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Research Output 1994 2019

  • 3158 Citations
  • 27 h-Index
  • 56 Article
  • 3 Review article
  • 1 Conference contribution
  • 1 Comment/debate
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Article
2019

Cell communication and signaling: how to turn bad language into positive one

Chiodoni, C., Di Martino, M. T., Zazzeroni, F., Caraglia, M., Donadelli, M., Meschini, S., Leonetti, C. & Scotlandi, K., Mar 13 2019, In : Journal of Experimental and Clinical Cancer Research. 38, 1, p. 1-11 11 p.

Research output: Contribution to journalArticle

Cell Communication
Language
Neoplasms
Epithelial-Mesenchymal Transition
Tumor Microenvironment

Immune checkpoint ligand reverse signaling: Looking back to go forward in cancer therapy

Lecis, D., Sangaletti, S., Colombo, M. P. & Chiodoni, C., May 2019, In : Cancers. 11, 5, 624.

Research output: Contribution to journalArticle

Open Access
Ligands
Neoplasms
Therapeutics
Renal Cell Carcinoma
Non-Small Cell Lung Carcinoma

Phenethyl isothiocyanate hampers growth and progression of HER2-positive breast and ovarian carcinoma by targeting their stem cell compartment

Koschorke, A., Faraci, S., Giani, D., Chiodoni, C., Iorio, E., Canese, R., Colombo, M. P., Lamolinara, A., Iezzi, M., Ladomery, M., Vernieri, C., de Braud, F., Di Nicola, M., Tagliabue, E., Castagnoli, L. & Pupa, S. M., Dec 1 2019, In : Cellular Oncology. 42, 6, p. 815-828 14 p.

Research output: Contribution to journalArticle

SPARC is a new myeloid-derived suppressor cell marker licensing suppressive activities

Sangaletti, S., Talarico, G., Chiodoni, C., Cappetti, B., Botti, L., Portararo, P., Gulino, A., Consonni, F. M., Sica, A., Randon, G., Nicola, M. D., Tripodo, C. & Colombo, M. P., Jan 1 2019, In : Frontiers in Immunology. 10, JUN, 1369.

Research output: Contribution to journalArticle

Open Access
Licensure
Cysteine
Proteins
Epithelial-Mesenchymal Transition
NF-kappa B

WNT signaling modulates PD-L1 expression in the stem cell compartment of triple-negative breast cancer

Castagnoli, L., Cancila, V., Cordoba-Romero, S. L., Faraci, S., Talarico, G., Belmonte, B., Iorio, M. V., Milani, M., Volpari, T., Chiodoni, C., Hidalgo-Miranda, A., Tagliabue, E., Tripodo, C., Sangaletti, S., Di Nicola, M. & Pupa, S. M., May 23 2019, In : Oncogene. 38, 21, p. 4047-4060 14 p.

Research output: Contribution to journalArticle

Triple Negative Breast Neoplasms
Stem Cells
Neoplasms
Aldehyde Dehydrogenase
Spinocerebellar Ataxias
2018

CIAP1 regulates the EGFR/Snai2 axis in triple-negative breast cancer cells

Majorini, M. T., Manenti, G., Mano, M., De Cecco, L., Conti, A., Pinciroli, P., Fontanella, E., Tagliabue, E., Chiodoni, C., Colombo, M. P., Delia, D. & Lecis, D., 2018, In : Cell Death and Differentiation. 25, 12, p. 2147-2164 18 p.

Research output: Contribution to journalArticle

Cross-Talk between Myeloid-Derived Suppressor Cells and Mast Cells Mediates Tumor-Specific Immunosuppression in Prostate Cancer

Jachetti, E., Cancila, V., Rigoni, A., Bongiovanni, L., Cappetti, B., Belmonte, B., Enriquez, C., Casalini, P., Ostano, P., Frossi, B., Sangaletti, S., Chiodoni, C., Chiorino, G., Pucillo, C. E., Tripodo, C. & Colombo, M. P., May 2018, In : Cancer immunology research. 6, 5, p. 552-565 14 p.

