1969 …2020

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Gender specific association of genetic variation in peroxisome proliferator-activated receptor (PPAR)γ-2 with longevity

Barbieri, M., Bonafè, M., Rizzo, M. R., Ragno, E., Olivieri, F., Marchegiani, F., Franceschi, C. & Paolisso, G., Jul 2004, In : Experimental Gerontology. 39, 7, p. 1095-1100 6 p.

Research output: Contribution to journalArticle

Gene/longevity association studies at four autosomal loci (REN, THO, PARP, SOD2)

De Benedictis, G., Carotenuto, L., Carrieri, G., De Luca, M., Falcone, E., Rose, G., Cavalcanti, S., Corsonello, F., Feraco, E., Baggio, G., Bertolini, S., Mari, D., Mattace, R., Yashin, A. I., Bonafè, M. & Franceschi, C., Nov 1998, In : European Journal of Human Genetics. 6, 6, p. 534-541 8 p.

Research output: Contribution to journalArticle

Gene expression changes in human cells after exposure to mobile phone microwaves

Remondini, D., Nylund, R., Reivinen, J., De Gannes, F. P., Veyret, B., Lagroye, I., Haro, E., Trillo, M. A., Capri, M., Franceschi, C., Schlatterer, K., Gminski, R., Fitzner, R., Tauber, R., Schuderer, J., Kuster, N., Leszczynski, D., Bersani, F. & Maercker, C., Sep 2006, In : Proteomics. 6, 17, p. 4745-4754 10 p.

Research output: Contribution to journalArticle

Gene expression of cytokines and cytokine receptors is modulated by the common variability of the mitochondrial DNA in cybrid cell lines

Bellizzi, D., Cavalcante, P., Taverna, D., Rose, G., Passarino, G., Salvioli, S., Franceschi, C. & De Benedictis, G., Aug 2006, In : Genes to Cells. 11, 8, p. 883-891 9 p.

Research output: Contribution to journalArticle

Gene polymorphism affecting α1-antichymotrypsin and interleukin-1 plasma levels increases Alzheimer's disease risk

Licastro, F., Pedrini, S., Ferri, C., Casadei, V., Govoni, M., Pession, A., Sciacca, F. L., Veglia, F., Annoni, G., Bonafè, M., Olivieri, F., Franceschi, C. & Grimaldi, L. M. E., 2000, In : Annals of Neurology. 48, 3, p. 388-391 4 p.

Research output: Contribution to journalArticle

Gene polymorphisms predicting high plasma levels of coagulation and fibrinolysis proteins: A study in centenarians

Mannucci, P. M., Mari, D., Merati, G., Peyvandi, F., Tagliabue, L., Sacchi, E., Taioli, E., Sansoni, P., Bertolini, S. & Franceschi, C., 1997, In : Arteriosclerosis, Thrombosis, and Vascular Biology. 17, 4, p. 755-759 5 p.

Research output: Contribution to journalArticle

Genes, ageing and longevity in humans: Problems, advantages and perspectives

Salvioli, S., Olivieri, F., Marchegiani, F., Cardelli, M., Santoro, A., Bellavista, E., Mishto, M., Invidia, L., Capri, M., Valensin, S., Sevini, F., Cevenini, E., Celani, L., Lescai, F., Gonos, E., Caruso, C., Paolisso, G., De Benedictis, G., Monti, D. & Franceschi, C., Dec 2006, In : Free Radical Research. 40, 12, p. 1303-1323 21 p.

Research output: Contribution to journalArticle

Genes, demography, and life span: The contribution of demographic data in genetic studies on aging and longevity

Yashin, A. I., De Benedictis, G., Vaupel, J. W., Tan, Q., Andreev, K. F., Iachine, I. A., Bonafe, M., DeLuca, M., Valensin, S., Carotenuto, L. & Franceschi, C., 1999, In : American Journal of Human Genetics. 65, 4, p. 1178-1193 16 p.

