1969 …2020

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Synergistic immunodepressive effect of 7,12-dimethylbenz(a)anthracene and urethan in the rat.

Perocco, P., Franceschi, C., Di Marco, A. T. & Prodi, G., Apr 1971, In : Proceedings of the Society for Experimental Biology and Medicine. 136, 4, p. 1024-1026 3 p.

Research output: Contribution to journalArticle

Survival features of EBV-stabilized cells from centenarians: Morpho-functional and transcriptomic analyses

Matarrese, P., Tinari, A., Ascione, B., Gambardella, L., Remondini, D., Salvioli, S., Tenedini, E., Tagliafico, E., Franceschi, C. & Malorni, W., Dec 2012, In : Age. 34, 6, p. 1341-1359 19 p.

Research output: Contribution to journalArticle

Suggestions from Geroscience for the Genetics of Age-Related Diseases

Franceschi, C. & Garagnani, P., Nov 1 2016, In : PLoS Genetics. 12, 11, e1006399.

Research output: Contribution to journalArticle

Successful immunosenescence and the remodelling of immune responses with ageing

Franceschi, C., Monti, D., Barbieri, D., Salvioli, S., Grassilli, E., Capri, M., Troiano, L., Guido, M., Bonafè, M., Tropea, F., Salomoni, P., Benatti, F., Bellesia, E., Macchioni, S., Anderlini, R., Sansoni, P., Mariotti, S., Wratten, M. L., Tetta, C. & Cossarizza, A., 1996, In : Nephrology Dialysis Transplantation. 11, SUPPL. 9, p. 18-25 8 p.

Research output: Contribution to journalArticle

Study of the association with - 330T/G IL-2 in a population of centenarians from Centre and South Italy

Scola, L., Candore, G., Colonna-Romano, G., Crivello, A., Forte, G. I., Paolisso, G., Franceschi, C., Lio, D. & Caruso, C., Dec 2005, In : Biogerontology. 6, 6, p. 425-429 5 p.

Research output: Contribution to journalArticle

STUDIO CLINICO-IMMUNOLOGICO DI SEI CASI DI MORBO DI BEHCET

Translated title of the contribution: Clinicoimmunological study of six cases of Behcet's diseaseSilingardi, V., Montemurno, C., Venezia, L., Franceschi, C., Riva, P. C., Emilia, G., Masi, M., Merelli, E., Torelli, G., Licastro, F., Fantini, M. P. & Federico, M., 1979, In : Minerva Medica. 70, 48, p. 3269-3284 16 p.

Research output: Contribution to journalArticle

Studies on immunoproteasome in human liver. Part I: Absence in fetuses, presence in normal subjects, and increased levels in chronic active hepatitis and cirrhosis

Vasuri, F., Capizzi, E., Bellavista, E., Mishto, M., Santoro, A., Fiorentino, M., Capri, M., Cescon, M., Grazi, G. L., Grigioni, W. F., D'Errico-Grigioni, A. & Franceschi, C., Jun 25 2010, In : Biochemical and Biophysical Research Communications. 397, 2, p. 301-306 6 p.

Research output: Contribution to journalArticle

Studies of the relationship between cell proliferation and cell death. II. Early gene expression during concanavalin A-induced proliferation or dexamethasone-induced apoptosis of rat thymocytes

Grassilli, E., de Prati, A. C., Monti, D., Troiano, L., Menegazzi, M., Barbieri, D., Franceschi, C. & Suzuki, H., Nov 16 1992, In : Biochemical and Biophysical Research Communications. 188, 3, p. 1261-1266 6 p.

Research output: Contribution to journalArticle

Structural characterization of p53 isoforms due to the polymorphism at codon 72 by mass spectrometry and circular dichroism

Naldi, M., Pistolozzi, M., Bertucci, C., De Simone, A., Altilia, S., Pierini, M., Franceschi, C., Salvioli, S. & Andrisano, V., 2010, In : Journal of Pharmaceutical and Biomedical Analysis. 53, 2, p. 200-206 7 p.

