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2003

Interleukin-10 promoter polymorphism in sporadic Alzheimer's disease

Lio, D., Licastro, F., Scola, L., Chiappelli, M., Grimaldi, L. M., Crivello, A., Colonna-Romano, G., Candore, G., Franceschi, C. & Caruso, C., Apr 2003, In : Genes and Immunity. 4, 3, p. 234-238 5 p.

Research output: Contribution to journalArticle

Interleukin-6 gene alleles affect the risk of Alzheimer's disease and levels of the cytokine in blood and brain

Licastro, F., Grimaldi, L. M. E., Bonafè, M., Martina, C., Olivieri, F., Cavallone, L., Giovanietti, S., Masliah, E. & Franceschi, C., Nov 2003, In : Neurobiology of Aging. 24, 7, p. 921-926 6 p.

Research output: Contribution to journalArticle

In vitro IL-6 production by EBV-immortalized B lymphocytes from young and elderly people genotyped for -174 C/G polymorphism in IL-6 gene: A model to study the genetic basis of inflamm-aging

Olivieri, F., Bonafè, M., Giovagnetti, S., Stecconi, R., Cardelli, M., Cavallone, L., Spazzafumo, L., Marchegiani, F., Carrieri, G., Mugianesi, E., Giampieri, C., Centurelli, M., Moresi, R., Tesei, S., Lisa, R., Viticchi, C., Falsetti, L., Salvioli, S. & Franceschi, C., Apr 1 2003, In : Mechanisms of Ageing and Development. 124, 4, p. 549-553 5 p.

Research output: Contribution to journalArticle

Is chronic inflammation a determinant of blood pressure in the elderly?

Barbieri, M., Ferrucci, L., Corsi, A. M., Macchi, C., Lauretani, F., Bonafè, M., Olivieri, F., Giovagnetti, S., Franceschi, C. & Paolisso, G., Jul 1 2003, In : American Journal of Hypertension. 16, 7, p. 537-543 7 p.

Research output: Contribution to journalArticle

Karyotype instability and anchorage-independent growth in telomerase-immortalized fibroblasts from two centenarian individuals

Mondello, C., Chiesa, M., Rebuzzini, P., Zongaro, S., Verri, A., Colombo, T., Giulotto, E., D'Incalci, M., Franceschi, C. & Nuzzo, F., Sep 5 2003, In : Biochemical and Biophysical Research Communications. 308, 4, p. 914-921 8 p.

Research output: Contribution to journalArticle

Long-term immune-endocrine effects of bereavement: Relationships with anxiety levels and mood

Gerra, G., Monti, D., Panerai, A. E., Sacerdote, P., Anderlini, R., Avanzini, P., Zaimovic, A., Brambilla, F. & Franceschi, C., Dec 1 2003, In : Psychiatry Research. 121, 2, p. 145-158 14 p.

Research output: Contribution to journalArticle

Low Vitamin D Status, High Bone Turnover, and Bone Fractures in Centenarians

Passeri, G., Pini, G., Troiano, L., Vescovini, R., Sansoni, P., Passeri, M., Gueresi, P., Delsignore, R., Pedrazzoni, M. & Franceschi, C., Nov 2003, In : Journal of Clinical Endocrinology and Metabolism. 88, 11, p. 5109-5115 7 p.

Research output: Contribution to journalArticle

Marked increase with age of type 1 cytokines within memory and effector/cytotoxic CD8+ T cells in humans: A contribution to understand the relationship between inflammation and immunosenescence

Zanni, F., Vescovini, R., Biasini, C., Fagnoni, F., Zanlari, L., Telera, A., Di Pede, P., Passeri, G., Pedrazzoni, M., Passeri, M., Franceschi, C. & Sansoni, P., Sep 1 2003, In : Experimental Gerontology. 38, 9, p. 981-987 7 p.

Research output: Contribution to journalArticle

Memory and selectivity in evolving scale-free immune networks

Tieri, P., Valensin, S., Franceschi, C., Morandi, C. & Castellani, G. C., 2003, In : Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics). 2787, p. 93-101 9 p.

Research output: Contribution to journalArticle

Metabolic gene polymorphisms and p53 mutations in healthy centenarians and younger controls

Gaspari, L., Pedotti, P., Bonafè, M., Franceschi, C., Marinelli, D., Mari, D., Garte, S. & Taioli, E., Nov 2003, In : Biomarkers. 8, 6, p. 522-528 7 p.