Research output: Contribution to journalArticle

Genes and longevity: Lessons from studies of centenarians

Yashin, A. I., De Benedictis, G., Vaupel, J. W., Tan, Q., Andreev, K. F., Iachine, I. A., Bonafe, M., Valensin, S., De Luca, M., Carotenuto, L. & Franceschi, C., Jul 2000, In : Journals of Gerontology - Series A Biological Sciences and Medical Sciences. 55, 7

Research output: Contribution to journalArticle

Genes associated with Type 2 Diabetes and vascular complications

Montesanto, A., Bonfigli, A. R., Crocco, P., Garagnani, P., De Luca, M., Boemi, M., Marasco, E., Pirazzini, C., Giuliani, C., Franceschi, C., Passarino, G., Testa, R., Olivieri, F. & Rose, G., Feb 1 2018, In : Aging. 10, 2, p. 178-196 19 p.

Research output: Contribution to journalArticle

Genes involved in immune response/inflammation, IGF1/insulin pathway and response to oxidative stress play a major role in the genetics of human longevity: The lesson of centenarians

Franceschi, C., Olivieri, F., Marchegiani, F., Cardelli, M., Cavallone, L., Capri, M., Salvioli, S., Valensin, S., De Benedictis, G., Di Iorio, A., Caruso, C., Paolisso, G. & Monti, D., Feb 2005, In : Mechanisms of Ageing and Development. 126, 2, p. 351-361 11 p.

Research output: Contribution to journalArticle

Genes of human longevity: An endless quest?

Capri, M., Santoro, A., Garagnani, P., Bacalini, M. G., Pirazzini, C., Olivieri, F., Procopio, A., Salvioli, S. & Franceschi, C., 2014, In : Current Vascular Pharmacology. 12, 5, p. 707-717 11 p.

Research output: Contribution to journalArticle

Genetic analysis of paraoxonase (PON1) locus reveals an increased frequency of Arg192 allele in centenarians

Bonafè, M., Marchegiani, F., Cardelli, M., Olivieri, F., Cavallone, L., Giovagnetti, S., Pieri, C., Marra, M., Antonicelli, R., Troiano, L., Gueresi, P., Passeri, G., Berardelli, M., Paolisso, G., Barbieri, M., Tesei, S., Lisa, R., De Benedictis, G. & Franceschi, C., 2002, In : European Journal of Human Genetics. 10, 5, p. 292-296 5 p.

Research output: Contribution to journalArticle

Genetic and environmental influences on serum levels of immunoglobulins and complement components in monozygotic and dizygotic twins

Di Franco, P., Brai, M., Misiano, G., Piazza, A. M., Giorgi, G., Cossarizza, A. & Franceschi, C., 1988, In : Journal of Clinical and Laboratory Immunology. 27, 1, p. 5-10 6 p.

Research output: Contribution to journalArticle

Genetic epidemiologic studies on age-specified traits

Bailey-Wilson, J., Baron, J., Cawthon, R., Christian, J. C., Corder, E. H., Franceschi, C., Kestenbaum, B., Kruglyak, L., Lauderdale, D. S., Lubitz, J., Martin, G. M., McClearn, G. E., McGue, M., Miles, T., Mineau, G., Ouellett, G., Pedersen, N. L., Preston, S. H., Page, W. F., Province, M. & 8 others, Schachter, F., Schork, N. J., Vaupel, J. W., Vijg, J., Wallace, R., Wang, E., Wijsman, E. M. & Hadley, E., Dec 1 2000, In : American Journal of Epidemiology. 152, 11, p. 1003-1008 6 p.

Research output: Contribution to journalArticle

Genetic polymorphisms of Fas (CD95) and FasL (CD178) in human longevity: Studies on centenarians

Pinti, M., Troiano, L., Nasi, M., Moretti, L., Monterastelli, E., Mazzacani, A., Mussi, C., Ventura, P., Olivieri, F., Franceschi, C., Salvioli, G. & Cossarizza, A., 2002, In : Cell Death and Differentiation. 9, 4, p. 431-438 8 p.

Research output: Contribution to journalArticle

Genetic polymorphisms of inflammatory cytokines and myocardial infarction in the elderly

Olivieri, F., Antonicelli, R., Cardelli, M., Marchegiani, F., Cavallone, L., Mocchegiani, E. & Franceschi, C., Jun 2006, In : Mechanisms of Ageing and Development. 127, 6, p. 552-559 8 p.

