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Research Output 2017 2019

2019

Longevity-Associated Variant of BPIFB4 Mitigates Monocyte-Mediated Acquired Immune Response

Ciaglia, E., Montella, F., Maciag, A., Scala, P., Ferrario, A., Banco, C., Carrizzo, A., Spinelli, C. C., Cattaneo, M., De Candia, P., Vecchione, C., Villa, F. & Puca, A. A., 2019, In : Journals of Gerontology - Series A Biological Sciences and Medical Sciences. 74, p. S38-S44

Research output: Contribution to journalArticle

2018
Permeability
permeability
genome
Nitric oxide
nitric oxide

Innate immunity and cellular senescence: The good and the bad in the developmental and aged brain

Santoro, A., Spinelli, C. C., Martucciello, S., Nori, S. L., Capunzo, M., Puca, A. A. & Ciaglia, E., Mar 1 2018, In : Journal of Leukocyte Biology. 103, 3, p. 509-524 16 p.

Research output: Contribution to journalReview article

Cell Aging
Innate Immunity
Brain
Physiological Phenomena
Lymphatic System
2017

A rare genetic variant of BPIFB4 predisposes to high blood pressure via impairment of nitric oxide signaling

Vecchione, C., Villa, F., Carrizzo, A., Spinelli, C. C., Damato, A., Ambrosio, M., Ferrario, A., Madonna, M., Uccellatore, A., Lupini, S., Maciag, A., Ryskalin, L., Milanesi, L., Frati, G., Sciarretta, S., Bellazzi, R., Genovese, S., Ceriello, A., Auricchio, A., Malovini, A. & 1 others, Puca, A. A., 2017, In : Scientific Reports. 7, 1

Research output: Contribution to journalArticle

A rare genetic variant of BPIFB4 predisposes to high blood pressure via impairment of nitric oxide signaling

Vecchione, C., Villa, F., Carrizzo, A., Spinelli, C. C., Damato, A., Ambrosio, M., Ferrario, A., Madonna, M., Uccellatore, A., Lupini, S., Maciag, A., Ryskalin, L., Milanesi, L., Frati, G., Sciarretta, S., Bellazzi, R., Genovese, S., Ceriello, A., Auricchio, A., Malovini, A. & 1 others, Puca, A. A., Aug 29 2017, In : Scientific Reports. 7, 1, p. 9706

Research output: Contribution to journalArticle

Nitric Oxide
Blood Pressure
Hypertension
Nitric Oxide Synthase Type III
Gene Frequency

A rare genetic variant of BPIFB4 predisposes to high blood pressure via impairment of nitric oxide signaling

Vecchione, C., Villa, F., Carrizzo, A., Spinelli, C. C., Damato, A., Ambrosio, M., Ferrario, A., Madonna, M., Uccellatore, A., Lupini, S., Maciag, A., Ryskalin, L., Milanesi, L., Frati, G., Sciarretta, S., Bellazzi, R., Genovese, S., Ceriello, A., Auricchio, A., Malovini, A. & 1 others, Puca, A. A., Dec 1 2017, In : Scientific Reports. 7, 1, 9706.

Research output: Contribution to journalArticle

Nitric Oxide
Blood Pressure
Hypertension
Nitric Oxide Synthase Type III
Gene Frequency

Centenarians as a model to discover genetic and epigenetic signatures of healthy ageing

Puca, A. A., Spinelli, C., Accardi, G., Villa, F. & Caruso, C., Jan 1 2017, (Accepted/In press) In : Mechanisms of Ageing and Development.

Research output: Contribution to journalArticle

Epigenomics
Chromatin
Parents
Phenotype

Intra-fraction respiratory motion and baseline drift during breast Helical Tomotherapy

Ricotti, R., Ciardo, D., Fattori, G., Leonardi, M. C., Morra, A., Dicuonzo, S., Rojas, D. P., Pansini, F., Cambria, R., Cattani, F., Gianoli, C., Spinelli, C., Riboldi, M., Baroni, G., Orecchia, R. & Jereczek-Fossa, B. A., 2017, In : Radiotherapy and Oncology. 122, 1, p. 79-86 8 p.

Research output: Contribution to journalArticle

LAV-BPIFB4 isoform modulates eNOS signalling through Ca2+/PKC-alpha-dependent mechanism

Spinelli, C. C., Carrizzo, A., Ferrario, A., Villa, F., Damato, A., Ambrosio, M., Madonna, M., Frati, G., Fucile, S., Sciaccaluga, M., Capunzo, M., Calì, G., Milanesi, L., Maciag, A., Puca, A. A. & Vecchione, C., 2017, In : Cardiovascular Research. 113, 7, p. 795-804 10 p.

