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Changes in circulating B cells and immunoglobulin classes and subclasses in a healthy aged population

Paganelli, R., Quinti, I., Fagiolo, U., Cossarizza, A., Ortolani, C., Guerra, E., Sansoni, P., Pucillo, L. P., Scala, E., Cozzi, E., Bertollo, L., Monti, D. & Franceschi, C., 1992, In : Clinical and Experimental Immunology. 90, 2, p. 351-354 4 p.

Research output: Contribution to journalArticle

Charting the NF-κB pathway interactome map

Tieri, P., Termanini, A., Bellavista, E., Salvioli, S., Capri, M. & Franceschi, C., Mar 5 2012, In : PLoS One. 7, 3, e32678.

Research output: Contribution to journalArticle

Chemokines, sTNF-Rs and sCD30 serum levels in healthy aged people and centenarians

Gerli, R., Monti, D., Bistoni, O., M. Mazzone, A., Peri, G., Cossarizza, A., Di Gioacchino, M., E. F. Cesarotti, M., Doni, A., Mantovani, A., Franceschi, C. & Paganelli, R., Jan 20 2001, In : Mechanisms of Ageing and Development. 121, 1-3, p. 37-46 10 p.

Research output: Contribution to journalArticle

Cholesteryl ester transfer protein (CETP) I405V polymorphism and longevity in Italian centenarians

Cellini, E., Nacmias, B., Olivieri, F., Ortenzi, L., Tedde, A., Bagnoli, S., Petruzzi, C., Franceschi, C. & Sorbi, S., Jun 2005, In : Mechanisms of Ageing and Development. 126, 6-7, p. 826-828 3 p.

Research output: Contribution to journalArticle

Chronic antigenic load and apoptosis in immunosenescence

Ginaldi, L., De Martinis, M., Monti, D. & Franceschi, C., Feb 2005, In : Trends in Immunology. 26, 2, p. 79-84 6 p.

Research output: Contribution to journalArticle

Chronic antigenic stress, immunosenescence and human survivorship over the 3 last centuries: Heuristic value of a mathematical model

Mariani, L., Turchetti, G. & Franceschi, C., Apr 1 2003, In : Mechanisms of Ageing and Development. 124, 4, p. 453-458 6 p.

Research output: Contribution to journalArticle

Chronic inflammation and the effect of IGF-I on muscle strength and power in older persons

Barbieri, M., Ferrucci, L., Ragno, E., Corsi, A., Bandinelli, S., Bonafé, M., Olivieri, F., Giovagnetti, S., Franceschi, C., Guralnik, J. M. & Paolisso, G., Mar 1 2003, In : American Journal of Physiology - Endocrinology and Metabolism. 284, 3 47-3

Research output: Contribution to journalArticle

Chronic renal impairment and DDAH2-1151 A/C polymorphism determine ADMA levels in type 2 diabetic subjects

Marra, M., Marchegiani, F., Ceriello, A., Sirolla, C., Boemi, M., Franceschi, C., Spazzafumo, L., Testa, I., Bonfigli, A. R., Cucchi, M. & Testa, R., Apr 2013, In : Nephrology Dialysis Transplantation. 28, 4, p. 964-971 8 p.

Research output: Contribution to journalArticle

Circulating levels of adipokines and IGF-1 are associated with skeletal muscle strength of young and old healthy subjects

Bucci, L., Yani, S. L., Fabbri, C., Bijlsma, A. Y., Maier, A. B., Meskers, C. G., Narici, M. V., Jones, D. A., McPhee, J. S., Seppet, E., Gapeyeva, H., Pääsuke, M., Sipilä, S., Kovanen, V., Stenroth, L., Musarò, A., Hogrel, J. Y., Barnouin, Y., Butler-Browne, G., Capri, M. & 2 others, Franceschi, C. & Salvioli, S., Jun 2013, In : Biogerontology. 14, 3, p. 261-272 12 p.

