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Research Output 1969 2019

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Article
2016

Incidence of neuroepithelial primary brain tumors among adult population of Emilia-Romagna Region, Italy

Baldin, E., Testoni, S., de Pasqua, S., Ferro, S., Albani, F., Baruzzi, A., Dalessandro, R., Baruzzi, A., Albani, F., Calbucci, F., D’Alessandro, R., Michelucci, R., Brandes, A., Eusebi, V., Ceruti, S., Fainardi, E., Tamarozzi, R., Emiliani, E., Cavallo, M., Franceschi, E. & 124 others, Tosoni, A., Cavallo, M., Fiorica, F., Valentini, A., Depenni, R., Mucciarini, C., Crisi, G., Sasso, E., Biasini, C., Cavanna, L., Guidetti, D., Marcello, N., Pisanello, A., Cremonini, A., Guiducci, G., de Pasqua, S., Testoni, S., Agati, R., Ambrosetto, G., Bacci, A., Baldin, E., Baldrati, A., Barbieri, E., Bartolini, S., Bellavista, E., Bisulli, F., Bonora, E., Bunkheila, F., Carelli, V., Crisci, M., Dall’Occa, P., Ferro, S., Franceschi, C., Frezza, G., Grasso, V., Leonardi, M., Mostacci, B., Palandri, G., Pasini, E., Pastore Trossello, M., Poggi, R., Riguzzi, P., Rinaldi, R., Rizzi, S., Romeo, G., Spagnolli, F., Tinuper, P., Trocino, C., Dall'Agata, M., Faedi, M., Frattarelli, M., Gentili, G., Giovannini, A., Iorio, P., Pasquini, U., Galletti, G., Guidi, C., Neri, W., Patuelli, A., Strumia, S., Casmiro, M., Gamboni, A., Rasi, F., Cruciani, G., Cenni, P., Dazzi, C., Guidi, A. R., Zumaglini, F., Amadori, A., Pasini, G., Pasquinelli, M., Pasquini, E., Polselli, A., Ravasio, A., Viti, B., Sintini, M., Ariatti, A., Bertolini, F., Bigliardi, G., Carpeggiani, P., Cavalleri, F., Meletti, S., Nichelli, P., Pettorelli, E., Pinna, G., Zunarelli, E., Artioli, F., Bernardini, I., Costa, M., Greco, G., Guerzoni, R., Stucchi, C., Iaccarino, C., Ragazzi, M., Rizzi, R., Zuccoli, G., Api, P., Cartei, F., Fallica, E., Granieri, E., Latini, F., Lelli, G., Monetti, C., Saletti, A., Schivalocchi, R., Seraceni, S., Tola, M. R., Urbini, B., Giorgi, C., Montanari, E., Cerasti, D., Crafa, P., Dascola, I., Florindo, I., Giombelli, E., Mazza, S., Ramponi, V., Servadei, F., Silini, E. M., Torelli, P., Immovilli, P., Morelli, N., Vanzo, C. & Nobile, C., Nov 2 2016, (Accepted/In press) In : Neurological Sciences. p. 1-8 8 p.

Research output: Contribution to journalArticle

Brain Neoplasms
Italy
International Classification of Diseases
Incidence
Population

Incidence of neuroepithelial primary brain tumors among adult population of Emilia-Romagna Region, Italy

Baldin, E., Testoni, S., de Pasqua, S., Ferro, S., Albani, F., Baruzzi, A., Dalessandro, R., Baruzzi, A., Albani, F., Calbucci, F., D’Alessandro, R., Michelucci, R., Brandes, A., Eusebi, V., Ceruti, S., Fainardi, E., Tamarozzi, R., Emiliani, E., Cavallo, M., Franceschi, E. & 124 others, Tosoni, A., Cavallo, M., Fiorica, F., Valentini, A., Depenni, R., Mucciarini, C., Crisi, G., Sasso, E., Biasini, C., Cavanna, L., Guidetti, D., Marcello, N., Pisanello, A., Cremonini, A., Guiducci, G., de Pasqua, S., Testoni, S., Agati, R., Ambrosetto, G., Bacci, A., Baldin, E., Baldrati, A., Barbieri, E., Bartolini, S., Bellavista, E., Bisulli, F., Bonora, E., Bunkheila, F., Carelli, V., Crisci, M., Dall’Occa, P., Ferro, S., Franceschi, C., Frezza, G., Grasso, V., Leonardi, M., Mostacci, B., Palandri, G., Pasini, E., Pastore Trossello, M., Poggi, R., Riguzzi, P., Rinaldi, R., Rizzi, S., Romeo, G., Spagnolli, F., Tinuper, P., Trocino, C., Dall'Agata, M., Faedi, M., Frattarelli, M., Gentili, G., Giovannini, A., Iorio, P., Pasquini, U., Galletti, G., Guidi, C., Neri, W., Patuelli, A., Strumia, S., Casmiro, M., Gamboni, A., Rasi, F., Cruciani, G., Cenni, P., Dazzi, C., Guidi, A. R., Zumaglini, F., Amadori, A., Pasini, G., Pasquinelli, M., Pasquini, E., Polselli, A., Ravasio, A., Viti, B., Sintini, M., Ariatti, A., Bertolini, F., Bigliardi, G., Carpeggiani, P., Cavalleri, F., Meletti, S., Nichelli, P., Pettorelli, E., Pinna, G., Zunarelli, E., Artioli, F., Bernardini, I., Costa, M., Greco, G., Guerzoni, R., Stucchi, C., Iaccarino, C., Ragazzi, M., Rizzi, R., Zuccoli, G., Api, P., Cartei, F., Fallica, E., Granieri, E., Latini, F., Lelli, G., Monetti, C., Saletti, A., Schivalocchi, R., Seraceni, S., Tola, M. R., Urbini, B., Giorgi, C., Montanari, E., Cerasti, D., Crafa, P., Dascola, I., Florindo, I., Giombelli, E., Mazza, S., Ramponi, V., Servadei, F., Silini, E. M., Torelli, P., Immovilli, P., Morelli, N., Vanzo, C. & Nobile, C., Nov 2 2016, (Accepted/In press) In : Neurological Sciences. p. 1-8 8 p.