Research output: Contribution to journalArticle

Genetics and anthropology in studies on aging and chagas disease

Franceschi, C., Yao, D. Y., Sevini, F., Santoro, A., Luiselli, D., Pettener, D., Ferri, G., Dasso, M. C., De La Hoz, R. P., Moretti, E., Basso, B., Castro, I., Ciannameo, A. & Franceschi, Z., 2010, In : Journal of anthropological sciences = Rivista di antropologia : JASS / Istituto italiano di antropologia. 88, p. 245-250 6 p.

Research output: Contribution to journalArticle

Genetics of neurodegenerative disorders.

Caruso, C., Franceschi, C. & Licastro, F., 2003, In : New England Journal of Medicine. 349, 2

Research output: Contribution to journalArticle

Genetics of neurodegenerative disorders [4] (multiple letters)

Caruso, C., Franceschi, C., Licastro, F., Nussbaum, R. & Ellis, C., Jul 10 2003, In : New England Journal of Medicine. 349, 2, p. 193-194 2 p.

Research output: Contribution to journalArticle

Genome-wide association meta-analysis of human longevity identifies a novel locus conferring survival beyond 90 years of age

Deelen, J., Beekman, M., Uh, H. W., Broer, L., Ayers, K. L., Tan, Q., Kamatani, Y., Bennet, A. M., Tamm, R., Trompet, S., Guobjartsson, D. F., Flachsbart, F., Rose, G., Viktorin, A., Fischer, K., Nygaard, M., Cordell, H. J., Crocco, P., Van Den Akker, E. B., Böhringer, S. & 67 others, Helmer, Q., Nelson, C. P., Saunders, G. I., Alver, M., Andersen-Ranberg, K., Breen, M. E., van Der Breggen, R., Caliebe, A., Capri, M., Cevenini, E., Collerton, J. C., Dato, S., Davies, K., Ford, I., Gampe, J., Garagnani, P., de Geus, E. J. C., Harrow, J., Van Heemst, D., Heijmans, B. T., Heinsen, F. A., Hottenga, J. J., Hofman, A., Jeune, B., Jonsson, P. V., Lathrop, M., Lechner, D., Martin-Ruiz, C., Mcnerlan, S. E., Mihailov, E., Montesanto, A., Mooijaart, S. P., Murphy, A., Nohr, E. A., Paternoster, L., Postmus, I., Rivadeneira, F., Ross, O. A., Salvioli, S., Sattar, N., Schreiber, S., Stefánsson, H., Stott, D. J., Tiemeier, H., Uitterlinden, A. G., Westendorp, R. G. J., Willemsen, G., Samani, N. J., Galan, P., Sørensen, T. I. A., Boomsma, D. I., Wouter Jukema, J., Rea, I. M., Passarino, G., de Craen, A. J. M., Christensen, K., Nebel, A., Stefánsson, K., Metspalu, A., Magnusson, P., Blanché, H., Christiansen, L., Kirkwood, T. B. L., Van Duijn, C. M., Franceschi, C., Houwing-Duistermaat, J. J. & Slagboom, P. E., 2014, In : Human Molecular Genetics. 23, 16, p. 4420-4432 13 p., ddu139.

Research output: Contribution to journalArticle

Genome-wide DNA methylation analysis in blood cells from patients with Werner syndrome

Guastafierro, T., Bacalini, M. G., Marcoccia, A., Gentilini, D., Pisoni, S., Di Blasio, A. M., Corsi, A., Franceschi, C., Raimondo, D., Spanò, A., Garagnani, P. & Bondanini, F., Aug 30 2017, In : Clinical Epigenetics. 9, 1, 92.

