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2016

Centenarians' offspring as a model of healthy aging: a reappraisal of the data on Italian subjects and a comprehensive overview

Bucci, L., Ostan, R., Cevenini, E., Pini, E., Scurti, M., Vitale, G., Mari, D., Caruso, C., Sansoni, P., Fanelli, F., Pasquali, R., Gueresi, P., Franceschi, C. & Monti, D., Mar 2016, In : Aging. 8, 3, p. 510-9 10 p.

Research output: Contribution to journalArticle

Centenarians' offspring as a model of healthy aging: a reappraisal of the data on Italian subjects and a comprehensive overview

Bucci, L., Ostan, R., Cevenini, E., Pini, E., Scurti, M., Vitale, G., Mari, D., Caruso, C., Sansoni, P., Fanelli, F., Pasquali, R., Gueresi, P., Franceschi, C. & Monti, D., 2016, In : Aging. 8, 3, p. 510-519 10 p.

Research output: Contribution to journalArticle

Complex interplay between neutral and adaptive evolution shaped differential genomic background and disease susceptibility along the Italian peninsula

Sazzini, M., Gnecchi Ruscone, G. A., Giuliani, C., Sarno, S., Quagliariello, A., De Fanti, S., Boattini, A., Gentilini, D., Fiorito, G., Catanoso, M., Boiardi, L., Croci, S., Macchioni, P., Mantovani, V., Di Blasio, A. M., Matullo, G., Salvarani, C., Franceschi, C., Pettener, D., Garagnani, P. & 1 others, Luiselli, D., Sep 1 2016, In : Scientific Reports. 6, 32513.

Research output: Contribution to journalArticle

Complex interplay between neutral and adaptive evolution shaped differential genomic background and disease susceptibility along the Italian peninsula

Sazzini, M., Gnecchi Ruscone, G. A., Giuliani, C., Sarno, S., Quagliariello, A., De Fanti, S., Boattini, A., Gentilini, D., Fiorito, G., Catanoso, M. G., Boiardi, L., Croci, S., Macchioni, P., Mantovani, W., Di Blasio, A. M., Matullo, G., Salvarani, C., Franceschi, C., Pettener, D., Garagnani, P. & 1 others, Luiselli, D., Sep 1 2016, In : Scientific Reports. 6, 32513.

Research output: Contribution to journalArticle

Complex interplay between neutral and adaptive evolution shaped differential genomic background and disease susceptibility along the Italian peninsula

Sazzini, M., Gnecchi Ruscone, G. A., Giuliani, C., Sarno, S., Quagliariello, A., De Fanti, S., Boattini, A., Gentilini, D., Fiorito, G., Catanoso, M. G., Boiardi, L., Croci, S., Macchioni, P., Mantovani, W., Di Blasio, A. M., Matullo, G., Salvarani, C., Franceschi, C., Pettener, D., Garagnani, P. & 1 others, Luiselli, D., Sep 1 2016, In : Scientific Reports. 6, 32513.

Research output: Contribution to journalArticle

Corrigendum to "Immune parameters identify Italian centenarians with a longer five-year survival independent of their health and functional status" [Exp. Gerontol. 54C (2014) 14-20] DOI: 10.1016/j.exger.2014.01.023

Bucci, L., Ostan, R., Giampieri, E., Cevenini, E., Pini, E., Scurti, M., Vescovini, R., Sansoni, P., Caruso, C., Mari, D., Ronchetti, F., Borghi, M. O., Ogliari, G., Grossi, C., Capri, M., Salvioli, S., Castellani, G., Franceschi, C. & Monti, D., Jan 1 2016, In : Experimental Gerontology. 73, p. 121 1 p.

Research output: Contribution to journalArticle

Epigenetic variability across human populations: A Focus on DNA Methylation Profiles of the KRTCAP3, MAD1L1 and BRSK2 Genes

Giuliani, C., Sazzini, M., Bacalini, M. G., Pirazzini, C., Marasco, E., Fontanesi, E., Franceschi, C., Luiselli, D. & Garagnani, P., 2016, In : Genome Biology and Evolution. 8, 9, p. 2760-2773 14 p.

Research output: Contribution to journalArticle

Gender, aging and longevity in humans: an update of an intriguing/neglected scenario paving the way to a gender-specific medicine

Ostan, R., Monti, D., Gueresi, P., Bussolotto, M., Franceschi, C. & Baggio, G., Oct 1 2016, In : Clinical Science. 130, 19, p. 1711-25 15 p.