Research output: Contribution to journalArticle

Circulating miR-21, miR-146a and Fas ligand respond to postmenopausal estrogen-based hormone replacement therapy - A study with monozygotic twin pairs

Kangas, R., Pöllänen, E., Rippo, M. R., Lanzarini, C., Prattichizzo, F., Niskala, P., Jylhävä, J., Sipilä, S., Kaprio, J., Procopio, A. D., Capri, M., Franceschi, C., Olivieri, F. & Kovanen, V., Dec 5 2014, In : Mechanisms of Ageing and Development. 143-144, p. 1-8 8 p.

Research output: Contribution to journalArticle

Circulating mitochondrial DNA increases with age and is a familiar trait: Implications for "inflamm-aging"

Pinti, M., Cevenini, E., Nasi, M., De Biasi, S., Salvioli, S., Monti, D., Benatti, S., Gibellini, L., Cotichini, R., Stazi, M. A., Trenti, T., Franceschi, C. & Cossarizza, A., 2014, In : European Journal of Immunology. 44, 5, p. 1552-1562 11 p.

Research output: Contribution to journalArticle

Cloning of differentially expressed genes in skin fibroblasts from centenarians

Chondrogianni, N., Simoes, D. D. C. M., Franceschi, C. & Gonos, E. S., Nov 2004, In : Biogerontology. 5, 6, p. 401-409 9 p.

Research output: Contribution to journalArticle

Cognitive status in the oldest old and centenarians: a condition crucial for quality of life methodologically difficult to assess

Arosio, B., Ostan, R., Mari, D., Damanti, S., Ronchetti, F., Arcudi, S., Scurti, M., Monti, D. & Franceschi, C., 2017, In : Mechanisms of Ageing and Development. 165, PtB, p. 185-194 10 p.

Research output: Contribution to journalArticle

Colorectal cancer microenvironment: Among nutrition, gut microbiota, inflammation and epigenetics

Garagnani, P., Pirazzini, C. & Franceschi, C., 2013, In : Current Pharmaceutical Design. 19, 4, p. 765-778 14 p.

Research output: Contribution to journalArticle

Combating inflammaging through a Mediterranean whole diet approach: The NU-AGE project's conceptual framework and design

Santoro, A., Pini, E., Scurti, M., Palmas, G., Berendsen, A., Brzozowska, A., Pietruszka, B., Szczecinska, A., Cano, N., Meunier, N., de Groot, C. P. G. M., Feskens, E., Fairweather-Tait, S., Salvioli, S., Capri, M., Brigidi, P., Franceschi, C., Fabbri, C., Bertarelli, C., Izzi, M. & 50 others, Mazzocchi, M., Chardigny, J. M., Morio, B., Rossi, D., Notarfonso, M., O'Toole, P. W., Cashman, K., Carding, S. R., Nicoletti, C., Jacobs, D., Xipsiti, M., Fernandez, L., Wills, J., Irz, X., Kuosmanen, N., Gonos, E. S., Voutetakis, K., Salmon, M., Toussaint, O., Traill, B. W., Nocella, G., Caracciolo, B., Xu, W., Mikko Ikonen, I., Tuure, T., Brummer, R., Kadi, F., Breton, S., Triomphe, M., Magario, G., Villani, F., Pancrazio, A., Teufner, B., Stocker, J., Echevarría, F. J., Iglesias, J. R., Smrž, F., Krejcirova, L., Koytsomitropoulou, E., Georgakidis, K., Yornuk, R., Ucar, C., Van Ommen, B., Bouwman, J., Collino, S., Jankovics, C., Losó, A., de Vos, W., Fuentes, S. & Commelin, E., 2014, In : Mechanisms of Ageing and Development. 136-137, p. 3-13 11 p.

Research output: Contribution to journalArticle

Combination of biomarkers to predict mortality in elderly patients with myocardial infarction

Olivieri, F., Spazzafumo, L., Antonicelli, R., Marchegiani, F., Cardelli, M., Sirolla, C., Galeazzi, R., Giovagnetti, S., Mocchegiani, E. & Franceschi, C., Apr 2008, In : Mechanisms of Ageing and Development. 129, 4, p. 231-237 7 p.