Research output: Contribution to journalArticle

Brain Neoplasms
Italy
International Classification of Diseases
Incidence
Population

Incidence of neuroepithelial primary brain tumors among adult population of Emilia-Romagna Region, Italy

Baldin, E., Testoni, S., de Pasqua, S., Ferro, S., Albani, F., Baruzzi, A., Dalessandro, R., Baruzzi, A., Albani, F., Calbucci, F., D’Alessandro, R., Michelucci, R., Brandes, A., Eusebi, V., Ceruti, S., Fainardi, E., Tamarozzi, R., Emiliani, E., Cavallo, M., Franceschi, E. & 124 others, Tosoni, A., Cavallo, M., Fiorica, F., Valentini, A., Depenni, R., Mucciarini, C., Crisi, G., Sasso, E., Biasini, C., Cavanna, L., Guidetti, D., Marcello, N., Pisanello, A., Cremonini, A., Guiducci, G., de Pasqua, S., Testoni, S., Agati, R., Ambrosetto, G., Bacci, A., Baldin, E., Baldrati, A., Barbieri, E., Bartolini, S., Bellavista, E., Bisulli, F., Bonora, E., Bunkheila, F., Carelli, V., Crisci, M., Dall’Occa, P., Ferro, S., Franceschi, C., Frezza, G., Grasso, V., Leonardi, M., Mostacci, B., Palandri, G., Pasini, E., Pastore Trossello, M., Poggi, R., Riguzzi, P., Rinaldi, R., Rizzi, S., Romeo, G., Spagnolli, F., Tinuper, P., Trocino, C., Dall'Agata, M., Faedi, M., Frattarelli, M., Gentili, G., Giovannini, A., Iorio, P., Pasquini, U., Galletti, G., Guidi, C., Neri, W., Patuelli, A., Strumia, S., Casmiro, M., Gamboni, A., Rasi, F., Cruciani, G., Cenni, P., Dazzi, C., Guidi, A. R., Zumaglini, F., Amadori, A., Pasini, G., Pasquinelli, M., Pasquini, E., Polselli, A., Ravasio, A., Viti, B., Sintini, M., Ariatti, A., Bertolini, F., Bigliardi, G., Carpeggiani, P., Cavalleri, F., Meletti, S., Nichelli, P., Pettorelli, E., Pinna, G., Zunarelli, E., Artioli, F., Bernardini, I., Costa, M., Greco, G., Guerzoni, R., Stucchi, C., Iaccarino, C., Ragazzi, M., Rizzi, R., Zuccoli, G., Api, P., Cartei, F., Fallica, E., Granieri, E., Latini, F., Lelli, G., Monetti, C., Saletti, A., Schivalocchi, R., Seraceni, S., Tola, M. R., Urbini, B., Giorgi, C., Montanari, E., Cerasti, D., Crafa, P., Dascola, I., Florindo, I., Giombelli, E., Mazza, S., Ramponi, V., Servadei, F., Silini, E. M., Torelli, P., Immovilli, P., Morelli, N., Vanzo, C. & Nobile, C., Nov 2 2016, (Accepted/In press) In : Neurological Sciences. p. 1-8 8 p.