Research output: Contribution to journalArticle

Gut Microbiota and Extreme Longevity

Biagi, E., Franceschi, C., Rampelli, S., Severgnini, M., Ostan, R., Turroni, S., Consolandi, C., Quercia, S., Scurti, M., Monti, D., Capri, M., Brigidi, P. & Candela, M., Feb 24 2016, (Accepted/In press) In : Current Biology.

Research output: Contribution to journalArticle

Identification of novel plasma glycosylation-associated markers of aging

Catera, M., Borelli, V., Malagolini, N., Chiricolo, M., Venturi, G., Reis, C., Osoquot;rio, H., Abruzzo, P. M., Capri, M., Monti, D., Ostan, R., Franceschi, C. & Dall'Olio, F., 2016, In : Oncotarget. 7, 7, p. 7455-7468 14 p.

Research output: Contribution to journalArticle

Incidence of neuroepithelial primary brain tumors among adult population of Emilia-Romagna Region, Italy

Baldin, E., Testoni, S., de Pasqua, S., Ferro, S., Albani, F., Baruzzi, A., Dalessandro, R., Baruzzi, A., Albani, F., Calbucci, F., D’Alessandro, R., Michelucci, R., Brandes, A., Eusebi, V., Ceruti, S., Fainardi, E., Tamarozzi, R., Emiliani, E., Cavallo, M., Franceschi, E. & 124 others, Tosoni, A., Cavallo, M., Fiorica, F., Valentini, A., Depenni, R., Mucciarini, C., Crisi, G., Sasso, E., Biasini, C., Cavanna, L., Guidetti, D., Marcello, N., Pisanello, A., Cremonini, A., Guiducci, G., de Pasqua, S., Testoni, S., Agati, R., Ambrosetto, G., Bacci, A., Baldin, E., Baldrati, A., Barbieri, E., Bartolini, S., Bellavista, E., Bisulli, F., Bonora, E., Bunkheila, F., Carelli, V., Crisci, M., Dall’Occa, P., Ferro, S., Franceschi, C., Frezza, G., Grasso, V., Leonardi, M., Mostacci, B., Palandri, G., Pasini, E., Pastore Trossello, M., Poggi, R., Riguzzi, P., Rinaldi, R., Rizzi, S., Romeo, G., Spagnolli, F., Tinuper, P., Trocino, C., Dall'Agata, M., Faedi, M., Frattarelli, M., Gentili, G., Giovannini, A., Iorio, P., Pasquini, U., Galletti, G., Guidi, C., Neri, W., Patuelli, A., Strumia, S., Casmiro, M., Gamboni, A., Rasi, F., Cruciani, G., Cenni, P., Dazzi, C., Guidi, A. R., Zumaglini, F., Amadori, A., Pasini, G., Pasquinelli, M., Pasquini, E., Polselli, A., Ravasio, A., Viti, B., Sintini, M., Ariatti, A., Bertolini, F., Bigliardi, G., Carpeggiani, P., Cavalleri, F., Meletti, S., Nichelli, P., Pettorelli, E., Pinna, G., Zunarelli, E., Artioli, F., Bernardini, I., Costa, M., Greco, G., Guerzoni, R., Stucchi, C., Iaccarino, C., Ragazzi, M., Rizzi, R., Zuccoli, G., Api, P., Cartei, F., Fallica, E., Granieri, E., Latini, F., Lelli, G., Monetti, C., Saletti, A., Schivalocchi, R., Seraceni, S., Tola, M. R., Urbini, B., Giorgi, C., Montanari, E., Cerasti, D., Crafa, P., Dascola, I., Florindo, I., Giombelli, E., Mazza, S., Ramponi, V., Servadei, F., Silini, E. M., Torelli, P., Immovilli, P., Morelli, N., Vanzo, C. & Nobile, C., Nov 2 2016, (Accepted/In press) In : Neurological Sciences. p. 1-8 8 p.

