Cristina Agliardi &ndash; Research Output

2020

Blood extracellular vesicles (EVs) of central nervous system origin: A window into the brain

Agliardi, C. & Clerici, M., Jan 1 2020, In : Neural Regeneration Research. 15, 1, p. 55-56 2 p.

Research output: Contribution to journal › Review article

Open Access

2019

HLA-G allelic distribution in Sardinian children with Autism spectrum disorders: A replication study

Guerini, F. R., Bolognesi, E., Sotgiu, S., Carta, A., Clerici, C., Chiappedi, M., Ghezzo, A., Zanette, M., Mensi, M. M., Canevini, M. P., Zanzottera, M., Agliardi, C., Costa, A. S., Balottin, U. & Clerici, M., Jan 1 2019, In : Brain, Behavior, and Immunity.

Research output: Contribution to journal › Article

HLA-G Antigens

Alleles

Autism Spectrum Disorder

Population

Myeloid Leukemia

HLA-G allelic distribution in Sardinian children with Autism spectrum disorders: A replication study

Guerini, F. R., Bolognesi, E., Sotgiu, S., Carta, A., Clerici, C., Chiappedi, M., Ghezzo, A., Zanette, M., Mensi, M. M., Canevini, M. P., Zanzottera, M., Agliardi, C., Costa, A. S., Balottin, U. & Clerici, M., Jun 11 2019, In : Brain, Behavior, and Immunity. 79:, p. 314-318 5 p.

Research output: Contribution to journal › Article

HLA-G Antigens

Alleles

Autism Spectrum Disorder

Population

Myeloid Leukemia

HLA-G allelic distribution in Sardinian children with Autism spectrum disorders: A replication study

Guerini, F. R., Bolognesi, E., Sotgiu, S., Carta, A., Clerici, C., Chiappedi, M., Ghezzo, A., Zanette, M., Mensi, M. M., Canevini, M. P., Zanzottera, M., Agliardi, C., Costa, A. S., Balottin, U. & Clerici, M., Jan 1 2019, In : Brain, Behavior, and Immunity.

Research output: Contribution to journal › Article

HLA-G Antigens

Alleles

Autism Spectrum Disorder

Population

Myeloid Leukemia

1 Citation (Scopus)

Multiple sclerosis genomic map implicates peripheral immune cells and microglia in susceptibility

International Multiple Sclerosis Genetics Consortium & ANZgene, IIBDGC, WTCCC2, Sep 27 2019, In : Science. 365, 6460, eaav7188.

Research output: Contribution to journal › Article

Microglia

Multiple Sclerosis

Major Histocompatibility Complex

X Chromosome

Genes

Multiple sclerosis genomic map implicates peripheral immune cells and microglia in susceptibility

Consortium, I. M. S. G., ANZgene IIBDGC, WTCCC., Patsopoulos, N. A., Baranzini, S. E., Santaniello, A., Shoostari, P., Cotsapas, C., Wong, G., Beecham, A. H., James, T., Replogle, J., Vlachos, I. S., McCabe, C., Pers, T. H., Brandes, A., White, C., Keenan, B., Cimpean, M., Winn, P., Panteliadis, I. P. & 32 others, Robbins, A., Andlauer, T. F. M., Zarzycki, O., Dubois, B., Goris, A., Søndergaard, H. B., Sellebjerg, F., Sorensen, P. S., Ullum, H., Thørner, L. W., Saarela, J., Cournu-Rebeix, I., Damotte, V., Fontaine, B., Guillot-Noel, L., Lathrop, M., Vukusic, S., Berthele, A., Agliardi, C., Clarelli, F., Comi, G., Esposito, F., Ferrè, L., Galimberti, D., Leone, M. A., Martinelli, V., Moiola, L., Salvetti, M., Sorosina, M., Santoro, S., Mancini, N. & Martinelli-Boneschi, F., Sep 27 2019, In : Science. 365, 6460

Research output: Contribution to journal › Article

Microglia

Multiple Sclerosis

Major Histocompatibility Complex

X Chromosome

Genes

Multiple sclerosis genomic map implicates peripheral immune cells and microglia in susceptibility

