1969 …2020

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Age-related increase of mitomycin C-induced micronuclei in lymphocytes from Down's syndrome subjects

Scarfi, M. R., Cossarizza, A., Monti, D., Bersani, F., Zannotti, M., Lioi, M. B. & Franceschi, C., 1990, In : Mutation Research DNAging. 237, 5-6, p. 247-252 6 p.

Research output: Contribution to journalArticle

Age-related inflammation: The contribution of different organs, tissues and systems. How to face it for therapeutic approaches

Cevenini, E., Caruso, C., Candore, G., Capri, M., Nuzzo, D., Duro, G., Rizzo, C., Colonna-Romano, G., Lio, D., Di Carlo, D., Palmas, M. G., Scurti, M., Pini, E., Franceschi, C. & Vasto, S., 2010, In : Current Pharmaceutical Design. 16, 6, p. 609-618 10 p.

Research output: Contribution to journalArticle

Age-related modifications in circulating IL-15 levels in humans

Gangemi, S., Basile, G., Monti, D., Merendino, R. A., Di Pasquale, G., Bisignano, U., Nicita-Mauro, V. & Franceschi, C., Aug 31 2005, In : Mediators of Inflammation. 2005, 4, p. 245-247 3 p.

Research output: Contribution to journalArticle

Aging, longevity, and cancer: Studies in Down's syndrome and centenarians

Franceschi, C., Monti, D., Cossarizza, A., Fagnoni, F., Passeri, G. & Sansoni, P., 1991, In : Annals of the New York Academy of Sciences. 621, p. 428-440 13 p.

Research output: Contribution to journalArticle

Aging, longevity, inflammation, and cancer

Caruso, C., Lio, D., Cavallone, L. & Franceschi, C., 2004, In : Annals of the New York Academy of Sciences. 1028, p. 1-13 13 p.

Research output: Contribution to journalArticle

Aging of the immune system as a prognostic factor for human longevity

Larbi, A., Franceschi, C., Mazzatti, D., Solana, R., Wikby, A. & Pawelec, G., Apr 2008, In : Physiology. 23, 2, p. 64-74 11 p.

Research output: Contribution to journalArticle

AKEntAnnos. The Sardinia study of extreme longevity

Deiana, L., Ferrucci, L., Pes, G. M., Carru, C., Delitala, G., Ganau, A., Mariotti, S., Nieddu, A., Pettinato, S., Putzu, P., Franceschi, C. & Baggio, G., Jun 1999, In : Aging clinical and experimental research. 11, 3, p. 142-149 8 p.

Research output: Contribution to journalArticle

Allele frequencies of +874T→A single nucleotide polymorphism at the first intron of IFN-γ gene in Alzheimer's disease patients

Scola, L., Licastro, F., Chiappelli, M., Franceschi, C., Grimaldi, L. M., Crivello, A., Colonna-Romano, G., Candore, G., Lio, D. & Caruso, C., Aug 2003, In : Aging clinical and experimental research. 15, 4, p. 292-295 4 p.

Research output: Contribution to journalArticle

Allele frequencies of +874T → A single nucleotide polymorphism at the first intron of interferon-γ gene in a group of Italian centenarians

Lio, D., Scola, L., Crivello, A., Bonafè, M., Franceschi, C., Olivieri, F., Colonna-Romano, G., Candore, G. & Caruso, C., Jan 3 2002, In : Experimental Gerontology. 37, 2-3, p. 315-319 5 p.

Research output: Contribution to journalArticle

A logistic regression model for measuring gene-longevity associations

Tan, Q., Yashin, A. I., De Benedictis, G., Cintolesi, F., Rose, G., Bonafe, M., Franceschi, C., Vach, W. & Vaupel, J. W., 2001, In : Clinical Genetics. 60, 6, p. 463-469 7 p.

Research output: Contribution to journalArticle

Alpha1-antitrypsin heterozygosity plays a positive role in attainment of longevity

Listì, F., Candore, G., Grimaldi, M. P., Lio, D., Colonna-Romano, G., Orlando, V., Caruso, M., Hoffmann, E., Paolisso, G., Franceschi, C. & Caruso, C., Apr 2007, In : Biogerontology. 8, 2, p. 139-145 7 p.

