1969 …2020

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Precocious aging of the immune system in Down syndrome: Alteration of B lymphocytes, T-lymphocyte subsets, and cells with natural killer markers

Cossarizza, A., Monti, D., Montagnani, G., Ortolani, C., Masi, M., Zannotti, M. & Franceschi, C., 1990, In : American Journal of Medical Genetics. SUPPL. 7, p. 213-218 6 p.

Research output: Contribution to journalArticle

Preface

Fulop, T., Franceschi, C., Hirokawa, K. & Pawelec, G., 2009, In : Unknown Journal. p. v-vi

Research output: Contribution to journalArticle

Preface

Santoro, A., Brigidi, P., Gonos, E. S., Bohr, V. A. & Franceschi, C., 2014, In : Mechanisms of Ageing and Development. 136-137, p. 1-2 2 p.

Research output: Contribution to journalArticle

Preferential expression of Vβ6.7 domain on human peripheral CD4+ T cells. Implication for positive selection of T cells in man

Cossarizza, A., Kahan, M., Ortolani, C., Franceschi, C. & Londei, M., Jun 1991, In : European Journal of Immunology. 21, 6, p. 1571-1574 4 p.

Research output: Contribution to journalArticle

Preoperative, high IL-6 blood level is a risk factor of postoperative delirium onset in old patients

Capri, M., Lukas-Yani, S., Chattat, R., Fortuna, D., Bucci, L., Lanzarini, C., Morsiani, C., Catena, F., Ansaloni, L., Adversi, M., Melotti, M. R., Di Nino, G. & Franceschi, C., 2014, In : Frontiers in Endocrinology. 5, SEP, 173.

Research output: Contribution to journalArticle

Presence and role of cytokines and growth factors in invertebrates

Ottaviani, E., Franchini, A., Kletsas, D. & Franceschi, C., 1996, In : Italian Journal of Zoology. 63, 4, p. 317-323 7 p.

Research output: Contribution to journalArticle

Presence of ACTH and β-endorphin immunoreactive molecules in the freshwater snail Planorbarius corneus (L.) (Gastropoda, Pulmonata) and their possible role in phagocytosis

Ottaviani, E., Petraglia, F., Montagnani, G., Cossarizza, A., Monti, D. & Franceschi, C., Jan 1 1990, In : Regulatory Peptides. 27, 1, p. 1-9 9 p.

Research output: Contribution to journalArticle

Presence of a functional vitamin D receptor does not correlate with vitamin D3 phenotypic effects in myeloid differentiation

Grande, A., Manfredini, R., Pizzanelli, M., Tagliafico, E., Balestri, R., Trevisan, F., Barbieri, D., Franceschi, C., Battini, R., Ferrari, S. & Ferrari, S., 1997, In : Cell Death and Differentiation. 4, 6, p. 497-505 9 p.

Research output: Contribution to journalArticle

Presence of immunoreactive pro-opiomelanocortin-derived peptides and cytokines in the thymus of an anuran amphibian (Rana esculenta)

Franchini, A., Ottaviani, E. & Franceschi, C., 1995, In : Tissue and Cell. 27, 3, p. 263-267 5 p.

Research output: Contribution to journalArticle

Presence of Several Cytokine-like Molecules in Molluscan Hemocytes

Ottaviani, E., Franchini, A. & Franceschi, C., Sep 15 1993, In : Biochemical and Biophysical Research Communications. 195, 2, p. 984-988 5 p.

Research output: Contribution to journalArticle

Present and future of anti-ageing epigenetic diets

Bacalini, M. G., Friso, S., Olivieri, F., Pirazzini, C., Giuliani, C., Capri, M., Santoro, A., Franceschi, C. & Garagnani, P., 2014, In : Mechanisms of Ageing and Development. 136-137, p. 101-115 15 p.

