• 43854 Citations
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1969 …2019
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Research Output 1969 2019

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Article
2013
11 Citations (Scopus)
Kidney
Hydrolases
Nitric Oxide Synthase
N,N-dimethylarginine
Nitric Oxide Synthase Type III
38 Citations (Scopus)

Circulating levels of adipokines and IGF-1 are associated with skeletal muscle strength of young and old healthy subjects

Bucci, L., Yani, S. L., Fabbri, C., Bijlsma, A. Y., Maier, A. B., Meskers, C. G., Narici, M. V., Jones, D. A., McPhee, J. S., Seppet, E., Gapeyeva, H., Pääsuke, M., Sipilä, S., Kovanen, V., Stenroth, L., Musarò, A., Hogrel, J. Y., Barnouin, Y., Butler-Browne, G., Capri, M. & 2 others, Franceschi, C. & Salvioli, S., Jun 2013, In : Biogerontology. 14, 3, p. 261-272 12 p.

Research output: Contribution to journalArticle

Adipokines
Muscle Strength
Somatomedins
Adiponectin
Healthy Volunteers
27 Citations (Scopus)

Colorectal cancer microenvironment: Among nutrition, gut microbiota, inflammation and epigenetics

Garagnani, P., Pirazzini, C. & Franceschi, C., 2013, In : Current Pharmaceutical Design. 19, 4, p. 765-778 14 p.

Research output: Contribution to journalArticle

Tumor Microenvironment
Epigenomics
Colorectal Neoplasms
Inflammation
Dysbiosis
17 Citations (Scopus)

Definition of miRNAs Expression Profile in Glioblastoma Samples: The Relevance of Non-Neoplastic Brain Reference

Visani, M., de Biase, D., Marucci, G., Taccioli, C., Baruzzi, A., Pession, A., Baruzzi, A., Albani, F., Calbucci, F., D'Alessandro, R., Michelucci, R., Brandes, A., EusebiEusebi, V., Ceruti, S., Fainardi, E., Tamarozzi, R., Emiliani, E., Cavallo, M., Franceschi, E., Tosoni, A. & 124 others, Cavallo, M., Fiorica, F., Valentini, A., Depenni, R., Mucciarini, C., Crisi, G., Sasso, E., Biasini, C., Cavanna, L., Guidetti, D., Marcello, N., Pisanello, A., Cremonini, A. M., Guiducci, G., de Pasqua, S., Testoni, S., Agati, R., Ambrosetto, G., Bacci, A., Baldin, E., Baldrati, A., Barbieri, E., Bartolini, S., Bellavista, E., Bisulli, F., Bonora, E., Bunkheila, F., Carelli, V., Crisci, M., Dall'Occa, P., Ferro, S., Franceschi, C., Frezza, G., Grasso, V., Leonardi, M., Mostacci, B., Palandri, G., Pasini, E., Pastore Trossello, M., Poggi, R., Riguzzi, P., Rinaldi, R., Rizzi, S., Romeo, G., Spagnolli, F., Tinuper, P., Trocino, C., Cerasoli, S., Dall'Agata, M., Faedi, M., Frattarelli, M., Gentili, G., Giovannini, A., Iorio, P., Pasquini, U., Galletti, G., Guidi, C., Neri, W., Patuelli, A., Strumia, S., Casmiro, M., Gamboni, A., Rasi, F., Cruciani, G., Cenni, P., Dazzi, C., Guidi, A. R., Zumaglini, F., Amadori, A., Pasini, G., Pasquinelli, M., Pasquini, E., Polselli, A., Ravasio, A., Viti, B., Sintini, M., Ariatti, A., Bertolini, F., Bigliardi, G., Carpeggiani, P., Cavalleri, F., Meletti, S., Nichelli, P., Pettorelli, E., Pinna, G., Zunarelli, E., Artioli, F., Bernardini, I., Costa, M., Greco, G., Guerzoni, R., Stucchi, C., Iaccarino, C., Ragazzi, M., Rizzi, R., Zuccoli, G., Api, P., Cartei, F., Fallica, E., Granieri, E., Latini, F., Lelli, G., Monetti, C., Saletti, A., Schivalocchi, R., Seraceni, S., Tola, M. R., Urbini, B., Giorgi, C., Montanari, E., Cerasti, D., Crafa, P., Dascola, I., Florindo, I., Giombelli, E., Mazza, S., Ramponi, V., Servadei, F., Silini, E. M., Torelli, P., Immovilli, P., Morelli, N., Vanzo, C. & Nobile, C., Jan 29 2013, In : PLoS One. 8, 1, e55314.