Research output: Contribution to journalArticle

Brain Neoplasms
Italy
International Classification of Diseases
Incidence
Population
1 Citation (Scopus)

Incidence of neuroepithelial primary brain tumors among adult population of Emilia-Romagna Region, Italy

Baldin, E., Testoni, S., de Pasqua, S., Ferro, S., Albani, F., Baruzzi, A., D’Alessandro, R., Baruzzi, A., Albani, F., Calbucci, F., D’Alessandro, R., Michelucci, R., Brandes, A., Eusebi, V., Ceruti, S., Fainardi, E., Tamarozzi, R., Emiliani, E., Cavallo, M., Franceschi, E. & 31 others, Tosoni, A., Cavallo, M., Fiorica, F., Valentini, A., Depenni, R., Mucciarini, C., Crisi, G., Sasso, E., Biasini, C., Cavanna, L., Guidetti, D., Marcello, N., Pisanello, A., Cremonini, A. M., Guiducci, G., de Pasqua, S., Testoni, S., Agati, R., Ambrosetto, G., Bacci, A., Baldin, E., Baldrati, A., Barbieri, E., Bartolini, S., Bellavista, E., Bisulli, F., Franceschi, C., Mostacci, B., Riguzzi, P., Tinuper, P. & On behalf of PERNO study group, 2016, In : Neurological Sciences. p. 1-8 8 p.

Research output: Contribution to journalArticle

Brain Neoplasms
Italy
International Classification of Diseases
Incidence
Population
20 Citations (Scopus)

Inferring chronological age from DNA methylation patterns of human teeth

Giuliani, C., Cilli, E., Bacalini, M. G., Pirazzini, C., Sazzini, M., Gruppioni, G., Franceschi, C., Garagnani, P. & Luiselli, D., Apr 1 2016, In : American Journal of Physical Anthropology. 159, 4, p. 585-595 11 p.

Research output: Contribution to journalArticle

DNA Methylation
Tooth
Dental Cementum
Anthropology
DNA

Inflammaging and 'Garb-aging'

Franceschi, C., Garagnani, P., Vitale, G., Capri, M. & Salvioli, S., 2016, (Accepted/In press) In : Trends in Endocrinology and Metabolism.

Research output: Contribution to journalArticle

Garbage
Macrophages
Mitochondrial DNA
Mitochondrial Degradation
Inflammasomes
1 Citation (Scopus)

Massive parallel sequencing of human whole mitochondrial genomes with Ion Torrent technology: an optimized workflow for Anthropological and Population Genetics studies

De Fanti, S., Vianello, D., Giuliani, C., Quagliariello, A., Cherubini, A., Sevini, F., Iaquilano, N., Franceschi, C., Sazzini, M. & Luiselli, D., Oct 31 2016, (Accepted/In press) In : Mitochondrial DNA Part A: DNA Mapping, Sequencing, and Analysis. p. 1-8 8 p.

Research output: Contribution to journalArticle

Mitochondrial Genome
Anthropology
Workflow
Population Genetics
Ions
49 Citations (Scopus)

Novel loci and pathways significantly associated with longevity

Zeng, Y., Nie, C., Min, J., Liu, X., Li, M., Chen, H., Xu, H., Wang, M., Ni, T., Li, Y., Yan, H., Zhang, J. P., Song, C., Chi, L. Q., Wang, H. M., Dong, J., Zheng, G. Y., Lin, L., Qian, F., Qi, Y. & 37 others, Liu, X., Cao, H., Wang, Y., Zhang, L., Li, Z., Zhou, Y., Wang, Y., Lu, J., Li, J., Qi, M., Bolund, L., Yashin, A., Land, K. C., Gregory, S., Yang, Z., Gottschalk, W., Tao, W., Wang, J., Wang, J., Xu, X., Bae, H., Nygaard, M., Christiansen, L., Christensen, K., Franceschi, C., Lutz, M. W., Gu, J., Tan, Q., Perls, T., Sebastiani, P., Deelen, J., Slagboom, E., Hauser, E., Xu, H., Tian, X. L., Yang, H. & Vaupel, J. W., Feb 25 2016, In : Scientific Reports. 6, 21243.

Research output: Contribution to journalArticle

Calcium Signaling
Genome-Wide Association Study
Genome
Xenobiotics
Starch
18 Citations (Scopus)

Plasma Carotenoids, tocopherols, and retinol in the age-stratified (35-74 years) general population: A cross-sectional study in six European countries

Stuetz, W., Weber, D., Dollé, M. E. T., Jansen, E., Grubeck-Loebenstein, B., Fiegl, S., Toussaint, O., Bernhardt, J., Gonos, E. S., Franceschi, C., Sikora, E., Moreno-Villanueva, M., Breusing, N., Grune, T. & Bürkle, A., Oct 1 2016, In : Nutrients. 8, 10, 614.

Research output: Contribution to journalArticle

Tocopherols
Carotenoids
Vitamin A
tocopherols
cross-sectional studies
14 Citations (Scopus)

Suggestions from Geroscience for the Genetics of Age-Related Diseases

Franceschi, C. & Garagnani, P., Nov 1 2016, In : PLoS Genetics. 12, 11, e1006399.