Research output: Contribution to journalArticle

Prevalence and loads of torquetenovirus (TTV) in the European MARK-AGE Study population

Giacconi, R., Maggi, F., Macera, L., Spezia, P. G., Pistello, M., Provinciali, M., Piacenza, F., Basso, A., Bürkle, A., Moreno-Villanueva, M., Dollé, M. E. T., Jansen, E., Grune, T., Stuetz, W., Gonos, E. S., Schön, C., Bernhardt, J., Grubeck-Loebenstein, B., Sikora, E., Dudkowska, M. & 11 others, Janiszewska, D., Toussaint, O., Chainiaux, F. D., Franceschi, C., Capri, M., Hervonen, A., Hurme, M., Slagboom, E., Breusing, N., Mocchegiani, E. & Malavolta, M., Dec 15 2019, In : The journals of gerontology. Series A, Biological sciences and medical sciences.

Research output: Contribution to journalArticle

Production of antibodies to amanitins as the basis for their radioimmunoassay

Fiume, L., Busi, C., Campadelli-Fiume, G. & Franceschi, C., 1975, In : Experientia. 31, 10, p. 1233-1234 2 p.

Research output: Contribution to journalArticle

Prolactin increases the susceptibility of primary leukemia cells to NK and LAK effectors

Oberholtzer, E., Contarini, M., Veglia, F., Cossarizza, A., Franceschi, C., Geuna, M., Provinciali, M., Di Stefano, G., Sissom, J., Brizzi, M. F., Pegoraro, L. & Matera, L., 1996, In : Advances in Neuroimmunology. 6, 3, p. 233-247 15 p.

Research output: Contribution to journalArticle

Pro-opiomelanocortin-derived peptides, cytokines, and nitric oxide in immune responses and stress: An evolutionary approach

Ottaviani, E., Franchini, A. & Franceschi, C., 1997, In : International Review of Cytology. 170, p. 79-141 63 p.

Research output: Contribution to journalArticle

Propagation of a transmissible cytotoxic activity on cultures of human peripheral blood lymphocytes

Portolani, M., Beretti, F., Bartoletti, A. M., Pietrosemoli, P., Salvioli, S., Franceschi, C., Sena, P. & De Pol, A., Jul 2008, In : New Microbiologica. 31, 3, p. 417-422 6 p.

Research output: Contribution to journalArticle

Properties of a glycopeptide isolated from human Tamm-Horsfall glycoprotein. Interaction with leucoagglutinin and anti-(human Tamm-Horsfall glycoprotein) antibodies

Abbondanza, A., Franceschi, C., Licastro, F. & Serafini-Cessi, F., 1980, In : Biochemical Journal. 187, 2, p. 525-528)

Research output: Contribution to journalArticle

Prostaglandin and thromboxane biosynthesis in resting and activated platelet-free monocytes from aged subjects

Chiricolo, M., Bartolini, G., Orlandi, M., Peta, G., Corneli, M., Spinosa, M., Tomasi, V. & Franceschi, C., 1986, In : Gerontology. 32, 2, p. 69-73 5 p.

Research output: Contribution to journalArticle

Prostaglandins and cyclic nucleotides as effectors in non-lymphocyte mediated surveillance processes ( short review).

Mastacchi, R., Bartolini, G., Orlandi, M., Chiricolo, M., Guerrini, F., Franceschi, C. & Tomasi, V., Mar 1985, In : Anticancer Research. 5, 2, p. 167-170 4 p.

Research output: Contribution to journalArticle

Prostanoids as second messengers of polypeptide growth factors

Franceschi, C., Bartolini, G., Orlandi, M., Minghetti, L., Licastro, F., Chiricolo, M. & Tomasi, V., Jan 1990, In : Agents and Actions. 29, 1-2, p. 39-47 9 p.

Research output: Contribution to journalArticle

Proteasome modulation in brain: A new target for anti-aging drugs?

Mishto, M., Bellavista, E., Santoro, A. & Franceschi, C., Dec 2007, In : Central Nervous System Agents in Medicinal Chemistry. 7, 4, p. 236-240 5 p.