Research output: Contribution to journalArticle

Incidence of neuroepithelial primary brain tumors among adult population of Emilia-Romagna Region, Italy

Baldin, E., Testoni, S., de Pasqua, S., Ferro, S., Albani, F., Baruzzi, A., Dalessandro, R., Baruzzi, A., Albani, F., Calbucci, F., D’Alessandro, R., Michelucci, R., Brandes, A., Eusebi, V., Ceruti, S., Fainardi, E., Tamarozzi, R., Emiliani, E., Cavallo, M., Franceschi, E. & 124 others, Tosoni, A., Cavallo, M., Fiorica, F., Valentini, A., Depenni, R., Mucciarini, C., Crisi, G., Sasso, E., Biasini, C., Cavanna, L., Guidetti, D., Marcello, N., Pisanello, A., Cremonini, A., Guiducci, G., de Pasqua, S., Testoni, S., Agati, R., Ambrosetto, G., Bacci, A., Baldin, E., Baldrati, A., Barbieri, E., Bartolini, S., Bellavista, E., Bisulli, F., Bonora, E., Bunkheila, F., Carelli, V., Crisci, M., Dall’Occa, P., Ferro, S., Franceschi, C., Frezza, G., Grasso, V., Leonardi, M., Mostacci, B., Palandri, G., Pasini, E., Pastore Trossello, M., Poggi, R., Riguzzi, P., Rinaldi, R., Rizzi, S., Romeo, G., Spagnolli, F., Tinuper, P., Trocino, C., Dall'Agata, M., Faedi, M., Frattarelli, M., Gentili, G., Giovannini, A., Iorio, P., Pasquini, U., Galletti, G., Guidi, C., Neri, W., Patuelli, A., Strumia, S., Casmiro, M., Gamboni, A., Rasi, F., Cruciani, G., Cenni, P., Dazzi, C., Guidi, A. R., Zumaglini, F., Amadori, A., Pasini, G., Pasquinelli, M., Pasquini, E., Polselli, A., Ravasio, A., Viti, B., Sintini, M., Ariatti, A., Bertolini, F., Bigliardi, G., Carpeggiani, P., Cavalleri, F., Meletti, S., Nichelli, P., Pettorelli, E., Pinna, G., Zunarelli, E., Artioli, F., Bernardini, I., Costa, M., Greco, G., Guerzoni, R., Stucchi, C., Iaccarino, C., Ragazzi, M., Rizzi, R., Zuccoli, G., Api, P., Cartei, F., Fallica, E., Granieri, E., Latini, F., Lelli, G., Monetti, C., Saletti, A., Schivalocchi, R., Seraceni, S., Tola, M. R., Urbini, B., Giorgi, C., Montanari, E., Cerasti, D., Crafa, P., Dascola, I., Florindo, I., Giombelli, E., Mazza, S., Ramponi, V., Servadei, F., Silini, E. M., Torelli, P., Immovilli, P., Morelli, N., Vanzo, C. & Nobile, C., Nov 2 2016, (Accepted/In press) In : Neurological Sciences. p. 1-8 8 p.

Research output: Contribution to journalArticle

Incidence of neuroepithelial primary brain tumors among adult population of Emilia-Romagna Region, Italy

Baldin, E., Testoni, S., de Pasqua, S., Ferro, S., Albani, F., Baruzzi, A., D’Alessandro, R., Baruzzi, A., Albani, F., Calbucci, F., D’Alessandro, R., Michelucci, R., Brandes, A., Eusebi, V., Ceruti, S., Fainardi, E., Tamarozzi, R., Emiliani, E., Cavallo, M., Franceschi, E. & 31 others, Tosoni, A., Cavallo, M., Fiorica, F., Valentini, A., Depenni, R., Mucciarini, C., Crisi, G., Sasso, E., Biasini, C., Cavanna, L., Guidetti, D., Marcello, N., Pisanello, A., Cremonini, A. M., Guiducci, G., de Pasqua, S., Testoni, S., Agati, R., Ambrosetto, G., Bacci, A., Baldin, E., Baldrati, A., Barbieri, E., Bartolini, S., Bellavista, E., Bisulli, F., Franceschi, C., Mostacci, B., Riguzzi, P., Tinuper, P. & On behalf of PERNO study group, 2016, In : Neurological Sciences. p. 1-8 8 p.