Research output: Contribution to journalArticle

Common evolutionary origin of the immune and neuroendocrine systems: from morphological and functional evidence to in silico approaches

Ottaviani, E., Malagoli, D. & Franceschi, C., Nov 2007, In : Trends in Immunology. 28, 11, p. 497-502 6 p.

Research output: Contribution to journalArticle

Compared effects of N-hydroxyurethan, urethan and hydroxyurea on DNA synthesis. In vivo and in vitro studies

Perocco, P., Ferreri, A. M., Franceschi, C., Grilli, S., Rocchi, P., Arfellini, G. & Prodi, G., May 1977, In : Zeitschrift für Krebsforschung und Klinische Onkologie. 89, 1, p. 99-106 8 p.

Research output: Contribution to journalArticle

Complex alteration of thyroid function in healthy centenarians

Mariotti, S., Barbesino, G., Caturegli, P., Bartalena, L., Sansoni, P., Fagnoni, F., Monti, D., Fagiolo, U., Franceschi, C. & Pinchera, A., Nov 1993, In : Journal of Clinical Endocrinology and Metabolism. 77, 5, p. 1130-1134 5 p.

Research output: Contribution to journalArticle

Complex interplay between neutral and adaptive evolution shaped differential genomic background and disease susceptibility along the Italian peninsula

Sazzini, M., Gnecchi Ruscone, G. A., Giuliani, C., Sarno, S., Quagliariello, A., De Fanti, S., Boattini, A., Gentilini, D., Fiorito, G., Catanoso, M., Boiardi, L., Croci, S., Macchioni, P., Mantovani, V., Di Blasio, A. M., Matullo, G., Salvarani, C., Franceschi, C., Pettener, D., Garagnani, P. & 1 others, Luiselli, D., Sep 1 2016, In : Scientific Reports. 6, 32513.

Research output: Contribution to journalArticle

Complex interplay between neutral and adaptive evolution shaped differential genomic background and disease susceptibility along the Italian peninsula

Sazzini, M., Gnecchi Ruscone, G. A., Giuliani, C., Sarno, S., Quagliariello, A., De Fanti, S., Boattini, A., Gentilini, D., Fiorito, G., Catanoso, M. G., Boiardi, L., Croci, S., Macchioni, P., Mantovani, W., Di Blasio, A. M., Matullo, G., Salvarani, C., Franceschi, C., Pettener, D., Garagnani, P. & 1 others, Luiselli, D., Sep 1 2016, In : Scientific Reports. 6, 32513.

Research output: Contribution to journalArticle

Complex interplay between neutral and adaptive evolution shaped differential genomic background and disease susceptibility along the Italian peninsula

Sazzini, M., Gnecchi Ruscone, G. A., Giuliani, C., Sarno, S., Quagliariello, A., De Fanti, S., Boattini, A., Gentilini, D., Fiorito, G., Catanoso, M. G., Boiardi, L., Croci, S., Macchioni, P., Mantovani, W., Di Blasio, A. M., Matullo, G., Salvarani, C., Franceschi, C., Pettener, D., Garagnani, P. & 1 others, Luiselli, D., Sep 1 2016, In : Scientific Reports. 6, 32513.

Research output: Contribution to journalArticle

Complexity of anti-immunosenescence strategies in humans

Capri, M., Monti, D., Salvioli, S., Lescai, F., Pierini, M., Altilia, S., Sevini, F., Valensin, S., Ostan, R., Bucci, L. & Franceschi, C., Oct 2006, In : Artificial Organs. 30, 10, p. 730-742 13 p.

Research output: Contribution to journalArticle

Complex patterns of gene expression in human T cells during in vivo aging

Remondini, D., Salvioli, S., Francesconi, M., Pierini, M., Mazzatti, D. J., Powell, J. R., Zironi, I., Bersani, F., Castellani, G. & Franceschi, C., Oct 2010, In : Molecular BioSystems. 6, 10, p. 1983-1992 10 p.

Research output: Contribution to journalArticle

Congenital disorders sharing oxidative stress and cancer proneness as phenotypic hallmarks: Prospects for joint research in pharmacology

Pagano, G., Korkina, L. G., Brunk, U. T., Chessa, L., Degan, P., Del Principe, D., Kelly, F. J., Malorni, W., Pallardó, F., Pasquier, C., Scovassi, I., Zatterale, A. & Franceschi, C., Sep 1998, In : Medical Hypotheses. 51, 3, p. 253-266 14 p.