Research output: Contribution to journalArticle

Glioblastoma
MicroRNAs
Brain
brain
neoplasms
21 Citations (Scopus)

Does the longevity of one or both parents influence the health status of their offspring?

Gueresi, P., Miglio, R., Monti, D., Mari, D., Sansoni, P., Caruso, C., Bonafede, E., Bucci, L., Cevenini, E., Ostan, R., Palmas, M. G., Pini, E., Scurti, M. & Franceschi, C., Apr 2013, In : Experimental Gerontology. 48, 4, p. 395-400 6 p.

Research output: Contribution to journalArticle

Health Status
Parents
Health
Pathology
Demography
104 Citations (Scopus)

Functional metagenomic profiling of intestinal microbiome in extreme ageing

Rampelli, S., Candela, M., Turroni, S., Collino, E. B., Franceschi, C., O'Toole, P. W. & Brigidi, P., Dec 2013, In : Aging. 5, 12, p. 902-912 11 p.

Research output: Contribution to journalArticle

Metagenomics
Metagenome
Microbial Genes
Bacteria
Bacterial DNA
107 Citations (Scopus)

Genome-wide linkage analysis for human longevity: Genetics of healthy aging study

Beekman, M., Blanché, H., Perola, M., Hervonen, A., Bezrukov, V., Sikora, E., Flachsbart, F., Christiansen, L., De Craen, A. J. M., Kirkwood, T. B. L., Rea, I. M., Poulain, M., Robine, J. M., Valensin, S., Stazi, M. A., Passarino, G., Deiana, L., Gonos, E. S., Paternoster, L., Sørensen, T. I. A. & 20 others, Tan, Q., Helmer, Q., Van Den Akker, E. B., Deelen, J., Martella, F., Cordell, H. J., Ayers, K. L., Vaupel, J. W., Törnwall, O., Johnson, T. E., Schreiber, S., Lathrop, M., Skytthe, A., Westendorp, R. G. J., Christensen, K., Gampe, J., Nebel, A., Houwing-Duistermaat, J. J., Slagboom, P. E. & Franceschi, C., 2013, In : Aging Cell. 12, 2, p. 184-193 10 p.

Research output: Contribution to journalArticle

Medical Genetics
Genome
Chromosomes
Alleles
Genes
55 Citations (Scopus)

HAPLOFIND: A new method for high-throughput mtDNA haplogroup assignment

Vianello, D., Sevini, F., Castellani, G., Lomartire, L., Capri, M. & Franceschi, C., Sep 2013, In : Human Mutation. 34, 9, p. 1189-1194 6 p.

Research output: Contribution to journalArticle

Mitochondrial DNA
Nucleic Acid Databases
Terminology
High-Throughput Nucleotide Sequencing
Genomics
21 Citations (Scopus)

High-resolution quantitative metabolome analysis of urine by automated flow injection NMR

Da Silva, L., Godejohann, M., Martin, F. P. J., Collino, S., Bürkle, A., Moreno-Villanueva, M., Bernhardt, J., Toussaint, O., Grubeck-Loebenstein, B., Gonos, E. S., Sikora, E., Grune, T., Breusing, N., Franceschi, C., Hervonen, A., Spraul, M. & Moco, S., Jun 18 2013, In : Analytical Chemistry. 85, 12, p. 5801-5809 9 p.

Research output: Contribution to journalArticle

Metabolism
Nuclear magnetic resonance
Metabolites
Chemical analysis
Health
6 Citations (Scopus)

How to classify the oldest old according to their health status: A study on 1160 subjects belonging to 552 90+ Italian sib-ships characterized by familial longevity recruited within the GEHA EU Project

Cevenini, E., Cotichini, R., Stazi, M. A., Toccaceli, V., Scurti, M., Mari, V., Berardelli, M., Passarino, G., Jeune, B., Franceschi, C., Bezrukov, V., Blanché, H., Bolund, L., Christensen, K., Deiana, L., Gonos, E., Hervonen, A., Kirkwood, T. B. L., Kristensen, P., Leon, A. & 12 others, Pelicci, P. G., Perola, M., Poulain, M., Rea, I. M., Remacle, J., Robine, J. M., Schreiber, S., Sikora, E., Slagboom, P. E., Spazzafumo, L., Toussaint, O. & Vaupel, J. W., 2013, In : Mechanisms of Ageing and Development. 134, 11-12, p. 560-569 10 p.