Research output: Contribution to journalArticle

Alpine Skiing With total knee ArthroPlasty (ASWAP): Impact on molecular and architectural features of musculo-skeletal ageing

Narici, M., Conte, M., Salvioli, S., Franceschi, C., Selby, A., Dela, F., Rieder, F., Kösters, A. & Müller, E., Aug 1 2015, In : Scandinavian Journal of Medicine and Science in Sports. 25, S2, p. 33-39 7 p.

Research output: Contribution to journalArticle

Alterations of the capping phenomenon on lymphocytes from aged and Down's syndrome subjects

Chiricolo, M., Minelli, L., Licastro, F., Tabacchi, P., Zannotti, M. & Franceschi, C., 1984, In : Gerontology. 30, 3, p. 145-152 8 p.

Research output: Contribution to journalArticle

A Mathematical Model for the Immunosenescence

Luciani, F., Turchetti, G., Franceschi, C. & Valensin, S., May 2001, In : Rivista di Biologia - Biology Forum. 94, 2, p. 305-318 14 p.

Research output: Contribution to journalArticle

A Mediterranean-like dietary pattern with vitamin D3 (10 µg/d) supplements reduced the rate of bone loss in older Europeans with osteoporosis at baseline: results of a 1-y randomized controlled trial

Jennings, A., Cashman, K. D., Gillings, R., Cassidy, A., Tang, J., Fraser, W., Dowling, K. G., Hull, G. L. J., Berendsen, A. A. M., de Groot, L. C. P. G. M., Pietruszka, B., Wierzbicka, E., Ostan, R., Bazzocchi, A., Battista, G., Caumon, E., Meunier, N., Malpuech-Brugère, C., Franceschi, C., Santoro, A. & 1 others, Fairweather-Tait, S. J., Sep 1 2018, In : American Journal of Clinical Nutrition. 108, 3, p. 633–640 8 p.

Research output: Contribution to journalArticle

A meta-analysis on age-associated changes in blood DNA methylation: Results from an original analysis pipeline for Infinium 450k data

Bacalini, M. G., Boattini, A., Gentilini, D., Giampieri, E., Pirazzini, C., Giuliani, C., Fontanesi, E., Remondini, D., Capri, M., Rio, A. D., Luiselli, D., Vitale, G., Mari, D., Castellani, G., Di Blasio, A. M., Salvioli, S., Franceschi, C. & Garagnani, P., 2015, In : Aging. 7, 2, p. 97-109 13 p.

Research output: Contribution to journalArticle

A microELISA assay to detect anti-liver-specific protein antibodies in the sera of patients with liver diseases

Lenzi, M., Cassani, F., Bianchi, F. B. & Franceschi, C., Feb 25 1983, In : Journal of Immunological Methods. 57, 1-3, p. 59-69 11 p.

Research output: Contribution to journalArticle

Analisi del metiloma negli ultralongevi e nei loro figli e stato di salute

Translated title of the contribution: Genome-wide dna methylation profiles in centenarians and their offspring reveal features of longevity and healthy ageingMari, D., Gentilini, D., Castaldi, D., Remondini, D., Ogliari, G., Ostan, R., Buci, L., Sirchia, S. M., Tabano, S., Cavagnini, F., Monti, D., Franceschi, C., Di Blasio, A. M. & Vitale, G., Oct 2011, In : Giornale di Gerontologia. 59, 5, p. 273-284 12 p.

Research output: Contribution to journalArticle

An allele of HRAS1 3′variable number of tandem repeats is a frailty allele: Implication for an evolutionarily-conserved pathway involved in longevity

Bonafè, M., Barbi, C., Olivieri, F., Yashin, A., Andreev, K. F., Vaupel, J. W., De Benedictis, G., Rose, G., Carrieri, G., Jazwinski, S. M. & Franceschi, C., Mar 6 2002, In : Gene. 286, 1, p. 121-126 6 p.

Research output: Contribution to journalArticle

Analysis of HLA-DQA, HLA-DQB frequencies in a group of Sardinian centenarians

Scola, L., Lio, D., Crivello, A., Candore, G., Forte, G. I., Colonna-Romano, G., Pes, M. G., Carru, C., Ferrucci, L., Deiana, L., Baggio, G., Franceschi, C. & Caruso, C., Mar 2006, In : Rejuvenation Research. 9, 1, p. 157-160 4 p.