Patsopoulos, N. A., Baranzini, S. E., Santaniello, A., Shoostari, P., Cotsapas, C., Wong, G., Beecham, A. H., James, T., Replogle, J., Vlachos, I. S., McCabe, C., Pers, T. H., Brandes, A., White, C., Keenan, B., Cimpean, M., Winn, P., Panteliadis, I-P., Robbins, A., Andlauer, T. F. M. & 136 others, Zarzycki, O., Dubois, B., Goris, A., Søndergaard, H. B., Sellebjerg, F., Sorensen, P. S., Ullum, H., Thørner, L. W., Saarela, J., Cournu-Rebeix, I., Damotte, V., Fontaine, B., Guillot-Noel, L., Lathrop, M., Vukusic, S., Berthele, A., Pongratz, V., Buck, D., Gasperi, C., Graetz, C., Grummel, V., Hemmer, B., Hoshi, M., Knier, B., Korn, T., Lill, C. M., Luessi, F., Mühlau, M., Zipp, F., Dardiotis, E., Agliardi, C., Amoroso, A., Barizzone, N., Benedetti, M. D., Bernardinelli, L., Cavalla, P., Clarelli, F., Comi, G., Cusi, D., Esposito, F., Ferrè, L., Galimberti, D., Guaschino, C., Leone, M. A., Martinelli, V., Moiola, L., Salvetti, M., Sorosina, M., Vecchio, D., Zauli, A., Santoro, S., Mancini, N., Zuccalà, M., Mescheriakova, J., Van Duijn, C., Bos, S. D., Celius, E. G., Spurkland, A., Comabella, M., Montalban, X., Alfredsson, L., Bomfim, I. L., Gomez-Cabrero, D., Hillert, J., Jagodic, M., Lindén, M., Piehl, F., Jelčić, I., Martin, R., Sospedra, M., Baker, A., Ban, M., Hawkins, C., Hysi, P., Kalra, S., Karpe, F., Khadake, J., Lachance, G., Molyneux, P., Neville, M., Thorpe, J., Bradshaw, E., Caillier, S. J., Calabresi, P., Cree, B. A. C., Cross, A., Davis, M., De Bakker, P. W. I., Delgado, S., Dembele, M., Edwards, K., Fitzgerald, K., Frohlich, I. Y., Gourraud, P-A., Haines, J. L., Hakonarson, H., Kimbrough, D., Isobe, N., Konidari, I., Lathi, E., Lee, M. H., Li, T., An, D., Zimmer, A., Madireddy, L., Manrique, C. P., Mitrovic, M., Olah, M., Patrick, E., Pericak-Vance, M. A., Piccio, L., Schaefer, C., Weiner, H., Lage, K., Compston, A., Hafler, D., Harbo, H. F., Hauser, S. L., Stewart, G., D’Alfonso, S., Hadjigeorgiou, G., Taylor, B., Barcellos, L. F., Booth, D., Hintzen, R., Kockum, I., Martinelli-Boneschi, F., McCauley, J. L., Oksenberg, J. R., Oturai, A., Sawcer, S., Ivinson, A. J., Olsson, T., De Jager, P. L., Consortium, I. M. S. G. & ANZgene IIBDGC, WTCCC., 2019, In : Science. 365, 6460

Research output: Contribution to journal › Article

SNAP25 Gene Polymorphisms Protect Against Parkinson's Disease and Modulate Disease Severity in Patients

Agliardi, C., Guerini, F. R., Zanzottera, M., Riboldazzi, G., Zangaglia, R., Sturchio, A., Casali, C., Di Lorenzo, C., Minafra, B., Nemni, R. & Clerici, M., Jun 2019, In : Molecular Neurobiology. 56, 6, p. 4455-4463 9 p.

Research output: Contribution to journal › Article

Parkinson Disease

SNARE Proteins

Single Nucleotide Polymorphism

Genes

Synucleins

1 Citation (Scopus)

SNAP-25 in Serum Is Carried by Exosomes of Neuronal Origin and Is a Potential Biomarker of Alzheimer’s Disease

Agliardi, C., Guerini, F. R., Zanzottera, M., Bianchi, A., Nemni, R. & Clerici, M., Aug 15 2019, In : Molecular Neurobiology. 56, 8, p. 5792-5798 7 p.

Research output: Contribution to journal › Article

Synaptosomal-Associated Protein 25

Exosomes

Alzheimer Disease

Biomarkers

Serum

The Syntaxin-1A gene single nucleotide polymorphism rs4717806 associates with the risk of ischemic heart disease

Guerini, F. R., Ripamonti, E., Costa, A. S., Zanzottera, M., Agliardi, C., Bolognesi, E., Clerici, M. & Racca, V., Jun 1 2019, In : Medicine. 98, 24, p. e15846

Research output: Contribution to journal › Article

Open Access

Syntaxin 1

Myocardial Ischemia

Single Nucleotide Polymorphism

Genes

Insulin Resistance

2018

3 Citations (Scopus)

HLA alleles modulate EBV viral load in multiple sclerosis

Agostini, S., Mancuso, R., Guerini, F. R., D'Alfonso, S., Agliardi, C., Hernis, A., Zanzottera, M., Barizzone, N., Leone, M. A., Caputo, D., Rovaris, M. & Clerici, M., Mar 27 2018, In : Journal of Translational Medicine. 16, 1, 80.

