1986 …2019

Research output per year

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Research Output

2019

2B4 dysfunction in XLP1 NK cells: More than inability to control EBV infection

Pende, D., Meazza, R., Marcenaro, S., Aricò, M. & Bottino, C., Jul 2019, In : Clinical Immunology. 204, p. 31-36 6 p.

Research output: Contribution to journalReview article

A combined immunodeficiency with severe infections, inflammation, and allergy caused by ARPC1B deficiency

Volpi, S., Cicalese, M. P., Tuijnenburg, P., Tool, A. T. J., Cuadrado, E., Abu-Halaweh, M., Ahanchian, H., Alzyoud, R., Akdemir, Z. C., Barzaghi, F., Blank, A., Boisson, B., Bottino, C., Brigida, I., Caorsi, R., Casanova, J-L., Chiesa, S., Chinn, I. K., Dückers, G., Enders, A. & 32 others, Erichsen, H. C., Forbes, L. R., Gambin, T., Gattorno, M., Karimiani, E. G., Giliani, S., Gold, M. S., Jacobsen, E-M., Jansen, M. H., King, J. R., Laxer, R. M., Lupski, J. R., Mace, E., Marcenaro, S., Maroofian, R., Meijer, A. B., Niehues, T., Notarangelo, L. D., Orange, J., Pannicke, U., Pearson, C., Picco, P., Quinn, P. J., Schulz, A., Seeborg, F., Stray-Pedersen, A., Tawamie, H., van Leeuwen, E. M. M., Aiuti, A., Yeung, R., Schwarz, K. & Kuijpers, T. W., Jun 2019, In : Journal of Allergy and Clinical Immunology. 143, 6, p. 2296-2299 4 p.

Research output: Contribution to journalArticle

Cell-laden hydrogel as a clinical-relevant 3D model for analyzing neuroblastoma growth, immunophenotype, and susceptibility to therapies

Marrella, A., Dondero, A., Aiello, M., Casu, B., Olive, D., Regis, S., Bottino, C., Pende, D., Meazza, R., Caluori, G., Castriconi, R. & Scaglione, S., Jan 1 2019, In : Frontiers in Immunology. 10, AUG, Article 1876.

Research output: Contribution to journalArticle

Open Access

Cell-laden hydrogel as a clinical-relevant 3D model for analyzing neuroblastoma growth, immunophenotype, and susceptibility to therapies

Marrella, A., Dondero, A., Aiello, M., Casu, B., Olive, D., Regis, S., Bottino, C., Pende, D., Meazza, R., Caluori, G., Castriconi, R. & Scaglione, S., 2019, In : Frontiers in Immunology. 10, AUG

Research output: Contribution to journalArticle

Novel Immunoregulatory Functions of IL-18, an Accomplice of TGF-β1

Casu, B., Dondero, A., Regis, S., Caliendo, F., Petretto, A., Bartolucci, M., Bellora, F., Bottino, C. & Castriconi, R., Jan 11 2019, In : Cancers. 11, 1

Research output: Contribution to journalArticle

2018

2B4 dysfunction in XLP1 NK cells: More than inability to control EBV infection

Pende, D., Meazza, R., Marcenaro, S., Aricò, M. & Bottino, C., Jan 1 2018, (Accepted/In press) In : Clinical Immunology.

Research output: Contribution to journalArticle

Analysis of KIR3DP1 polymorphism provides relevant information on centromeric KIR gene content

Bono, M., Pende, D., Bertaina, A., Moretta, A., Chiesa, M. D., Sivori, S., Zecca, M., Locatelli, F., Moretta, L., Bottino, C. & Falco, M., Sep 1 2018, In : Journal of Immunology. 201, 5, p. 1460-1467 8 p.

Research output: Contribution to journalArticle

Analysis of KIR3DP1 Polymorphism Provides Relevant Information on Centromeric KIR Gene Content

Bono, M., Pende, D., Bertaina, A., Moretta, A., Della Chiesa, M., Sivori, S., Zecca, M., Locatelli, F., Moretta, L., Bottino, C. & Falco, M., Sep 1 2018, In : Journal of Immunology. 201, 5, p. 1460-1467 8 p.