Research output: Contribution to journalArticle

Mast Cells
Immunosuppression
Prostatic Neoplasms
Adenocarcinoma
Prostate

Reprogramming Tumor-Immune Cell Interface in Solid and Hematological Malignancies to Enhance Response to Therapy

Di Martino, M. T., Zazzeroni, F., Donadelli, M., Chiodoni, C., Caraglia, M., Scotlandi, K., Meschini, S. & Leonetti, C., Mar 5 2018, In : Journal of experimental & clinical cancer research : CR. 37, 1, p. 48

Research output: Contribution to journalArticle

2017

Imatinib Spares cKit-Expressing Prostate Neuroendocrine Tumors, whereas Kills Seminal Vesicle Epithelial-Stromal Tumors by Targeting PDGFR-beta.

Jachetti, E., Rigoni, A., Bongiovanni, L., Arioli, I., Botti, L., Parenza, M., Cancila, V., Chiodoni, C., Festinese, F., Bellone, M., Tardanico, R., Tripodo, C. & Colombo, M. P., Feb 1 2017, In : Molecular Cancer Therapeutics. 16, 2, p. 365-375 11 p.

Research output: Contribution to journalArticle

Imatinib spares cKit-expressing prostate neuroendocrine tumors, whereas kills seminal vesicle epithelial-stromal tumors by targeting PDGFR-β

Jachetti, E., Rigoni, A., Bongiovanni, L., Arioli, I., Botti, L., Parenza, M., Cancila, V., Chiodoni, C., Festinese, F., Bellone, M., Tardanico, R., Tripodo, C. & Colombo, MP., 2017, In : Molecular Cancer Therapeutics. 16, 2, p. 365-375 11 p.

Research output: Contribution to journalArticle

Neuroendocrine Tumors
Seminal Vesicles
Prostate
Prostatic Neoplasms
Mast Cells

Pathobiological implications of the d16HER2 splice variant for stemness and aggressiveness of HER2-positive breast cancer

Castagnoli, L., Ghedini, G. C., Koschorke, A., Triulzi, T., Dugo, M., Gasparini, P., Casalini, P., Palladini, A., Iezzi, M., Lamolinara, A., Lollini, P. L., Nanni, P., Chiodoni, C., Tagliabue, E. & Pupa, S. M., Mar 23 2017, In : Oncogene. 36, 12, p. 1721-1732 12 p.

Research output: Contribution to journalArticle

Breast Neoplasms
Transgenic Mice
Anoikis
Spinocerebellar Ataxias
Neoplasms

Persistent immune stimulation exacerbates genetically driven myeloproliferative disorders via stromal remodeling

Tripodo, C., Burocchi, A., Piccaluga, P. P., Chiodoni, C., Portararo, P., Cappetti, B., Botti, L., Gulino, A., Isidori, A., Liso, A., Visani, G., Martelli, M. P., Falini, B., Pandolfi, P. P., Colombo, M. P. & Sangaletti, S., Jul 1 2017, In : Cancer Research. 77, 13, p. 3685-3699 15 p.

Research output: Contribution to journalArticle

Myeloproliferative Disorders
Bone Marrow
Acute Myeloid Leukemia
Extracellular Matrix
Animal Models

Trabectedin overrides osteosarcoma differentiative block and reprograms the tumor immune environment enabling effective combination with immune checkpoint inhibitors

Ratti, C., Botti, L., Cancila, V., Galvan, S., Torselli, I., Garofalo, C., Manara, M. C., Bongiovanni, L., Valenti, C. F., Burocchi, A., Parenza, M., Cappetti, B., Sangaletti, S., Tripodo, C., Scotlandi, K., Colombo, M. P. & Chiodoni, C., Sep 1 2017, In : Clinical Cancer Research. 23, 17, p. 5149-5161 13 p.

Research output: Contribution to journalArticle

trabectedin
Osteosarcoma
Neoplasms
Lung
Neoplasm Metastasis

Trabectedin Overrides Osteosarcoma Differentiative Block and Reprograms the Tumor Immune Environment Enabling Effective Combination with Immune Checkpoint Inhibitors

Ratti, C., Botti, L., Cancila, V., Galvan, S., Torselli, I., Garofalo, C., Manara, M. C., Bongiovanni, L., Valenti, C. F., Burocchi, A., Parenza, M., Cappetti, B., Sangaletti, S., Tripodo, C., Scotlandi, K., Colombo, M. P. & Chiodoni, C., Sep 1 2017, In : Clinical Cancer Research. 23, 17, p. 5149-5161 13 p.

