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1998

Age-related changes of the 3'APOB-VNTR genotype pool in ageing cohorts

De Benedictis, G., Carotenuto, L., Carrieri, G., De Luca, M., Falcone, E., Rose, G., Yashin, A. I., Bonafè, M. & Franceschi, C., Mar 1998, In : Annals of Human Genetics. 62, 2, p. 115-122 8 p.

Research output: Contribution to journalArticle

Apoptosis by 2-chloro-2'-deoxy-adenosine and 2-chloro-adenosine in human peripheral blood mononuclear cells

Barbieri, D., Abbracchio, M. P., Salvioli, S., Monti, D., Cossarizza, A., Ceruti, S., Brambilla, R., Cattabeni, F., Jacobson, K. A. & Franceschi, C., May 1 1998, In : Neurochemistry International. 32, 5-6, p. 493-504 12 p.

Research output: Contribution to journalArticle

Apoptosis-like, reversible changes in plasma membrane asymmetry and permeability, and transient modifications in mitochondrial membrane potential induced by curcumin in rat thymocytes

Jaruga, E., Salvioli, S., Dobrucki, J., Chrul, S., Bandorowicz-Pikuła, J., Sikora, E., Franceschi, C., Cossarizza, A. & Bartosz, G., Aug 21 1998, In : FEBS Letters. 433, 3, p. 287-293 7 p.

Research output: Contribution to journalArticle

Assessment of sense of taste in Italian centenarians

Baggio, G., Dalla Vestra, M., Donazzan, S., Barbagallo Sangiorgi, G., Barbagallo, M., Frada, G., Bertolini, S., Agretti, M., Costelli, P., Bosi, E., Manzoni, M., Tomasello, F. B., Capurso, A., Colacicco, A. M., Solfrizzi, V., Fabris, F., Cappa, G., Ferrario, E., Forconi, S., Guerrini, M. & 40 others, Boschi, S., Franceschi, C., Cossarizza, A., Monti, D., Gaddi, A., D'Addato, S., Galletti, C., Giarelli, L., Cavalieri, F., Stanta, G., Mari, D., Duca, F., Ferrazzi, P., Marigliano, V., Bauco, C., Cacciafesta, M., Masotti, G., Marchionni, N., Petruzzi, E., Mattace, R., Motta, M., Pansini, L., Motta, L., Rapisarda, R., Receputo, G., Passeri, M., Fagnoni, F., Sansoni, P., Salvioli, G., Baldelli, M. V., Neri, M., Senin, U., Cherubini, A., Polidori, M. C., Trabucchi, M., Boffelli, S., Rozzini, R., Varricchio, M., Gambardella, A. & Paolisso, G., Mar 1998, In : Archives of Gerontology and Geriatrics. 26, 2, p. 177-183 7 p.

Research output: Contribution to journalArticle

Biology and genetics of human longetivity

Baggio, G., Franceschi, C., Mari, D., Herskind, A. M., Andersen-Ranberg, K. & Jeune, B., 1998, In : Australasian Journal on Ageing. 17, SUPPL. 1, p. 8-10 3 p.

Research output: Contribution to journalArticle

Congenital disorders sharing oxidative stress and cancer proneness as phenotypic hallmarks: Prospects for joint research in pharmacology

Pagano, G., Korkina, L. G., Brunk, U. T., Chessa, L., Degan, P., Del Principe, D., Kelly, F. J., Malorni, W., Pallardó, F., Pasquier, C., Scovassi, I., Zatterale, A. & Franceschi, C., Sep 1998, In : Medical Hypotheses. 51, 3, p. 253-266 14 p.

Research output: Contribution to journalArticle

Decrease in mitochondrial energy coupling by thyroid hormones: A physiological effect rather than a pathological hyperthyroidism consequence

Bobyleva, V., Pazienza, T. L., Maseroli, R., Tomasi, A., Salvioli, S., Cossarizza, A., Franceschi, C. & Skulachev, V. P., Jul 3 1998, In : FEBS Letters. 430, 3, p. 409-413 5 p.