Research output: Contribution to journal › Article

HLA Antigens

Viral Load

Human Herpesvirus 4

Viruses

Multiple Sclerosis

HLA-G coding region polymorphism is skewed in autistic spectrum disorders

Guerini, F. R., Bolognesi, E., Chiappedi, M., Ripamonti, E., Ghezzo, A., Zanette, M., Sotgiu, S., Mensi, M. M., Carta, A., Canevini, M. P., Zanzottera, M., Agliardi, C., Costa, A. S., Balottin, U. & Clerici, M., Jan 2018, In : Brain, Behavior, and Immunity. 67, p. 308-313 6 p.

Research output: Contribution to journal › Article

HLA-G Antigens

Autistic Disorder

Habitual Abortion

Control Groups

Mothers

HLA-G∗14bp Insertion and the KIR2DS1-HLAC2 Complex Impact on Behavioral Impairment in Children with Autism Spectrum Disorders

Guerini, F. R., Bolognesi, E., Chiappedi, M., Ghezzo, A., Manca, S., Zanette, M., Sotgiu, S., Mensi, M. M., Zanzottera, M., Agliardi, C., Costa, A. S., Balottin, U. & Clerici, M., Feb 1 2018, In : Neuroscience. 370, p. 163-169 7 p.

Research output: Contribution to journal › Article

HLA-C Antigens

Italy

Autistic Disorder

Fetal Development

Electrophoresis

14 Citations (Scopus)

Low-Frequency and Rare-Coding Variation Contributes to Multiple Sclerosis Risk

International Multiple Sclerosis Genetics Consortium, Nov 29 2018, In : Cell. 175, 6, p. 1679-1687.e7

Research output: Contribution to journal › Article

Multiple Sclerosis

Genes

Genome-Wide Association Study

Linkage Disequilibrium

Regulatory T-Lymphocytes

1 Citation (Scopus)

SNAP25 Gene Polymorphisms Protect Against Parkinson’s Disease and Modulate Disease Severity in Patients

Agliardi, C., Guerini, F. R., Zanzottera, M., Riboldazzi, G., Zangaglia, R., Sturchio, A., Casali, C., Di Lorenzo, C., Minafra, B., Nemni, R. & Clerici, M., Jan 1 2018, (Accepted/In press) In : Molecular Neurobiology.

Research output: Contribution to journal › Article

Parkinson Disease

SNARE Proteins

Single Nucleotide Polymorphism

Genes

Synucleins

TNF-α -308 G/A and -238 G/A promoter polymorphisms and sporadic Parkinson's disease in an Italian cohort

Agliardi, C., Guerini, F. R., Zanzottera, M., Riboldazzi, G., Zangaglia, R., Bono, G., Casali, C., Di Lorenzo, C., Pacchetti, C., Nemni, R. & Clerici, M., Feb 15 2018, In : Journal of the Neurological Sciences. 385, p. 45-48 4 p.

Research output: Contribution to journal › Article

Parkinson Disease

Single Nucleotide Polymorphism

Microglia

Age of Onset

England

1 Citation (Scopus)

TNF-α − 308 G/A and − 238 G/A promoter polymorphisms and sporadic Parkinson's disease in an Italian cohort

Agliardi, C., Guerini, F. R., Zanzottera, M., Riboldazzi, G., Zangaglia, R., Bono, G., Casali, C., Di Lorenzo, C., Pacchetti, C., Nemni, R. & Clerici, M., Feb 15 2018, In : Journal of the Neurological Sciences. 385, p. 45-48 4 p.

Research output: Contribution to journal › Article

Parkinson Disease

Single Nucleotide Polymorphism

Microglia

Age of Onset

England

2017

4 Citations (Scopus)

HLA-G*14bp insertion and the KIR2DS1-HLAC2 complex impact on behavioral impairment in children with Autism Spectrum Disorders

Guerini, F. R., Bolognesi, E., Chiappedi, M., Ghezzo, A., Manca, S., Zanette, M., Sotgiu, S., Mensi, M. M., Zanzottera, M., Agliardi, C., Costa, A. S., Balottin, U. & Clerici, M., Jun 2017, In : Neuroscience.

Research output: Contribution to journal › Article

HLA-G Antigens

HLA-C Antigens

Italy

Autistic Disorder

Fetal Development

4 Citations (Scopus)

HLA-G coding region polymorphism is skewed in autistic spectrum disorders

Guerini, F. R., Bolognesi, E., Chiappedi, M., Ripamonti, E., Ghezzo, A., Zanette, M., Sotgiu, S., Mensi, M. M., Carta, A., Canevini, M. P., Zanzottera, M., Agliardi, C., Costa, A. S., Balottin, U. & Clerici, M., Sep 2017, In : Brain, Behavior, and Immunity.

