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Invariant NKT cells contribute to chronic lymphocytic leukemia surveillance and prognosis

Gorini, F., Azzimonti, L., Delfanti, G., Scarfò, L., Scielzo, C., Bertilaccio, MT., Ranghetti, P., Gulino, A., Doglioni, C., Di Napoli, A., Capri, M., Franceschi, C., Caligaris-Cappio, F., Ghia, P., Bellone, M., Dellabona, P., Casorati, G. & De Lalla, C., 2017, In : Blood. 129, 26, p. 3440-3451 12 p.

Research output: Contribution to journalArticle

Invecchiamento, infiammazione sistemica e malattie croniche complesse

Translated title of the contribution: Aging, systemic inflammation and complex chronic diseasesFranceschi, C., Pauletto, P., Incalzi, R. A. & Fabbri, L. M., Mar 2011, In : Italian Journal of Medicine. 5, 1 SUPPL. 1

Research output: Contribution to journalArticle

Invertebrate and Vertebrate Immune Cells Express Pro-opiomelanocortin (POMC) mRNA

Ottaviani, E., Capriglione, T. & Franceschi, C., Mar 1995, In : Brain, Behavior, and Immunity. 9, 1, p. 1-8 8 p.

Research output: Contribution to journalArticle

In vitro exposure of human lymphocytes to 900 MHz CW and GSM modulated radio-frequency: Studies of proliferation, apoptosis and mitochondrial membrane potential

Capri, M., Scarcella, E., Fumelli, C., Bianchi, E., Salvioli, S., Mesirca, P., Agostini, C., Antolini, A., Schiavoni, A., Castellani, G., Bersani, F. & Franceschi, C., Aug 2004, In : Radiation Research. 162, 2, p. 211-218 8 p.

Research output: Contribution to journalArticle

In vitro hypersensitivity to oxygen of Fanconi Anemia (FA) cells is linked to ex vivo evidence for oxidative stress in fa homozygotes and heterozygotes [2]

Pagano, G., Korkina, L. G., Del Principe, D., Lindau-Shepard, B., Zatterale, A. & Franceschi, C., 1997, In : Blood. 89, 3, p. 1111-1112 2 p.

Research output: Contribution to journalArticle

In vitro IL-6 production by EBV-immortalized B lymphocytes from young and elderly people genotyped for -174 C/G polymorphism in IL-6 gene: A model to study the genetic basis of inflamm-aging

Olivieri, F., Bonafè, M., Giovagnetti, S., Stecconi, R., Cardelli, M., Cavallone, L., Spazzafumo, L., Marchegiani, F., Carrieri, G., Mugianesi, E., Giampieri, C., Centurelli, M., Moresi, R., Tesei, S., Lisa, R., Viticchi, C., Falsetti, L., Salvioli, S. & Franceschi, C., Apr 1 2003, In : Mechanisms of Ageing and Development. 124, 4, p. 549-553 5 p.

Research output: Contribution to journalArticle

In vitro peroxidase oxidation induces stable dimers of β-amyloid (1- 42) through dityrosine bridge formation

Galeazzi, L., Ronchi, P., Franceschi, C. & Giunta, S., 1999, In : Amyloid. 6, 1, p. 7-13 7 p.

Research output: Contribution to journalArticle

In vivo accumulation of sulfated glycoprotein 2 mRNA in rat thymocytes upon dexamethasone-induced cell death

Bettuzzi, S., Troiano, L., Davalli, P., Tropea, F., Ingletti, M. C., Grassilli, E., Monti, D., Corti, A. & Franceschi, C., Mar 29 1991, In : Biochemical and Biophysical Research Communications. 175, 3, p. 810-815 6 p.

Research output: Contribution to journalArticle

Involvement of CD45 in dexamethasone- and heat shock-induced apoptosis of rat thymocytes

Troiano, L., Monti, D., Cossarizza, A., Lovato, E., Tropea, F., Barbieri, D., Morale, M. C., Gallo, F., Marchetti, B. & Franceschi, C., 1995, In : Biochemical and Biophysical Research Communications. 214, 3, p. 941-948 8 p.

Research output: Contribution to journalArticle

Involvement of Ets transcription factors and targets in osteoblast differentiation and matrix mineralization

Vary, C. P. H., Li, V., Raouf, A., Kitching, R., Kola, I., Franceschi, C., Venanzoni, M. & Seth, A., May 25 2000, In : Experimental Cell Research. 257, 1, p. 213-222 10 p.