Research output: Contribution to journalArticle

Genome-wide linkage analysis for human longevity: Genetics of healthy aging study

Beekman, M., Blanché, H., Perola, M., Hervonen, A., Bezrukov, V., Sikora, E., Flachsbart, F., Christiansen, L., De Craen, A. J. M., Kirkwood, T. B. L., Rea, I. M., Poulain, M., Robine, J. M., Valensin, S., Stazi, M. A., Passarino, G., Deiana, L., Gonos, E. S., Paternoster, L., Sørensen, T. I. A. & 20 others, Tan, Q., Helmer, Q., Van Den Akker, E. B., Deelen, J., Martella, F., Cordell, H. J., Ayers, K. L., Vaupel, J. W., Törnwall, O., Johnson, T. E., Schreiber, S., Lathrop, M., Skytthe, A., Westendorp, R. G. J., Christensen, K., Gampe, J., Nebel, A., Houwing-Duistermaat, J. J., Slagboom, P. E. & Franceschi, C., 2013, In : Aging Cell. 12, 2, p. 184-193 10 p.

Research output: Contribution to journalArticle

Genome-Wide Scan Informed by Age-Related Disease Identifies Loci for Exceptional Human Longevity

Fortney, K., Dobriban, E., Garagnani, P., Pirazzini, C., Monti, D., Mari, D., Atzmon, G., Barzilai, N., Franceschi, C., Owen, A. B. & Kim, S. K., 2015, In : PLoS Genetics. 11, 12, e1005728.

Research output: Contribution to journalArticle

Genomic instability: A challenge for aging research

Franceschi, C., 1990, In : Aging clinical and experimental research. 2, 2, p. 101-104 4 p.

Research output: Contribution to journalArticle

Genomic instability and aging studies in centenarians (successful aging) and in patients with Down's syndrome (accelerated aging)

Franceschi, C., Monti, D., Scarfi, M. R., Zeni, O., Temperani, P., Emilia, G., Sansoni, P., Lio, M. B., Troiano, L., Agnesini, C., Salvioli, S. & Cossarlzza, A., 1992, In : Annals of the New York Academy of Sciences. 663, p. 4-16 13 p.

Research output: Contribution to journalArticle

Genomics and epigenomics

Garagnani, P., Terlizzi, R., Cevoli, S., Capellari, S., Pierangeli, G., Pirazzini, C., Bacalini, M. G., Franceschi, C. & Cortelli, P., Dec 1 2015, In : Journal of Headache and Pain. 16, p. 1 1 p., A7.

Research output: Contribution to journalArticle

Genomic stability, anti-inflammatory phenotype, and up-regulation of the RNAseH2 in cells from centenarians

Storci, G., De Carolis, S., Papi, A., Bacalini, M. G., Gensous, N., Marasco, E., Tesei, A., Fabbri, F., Arienti, C., Zanoni, M., Sarnelli, A., Santi, S., Olivieri, F., Mensà, E., Latini, S., Ferracin, M., Salvioli, S., Garagnani, P., Franceschi, C. & Bonafè, M., 2019, In : Cell Death and Differentiation. 26, 9, p. 1845-1858 14 p.

Research output: Contribution to journalArticle

Genomic stability, anti-inflammatory phenotype, and up-regulation of the RNAseH2 in cells from centenarians

Storci, G., De Carolis, S., Papi, A., Bacalini, M. G., Gensous, N., Marasco, E., Tesei, A., Fabbri, F., Arienti, C., Zanoni, M., Sarnelli, A., Santi, S., Olivieri, F., Mensà, E., Latini, S., Ferracin, M., Salvioli, S., Garagnani, P., Franceschi, C. & Bonafè, M., 2019, In : Cell Death and Differentiation. 26, 9, p. 1845-1858 14 p.

Research output: Contribution to journalArticle

Genomic stability, anti-inflammatory phenotype, and up-regulation of the RNAseH2 in cells from centenarians

Storci, G., De Carolis, S., Papi, A., Bacalini, M. G., Gensous, N., Marasco, E., Tesei, A., Fabbri, F., Arienti, C., Zanoni, M., Sarnelli, A., Santi, S., Olivieri, F., Mensà, E., Latini, S., Ferracin, M., Salvioli, S., Garagnani, P., Franceschi, C. & Bonafè, M., Sep 2019, In : Cell Death and Differentiation. 26, 9, p. 1845-1858 14 p.

Research output: Contribution to journalArticle

Genotype of inflammatory cytokines in limbal stem cell graft in Italian patients

Lescai, F., Conti, L., Bartolozzi, M., Ramazzotti, G., Mazzi, M., Sarnicola, V. & Franceschi, C., Jun 24 2005, In : Biochemical and Biophysical Research Communications. 332, 1, p. 95-100 6 p.