Research output: Contribution to journalArticle

Analysis of HLA-DRB1,DQA1,DQB1 haplotypes in Sardinian centenarians

Scola, L., Lio, D., Candore, G., Forte, G. I., Crivello, A., Colonna-Romano, G., Pes, M. G., Carru, C., Ferrucci, L., Deiana, L., Baggio, G., Franceschi, C. & Caruso, C., Feb 2008, In : Experimental Gerontology. 43, 2, p. 114-118 5 p.

Research output: Contribution to journalArticle

Analysis of Population Substructure in Two Sympatric Populations of Gran Chaco, Argentina

Sevini, F., Yao, D. Y., Lomartire, L., Barbieri, A., Vianello, D., Ferri, G., Moretti, E., Dasso, M. C., Garagnani, P., Pettener, D., Franceschi, C., Luiselli, D. & Franceschi, Z. A., May 22 2013, In : PLoS One. 8, 5, e64054.

Research output: Contribution to journalArticle

Analysis of the machinery and intermediates of the 5hmC-mediated DNA demethylation pathway in aging on samples from the MARKAGE Study

Valentini, E., Zampieri, M., Malavolta, M., Bacalini, M. G., Calabrese, R., Guastafierro, T., Reale, A., Franceschi, C., Hervonen, A., Koller, B., Bernhardt, J., Eline Slagboom, P., Toussaint, O., Sikora, E., Gonos, E. S., Breusing, N., Grune, T., Jansen, E., Dollé, M. E. T., Moreno-Villanueva, M. & 4 others, Sindlinger, T., Bürkle, A., Ciccarone, F. & Caiafa, P., 2016, In : Aging. 8, 9, p. 1896-1922 27 p.

Research output: Contribution to journalArticle

An APOE haplotype associated with decreased 4 expression increases the risk of late onset alzheimer's disease

Lescai, F., Chiamenti, A. M., Codemo, A., Pirazzini, C., D'Agostino, G., Ruaro, C., Ghidoni, R., Benussi, L., Galimberti, D., Esposito, F., Marchegiani, F., Cardelli, M., Olivieri, F., Nacmias, B., Sorbi, S., Tagliavini, F., Albani, D., Boneschi, F. M., Binetti, G., Santoro, A. & 5 others, Forloni, G., Scarpini, E., Crepaldi, G., Gabelli, C. & Franceschi, C., 2011, In : Journal of Alzheimer's Disease. 24, 2, p. 235-245 11 p.

Research output: Contribution to journalArticle

Ancient pathogen-driven adaptation triggers increased susceptibility to nonceliac wheat sensitivity in present-day European populations

Sazzini, M., De Fanti, S., Cherubini, A., Quagliariello, A., Profiti, G., Martelli, P. L., Casadio, R., Ricci, C., Campieri, M., Lanzini, A., Volta, U., Caio, G., Franceschi, C., Spisni, E. & Luiselli, D., 2016, In : Genes and Nutrition. 11, 1

Research output: Contribution to journalArticle

A Novel Action for Adenosine: Apoptosis of Astroglial Cells in Rat-Brain Primary Cultures

Abbracchio, M. P., Ceruti, S., Barbieri, D., Franceschi, C., Malorni, W., Biondo, L., Burnstock, G. & Cattabeni, F., Aug 24 1995, In : Biochemical and Biophysical Research Communications. 213, 3, p. 908-915 8 p.

Research output: Contribution to journalArticle

A novel mitochondrial DNA-like sequence insertion polymorphism in Intron I of the FOXO1A gene

Giampieri, C., Centurelli, M., Bonafè, M., Olivieri, F., Cardelli, M., Marchegiani, F., Cavallone, L., Giovagnetti, S., Mugianesi, E., Carrieri, G., Lisa, R., Cenerelli, S., Testa, R., Boemi, M., Petropoulou, C., Gonos, E. S. & Franceschi, C., Mar 3 2004, In : Gene. 327, 2, p. 215-219 5 p.

Research output: Contribution to journalArticle

A novel sampling design to explore gene-longevity associations: The ECHA study

De Rango, F., Dato, S., Bellizzi, D., Rose, G., Marzi, E., Cavallone, L., Franceschi, C., Skytthe, A., Jeune, B., Cournil, A., Robine, J. M., Gampe, J., Vaupel, J. W., Mari, V., Feraco, E., Passarino, G., Novelletto, A. & De Benedictis, G., Feb 2008, In : European Journal of Human Genetics. 16, 2, p. 236-242 7 p.