Research output: Contribution to journalArticle

trabectedin
Osteosarcoma
Neoplasms
Lung
Neoplasm Metastasis

Trabectedin Overrides Osteosarcoma Differentiative Block and Reprograms the Tumor Immune Environment Enabling Effective Combination with Immune Checkpoint Inhibitors.

Ratti, C., Botti, L., Cancila, V., Galvan, S., Torselli, I., Garofalo, C., Manara, M. C., Bongiovanni, L., Valenti, C. F., Burocchi, A., Parenza, M., Cappetti, B., Sangaletti, S., Tripodo, C., Scotlandi, K., Colombo, M. P. & Chiodoni, C., Jun 9 2017, In : Clinical Cancer Research. 23, 17, p. 5149-5161 13 p.

Research output: Contribution to journalArticle

trabectedin
Osteosarcoma
Neoplasms
Lung
Neoplasm Metastasis
2016

Healthy and tumoral tissue resistivity in wild-type and sparc–/– animal models

Meroni, D., Mauri, G., Bovio, D., Bianchi, A. M., Chiodoni, C., Colombo, M. P., Meroni, E. & Aliverti, A., Apr 21 2016, (Accepted/In press) In : Medical and Biological Engineering and Computing. p. 1-9 9 p.

Research output: Contribution to journalArticle

Tumors
Animals
Oils and fats
Tissue
Bearings (structural)

Mesenchymal Transition of High-Grade Breast Carcinomas Depends on Extracellular Matrix Control of Myeloid Suppressor Cell Activity

Sangaletti, S., Tripodo, C., Santangelo, A., Castioni, N., Portararo, P., Gulino, A., Botti, L., Parenza, M., Cappetti, B., Orlandi, R., Tagliabue, E., Chiodoni, C. & Colombo, M. P., Sep 27 2016, In : Cell Reports. 17, 1, p. 233-248 16 p.

Research output: Contribution to journalArticle

Epithelial-Mesenchymal Transition
Myeloid Cells
Extracellular Matrix
Tumors
Breast Neoplasms

TNF-related apoptosis-inducing ligand (trail)-armed exosomes deliver proapoptotic signals to tumor site

Rivoltini, L., Chiodoni, C., Squarcina, P., Tortoreto, M. L., Villa, A., Vergani, B., Bürdek, M., Botti, L., Arioli, I., Cova, A., Mauri, G., Vergani, E., Bianchi, B., Mina, P. D., Cantone, L., Bollati, V., Zaffaroni, N., Gianni, A. M., Colombo, M. P. & Huber, V., Jul 15 2016, In : Clinical Cancer Research. 22, 14, p. 3499-3512 14 p.

Research output: Contribution to journalArticle

TNF-Related Apoptosis-Inducing Ligand
Exosomes
Neoplasms
TNF-Related Apoptosis-Inducing Ligand Receptors
Necrosis

TNF-related apoptosis-inducing ligand (trail)-armed exosomes deliver proapoptotic signals to tumor site

Rivoltini, L., Chiodoni, C., Squarcina, P., Tortoreto, M., Villa, A., Vergani, B., Bürdek, M., Botti, L., Arioli, I., Cova, A., Mauri, G., Vergani, E., Bianchi, B., Mina, P. D., Cantone, L., Bollati, V., Zaffaroni, N., Gianni, A. M., Colombo, M. P. & Huber, V., Jul 15 2016, In : Clinical Cancer Research. 22, 14, p. 3499-3512 14 p.

Research output: Contribution to journalArticle

TNF-Related Apoptosis-Inducing Ligand
Exosomes
Neoplasms
TNF-Related Apoptosis-Inducing Ligand Receptors
Necrosis
2015

CD99 triggering in Ewing sarcoma delivers a lethal signal through p53 pathway reactivation and cooperates with doxorubicin

Guerzoni, C., Fiori, V., Terracciano, M., Manara, M. C., Moricoli, D., Pasello, M., Sciandra, M., Nicoletti, G., Gellini, M., Dominici, S., Chiodoni, C., Fornasari, P. M., Lollini, P. L., Colombo, M. P., Picci, P., Cianfriglia, M., Magnani, M. & Scotlandi, K., Jan 1 2015, In : Clinical Cancer Research. 21, 1, p. 146-156 11 p.

