1969 …2020

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Nutritional factors modulating alu methylation in an italian sample from the mark-age study including offspring of healthy nonagenarians

Giacconi, R., Malavolta, M., Bürkle, A., Moreno-Villanueva, M., Franceschi, C., Capri, M., Eline Slagboom, P., Jansen, E. H. J. M., Dollé, M. E. T., Grune, T., Weber, D., Hervonen, A., Stuetz, W., Breusing, N., Ciccarone, F., Zampieri, M., Aversano, V., Caiafa, P., Formentini, L., Piacenza, F. & 4 others, Pierpaoli, E., Basso, A., Provinciali, M. & Cardelli, M., Dec 2019, In : Nutrients. 11, 12, 2986.

Research output: Contribution to journalArticle

Open Access

Numerical and functional alterations of circulating γδ T lymphocytes in aged people and centenarians

Argentati, K., Re, F., Donnini, A., Tucci, M. G., Franceschi, C., Bartozzi, B., Bernardini, G. & Provinciali, M., Jul 1 2002, In : Journal of Leukocyte Biology. 72, 1, p. 65-71 7 p.

Research output: Contribution to journalArticle

Nucleoside transport in activated macrophages

Busolo, F., Conventi, L., Gatti, C., Monti, D., Troiano, L. & Franceschi, C., Apr 14 1989, In : Biochemical and Biophysical Research Communications. 160, 1, p. 354-361 8 p.

Research output: Contribution to journalArticle

Novel loci and pathways significantly associated with longevity

Zeng, Y., Nie, C., Min, J., Liu, X., Li, M., Chen, H., Xu, H., Wang, M., Ni, T., Li, Y., Yan, H., Zhang, J. P., Song, C., Chi, L. Q., Wang, H. M., Dong, J., Zheng, G. Y., Lin, L., Qian, F., Qi, Y. & 37 others, Liu, X., Cao, H., Wang, Y., Zhang, L., Li, Z., Zhou, Y., Wang, Y., Lu, J., Li, J., Qi, M., Bolund, L., Yashin, A., Land, K. C., Gregory, S., Yang, Z., Gottschalk, W., Tao, W., Wang, J., Wang, J., Xu, X., Bae, H., Nygaard, M., Christiansen, L., Christensen, K., Franceschi, C., Lutz, M. W., Gu, J., Tan, Q., Perls, T., Sebastiani, P., Deelen, J., Slagboom, E., Hauser, E., Xu, H., Tian, X. L., Yang, H. & Vaupel, J. W., Feb 25 2016, In : Scientific Reports. 6, 21243.

Research output: Contribution to journalArticle

NK cell activity and T-lymphocyte proliferation in healthy centenarians

Sansoni, P., Brianti, V., Fagnoni, F., Snelli, G., Marcato, A., Passeri, G., Monti, D., Cossarizza, A. & Franceschi, C., 1992, In : Annals of the New York Academy of Sciences. 663, p. 505-507 3 p.

Research output: Contribution to journalArticle

N-Glycomic changes in serum proteins in type 2 diabetes mellitus correlate with complications and with metabolic syndrome parameters

Testa, R., Vanhooren, V., Bonfigli, A. R., Boemi, M., Olivieri, F., Ceriello, A., Genovese, S., Spazzafumo, L., Borelli, V., Bacalini, M. G., Salvioli, S., Garagnani, P., Dewaele, S., Libert, C. & Franceschi, C., Mar 20 2015, In : PLoS One. 10, 3, e0119983.

Research output: Contribution to journalArticle

N-glycomic changes in serum proteins during human aging

Vanhooren, V., Desmyter, L., Liu, X. E., Cardelli, M., Franceschi, C., Federico, A., Libert, C., Laroy, W., Dewaele, S., Contreras, R. & Chen, C., Dec 1 2007, In : Rejuvenation Research. 10, 4, p. 521-531 11 p.

Research output: Contribution to journalArticle

N-glycomic biomarkers of biological aging and longevity: A link with inflammaging

Dall'Olio, F., Vanhooren, V., Chen, C. C., Slagboom, P. E., Wuhrer, M. & Franceschi, C., Mar 2013, In : Ageing Research Reviews. 12, 2, p. 685-698 14 p.