Research output: Contribution to journalArticle

Geroscience: Linking aging to chronic disease

Kennedy, B. K., Berger, S. L., Brunet, A., Campisi, J., Cuervo, A. M., Epel, E. S., Franceschi, C., Lithgow, G. J., Morimoto, R. I., Pessin, J. E., Rando, T. A., Richardson, A., Schadt, E. E., Wyss-Coray, T. & Sierra, F., Nov 6 2014, In : Cell. 159, 4, p. 709-713 5 p.

Research output: Contribution to journalArticle

Growth properties and growth factor responsiveness in skin fibroblasts from centenarians

Tesco, G., Vergelli, M., Grassilli, E., Salomoni, P., Bellesia, E., Sikora, E., Radziszewska, E., Barbieri, D., Latorraca, S., Fagiolo, U., Santacaterina, S., Amaducci, L., Tiozzo, R., Franceschi, C. & Sorbi, S., Mar 27 1998, In : Biochemical and Biophysical Research Communications. 244, 3, p. 912-916 5 p.

Research output: Contribution to journalArticle

Gut microbiome in down syndrome

Biagi, E., Cela, M., Centanni, M., Consoli, C., Rampelli, S., Turroni, S., Severgnini, M., Peano, C., Ghezzo, A., Scurti, M., Salvioli, S., Franceschi, C. & Brigidi, P., Nov 11 2014, In : PLoS One. 9, 11, e112023.

Research output: Contribution to journalArticle

Gut Microbiota and Extreme Longevity

Biagi, E., Franceschi, C., Rampelli, S., Severgnini, M., Ostan, R., Turroni, S., Consolandi, C., Quercia, S., Scurti, M., Monti, D., Capri, M., Brigidi, P. & Candela, M., Feb 24 2016, (Accepted/In press) In : Current Biology.

Research output: Contribution to journalArticle

Gut microbiota as a candidate for lifespan extension: An ecological/evolutionary perspective targeted on living organisms as metaorganisms

Ottaviani, E., Ventura, N., Mandrioli, M., Candela, M., Franchini, A. & Franceschi, C., Dec 2011, In : Biogerontology. 12, 6, p. 599-609 11 p.

Research output: Contribution to journalArticle

Gut neuroendocrine cells: Relationship to the proliferative activity and apoptosis of mucous epitheliocytes in aging

Kvetnoy, I., Popuichiev, V., Mikhina, L., Anisimov, V., Yuzhakov, V., Konovalov, S., Pogudina, N., Franceschi, C., Piantanelli, L., Rossolini, G., Zaia, A., Kvetnaia, T., Hernandez-Yago, J. & Blesa, J. R., 2001, In : Neuroendocrinology Letters. 22, 5, p. 337-341 5 p.

Research output: Contribution to journalArticle

Haemagglutinating activity of modeccin

Gasperi-Campani, A., Franceschi, C., Perino, G. & Stirpe, F., Aug 1979, In : Experientia. 35, 8, p. 1086-1087 2 p.

Research output: Contribution to journalArticle

HAPLOFIND: A new method for high-throughput mtDNA haplogroup assignment

Vianello, D., Sevini, F., Castellani, G., Lomartire, L., Capri, M. & Franceschi, C., Sep 2013, In : Human Mutation. 34, 9, p. 1189-1194 6 p.

Research output: Contribution to journalArticle

Have the oldest old adults ever been frail in the past? A hypothesis that explains modern trends in survival

Yashin, A. I., Ukraintseva, S. V., De Benedictis, G., Anisimov, V. N., Butov, A. A., Arbeev, K., Jdanov, D. A., Boiko, S. I., Begun, A. S., Bonafe, M. & Franceschi, C., 2001, In : Journals of Gerontology - Series A Biological Sciences and Medical Sciences. 56, 10

Research output: Contribution to journalArticle

Health status and 6 years survival of 552 90+ Italian sib-ships recruited within the EU Project GEHA (GEnetics of Healthy Ageing)

Cevenini, E., Cotichini, R., Stazi, M. A., Toccaceli, V., Palmas, M. G., Capri, M., De Rango, F., Dato, S., Passarino, G., Jeune, B. & Franceschi, C., 2014, In : Age. 36, 2, p. 949-966 18 p.