Research output: Contribution to journalArticle

Ewing's Sarcoma
Doxorubicin
Cell Death
Single-Chain Antibodies
Mesenchymal Stromal Cells

SOCS2 controls proliferation and stemness of hematopoietic cells under stress conditions and its deregulation marks unfavorable acute leukemias

Vitali, C., Bassani, C., Chiodoni, C., Fellini, E., Guarnotta, C., Miotti, S., Sangaletti, S., Fuligni, F., De Cecco, L., Piccaluga, P. P., Colombo, M. P. & Tripodo, C., Jun 1 2015, In : Cancer Research. 75, 11, p. 2387-2399 13 p.

Research output: Contribution to journalArticle

Hematopoietic Stem Cells
Leukemia
Hematopoiesis
Fluorouracil
Thrombopoietin

The ins and outs of osteopontin

Chiodoni, C., Sangaletti, S., Tripodo, C. & Colombo, M. P., 2015, In : OncoImmunology. 4, 3, p. 1-2 2 p.

Research output: Contribution to journalArticle

Osteopontin
Extracellular Matrix Proteins
Immunosuppression
Neoplasms
Breast Neoplasms
2014

Activated d16HER2 homodimers and src kinase mediate optimal efficacy for trastuzumab

Castagnoli, L., Iezzi, M., Ghedini, G. C., Ciravolo, V., Marzano, G., Lamolinara, A., Zappasodi, R., Gasparini, P., Campiglio, M., Amici, A., Chiodoni, C., Palladini, A., Lollini, P. L., Triulzi, T., Menard, S., Nanni, P., Tagliabue, E. & Pupa, S. M., Nov 1 2014, In : Cancer Research. 74, 21, p. 6248-6259 12 p.

Research output: Contribution to journalArticle

src-Family Kinases
Breast Neoplasms
Transgenic Mice
Exons
Protein Isoforms

Expression levels of insulin receptor substrate-1 modulate the osteoblastic differentiation of mesenchymal stem cells and osteosarcoma cells

Contaldo, C., Myers, T. J., Zucchini, C., Manara, M. C., Chiodoni, C., Colombo, M. P., Nicoletti, G., Lollini, P. L., Li, T., Longobardi, L., Scotlandi, K. & Spagnoli, A., Feb 2014, In : Growth Factors. 32, 1, p. 41-53 13 p.

Research output: Contribution to journalArticle

Insulin Receptor Substrate Proteins
Osteosarcoma
Stem cells
Mesenchymal Stromal Cells
Proteasome Inhibitors

Osteopontin shapes immunosuppression in the metastatic niche

Sangaletti, S., Tripodo, C., Sandri, S., Torselli, I., Vitali, C., Ratti, C., Botti, L., Burocchi, A., Porcasi, R., Tomirotti, A., Colombo, M. P. & Chiodoni, C., Sep 1 2014, In : Cancer Research. 74, 17, p. 4706-4719 14 p.

Research output: Contribution to journalArticle

Osteopontin
Immunosuppression
Neoplasms
Myeloid Cells
Lung

Stromal niche communalities underscore the contribution of the matricellular protein SPARC to B-cell development and lymphoid malignancies

Sangaletti, S., Tripodo, C., Portararo, P., Dugo, M., Vitali, C., Botti, L., Guarnotta, C., Cappetti, B., Gulino, A., Torselli, I., Casalini, P., Chiodoni, C. & Colombo, M. P., 2014, In : OncoImmunology. 3, 6, e28989.

Research output: Contribution to journalArticle

Cysteine
B-Lymphocytes
Bone Marrow
Germinal Center
Lymphopoiesis

Suppression of Invasion and Metastasis of Triple-Negative Breast Cancer Lines by Pharmacological or Genetic Inhibition of Slug Activity

Ferrari-Amorotti, G., Chiodoni, C., Shen, F., Cattelani, S., Soliera, A. R., Manzotti, G., Grisendi, G., Dominici, M., Rivasi, F., Colombo, M. P., Fatatis, A. & Calabretta, B., 2014, In : Neoplasia (United States). 16, 12, p. 1047-1058 12 p.