Research output: Contribution to journalArticle

Incidence of neuroepithelial primary brain tumors among adult population of Emilia-Romagna Region, Italy

Baldin, E., Testoni, S., de Pasqua, S., Ferro, S., Albani, F., Baruzzi, A., Dalessandro, R., Baruzzi, A., Albani, F., Calbucci, F., D’Alessandro, R., Michelucci, R., Brandes, A., Eusebi, V., Ceruti, S., Fainardi, E., Tamarozzi, R., Emiliani, E., Cavallo, M., Franceschi, E. & 124 others, Tosoni, A., Cavallo, M., Fiorica, F., Valentini, A., Depenni, R., Mucciarini, C., Crisi, G., Sasso, E., Biasini, C., Cavanna, L., Guidetti, D., Marcello, N., Pisanello, A., Cremonini, A., Guiducci, G., de Pasqua, S., Testoni, S., Agati, R., Ambrosetto, G., Bacci, A., Baldin, E., Baldrati, A., Barbieri, E., Bartolini, S., Bellavista, E., Bisulli, F., Bonora, E., Bunkheila, F., Carelli, V., Crisci, M., Dall’Occa, P., Ferro, S., Franceschi, C., Frezza, G., Grasso, V., Leonardi, M., Mostacci, B., Palandri, G., Pasini, E., Pastore Trossello, M., Poggi, R., Riguzzi, P., Rinaldi, R., Rizzi, S., Romeo, G., Spagnolli, F., Tinuper, P., Trocino, C., Dall'Agata, M., Faedi, M., Frattarelli, M., Gentili, G., Giovannini, A., Iorio, P., Pasquini, U., Galletti, G., Guidi, C., Neri, W., Patuelli, A., Strumia, S., Casmiro, M., Gamboni, A., Rasi, F., Cruciani, G., Cenni, P., Dazzi, C., Guidi, A. R., Zumaglini, F., Amadori, A., Pasini, G., Pasquinelli, M., Pasquini, E., Polselli, A., Ravasio, A., Viti, B., Sintini, M., Ariatti, A., Bertolini, F., Bigliardi, G., Carpeggiani, P., Cavalleri, F., Meletti, S., Nichelli, P., Pettorelli, E., Pinna, G., Zunarelli, E., Artioli, F., Bernardini, I., Costa, M., Greco, G., Guerzoni, R., Stucchi, C., Iaccarino, C., Ragazzi, M., Rizzi, R., Zuccoli, G., Api, P., Cartei, F., Fallica, E., Granieri, E., Latini, F., Lelli, G., Monetti, C., Saletti, A., Schivalocchi, R., Seraceni, S., Tola, M. R., Urbini, B., Giorgi, C., Montanari, E., Cerasti, D., Crafa, P., Dascola, I., Florindo, I., Giombelli, E., Mazza, S., Ramponi, V., Servadei, F., Silini, E. M., Torelli, P., Immovilli, P., Morelli, N., Vanzo, C. & Nobile, C., Nov 2 2016, (Accepted/In press) In : Neurological Sciences. p. 1-8 8 p.

Research output: Contribution to journalArticle

Inferring chronological age from DNA methylation patterns of human teeth

Giuliani, C., Cilli, E., Bacalini, M. G., Pirazzini, C., Sazzini, M., Gruppioni, G., Franceschi, C., Garagnani, P. & Luiselli, D., Apr 1 2016, In : American Journal of Physical Anthropology. 159, 4, p. 585-595 11 p.

Research output: Contribution to journalArticle

Inflammaging and 'Garb-aging'

Franceschi, C., Garagnani, P., Vitale, G., Capri, M. & Salvioli, S., 2016, (Accepted/In press) In : Trends in Endocrinology and Metabolism.

Research output: Contribution to journalArticle

Massive parallel sequencing of human whole mitochondrial genomes with Ion Torrent technology: an optimized workflow for Anthropological and Population Genetics studies

De Fanti, S., Vianello, D., Giuliani, C., Quagliariello, A., Cherubini, A., Sevini, F., Iaquilano, N., Franceschi, C., Sazzini, M. & Luiselli, D., Oct 31 2016, (Accepted/In press) In : Mitochondrial DNA Part A: DNA Mapping, Sequencing, and Analysis. p. 1-8 8 p.