Research output: Contribution to journalArticle

Metallothioneins/PARP-1/IL-6 interplay on natural killer cell activity in elderly: Parallelism with nonagenarians and old infected humans. Effect of zinc supply

Mocchegiani, E., Muzzioli, M., Giacconi, R., Cipriano, C., Gasparini, N., Franceschi, C., Gaetti, R., Cavalieri, E. & Suzuki, H., Apr 1 2003, In : Mechanisms of Ageing and Development. 124, 4, p. 459-468 10 p.

Research output: Contribution to journalArticle

Molecular variation of human HSP90alpha and HSP90beta genes in Caucasians.

Passarino, G., Cavalleri, G. L., Stecconi, R., Franceschi, C., Altomare, K., Dato, S., Greco, V., Luca Cavalli Sforza, L., Underhill, P. A. & de Benedictis, G., May 2003, In : Human Mutation. 21, 5, p. 554-555 2 p.

Research output: Contribution to journalArticle

Retention of the p53 Codon 72 Arginine Allele Is Associated with a Reduction of Disease-Free and Overall Survival in Arginine/Proline Heterozygous Breast Cancer Patients

Bonafé, M., Ceccarelli, C., Farabegoli, F., Santini, D., Taffurelli, M., Barbi, C., Marzi, E., Trapassi, C., Storci, G., Olivieri, F. & Franceschi, C., Oct 15 2003, In : Clinical Cancer Research. 9, 13, p. 4860-4864 5 p.

Research output: Contribution to journalArticle

Role of Connectivity in Immune and Neural Network Models: Memory Development and Aging

Remondini, D., Bazzani, A., Franceschi, C., Bersani, F., Verondini, E. & Castellani, G., 2003, In : Rivista di Biologia - Biology Forum. 96, 2, p. 225-239 15 p.

Research output: Contribution to journalArticle

Serum IL-1β levels in health and disease: A population-based study. 'The InCHIANTI study'

Di Iorio, A., Ferrucci, L., Sparvieri, E., Cherubini, A., Volpato, S., Corsi, A., Bonafè, M., Franceschi, C., Abate, G. & Paganelli, R., Jun 21 2003, In : Cytokine. 22, 6, p. 198-205 8 p.

Research output: Contribution to journalArticle

Strikingly higher frequency in centenarians and twins of mtDNA mutation causing remodeling of replication origin in leukocytes

Zhang, J., Asin-Cayuela, J., Fish, J., Michikawa, Y., Bonafé, M., Olivieri, F., Passarino, G., De Benedictis, G., Franceschi, C. & Attardi, G., Feb 4 2003, In : Proceedings of the National Academy of Sciences of the United States of America. 100, 3, p. 1116-1121 6 p.

Research output: Contribution to journalArticle

The allele (A) -110 in the promoter region of the HSP70-1 gene is unfavorable to longevity in women

Altomare, K., Greco, V., Bellizzi, D., Berardelli, M., Dato, S., DeRango, F., Garasto, S., Rose, G., Feraco, E., Mari, V., Passarino, G., Franceschi, C. & De Benedictis, G., 2003, In : Biogerontology. 4, 4, p. 215-220 6 p.

Research output: Contribution to journalArticle

The MALVA (MAntova LongeVA) study: An investigation on people 98 years of age and over in a province of Northern Italy

Gueresi, P., Troiano, L., Minicuci, N., Bonafé, M., Pini, G., Salvioli, G., Carani, C., Ferrucci, L., Spazzafumo, L., Olivieri, F., Cavrini, G., Valentini, D. & Franceschi, C., Oct 2003, In : Experimental Gerontology. 38, 10, p. 1189-1197 9 p.

Research output: Contribution to journalArticle

The role of IL-1 gene cluster in longevity: A study in Italian population

Cavallone, L., Bonafè, M., Olivieri, F., Cardelli, M., Marchegiani, F., Giovagnetti, S., Di Stasio, G., Giampieri, C., Mugianesi, E., Stecconi, R., Sciacca, F., Grimaldi, L. M., De Benedictis, G., Lio, D., Caruso, C. & Franceschi, C., Apr 1 2003, In : Mechanisms of Ageing and Development. 124, 4, p. 533-538 6 p.