Research output: Contribution to journalArticle

A novel VNTR enhancer within the SIRT3 gene, a human homologue of SIR2, is associated with survival at oldest ages

Bellizzi, D., Rose, G., Cavalcante, P., Covello, G., Dato, S., De Rango, F., Greco, V., Maggiolini, M., Feraco, E., Mari, V., Franceschi, C., Passarino, G. & De Benedictis, G., Feb 2005, In : Genomics. 85, 2, p. 258-263 6 p.

Research output: Contribution to journalArticle

Antiapoptotic effect of c-fes protooncogene during granulocytic differentiation

Ferrari, S., Manfredini, R., Tagliafico, E., Grande, A., Barbieri, D., Balestri, R., Pizzanelli, M., Zucchini, P., Citro, G., Zupi, G., Franceschi, C. & Torelli, U., 1994, In : Leukemia. 8, SUPPL.1

Research output: Contribution to journalArticle

Anti-beta 2 glycoprotein I antibodies in centenarians

Meroni, P. L., Mari, D., Monti, D., Coppola, R., Capri, M., Salvioli, S., Tincani, A., Gerli, R. & Franceschi, C., Oct 2004, In : Experimental Gerontology. 39, 10, p. 1459-1465 7 p.

Research output: Contribution to journalArticle

Antibody response in partridge (Perdix perdix L.) 1. Effect of sex and age on the immune response to sheep red blood cells (SRBC), newcastle disease virus (NDV) and Brucella abortus (Buck 19)

Randi, E., Chiricolo, M., Spagnesi, M., Ghedini, I., Savigni, G., Giovannini, A. & Franceschi, C., 1985, In : Developmental and Comparative Immunology. 9, 4, p. 679-690 12 p.

Research output: Contribution to journalArticle

Anti-inflammatory effect of ubiquinol-10 on young and senescent endothelial cells via miR-146a modulation

Olivieri, F., Lazzarini, R., Babini, L., Prattichizzo, F., Rippo, M. R., Tiano, L., Di Nuzzo, S., Graciotti, L., Festa, R., Brugè, F., Orlando, P., Silvestri, S., Capri, M., Palma, L., Magnani, M., Franceschi, C., Littarru, G. P. & Procopio, A. D., 2013, In : Free Radical Biology and Medicine. 63, p. 410-420 11 p.

Research output: Contribution to journalArticle

Antioxidants linked with physical, cognitive and psychological frailty: Analysis of candidate biomarkers and markers derived from the MARK-AGE study

Rietman, M. L., Spijkerman, A. M. W., Wong, A., van Steeg, H., Bürkle, A., Moreno-Villanueva, M., Sindlinger, T., Franceschi, C., Grubeck-Loebenstein, B., Bernhardt, J., Slagboom, P. E., Toussaint, O., Debacq-Chainiaux, F., Sikora, E., Gonos, E. S., Breusing, N., Stuetz, W., Weber, D., Grune, T., Basso, A. & 6 others, Piacenza, F., Malavolta, M., Collino, S., Jansen, E. H. J. M., Verschuren, W. M. M. & Dollé, M. E. T., Apr 30 2018, In : Mechanisms of Ageing and Development. 177, p. 135-143 9 p.

Research output: Contribution to journalArticle

Antiproliferative activity of 3-aminobenzamide in A431 carcinoma cells is associated with a target effect on cytoskeleton

Tiozzo, R., Monti, D., Straface, E., Capri, M., Croce, M. A., Rainaldi, G., Franceschi, C. & Malorni, W., Aug 23 1996, In : Biochemical and Biophysical Research Communications. 225, 3, p. 826-832 7 p.

Research output: Contribution to journalArticle

Antisense inhibition of c-fes proto-oncogene blocks PMA-induced macrophage differentiation in HL60 and in FDC-P1/MAC-11 cells

Manfredini, R., Balestri, R., Tagliafico, E., Trevisan, F., Pizzanelli, M., Grande, A., Barbieri, D., Zucchini, P., Citro, G., Franceschi, C. & Ferrari, S., Jan 1 1997, In : Blood. 89, 1, p. 135-145 11 p.