Research output: Contribution to journal › Article

HLA-G Antigens

Autistic Disorder

Habitual Abortion

Control Groups

Mothers

3 Citations (Scopus)

Indoleamine-2,3-dioxygenase(IDO)2 polymorphisms are not associated with multiple sclerosis in Italians

Agliardi, C., Guerini, F. R., Zanzottera, M., Rovaris, M., Caputo, D. & Clerici, M., Jun 15 2017, In : Journal of the Neurological Sciences. 377, p. 31-34 4 p.

Research output: Contribution to journal › Article

Indoleamine-Pyrrole 2,3,-Dioxygenase

Multiple Sclerosis

Age of Onset

Disease Progression

Enzymes

4 Citations (Scopus)

Vitamin D-binding protein gene polymorphisms are not associated with MS risk in an Italian cohort

Agliardi, C., Guerini, F. R., Zanzottera, M., Bolognesi, E., Costa, A. S. & Clerici, M., Apr 15 2017, In : Journal of Neuroimmunology. 305, p. 92-95 4 p.

Research output: Contribution to journal › Article

Vitamin D-Binding Protein

Multiple Sclerosis

Vitamin D

Genes

Carrier Proteins

2015

15 Citations (Scopus)

An HLA-G^*14bp insertion/deletion polymorphism associates with the development of autistic spectrum disorders

Guerini, F. R., Bolognesi, E., Chiappedi, M., Ghezzo, A., Canevini, M. P., Mensi, M. M., Vignoli, A., Agliardi, C., Zanette, M. & Clerici, M., Feb 1 2015, In : Brain, Behavior, and Immunity. 44, p. 207-212 6 p.

Research output: Contribution to journal › Article

HLA-G Antigens

Autistic Disorder

Immune Tolerance

Mothers

Pregnancy

17 Citations (Scopus)

Epstein-Barr virus genetic variants are associated with multiple sclerosis

Mechelli, R., Manzari, C., Policano, C., Annese, A., Picardi, E., Umeton, R., Fornasiero, A., D'Erchia, A. M., Buscarinu, M. C., Agliardi, C., Annibali, V., Serafini, B., Rosicarelli, B., Romano, S., Angelini, D. F., Ricigliano, V. A. G., Buttari, F., Battistini, L., Centonze, D., Guerini, F. R. & 4 others, D'Alfonso, S., Pesole, G., Salvetti, M. & Ristori, G., Mar 31 2015, In : Neurology. 84, 13, p. 1362-1368 7 p.

Research output: Contribution to journal › Article

Nuclear Antigens

Human Herpesvirus 4

Multiple Sclerosis

Alleles

Tissue Donors

2014

16 Citations (Scopus)

Activating KIR molecules and their cognate ligands prevail in children with a diagnosis of ASD and in their mothers

Guerini, F. R., Bolognesi, E., Chiappedi, M., Manca, S., Ghezzo, A., Agliardi, C., Zanette, M., Littera, R., Carcassi, C., Sotgiu, S. & Clerici, M., Feb 2014, In : Brain, Behavior, and Immunity. 36, p. 54-60 7 p.

Research output: Contribution to journal › Article

Mothers

Ligands

Natural Killer Cells

KIR Receptors

Trophoblasts

19 Citations (Scopus)

Ancient and recent selective pressures shaped genetic diversity at AIM2-like nucleic acid sensors

Cagliani, R., Forni, D., Biasin, M., Comabella, M., Guerini, F. R., Riva, S., Pozzoli, U., Agliardi, C., Caputo, D., Malhotra, S., Montalban, X., Bresolin, N., Clerici, M. & Sironi, M., 2014, In : Genome Biology and Evolution. 6, 4, p. 830-845 16 p.

Research output: Contribution to journal › Article

nucleic acid

Nucleic Acids

nucleic acids

autoimmune diseases

Population Genetics

No association of IFI16 (interferon-inducible protein 16) variants with susceptibility to multiple sclerosis

Guerini, F. R., Clerici, M., Cagliani, R., Malhotra, S., Montalban, X., Forni, D., Agliardi, C., Riva, S., Caputo, D., Galimberti, D., Asselta, R., Fenoglio, C., Scarpini, E., Comi, G. P., Bresolin, N., Comabella, M. & Sironi, M., 2014, In : Journal of Neuroimmunology. 271, 1-2, p. 49-52 4 p.

Research output: Contribution to journal › Article

Interferons

Multiple Sclerosis

Inflammasomes

Proteins

Celiac Disease

19 Citations (Scopus)

Possible association between SNAP-25 single nucleotide polymorphisms and alterations of categorical fluency and functional MRI parameters in Alzheimer's disease

Guerini, F. R., Agliardi, C., Sironi, M., Arosio, B., Calabrese, E., Zanzottera, M., Bolognesi, E., Ricci, C., Costa, A. S., Galimberti, D., Griffanti, L., Bianchi, A., Savazzi, F., Mari, D., Scarpini, E., Baglio, F., Nemni, R. & Clerici, M., 2014, In : Journal of Alzheimer's Disease. 42, 3, p. 1015-1028 14 p.