Research output: Contribution to journalArticle

Protective effect of N-acetylcysteine in tumor necrosis factor-α-induced apoptosis in U937 cells: The role of mitochondria

Cossarizza, A., Franceschi, C., Monti, D., Salvioli, S., Bellesia, E., Rivabene, R., Biondo, L., Rainaldi, G., Tinari, A. & Malorni, W., 1995, In : Experimental Cell Research. 220, 1, p. 232-240 9 p.

Research output: Contribution to journalArticle

Prothrombin gene mutation (G20210A) in healthy centenarians [3]

Sacchi, E., Duca, F., Franceschi, C. & Mari, D., 1999, In : Thrombosis and Haemostasis. 81, 6, p. 990-991 2 p.

Research output: Contribution to journalArticle

Purification and partial characterization of a mitogenic lectin from vicia sativa

Falasca, A., Franceschi, C., Rossi, C. A. & Stirpe, F., Mar 27 1979, In : BBA - Protein Structure. 577, 1, p. 71-81 11 p.

Research output: Contribution to journalArticle

Purification and partial characterization of serum monocytotropic factor, a platelet-derived cyclooxygenase-inducing polypeptide

Minghetti, L., Bartolini, G., Orlandi, M., Chiricolo, M., Licastro, F., Franceschi, C. & Tomasi, V., Feb 19 1988, In : Biochimica et Biophysica Acta (BBA)/Lipids and Lipid Metabolism. 958, 3, p. 315-322 8 p.

Research output: Contribution to journalArticle

Purification and properties of two lectins from the latex of the euphorbiaceous plants Hura crepitans L. (sand-box tree) and Euphorbia characias L. (Mediterranean spurge).

Barbieri, L., Falasca, A., Franceschi, C., Licastro, F., Rossi, C. A. & Stirpe, F., Dec 1 1983, In : Biochemical Journal. 215, 3, p. 433-439 7 p.

Research output: Contribution to journalArticle

Purines and cell death

Franceschi, C., Abbracchio, M. P., Barbieri, D., Ceruti, S., Ferrari, D., Iliou, J. P., Rounds, S., Schubert, P., Schulze-Lohoff, E., Rassendren, F. A., Staub, M., Volontè, C., Wakade, A. R. & Burnstock, G., 1996, In : Drug Development Research. 39, 3-4, p. 442-449 8 p.

Research output: Contribution to journalArticle

Quality control data of physiological and immunological biomarkers measured in serum and plasma

Jansen, E., Beekhof, P., Cremers, J., Weinberger, B., Fiegl, S., Toussaint, O., Bernhard, J., Gonos, E., Capri, M., Franceschi, C., Sikora, E., Moreno-Villanueva, M., Breusing, N., Grune, T., Bürkle, A. & Dollé, M. E. T., Jan 30 2015, In : Mechanisms of Ageing and Development. 151, p. 54-59 6 p.

Research output: Contribution to journalArticle

Quantifying the relevance of different mediators in the human immune cell network

Tieri, P., Valensin, S., Latora, V., Castellani, G. C., Marchiori, M., Remondini, D. & Franceschi, C., Apr 15 2005, In : Bioinformatics. 21, 8, p. 1639-1643 5 p.

Research output: Contribution to journalArticle

Quinazolinedione SIRT6 inhibitors sensitize cancer cells to chemotherapeutics

Sociali, G., Galeno, L., Parenti, M. D., Grozio, A., Bauer, I., Passalacqua, M., Boero, S., Donadini, A., Millo, E., Bellotti, M., Sturla, L., Damonte, P., Puddu, A., Ferroni, C., Varchi, G., Franceschi, C., Ballestrero, A., Poggi, A., Bruzzone, S., Nencioni, A. & 1 others, Del Rio, A., Aug 24 2015, In : European Journal of Medicinal Chemistry. 102, p. 530-539 10 p.