Research output: Contribution to journalArticle

Control of apoptosis by the cellular ATP level

Richter, C., Schweizer, M., Cossarizza, A. & Franceschi, C., Jan 8 1996, In : FEBS Letters. 378, 2, p. 107-110 4 p.

Research output: Contribution to journalArticle

Correction: Analysis of population substructure in two sympatric populations of Gran Chaco, Argentina (PLoS ONE)

Sevini, F., Yao, D. Y., Lomartire, L., Barbieri, A., Vianello, D., Ferri, G., Moretti, E., Dasso, M. C., Garagnani, P., Pettener, D., Franceschi, C., Luiselli, D. & Franceschi, Z. A., Jan 3 2014, In : PLoS One. 9, 1

Research output: Contribution to journalArticle

Correction to: Which elderly newly diagnosed glioblastoma patients can benefit from radiotherapy and temozolomide? A PERNO prospective study

Franceschi, E., Depenni, R., Paccapelo, A., Ermani, M., Faedi, M., Sturiale, C., Michiara, M., Servadei, F., Pavesi, G., Urbini, B., Pisanello, A., Crisi, G., Baruzzi, A., Baruzzi, A., Albani, F., Michelucci, R., Cavallo, M., Tosoni, A., Cavallo, M., Valentini, A. & 31 others, Pisanello, A., Testoni, S., Agati, R., Bacci, A., Baldin, E., Barbieri, E., Bisulli, F., Carelli, V., Crisci, M., de Biase, D., Franceschi, C., Leonardi, M., Marucci, G., Morandi, L., Mostacci, B., Palandri, G., Pasini, E., Riguzzi, P., Tinuper, P., Gentili, G., Faedi, M., Zumaglini, F., Amadori, A., Bertolini, F., Pinna, G., Ragazzi, M., Rizzi, R., Seraceni, S., Giorgi, C., Montanari, E. & The Perno Study Group, Nov 9 2017, (Accepted/In press) In : Journal of Neuro-Oncology. p. 1-2 2 p.

Research output: Contribution to journalArticle

Correlation analysis reveals the emergence of coherence in the gene expression dynamics following system perturbation

Neretti, N., Remondini, D., Tatar, M., Sedivy, J. M., Pierini, M., Mazzatti, D., Powell, J., Franceschi, C. & Castellani, G. C., Mar 8 2007, In : BMC Bioinformatics. 8, SUPPL. 1, S16.

Research output: Contribution to journalArticle

Corrigendum to "Immune parameters identify Italian centenarians with a longer five-year survival independent of their health and functional status" [Exp. Gerontol. 54C (2014) 14-20] DOI: 10.1016/j.exger.2014.01.023

Bucci, L., Ostan, R., Giampieri, E., Cevenini, E., Pini, E., Scurti, M., Vescovini, R., Sansoni, P., Caruso, C., Mari, D., Ronchetti, F., Borghi, M. O., Ogliari, G., Grossi, C., Capri, M., Salvioli, S., Castellani, G., Franceschi, C. & Monti, D., Jan 1 2016, In : Experimental Gerontology. 73, p. 121 1 p.

Research output: Contribution to journalArticle

Corticotropin-releasing hormone modulates cytokines release in cultured human peripheral blood mononuclear cells

Angioni, S., Petraglia, F., Gallinelli, A., Cossarizza, A., Franceschi, C., Muscettola, M., Genazzani, A. D., Surico, N. & Genazzani, A. R., 1993, In : Life Sciences. 53, 23, p. 1735-1742 8 p.

Research output: Contribution to journalArticle

Curcumin in cell death processes: A challenge for CAM of age-related pathologies

Salvioli, S., Sikora, E., Cooper, E. L. & Franceschi, C., Jun 2007, In : Evidence-based Complementary and Alternative Medicine. 4, 2, p. 181-190 10 p.