Research output: Contribution to journalArticle

Ships
Italy
Health Status
Healthy Volunteers
Survival
63 Citations (Scopus)

Identifying the genomic determinants of aging and longevity in human population studies: Progress and challenges

Deelen, J., Beekman, M., Capri, M., Franceschi, C. & Slagboom, P. E., Apr 2013, In : BioEssays. 35, 4, p. 386-396 11 p.

Research output: Contribution to journalArticle

Genes
Aging of materials
Biomarkers
Technology
Medical Genetics
94 Citations (Scopus)

Immune system, cell senescence, aging and longevity - inflamm-aging reappraised

Salvioli, S., Monti, D., Lanzarini, C., Conte, M., Pirazzini, C., Bacalini, M. G., Garagnani, P., Giuliani, C., Fontanesi, E., Ostan, R., Bucci, L., Sevini, F., Yani, S. L., Barbieri, A., Lomartire, L., Borelli, V., Vianello, D., Bellavista, E., Martucci, M., Cevenini, E. & 6 others, Pini, E., Scurti, M., Biondi, F., Santoro, A., Capri, M. & Franceschi, C., 2013, In : Current Pharmaceutical Design. 19, 9, p. 1675-1679 5 p.

Research output: Contribution to journalArticle

Cell Aging
Immune System
Inflammation
Immunosenescence
23 Citations (Scopus)

Immunoproteasome in cancer and neuropathologies: A new therapeutic target?

Bellavista, E., Andreoli, F., Parenti, M. D., Martucci, M., Santoro, A., Salvioli, S., Capri, M., Baruzzi, A., Del Rio, A., Franceschi, C. & Mishto, M., 2013, In : Current Pharmaceutical Design. 19, 4, p. 702-718 17 p.

Research output: Contribution to journalArticle

Proteasome Endopeptidase Complex
Neoplasms
Pharmaceutical Chemistry
Central Nervous System Diseases
Antigen Presentation
29 Citations (Scopus)

Increased Plin2 Expression in Human Skeletal Muscle Is Associated with Sarcopenia and Muscle Weakness

Conte, M., Vasuri, F., Trisolino, G., Bellavista, E., Santoro, A., Degiovanni, A., Martucci, E., D'Errico-Grigioni, A., Caporossi, D., Capri, M., Maier, A. B., Seynnes, O., Barberi, L., Musarò, A., Narici, M. V., Franceschi, C. & Salvioli, S., Aug 15 2013, In : PLoS One. 8, 8, e73709.

Research output: Contribution to journalArticle

sarcopenia
Sarcopenia
Muscle Weakness
Muscle Strength
Insulin-Like Growth Factor I
141 Citations (Scopus)

Inflamm-ageing

Cevenini, E., Monti, D. & Franceschi, C., Jan 2013, In : Current Opinion in Clinical Nutrition and Metabolic Care. 16, 1, p. 14-20 7 p.

Research output: Contribution to journalArticle

Health Status
Inflammation
Biological Factors
Pathology
Population
98 Citations (Scopus)

Metabolic Signatures of Extreme Longevity in Northern Italian Centenarians Reveal a Complex Remodeling of Lipids, Amino Acids, and Gut Microbiota Metabolism

Collino, S., Montoliu, I., Martin, F. P. J., Scherer, M., Mari, D., Salvioli, S., Bucci, L., Ostan, R., Monti, D., Biagi, E., Brigidi, P., Franceschi, C. & Rezzi, S., Mar 6 2013, In : PLoS One. 8, 3, e56564.

Research output: Contribution to journalArticle

intestinal microorganisms
Metabolism
Aging of materials
Lipids
Amino Acids
17 Citations (Scopus)

Metabolic syndrome in the offspring of centenarians: Focus on prevalence, components, and adipokines

Ostan, R., Bucci, L., Cevenini, E., Palmas, M. G., Pini, E., Scurti, M., Vescovini, R., Caruso, C., Mari, D., Vitale, G., Franceschi, C. & Monti, D., Oct 2013, In : Age. 35, 5, p. 1995-2007 13 p.