Research output: Contribution to journalArticle

A parallel randomized trial on the effect of a healthful diet on inflammageing and its consequences in European elderly people: Design of the NU-AGE dietary intervention study

Berendsen, A., Santoro, A., Pini, E., Cevenini, E., Ostan, R., Pietruszka, B., Rolf, K., Cano, N., Caille, A., Lyon-Belgy, N., Fairweather-Tait, S., Feskens, E., Franceschi, C. & de Groot, C. P. G. M., 2014, In : Mechanisms of Ageing and Development. 134, 11-12, p. 523-530 8 p.

Research output: Contribution to journalArticle

A patient with PMP22-related hereditary neuropathy and DBH-gene-related dysautonomia

Bartoletti-Stella, A., Chiaro, G., Calandra-Buonaura, G., Contin, M., Scaglione, C., Barletta, G., Cecere, A., Garagnani, P., Tieri, P., Ferrarini, A., Piras, S., Franceschi, C., Delledonne, M., Cortelli, P. & Capellari, S., Oct 1 2015, In : Journal of Neurology. 262, 10, p. 2373-2381 9 p.

Research output: Contribution to journalArticle

Apoptosis, DNA damage and ubiquitin expression in normal and mdx muscle fibers after exercise

Sandri, M., Carraro, U., Podhorska-Okolov, M., Rizzi, C., Arslan, P., Monti, D. & Franceschi, C., Oct 16 1995, In : FEBS Letters. 373, 3, p. 291-295 5 p.

Research output: Contribution to journalArticle

Apoptosis and immunosenescence

Monti, D., Cossarizza, A., Salvioli, S., Barbieri, D., Macchioni, S., Guido, M., Baggio, G. & Franceschi, C., 1995, In : Aging clinical and experimental research. 7, 6, p. 461-463 3 p.

Research output: Contribution to journalArticle

Apoptosis and spermatogenesis: Evidence from an in vivo model of testosterone withdrawal in the adult rat

Troiano, L., Fustini, M. F., Lovato, E., Frasoldati, A., Malorni, W., Capri, M., Grassilli, E., Marrama, P. & Franceschi, C., 1994, In : Biochemical and Biophysical Research Communications. 202, 3, p. 1315-1321 7 p.

Research output: Contribution to journalArticle

Apoptosis by 2-chloro-2'-deoxy-adenosine and 2-chloro-adenosine in human peripheral blood mononuclear cells

Barbieri, D., Abbracchio, M. P., Salvioli, S., Monti, D., Cossarizza, A., Ceruti, S., Brambilla, R., Cattabeni, F., Jacobson, K. A. & Franceschi, C., May 1 1998, In : Neurochemistry International. 32, 5-6, p. 493-504 12 p.

Research output: Contribution to journalArticle

Apoptosis induced by 2-chloro-adenosine and 2-chloro-2'-deoxy-adenosine in a human astrocytoma cell line: Differential mechanisms and possible clinical relevance

Ceruti, S., Franceschi, C., Barbieri, D., Malorni, W., Camurri, A., Giammarioli, A. M., Ambrosini, A., Racagni, G., Cattabeni, F. & Abbracchio, M. P., May 1 2000, In : Journal of Neuroscience Research. 60, 3, p. 388-400 13 p.

Research output: Contribution to journalArticle

Apoptosis-like, reversible changes in plasma membrane asymmetry and permeability, and transient modifications in mitochondrial membrane potential induced by curcumin in rat thymocytes

Jaruga, E., Salvioli, S., Dobrucki, J., Chrul, S., Bandorowicz-Pikuła, J., Sikora, E., Franceschi, C., Cossarizza, A. & Bartosz, G., Aug 21 1998, In : FEBS Letters. 433, 3, p. 287-293 7 p.

Research output: Contribution to journalArticle

Apoptosis of skeletal and cardiac muscles and physical exercise

Carraro, U. & Franceschi, C., Feb 1997, In : Aging clinical and experimental research. 9, 1-2, p. 19-34 16 p.

Research output: Contribution to journalArticle

Apoptosis - Programmed cell death: A role in the aging process?

Monti, D., Troiano, L., Tropea, F., Grassilli, E., Cossarizza, A., Barozzi, D., Pelloni, M. C., Tamassia, M. G., Bellomo, G. & Franceschi, C., Jun 1992, In : American Journal of Clinical Nutrition. 55, SUPPL. 6

Research output: Contribution to journalArticle