Research output: Contribution to journalArticle

Cytogenetic effects induced by extremely low frequency pulsed magnetic fields in lymphocytes from Turner's syndrome subjects

Scarfì, M. R., Prisco, F., Lioi, M. B., Zeni, O., Della Noce, M., Di Pietro, R., Franceschi, C., Iafusco, D., Motta, M. & Bersani, F., Aug 1997, In : Bioelectrochemistry and Bioenergetics. 43, 2, p. 221-226 6 p.

Research output: Contribution to journalArticle

Cytokines, aging and evolution: The problem of promiscuity

Franceschi, C., Paganelli, R., Fagiolo, U. & Ottaviani, E., 1994, In : International Journal of Immunopathology and Pharmacology. 7, 3, p. 227-233 7 p.

Research output: Contribution to journalArticle

Cytokines and Evolution: In Vitro Effects of IL-1α, IL-1β, TNF-α and TNF-β on an Ancestral Type of Stress Response

Ottaviani, E., Caselgrandi, E. & Franceschi, C., Feb 6 1995, In : Biochemical and Biophysical Research Communications. 207, 1, p. 288-292 5 p.

Research output: Contribution to journalArticle

Cytometric analysis of immunosenescence

Cossarizza, A., Ortolani, C., Monti, D. & Franceschi, C., Apr 1 1997, In : Cytometry. 27, 4, p. 297-313 17 p.

Research output: Contribution to journalArticle

Cytoskeleton alterations of erythrocytes from patients with Fanconi's anemia

Malorni, W., Straface, E., Pagano, G., Monti, D., Zatterale, A., Del Principe, D., Deeva, I. B., Franceschi, C., Masella, R. & Korkina, L. G., Feb 25 2000, In : FEBS Letters. 468, 2-3, p. 125-128 4 p.

Research output: Contribution to journalArticle

Cytotoxicity and cell death: studies on molluscan cells and evolutionary considerations.

Monti, D., Salvioli, S., Cossarizza, A., Franceschi, C. & Ottaviani, E., 1992, In : Acta Biologica Hungarica. 43, 1-4, p. 287-291 5 p.

Research output: Contribution to journalArticle

Decreased epigenetic age of PBMCs from Italian semi-supercentenarians and their offspring

Horvath, S., Pirazzini, C., Bacalini, M. G., Gentilini, D., Di Blasio, A. M., Delledonne, M., Mari, D., Arosio, B., Monti, D., Passarino, G., De Rango, F., D'Aquila, P., Giuliani, C., Marasco, E., Collino, S., Descombes, P., Garagnani, P. & Franceschi, C., 2015, In : Aging. 7, 12, p. 1159-1170 12 p.

Research output: Contribution to journalArticle

Decreased susceptibility to oxidative stress-induced apoptosis of peripheral blood mononuclear cells from healthy elderly and centenarians

Monti, D., Salvioli, S., Capri, M., Malorni, W., Straface, E., Cossarizza, A., Botti, B., Piacentini, M., Baggio, G., Barbi, C., Valensin, S., Bonafè, M. & Franceschi, C., Jan 20 2001, In : Mechanisms of Ageing and Development. 121, 1-3, p. 239-250 12 p.

Research output: Contribution to journalArticle

Decrease in mitochondrial energy coupling by thyroid hormones: A physiological effect rather than a pathological hyperthyroidism consequence

Bobyleva, V., Pazienza, T. L., Maseroli, R., Tomasi, A., Salvioli, S., Cossarizza, A., Franceschi, C. & Skulachev, V. P., Jul 3 1998, In : FEBS Letters. 430, 3, p. 409-413 5 p.

Research output: Contribution to journalArticle

Defective self-recognition in subjects of far-advanced age

Licastro, F., Tabacchi, P. L., Chiricolo, M., Parente, R., Cenci, M., Barboni, F. & Franceschi, C., 1983, In : Gerontology. 29, 1, p. 64-72 9 p.

Research output: Contribution to journalArticle

Deficiency of autologous mixed lymphocyte reactions and serum thymic factor level in Down's syndrome

Franceschi, C., Licastro, F., Chiricolo, M., Bonetti, F., Zannotti, M., Fabris, N., Mocchegiani, E., Fantini, M. P., Paolucci, P. & Masi, M., 1981, In : Journal of Immunology. 126, 6, p. 2161-2164 4 p.