Research output: Contribution to journalArticle

17 Citations (Scopus)

Systems medicine of inflammaging

Castellani, G. C., Menichetti, G., Garagnani, P., Bacalini, M. G., Pirazzini, C., Franceschi, C., Collino, S., Sala, C., Remondini, D., Giampieri, E., Mosca, E., Bersanelli, M., Vitali, S., Do Valle, I. F., Liò, P. & Milanesi, L., May 16 2016, In : Briefings in Bioinformatics. 17, 3, p. 527-540 14 p., bbv062.

Research output: Contribution to journalArticle

Systems Analysis
Medicine
Aging of materials
Physiological Phenomena
Phenotype
15 Citations (Scopus)

The emerging role of ECM crosslinking in T cell mobility as a hallmark of immunosenescence in humans

Moreau, J. F., Pradeu, T., Grignolio, A., Nardini, C., Castiglione, F., Tieri, P., Capri, M., Salvioli, S., Taupin, J. L., Garagnani, P. & Franceschi, C., Jun 1 2016, (Accepted/In press) In : Ageing Research Reviews.

Research output: Contribution to journalArticle

T-cells
Crosslinking
Extracellular Matrix
T-Lymphocytes
Aging of materials
2015
174 Citations (Scopus)

Accelerated epigenetic aging in Down syndrome

Horvath, S., Garagnani, P., Bacalini, M. G., Pirazzini, C., Salvioli, S., Gentilini, D., Di Blasio, A. M., Giuliani, C., Tung, S., Vinters, H. V. & Franceschi, C., Jun 1 2015, In : Aging Cell. 14, 3, p. 491-495 5 p.

Research output: Contribution to journalArticle

Down Syndrome
Epigenomics
Chronic Disease
Brain
2 Citations (Scopus)

Alpine Skiing With total knee ArthroPlasty (ASWAP): Impact on molecular and architectural features of musculo-skeletal ageing

Narici, M., Conte, M., Salvioli, S., Franceschi, C., Selby, A., Dela, F., Rieder, F., Kösters, A. & Müller, E., Aug 1 2015, In : Scandinavian Journal of Medicine and Science in Sports. 25, S2, p. 33-39 7 p.

Research output: Contribution to journalArticle

Skiing
Knee Replacement Arthroplasties
Sarcopenia
Neuromuscular Junction
Muscles
29 Citations (Scopus)

A meta-analysis on age-associated changes in blood DNA methylation: Results from an original analysis pipeline for Infinium 450k data

Bacalini, M. G., Boattini, A., Gentilini, D., Giampieri, E., Pirazzini, C., Giuliani, C., Fontanesi, E., Remondini, D., Capri, M., Rio, A. D., Luiselli, D., Vitale, G., Mari, D., Castellani, G., Di Blasio, A. M., Salvioli, S., Franceschi, C. & Garagnani, P., 2015, In : Aging. 7, 2, p. 97-109 13 p.

Research output: Contribution to journalArticle

DNA Methylation
Meta-Analysis
CpG Islands
Epigenomics
Genome
5 Citations (Scopus)

A patient with PMP22-related hereditary neuropathy and DBH-gene-related dysautonomia

Bartoletti-Stella, A., Chiaro, G., Calandra-Buonaura, G., Contin, M., Scaglione, C., Barletta, G., Cecere, A., Garagnani, P., Tieri, P., Ferrarini, A., Piras, S., Franceschi, C., Delledonne, M., Cortelli, P. & Capellari, S., Oct 1 2015, In : Journal of Neurology. 262, 10, p. 2373-2381 9 p.

Research output: Contribution to journalArticle

Primary Dysautonomias
Myelin Proteins
Gene Deletion
Genes
Exome
104 Citations (Scopus)

Decreased epigenetic age of PBMCs from Italian semi-supercentenarians and their offspring

Horvath, S., Pirazzini, C., Bacalini, M. G., Gentilini, D., Di Blasio, A. M., Delledonne, M., Mari, D., Arosio, B., Monti, D., Passarino, G., De Rango, F., D'Aquila, P., Giuliani, C., Marasco, E., Collino, S., Descombes, P., Garagnani, P. & Franceschi, C., 2015, In : Aging. 7, 12, p. 1159-1170 12 p.

Research output: Contribution to journalArticle

Epigenomics
Blood Cells
Genetic Epigenesis
Blood Cell Count
DNA Methylation
1 Citation (Scopus)

Demographic characteristics of sardinian centenarian genealogies: Preliminary results of the AKeA2 study

Lipsi, R. M., Caselli, G., Pozzi, L., Baggio, G., Carru, C., Franceschi, C., Vaupel, J. W. & Deiana, L., 2015, In : Demographic Research. 32, 1, p. 1049-1064 16 p.

Research output: Contribution to journalArticle

genealogy
descriptive statistics
12 Citations (Scopus)

Differential expression of perilipin 2 and 5 in human skeletal muscle during aging and their association with atrophy-related genes

Conte, M., Vasuri, F., Bertaggia, E., Armani, A., Santoro, A., Bellavista, E., Degiovanni, A., D’Errico-Grigioni, A., Trisolino, G., Capri, M., Franchi, M. V., Narici, M. V., Sandri, M., Franceschi, C. & Salvioli, S., Jan 6 2015, In : Biogerontology. 16, 3, p. 329-340 12 p.