Research output: Contribution to journalArticle

LAV-BPIFB4 isoform modulates eNOS signalling through Ca2+/PKC-alpha-dependent mechanism

Spinelli, C. C., Carrizzo, A., Ferrario, A., Villa, F., Damato, A., Ambrosio, M., Madonna, M., Frati, G., Fucile, S., Sciaccaluga, M., Capunzo, M., Calì, G., Milanesi, L., Maciag, A., Puca, A. A. & Vecchione, C., Jan 1 2017, In : Cardiovascular Research. 113, 7, p. 795-804 10 p.

Research output: Contribution to journalArticle

Protein Kinase C-alpha
Nitric Oxide Synthase Type III
Permeability
Protein Isoforms
Endothelium

Motor phenotype is not associated with vascular dysfunction in symptomatic Huntington's disease transgenic R6/2 (160 CAG) mice

Di Pardo, A., Carrizzo, A., Damato, A., Castaldo, S., Amico, E., Capocci, L., Ambrosio, M., Pompeo, F., De Sanctis, C., Spinelli, C. C., Puca, A. A., Remondelli, P., Maglione, V. & Vecchione, C., Feb 17 2017, In : Scientific Reports. 7, 42797.

Research output: Contribution to journalArticle

Huntington Disease
Blood Vessels
Phenotype
Myography
Pathology

Motor phenotype is not associated with vascular dysfunction in symptomatic Huntington's disease transgenic R6/2 (160 CAG) mice

Di Pardo, A. D., Carrizzo, A., Damato, A., Castaldo, S., Amico, E., Capocci, L., Ambrosio, M., Pompeo, F., De Sanctis, C., Spinelli, C. C., Puca, A. A., Remondelli, P., Maglione, V. & Vecchione, C., 2017, In : Scientific Reports. 7

Research output: Contribution to journalArticle

Rac1 pharmacological inhibition rescues human endothelial dysfunction

Carrizzo, A., Vecchione, C., Damato, A., di Nonno, F., Ambrosio, M., Pompeo, F., Cappello, E., Capocci, L., Peruzzi, M., Valenti, V., Biondi-Zoccai, G., Antonino, A. G., Palmerio, S., Carnevale, R., Spinelli, C. C., Puca, A. A., Rubattu, S., Volpe, M., Sadoshima, J., Frati, G. & 1 others, Sciarretta, S., Jan 1 2017, In : Journal of the American Heart Association. 6, 3, e004746.

Research output: Contribution to journalArticle

Saphenous Vein
Adenine
Nicotine
Vasodilation
Pharmacology

Rac1 Pharmacological Inhibition Rescues Human Endothelial Dysfunction

Carrizzo, A., Vecchione, C., Damato, A., di Nonno, F., Ambrosio, M., Pompeo, F., Cappello, E., Capocci, L., Peruzzi, M., Valenti, V., Biondi-Zoccai, G., Marullo, A. G. M., Palmerio, S., Carnevale, R., Spinelli, C. C., Puca, A. A., Rubattu, S., Volpe, M., Sadoshima, J., Frati, G. & 1 others, Sciarretta, S., Feb 28 2017, In : Journal of the American Heart Association. 6, 3

Research output: Contribution to journalArticle

Saphenous Vein
Adenine
Nicotine
Vasodilation
Pharmacology

Rac1 Pharmacological Inhibition Rescues Human Endothelial Dysfunction

Carrizzo, A., Vecchione, C., Damato, A., di Nonno, F., Ambrosio, M., Pompeo, F., Cappello, E., Capocci, L., Peruzzi, M., Valenti, V., Biondi-Zoccai, G., Marullo, A. G. M., Palmerio, S., Carnevale, R., Spinelli, C. C., Puca, A. A., Rubattu, S., Volpe, M., Sadoshima, J., Frati, G. & 1 others, Sciarretta, S., Feb 28 2017, In : Journal of the American Heart Association. 6, 3

Research output: Contribution to journalArticle

Saphenous Vein
Adenine
Nicotine
Vasodilation
Pharmacology
Italy
Vascular Endothelial Growth Factor A
Health
Health Status
Ischemia

The expression of the BPIFB4 and CXCR4 associates with sustained health in long-living individuals from Cilento-Italy

Spinetti, G., Sangalli, E., Specchia, C., Villa, F., Spinelli, C., Pipolo, R., Carrizzo, A., Greco, S., Voellenkle, C., Vecchione, C., Madeddu, P., Martelli, F. & Puca, A. A., 2017, In : Aging. 9, 2, p. 370-380 11 p.

Research output: Contribution to journalArticle

Italy
Vascular Endothelial Growth Factor A
Health
Health Status
Ischemia