Research output: Contribution to journalArticle

Molecular Mechanisms Directing Migration and Retention of Natural Killer Cells in Human Tissues

Castriconi, R., Carrega, P., Dondero, A., Bellora, F., Casu, B., Regis, S., Ferlazzo, G. & Bottino, C., 2018, In : Frontiers in Immunology. 9, p. 2324

Research output: Contribution to journalReview article

Nidogen-1 is a novel extracellular ligand for the NKp44 activating receptor

Gaggero, S., Bruschi, M., Petretto, A., Parodi, M., Zotto, G. D., Lavarello, C., Prato, C., Santucci, L., Barbuto, A., Bottino, C., Candiano, G., Moretta, A., Vitale, M., Moretta, L. & Cantoni, C., 2018, In : OncoImmunology. 7, 9, p. e1470730

Research output: Contribution to journalArticle

Nidogen-1 is a novel extracellular ligand for the NKp44 activating receptor

Gaggero, S., Bruschi, M., Petretto, A., Parodi, M., Del Zotto, G., Lavarello, C., Prato, C., Santucci, L., Barbuto, A., Bottino, C., Candiano, G., Moretta, A., Vitale, M., Moretta, L. & Cantoni, C., 2018, In : OncoImmunology. 7, 9, p. e1470730 19 p.

Research output: Contribution to journalArticle

Nidogen-1 is a novel extracellular ligand for the NKp44 activating receptor

Gaggero, S., Bruschi, M., Petretto, A., Parodi, M., Zotto, G. D., Lavarello, C., Prato, C., Santucci, L., Barbuto, A., Bottino, C., Candiano, G., Moretta, A., Vitale, M., Moretta, L. & Cantoni, C., 2018, In : OncoImmunology. 7, 9

Research output: Contribution to journalArticle

2017

Imatinib and nilotinib off-target effects on human NK cells, monocytes, and M2 macrophages

Bellora, F., Dondero, A., Corrias, M. V., Casu, B., Regis, S., Caliendo, F., Moretta, A., Cazzola, M., Elena, C., Vinti, L., Locatelli, F., Bottino, C. & Castriconi, R., Aug 15 2017, In : Journal of Immunology. 199, 4, p. 1516-1525 10 p.

Research output: Contribution to journalArticle

Imatinib and nilotinib off-target effects on human NK cells, monocytes, and M2 macrophages

Bellora, F., Dondero, A., Corrias, M. V., Casu, B., Regis, S., Caliendo, F., Moretta, A., Cazzola, M., Elena, C., Vinti, L., Locatelli, F., Bottino, C. & Castriconi, R., 2017, In : Journal of Immunology. 199, 4, p. 1516-1525 10 p.

Research output: Contribution to journalArticle

Imatinib and nilotinib off-target effects on human NK cells, monocytes, and M2 macrophages

Bellora, F., Dondero, A., Corrias, M. V., Casu, B., Regis, S., Caliendo, F., Moretta, A., Cazzola, M., Elena, C., Vinti, L., Locatelli, F., Bottino, C. & Castriconi, R., Aug 15 2017, In : Journal of Immunology. 199, 4, p. 1516-1525 10 p.

Research output: Contribution to journalArticle

Inhibitory 2B4 contributes to NK cell education and immunological derangements in XLP1 patients

Meazza, R., Falco, M., Marcenaro, S., Loiacono, F., Canevali, P., Bellora, F., Tuberosa, C., Locatelli, F., Micalizzi, C., Moretta, A., Mingari, M. C., Moretta, L., Aricò, M., Bottino, C. & Pende, D., Jun 2017, In : European Journal of Immunology. 47, 6, p. 1051-1061 11 p.

Research output: Contribution to journalArticle

Inhibitory 2B4 contributes to NK cell education and immunological derangements in XLP1 patients

Meazza, R., Falco, M., Marcenaro, S., Loiacono, F., Canevali, P., Bellora, F., Tuberosa, C., Locatelli, F., Micalizzi, C., Moretta, A., Mingari, M. C., Moretta, L., Aricò, M., Bottino, C. & Pende, D., Jun 2017, In : European Journal of Immunology. 47, 6, p. 1051-1061 11 p.

Research output: Contribution to journalArticle

Inhibitory 2B4 contributes to NK cell education and immunological derangements in XLP1 patients

Meazza, R., Falco, M., Marcenaro, S., Loiacono, F., Canevali, P., Bellora, F., Tuberosa, C., Locatelli, F., Micalizzi, C., Moretta, A., Mingari, M. C., Moretta, L., Aricò, M., Bottino, C. & Pende, D., Jun 1 2017, In : European Journal of Immunology. 47, 6, p. 1051-1061 11 p.

Research output: Contribution to journalArticle

NK cells and multiple myeloma-associated endothelial cells: molecular interactions and influence of IL-27

Dondero, A., Casu, B., Bellora, F., Vacca, A., De Luisi, A., Frassanito, M. A., Cantoni, C., Gaggero, S., Olive, D., Moretta, A., Bottino, C. & Castriconi, R., May 23 2017, In : Oncotarget. 8, 21, p. 35088-35102 15 p.