Research output: Contribution to journalArticle

Strikingly higher frequency in centenarians and twins of mtDNA mutation causing remodeling of replication origin in leukocytes

Zhang, J., Asin-Cayuela, J., Fish, J., Michikawa, Y., Bonafé, M., Olivieri, F., Passarino, G., De Benedictis, G., Franceschi, C. & Attardi, G., Feb 4 2003, In : Proceedings of the National Academy of Sciences of the United States of America. 100, 3, p. 1116-1121 6 p.

Research output: Contribution to journalArticle

Stress response in the freshwater snail Planorbarius corneus (L.) (Gastropoda, Pulmonata): Interaction between CRF, ACTH, and biogenic amines

Ottaviani, E., Caselgrandi, E., Petraglia, F. & Franceschi, C., 1992, In : General and Comparative Endocrinology. 87, 3, p. 354-360 7 p.

Research output: Contribution to journalArticle

Stress, inflammation and natural immunity in the aging process: A new theory

Franceschi, C. & Ottaviani, E., 1997, In : Aging clinical and experimental research. 9, 4 SUPPL., p. 30-31 2 p.

Research output: Contribution to journalArticle

Stress, inflammation and natural immunity in the aging process: A new theory

Franceschi, C. & Ottaviani, E., 1997, In : Aging Milano. 9, 4 SUPPL., p. 30-31 2 p.

Research output: Contribution to journalArticle

Stochastic epigenetic mutations (DNA methylation) increase exponentially in human aging and correlate with X chromosome inactivation skewing in females

Gentilini, D., Garagnani, P., Pisoni, S., Bacalini, M. G., Calzari, L., Mari, D., Vitale, G., Franceschi, C. & Di Blasio, A. M., 2015, In : Aging. 7, 8, p. 568-578 11 p.

Research output: Contribution to journalArticle

Steroid regulation of cytokines. Relevance for TH1-to-TH2 shift?

Chiappelli, F., Manfrini, E., Franceschi, C., Cossarizza, A. & Black, K. L., 1994, In : Annals of the New York Academy of Sciences. 746, p. 204-215 12 p.

Research output: Contribution to journalArticle

Statistical strategies and stochastic predictive models for the MARK-AGE data

Giampieri, E., Remondini, D., Bacalini, M. G., Garagnani, P., Pirazzini, C., Yani, S. L., Giuliani, C., Menichetti, G., Zironi, I., Sala, C., Capri, M., Franceschi, C., Bürkle, A. & Castellani, G., Dec 2 2014, In : Mechanisms of Ageing and Development. 151, p. 45-53 9 p.

Research output: Contribution to journalArticle

Stable state analysis of an immune network model

Castellani, G. C., Giberti, C., Franceschi, C. & Bersani, F., Jun 1998, In : International Journal of Bifurcation and Chaos. 8, 6, p. 1285-1301 17 p.

Research output: Contribution to journalArticle

Spontaneous and mitomycin-C-induced micronuclei in lymphocytes from subjects affected by Turner's syndrome

Scarfi, M. R., Prisco, F., Bersani, F., Lioi, M. B., Zeni, O., Di Pietro, R., Franceschi, C., Motta, M., Iafusco, D. & Stoppoloni, G., Oct 25 1996, In : Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis. 357, 1-2, p. 183-190 8 p.

Research output: Contribution to journalArticle

Spontaneous and mitomycin-C-induced micronuclei in human lymphocytes exposed to extremely low frequency pulsed magnetic fields

Scarfi, M. R., Bersani, F., Cossarizza, A., Monti, D., Castellani, G., Cadossi, R., Franceschetti, G. & Franceschi, C., Apr 15 1991, In : Biochemical and Biophysical Research Communications. 176, 1, p. 194-200 7 p.