Research output: Contribution to journalArticle

Gene/longevity association studies at four autosomal loci (REN, THO, PARP, SOD2)

De Benedictis, G., Carotenuto, L., Carrieri, G., De Luca, M., Falcone, E., Rose, G., Cavalcanti, S., Corsonello, F., Feraco, E., Baggio, G., Bertolini, S., Mari, D., Mattace, R., Yashin, A. I., Bonafè, M. & Franceschi, C., Nov 1998, In : European Journal of Human Genetics. 6, 6, p. 534-541 8 p.

Research output: Contribution to journalArticle

Growth properties and growth factor responsiveness in skin fibroblasts from centenarians

Tesco, G., Vergelli, M., Grassilli, E., Salomoni, P., Bellesia, E., Sikora, E., Radziszewska, E., Barbieri, D., Latorraca, S., Fagiolo, U., Santacaterina, S., Amaducci, L., Tiozzo, R., Franceschi, C. & Sorbi, S., Mar 27 1998, In : Biochemical and Biophysical Research Communications. 244, 3, p. 912-916 5 p.

Research output: Contribution to journalArticle

Immunosenescence

Franceschi, C., Passeri, M., De Benedictis, G. & Motta, L., 1998, In : Aging clinical and experimental research. 10, 2, p. 153-154 2 p.

Research output: Contribution to journalArticle

Inhibition of proteasome function prevents thymocyte apoptosis: Involvement of ornithine decarboxylase

Grassilli, E., Benatti, F., Dansi, P., Giammarioli, A. M., Malorni, W., Franceschi, C. & Desiderio, M. A., Sep 18 1998, In : Biochemical and Biophysical Research Communications. 250, 2, p. 293-297 5 p.

Research output: Contribution to journalArticle

International conference on biomedical aspects of aging research December 10-13, 1997 Fondazione Cini, San Giorgio, Venezia, Italy

Evans, J. G., Kirkwood, T. B. L., Hayflick, L., Austad, S. N., De Benedictis, G., Franceschi, C., Martin, G. M., Sohal, R. S., Orr, W. C., Levine, R. L., Cristofalo, V. J., Tresini, M., Effros, R. B., Passeri, M., Motta, L., Miller, R. A., Jackson, A., Chrisp, C., Galecki, A., Burke, D. & 56 others, Michel, J. P., Hyman, B. T., Schneider, L. S., Sorbi, S., Nacmias, B., Forleo, P., Zaidi, M., Kowal, J., Adami, S., McGowan, J. A., Dere, W. H., Blanchard, F., Papapoulos, S., Compston, J., Maggi, S., Lye, M., Marchionni, N., Di Bari, M., Innocenti, F., Chiarlone, M., Nardi, M., Fini, R., Masotti, G., Pedersen, T. R., Schroll, M., Zanchetti, A., Rich, M. W., Manzato, E., Brody, J. A., Grant, M. D., Frateschi, L. J., Miller, S. C., Zhang, H., Heikkinen, E., Andrews, G. R., Masoro, E. J., Bergamini, E., Cavallini, G., Cecchi, L., Donati, A., Dolfi, C., Gori, Z., Innocenti, B., Maccheroni, M., Marino, M., Masini, M., Paradiso, C., Pollera, M., Trentalance, A., Bellia, V., Tilvis, R., Johnson, B. D., Grassi, V., Cossi, S., Leonardi, R. & Tantucci, C., Apr 1998, In : Aging clinical and experimental research. 10, 2, p. 141-177 37 p.

Research output: Contribution to journalArticle

Lipoprotein(a) and lipoprotein profile in healthy centenarians: A reappraisal of vascular risk factors

Baggio, G., Donazzan, S., Monti, D., Mari, D., Martini, S., Gabelli, C., Vestra, M. D., Previato, L., Guido, M., Pigozzo, S., Cortella, I., Crepaldi, G. & Franceschi, C., 1998, In : FASEB Journal. 12, 6, p. 433-437 5 p.

Research output: Contribution to journalArticle

Mitochondrial membrane potential and DNA stainability in human sperm cells: A flow cytometry analysis with implications for male infertility

Troiano, L., Granata, A. R. M., Cossarizza, A., Kalashnikova, G., Bianchi, R., Pini, G., Tropea, F., Carani, C. & Franceschi, C., Jun 15 1998, In : Experimental Cell Research. 241, 2, p. 384-393 10 p.

