publications
13 Citations (Scopus)

Use of sorafenib in two metastatic renal cell cancer patients with end-stage renal impairment undergoing replacement hemodialysis

Ferraris, E., Di Cesare, P., Lasagna, A., Paglino, C., Imarisio, I. & Porta, C., 2009, In : Tumori. 95, 4, p. 542-544 3 p.

Research output: Contribution to journalArticle

Renal Cell Carcinoma
Renal Dialysis
Kidney
Dialysis
Pharmacokinetics
2008
102 Citations (Scopus)

Circulating interleukin-6 as a tumor marker for hepatocellular carcinoma

Porta, C., De Amici, M., Quaglini, S., Paglino, C., Tagliani, F., Boncimino, A., Moratti, R. & Corazza, G. R., Feb 2008, In : Annals of Oncology. 19, 2, p. 353-358 6 p.

Research output: Contribution to journalArticle

Fetal Proteins
Tumor Biomarkers
Hepatocellular Carcinoma
Interleukin-6
Sensitivity and Specificity
1 Citation (Scopus)
Kidney Neoplasms
Nephrons
Lymphocyte Subsets
Nephrectomy
Renal Cell Carcinoma
1 Citation (Scopus)

Prognostic factors in advanced renal cell cancer

Porta, C., Imarisio, I., Paglino, C., Ferraris, E., Mensi, M. & Rovereto, B., Oct 2008, In : European Journal of Cancer, Supplement. 6, 14, p. 35-37 3 p.

Research output: Contribution to journalArticle

Renal Cell Carcinoma
Proteomics
Molecular Biology
Clinical Trials
Recurrence
36 Citations (Scopus)

Ranpirnase and its potential for the treatment of unresectable malignant mesothelioma

Porta, C., Paglino, C. & Mutti, L., 2008, In : Biologics: Targets and Therapy. 2, 4, p. 601-609 9 p.

Research output: Contribution to journalArticle

Doxorubicin
Ribonucleases
Therapeutics
RNA Cleavage
Maximum Tolerated Dose
2007
24 Citations (Scopus)
Kidney Neoplasms
Immunotherapy
cancer
Cytokines
Atlantic Ocean
6 Citations (Scopus)

Epidemiology, molecular epidemiology, and risk factors for renal cell carcinoma

Paglino, C., Imarisio, I. & Rovereto, B., Sep 2007, In : Oncology Reviews. 1, 2, p. 120-127 8 p.

Research output: Contribution to journalArticle

Molecular Epidemiology
Renal Cell Carcinoma
Epidemiology
Neoplasms
Incidence
20 Citations (Scopus)

Renal cell carcinoma-induced immunosuppression: An immunophenotypic study of lymphocyte subpopulations and circulating dendritic cells

Porta, C., Bonomi, L., Lillaz, B., Paglino, C., Rovati, B., Imarisio, I., Morbini, P., Villa, C., Danova, M., Mensi, M. & Rovereto, B., Jan 2007, In : Anticancer Research. 27, 1 A, p. 165-174 10 p.

Research output: Contribution to journalArticle

Lymphocyte Subsets
Renal Cell Carcinoma
Immunosuppression
Dendritic Cells
Lymphocytes
113 Citations (Scopus)
Antineoplastic Agents
Toxicity
Skin
Esophagitis
Kidney Neoplasms
2005
7 Citations (Scopus)

Pro-neoangiogenic cytokines (VEGF and bFGF) and anemia in solid tumor patients.

Porta, C., Imarisio, I., De Amici, M., Bonomi, L., Paglino, C., Biscaldi, E., Zimatore, M., Sartore-Bianchi, A., Danova, M., Moratti, R. & Riccardi, A., Apr 2005, In : Oncology Reports. 13, 4, p. 689-695 7 p.

Research output: Contribution to journalArticle

Vascular Endothelial Growth Factor A
Anemia
Cytokines
Neoplasms
Hemoglobins
50 Citations (Scopus)

Raltitrexed-Oxaliplatin combination chemotherapy is inactive as second-line treatment for malignant pleural mesothelioma patients

Porta, C., Zimatore, M., Bonomi, L., Imarisio, I., Paglino, C., Sartore-Bianchi, A. & Mutti, L., Jun 2005, In : Lung Cancer. 48, 3, p. 429-434 6 p.

Research output: Contribution to journalArticle

oxaliplatin
Combination Drug Therapy
Therapeutics
Drug Therapy
Survival