Research output: Contribution to journalArticle

Spectrin changes occur in erythrocytes from patients with Fanconi's anemia and their parents

Straface, E., Masella, R., Principe, D. D., Franceschi, C., Korkina, L. G., Zatterale, A., Pagano, G. & Malorni, W., Jul 14 2000, In : Biochemical and Biophysical Research Communications. 273, 3, p. 899-901 3 p.

Research output: Contribution to journalArticle

Specific interaction of human Tamm-Horsfall gylcoprotein with leucoagglutinin, a lectin from Phaseolus vulgaris (red kidney bean).

Serafini-Cessi, F., Franceschi, C. & Sperti, S., Nov 1 1979, In : Biochemical Journal. 183, 2, p. 381-388 8 p.

Research output: Contribution to journalArticle

Space/Population and Time/Age in DNA methylatlations and in mono- and di-zygotic twins of different age

Pirazzini, C., Giuliani, C., Bacalini, M. G., Boattini, A., Capri, M., Fontanesi, E., Marasco, E., Mantovani, V., Pierini, M., Pini, E., Luiselli, D., Franceschi, C. & Garagnani, P., Jul 2012, In : Aging. 4, 7, p. 509-520 12 p.

Research output: Contribution to journalArticle

Somatic point mutations in mtDNA control region are influenced by genetic background and associated with healthy aging: A GEHA study

Rose, G., Romeo, G., Dato, S., Crocco, P., Bruni, A. C., Hervonen, A., Majamaa, K., Sevini, F., Franceschi, C. & Passarino, G., 2010, In : PLoS One. 5, 10, e13395.

Research output: Contribution to journalArticle

Slug/β-catenin-dependent proinflammatory phenotype in hypoxic breast cancer stem cells

Storci, G., Bertoni, S., De Carolis, S., Papi, A., Nati, M., Ceccarelli, C., Pirazzini, C., Garagnani, P., Ferrarini, A., Buson, G., Delledonne, M., Fiorentino, M., Capizzi, E., Gruppioni, E., Taffurelli, M., Santini, D., Franceschi, C., Bandini, G., Bonifazi, F. & Bonafé, M., Nov 2013, In : American Journal of Pathology. 183, 5, p. 1688-1697 10 p.

Research output: Contribution to journalArticle

Sister chromatid exchanges and DNA repair capability in sanitary workers exposed to ethylene oxide: evaluation of the dose-effect relationship.

Sarto, F., Clonfero, E., Bartolucci, G. B., Franceschi, C., Chiricolo, M. & Levis, A. G., 1987, In : American Journal of Industrial Medicine. 12, 5, p. 625-637 13 p.

Research output: Contribution to journalArticle

Simple sugars inhibit proliferation of human T lymphocytes in autologous and allogeneic mixed lymphocyte reactions

Licastro, F., Chiricolo, M., Tabacchi, P. & Franceschi, C., 1987, In : Cellular Immunology. 107, 1, p. 15-23 9 p.

Research output: Contribution to journalArticle

Shortage of circulating naive CD8+ T cells provides new insights on immunodeficiency in aging

Fagnoni, F. F., Vescovini, R., Passeri, G., Bologna, G., Pedrazzoni, M., Lavagetto, G., Casti, A., Franceschi, C., Passeri, M. & Sansoni, P., May 1 2000, In : Blood. 95, 9, p. 2860-2868 9 p.

Research output: Contribution to journalArticle

SGP-2, apoptosis, and aging

Grassilli, E., Bettuzzi, S., Trolano, L., Ingletti, M. C., Monti, D., Corti, A. & Franceschi, C., 1992, In : Annals of the New York Academy of Sciences. 663, p. 471-474 4 p.

Research output: Contribution to journalArticle

Sex-specific longevity associations defined by Tyrosine Hydroxylase-Insulin-Insulin Growth Factor 2 haplotypes on the 11p15.5 chromosomal region

De Luca, M., Rose, G., Bonafè, M., Garasto, S., Greco, V., Weir, B. S., Franceschi, C. & De Benedictis, G., 2001, In : Experimental Gerontology. 36, 10, p. 1663-1671 9 p.