Research output: Contribution to journalArticle

Recent advances in human gene-longevity association studies

De Benedictis, G., Tan, Q., Jeune, B., Christensen, K., Ukraintseva, S. V., Bonafè, M., Franceschi, C., Vaupel, J. W. & Yashin, A. I., Jul 15 2001, In : Mechanisms of Ageing and Development. 122, 9, p. 909-920 12 p.

Research output: Contribution to journalArticle

Reconfiguration of DNA methylation in aging

Zampieri, M., Ciccarone, F., Calabrese, R., Franceschi, C., Bürkle, A. & Caiafa, P., Nov 1 2015, In : Mechanisms of Ageing and Development. 151, p. 60-70 11 p.

Research output: Contribution to journalArticle

Recovery from 6-month spaceflight at the International Space Station: muscle-related stress into a proinflammatory setting

Capri, M., Morsiani, C., Santoro, A., Moriggi, M., Conte, M., Martucci, M., Bellavista, E., Fabbri, C., Giampieri, E., Albracht, K., Flück, M., Ruoss, S., Brocca, L., Canepari, M., Longa, E., Di Giulio, I., Bottinelli, R., Cerretelli, P., Salvioli, S., Gelfi, C. & 3 others, Franceschi, C., Narici, M. & Rittweger, J., Apr 1 2019, In : FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 33, 4, p. 5168-5180 13 p.

Research output: Contribution to journalArticle

Open Access

Recovery from 6-month spaceflight at the International Space Station: Muscle-related stress into a proinflammatory setting

Capri, M., Morsiani, C., Santoro, A., Moriggi, M., Conte, M., Martucci, M., Bellavista, E., Fabbri, C., Giampieri, E., Albracht, K., Flück, M., Ruoss, S., Brocca, L., Canepari, M., Longa, E., Giulio, I. D., Bottinelli, R., Cerretelli, P., Salvioli, S., Gelfi, C. & 3 others, Franceschi, C., Narici, M. & Rittweger, J., 2019, In : FASEB Journal. 33, 4, p. 5168-5180 13 p.

Research output: Contribution to journalArticle

Recovery of human lymphocytes damaged with γradiation or enzymatically produced oxygen radicals: Different effects of poly(ADP-ribosyl)polymerase inhibitors

Marini, M., Zunica, G., Tamba, M., Cossarizza, A., Monti, D. & Franceschi, C., 1990, In : International Journal of Radiation Biology. 58, 2, p. 279-291 13 p.

Research output: Contribution to journalArticle

Reduced expression levels of the senescence biomarker clusterin/ apolipoprotein J in lymphocytes from healthy centenarians

Trougakos, I. P., Petropoulou, C., Franceschi, C. & Gonos, E. S., May 2006, In : Annals of the New York Academy of Sciences. 1067, 1, p. 294-300 7 p.

Research output: Contribution to journalArticle

Reduced susceptibility to peroxidation of erythrocyte plasma membranes from centenarians

Rabini, R. A., Moretti, N., Staffolani, R., Salvolini, E., Nanetti, L., Franceschi, C. & Mazzanti, L., 2002, In : Experimental Gerontology. 37, 5, p. 657-663 7 p.

Research output: Contribution to journalArticle

Regulation of thromboxane A2 biosynthesis in platelet-free human monocytes and the possible role of polypeptide growth factor(s) in the induction of cyclooxygenase system

Bartolini, G., Orlandi, M., Chiricolo, M., Minghetti, L., Guerrini, F., Fidan, M., Franceschi, C. & Tomasi, V., May 21 1986, In : Biochimica et Biophysica Acta (BBA)/Lipids and Lipid Metabolism. 876, 3, p. 486-493 8 p.

Research output: Contribution to journalArticle

Regulatory T cells from patients with end-stage organ disease can be isolated, expanded and cryopreserved according good manufacturing practice improving their function

Ulbar, F., Montemurro, T., Jofra, T., Capri, M., Comai, G., Bertuzzo, V., Lavazza, C., Mandelli, A., Viganò, M., Budelli, S., Bacalini, M. G., Pirazzini, C., Garagnani, P., Giudice, V., Sollazzo, D., Curti, A., Arpinati, M., La Manna, G., Cescon, M., Pinna, A. D. & 5 others, Franceschi, C., Battaglia, M., Giordano, R., Catani, L. & Lemoli, R. M., Aug 5 2019, In : Journal of Translational Medicine. 17, 1, 250.