Research output: Contribution to journalArticle

Novel loci and pathways significantly associated with longevity

Zeng, Y., Nie, C., Min, J., Liu, X., Li, M., Chen, H., Xu, H., Wang, M., Ni, T., Li, Y., Yan, H., Zhang, J. P., Song, C., Chi, L. Q., Wang, H. M., Dong, J., Zheng, G. Y., Lin, L., Qian, F., Qi, Y. & 37 others, Liu, X., Cao, H., Wang, Y., Zhang, L., Li, Z., Zhou, Y., Wang, Y., Lu, J., Li, J., Qi, M., Bolund, L., Yashin, A., Land, K. C., Gregory, S., Yang, Z., Gottschalk, W., Tao, W., Wang, J., Wang, J., Xu, X., Bae, H., Nygaard, M., Christiansen, L., Christensen, K., Franceschi, C., Lutz, M. W., Gu, J., Tan, Q., Perls, T., Sebastiani, P., Deelen, J., Slagboom, E., Hauser, E., Xu, H., Tian, X. L., Yang, H. & Vaupel, J. W., Feb 25 2016, In : Scientific Reports. 6, 21243.

Research output: Contribution to journalArticle

Plasma Carotenoids, tocopherols, and retinol in the age-stratified (35-74 years) general population: A cross-sectional study in six European countries

Stuetz, W., Weber, D., Dollé, M. E. T., Jansen, E., Grubeck-Loebenstein, B., Fiegl, S., Toussaint, O., Bernhardt, J., Gonos, E. S., Franceschi, C., Sikora, E., Moreno-Villanueva, M., Breusing, N., Grune, T. & Bürkle, A., Oct 1 2016, In : Nutrients. 8, 10, 614.

Research output: Contribution to journalArticle

Suggestions from Geroscience for the Genetics of Age-Related Diseases

Franceschi, C. & Garagnani, P., Nov 1 2016, In : PLoS Genetics. 12, 11, e1006399.

Research output: Contribution to journalArticle

Systems medicine of inflammaging

Castellani, G. C., Menichetti, G., Garagnani, P., Bacalini, M. G., Pirazzini, C., Franceschi, C., Collino, S., Sala, C., Remondini, D., Giampieri, E., Mosca, E., Bersanelli, M., Vitali, S., Do Valle, I. F., Liò, P. & Milanesi, L., May 16 2016, In : Briefings in Bioinformatics. 17, 3, p. 527-540 14 p., bbv062.

Research output: Contribution to journalArticle

The emerging role of ECM crosslinking in T cell mobility as a hallmark of immunosenescence in humans

Moreau, J. F., Pradeu, T., Grignolio, A., Nardini, C., Castiglione, F., Tieri, P., Capri, M., Salvioli, S., Taupin, J. L., Garagnani, P. & Franceschi, C., Jun 1 2016, (Accepted/In press) In : Ageing Research Reviews.

Research output: Contribution to journalArticle

2015

Accelerated epigenetic aging in Down syndrome

Horvath, S., Garagnani, P., Bacalini, M. G., Pirazzini, C., Salvioli, S., Gentilini, D., Di Blasio, A. M., Giuliani, C., Tung, S., Vinters, H. V. & Franceschi, C., Jun 1 2015, In : Aging Cell. 14, 3, p. 491-495 5 p.

Research output: Contribution to journalArticle

Alpine Skiing With total knee ArthroPlasty (ASWAP): Impact on molecular and architectural features of musculo-skeletal ageing

Narici, M., Conte, M., Salvioli, S., Franceschi, C., Selby, A., Dela, F., Rieder, F., Kösters, A. & Müller, E., Aug 1 2015, In : Scandinavian Journal of Medicine and Science in Sports. 25, S2, p. 33-39 7 p.

Research output: Contribution to journalArticle

A meta-analysis on age-associated changes in blood DNA methylation: Results from an original analysis pipeline for Infinium 450k data

Bacalini, M. G., Boattini, A., Gentilini, D., Giampieri, E., Pirazzini, C., Giuliani, C., Fontanesi, E., Remondini, D., Capri, M., Rio, A. D., Luiselli, D., Vitale, G., Mari, D., Castellani, G., Di Blasio, A. M., Salvioli, S., Franceschi, C. & Garagnani, P., 2015, In : Aging. 7, 2, p. 97-109 13 p.

Research output: Contribution to journalArticle

A patient with PMP22-related hereditary neuropathy and DBH-gene-related dysautonomia

Bartoletti-Stella, A., Chiaro, G., Calandra-Buonaura, G., Contin, M., Scaglione, C., Barletta, G., Cecere, A., Garagnani, P., Tieri, P., Ferrarini, A., Piras, S., Franceschi, C., Delledonne, M., Cortelli, P. & Capellari, S., Oct 1 2015, In : Journal of Neurology. 262, 10, p. 2373-2381 9 p.