Research output: Contribution to journalArticle

Triple Negative Breast Neoplasms
Gastropoda
Tranylcypromine
Pharmacology
Neoplasm Metastasis
2013

Inhibiting interactions of lysine demethylase LSD1 with snail/slug blocks cancer cell invasion

Ferrari-Amorotti, G., Fragliasso, V., Esteki, R., Prudente, Z., Soliera, A. R., Cattelani, S., Manzotti, G., Grisendi, G., Dominici, M., Pieraccioli, M., Raschellà, G., Chiodoni, C., Colombo, M. P. & Calabretta, B., Jan 1 2013, In : Cancer Research. 73, 1, p. 235-245 11 p.

Research output: Contribution to journalArticle

Gastropoda
Snails
Lysine
Neoplasms
Tranylcypromine

Ultrasound-guided intra-tumor injection of combined immunotherapy cures mice from orthotopic prostate cancer

Mauri, G., Chiodoni, C., Parenza, M., Arioli, I., Tripodo, C. & Colombo, M. P., Dec 2013, In : Cancer Immunology, Immunotherapy. 62, 12, p. 1811-1819 9 p.

Research output: Contribution to journalArticle

Immunotherapy
Prostatic Neoplasms
Injections
T-Lymphocytes
Neoplasms
2012

Neutrophil extracellular traps mediate transfer of cytoplasmic neutrophil antigens to myeloid dendritic cells toward ANCA induction and associated autoimmunity

Sangaletti, S., Tripodo, C., Chiodoni, C., Guarnotta, C., Cappetti, B., Casalini, P., Piconese, S., Parenza, M., Guiducci, C., Vitali, C. & Colombo, M. P., Oct 11 2012, In : Blood. 120, 15, p. 3007-3018 12 p.

Research output: Contribution to journalArticle

Antineutrophil Cytoplasmic Antibodies
Myeloid Cells
Autoimmunity
Dendritic Cells
Neutrophils

Stromal SPARC contributes to the detrimental fibrotic changes associated with myeloproliferation whereas its deficiency favors myeloid cell expansion

Tripodo, C., Sangaletti, S., Guarnotta, C., Piccaluga, P. P., Cacciatore, M., Giuliano, M., Franco, G., Chiodoni, C., Sciandra, M., Miotti, S., Calvaruso, G., Carè, A., Florena, A. M., Scotlandi, K., Orazi, A., Pileri, S. A. & Colombo, M. P., Oct 25 2012, In : Blood. 120, 17, p. 3541-3554 14 p.

Research output: Contribution to journalArticle

Thrombopoietin
Primary Myelofibrosis
Myeloid Cells
Fibrosis
Osteosclerosis
2011

SPARC oppositely regulates inflammation and fibrosis in bleomycin-induced lung damage

Sangaletti, S., Tripodo, C., Cappetti, B., Casalini, P., Chiodoni, C., Piconese, S., Santangelo, A., Parenza, M., Arioli, I., Miotti, S. & Colombo, M. P., Dec 2011, In : American Journal of Pathology. 179, 6, p. 3000-3010 11 p.

Research output: Contribution to journalArticle

Cysteine
Fibrosis
Inflammation
Lung
Proteins

The matricellular protein SPARC supports follicular dendritic cell networking toward Th17 responses

Piconese, S., Costanza, M., Tripodo, C., Sangaletti, S., Musio, S., Pittoni, P., Poliani, P. L., Burocchi, A., Passafaro, A. L., Gorzanelli, A., Vitali, C., Chiodoni, C., Barnaba, V., Pedotti, R. & Colombo, M. P., Dec 2011, In : Journal of Autoimmunity. 37, 4, p. 300-310 11 p.

Research output: Contribution to journalArticle

Follicular Dendritic Cells
Germinal Center
Th17 Cells
Extracellular Matrix
Proteins
2010

Matricellular proteins: From homeostasis to inflammation, cancer, and metastasis

Chiodoni, C., Colombo, M. P. & Sangaletti, S., Jun 2010, In : CANCER AND METASTASIS REVIEW. 29, 2, p. 295-307 13 p.