Research output: Contribution to journalArticle

Adipokines
Resistin
Insulin-Like Growth Factor I
Dyslipidemias
Cluster Analysis
103 Citations (Scopus)

MicroRNAs linking inflamm-aging, cellular senescence and cancer

Olivieri, F., Rippo, M. R., Monsurrò, V., Salvioli, S., Capri, M., Procopio, A. D. & Franceschi, C., Sep 2013, In : Ageing Research Reviews. 12, 4, p. 1056-1068 13 p.

Research output: Contribution to journalArticle

Cell Aging
MicroRNAs
Aging of materials
Neoplasms
Inflammation
109 Citations (Scopus)

MiR-146a as marker of senescence-Associated pro-inflammatory status in cells involved in vascular remodelling

Olivieri, F., Lazzarini, R., Recchioni, R., Marcheselli, F., Rippo, M. R., Di Nuzzo, S., Albertini, M. C., Graciotti, L., Babini, L., Mariotti, S., Spada, G., Abbatecola, A. M., Antonicelli, R., Franceschi, C. & Procopio, A. D., Aug 2013, In : Age. 35, 4, p. 1157-1172 16 p.

Research output: Contribution to journalArticle

MicroRNAs
Endothelial Cells
Heart Failure
Telomerase
Telomere
99 Citations (Scopus)

N-glycomic biomarkers of biological aging and longevity: A link with inflammaging

Dall'Olio, F., Vanhooren, V., Chen, C. C., Slagboom, P. E., Wuhrer, M. & Franceschi, C., Mar 2013, In : Ageing Research Reviews. 12, 2, p. 685-698 14 p.

Research output: Contribution to journalArticle

Glycomics
Biomarkers
Immunoglobulin G
Aging of materials
Inflammation
102 Citations (Scopus)

Oxidative stress and the ageing endocrine system

Vitale, G., Salvioli, S. & Franceschi, C., Apr 2013, In : Nature Reviews Endocrinology. 9, 4, p. 228-240 13 p.

Research output: Contribution to journalArticle

Endocrine System
Oxidative Stress
Inflammation
Endocrine Glands
Endocrine System Diseases
19 Citations (Scopus)

Pre-analytical stability of the plasma proteomes based on the storage temperature

Pasella, S., Baralla, A., Canu, E., Pinna, S., Vaupel, J., Deiana, M., Franceschi, C., Baggio, G., Zinellu, A., Sotgia, S., Castaldo, G., Carru, C. & Deiana, L., Mar 21 2013, In : Proteome Science. 11, 1, 10.

Research output: Contribution to journalArticle

Proteome
Plasmas
Temperature
Proteins
Haptoglobins
26 Citations (Scopus)

Remodelling of biological parameters during human ageing: Evidence for complex regulation in longevity and in type 2 diabetes

Spazzafumo, L., Olivieri, F., Abbatecola, A. M., Castellani, G., Monti, D., Lisa, R., Galeazzi, R., Sirolla, C., Testa, R., Ostan, R., Scurti, M., Caruso, C., Vasto, S., Vescovini, R., Ogliari, G., Mari, D., Lattanzio, F. & Franceschi, C., Apr 2013, In : Age. 35, 2, p. 419-429 11 p.

Research output: Contribution to journalArticle

Type 2 Diabetes Mellitus
Healthy Volunteers
Age Groups
Biomarkers
Principal Component Analysis
118 Citations (Scopus)

Role of epigenetics in human aging and longevity: Genome-wide DNA methylation profile in centenarians and centenarians' offspring

Gentilini, D., Mari, D., Castaldi, D., Remondini, D., Ogliari, G., Ostan, R., Bucci, L., Sirchia, S. M., Tabano, S., Cavagnini, F., Monti, D., Franceschi, C., Di Blasio, A. M. & Vitale, G., Oct 2013, In : Age. 35, 5, p. 1961-1973 13 p.

Research output: Contribution to journalArticle

DNA Methylation
Epigenomics
Genome
Methylation
Parents
12 Citations (Scopus)

Slug/β-catenin-dependent proinflammatory phenotype in hypoxic breast cancer stem cells

Storci, G., Bertoni, S., De Carolis, S., Papi, A., Nati, M., Ceccarelli, C., Pirazzini, C., Garagnani, P., Ferrarini, A., Buson, G., Delledonne, M., Fiorentino, M., Capizzi, E., Gruppioni, E., Taffurelli, M., Santini, D., Franceschi, C., Bandini, G., Bonifazi, F. & Bonafé, M., Nov 2013, In : American Journal of Pathology. 183, 5, p. 1688-1697 10 p.