Research output: Contribution to journalArticle

Modulation of apoptosis in human lymphocytes by adenosine analogues

Barbieri, D., Franceschi, C., Camaioni, E., Costanzi, S., Vittori, S., Volpini, R. & Cristalli, G., Sep 22 1998, In : Bioorganic and Medicinal Chemistry Letters. 8, 18, p. 2533-2538 6 p.

Research output: Contribution to journalArticle

Neutral endopeptidase-24.11 (NEP) activity in human fibroblasts during development and ageing

Kletsas, D., Caselgrandi, E., Barbieri, D., Stathakos, D., Franceschi, C. & Ottaviani, E., May 1 1998, In : Mechanisms of Ageing and Development. 102, 1, p. 15-23 9 p.

Research output: Contribution to journalArticle

Polyamine depletion protects HL-60 cells from 2-deoxy-D-ribose-induced apoptosis

Monti, M. G., Ghiaroni, S., Pernecco, L., Barbieri, D., Marverti, G. & Franceschi, C., Jan 23 1998, In : Life Sciences. 62, 9, p. 799-806 8 p.

Research output: Contribution to journalArticle

Stable state analysis of an immune network model

Castellani, G. C., Giberti, C., Franceschi, C. & Bersani, F., Jun 1998, In : International Journal of Bifurcation and Chaos. 8, 6, p. 1285-1301 17 p.

Research output: Contribution to journalArticle

The genetics of successful aging

De Benedictis, G. & Franceschi, C., 1998, In : Aging clinical and experimental research. 10, 2, p. 147 1 p.

Research output: Contribution to journalArticle

The highly reducing sugar 2-deoxy-D-ribose induces apoptosis in human fibroblasts by reduced glutathione depletion and cytoskeletal disruption

Kletsas, D., Barbieri, D., Stathakos, D., Botti, B., Bergamini, S., Tomasi, A., Monti, D., Malorni, W. & Franceschi, C., Feb 13 1998, In : Biochemical and Biophysical Research Communications. 243, 2, p. 416-425 10 p.

Research output: Contribution to journalArticle

Thyroid autoimmunity and aging

Mariotti, S., Chiovato, L., Franceschi, C. & Pinchera, A., Sep 1998, In : Experimental Gerontology. 33, 6, p. 535-541 7 p.

Research output: Contribution to journalArticle

1999

2-deoxy-D-ribose-induced apoptosis in HL-60 cells is associated with the cell cycle progression by spermidine

Giuseppina Monti, M., Ghiaroni, S., Barbieri, D., Franceschi, C., Marverti, G. & Moruzzi, M. S., Apr 13 1999, In : Biochemical and Biophysical Research Communications. 257, 2, p. 460-465 6 p.

Research output: Contribution to journalArticle

Age-related changes of thyroid function in both sexes

Ognibene, A., Petruzzi, E., Troiano, L., Pini, G., Franceschi, C., Monti, D., Masotti, G., Messeri, G., Cilotti, A. & Forti, G., 1999, In : Journal of Endocrinological Investigation. 22, 10 SUPPL. 1, p. 38-39 2 p.

Research output: Contribution to journalArticle

AKEntAnnos. The Sardinia study of extreme longevity

Deiana, L., Ferrucci, L., Pes, G. M., Carru, C., Delitala, G., Ganau, A., Mariotti, S., Nieddu, A., Pettinato, S., Putzu, P., Franceschi, C. & Baggio, G., Jun 1999, In : Aging clinical and experimental research. 11, 3, p. 142-149 8 p.

Research output: Contribution to journalArticle

Apoptotic features of peripheral blood granulocytes and monocytes during primary, acute HIV infection

Cossarizza, A., Mussini, C., Borghi, V., Mongiardo, N., Nuzzo, C., Pedrazzi, J., Benatti, F., Moretti, L., Pinti, M., Paganelli, R., Franceschi, C. & De Rienzo, B., Feb 25 1999, In : Experimental Cell Research. 247, 1, p. 304-311 8 p.

Research output: Contribution to journalArticle

Biomarkers of immunosenescence within an evolutionary perspective: The challenge of heterogeneity and the role of antigenic load

Franceschi, C., Valensin, S., Fagnoni, F., Barbi, C. & Bonafè, M., Dec 1999, In : Experimental Gerontology. 34, 8, p. 911-921 11 p.