Research output: Contribution to journalArticle

Atrophy
Skeletal Muscle
Sarcopenia
Lower Extremity
Muscular Atrophy

Erratum to: Differential expression of perilipin 2 and 5 in human skeletal muscle during aging and their association with atrophy-related genes(Biogerontology, (2015), DOI 10.1007/s10522-014-9549-5)

Conte, M., Vasuri, F., Bertaggia, E., Armani, A., Santoro, A., Bellavista, E., Degiovanni, A., D’Errico-Grigioni, A., Trisolino, G., Capri, M., Franchi, M. V., Narici, M. V., Sandri, M., Franceschi, C. & Salvioli, S., Feb 20 2015, In : Biogerontology. 16, 3, p. 341 1 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)

Fine dissection of human mitochondrial DNA haplogroup HV lineages reveals paleolithic signatures from European Glacial refugia

De Fanti, S., Barbieri, C., Sarno, S., Sevini, F., Vianello, D., Tamm, E., Metspalu, E., Van Oven, M., Hübner, A., Sazzini, M., Franceschi, C., Pettener, D. & Luiselli, D., Dec 1 2015, In : PLoS One. 10, 12, e0144391.

Research output: Contribution to journalArticle

Dissection
refuge habitats
Mitochondrial DNA
mitochondrial DNA
topology
53 Citations (Scopus)

Genome-Wide Scan Informed by Age-Related Disease Identifies Loci for Exceptional Human Longevity

Fortney, K., Dobriban, E., Garagnani, P., Pirazzini, C., Monti, D., Mari, D., Atzmon, G., Barzilai, N., Franceschi, C., Owen, A. B. & Kim, S. K., 2015, In : PLoS Genetics. 11, 12, e1005728.

Research output: Contribution to journalArticle

genome
Genome-Wide Association Study
Genome
loci
Single Nucleotide Polymorphism
1 Citation (Scopus)

Genomics and epigenomics

Garagnani, P., Terlizzi, R., Cevoli, S., Capellari, S., Pierangeli, G., Pirazzini, C., Bacalini, M. G., Franceschi, C. & Cortelli, P., Dec 1 2015, In : Journal of Headache and Pain. 16, p. 1 1 p., A7.

Research output: Contribution to journalArticle

45 Citations (Scopus)

Identification of a DNA methylation signature in blood cells from persons with down syndrome

Bacalini, M. G., Gentilini, D., Boattini, A., Giampieri, E., Pirazzini, C., Giuliani, C., Fontanesi, E., Scurti, M., Remondini, D., Capri, M., Cocchi, G., Ghezzo, A., Rio, A. D., Luiselli, D., Vitale, G., Mari, D., Castellani, G., Fraga, M., Di Blasio, A. M., Salvioli, S. & 2 others, Franceschi, C. & Garagnani, P., 2015, In : Aging. 7, 2, p. 82-96 15 p.

Research output: Contribution to journalArticle

DNA Methylation
Down Syndrome
Blood Cells
Premature Aging
Chromosomes, Human, Pair 21
6 Citations (Scopus)

Impact of diet and nutraceutical supplementation on inflammation in elderly people. Results from the RISTOMED study, an open-label randomized control trial

Ostan, R., Béné, M. C., Spazzafumo, L., Pinto, A., Donini, L. M., Pryen, F., Charrouf, Z., Valentini, L., Lochs, H., Bourdel-Marchasson, I., Blanc-Bisson, C., Buccolini, F., Brigidi, P., Franceschi, C. & D'Alessio, P. A., Feb 27 2015, (Accepted/In press) In : Clinical Nutrition.

Research output: Contribution to journalArticle

Dietary Supplements
Diet
Inflammation
Blood Sedimentation
Probiotics
36 Citations (Scopus)

Impact of personalized diet and probiotic supplementation on inflammation, nutritional parameters and intestinal microbiota - The "RISTOMED project": Randomized controlled trial in healthy older people

Valentini, L., Pinto, A., Bourdel-Marchasson, I., Ostan, R., Brigidi, P., Turroni, S., Hrelia, S., Hrelia, P., Bereswill, S., Fischer, A., Leoncini, E., Malaguti, M., Blanc-Bisson, C., Durrieu, J., Spazzafumo, L., Buccolini, F., Pryen, F., Donini, L. M., Franceschi, C. & Lochs, H., Aug 1 2015, In : Clinical Nutrition. 34, 4, p. 593-602 10 p.