Research output: Contribution to journalArticle

Sex-Specific Associations of Blood-Based Nutrient Profiling With Body Composition in the Elderly

Konz, T., Santoro, A., Goulet, L., Bazzocchi, A., Battista, G., Nicoletti, C., Kadi, F., Ostan, R., Goy, M., Monnard, C., Martin, F-P., Feige, J. N., Franceschi, C. & Rezzi, S., 2018, In : Frontiers in Physiology. 9, p. 1935

Research output: Contribution to journalArticle

Serum profiling of healthy aging identifies phospho- and sphingolipid species as markers of human longevity

Montoliu, I., Scherer, M., Beguelin, F., DaSilva, L., Mari, D., Salvioli, S., Martin, F. P. J., Capri, M., Bucci, L., Ostan, R., Garagnani, P., Monti, D., Biagi, E., Brigidi, P., Kussmann, M., Rezzi, S., Franceschi, C. & Collino, S., Jan 2014, In : Aging. 6, 1, p. 9-25 17 p.

Research output: Contribution to journalArticle

Serum N-glycan profile shift during human ageing

Vanhooren, V., Dewaele, S., Libert, C., Engelborghs, S., De Deyn, P. P., Toussaint, O., Debacq-Chainiaux, F., Poulain, M., Glupczynski, Y., Franceschi, C., Jaspers, K., van der Pluijm, I., Hoeijmakers, J. & Chen, C. C., Oct 2010, In : Experimental Gerontology. 45, 10, p. 738-743 6 p.

Research output: Contribution to journalArticle

Serum immunoglobulins and lymphocyte subpopulations derangement in Turner's syndrome

Cacciari, E., Masi, M., Fantini, M. P., Licastro, F., Cicognani, A., Pirazzoli, P., Villa, M. P., Specchia, F., Forabosco, A., Franceschi, C. & Martoni, L., 1981, In : Journal of Immunogenetics. 8, 5, p. 337-344 8 p.

Research output: Contribution to journalArticle

Serum IL-1β levels in health and disease: A population-based study. 'The InCHIANTI study'

Di Iorio, A., Ferrucci, L., Sparvieri, E., Cherubini, A., Volpato, S., Corsi, A., Bonafè, M., Franceschi, C., Abate, G. & Paganelli, R., Jun 21 2003, In : Cytokine. 22, 6, p. 198-205 8 p.

Research output: Contribution to journalArticle

Serum dehydroepiandrosterone sulfate (DHEA-S) and total antioxidant capacity (TAC) in healthy centenarian subjects.

Petruzzi, E., Orlando, C., Pinzani, P., Gallai, R., Ognibene, A., Grassi, E., Sorbi, S., Monti, D., Franceschi, C., Masotti, G. & Pazzagli, M., 1999, In : Journal of Endocrinological Investigation. 22, 10 Suppl, p. 76 1 p.

Research output: Contribution to journalArticle

Serum dehydroepiandrosterone sulfate (DHEA-S) and total antioxidant capacity (TAC) in healthy centenarian subjects

Petruzzi, E., Orlando, C., Pinzani, P., Gallai, R., Ognibene, A., Grassi, E., Sorbi, S., Monti, D., Franceschi, C., Masotti, G. & Pazzagli, M., 1999, In : Journal of Endocrinological Investigation. 22, 10 SUPPL. 1, p. 76 1 p.

Research output: Contribution to journalArticle

Sensitivity to genotoxic agents and immunological status in a case of Werner's syndrome

Monti, D., Cossarizza, A., Chiricolo, M., Vannini, P., Ciavarella, A. & Franceschi, C., 1992, In : Annals of the New York Academy of Sciences. 663, p. 429-431 3 p.

Research output: Contribution to journalArticle

Senescenza e sistema immunitario: L'esempio dei centenari

Translated title of the contribution: Senescence and immune system: The example of centenariansCossarizza, A., Gerli, R., Monti, D., Meroni, P. & Franceschi, C., 1997, In : Reumatismo. 49, 1, p. 41-46 6 p.