Research output: Contribution to journalArticle

Catenins
Gastropoda
Neoplastic Stem Cells
Breast Neoplasms
Phenotype
12 Citations (Scopus)

The onset of type 2 diabetes: Proposal for a multi-scale model

Castiglione, F., Tieri, P., De Graaf, A., Franceschi, C., Liò, P., Van Ommen, B., Mazzà, C., Tuchel, A., Bernaschi, M., Samson, C., Colombo, T., Castellani, G. C., Capri, M., Garagnani, P., Salvioli, S., Nguyen, V. A., Bobeldijk-Pastorova, I., Krishnan, S., Cappozzo, A., Sacchetti, M. & 2 others, Morettini, M. & Ernst, M., Oct 2013, In : Journal of Medical Internet Research. 15, 10, 2854.

Research output: Contribution to journalArticle

Type 2 Diabetes Mellitus
Immune System
Nutrigenomics
Genetic Models
European Union
15 Citations (Scopus)

The p53 codon 72 (Arg72Pro) polymorphism is associated with the degree of insulin resistance in type 2 diabetic subjects: A cross-sectional study

Bonfigli, A. R., Sirolla, C., Testa, R., Cucchi, M., Spazzafumo, L., Salvioli, S., Ceriello, A., Olivieri, F., Festa, R., Procopio, A. D., Brandoni, G., Boemi, M., Marra, M. & Franceschi, C., Jun 2013, In : Acta Diabetologica. 50, 3, p. 429-436 8 p.

Research output: Contribution to journalArticle

Codon
Insulin Resistance
Fasting
Cross-Sectional Studies
Genotype
2012
18 Citations (Scopus)

Activity of mannose-binding lectin in centenarians

Tomaiuolo, R., Ruocco, A., Salapete, C., Carru, C., Baggio, G., Franceschi, C., Zinellu, A., Vaupel, J., Bellia, C., Sasso, B. L., Ciaccio, M., Castaldo, G. & Deiana, L., Jun 2012, In : Aging Cell. 11, 3, p. 394-400 7 p.

Research output: Contribution to journalArticle

Mannose-Binding Lectin
Haplotypes
Italy
Population
Islands
29 Citations (Scopus)
Allelic Imbalance
X Chromosome Inactivation
Parents
Theoretical Models
DNA
40 Citations (Scopus)

Aged-related increase of high sensitive Troponin T and its implication in acute myocardial infarction diagnosis of elderly patients

Olivieri, F., Galeazzi, R., Giavarina, D., Testa, R., Abbatecola, A. M., Çeka, A., Tamburrini, P., Busco, F., Lazzarini, R., Monti, D., Franceschi, C., Procopio, A. D. & Antonicelli, R., May 2012, In : Mechanisms of Ageing and Development. 133, 5, p. 300-305 6 p.

Research output: Contribution to journalArticle

Troponin T
Myocardial Infarction
Population
Geriatrics
Creatinine
184 Citations (Scopus)

Ageing of the human metaorganism: The microbial counterpart

Biagi, E., Candela, M., Fairweather-Tait, S., Franceschi, C. & Brigidi, P., Feb 2012, In : Age. 34, 1, p. 247-267 21 p.

Research output: Contribution to journalArticle

Prebiotics
Probiotics
Ecosystem
Gastrointestinal Tract
Life Style
131 Citations (Scopus)

Age-related differences in the expression of circulating microRNAs: miR-21 as a new circulating marker of inflammaging

Olivieri, F., Spazzafumo, L., Santini, G., Lazzarini, R., Albertini, M. C., Rippo, M. R., Galeazzi, R., Abbatecola, A. M., Marcheselli, F., Monti, D., Ostan, R., Cevenini, E., Antonicelli, R., Franceschi, C. & Procopio, A. D., Nov 2012, In : Mechanisms of Ageing and Development. 133, 11-12, p. 675-685 11 p.

Research output: Contribution to journalArticle

MicroRNAs
Cardiovascular Diseases
Biomarkers
C-Reactive Protein
Fibrinogen
46 Citations (Scopus)

Charting the NF-κB pathway interactome map

Tieri, P., Termanini, A., Bellavista, E., Salvioli, S., Capri, M. & Franceschi, C., Mar 5 2012, In : PLoS One. 7, 3, e32678.