Research output: Contribution to journalArticle

The study of APOA1, APOC3 and APOA4 variability in healthy ageing people reveals another paradox in the oldest old subjects

Garasto, S., Rose, G., Derango, F., Berardelli, M., Corsonello, A., Feraco, E., Mari, V., Maletta, R., Bruni, A., Franceschi, C., Carotenuto, L. & De Benedictis, G., Jan 2003, In : Annals of Human Genetics. 67, 1, p. 54-62 9 p.

Research output: Contribution to journalArticle

Variability of the SIRT3 gene, human silent information regulator Sir2 homologue, and survivorship in the elderly

Rose, G., Dato, S., Altomare, K., Bellizzi, D., Garasto, S., Greco, V., Passarino, G., Feraco, E., Mari, V., Barbi, C., BonaFe, M., Franceschi, C., Tan, Q., Boiko, S., Yashin, A. I. & De Benedictis, G., Oct 2003, In : Experimental Gerontology. 38, 10, p. 1065-1070 6 p.

Research output: Contribution to journalArticle

Von Willebrand factor in Italian centenarians

Coppola, R., Mari, D., Lattuada, A. & Franceschi, C., Feb 1 2003, In : Haematologica. 88, 1, p. 39-43 5 p.

Research output: Contribution to journalArticle

2004

1800 MHz radiofrequency (mobile phones, different Global System for Mobile communication modulations) does not affect apoptosis and heat shock protein 70 level in peripheral blood mononuclear cells from young and old donors

Capri, M., Scarcella, E., Bianchi, E., Fumelli, C., Mesirca, P., Agostini, C., Remondini, D., Schuderer, J., Kuster, N., Franceschi, C. & Bersani, F., Jun 2004, In : International Journal of Radiation Biology. 80, 6, p. 389-397 9 p.

Research output: Contribution to journalArticle

50 Hz sinusoidal magnetic fields do not affect human lymphocyte activation and proliferation in vitro

Capri, M., Mesirca, P., Remondini, D., Carosella, S., Pasi, S., Castellani, G., Franceschi, C. & Bersani, F., Dec 1 2004, In : Physical Biology. 1, 4, p. 211-219 9 p., 003.

Research output: Contribution to journalArticle

Aging, longevity, inflammation, and cancer

Caruso, C., Lio, D., Cavallone, L. & Franceschi, C., 2004, In : Annals of the New York Academy of Sciences. 1028, p. 1-13 13 p.

Research output: Contribution to journalArticle

A novel mitochondrial DNA-like sequence insertion polymorphism in Intron I of the FOXO1A gene

Giampieri, C., Centurelli, M., Bonafè, M., Olivieri, F., Cardelli, M., Marchegiani, F., Cavallone, L., Giovagnetti, S., Mugianesi, E., Carrieri, G., Lisa, R., Cenerelli, S., Testa, R., Boemi, M., Petropoulou, C., Gonos, E. S. & Franceschi, C., Mar 3 2004, In : Gene. 327, 2, p. 215-219 5 p.

Research output: Contribution to journalArticle

Anti-beta 2 glycoprotein I antibodies in centenarians

Meroni, P. L., Mari, D., Monti, D., Coppola, R., Capri, M., Salvioli, S., Tincani, A., Gerli, R. & Franceschi, C., Oct 2004, In : Experimental Gerontology. 39, 10, p. 1459-1465 7 p.

Research output: Contribution to journalArticle

Association between longevity and cytokine gene polymorphisms. A study in Sardinian centenarians

Pes, G. M., Lio, D., Carru, C., Deiana, L., Baggio, G., Franceschi, C., Ferrucci, L., Oliveri, F., Scola, L., Crivello, A., Candore, G., Colonna-Romano, G. & Caruso, C., Jun 2004, In : Aging clinical and experimental research. 16, 3, p. 244-248 5 p.

Research output: Contribution to journalArticle

Association of the mitochondrial DNA haplogroup J with longevity is population specific

Dato, S., Passarino, G., Rose, G., Altomare, K., Bellizzi, D., Mari, V., Feraco, E., Franceschi, C. & De Benedictis, G., Dec 2004, In : European Journal of Human Genetics. 12, 12, p. 1080-1082 3 p.

Research output: Contribution to journalArticle

Cloning of differentially expressed genes in skin fibroblasts from centenarians

Chondrogianni, N., Simoes, D. D. C. M., Franceschi, C. & Gonos, E. S., Nov 2004, In : Biogerontology. 5, 6, p. 401-409 9 p.