Research output: Contribution to journalArticle

Senescence, immortalization, and apoptosis: An intriguing relationship

Monti, D., Grassilli, E., Troiano, L., Cossarizza, A., Salvioli, S., Barbieri, D., Agnesini, C., Bettuzzi, S., Ingletti, M. C., Corti, A. & Franceschi, C., 1992, In : Annals of the New York Academy of Sciences. 673, p. 70-82 13 p.

Research output: Contribution to journalArticle

Sendai virus and herpes virus type 1 induce apoptosis in human peripheral blood mononuclear cells

Tropea, F., Troiano, L., Monti, D., Lovato, E., Malorni, W., Rainaldi, G., Mattana, P., Viscomi, G., Ingletti, M. C., Portolani, M., Cermelli, C., Cossarizza, A. & Franceschi, C., 1995, In : Experimental Cell Research. 218, 1, p. 63-70 8 p.

Research output: Contribution to journalArticle

Selective thymus-derived cell enrichment in the rat spleen as a result of immunodepression by urethan.

Di Marco, A. T., Franceschi, C. & Prodi, G., Jul 1972, In : Cancer Research. 32, 7, p. 1569-1573 5 p.

Research output: Contribution to journalArticle

Selective effect on T and B cell subpopulations in rat lymphoid organs after urethan treatment

Franceschi, C., Perocco, P., Paolucci, P. & Prodi, G., 1976, In : International Archives of Allergy and Applied Immunology. 50, 5, p. 513-524 12 p.

Research output: Contribution to journalArticle

Role of toll-like receptor 4 in acute myocardial infarction and longevity [4]

Balistreri, C. R., Candore, G., Colonna-Romano, G., Lio, D., Caruso, M., Hoffmann, E., Franceschi, C. & Caruso, C., Nov 17 2004, In : Journal of the American Medical Association. 292, 19, p. 2339-2340 2 p.

Research output: Contribution to journalArticle

Role of TLR4 receptor polymorphisms in Boutonneuse fever.

Balistreri, C. R., Candore, G., Lio, D., Colonna-Romano, G., Di Lorenzo, G., Mansueto, P., Rini, G., Mansueto, S., Cillari, E., Franceschi, C. & Caruso, C., Oct 2005, In : International Journal of Immunopathology and Pharmacology. 18, 4, p. 655-660 6 p.

Research output: Contribution to journalArticle

Role of the pyrin M694V (A2080G) allele in acute myocardial infarction and longevity: A study in the Sicilian population

Grimaldi, M. P., Candore, G., Vasto, S., Caruso, M., Caimi, G., Hoffmann, E., Colonna-Romano, G., Lio, D., Shinar, Y., Franceschi, C. & Caruso, C., Mar 2006, In : Journal of Leukocyte Biology. 79, 3, p. 611-615 5 p.

Research output: Contribution to journalArticle

Role of polymorphisms of CC-chemokine receptor-5 gene in acute myocardial infarction and biological implications for longevity

Balistreri, C. R., Candore, G., Caruso, M., Incalcaterra, E., Franceschi, C. & Caruso, C., Apr 2008, In : Haematologica. 93, 4, p. 637-638 2 p.

Research output: Contribution to journalArticle

Role of mitochondrial DNA in longevity, aging and age-related diseases in humans: A reappraisal

Sevini, F., Santoro, A., Raule, N., Lescai, F. & Franceschi, C., Dec 2007, In : Italian Journal of Biochemistry. 56, 4, p. 243-253 11 p.

Research output: Contribution to journalArticle

Role of interaction between variants in the PPARG and interleukin-6 genes on obesity related metabolic risk factors

Barbieri, M., Rizzo, M. R., Papa, M., Acampora, R., De Angelis, L., Olivieri, F., Marchegiani, F., Franceschi, C. & Paolisso, G., Jul 2005, In : Experimental Gerontology. 40, 7, p. 599-604 6 p.

Research output: Contribution to journalArticle