Research output: Contribution to journalArticle

Open Access

Relationship between corticotropin-releasing factor and interleukin-2: Evolutionary evidence

Ottaviani, E., Franchini, A., Caselgrandi, E., Cossarizza, A. & Franceschi, C., Aug 29 1994, In : FEBS Letters. 351, 1, p. 19-21 3 p.

Research output: Contribution to journalArticle

Remodelling of biological parameters during human ageing: Evidence for complex regulation in longevity and in type 2 diabetes

Spazzafumo, L., Olivieri, F., Abbatecola, A. M., Castellani, G., Monti, D., Lisa, R., Galeazzi, R., Sirolla, C., Testa, R., Ostan, R., Scurti, M., Caruso, C., Vasto, S., Vescovini, R., Ogliari, G., Mari, D., Lattanzio, F. & Franceschi, C., Apr 2013, In : Age. 35, 2, p. 419-429 11 p.

Research output: Contribution to journalArticle

Replication studies in longevity: Puzzling findings in Danish centenarians at the 3′ APOB-VNTR locus

Varcasia, O., Garasto, S., Rizza, T., Andersen-Ranberg, K., Jeune, B., Bathum, L., Andreev, K., Tan, Q., Yashin, A. I., Bonafè, M., Franceschi, C. & De Benedictis, G., 2001, In : Annals of Human Genetics. 65, 4, p. 371-376 6 p.

Research output: Contribution to journalArticle

Reply from Franceschi et al.

Franceschi, C., Monti, D., Cossarizza, A. & Sansoni, P., 1995, In : Immunology Today. 16, 11, p. 549-550 2 p.

Research output: Contribution to journalArticle

Report from the second cytomegalovirus and immunosenescence workshop

Wills, M., Akbar, A., Beswick, M., Bosch, J. A., Caruso, C., Colonna-Romano, G., Dutta, A., Franceschi, C., Fulop, T., Gkrania-Klotsas, E., Goronzy, J., Griffiths, S. J., Henson, S. M., Herndler-Brandstetter, D., Hill, A., Kern, F., Klenerman, P., Macallan, D., Macaulay, R., Maier, A. B. & 19 others, Mason, G., Melzer, D., Morgan, M., Moss, P., Nikolich-Zugich, J., Pachnio, A., Riddell, N., Roberts, R., Sansoni, P., Sauce, D., Sinclair, J., Solana, R., Strindhall, J., Trzonkowski, P., van Lier, R., Vescovini, R., Wang, G., Westendorp, R. & Pawelec, G., Oct 28 2011, In : Immunity and Ageing. 8, 10.

Research output: Contribution to journalArticle

Reprint of: A parallel randomized trial on the effect of a healthful diet on inflammageing and its consequences in European elderly people: Design of the NU-AGE dietary intervention study

Berendsen, A., Santoro, A., Pini, E., Cevenini, E., Ostan, R., Pietruszka, B., Rolf, K., Cano, N., Caille, A., Lyon-Belgy, N., Fairweather-Tait, S., Feskens, E., Franceschi, C. & de Groot, C. P. G. M., 2014, In : Mechanisms of Ageing and Development. 136-137, p. 14-21 8 p.

Research output: Contribution to journalArticle

Reprint of: Musculoskeletal system in the old age and the demand for healthy ageing biomarkers

Collino, S., Martin, F. P., Karagounis, L. G., Horcajada, M. N., Moco, S., Franceschi, C., Kussmann, M. & Offord, E., 2014, In : Mechanisms of Ageing and Development. 136-137, p. 94-100 7 p.

Research output: Contribution to journalArticle