Research output: Contribution to journalArticle

N-glycan profiles as tools in diagnosis of hepatocellular carcinoma and prediction of healthy human ageing

Vanhooren, V., Liu, X. E., Franceschi, C., Gao, C. F., Libert, C., Contreras, R. & Chen, C., Jan 2009, In : Mechanisms of Ageing and Development. 130, 1-2, p. 92-97 6 p.

Research output: Contribution to journalArticle

New advances in CMV and immunosenescence

Sansoni, P., Vescovini, R., Fagnoni, F. F., Akbar, A., Arens, R., Chiu, Y. L., Čičin-Šain, L., Dechanet-Merville, J., Derhovanessian, E., Ferrando-Martinez, S., Franceschi, C., Frasca, D., Fulöp, T., Furman, D., Gkrania-Klotsas, E., Goodrum, F., Grubeck-Loebenstein, B., Hurme, M., Kern, F., Lilleri, D. & 20 others, López-Botet, M., Maier, A. B., Marandu, T., Marchant, A., Matheï, C., Moss, P., Muntasell, A., Remmerswaal, E. B. M., Riddell, N. E., Rothe, K., Sauce, D., Shin, E. C., Simanek, A. M., Smithey, M. J., Söderberg-Nauclér, C., Solana, R., Thomas, P. G., Van Lier, R., Pawelec, G. & Nikolich-Zugich, J., 2014, In : Experimental Gerontology. 55, p. 54-62 9 p.

Research output: Contribution to journalArticle

Neutral endopeptidase-24.11 (NEP) activity in human fibroblasts during development and ageing

Kletsas, D., Caselgrandi, E., Barbieri, D., Stathakos, D., Franceschi, C. & Ottaviani, E., May 1 1998, In : Mechanisms of Ageing and Development. 102, 1, p. 15-23 9 p.

Research output: Contribution to journalArticle

Neuroinflammation and the genetics of Alzheimer's disease: The search for a pro-inflammatory phenotype

Franceschi, C., Valensin, S., Lescai, F., Olivieri, F., Licastro, F., Grimaldi, L. M. E., Monti, D., De Benedictis, G. & Bonafè, M., 2001, In : Aging clinical and experimental research. 13, 3, p. 163-170 8 p.

Research output: Contribution to journalArticle

Networks from gene expression time series: Characterization of correlation patterns

Remondini, D., Neretti, N., Franceschi, C., Tieri, P., Sedivy, J. M., Milanesi, L. & Castellani, G. C., Jul 2007, In : International Journal of Bifurcation and Chaos. 17, 7, p. 2477-2483 7 p.

Research output: Contribution to journalArticle

Network, degeneracy and bow tie integrating paradigms and architectures to grasp the complexity of the immune system

Tieri, P., Grignolio, A., Zaikin, A., Mishto, M., Remondini, D., Castellani, G. C. & Franceschi, C., 2010, In : Theoretical Biology and Medical Modelling. 7, 1, 32.

Research output: Contribution to journalArticle

Natural cytotoxicity in a freshwater pulmonate mollusc: an unorthodox comparative approach

Franceschi, C., Cossarizza, A., Ortolani, C., Monti, D. & Ottaviani, E., 1991, In : Advances in Neuroimmunology. 1, 2, p. 99-113 15 p.

Research output: Contribution to journalArticle

Naïve and memory CD8 T cell pool homeostasis in advanced aging: Impact of age and of antigen-specific responses to cytomegalovirus

Vescovini, R., Fagnoni, F. F., Telera, A. R., Bucci, L., Pedrazzoni, M., Magalini, F., Stella, A., Pasin, F., Medici, M. C., Calderaro, A., Volpi, R., Monti, D., Franceschi, C., Nikolich-Žugich, J. & Sansoni, P., 2014, In : Age. 36, 2, p. 625-640 16 p.

Research output: Contribution to journalArticle

Mutant factor V (Arg506Gln) in healthy centenarians [6]

Mari, D., Mannucci, P. M., Duca, F., Bertolini, S. & Franceschi, C., 1996, In : Lancet. 347, 9007, p. 1044 1 p.