Research output: Contribution to journal › Article

Synaptosomal-Associated Protein 25

Single Nucleotide Polymorphism

Alzheimer Disease

Magnetic Resonance Imaging

SNARE Proteins

45 Citations (Scopus)

Vitamin D receptor gene polymorphisms are associated with obesity and inflammosome activity

Al-Daghri, N. M., Guerini, F. R., Al-Attas, O. S., Alokail, M. S., Alkharfy, K. M., Draz, H. M., Agliardi, C., Costa, A. S., Saulle, I., Mohammed, A. K., Biasin, M. & Clerici, M., Jul 14 2014, In : PLoS One. 9, 7, e102141.

Research output: Contribution to journal › Article

Calcitriol Receptors

vitamin D

Polymorphism

obesity

Obesity

24 Citations (Scopus)

Whole-blood global DNA methylation is increased in amyotrophic lateral sclerosis independently of age of onset

Tremolizzo, L., Messina, P., Conti, E., Sala, G., Cecchi, M., Airoldi, L., Pastorelli, R., Pupillo, E., Bandettini Di Poggio, M., Filosto, M., Lunetta, C., Agliardi, C., Guerini, F., Mandrioli, J., Calvo, A., Beghi, E., Ferrarese, C. & Consortium, E., 2014, In : Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration. 15, 1-2, p. 98-105 8 p.

Research output: Contribution to journal › Article

Amyotrophic Lateral Sclerosis

DNA Methylation

Age of Onset

Methionine

Homocysteine

2013

646 Citations (Scopus)

Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis

Beecham, A. H., Patsopoulos, N. A., Xifara, D. K., Davis, M. F., Kemppinen, A., Cotsapas, C., Shah, T. S., Spencer, C., Booth, D., Goris, A., Oturai, A., Saarela, J., Fontaine, B., Hemmer, B., Martin, C., Zipp, F., D'Alfonso, S., Martinelli-Boneschi, F., Taylor, B., Harbo, H. F. & 173 others, Kockum, I., Hillert, J., Olsson, T., Ban, M., Oksenberg, J. R., Hintzen, R., Barcellos, L. F., Agliardi, C., Alfredsson, L., Alizadeh, M., Anderson, C., Andrews, R., Søndergaard, H. B., Baker, A., Band, G., Baranzini, S. E., Barizzone, N., Barrett, J., Bellenguez, C., Bergamaschi, L., Bernardinelli, L., Berthele, A., Biberacher, V., Binder, T. M. C., Blackburn, H., Bomfim, I. L., Brambilla, P., Broadley, S., Brochet, B., Brundin, L., Buck, D., Butzkueven, H., Caillier, S. J., Camu, W., Carpentier, W., Cavalla, P., Celius, E. G., Coman, I., Comi, G., Corrado, L., Cosemans, L., Cournu-Rebeix, I., Cree, B. A. C., Cusi, D., Damotte, V., Defer, G., Delgado, S. R., Deloukas, P., Di Sapio, A., Dilthey, A. T., Donnelly, P., Dubois, B., Duddy, M., Edkins, S., Elovaara, I., Esposito, F., Evangelou, N., Fiddes, B., Field, J., Franke, A., Freeman, C., Frohlich, I. Y., Galimberti, D., Gieger, C., Gourraud, P. A., Graetz, C., Graham, A., Grummel, V., Guaschino, C., Hadjixenofontos, A., Hakonarson, H., Halfpenny, C., Hall, G., Hall, P., Hamsten, A., Harley, J., Harrower, T., Hawkins, C., Hellenthal, G., Hillier, C., Hobart, J., Hoshi, M., Hunt, S. E., Jagodic, M., Jelcic, I., Jochim, A., Kendall, B., Kermode, A., Kilpatrick, T., Koivisto, K., Konidari, I., Korn, T., Kronsbein, H., Langford, C., Larsson, M., Lathrop, M., Lebrun-Frenay, C., Lechner-Scott, J., Lee, M. H., Leone, M. A., Leppä, V., Liberatore, G., Lie, B. A., Lill, C. M., Lindén, M., Link, J., Luessi, F., Lycke, J., Macciardi, F., Männistö, S., Manrique, C. P., Martin, R., Martinelli, V., Mason, D., Mazibrada, G., McCabe, C., Mero, I. L., Mescheriakova, J., Moutsianas, L., Myhr, K. M., Nagels, G., Nicholas, R., Nilsson, P., Piehl, F., Pirinen, M., Price, S. E., Quach, H., Reunanen, M., Robberecht, W., Robertson, N. P., Rodegher, M., Rog, D., Salvetti, M., Schnetz-Boutaud, N. C., Sellebjerg, F., Selter, R. C., Schaefer, C., Shaunak, S., Shen, L., Shields, S., Siffrin, V., Slee, M., Sorensen, P. S., Sorosina, M., Sospedra, M., Spurkland, A., Strange, A., Sundqvist, E., Thijs, V., Thorpe, J., Ticca, A., Tienari, P., Van Duijn, C., Visser, E. M., Vucic, S., Westerlind, H., Wiley, J. S., Wilkins, A., Wilson, J. F., Winkelmann, J., Zajicek, J., Zindler, E., Haines, J. L., Pericak-Vance, M. A., Ivinson, A. J., Stewart, G., Hafler, D., Hauser, S. L., Compston, A., McVean, G., De Jager, P., Sawcer, S. J. & McCauley, J. L., Nov 2013, In : Nature Genetics. 45, 11, p. 1353-1362 10 p.