Research output: Contribution to journalArticle

Probiotics
Oxidative Stress
Randomized Controlled Trials
Diet
Inflammation
7 Citations (Scopus)

Inferring the genetic history of lactase persistence along the Italian peninsula from a large genomic interval surrounding the LCT gene

De Fanti, S., Sazzini, M., Giuliani, C., Frazzoni, F., Sarno, S., Boattini, A., Marasco, E., Mantovani, V., Franceschi, C., Moral, P., Garagnani, P. & Luiselli, D., Dec 1 2015, In : American Journal of Physical Anthropology. 158, 4, p. 708-718 11 p.

Research output: Contribution to journalArticle

Lactase
persistence
History
Italy
history
70 Citations (Scopus)

Inflammaging and Cancer: A challenge for the mediterranean diet

Ostan, R., Lanzarini, C., Pini, E., Scurti, M., Vianello, D., Bertarelli, C., Fabbri, C., Izzi, M., Palmas, G., Biondi, F., Martucci, M., Bellavista, E., Salvioli, S., Capri, M., Franceschi, C. & Santoro, A., Apr 9 2015, In : Nutrients. 7, 4, p. 2589-2621 33 p.

Research output: Contribution to journalArticle

Mediterranean Diet
Mediterranean diet
neoplasms
Neoplasms
inflammation
224 Citations (Scopus)

Interventions to Slow Aging in Humans: Are We Ready?

Longo, V. D., Antebi, A., Bartke, A., Barzilai, N., Brown-Borg, H. M., Caruso, C., Curiel, T. J., de Cabo, R., Franceschi, C., Gems, D., Ingram, D. K., Johnson, T. E., Kennedy, B. K., Kenyon, C., Klein, S., Kopchick, J. J., Lepperdinger, G., Madeo, F., Mirisola, M. G., Mitchell, J. R. & 10 others, Passarino, G., Rudolph, K. L., Sedivy, J. M., Shadel, G. S., Sinclair, D. A., Spindler, S. R., Suh, Y., Vijg, J., Vinciguerra, M. & Fontana, L., 2015, (Accepted/In press) In : Aging Cell.

Research output: Contribution to journalArticle

Consensus
Pharmaceutical Preparations
Sirtuins
Education
AMP-Activated Protein Kinases
2 Citations (Scopus)

Low tobacco-related cancer incidence in offspring of long-lived siblings: A comparison with Danish national cancer registry data

Pedersen, J. K., Skytthe, A., McGue, M., Honig, L. S., Franceschi, C., Kirkwood, T. B. L., Passarino, G., Slagboom, P. E., Vaupel, J. W. & Christensen, K., Aug 1 2015, In : Annals of Epidemiology. 25, 8, p. 569-574 6 p.

Research output: Contribution to journalArticle

Tobacco
Registries
Incidence
Neoplasms
Cluster Analysis
92 Citations (Scopus)

MARK-AGE biomarkers of ageing

Bürkle, A., Moreno-Villanueva, M., Bernhard, J., Blasco, M., Zondag, G., Hoeijmakers, J. H. J., Toussaint, O., Grubeck-Loebenstein, B., Mocchegiani, E., Collino, S., Gonos, E. S., Sikora, E., Gradinaru, D., Dollé, M., Salmon, M., Kristensen, P., Griffiths, H. R., Libert, C., Grune, T., Breusing, N. & 10 others, Simm, A., Franceschi, C., Capri, M., Talbot, D., Caiafa, P., Friguet, B., Slagboom, P. E., Hervonen, A., Hurme, M. & Aspinall, R., Nov 1 2015, In : Mechanisms of Ageing and Development. 151, p. 2-12 11 p.

Research output: Contribution to journalArticle

Biomarkers
Literature
Cross-Sectional Studies
Population
15 Citations (Scopus)

MARK-AGE population: From the human model to new insights

Capri, M., Moreno-Villanueva, M., Cevenini, E., Pini, E., Scurti, M., Borelli, V., Palmas, M. G., Zoli, M., Schön, C., Siepelmeyer, A., Bernhardt, J., Fiegl, S., Zondag, G., de Craen, A. J. M., Hervonen, A., Hurme, M., Sikora, E., Gonos, E. S., Voutetakis, K., Toussaint, O. & 4 others, Debacq-Chainiaux, F., Grubeck-Loebenstein, B., Bürkle, A. & Franceschi, C., Nov 1 2015, In : Mechanisms of Ageing and Development. 151, p. 13-17 5 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)

MARK-AGE standard operating procedures (SOPs): A successful effort

Moreno-Villanueva, M., Capri, M., Breusing, N., Siepelmeyer, A., Sevini, F., Ghezzo, A., de Craen, A. J. M., Hervonen, A., Hurme, M., Schön, C., Grune, T., Franceschi, C. & Bürkle, A., Nov 1 2015, In : Mechanisms of Ageing and Development. 151, p. 18-25 8 p.