Research output: Contribution to journalArticle

Musculoskeletal system in the old age and the demand for healthy ageing biomarkers

Collino, S., Martin, F. P., Karagounis, L. G., Horcajada, M. N., Moco, S., Franceschi, C., Kussmann, M. & Offord, E., 2014, In : Mechanisms of Ageing and Development. 134, 11-12, p. 541-547 7 p.

Research output: Contribution to journalArticle

MtDNA mutations in human aging and longevity: Controversies and new perspectives opened by high-throughput technologies

Sevini, F., Giuliani, C., Vianello, D., Giampieri, E., Santoro, A., Biondi, F., Garagnani, P., Passarino, G., Luiselli, D., Capri, M., Franceschi, C. & Salvioli, S., 2014, In : Experimental Gerontology. 56, p. 234-244 11 p.

Research output: Contribution to journalArticle

Morpho-functional changes of fat body in bacteria fed Drosophila melanogaster strains

Franchini, A., Mandrioli, M., Franceschi, C. & Ottaviani, E., Apr 2012, In : Journal of Molecular Histology. 43, 2, p. 243-251 9 p.

Research output: Contribution to journalArticle

Molecular variation of human HSP90alpha and HSP90beta genes in Caucasians.

Passarino, G., Cavalleri, G. L., Stecconi, R., Franceschi, C., Altomare, K., Dato, S., Greco, V., Luca Cavalli Sforza, L., Underhill, P. A. & de Benedictis, G., May 2003, In : Human Mutation. 21, 5, p. 554-555 2 p.

Research output: Contribution to journalArticle

Molecular remodeling of potassium channels in fibroblasts from centenarians: A marker of longevity?

Zironi, I., Gaibani, P., Remondini, D., Salvioli, S., Altilia, S., Pierini, M., Aicardi, G., Verondini, E., Milanesi, L., Bersani, F., Gravina, S., Roninson, I. B., Franceschi, C. & Castellani, G., Nov 2010, In : Mechanisms of Ageing and Development. 131, 11-12, p. 674-681 8 p.

Research output: Contribution to journalArticle

Molecular aging of human liver: An epigenetic/transcriptomic signature

Bacalini, M. G., Franceschi, C., Gentilini, D., Ravaioli, F., Zhou, X., Remondini, D., Pirazzini, C., Giuliani, C., Marasco, E., Gensous, N., Di Blasio, A. M., Ellis, E., Gramignoli, R., Castellani, G., Capri, M., Strom, S., Nardini, C., Cescon, M., Grazi, G. L. & Garagnani, P., 2019, In : Journals of Gerontology - Series A Biological Sciences and Medical Sciences. 74, 1, p. 1-8 8 p.

Research output: Contribution to journalArticle

Modulation of apoptosis in human lymphocytes by adenosine analogues

Barbieri, D., Franceschi, C., Camaioni, E., Costanzi, S., Vittori, S., Volpini, R. & Cristalli, G., Sep 22 1998, In : Bioorganic and Medicinal Chemistry Letters. 8, 18, p. 2533-2538 6 p.

Research output: Contribution to journalArticle

Modulation of apoptosis by adenosine in the central nervous system: A possible role for the A3 receptor. Pathophysiological significance and therapeutic implications for neurodegenerative disorders

Abbracchio, M. P., Ceruti, S., Brambilla, R., Franceschi, C., Malorni, W., Jacobson, K. A., Von Lubitz, D. K. J. E. & Cattabeni, F., 1997, In : Annals of the New York Academy of Sciences. 825, p. 11-22 12 p.

Research output: Contribution to journalArticle

Modeling the in Vitro 20S Proteasome Activity: The Effect of PA28-αβ and of the Sequence and Length of Polypeptides on the Degradation Kinetics

Mishto, M., Luciani, F., Holzhütter, H. G., Bellavista, E., Santoro, A., Textoris-Taube, K., Franceschi, C., Kloetzel, P. M. & Zaikin, A., Apr 11 2008, In : Journal of Molecular Biology. 377, 5, p. 1607-1617 11 p.

Research output: Contribution to journalArticle

Mitogenic and haemagglutinating properties of a lectinpurified from Hura crepitans seeds.

Falasca, A., Franceschi, C., Rossi, C. A. & Stirpe, F., Sep 17 1980, In : BBA - General Subjects. 632, 1, p. 95-105 11 p.