Research output: Contribution to journalArticle

Involvement of ornithine decarboxylase and polyamines in glucocorticoid- induced apoptosis of rat thymocytes

Desiderio, M. A., Grassilli, E., Bellesia, E., Salomoni, P. & Franceschi, C., 1995, In : Cell Growth and Differentiation. 6, 5, p. 505-513 9 p.

Research output: Contribution to journalArticle

Is aging as complex as it would appear? New perspectives in aging research

Kirkwood, T. B. L. & Franceschi, C., 1992, In : Annals of the New York Academy of Sciences. 663, p. 412-417 6 p.

Research output: Contribution to journalArticle

Is chronic inflammation a determinant of blood pressure in the elderly?

Barbieri, M., Ferrucci, L., Corsi, A. M., Macchi, C., Lauretani, F., Bonafè, M., Olivieri, F., Giovagnetti, S., Franceschi, C. & Paolisso, G., Jul 1 2003, In : American Journal of Hypertension. 16, 7, p. 537-543 7 p.

Research output: Contribution to journalArticle

Is polyamine decrease a common feature of apoptosis? Evidence from γ rays- and heat shock-induced cell death

Grassill, E., Desiderio, M. A., Bellesia, E., Salomoni, P., Benatti, F. & Franceschi, C., 1995, In : Biochemical and Biophysical Research Communications. 216, 2, p. 708-714 7 p.

Research output: Contribution to journalArticle

Karyotype instability and anchorage-independent growth in telomerase-immortalized fibroblasts from two centenarian individuals

Mondello, C., Chiesa, M., Rebuzzini, P., Zongaro, S., Verri, A., Colombo, T., Giulotto, E., D'Incalci, M., Franceschi, C. & Nuzzo, F., Sep 5 2003, In : Biochemical and Biophysical Research Communications. 308, 4, p. 914-921 8 p.

Research output: Contribution to journalArticle

Lack of chromosomal aberration and micronucleus induction in human lymphocytes exposed to pulsed magnetic fields

Scarfì, M. R., Lioi, M. B., Zeni, O., Franceschetti, G., Franceschi, C. & Bersani, F., Apr 15 1994, In : Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis. 306, 2, p. 129-133 5 p.

Research output: Contribution to journalArticle

Lack of selective Vβ deletion in CD4+ or CD8+ T lymphocytes and functional integrity of T-cell repertoire during acute HIV syndrome

Cossarizza, A., Ortolani, C., Mussini, C., Guaraldi, G., Mongiardo, N., Borghi, V., Barbieri, D., Bellesia, E., Franceschini, M. G., De Rienzo, B. & Franceschi, C., 1995, In : AIDS (London, England). 9, 6, p. 547-553 7 p.

Research output: Contribution to journalArticle

LAK activity is inducible in blood mononuclear cells from human fetus

Cossarizza, A., Monti, D., Dagna-Bricarelli, F., Montagnani, G. & Franceschi, C., 1990, In : Immunology Letters. 24, 2, p. 137-140 4 p.

Research output: Contribution to journalArticle

Lamins are rapamycin targets that impact human longevity: A study in centenarians

Lattanzi, G., Ortolani, M., Columbaro, M., Prencipe, S., Mattioli, E., Lanzarini, C., Maraldi, N. M., Cenni, V., Garagnani, P., Salvioli, S., Storci, G., Bonafè, M., Capanni, C. & Franceschi, C., Jan 1 2014, In : Journal of Cell Science. 127, 1, p. 147-157 11 p.

Research output: Contribution to journalArticle

La sindrome di Down. Un invecchiamento precoce del sistema immunitario.

Translated title of the contribution: Down's syndrome. Precocious aging of the immune systemBonetti, F., Licastro, F., Chiricolo, M. & Franceschi, C., Dec 1980, In : Recenti Progressi in Medicina. 69, 6, p. 679-709 31 p.

Research output: Contribution to journalArticle

Legame del 3' metil-P-dimetilaminoazobenzene al DNA in differenti organi e nel fegato rigenerante di ratto.