Research output: Contribution to journalArticle

Homeostasis
Neoplasm Metastasis
Inflammation
Neoplasms
Proteins

Oncogene-driven intrinsic inflammation induces leukocyte production of tumor necrosis factor that critically contributes to mammary carcinogenesis

Sangaletti, S., Tripodo, C., Ratti, C., Piconese, S., Porcasi, R., Salcedo, R., Trinchieri, G., Colombo, M. P. & Chiodoni, C., Oct 15 2010, In : Cancer Research. 70, 20, p. 7764-7775 12 p.

Research output: Contribution to journalArticle

Oncogenes
Carcinogenesis
Breast
Leukocytes
Tumor Necrosis Factor-alpha
2008

Macrophage-derived SPARC bridges tumor cell-extracellular matrix interactions toward metastasis

Sangaletti, S., Di Carlo, E., Gariboldi, S., Miotti, S., Cappetti, B., Parenza, M., Rumio, C., Brekken, R. A., Chiodoni, C. & Colombo, M. P., Nov 1 2008, In : Cancer Research. 68, 21, p. 9050-9059 10 p.

Research output: Contribution to journalArticle

Extracellular Matrix
Cysteine
Macrophages
Neoplasm Metastasis
Neoplasms
2006

Nucleofection is an efficient nonviral transfection technique for human bone marrow-derived mesenchymal stem cells

Aluigi, M., Fogli, M., Curti, A., Isidori, A., Gruppioni, E., Chiodoni, C., Colombo, M. P., Versura, P., D'Errico-Grigioni, A., Ferri, E., Baccarani, M. & Lemoli, R. M., Feb 2006, In : Stem Cells. 24, 2, p. 454-461 8 p.

Research output: Contribution to journalArticle

Mesenchymal Stromal Cells
Transfection
Bone Marrow
Transgenes
Technology

Triggering CD40 on endothelial cells contributes to tumor growth

Chiodoni, C., Iezzi, M., Guiducci, C., Sangaletti, S., Alessandrini, I., Ratti, C., Tiboni, F., Musiani, P., Granger, D. N. & Colombo, M. P., Oct 2006, In : Journal of Experimental Medicine. 203, 11, p. 2441-2450 10 p.

Research output: Contribution to journalArticle

Endothelial Cells
Growth
CD40 Ligand
Neoplasms
Blood Platelets
2005

Accelerated dendritic-cell migration and T-cell priming in SPARC-deficient mice

Sangaletti, S., Gioiosa, L., Guiducci, C., Rotta, G., Rescigno, M., Stoppacciaro, A., Chiodoni, C. & Colombo, M. P., Aug 15 2005, In : Journal of Cell Science. 118, 16, p. 3685-3694 10 p.

Research output: Contribution to journalArticle

Langerhans Cells
Dendritic Cells
Cell Movement
Cysteine
T-Lymphocytes

A DNA vaccine targeting survivin combines apoptosis with suppression of angiogenesis in lung tumor eradication

Xiang, R., Mizutani, N., Luo, Y., Chiodoni, C., Zhou, H., Mizutani, M., Ba, Y., Becker, J. C. & Reisfeld, R. A., Jan 15 2005, In : Cancer Research. 65, 2, p. 553-561 9 p.

Research output: Contribution to journalArticle

DNA Vaccines
Apoptosis
Lung
Neoplasms
Chemokine CCL21

Cancer immunotherapy based on killing of Salmonella-infected tumor cells

Avogadri, F., Martinoli, C., Petrovska, L., Chiodoni, C., Transidico, P., Bronte, V., Longhi, R., Colombo, M. P., Dougan, G. & Rescigno, M., May 1 2005, In : Cancer Research. 65, 9, p. 3920-3927 8 p.