Research output: Contribution to journalArticle

Mouth Mucosa
Biomarkers
Urine
Research
Population
23 Citations (Scopus)

Metformin improves putative longevity effectors in peripheral mononuclear cells from subjects with prediabetes. A randomized controlled trial

Vigili de Kreutzenberg, S., Ceolotto, G., Cattelan, A., Pagnin, E., Mazzucato, M., Garagnani, P., Borelli, V., Bacalini, M. G., Franceschi, C., Fadini, G. P. & Avogaro, A., Jul 1 2015, In : Nutrition, Metabolism and Cardiovascular Diseases. 25, 7, p. 686-693 8 p.

Research output: Contribution to journalArticle

Prediabetic State
Metformin
Randomized Controlled Trials
Placebos
70-kDa Ribosomal Protein S6 Kinases
44 Citations (Scopus)

N-Glycomic changes in serum proteins in type 2 diabetes mellitus correlate with complications and with metabolic syndrome parameters

Testa, R., Vanhooren, V., Bonfigli, A. R., Boemi, M., Olivieri, F., Ceriello, A., Genovese, S., Spazzafumo, L., Borelli, V., Bacalini, M. G., Salvioli, S., Garagnani, P., Dewaele, S., Libert, C. & Franceschi, C., Mar 20 2015, In : PLoS One. 10, 3, e0119983.

Research output: Contribution to journalArticle

Glycomics
metabolic syndrome
Medical problems
Glycosylation
noninsulin-dependent diabetes mellitus
23 Citations (Scopus)

Plasma N-Glycome Signature of Down Syndrome

Borelli, V., Vanhooren, V., Lonardi, E., Reiding, K. R., Capri, M., Libert, C., Garagnani, P., Salvioli, S., Franceschi, C. & Wuhrer, M., Oct 2 2015, In : Journal of Proteome Research. 14, 10, p. 4232-4245 14 p.

Research output: Contribution to journalArticle

Down Syndrome
Aging of materials
Plasmas
Polysaccharides
Glycomics
8 Citations (Scopus)

Population-specific association of genes for telomere-associated proteins with longevity in an Italian population

Crocco, P., Barale, R., Rose, G., Rizzato, C., Santoro, A., De Rango, F., Carrai, M., Fogar, P., Monti, D., Biondi, F., Bucci, L., Ostan, R., Tallaro, F., Montesanto, A., Zambon, C. F., Franceschi, C., Canzian, F., Passarino, G. & Campa, D., Jun 15 2015, In : Biogerontology. 16, 3, p. 353-364 12 p.

Research output: Contribution to journalArticle

Telomere
Population
Genes
Leukocytes
Proteins
5 Citations (Scopus)

Quality control data of physiological and immunological biomarkers measured in serum and plasma

Jansen, E., Beekhof, P., Cremers, J., Weinberger, B., Fiegl, S., Toussaint, O., Bernhard, J., Gonos, E., Capri, M., Franceschi, C., Sikora, E., Moreno-Villanueva, M., Breusing, N., Grune, T., Bürkle, A. & Dollé, M. E. T., Jan 30 2015, In : Mechanisms of Ageing and Development. 151, p. 54-59 6 p.

Research output: Contribution to journalArticle

Quality Control
Biomarkers
Serum
Hemolysis
Hyperlipidemias
26 Citations (Scopus)

Quinazolinedione SIRT6 inhibitors sensitize cancer cells to chemotherapeutics

Sociali, G., Galeno, L., Parenti, M. D., Grozio, A., Bauer, I., Passalacqua, M., Boero, S., Donadini, A., Millo, E., Bellotti, M., Sturla, L., Damonte, P., Puddu, A., Ferroni, C., Varchi, G., Franceschi, C., Ballestrero, A., Poggi, A., Bruzzone, S., Nencioni, A. & 1 others, Del Rio, A., Aug 24 2015, In : European Journal of Medicinal Chemistry. 102, p. 530-539 10 p.

Research output: Contribution to journalArticle

Quinazolinones
gemcitabine
Cells
Acetylation
Oncology
99 Citations (Scopus)

Reconfiguration of DNA methylation in aging

Zampieri, M., Ciccarone, F., Calabrese, R., Franceschi, C., Bürkle, A. & Caiafa, P., Nov 1 2015, In : Mechanisms of Ageing and Development. 151, p. 60-70 11 p.

Research output: Contribution to journalArticle

DNA Methylation
Epigenomics
Genome
CpG Islands
DNA
18 Citations (Scopus)

Stochastic epigenetic mutations (DNA methylation) increase exponentially in human aging and correlate with X chromosome inactivation skewing in females

Gentilini, D., Garagnani, P., Pisoni, S., Bacalini, M. G., Calzari, L., Mari, D., Vitale, G., Franceschi, C. & Di Blasio, A. M., 2015, In : Aging. 7, 8, p. 568-578 11 p.