Research output: Contribution to journalArticle

Mitochondrial modifications during rat thymocyte apoptosis: A study at the single cell level

Cossarizza, A., Kalashnikova, G., Grassilli, E., Chiappelli, F., Salvioli, S., Capri, M., Barbieri, D., Troiano, L., Monti, D. & Franceschi, C., 1994, In : Experimental Cell Research. 214, 1, p. 323-330 8 p.

Research output: Contribution to journalArticle

Mitochondrial membrane potential and DNA stainability in human sperm cells: A flow cytometry analysis with implications for male infertility

Troiano, L., Granata, A. R. M., Cossarizza, A., Kalashnikova, G., Bianchi, R., Pini, G., Tropea, F., Carani, C. & Franceschi, C., Jun 15 1998, In : Experimental Cell Research. 241, 2, p. 384-393 10 p.

Research output: Contribution to journalArticle

Mitochondrial Mass and Membrane Potential in Celomocytes from the Earthworm Eisenia foetida: Studies with Fluorescent Probes in Single Intact Cells

Cossarizza, A., Cooper, E. L., Quaglino, D., Salvioli, S., Kalachnikova, G. & Franceschi, C., Sep 14 1995, In : Biochemical and Biophysical Research Communications. 214, 2, p. 503-510 8 p.

Research output: Contribution to journalArticle

Mitochondrial heterogeneity during staurosporine-induced apoptosis in HL60 cells: Analysis at the single cell and single organelle level

Salvioli, S., Dobrucki, J., Moretti, L., Troiano, L., Fernandez, M. G., Pinti, M., Pedrazzi, J., Franceschi, C. & Cossarizza, A., 2000, In : Cytometry. 40, 3, p. 189-197 9 p.

Research output: Contribution to journalArticle

Mitochondrial DNA involvement in human longevity

Santoro, A., Salvioli, S., Raule, N., Capri, M., Sevini, F., Valensin, S., Monti, D., Bellizzi, D., Passarino, G., Rose, G., De Benedictis, G. & Franceschi, C., Sep 2006, In : Biochimica et Biophysica Acta - Bioenergetics. 1757, 9-10, p. 1388-1399 12 p.

Research output: Contribution to journalArticle

Mitochondrial DNA inherited variants are associated with successful aging and longevity in humans

De Benedictis, G., Rose, G., Carrieri, G., De Luca, M., Falcone, E., Passarino, G., Bonafé, M., Monti, D., Baggio, G., Bertolini, S., Mari, D., Mattace, R. & Franceschi, C., 1999, In : FASEB Journal. 13, 12, p. 1532-1536 5 p.

Research output: Contribution to journalArticle

Mitochondrial DNA haplogroups and APOE4 allele are non-independent variables in sporadic Alzheimer's disease

Carrieri, G., Bonafè, M., De Luca, M., Rose, G., Varcasia, O., Bruni, A., Maletta, R., Nacmias, B., Sorbi, S., Corsonello, F., Feraco, E., Andreev, K. F., Yashin, A. I., Franceschi, C. & De Benedictis, G., 2001, In : Human Genetics. 108, 3, p. 194-198 5 p.

Research output: Contribution to journalArticle

Mitochondrial DNA backgrounds might modulate diabetes complications rather than T2DM as a whole

Achilli, A., Olivieri, A., Pala, M., Kashani, B. H., Carossa, V., Perego, U. A., Gandini, F., Santoro, A., Battaglia, V., Grugni, V., Lancioni, H., Sirolla, C., Bonfigli, A. R., Cormio, A., Boemi, M., Testa, I., Semino, O., Ceriello, A., Spazzafumo, L., Gadaleta, M. N. & 4 others, Marra, M., Testa, R., Franceschi, C. & Torroni, A., 2011, In : PLoS One. 6, 6, e21029.

Research output: Contribution to journalArticle

Mitochondria hyperfusion and elevated autophagic activity are key mechanisms for cellular bioenergetic preservation in centenarians

Sgarbi, G., Matarrese, P., Pinti, M., Lanzarini, C., Ascione, B., Gibellini, L., Dika, E., Patrizi, A., Tommasino, C., Capri, M., Cossarizza, A., Baracca, A., Lenaz, G., Solaini, G., Franceschi, C., Malorni, W. & Salvioli, S., 2014, In : Aging. 6, 4, p. 296-310 15 p.