Research output: Contribution to journalArticle

inflammation
Chemical activation
protein-protein interactions
regulator genes
physiological response
70 Citations (Scopus)

Identification of germline susceptibility loci in ETV6-RUNX1-rearranged childhood acute lymphoblastic leukemia

Ellinghaus, E., Stanulla, M., Richter, G., Ellinghaus, D., Te Kronnie, G., Cario, G., Cazzaniga, G., Horstmann, M., Panzer Grümayer, R., Cavé, H., Trka, J., Cinek, O., Teigler-Schlegel, A., Elsharawy, A., Häsler, R., Nebel, A., Meissner, B., Bartram, T., Lescai, F., Franceschi, C. & 7 others, Giordan, M., Nürnberg, P., Heinzow, B., Zimmermann, M., Schreiber, S., Schrappe, M. & Franke, A., May 2012, In : Leukemia. 26, 5, p. 902-909 8 p.

Research output: Contribution to journalArticle

Precursor Cell Lymphoblastic Leukemia-Lymphoma
Single Nucleotide Polymorphism
Genome
Genetic Translocation
Austria
54 Citations (Scopus)
Stem Cell Niche
Stem cells
Aging of materials
Breast Neoplasms
Cytokines
57 Citations (Scopus)

Low circulating IGF-I bioactivity is associated with human longevity: Findings in centenarians' offspring

Vitale, G., Brugts, M. P., Ogliari, G., Castaldi, D., Fatti, L. M., Varewijck, A. J., Lamberts, S. W., Monti, D., Bucci, L., Cevenini, E., Cavagnini, F., Franceschi, C., Hofland, L. J., Mari, D. & Janssen, J. A. M. J. L., 2012, In : Aging. 4, 9, p. 580-589 10 p.

Research output: Contribution to journalArticle

Insulin-Like Growth Factor I
IGF Type 1 Receptor
Insulin-Like Growth Factor Binding Protein 3
Insulin-Like Growth Factor II
Phosphotransferases
156 Citations (Scopus)

Methylation of ELOVL2 gene as a new epigenetic marker of age

Garagnani, P., Bacalini, M. G., Pirazzini, C., Gori, D., Giuliani, C., Mari, D., Di Blasio, A. M., Gentilini, D., Vitale, G., Collino, S., Rezzi, S., Castellani, G., Capri, M., Salvioli, S. & Franceschi, C., Dec 2012, In : Aging Cell. 11, 6, p. 1132-1134 3 p.

Research output: Contribution to journalArticle

Epigenomics
Methylation
Biomarkers
CpG Islands
Fetal Blood
24 Citations (Scopus)

miRNAs expression analysis in paired fresh/Frozen and dissected formalin fixed and paraffin embedded glioblastoma using real-time PCR

de Biase, D., Visani, M., Morandi, L., Marucci, G., Taccioli, C., Cerasoli, S., Baruzzi, A., Pession, A., Baruzzi, A., Albani, F., Calbucci, F., D'Alessandro, R., Michelucci, R., Brandes, A., Eusebi, V., Ceruti, S., Fainardi, E., Tamarozzi, R., Emiliani, E., Cavallo, M. & 125 others, Franceschi, E., Tosoni, A., Cavallo, M., Fiorica, F., Valentini, A., Depenni, R., Mucciarini, C., Crisi, G., Sasso, E., Biasini, C., Cavanna, L., Guidetti, D., Marcello, N., Pisanello, A., Cremonini, A. M., Guiducci, G., de Pasqua, S., Testoni, S., Agati, R., Ambrosetto, G., Bacci, A., Baldin, E., Baldrati, A., Barbieri, E., Bartolini, S., Bellavista, E., Bisulli, F., Bonora, E., Bunkheila, F., Carelli, V., Crisci, M., Dall'Occa, P., Ferro, S., Franceschi, C., Frezza, G., Grasso, V., Leonardi, M., Mostacci, B., Palandri, G., Pasini, E., Pastore Trossello, M., Poggi, R., Riguzzi, P., Rinaldi, R., Rizzi, S., Romeo, G., Spagnolli, F., Tinuper, P., Trocino, C., Dall'Agata, M., Faedi, M., Frattarelli, M., Gentili, G., Giovannini, A., Iorio, P., Pasquini, U., Galletti, G., Guidi, C., Neri, W., Patuelli, A., Strumia, S., Casmiro, M., Gamboni, A., Rasi, F., Cruciani, G., Cenni, P., DazziDazzi, C., Guidi, A. R., Zumaglini, F., Amadori, A., Pasini, G., Pasquinelli, M., Pasquini, E., Polselli, A., Ravasio, A., Viti, B., Sintini, M., Ariatti, A., Bertolini, F., Bigliardi, G., Carpeggiani, P., Cavalleri, F., Meletti, S., Nichelli, P., Pettorelli, E., Pinna, G., Zunarelli, E., Artioli, F., Bernardini, I., Costa, M., Greco, G., Guerzoni, R., Stucchi, C., Iaccarino, C., Ragazzi, M., Rizzi, R., Zuccoli, G., Api, P., Cartei, F., Fallica, E., Granieri, E., Latini, F., Lelli, G., Monetti, C., Saletti, A., Schivalocchi, R., Seraceni, S., Tola, M. R., Urbini, B., Giorgi, C., Montanari, E., Cerasti, D., Crafa, P., Dascola, I., Florindo, I., Giombelli, E., Mazza, S., Ramponi, V., Servadei, F., Silini, E. M., Torelli, P., Immovilli, P., Morelli, N., Vanzo, C. & Nobile, C., Apr 18 2012, In : PLoS One. 7, 4, e35596.