Research output: Contribution to journalArticle

C3-Fullero-tris-methanodicarboxylic acid protects epithelial cells from radiation-induced anoikia by influencing cell adhesion ability

Straface, E., Natalini, B., Monti, D., Franceschi, C., Schettini, G., Bisaglia, M., Fumelli, C., Pincelli, C., Pellicciari, R. & Malorni, W., Jul 9 1999, In : FEBS Letters. 454, 3, p. 335-340 6 p.

Research output: Contribution to journalArticle

C4, BF, C3 allele distribution and complement activity in healthy aged people and centenarians

Bellavia, D., Fradà, G., Di Franco, P., Feo, S., Franceschi, C., Sansoni, P. & Brai, M., Apr 1999, In : Journals of Gerontology - Series A Biological Sciences and Medical Sciences. 54, 4

Research output: Contribution to journalArticle

Cell adhesion and the immune system: A case study using earthworms

Cooper, E. L., Cossarizza, A., Kauschke, E. & Franceschi, C., Feb 15 1999, In : Microscopy Research and Technique. 44, 4, p. 237-253 17 p.

Research output: Contribution to journalArticle

Evaluation of adrenal function in aging

Troiano, L., Pini, G., Petruzzi, E., Ognibene, A., Franceschi, C., Monti, D., Masotti, G., Cilotti, A. & Forti, G., 1999, In : Journal of Endocrinological Investigation. 22, 10 SUPPL. 1, p. 74-75 2 p.

Research output: Contribution to journalArticle

Genes, demography, and life span: The contribution of demographic data in genetic studies on aging and longevity

Yashin, A. I., De Benedictis, G., Vaupel, J. W., Tan, Q., Andreev, K. F., Iachine, I. A., Bonafe, M., DeLuca, M., Valensin, S., Carotenuto, L. & Franceschi, C., 1999, In : American Journal of Human Genetics. 65, 4, p. 1178-1193 16 p.

Research output: Contribution to journalArticle

In vitro peroxidase oxidation induces stable dimers of β-amyloid (1- 42) through dityrosine bridge formation

Galeazzi, L., Ronchi, P., Franceschi, C. & Giunta, S., 1999, In : Amyloid. 6, 1, p. 7-13 7 p.

Research output: Contribution to journalArticle

Long telomeres and well preserved proliferative vigor in cells from centenarians: A contribution to longevity?

Franceschi, C., Mondello, C., Bonafè, M., Valensin, S., Sansoni, P. & Sorbi, S., Apr 1999, In : Aging clinical and experimental research. 11, 2, p. 69-72 4 p.

Research output: Contribution to journalArticle

Long-term immunologic effects of thymectomy in patients with myasthenia gravis

Gerli, R., Paganelli, R., Cossarizza, A., Muscat, C., Piccolo, G., Barbieri, D., Mariotti, S., Monti, D., Bistoni, O., Raiola, E., Venanzi, F. M., Bertotto, A. & Franceschi, C., 1999, In : Journal of Allergy and Clinical Immunology. 103, 5 I, p. 865-872 8 p.

Research output: Contribution to journalArticle

Micronucleus frequency and cell proliferation in human lymphocytes exposed to 50 Hz sinusoidal magnetic fields

Scarfi, M. R., Lioi, M. B., Zeni, O., Della Noce, M., Franceschi, C. & Bersani, F., 1999, In : Health Physics. 76, 3, p. 244-250 7 p.

Research output: Contribution to journalArticle

Mitochondrial DNA inherited variants are associated with successful aging and longevity in humans

De Benedictis, G., Rose, G., Carrieri, G., De Luca, M., Falcone, E., Passarino, G., Bonafé, M., Monti, D., Baggio, G., Bertolini, S., Mari, D., Mattace, R. & Franceschi, C., 1999, In : FASEB Journal. 13, 12, p. 1532-1536 5 p.

Research output: Contribution to journalArticle

Occurrence and expansion of trisomy 7 in a fibroblast strain from a centenarian individual

Mondello, C., Moralli, D., Franceschi, C. & Nuzzo, F., Aug 1999, In : Experimental Gerontology. 34, 5, p. 715-719 5 p.