Research output: Contribution to journalArticle

Different contribution of EBV and CMV infections in very long-term carriers to age-related alterations of CD8+ T cells

Vescovini, R., Telera, A., Fagnoni, F. F., Biasini, C., Medici, M. C., Valcavi, P., Di Pede, P., Lucchini, G., Zanlari, L., Passeri, G., Zanni, F., Chezzi, C., Franceschi, C. & Sansoni, P., Aug 2004, In : Experimental Gerontology. 39, 8, p. 1233-1243 11 p.

Research output: Contribution to journalArticle

Diverse Effect of Inflammatory Markers on Insulin Resistance and Insulin-Resistance Syndrome in the Elderly

Abbatecola, A. M., Ferrucci, L., Grella, R., Bandinelli, S., Bonafè, M., Barbieri, M., Corsi, A. M., Lauretani, F., Franceschi, C. & Paolisso, G., Mar 2004, In : Journal of the American Geriatrics Society. 52, 3, p. 399-404 6 p.

Research output: Contribution to journalArticle

Effect of 4G/5G PAI-1 polymorphism on the response of PAI-1 activity to vitamin E supplementation in Type 2 diabetic patients

Testa, R., Bonfigli, A. R., Sirolla, C., Boemi, M., Manfrini, S., Mari, D., Testa, I., Sacchi, E. & Franceschi, C., Aug 2004, In : Diabetes, Nutrition and Metabolism - Clinical and Experimental. 17, 4, p. 217-221 5 p.

Research output: Contribution to journalArticle

Gender specific association of genetic variation in peroxisome proliferator-activated receptor (PPAR)γ-2 with longevity

Barbieri, M., Bonafè, M., Rizzo, M. R., Ragno, E., Olivieri, F., Marchegiani, F., Franceschi, C. & Paolisso, G., Jul 2004, In : Experimental Gerontology. 39, 7, p. 1095-1100 6 p.

Research output: Contribution to journalArticle

Heat shock response by EBV-immortalized B-lymphocytes from centenarians and control subjects: A model to study the relevance of stress response in longevity

Marini, M., Lapalombella, R., Canaider, S., Farina, A., Monti, D., De Vescovi, V., Morellini, M., Bellizzi, D., Dato, S., De Benedictis, G., Passarino, G., Moresi, R., Tesei, S. & Franceschi, C., Jan 2004, In : Experimental Gerontology. 39, 1, p. 83-90 8 p.

Research output: Contribution to journalArticle

Identification of a geographic area characterized by extreme longevity in the Sardinia island: The AKEA study

Poulain, M., Pes, G. M., Grasland, C., Carru, C., Ferrucci, L., Baggio, G., Franceschi, C. & Deiana, L., Sep 2004, In : Experimental Gerontology. 39, 9, p. 1423-1429 7 p.

Research output: Contribution to journalArticle

In vitro exposure of human lymphocytes to 900 MHz CW and GSM modulated radio-frequency: Studies of proliferation, apoptosis and mitochondrial membrane potential

Capri, M., Scarcella, E., Fumelli, C., Bianchi, E., Salvioli, S., Mesirca, P., Agostini, C., Antolini, A., Schiavoni, A., Castellani, G., Bersani, F. & Franceschi, C., Aug 2004, In : Radiation Research. 162, 2, p. 211-218 8 p.

Research output: Contribution to journalArticle

Long-term effects of vaccination on attentional performance

Nicoletti, R., Adolfo Porro, C., Brighetti, G., Monti, D., Pagnoni, G., Guido, M., Rubichi, S. & Franceschi, C., Sep 28 2004, In : Vaccine. 22, 29-30, p. 3877-3881 5 p.

Research output: Contribution to journalArticle

Lower platelet count in healthy centenarians correlates with dispersion of the QT interval

Gangemi, S., Basile, G., Merendino, R. A., Balbo, C. L., Mento, A., Nicita-Mauro, V., Franceschi, C. & Romano, M., Apr 2004, In : Aging clinical and experimental research. 16, 2, p. 169-171 3 p.