Research output: Contribution to journalArticle

Salmonella
Immunotherapy
Neoplasms
Salmonella typhimurium
Cross-Priming

Interleukin-12 production by leukemia-derived dendritic cells counteracts the inhibitory effect of leukemic microenvironment on T cells

Curti, A., Pandolfi, S., Aluigi, M., Isidori, A., Alessandrini, I., Chiodoni, C., Testoni, N., Colombo, M. P., Baccarani, M. & Lemoli, R. M., Dec 2005, In : Experimental Hematology. 33, 12, p. 1521-1530 10 p.

Research output: Contribution to journalArticle

Interleukin-12
Acute Myeloid Leukemia
Dendritic Cells
Leukemia
T-Lymphocytes
2003
Myeloid Cells
Tumors
Hematopoiesis
Breast Neoplasms
Tumor Burden
2002

Antitumor effect of interleukin (IL)-12 in the absence of endogenous IFN-γ: A role for intrinsic tumor immunogenicity and IL-15

Gri, G., Chiodoni, C., Gallo, E., Stoppacciaro, A., Liew, F. Y. & Colombo, M. P., Aug 1 2002, In : Cancer Research. 62, 15, p. 4390-4397 8 p.

Research output: Contribution to journalArticle

Interleukin-15
Interleukin-12
Neoplasms
T-Lymphocytes
Interleukin-15 Receptors

IFN-γ-independent synergistic effects of IL-12 and IL-15 induce anti-tumor immune responses in syngeneic mice

Comes, A., Di Carlo, E., Musiani, P., Rosso, O., Meazza, R., Chiodoni, C., Colombo, M. P. & Ferrini, S., 2002, In : European Journal of Immunology. 32, 7, p. 1914-1923 10 p.

Research output: Contribution to journalArticle

Interleukin-15
Interleukin-12
Neoplasms
Granulocytes
Natural Killer Cells

Reversal of tumor-induced dendritic cell paralysis by CpG immunostimulatory oligonucleotide and anti-interleukin 10 receptor antibody

Vicari, A. P., Chiodoni, C., Vaure, C., Aït-Yahia, S., Dercamp, C., Matsos, F., Reynard, O., Taverne, C., Merle, P., Colombo, M. P., O'Garra, A., Trinchieri, G. & Caux, C., Aug 19 2002, In : Journal of Experimental Medicine. 196, 4, p. 541-549 9 p.

Research output: Contribution to journalArticle

Interleukin-10 Receptors
Oligonucleotides
Paralysis
Dendritic Cells
Antibodies
2001

Different requirements for α-galactosylceramide and recombinant IL-12 antitumor activity in the treatment of C-26 colon carcinoma hepatic metastases

Chiodoni, C., Stoppacciaro, A., Sangaletti, S., Gri, G., Cappetti, B., Koezuka, Y. & Colombo, M. P., 2001, In : European Journal of Immunology. 31, 10, p. 3101-3110 10 p.

Research output: Contribution to journalArticle

Galactosylceramides
Interleukin-12 Subunit p40
Interleukin-12
Knockout Mice
Colon
1999
CD40 Ligand
Cytotoxic T-Lymphocytes
Neoplasm Antigens
Granulocyte-Macrophage Colony-Stimulating Factor
Dendritic Cells
1998

HIV/gp120 and PMA/ionomycin induced apoptosis but not activation induced cell death require PKC for Fas-L upregulation

Accornero, P., Radrizzani, M., Carè, A., Mattia, G., Chiodoni, C., Kurrle, R. & Colombo, M. P., Oct 9 1998, In : FEBS Letters. 436, 3, p. 461-465 5 p.

Research output: Contribution to journalArticle

HIV Envelope Protein gp120
Ionomycin
Cell death
Protein Kinase C
Acetates

Human melanoma-reactive CD4+ and CD8+ CTL clones resist Fas ligand- induced apoptosis and use Fas/Fas ligand-independent mechanisms for tumor killing

Rivoltini, L., Radrizzani, M., Accornero, P., Squarcina, P., Chiodoni, C., Mazzocchi, A., Castelli, C., Tarsini, P., Viggiano, V., Belli, F., Colombo, M. P. & Parmiani, G., Aug 1 1998, In : Journal of Immunology. 161, 3, p. 1220-1230 11 p.

Research output: Contribution to journalArticle

Fas Ligand Protein
Melanoma
Clone Cells
Apoptosis
Neoplasms