Research output: Contribution to journalArticle

p53 Codon 72 polymorphism and longevity: Additional data on centenarians from continental Italy and Sardinia [4]

Bonafe, M., Olivieri, F., Mari, D., Baggio, G., Mattace, R., Berardelli, M., Sansoni, P., De Benedictis, G., De Luca, M., Marchegiani, F., Cavallone, L., Cardelli, M., Giovagnetti, S., Ferrucci, L., Amadio, L., Lisa, R., Tucci, M. G., Troiano, L., Pini, G., Gueresi, P. & 10 others, Morellini, M., Sorbi, S., Passeri, G., Barbi, C., Valensin, S., Monti, D., Deiana, L., Pes, G. M., Carru, C. & Franceschi, C., 1999, In : American Journal of Human Genetics. 65, 6, p. 1782-1785 4 p.

Research output: Contribution to journalArticle

p53 variants predisposing to cancer are present in healthy centenarians [2]

Bonafe, M., Olivieri, F., Mari, D., Baggio, G., Mattace, R., Sansoni, P., De Benedictis, G., De Luca, M., Bertolini, S., Barbi, C., Monti, D. & Franceschi, C., 1999, In : American Journal of Human Genetics. 64, 1, p. 292-295 4 p.

Research output: Contribution to journalArticle

Prothrombin gene mutation (G20210A) in healthy centenarians [3]

Sacchi, E., Duca, F., Franceschi, C. & Mari, D., 1999, In : Thrombosis and Haemostasis. 81, 6, p. 990-991 2 p.

Research output: Contribution to journalArticle

Resistance to apoptosis in CTLL-2 cells overexpressing B-Myb is associated with B-Myb-dependent bcl-2 induction

Grassilli, E., Salomoni, P., Perrotti, D., Franceschi, C. & Calabretta, B., May 15 1999, In : Cancer Research. 59, 10, p. 2451-2456 6 p.

Research output: Contribution to journalArticle

Serum dehydroepiandrosterone sulfate (DHEA-S) and total antioxidant capacity (TAC) in healthy centenarian subjects

Petruzzi, E., Orlando, C., Pinzani, P., Gallai, R., Ognibene, A., Grassi, E., Sorbi, S., Monti, D., Franceschi, C., Masotti, G. & Pazzagli, M., 1999, In : Journal of Endocrinological Investigation. 22, 10 SUPPL. 1, p. 76 1 p.

Research output: Contribution to journalArticle

Serum dehydroepiandrosterone sulfate (DHEA-S) and total antioxidant capacity (TAC) in healthy centenarian subjects.

Petruzzi, E., Orlando, C., Pinzani, P., Gallai, R., Ognibene, A., Grassi, E., Sorbi, S., Monti, D., Franceschi, C., Masotti, G. & Pazzagli, M., 1999, In : Journal of Endocrinological Investigation. 22, 10 Suppl, p. 76 1 p.

Research output: Contribution to journalArticle

Telomere length in fibroblasts and blood cells from healthy centenarians

Mondello, C., Petropoulou, C., Monti, D., Gonos, E. S., Franceschi, C. & Nuzzo, F., Apr 10 1999, In : Experimental Cell Research. 248, 1, p. 234-242 9 p.

Research output: Contribution to journalArticle

Testosterone, gonadotropins, prolactin and sex hormone-binding globulin in healthy centenarians

Ognibene, A., Petruzzi, E., Troiano, L., Pini, G., Franceschi, C., Monti, D., Masotti, G., Messeri, G., Cilotti, A. & Forti, G., 1999, In : Journal of Endocrinological Investigation. 22, 10 SUPPL. 1, p. 64-65 2 p.

Research output: Contribution to journalArticle

2000

Activation of the A3 adenosine receptor affects cell cycle progression and cell growth

Brambilla, R., Cattabeni, F., Ceruti, S., Barbieri, D., Franceschi, C., Kim, Y. C., Jacobson, K. A., Klotz, K. N., Lohse, M. J. & Abbracchio, M. P., 2000, In : Naunyn-Schmiedeberg's Archives of Pharmacology. 361, 3, p. 225-234 10 p.

Research output: Contribution to journalArticle