Research output: Contribution to journalArticle

Meeting report: Breast cancer in the older woman

Martoni, A., Cucinotta, D., Balducci, L., Aapro, M., Anisimov, V., Ausili-Cefaro, G., Bernabei, R., Caraceni, A., Costa, A., Crivellari, D., Daidone, M. G., Extermann, M., Fabris, F., Franceschi, C., Hayman, J. A., Lelli, G., Masina, A., Monfardini, S., Mustacchi, G., Piana, E. & 9 others, Repetto, L., Della Cuna, G. R., Rosti, G., Valagussa, P., Taffurelli, M., Tanneberger, S., Torta, R., Zamagni, C. & Zappa, M., Jul 2004, In : Tumori. 90, 4, p. 437-445 9 p.

Research output: Contribution to journalArticle

Opposite effects of interleukin 10 common gene polymorphisms in cardiovascular diseases and in successful ageing: Genetic background of male centenarians is protective against coronary heart disease

Lio, D., Candore, G., Crivello, A., Scola, L., Colonna-Romano, G., Cavallone, L., Hoffmann, E., Caruso, M., Licastro, F., Caldarera, C. M., Branzi, A., Franceschi, C. & Caruso, C., Oct 2004, In : Journal of Medical Genetics. 41, 10, p. 790-794 5 p.

Research output: Contribution to journalArticle

Paraoxonase polymorphisms PON1 192 and 55 and longevity in Italian centenarians and Irish nonagenarians. A pooled analysis

Rea, I. M., McKeown, P. P., McMaster, D., Young, I. S., Patterson, C., Savage, M. J., Belton, C., Marchegiani, F., Olivieri, F., Bonafe, M. & Franceschi, C., Apr 2004, In : Experimental Gerontology. 39, 4, p. 629-635 7 p.

Research output: Contribution to journalArticle

Plasminogen activator inhibitor-I plasma level increases with age in subjects with the 4G allele at position -675 in the promoter region [3]

Bonfigli, A. R., Sirolla, C., Cenerelli, S., Marra, M., Boemi, M., Franceschi, C., Testa, I., Mari, D., Sacchi, E. & Testa, R., Nov 2004, In : Thrombosis and Haemostasis. 92, 5, p. 1164-1165 2 p.

Research output: Contribution to journalArticle

Role of toll-like receptor 4 in acute myocardial infarction and longevity [4]

Balistreri, C. R., Candore, G., Colonna-Romano, G., Lio, D., Caruso, M., Hoffmann, E., Franceschi, C. & Caruso, C., Nov 17 2004, In : Journal of the American Medical Association. 292, 19, p. 2339-2340 2 p.

Research output: Contribution to journalArticle

The - 174G/C polymorphism of IL-6 is useful to screen old subjects at risk for atherosclerosis or to reach successful ageing

Giacconi, R., Cipriano, C., Albanese, F., Boccoli, G., Saba, V., Olivieri, F., Franceschi, C. & Mocchegiani, E., Apr 2004, In : Experimental Gerontology. 39, 4, p. 621-628 8 p.

Research output: Contribution to journalArticle

The different apoptotic potential of the p53 codon 72 alleles increases with age and modulates in vivo ischaemia-induced cell death

Bonafé, M., Salvioli, S., Barbi, C., Trapassi, C., Tocco, F., Storci, G., Invidia, L., Vannini, I., Rossi, M., Marzi, E., Mishto, M., Capri, M., Olivieri, F., Antonicelli, R., Memo, M., Uberti, D., Nacmias, B., Sorbi, S., Monti, D. & Franceschi, C., Sep 2004, In : Cell Death and Differentiation. 11, 9, p. 962-973 12 p.

Research output: Contribution to journalArticle

The effect on rat thymocytes of the simultaneous in vivo exposure to 50-Hz electric and magnetic field and to continuous light.

Quaglino, D., Capri, M., Zecca, L., Franceschi, C. & Ronchetti, I. P., Oct 20 2004, In : TheScientificWorldJournal. 4 Suppl 2, p. 91-99 9 p.

Research output: Contribution to journalArticle

The G/C915 polymorphism of transforming growth factor β1 is associated with human longevity: A study in Italian centenarians

Carrieri, G., Marzi, E., Olivieri, F., Marchegiani, F., Cavallone, L., Cardelli, M., Giovagnetti, S., Stecconi, R., Molendini, C., Trapassi, C., De Benedictis, G., Kletsas, D. & Franceschi, C., Dec 2004, In : Aging Cell. 3, 6, p. 443-448 6 p.

Research output: Contribution to journalArticle