Research output: Contribution to journal › Article

Multiple Sclerosis

Genome-Wide Association Study

Major Histocompatibility Complex

12 Citations (Scopus)

Endoplasmic reticulum aminopeptidase 2 haplotypes play a role in modulating susceptibility to HIV infection

Biasin, M., Sironi, M., Saulle, I., De Luca, M., La Rosa, F., Cagliani, R., Forni, D., Agliardi, C., Caputo, S. L., Mazzotta, F., Trabattoni, D., Macias, J., Pineda, J. A., Caruz, A. & Clerici, M., Jul 17 2013, In : AIDS (London, England). 27, 11, p. 1697-1706 10 p.

Research output: Contribution to journal › Article

Aminopeptidases

Endoplasmic Reticulum

Haplotypes

HIV Infections

HIV-1

5 Citations (Scopus)

Long-Standing Balancing Selection in the THBS4 Gene: Influence on Sex-Specific Brain Expression and Gray Matter Volumes in Alzheimer Disease

Cagliani, R., Guerini, F. R., Rubio-Acero, R., Baglio, F., Forni, D., Agliardi, C., Griffanti, L., Fumagalli, M., Pozzoli, U., Riva, S., Calabrese, E., Sikora, M., Casals, F., Comi, G. P., Bresolin, N., Cáceres, M., Clerici, M. & Sironi, M., May 2013, In : Human Mutation. 34, 5, p. 743-753 11 p.

Research output: Contribution to journal › Article

Alzheimer Disease

Brain

Genes

Gene Expression

Pan troglodytes

2012

Activating KIR/HLA complexes in classic Kaposi's Sarcoma

Guerini, F. R., Mancuso, R., Agostini, S., Agliardi, C., Zanzottera, M., Hernis, A., Tourlaki, A., Calvo, M. G., Bellinvia, M., Brambilla, L. & Clerici, M., 2012, In : Infectious Agents and Cancer. 7, 1, 9.

Research output: Contribution to journal › Article

Human Herpesvirus 8

Kaposi's Sarcoma

Genotype

Ligands

KIR Receptors

40 Citations (Scopus)

A functional variant in ERAP1 predisposes to multiple sclerosis

Guerini, F. R., Cagliani, R., Forni, D., Agliardi, C., Caputo, D., Cassinotti, A., Galimberti, D., Fenoglio, C., Biasin, M., Asselta, R., Scarpini, E., Comi, G. P., Bresolin, N., Clerici, M. & Sironi, M., Jan 12 2012, In : PLoS One. 7, 1, e29931.

Research output: Contribution to journal › Article

Crohn disease

sclerosis

Crohn Disease

Multiple Sclerosis

Spondylitis

15 Citations (Scopus)

A trans-specific polymorphism in ZC3HAV1 is maintained by long-standing balancing selection and may confer susceptibility to multiple sclerosis

Cagliani, R., Guerini, F. R., Fumagalli, M., Riva, S., Agliardi, C., Galimberti, D., Pozzoli, U., Goris, A., Dubois, B., Fenoglio, C., Forni, D., Sanna, S., Zara, I., Pitzalis, M., Zoledziewska, M., Cucca, F., Marini, F., Comi, G. P., Scarpini, E., Bresolin, N. & 2 others, Clerici, M. & Sironi, M., Jun 2012, In : Molecular Biology and Evolution. 29, 6, p. 1599-1613 15 p.