Translated title of the contribution: Binding of 3-methyl-P-dimethylaminoazobenzene to DNA in different organs and in regenerating rat liverProdi, G., Finzi, C. & Franceschi, C., Jan 15 1969, In : Bollettino della Societa Italiana di Biologia Sperimentale. 45, 1, p. 24-26 3 p.

Research output: Contribution to journalArticle

Leukocyte telomere length is associated with complications of Type 2 diabetes mellitus

Testa, R., Olivieri, F., Sirolla, C., Spazzafumo, L., Rippo, M. R., Marra, M., Bonfigli, A. R., Ceriello, A., Antonicelli, R., Franceschi, C., Castellucci, C., Testa, I. & Procopio, A. D., Nov 2011, In : Diabetic Medicine. 28, 11, p. 1388-1394 7 p.

Research output: Contribution to journalArticle

Levamisole and HBsAg positive chronic persistent hepatitis

Masi, M., Paolucci, P., Timoncini, G., Fantini, M. P., Leggieri, G., Chiodo, F. & Franceschi, C., 1978, In : Archives of Disease in Childhood. 53, 9, p. 764-765 2 p.

Research output: Contribution to journalArticle

Life expectancy in the immune recovery era: The evolving scenario of the HIV epidemic in northern Italy

Guaraldi, G., Cossarizza, A., Franceschi, C., Roverato, A., Vaccher, E., Tambussi, G., Garlassi, E., Menozzi, M., Mussini, C. & Monforte, A. D. A., 2014, In : Journal of Acquired Immune Deficiency Syndromes. 65, 2, p. 175-181 7 p.

Research output: Contribution to journalArticle

Lifelong maintenance of composition, function and cellular/subcellular distribution of proteasomes in human liver

Bellavista, E., Martucci, M., Vasuri, F., Santoro, A., Mishto, M., Kloss, A., Capizzi, E., Degiovanni, A., Lanzarini, C., Remondini, D., Dazzi, A., Pellegrini, S., Cescon, M., Capri, M., Salvioli, S., D'Errico-Grigioni, A., Dahlmann, B., Grazi, G. L. & Franceschi, C., Nov 1 2014, In : Mechanisms of Ageing and Development. 141-142, p. 26-34 9 p.

Research output: Contribution to journalArticle

Lipoprotein(a) and lipoprotein profile in healthy centenarians: A reappraisal of vascular risk factors

Baggio, G., Donazzan, S., Monti, D., Mari, D., Martini, S., Gabelli, C., Vestra, M. D., Previato, L., Guido, M., Pigozzo, S., Cortella, I., Crepaldi, G. & Franceschi, C., 1998, In : FASEB Journal. 12, 6, p. 433-437 5 p.

Research output: Contribution to journalArticle

LL-paraoxonase genotype is associated with a more severe degree of homeostasis model assessment IR in healthy subjects

Barbieri, M., Bonafè, M., Marfella, R., Ragno, E., Giugliano, D., Franceschi, C. & Paolisso, G., 2002, In : Journal of Clinical Endocrinology and Metabolism. 87, 1, p. 222-225 4 p.

Research output: Contribution to journalArticle

Longevity genes across species: Conservation versus evolvability

Salvioli, S., Tieri, P., Castellani, G., Capri, M., Barbi, C., Santoro, A., Altilia, S., Invidia, L., Pierini, M., Bellavista, E., Monti, D. & Franceschi, C., 2007, In : Invertebrate Survival Journal. 4, 2, p. 112-118 7 p.

Research output: Contribution to journalArticle

Long telomeres and well preserved proliferative vigor in cells from centenarians: A contribution to longevity?

Franceschi, C., Mondello, C., Bonafè, M., Valensin, S., Sansoni, P. & Sorbi, S., Apr 1999, In : Aging clinical and experimental research. 11, 2, p. 69-72 4 p.

Research output: Contribution to journalArticle

Long-term effects of vaccination on attentional performance

Nicoletti, R., Adolfo Porro, C., Brighetti, G., Monti, D., Pagnoni, G., Guido, M., Rubichi, S. & Franceschi, C., Sep 28 2004, In : Vaccine. 22, 29-30, p. 3877-3881 5 p.

Research output: Contribution to journalArticle

Long-term immune-endocrine effects of bereavement: Relationships with anxiety levels and mood

Gerra, G., Monti, D., Panerai, A. E., Sacerdote, P., Anderlini, R., Avanzini, P., Zaimovic, A., Brambilla, F. & Franceschi, C., Dec 1 2003, In : Psychiatry Research. 121, 2, p. 145-158 14 p.