Research output: Contribution to journalArticle

Decreased epigenetic age of PBMCs from Italian semi-supercentenarians and their offspring

Horvath, S., Pirazzini, C., Bacalini, M. G., Gentilini, D., Di Blasio, A. M., Delledonne, M., Mari, D., Arosio, B., Monti, D., Passarino, G., De Rango, F., D'Aquila, P., Giuliani, C., Marasco, E., Collino, S., Descombes, P., Garagnani, P. & Franceschi, C., 2015, In : Aging. 7, 12, p. 1159-1170 12 p.

Research output: Contribution to journalArticle

Demographic characteristics of sardinian centenarian genealogies: Preliminary results of the AKeA2 study

Lipsi, R. M., Caselli, G., Pozzi, L., Baggio, G., Carru, C., Franceschi, C., Vaupel, J. W. & Deiana, L., 2015, In : Demographic Research. 32, 1, p. 1049-1064 16 p.

Research output: Contribution to journalArticle

Differential expression of perilipin 2 and 5 in human skeletal muscle during aging and their association with atrophy-related genes

Conte, M., Vasuri, F., Bertaggia, E., Armani, A., Santoro, A., Bellavista, E., Degiovanni, A., D’Errico-Grigioni, A., Trisolino, G., Capri, M., Franchi, M. V., Narici, M. V., Sandri, M., Franceschi, C. & Salvioli, S., Jan 6 2015, In : Biogerontology. 16, 3, p. 329-340 12 p.

Research output: Contribution to journalArticle

Erratum to: Differential expression of perilipin 2 and 5 in human skeletal muscle during aging and their association with atrophy-related genes(Biogerontology, (2015), DOI 10.1007/s10522-014-9549-5)

Conte, M., Vasuri, F., Bertaggia, E., Armani, A., Santoro, A., Bellavista, E., Degiovanni, A., D’Errico-Grigioni, A., Trisolino, G., Capri, M., Franchi, M. V., Narici, M. V., Sandri, M., Franceschi, C. & Salvioli, S., Feb 20 2015, In : Biogerontology. 16, 3, p. 341 1 p.

Research output: Contribution to journalArticle

Fine dissection of human mitochondrial DNA haplogroup HV lineages reveals paleolithic signatures from European Glacial refugia

De Fanti, S., Barbieri, C., Sarno, S., Sevini, F., Vianello, D., Tamm, E., Metspalu, E., Van Oven, M., Hübner, A., Sazzini, M., Franceschi, C., Pettener, D. & Luiselli, D., Dec 1 2015, In : PLoS One. 10, 12, e0144391.

Research output: Contribution to journalArticle

Genome-Wide Scan Informed by Age-Related Disease Identifies Loci for Exceptional Human Longevity

Fortney, K., Dobriban, E., Garagnani, P., Pirazzini, C., Monti, D., Mari, D., Atzmon, G., Barzilai, N., Franceschi, C., Owen, A. B. & Kim, S. K., 2015, In : PLoS Genetics. 11, 12, e1005728.

Research output: Contribution to journalArticle

Genomics and epigenomics

Garagnani, P., Terlizzi, R., Cevoli, S., Capellari, S., Pierangeli, G., Pirazzini, C., Bacalini, M. G., Franceschi, C. & Cortelli, P., Dec 1 2015, In : Journal of Headache and Pain. 16, p. 1 1 p., A7.

Research output: Contribution to journalArticle

Identification of a DNA methylation signature in blood cells from persons with down syndrome

Bacalini, M. G., Gentilini, D., Boattini, A., Giampieri, E., Pirazzini, C., Giuliani, C., Fontanesi, E., Scurti, M., Remondini, D., Capri, M., Cocchi, G., Ghezzo, A., Rio, A. D., Luiselli, D., Vitale, G., Mari, D., Castellani, G., Fraga, M., Di Blasio, A. M., Salvioli, S. & 2 others, Franceschi, C. & Garagnani, P., 2015, In : Aging. 7, 2, p. 82-96 15 p.

Research output: Contribution to journalArticle

Impact of diet and nutraceutical supplementation on inflammation in elderly people. Results from the RISTOMED study, an open-label randomized control trial

Ostan, R., Béné, M. C., Spazzafumo, L., Pinto, A., Donini, L. M., Pryen, F., Charrouf, Z., Valentini, L., Lochs, H., Bourdel-Marchasson, I., Blanc-Bisson, C., Buccolini, F., Brigidi, P., Franceschi, C. & D'Alessio, P. A., Feb 27 2015, (Accepted/In press) In : Clinical Nutrition.