Research output: Contribution to journalArticle

Heat shock response by EBV-immortalized B-lymphocytes from centenarians and control subjects: A model to study the relevance of stress response in longevity

Marini, M., Lapalombella, R., Canaider, S., Farina, A., Monti, D., De Vescovi, V., Morellini, M., Bellizzi, D., Dato, S., De Benedictis, G., Passarino, G., Moresi, R., Tesei, S. & Franceschi, C., Jan 2004, In : Experimental Gerontology. 39, 1, p. 83-90 8 p.

Research output: Contribution to journalArticle

Helper activity of histocompatibility antigens on cell-mediated immunity.

Di Marco, A. T., Franceschi, C. & Prodi, G., Jun 1972, In : European Journal of Immunology. 2, 3, p. 240-242 3 p.

Research output: Contribution to journalArticle

Hemopoiesis in healthy old people and centenarians: Well-maintained responsiveness of CD34+ cells to hemopoietic growth factors and remodeling of cytokine network

Bagnara, G. P., Bonsi, L., Strippoli, P., Bonifazi, F., Tonelli, R., D'Addato, S., Paganelli, R., Scala, E., Fagiolo, U., Monti, D., Cossarizza, A., Bonafé, M. & Franceschi, C., Feb 2000, In : Journals of Gerontology - Series A Biological Sciences and Medical Sciences. 55, 2

Research output: Contribution to journalArticle

Heterogeneity of Thyroid Function and Impact of Peripheral Thyroxine Deiodination in Centenarians and Semi-Supercentenarians: Association With Functional Status and Mortality

Ostan, R., Monti, D., Mari, D., Arosio, B., Gentilini, D., Ferri, E., Passarino, G., De Rango, F., D'Aquila, P., Mariotti, S., Pasquali, R., Fanelli, F., Bucci, L., Franceschi, C. & Vitale, G., May 16 2019, In : The journals of gerontology. Series A, Biological sciences and medical sciences. 74, 6, p. 802-810 9 p.

Research output: Contribution to journalArticle

Open Access

Heterogeneity of thyroid function and impact of peripheralthyroxine deiodination in centenarians and semi-supercentenarians: Association with functional status and mortality

Ostan, R., Monti, D., Mari, D., Arosio, B., Gentilini, D., Ferri, E., Passarino, G., De Rango, F., D’Aquila, P., Mariotti, S., Pasquali, R., Fanelli, F., Bucci, L., Franceschi, C. & Vitale, G., 2019, In : Journals of Gerontology - Series A Biological Sciences and Medical Sciences. 74, 6, p. 802-810 9 p.

Research output: Contribution to journalArticle

High-resolution quantitative metabolome analysis of urine by automated flow injection NMR

Da Silva, L., Godejohann, M., Martin, F. P. J., Collino, S., Bürkle, A., Moreno-Villanueva, M., Bernhardt, J., Toussaint, O., Grubeck-Loebenstein, B., Gonos, E. S., Sikora, E., Grune, T., Breusing, N., Franceschi, C., Hervonen, A., Spraul, M. & Moco, S., Jun 18 2013, In : Analytical Chemistry. 85, 12, p. 5801-5809 9 p.

Research output: Contribution to journalArticle

HLA, aging, and longevity: A critical reappraisal

Caruso, C., Candore, G., Colonna Romano, G., Lio, D., Bonafè, M., Valensin, S. & Franceschi, C., 2000, In : Human Immunology. 61, 9, p. 942-949 8 p.

Research output: Contribution to journalArticle

HLA antigens and aging

Morellini, M., Trabace, S., Lulli, P., Cappellacci, S., Brioli, G., Orru, D., Pennesi, G., Monti, D., Cossarizza, A., Lambert-Gardini, S., Sansoni, P. & Franceschi, C., 1992, In : Annals of the New York Academy of Sciences. 663, p. 499-500 2 p.

Research output: Contribution to journalArticle