Research output: Contribution to journalArticle

TGF-ß1 downregulates the expression of CX3CR1 by inducing miR-27a-5p in primary human NK cells

Regis, S., Caliendo, F., Dondero, A., Casu, B., Romano, F., Loiacono, F., Moretta, A., Bottino, C. & Castriconi, R., Jul 25 2017, In : Frontiers in Immunology. 8, JUL, 868.

Research output: Contribution to journalArticle

TGF-β1 Downregulates the Expression of CX3CR1 by Inducing miR-27a-5p in Primary Human NK Cells

Regis, S., Caliendo, F., Dondero, A., Casu, B., Romano, F., Loiacono, F., Moretta, A., Bottino, C. & Castriconi, R., 2017, In : Frontiers in Immunology. 8, p. 868

Research output: Contribution to journalArticle

2016

CIS is a negative regulator of IL-15-mediated signals in NK cells

Bottino, C., Dondero, A., Moretta, A. & Castriconi, R., 2016, In : Translational Cancer Research. 5, p. S875-S877

Research output: Contribution to journalComment/debate

Hematopoietic stem cell transplantation: Improving alloreactive Bw4 donor selection by genotyping codon 86 of KIR3DL1/S1

Alicata, C., Pende, D., Meazza, R., Canevali, P., Loiacono, F., Bertaina, A., Locatelli, F., Nemat-Gorgani, N., Guethlein, L. A., Parham, P., Moretta, L., Moretta, A., Bottino, C., Norman, P. J. & Falco, M., Jun 1 2016, In : European Journal of Immunology. 46, 6, p. 1511-1517 7 p.

Research output: Contribution to journalArticle

Hematopoietic stem cell transplantation: Improving alloreactive Bw4 donor selection by genotyping codon 86 of KIR3DL1/S1

Alicata, C., Pende, D., Meazza, R., Canevali, P., Loiacono, F., Bertaina, A., Locatelli, F., Nemat-Gorgani, N., Guethlein, L. A., Parham, P., Moretta, L., Moretta, A., Bottino, C., Norman, P. J. & Falco, M., Jun 1 2016, In : European Journal of Immunology. 46, 6, p. 1511-1517 7 p.

Research output: Contribution to journalArticle

Hematopoietic stem cell transplantation: Improving alloreactive Bw4 donor selection by genotyping codon 86 of KIR3DL1/S1

Alicata, C., Pende, D., Meazza, R., Canevali, P., Loiacono, F., Bertaina, A., Locatelli, F., Nemat-Gorgani, N., Guethlein, L. A., Parham, P., Moretta, L., Moretta, A., Bottino, C., Norman, P. J. & Falco, M., Jun 1 2016, In : European Journal of Immunology. 46, 6, p. 1511-1517 7 p.

Research output: Contribution to journalArticle

Mesenchymal Stromal Cells Induce Peculiar Alternatively Activated Macrophages Capable of Dampening Both Innate and Adaptive Immune Responses

Chiossone, L., Conte, R., Spaggiari, G. M., Serra, M., Romei, C., Bellora, F., Becchetti, F., Andaloro, A., Moretta, L. & Bottino, C., 2016, In : Stem Cells. 34, 7, p. 1909-1921 13 p.

Research output: Contribution to journalArticle

Mesenchymal Stromal Cells Induce Peculiar Alternatively Activated Macrophages Capable of Dampening Both Innate and Adaptive Immune Responses

Chiossone, L., Conte, R., Spaggiari, G. M., Serra, M., Romei, C., Bellora, F., Becchetti, F., Andaloro, A., Moretta, L. & Bottino, C., Jul 1 2016, In : Stem Cells. 34, 7, p. 1909-1921 13 p.

Research output: Contribution to journalArticle

NK Cells, Tumor Cell Transition, and Tumor Progression in Solid Malignancies: New Hints for NK-Based Immunotherapy?

Cantoni, C., Huergo-Zapico, L., Parodi, M., Pedrazzi, M., Mingari, M. C., Moretta, A., Sparatore, B., Gonzalez, S., Olive, D., Bottino, C., Castriconi, R. & Vitale, M., 2016, In : Journal of Immunology Research. 2016, 4684268.

Research output: Contribution to journalReview article

NK Cells, Tumor Cell Transition, and Tumor Progression in Solid Malignancies: New Hints for NK-Based Immunotherapy?

Cantoni, C., Huergo-Zapico, L., Parodi, M., Pedrazzi, M., Mingari, M. C., Moretta, A., Sparatore, B., Gonzalez, S., Olive, D., Bottino, C., Castriconi, R. & Vitale, M., 2016, In : Journal of Immunology Research. 2016, 4684268.