Research output: Contribution to journalArticle

Mitochondria are selective targets for the protective effects of heat shock against oxidative injury

Polla, B. S., Kantengwa, S., François, D., Salvioli, S., Franceschi, C., Marsac, C. & Cossarizza, A., Jun 25 1996, In : Proceedings of the National Academy of Sciences of the United States of America. 93, 13, p. 6458-6463 6 p.

Research output: Contribution to journalArticle

Mitochondria alterations and dramatic tendency to undergo apoptosis in peripheral blood lymphocytes during acute HIV syndrome

Cossarizza, A., Mussini, C., Mongiardo, N., Borghi, V., Sabbatini, A., De Rienzo, B. & Franceschi, C., 1997, In : AIDS (London, England). 11, 1, p. 19-26 8 p.

Research output: Contribution to journalArticle

Mitochondria, aging and longevity - A new perspective

Salvioli, S., Bonafè, M., Capri, M., Monti, D. & Franceschi, C., Mar 9 2001, In : FEBS Letters. 492, 1-2, p. 9-13 5 p.

Research output: Contribution to journalArticle

miRNAs expression analysis in paired fresh/Frozen and dissected formalin fixed and paraffin embedded glioblastoma using real-time PCR

de Biase, D., Visani, M., Morandi, L., Marucci, G., Taccioli, C., Cerasoli, S., Baruzzi, A., Pession, A., Baruzzi, A., Albani, F., Calbucci, F., D'Alessandro, R., Michelucci, R., Brandes, A., Eusebi, V., Ceruti, S., Fainardi, E., Tamarozzi, R., Emiliani, E., Cavallo, M. & 125 others, Franceschi, E., Tosoni, A., Cavallo, M., Fiorica, F., Valentini, A., Depenni, R., Mucciarini, C., Crisi, G., Sasso, E., Biasini, C., Cavanna, L., Guidetti, D., Marcello, N., Pisanello, A., Cremonini, A. M., Guiducci, G., de Pasqua, S., Testoni, S., Agati, R., Ambrosetto, G., Bacci, A., Baldin, E., Baldrati, A., Barbieri, E., Bartolini, S., Bellavista, E., Bisulli, F., Bonora, E., Bunkheila, F., Carelli, V., Crisci, M., Dall'Occa, P., Ferro, S., Franceschi, C., Frezza, G., Grasso, V., Leonardi, M., Mostacci, B., Palandri, G., Pasini, E., Pastore Trossello, M., Poggi, R., Riguzzi, P., Rinaldi, R., Rizzi, S., Romeo, G., Spagnolli, F., Tinuper, P., Trocino, C., Dall'Agata, M., Faedi, M., Frattarelli, M., Gentili, G., Giovannini, A., Iorio, P., Pasquini, U., Galletti, G., Guidi, C., Neri, W., Patuelli, A., Strumia, S., Casmiro, M., Gamboni, A., Rasi, F., Cruciani, G., Cenni, P., DazziDazzi, C., Guidi, A. R., Zumaglini, F., Amadori, A., Pasini, G., Pasquinelli, M., Pasquini, E., Polselli, A., Ravasio, A., Viti, B., Sintini, M., Ariatti, A., Bertolini, F., Bigliardi, G., Carpeggiani, P., Cavalleri, F., Meletti, S., Nichelli, P., Pettorelli, E., Pinna, G., Zunarelli, E., Artioli, F., Bernardini, I., Costa, M., Greco, G., Guerzoni, R., Stucchi, C., Iaccarino, C., Ragazzi, M., Rizzi, R., Zuccoli, G., Api, P., Cartei, F., Fallica, E., Granieri, E., Latini, F., Lelli, G., Monetti, C., Saletti, A., Schivalocchi, R., Seraceni, S., Tola, M. R., Urbini, B., Giorgi, C., Montanari, E., Cerasti, D., Crafa, P., Dascola, I., Florindo, I., Giombelli, E., Mazza, S., Ramponi, V., Servadei, F., Silini, E. M., Torelli, P., Immovilli, P., Morelli, N., Vanzo, C. & Nobile, C., Apr 18 2012, In : PLoS One. 7, 4, e35596.