Research output: Contribution to journalArticle

Impact of personalized diet and probiotic supplementation on inflammation, nutritional parameters and intestinal microbiota - The "RISTOMED project": Randomized controlled trial in healthy older people

Valentini, L., Pinto, A., Bourdel-Marchasson, I., Ostan, R., Brigidi, P., Turroni, S., Hrelia, S., Hrelia, P., Bereswill, S., Fischer, A., Leoncini, E., Malaguti, M., Blanc-Bisson, C., Durrieu, J., Spazzafumo, L., Buccolini, F., Pryen, F., Donini, L. M., Franceschi, C. & Lochs, H., Aug 1 2015, In : Clinical Nutrition. 34, 4, p. 593-602 10 p.

Research output: Contribution to journalArticle

Inferring the genetic history of lactase persistence along the Italian peninsula from a large genomic interval surrounding the LCT gene

De Fanti, S., Sazzini, M., Giuliani, C., Frazzoni, F., Sarno, S., Boattini, A., Marasco, E., Mantovani, V., Franceschi, C., Moral, P., Garagnani, P. & Luiselli, D., Dec 1 2015, In : American Journal of Physical Anthropology. 158, 4, p. 708-718 11 p.

Research output: Contribution to journalArticle

Inflammaging and Cancer: A challenge for the mediterranean diet

Ostan, R., Lanzarini, C., Pini, E., Scurti, M., Vianello, D., Bertarelli, C., Fabbri, C., Izzi, M., Palmas, G., Biondi, F., Martucci, M., Bellavista, E., Salvioli, S., Capri, M., Franceschi, C. & Santoro, A., Apr 9 2015, In : Nutrients. 7, 4, p. 2589-2621 33 p.

Research output: Contribution to journalArticle

Interventions to Slow Aging in Humans: Are We Ready?

Longo, V. D., Antebi, A., Bartke, A., Barzilai, N., Brown-Borg, H. M., Caruso, C., Curiel, T. J., de Cabo, R., Franceschi, C., Gems, D., Ingram, D. K., Johnson, T. E., Kennedy, B. K., Kenyon, C., Klein, S., Kopchick, J. J., Lepperdinger, G., Madeo, F., Mirisola, M. G., Mitchell, J. R. & 10 others, Passarino, G., Rudolph, K. L., Sedivy, J. M., Shadel, G. S., Sinclair, D. A., Spindler, S. R., Suh, Y., Vijg, J., Vinciguerra, M. & Fontana, L., 2015, (Accepted/In press) In : Aging Cell.

Research output: Contribution to journalArticle

Low tobacco-related cancer incidence in offspring of long-lived siblings: A comparison with Danish national cancer registry data

Pedersen, J. K., Skytthe, A., McGue, M., Honig, L. S., Franceschi, C., Kirkwood, T. B. L., Passarino, G., Slagboom, P. E., Vaupel, J. W. & Christensen, K., Aug 1 2015, In : Annals of Epidemiology. 25, 8, p. 569-574 6 p.

Research output: Contribution to journalArticle

MARK-AGE biomarkers of ageing

Bürkle, A., Moreno-Villanueva, M., Bernhard, J., Blasco, M., Zondag, G., Hoeijmakers, J. H. J., Toussaint, O., Grubeck-Loebenstein, B., Mocchegiani, E., Collino, S., Gonos, E. S., Sikora, E., Gradinaru, D., Dollé, M., Salmon, M., Kristensen, P., Griffiths, H. R., Libert, C., Grune, T., Breusing, N. & 10 others, Simm, A., Franceschi, C., Capri, M., Talbot, D., Caiafa, P., Friguet, B., Slagboom, P. E., Hervonen, A., Hurme, M. & Aspinall, R., Nov 1 2015, In : Mechanisms of Ageing and Development. 151, p. 2-12 11 p.

Research output: Contribution to journalArticle

MARK-AGE population: From the human model to new insights

Capri, M., Moreno-Villanueva, M., Cevenini, E., Pini, E., Scurti, M., Borelli, V., Palmas, M. G., Zoli, M., Schön, C., Siepelmeyer, A., Bernhardt, J., Fiegl, S., Zondag, G., de Craen, A. J. M., Hervonen, A., Hurme, M., Sikora, E., Gonos, E. S., Voutetakis, K., Toussaint, O. & 4 others, Debacq-Chainiaux, F., Grubeck-Loebenstein, B., Bürkle, A. & Franceschi, C., Nov 1 2015, In : Mechanisms of Ageing and Development. 151, p. 13-17 5 p.