Research output: Contribution to journal › Article

sclerosis

Pan troglodytes

Multiple Sclerosis

polymorphism

genetic polymorphism

14 Citations (Scopus)

Identification of a new susceptibility variant for multiple sclerosis in OAS1 by population genetics analysis

Cagliani, R., Fumagalli, M., Guerini, F. R., Riva, S., Galimberti, D., Comi, G. P., Agliardi, C., Scarpini, E., Pozzoli, U., Forni, D., Caputo, D., Asselta, R., Biasin, M., Paraboschi, E. M., Bresolin, N., Clerici, M. & Sironi, M., Jan 2012, In : Human Genetics. 131, 1, p. 87-97 11 p.

Research output: Contribution to journal › Article

Population Genetics

Multiple Sclerosis

Exons

Genealogy and Heraldry

Disease Susceptibility

23 Citations (Scopus)

Vitamin D receptor gene polymorphisms and HLA DRB1*04 cosegregation in Saudi type 2 diabetes patients

Al-Daghri, N. M., Al-Attas, O., Alokail, M. S., Alkharfy, K. M., Draz, H. M., Agliardi, C., Mohammed, A. K., Guerini, F. R. & Clerici, M., Feb 1 2012, In : Journal of Immunology. 188, 3, p. 1325-1332 8 p.

Research output: Contribution to journal › Article

Calcitriol Receptors

Type 2 Diabetes Mellitus

Genes

Alleles

HLA-DRB1*04 antigen

2011

12 Citations (Scopus)

An evolutionary analysis of RAC2 identifies haplotypes associated with human autoimmune diseases

Sironi, M., Guerini, F. R., Agliardi, C., Biasin, M., Cagliani, R., Fumagalli, M., Caputo, D., Cassinotti, A., Ardizzone, S., Zanzottera, M., Bolognesi, E., Riva, S., Kanari, Y., Miyazawa, M. & Clerici, M., Dec 2011, In : Molecular Biology and Evolution. 28, 12, p. 3319-3329 11 p.

Research output: Contribution to journal › Article

autoimmune diseases

Haplotypes

Autoimmune Diseases

haplotypes

gene

8 Citations (Scopus)

Association of HLA class I markers with multiple sclerosis in the Italian and UK population: Evidence of two independent protective effects

Bergamaschi, L., Ban, M., Barizzone, N., Leone, M., Ferrante, D., Fasano, M. E., Guerini, F. R., Corrado, L., Naldi, P., Dametto, E., Agliardi, C., Salvetti, M., Mechelli, R., Galimberti, D., Scarpini, E., Cavalla, P., Bargiggia, V., Caputo, D., Cordera, S., Monaco, F. & 2 others, Momigliano-Richiardi, P. & D'Alfonso, S., Jul 2011, In : Journal of Medical Genetics. 48, 7, p. 485-492 8 p.

Research output: Contribution to journal › Article

Multiple Sclerosis

HLA-A Antigens

Alleles

Haplotypes

Population

19 Citations (Scopus)

HLA polymorphisms in Italian children with autism spectrum disorders: Results of a family based linkage study

Guerini, F. R., Bolognesi, E., Chiappedi, M., De Silvestri, A., Ghezzo, A., Zanette, M., Rusconi, B., Manca, S., Sotgiu, S., Agliardi, C. & Clerici, M., Jan 2011, In : Journal of Neuroimmunology. 230, 1-2, p. 135-142 8 p.

Research output: Contribution to journal › Article

Alleles

Haplotypes

HLA-A Antigens

HLA-B Antigens

Single Nucleotide Polymorphism

16 Citations (Scopus)

Intrafamiliar transmission of Kaposi's sarcomaassociated herpesvirus and seronegative infection in family members of classic Kaposi's sarcoma patients

Mancuso, R., Brambilla, L., Agostini, S., Biffi, R., Hernis, A., Guerini, F. R., Agliardi, C., Tourlaki, A., Bellinvia, M. & Clerici, M., Apr 2011, In : Journal of General Virology. 92, 4, p. 744-751 8 p.

Research output: Contribution to journal › Article

Herpesviridae Infections

Human Herpesvirus 8

Kaposi's Sarcoma

Saliva

Viral DNA

29 Citations (Scopus)

SNAP-25 single nucleotide polymorphisms are associated with hyperactivity in autism spectrum disorders

Guerini, F. R., Bolognesi, E., Chiappedi, M., Manca, S., Ghezzo, A., Agliardi, C., Sotgiu, S., Usai, S., Matteoli, M. & Clerici, M., Sep 2011, In : Pharmacological Research. 64, 3, p. 283-288 6 p.

Research output: Contribution to journal › Article

Synaptosomal-Associated Protein 25

Single Nucleotide Polymorphism

Homeostasis

Calcium

Genes

48 Citations (Scopus)

Vitamin D receptor (VDR) gene SNPs influence VDR expression and modulate protection from multiple sclerosis in HLA-DRB1*15-positive individuals

Agliardi, C., Guerini, F. R., Saresella, M., Caputo, D., Leone, M. A., Zanzottera, M., Bolognesi, E., Marventano, I., Barizzone, N., Fasano, M. E., Al-Daghri, N. & Clerici, M., Oct 2011, In : Brain, Behavior, and Immunity. 25, 7, p. 1460-1467 8 p.