Research output: Contribution to journalArticle

X Chromosome Inactivation
DNA Methylation
Epigenomics
Mutation
Methylation
9 Citations (Scopus)

The adapter protein CD2AP binds to p53 protein in the cytoplasm and can discriminate its polymorphic variants P72R

Panni, S., Salvioli, S., Santonico, E., Langone, F., Storino, F., Altilia, S., Franceschi, C., Cesareni, G. & Castagnoli, L., Feb 1 2015, In : Journal of Biochemistry. 157, 2, p. 101-111 11 p.

Research output: Contribution to journalArticle

Proline
Cytoplasm
src Homology Domains
Proteins
Tumor Suppressor Protein p53
15 Citations (Scopus)

The epigenetic side of human adaptation: Hypotheses, evidences and theories

Giuliani, C., Bacalini, M. G., Sazzini, M., Pirazzini, C., Franceschi, C., Garagnani, P. & Luiselli, D., Jan 1 2015, In : Annals of Human Biology. 42, 1, p. 1-9 9 p.

Research output: Contribution to journalArticle

Epigenomics
DNA Methylation
Climate
Population
Diet
4 Citations (Scopus)

The use of non-variant sites to improve the clinical assessment of whole-genome sequence data

Ferrarini, A., Xumerle, L., Griggio, F., Garonzi, M., Cantaloni, C., Centomo, C., Vargas, S. M., Descombes, P., Marquis, J., Collino, S., Franceschi, C., Garagnani, P., Salisbury, B. A., Harvey, J. M. & Delledonne, M., Jul 6 2015, In : PLoS One. 10, 7, e0132180.

Research output: Contribution to journalArticle

Genes
Genome
genome
Exome
Alleles
8 Citations (Scopus)

Tracing Behçet's disease origins along the Silk Road: An anthropological evolutionary genetics perspective

Sazzini, M., Garagnani, P., Sarno, S., Fanti, S. D., Lazzano, T., Yao, D. Y., Boattini, A., Pazzola, G., Maramotti, S., Boiardi, L., Franceschi, C., Salvarani, C. & Luiselli, D., 2015, In : Clinical and Experimental Rheumatology. 33, p. 60-66 7 p.

Research output: Contribution to journalArticle

Silk
Anthropology
Inborn Genetic Diseases
Spatial Analysis
Vasculitis
2014
52 Citations (Scopus)

Age- and glycemia-related miR-126-3p levels in plasma and endothelial cells

Olivieri, F., Bonafè, M., Spazzafumo, L., Gobbi, M., Prattichizzo, F., Recchioni, R., Marcheselli, F., La Sala, L., Galeazzi, R., Rippo, M. R., Fulgenzi, G., Angelini, S., Lazzarini, R., Bonfigli, A. R., Brugè, F., Tiano, L., Genovese, S., Ceriello, A., Boemi, M., Franceschi, C. & 2 others, Procopio, A. D. & Testa, R., 2014, In : Aging. 6, 9, p. 771-787 17 p.

Research output: Contribution to journalArticle

Plasma Cells
Type 2 Diabetes Mellitus
Endothelial Cells
Healthy Volunteers
21 Citations (Scopus)

Ageing, longevity, exceptional longevity and related genetic and non genetics markers: Panel statement

Avery, P., Barzilai, N., Benetos, A., Bilianou, H., Capri, M., Caruso, C., Franceschi, C., Katsiki, N., Mikhailidis, D. P., Panotopoulos, G., Sikora, E., Tzanetakou, I. P. & Kolovou, G., 2014, In : Current Vascular Pharmacology. 12, 5, p. 659-661 3 p.

Research output: Contribution to journalArticle

30 Citations (Scopus)

Age-related changes of adaptive and neuropsychological features in persons with down syndrome

Ghezzo, A., Salvioli, S., Solimando, M. C., Palmieri, A., Chiostergi, C., Scurti, M., Lomartire, L., Bedetti, F., Cocchi, G., Follo, D., Pipitone, E., Rovatti, P., Zamberletti, J., Gomiero, T., Castellani, G. & Franceschi, C., Nov 24 2014, In : PLoS One. 9, 11, e113111.

Research output: Contribution to journalArticle

Down syndrome
Down Syndrome
Medical problems
Patient rehabilitation
Aging of materials
25 Citations (Scopus)

A parallel randomized trial on the effect of a healthful diet on inflammageing and its consequences in European elderly people: Design of the NU-AGE dietary intervention study

Berendsen, A., Santoro, A., Pini, E., Cevenini, E., Ostan, R., Pietruszka, B., Rolf, K., Cano, N., Caille, A., Lyon-Belgy, N., Fairweather-Tait, S., Feskens, E., Franceschi, C. & de Groot, C. P. G. M., 2014, In : Mechanisms of Ageing and Development. 134, 11-12, p. 523-530 8 p.

Research output: Contribution to journalArticle

Diet
Nutritional Requirements
Vitamin B 12
Vitamin D
C-Reactive Protein
943 Citations (Scopus)
Inflammation
National Institute on Aging (U.S.)
National Institutes of Health (U.S.)
Morbidity
Mortality