Research output: Contribution to journalArticle

Long-term immunologic effects of thymectomy in patients with myasthenia gravis

Gerli, R., Paganelli, R., Cossarizza, A., Muscat, C., Piccolo, G., Barbieri, D., Mariotti, S., Monti, D., Bistoni, O., Raiola, E., Venanzi, F. M., Bertotto, A. & Franceschi, C., 1999, In : Journal of Allergy and Clinical Immunology. 103, 5 I, p. 865-872 8 p.

Research output: Contribution to journalArticle

Low circulating IGF-I bioactivity is associated with human longevity: Findings in centenarians' offspring

Vitale, G., Brugts, M. P., Ogliari, G., Castaldi, D., Fatti, L. M., Varewijck, A. J., Lamberts, S. W., Monti, D., Bucci, L., Cevenini, E., Cavagnini, F., Franceschi, C., Hofland, L. J., Mari, D. & Janssen, J. A. M. J. L., 2012, In : Aging. 4, 9, p. 580-589 10 p.

Research output: Contribution to journalArticle

Lower platelet count in healthy centenarians correlates with dispersion of the QT interval

Gangemi, S., Basile, G., Merendino, R. A., Balbo, C. L., Mento, A., Nicita-Mauro, V., Franceschi, C. & Romano, M., Apr 2004, In : Aging clinical and experimental research. 16, 2, p. 169-171 3 p.

Research output: Contribution to journalArticle

Low insulin resistance and preserved β-cell function contribute to human longevity but are not associated with TH-INS genes

Paolisso, G., Barbieri, M., Rizzo, M. R., Carella, C., Rotondi, M., Bonafè, M., Franceschi, C., Rose, G. & De Benedictis, G., 2001, In : Experimental Gerontology. 37, 1, p. 149-156 8 p.

Research output: Contribution to journalArticle

Low tobacco-related cancer incidence in offspring of long-lived siblings: A comparison with Danish national cancer registry data

Pedersen, J. K., Skytthe, A., McGue, M., Honig, L. S., Franceschi, C., Kirkwood, T. B. L., Passarino, G., Slagboom, P. E., Vaupel, J. W. & Christensen, K., Aug 1 2015, In : Annals of Epidemiology. 25, 8, p. 569-574 6 p.

Research output: Contribution to journalArticle

Low Vitamin D Status, High Bone Turnover, and Bone Fractures in Centenarians

Passeri, G., Pini, G., Troiano, L., Vescovini, R., Sansoni, P., Passeri, M., Gueresi, P., Delsignore, R., Pedrazzoni, M. & Franceschi, C., Nov 2003, In : Journal of Clinical Endocrinology and Metabolism. 88, 11, p. 5109-5115 7 p.

Research output: Contribution to journalArticle

Lymphocytes and low-frequency electromagnetic fields

Cadossi, R., Bersani, F., Cossarizza, A., Zucchini, P., Emilia, G., Torelli, G. & Franceschi, C., Jun 1992, In : FASEB Journal. 6, 9, p. 2667-2674 8 p.

Research output: Contribution to journalArticle

Lymphocyte subsets and natural killer cell activity in healthy old people and centenarians

Sansoni, P., Cossarizza, A., Brianti, V., Fagnoni, F., Snelli, G., Monti, D., Marcato, A., Passeri, G., Ortolani, C., Forti, E., Fagiolo, U., Passeri, M. & Franceschi, C., Nov 1 1993, In : Blood. 82, 9, p. 2767-2773 7 p.

Research output: Contribution to journalArticle

Male/female ratio in centenarians: A possible role played by population genetic structure

Passarino, G., Calignano, C., Vallone, A., Franceschi, C., Jeune, B., Robine, J. M., Yashin, A. I., Cavalli Sforza, L. L. & De Benedictis, G., Oct 2002, In : Experimental Gerontology. 37, 10-11, p. 1283-1289 7 p.