Research output: Contribution to journalArticle

MiR-146a as marker of senescence-Associated pro-inflammatory status in cells involved in vascular remodelling

Olivieri, F., Lazzarini, R., Recchioni, R., Marcheselli, F., Rippo, M. R., Di Nuzzo, S., Albertini, M. C., Graciotti, L., Babini, L., Mariotti, S., Spada, G., Abbatecola, A. M., Antonicelli, R., Franceschi, C. & Procopio, A. D., Aug 2013, In : Age. 35, 4, p. 1157-1172 16 p.

Research output: Contribution to journalArticle

MicroRNAs linking inflamm-aging, cellular senescence and cancer

Olivieri, F., Rippo, M. R., Monsurrò, V., Salvioli, S., Capri, M., Procopio, A. D. & Franceschi, C., Sep 2013, In : Ageing Research Reviews. 12, 4, p. 1056-1068 13 p.

Research output: Contribution to journalArticle

Microplate enzyme-linked immunosorbent assay in the study of the structural relationship between myosin light chains

Biral, D., Libera, L. D., Franceschi, C. & Margreth, A., Dec 14 1979, In : Journal of Immunological Methods. 31, 1-2, p. 93-100 8 p.

Research output: Contribution to journalArticle

Micronucleus frequency and cell proliferation in human lymphocytes exposed to 50 Hz sinusoidal magnetic fields

Scarfi, M. R., Lioi, M. B., Zeni, O., Della Noce, M., Franceschi, C. & Bersani, F., 1999, In : Health Physics. 76, 3, p. 244-250 7 p.

Research output: Contribution to journalArticle

Methylation of ELOVL2 gene as a new epigenetic marker of age

Garagnani, P., Bacalini, M. G., Pirazzini, C., Gori, D., Giuliani, C., Mari, D., Di Blasio, A. M., Gentilini, D., Vitale, G., Collino, S., Rezzi, S., Castellani, G., Capri, M., Salvioli, S. & Franceschi, C., Dec 2012, In : Aging Cell. 11, 6, p. 1132-1134 3 p.

Research output: Contribution to journalArticle

Metformin improves putative longevity effectors in peripheral mononuclear cells from subjects with prediabetes. A randomized controlled trial

Vigili de Kreutzenberg, S., Ceolotto, G., Cattelan, A., Pagnin, E., Mazzucato, M., Garagnani, P., Borelli, V., Bacalini, M. G., Franceschi, C., Fadini, G. P. & Avogaro, A., Jul 1 2015, In : Nutrition, Metabolism and Cardiovascular Diseases. 25, 7, p. 686-693 8 p.

Research output: Contribution to journalArticle

Metallothioneins/PARP-1/IL-6 interplay on natural killer cell activity in elderly: Parallelism with nonagenarians and old infected humans. Effect of zinc supply

Mocchegiani, E., Muzzioli, M., Giacconi, R., Cipriano, C., Gasparini, N., Franceschi, C., Gaetti, R., Cavalieri, E. & Suzuki, H., Apr 1 2003, In : Mechanisms of Ageing and Development. 124, 4, p. 459-468 10 p.

Research output: Contribution to journalArticle

Metabolic syndrome in the offspring of centenarians: Focus on prevalence, components, and adipokines

Ostan, R., Bucci, L., Cevenini, E., Palmas, M. G., Pini, E., Scurti, M., Vescovini, R., Caruso, C., Mari, D., Vitale, G., Franceschi, C. & Monti, D., Oct 2013, In : Age. 35, 5, p. 1995-2007 13 p.

Research output: Contribution to journalArticle

Metabolic Signatures of Extreme Longevity in Northern Italian Centenarians Reveal a Complex Remodeling of Lipids, Amino Acids, and Gut Microbiota Metabolism

Collino, S., Montoliu, I., Martin, F. P. J., Scherer, M., Mari, D., Salvioli, S., Bucci, L., Ostan, R., Monti, D., Biagi, E., Brigidi, P., Franceschi, C. & Rezzi, S., Mar 6 2013, In : PLoS One. 8, 3, e56564.

Research output: Contribution to journalArticle