Research output: Contribution to journalArticle

DEFICIT SELETTIVO DI IgA E INFEZIONI RICORRENTI. STUDIO CLINICO E IMMUNOLOGICO DI TRE CASI

Translated title of the contribution: Selective IgA deficiency and recurrent infections. (Immunological clinical study of three cases)Masi, M., Paolucci, P. & Franceschi, C., 1977, In : Clinical Pediatrics. 59, 7, p. 253-271 19 p.

Research output: Contribution to journalArticle

Definition of miRNAs Expression Profile in Glioblastoma Samples: The Relevance of Non-Neoplastic Brain Reference

Visani, M., de Biase, D., Marucci, G., Taccioli, C., Baruzzi, A., Pession, A., Baruzzi, A., Albani, F., Calbucci, F., D'Alessandro, R., Michelucci, R., Brandes, A., EusebiEusebi, V., Ceruti, S., Fainardi, E., Tamarozzi, R., Emiliani, E., Cavallo, M., Franceschi, E., Tosoni, A. & 124 others, Cavallo, M., Fiorica, F., Valentini, A., Depenni, R., Mucciarini, C., Crisi, G., Sasso, E., Biasini, C., Cavanna, L., Guidetti, D., Marcello, N., Pisanello, A., Cremonini, A. M., Guiducci, G., de Pasqua, S., Testoni, S., Agati, R., Ambrosetto, G., Bacci, A., Baldin, E., Baldrati, A., Barbieri, E., Bartolini, S., Bellavista, E., Bisulli, F., Bonora, E., Bunkheila, F., Carelli, V., Crisci, M., Dall'Occa, P., Ferro, S., Franceschi, C., Frezza, G., Grasso, V., Leonardi, M., Mostacci, B., Palandri, G., Pasini, E., Pastore Trossello, M., Poggi, R., Riguzzi, P., Rinaldi, R., Rizzi, S., Romeo, G., Spagnolli, F., Tinuper, P., Trocino, C., Cerasoli, S., Dall'Agata, M., Faedi, M., Frattarelli, M., Gentili, G., Giovannini, A., Iorio, P., Pasquini, U., Galletti, G., Guidi, C., Neri, W., Patuelli, A., Strumia, S., Casmiro, M., Gamboni, A., Rasi, F., Cruciani, G., Cenni, P., Dazzi, C., Guidi, A. R., Zumaglini, F., Amadori, A., Pasini, G., Pasquinelli, M., Pasquini, E., Polselli, A., Ravasio, A., Viti, B., Sintini, M., Ariatti, A., Bertolini, F., Bigliardi, G., Carpeggiani, P., Cavalleri, F., Meletti, S., Nichelli, P., Pettorelli, E., Pinna, G., Zunarelli, E., Artioli, F., Bernardini, I., Costa, M., Greco, G., Guerzoni, R., Stucchi, C., Iaccarino, C., Ragazzi, M., Rizzi, R., Zuccoli, G., Api, P., Cartei, F., Fallica, E., Granieri, E., Latini, F., Lelli, G., Monetti, C., Saletti, A., Schivalocchi, R., Seraceni, S., Tola, M. R., Urbini, B., Giorgi, C., Montanari, E., Cerasti, D., Crafa, P., Dascola, I., Florindo, I., Giombelli, E., Mazza, S., Ramponi, V., Servadei, F., Silini, E. M., Torelli, P., Immovilli, P., Morelli, N., Vanzo, C. & Nobile, C., Jan 29 2013, In : PLoS One. 8, 1, e55314.

Research output: Contribution to journalArticle

Demographic characteristics of sardinian centenarian genealogies: Preliminary results of the AKeA2 study

Lipsi, R. M., Caselli, G., Pozzi, L., Baggio, G., Carru, C., Franceschi, C., Vaupel, J. W. & Deiana, L., 2015, In : Demographic Research. 32, 1, p. 1049-1064 16 p.

Research output: Contribution to journalArticle