Research output: Contribution to journalArticle

MARK-AGE biomarkers of ageing

Bürkle, A., Moreno-Villanueva, M., Bernhard, J., Blasco, M., Zondag, G., Hoeijmakers, J. H. J., Toussaint, O., Grubeck-Loebenstein, B., Mocchegiani, E., Collino, S., Gonos, E. S., Sikora, E., Gradinaru, D., Dollé, M., Salmon, M., Kristensen, P., Griffiths, H. R., Libert, C., Grune, T., Breusing, N. & 10 others, Simm, A., Franceschi, C., Capri, M., Talbot, D., Caiafa, P., Friguet, B., Slagboom, P. E., Hervonen, A., Hurme, M. & Aspinall, R., Nov 1 2015, In : Mechanisms of Ageing and Development. 151, p. 2-12 11 p.

Research output: Contribution to journalArticle

MARK-AGE population: From the human model to new insights

Capri, M., Moreno-Villanueva, M., Cevenini, E., Pini, E., Scurti, M., Borelli, V., Palmas, M. G., Zoli, M., Schön, C., Siepelmeyer, A., Bernhardt, J., Fiegl, S., Zondag, G., de Craen, A. J. M., Hervonen, A., Hurme, M., Sikora, E., Gonos, E. S., Voutetakis, K., Toussaint, O. & 4 others, Debacq-Chainiaux, F., Grubeck-Loebenstein, B., Bürkle, A. & Franceschi, C., Nov 1 2015, In : Mechanisms of Ageing and Development. 151, p. 13-17 5 p.

Research output: Contribution to journalArticle

MARK-AGE standard operating procedures (SOPs): A successful effort

Moreno-Villanueva, M., Capri, M., Breusing, N., Siepelmeyer, A., Sevini, F., Ghezzo, A., de Craen, A. J. M., Hervonen, A., Hurme, M., Schön, C., Grune, T., Franceschi, C. & Bürkle, A., Nov 1 2015, In : Mechanisms of Ageing and Development. 151, p. 18-25 8 p.

Research output: Contribution to journalArticle

Marked increase with age of type 1 cytokines within memory and effector/cytotoxic CD8+ T cells in humans: A contribution to understand the relationship between inflammation and immunosenescence

Zanni, F., Vescovini, R., Biasini, C., Fagnoni, F., Zanlari, L., Telera, A., Di Pede, P., Passeri, G., Pedrazzoni, M., Passeri, M., Franceschi, C. & Sansoni, P., Sep 1 2003, In : Experimental Gerontology. 38, 9, p. 981-987 7 p.

Research output: Contribution to journalArticle

Markers of inflammation, Vitamin E and peripheral nervous system function. The InCHIANTI study

Di Iorio, A., Cherubini, A., Volpato, S., Sparvieri, E., Lauretani, F., Franceschi, C., Senin, U., Abate, G., Paganelli, R., Martin, A., Andres-Lacueva, C. & Ferrucci, L., Sep 2006, In : Neurobiology of Aging. 27, 9, p. 1280-1288 9 p.

Research output: Contribution to journalArticle

Massive activation of immune cells with an intact t cell repertoire in acute human immunodeficiency virus syndrome

Cossarizza, A., Ortolani, C., Mussini, C., Borghi, V., Guaraldi, G., Mongiardo, N., Bellesia, E., Franceschini, M. G., De Rienzo, B. & Franceschi, C., 1995, In : Journal of Infectious Diseases. 172, 1, p. 105-112 8 p.

Research output: Contribution to journalArticle

Massive load of functional effector CD4+ and CD8+ T cells against cytomegalovirus in very old subjects

Vescovini, R., Biasini, C., Fagnoni, F. F., Telera, A. R., Zanlari, L., Pedrazzoni, M., Bucci, L., Monti, D., Medici, M. C., Chezzi, C., Franceschi, C. & Sansoni, P., Sep 15 2007, In : Journal of Immunology. 179, 6, p. 4283-4291 9 p.

Research output: Contribution to journalArticle

Massive parallel sequencing of human whole mitochondrial genomes with Ion Torrent technology: an optimized workflow for Anthropological and Population Genetics studies

De Fanti, S., Vianello, D., Giuliani, C., Quagliariello, A., Cherubini, A., Sevini, F., Iaquilano, N., Franceschi, C., Sazzini, M. & Luiselli, D., Oct 31 2016, (Accepted/In press) In : Mitochondrial DNA Part A: DNA Mapping, Sequencing, and Analysis. p. 1-8 8 p.

Research output: Contribution to journalArticle