Research output: Contribution to journalArticle

Glioblastoma
MicroRNAs
formalin
Paraffin
alkanes
3 Citations (Scopus)

Morpho-functional changes of fat body in bacteria fed Drosophila melanogaster strains

Franchini, A., Mandrioli, M., Franceschi, C. & Ottaviani, E., Apr 2012, In : Journal of Molecular Histology. 43, 2, p. 243-251 9 p.

Research output: Contribution to journalArticle

Fat Body
Drosophila melanogaster
Bacteria
Diet
Adipocytes
23 Citations (Scopus)

Space/Population and Time/Age in DNA methylatlations and in mono- and di-zygotic twins of different age

Pirazzini, C., Giuliani, C., Bacalini, M. G., Boattini, A., Capri, M., Fontanesi, E., Marasco, E., Mantovani, V., Pierini, M., Pini, E., Luiselli, D., Franceschi, C. & Garagnani, P., Jul 2012, In : Aging. 4, 7, p. 509-520 12 p.

Research output: Contribution to journalArticle

DNA Methylation
DNA
Population
Monozygotic Twins
Spatio-Temporal Analysis
6 Citations (Scopus)

Survival features of EBV-stabilized cells from centenarians: Morpho-functional and transcriptomic analyses

Matarrese, P., Tinari, A., Ascione, B., Gambardella, L., Remondini, D., Salvioli, S., Tenedini, E., Tagliafico, E., Franceschi, C. & Malorni, W., Dec 2012, In : Age. 34, 6, p. 1341-1359 19 p.

Research output: Contribution to journalArticle

Human Herpesvirus 4
Survival
Autophagy
Lymphocytes
B-Lymphocytes
5 Citations (Scopus)

The second international conference "genetics of aging and longevity".

Anisimov, V. N., Bartke, A., Barzilai, N., Batin, M. A., Blagosklonny, M. V., Brown-Borg, H., Budovskaya, Y., Campisi, J., Friguet, B., Fraifeld, V., Franceschi, C., Gems, D., Gladyshev, V., Gorbunova, V., Gudkov, A. V., Kennedy, B., Konovalenko, M., Kraemer, B., Moskalev, A., Petropoulos, I. & 10 others, Pasyukova, E., Rattan, S., Rogina, B., Seluanov, A., Shaposhnikov, M., Shmookler Reis, R., Tavernarakis, N., Vijg, J., Yashin, A. & Zimniak, P., May 2012, In : Aging. 4, 5, p. 305-317 13 p.

Research output: Contribution to journalArticle

23 Citations (Scopus)

TP53 codon 72 polymorphism affects accumulation of mtDNA damage in human cells

Altilia, S., Santoro, A., Malagoli, D., Lanzarini, C., Alvarez, J. A. B., Galazzo, G., Porter, D. C., Crocco, P., Rose, G., Passarino, G., Roninson, I. B., Franceschi, C. & Salvioli, S., Jan 2012, In : Aging. 4, 1, p. 28-39 12 p.

Research output: Contribution to journalArticle

Mitochondrial DNA
Codon
DNA Damage
Protein Isoforms
Rotenone
2011

Analisi del metiloma negli ultralongevi e nei loro figli e stato di salute

Translated title of the contribution: Genome-wide dna methylation profiles in centenarians and their offspring reveal features of longevity and healthy ageingMari, D., Gentilini, D., Castaldi, D., Remondini, D., Ogliari, G., Ostan, R., Buci, L., Sirchia, S. M., Tabano, S., Cavagnini, F., Monti, D., Franceschi, C., Di Blasio, A. M. & Vitale, G., Oct 2011, In : Giornale di Gerontologia. 59, 5, p. 273-284 12 p.