Research output: Contribution to journal › Article

HLA-DRB1 Chains

Calcitriol Receptors

Multiple Sclerosis

Single Nucleotide Polymorphism

Genes

2010

40 Citations (Scopus)

HLA-class i markers and multiple sclerosis susceptibility in the Italian population

Bergamaschi, L., Leone, M. A., Fasano, M. E., Guerini, F. R., Ferrante, D., Bolognesi, E., Barizzone, N., Corrado, L., Naldi, P., Agliardi, C., Dametto, E., Salvetti, M., Visconti, A., Galimberti, D., Scarpini, E., Vercellino, M., Bergamaschi, R., Monaco, F., Caputo, D., Momigliano-Richiardi, P. & 1 others, D'Alfonso, S., Mar 2010, In : Genes and Immunity. 11, 2, p. 173-180 8 p.

Research output: Contribution to journal › Article

varespladib methyl

Multiple Sclerosis

Population

Linkage Disequilibrium

Haplotypes

31 Citations (Scopus)

KIRs and their HLA ligands in Remitting-Relapsing Multiple Sclerosis

Fusco, C., Guerini, F. R., Nocera, G., Ventrella, G., Caputo, D., Valentino, M. A., Agliardi, C., Gallotti, J., Morra, V. B., Florio, C., Clerici, M. & Lombardi, M. L., Dec 15 2010, In : Journal of Neuroimmunology. 229, 1-2, p. 232-237 6 p.

Research output: Contribution to journal › Article

Relapsing-Remitting Multiple Sclerosis

KIR Receptors

Ligands

Multiple Sclerosis

HLA-A Antigens

2009

3 Citations (Scopus)

Association study of the HLA-A2 allele in Italian Alzheimer disease patients

Guerini, F. R., Calabrese, E., Agliardi, C., Zanzottera, M., Franceschi, M., Grimaldi, L. M. E., Nemni, R. & Ferrante, P., Dec 2009, In : Neurobiology of Aging. 30, 12, p. 2082-2083 2 p.

Research output: Contribution to journal › Article

HLA Antigens

varespladib methyl

Alzheimer Disease

Alleles

Age of Onset

58 Citations (Scopus)

BDNF Val66Met polymorphism is associated with cognitive impairment in Italian patients with Parkinson's disease

Guerini, F. R., Beghi, E., Riboldazzi, G., Zangaglia, R., Pianezzola, C., Bono, G., Casali, C., Di Lorenzo, C., Agliardi, C., Nappi, G., Clerici, M. & Martignoni, E., Nov 2009, In : European Journal of Neurology. 16, 11, p. 1240-1245 6 p.

Research output: Contribution to journal › Article

Brain-Derived Neurotrophic Factor

Parkinson Disease

Genotype

Cognitive Dysfunction

Homozygote

16 Citations (Scopus)

Family-based transmission analysis of HLA genetic markers in Sardinian children with autistic spectrum disorders

Guerini, F. R., Bolognesi, E., Manca, S., Sotgiu, S., Zanzottera, M., Agliardi, C., Usai, S. & Clerici, M., Mar 2009, In : Human Immunology. 70, 3, p. 184-190 7 p.

Research output: Contribution to journal › Article

Autistic Disorder

HLA Antigens

Genetic Markers

Single Nucleotide Polymorphism

Haplotypes

13 Citations (Scopus)

HLA-A*01 is associated with late onset of Alzheimer's disease in Italian patients

Guerini, F. R., Tinelli, C., Calabrese, E., Agliardi, C., Zanzottera, M., De Silvestri, A., Franceschi, M., Grimaldi, L. M. E., Nemni, R. & Clerici, M., Oct 2009, In : International Journal of Immunopathology and Pharmacology. 22, 4, p. 991-999 9 p.

Research output: Contribution to journal › Article

HLA-A Antigens

Alzheimer Disease

Age of Onset

Alleles

Odds Ratio

2008

19 Citations (Scopus)

Analysis of CCR5, CCR2, SDF1 and RANTES gene polymorphisms in subjects with HIV-related PML and not determined leukoencephalopathy

Guerini, F. R., Delbue, S., Zanzottera, M., Agliardi, C., Saresella, M., Mancuso, R., Maserati, R., Marchioni, E., Gori, A. & Ferrante, P., Jan 2008, In : Biomedicine and Pharmacotherapy. 62, 1, p. 26-30 5 p.

Research output: Contribution to journal › Article

Progressive Multifocal Leukoencephalopathy

Leukoencephalopathies

Chemokine CCL5

HIV

JC Virus