Research output: Contribution to journalArticle

MARK-AGE standard operating procedures (SOPs): A successful effort

Moreno-Villanueva, M., Capri, M., Breusing, N., Siepelmeyer, A., Sevini, F., Ghezzo, A., de Craen, A. J. M., Hervonen, A., Hurme, M., Schön, C., Grune, T., Franceschi, C. & Bürkle, A., Nov 1 2015, In : Mechanisms of Ageing and Development. 151, p. 18-25 8 p.

Research output: Contribution to journalArticle

Metformin improves putative longevity effectors in peripheral mononuclear cells from subjects with prediabetes. A randomized controlled trial

Vigili de Kreutzenberg, S., Ceolotto, G., Cattelan, A., Pagnin, E., Mazzucato, M., Garagnani, P., Borelli, V., Bacalini, M. G., Franceschi, C., Fadini, G. P. & Avogaro, A., Jul 1 2015, In : Nutrition, Metabolism and Cardiovascular Diseases. 25, 7, p. 686-693 8 p.

Research output: Contribution to journalArticle

N-Glycomic changes in serum proteins in type 2 diabetes mellitus correlate with complications and with metabolic syndrome parameters

Testa, R., Vanhooren, V., Bonfigli, A. R., Boemi, M., Olivieri, F., Ceriello, A., Genovese, S., Spazzafumo, L., Borelli, V., Bacalini, M. G., Salvioli, S., Garagnani, P., Dewaele, S., Libert, C. & Franceschi, C., Mar 20 2015, In : PLoS One. 10, 3, e0119983.

Research output: Contribution to journalArticle

Plasma N-Glycome Signature of Down Syndrome

Borelli, V., Vanhooren, V., Lonardi, E., Reiding, K. R., Capri, M., Libert, C., Garagnani, P., Salvioli, S., Franceschi, C. & Wuhrer, M., Oct 2 2015, In : Journal of Proteome Research. 14, 10, p. 4232-4245 14 p.

Research output: Contribution to journalArticle

Population-specific association of genes for telomere-associated proteins with longevity in an Italian population

Crocco, P., Barale, R., Rose, G., Rizzato, C., Santoro, A., De Rango, F., Carrai, M., Fogar, P., Monti, D., Biondi, F., Bucci, L., Ostan, R., Tallaro, F., Montesanto, A., Zambon, C. F., Franceschi, C., Canzian, F., Passarino, G. & Campa, D., Jun 15 2015, In : Biogerontology. 16, 3, p. 353-364 12 p.

Research output: Contribution to journalArticle

Quality control data of physiological and immunological biomarkers measured in serum and plasma

Jansen, E., Beekhof, P., Cremers, J., Weinberger, B., Fiegl, S., Toussaint, O., Bernhard, J., Gonos, E., Capri, M., Franceschi, C., Sikora, E., Moreno-Villanueva, M., Breusing, N., Grune, T., Bürkle, A. & Dollé, M. E. T., Jan 30 2015, In : Mechanisms of Ageing and Development. 151, p. 54-59 6 p.

Research output: Contribution to journalArticle

Quinazolinedione SIRT6 inhibitors sensitize cancer cells to chemotherapeutics

Sociali, G., Galeno, L., Parenti, M. D., Grozio, A., Bauer, I., Passalacqua, M., Boero, S., Donadini, A., Millo, E., Bellotti, M., Sturla, L., Damonte, P., Puddu, A., Ferroni, C., Varchi, G., Franceschi, C., Ballestrero, A., Poggi, A., Bruzzone, S., Nencioni, A. & 1 others, Del Rio, A., Aug 24 2015, In : European Journal of Medicinal Chemistry. 102, p. 530-539 10 p.

Research output: Contribution to journalArticle

Reconfiguration of DNA methylation in aging

Zampieri, M., Ciccarone, F., Calabrese, R., Franceschi, C., Bürkle, A. & Caiafa, P., Nov 1 2015, In : Mechanisms of Ageing and Development. 151, p. 60-70 11 p.

Research output: Contribution to journalArticle