Research output: Contribution to journalArticle

Methylation
DNA Methylation
Epigenomics
Genome
CpG Islands
22 Citations (Scopus)

An APOE haplotype associated with decreased 4 expression increases the risk of late onset alzheimer's disease

Lescai, F., Chiamenti, A. M., Codemo, A., Pirazzini, C., D'Agostino, G., Ruaro, C., Ghidoni, R., Benussi, L., Galimberti, D., Esposito, F., Marchegiani, F., Cardelli, M., Olivieri, F., Nacmias, B., Sorbi, S., Tagliavini, F., Albani, D., Boneschi, F. M., Binetti, G., Santoro, A. & 5 others, Forloni, G., Scarpini, E., Crepaldi, G., Gabelli, C. & Franceschi, C., 2011, In : Journal of Alzheimer's Disease. 24, 2, p. 235-245 11 p.

Research output: Contribution to journalArticle

Haplotypes
Alzheimer Disease
Apolipoproteins E
Age of Onset
Italy

Chagas en comunidades originarias del Monte Impenetrable chaqueño, Argentina

Translated title of the contribution: Chagas disease in indigenous communities of the Impenetrable Chaqueño ForestMoretti, E., Castro, I., Franceschi, C. & Basso, B., Nov 2011, In : Salud(i)Ciencia. 18, 7, p. 666-669 4 p.

Research output: Contribution to journalArticle

28 Citations (Scopus)

Design, recruitment, logistics, and data management of the GEHA (Genetics of Healthy Ageing) project

Skytthe, A., Valensin, S., Jeune, B., Cevenini, E., Balard, F., Beekman, M., Bezrukov, V., Blanche, H., Bolund, L., Broczek, K., Carru, C., Christensen, K., Christiansen, L., Collerton, J. C., Cotichini, R., de Craen, A. J. M., Dato, S., Davies, K., De Benedictis, G., Deiana, L. & 38 others, Flachsbart, F., Gampe, J., Gilbault, C., Gonos, E. S., Haimes, E., Hervonen, A., Hurme, M. A., Janiszewska, D., Jylhä, M., Kirkwood, T. B. L., Kristensen, P., Laiho, P., Leon, A., Marchisio, A., Masciulli, R., Nebel, A., Passarino, G., Pelicci, G., Peltonen, L., Perola, M., Poulain, M., Rea, I. M., Remacle, J., Robine, J. M., Schreiber, S., Scurti, M., Sevini, F., Sikora, E., Skouteri, A., Slagboom, P. E., Spazzafumo, L., Stazi, M. A., Toccaceli, V., Toussaint, O., Törnwall, O., Vaupel, J. W., Voutetakis, K. & Franceschi, C., Nov 2011, In : Experimental Gerontology. 46, 11, p. 934-945 12 p.

Research output: Contribution to journalArticle

Information management
Logistics
Aging of materials
Siblings
Genes
10 Citations (Scopus)

Ethical aspects of aging research

Seppet, E., Pääsuke, M., Conte, M., Capri, M. & Franceschi, C., Dec 2011, In : Biogerontology. 12, 6, p. 491-502 12 p.

Research output: Contribution to journalArticle

Research
Research Subjects
Sociology
Population Growth
Social Conditions
50 Citations (Scopus)

Gut microbiota as a candidate for lifespan extension: An ecological/evolutionary perspective targeted on living organisms as metaorganisms

Ottaviani, E., Ventura, N., Mandrioli, M., Candela, M., Franchini, A. & Franceschi, C., Dec 2011, In : Biogerontology. 12, 6, p. 599-609 11 p.

Research output: Contribution to journalArticle

Ecosystem
Symbiosis
Diptera
Immune System
Phenotype
73 Citations (Scopus)

Human intestinal microbiota: Cross-talk with the host and its potential role in colorectal cancer

Candela, M., Guidotti, M., Fabbri, A., Brigidi, P., Franceschi, C. & Fiorentini, C., Feb 2011, In : Critical Reviews in Microbiology. 37, 1, p. 1-14 14 p.

Research output: Contribution to journalArticle

Colorectal Neoplasms
Diet
Microbiota
Immunization
Health