Research output: Contribution to journalReview article

Oxysterol mixture and, in particular, 27-hydroxycholesterol drive M2 polarization of human macrophages

Marengo, B., Bellora, F., Ricciarelli, R., De Ciucis, C., Furfaro, A., Leardi, R., Colla, R., Pacini, D., Traverso, N., Moretta, A., Pronzato, M. A., Bottino, C. & Domenicotti, C., Jan 1 2016, In : BioFactors. 42, 1, p. 80-92 13 p.

Research output: Contribution to journalArticle

PD-L1 expression in metastatic neuroblastoma as an additional mechanism for limiting immune surveillance

Dondero, A., Pastorino, F., Chiesa, M. D., Corrias, M. V., Morandi, F., Pistoia, V., Olive, D., Bellora, F., Locatelli, F., Castellano, A., Moretta, L., Moretta, A., Bottino, C. & Castriconi, R., 2016, In : OncoImmunology. 5, 1

Research output: Contribution to journalArticle

PD-L1 expression in metastatic neuroblastoma as an additional mechanism for limiting immune surveillance

Dondero, A., Pastorino, F., Chiesa, M. D., Corrias, M. V., Morandi, F., Pistoia, V., Olive, D., Bellora, F., Locatelli, F., Castellano, A., Moretta, L., Moretta, A., Bottino, C. & Castriconi, R., 2016, In : OncoImmunology. 5, 1

Research output: Contribution to journalArticle

2014

Diagnosing XLP1 in patients with hemophagocytic lymphohistiocytosis

Meazza, R., Tuberosa, C., Cetica, V., Falco, M., Parolini, S., Grieve, S., Griffiths, G. M., Sieni, E., Marcenaro, S., Micalizzi, C., Montin, D., Fagioli, F., Moretta, A., Mingari, M. C., Moretta, L., Notarangelo, L. D., Bottino, C., Aricò, M. & Pende, D., Dec 1 2014, In : Journal of Allergy and Clinical Immunology. 134, 6, p. 1381-1387.e7

Research output: Contribution to journalArticle

Human NK cells and NK receptors

Bellora, F., Castriconi, R., Dondero, A., Carrega, P., Mantovani, A., Ferlazzo, G., Moretta, A. & Bottino, C., 2014, In : Immunology Letters. 161, 2, p. 168-173 6 p.

Research output: Contribution to journalArticle

In vivo generation of decidual natural killer cells from resident hematopoietic progenitors

Chiossone, L., Vacca, P., Orecchia, P., Croxatto, D., Damonte, P., Astigiano, S., Barbieri, O., Bottino, C., Moretta, L. & Mingari, M. C., Mar 1 2014, In : Haematologica. 99, 3, p. 448-457 10 p.

Research output: Contribution to journalArticle

Natural killer cells and neuroblastoma: Tumor recognition, escape mechanisms, and possible novel immunotherapeutic approaches

Bottino, C., Dondero, A., Bellora, F., Moretta, L., Locatelli, F., Pistoia, V., Moretta, A. & Castriconi, R., 2014, In : Frontiers in Immunology. 5, FEB, Article 56.

Research output: Contribution to journalArticle

TLR activation of tumor-associated macrophages from ovarian cancer patients triggers cytolytic activity of NK cells

Bellora, F., Castriconi, R., Dondero, A., Pessino, A., Nencioni, A., Liggieri, G., Moretta, L., Mantovani, A., Moretta, A. & Bottino, C., 2014, In : European Journal of Immunology. 44, 6, p. 1814-1822 9 p.

Research output: Contribution to journalArticle

XLP1 inhibitory effect by 2B4 does not affect DNAM-1 and NKG2D activating pathways in NK cells

Meazza, R., Tuberosa, C., Cetica, V., Falco, M., Loiacono, F., Parolini, S., Micalizzi, C., Moretta, A., Mingari, M. C., Moretta, L., Bottino, C., Aricò, M. & Pende, D., 2014, In : European Journal of Immunology. 44, 5, p. 1526-1534 9 p.

Research output: Contribution to journalArticle

2013

Cell surface expression of activating receptors and co-receptors on peripheral blood NK cells in mixed cryoglobulinemia

Puxeddu, I., Bongiorni, F., Chimenti, D., Capecchi, R., Bombardieri, S., Moretta, A., Bottino, C. & Migliorini, P., Jan 2013, In : Joint Bone Spine. 80, 1, p. 107-108 2 p.

Research output: Contribution to journalArticle

KIR and KIR ligand polymorphism: A new area for clinical applications?

Falco, M., Moretta, L., Moretta, A. & Bottino, C., Dec 2013, In : Tissue Antigens. 82, 6, p. 363-373 11 p.

Research output: Contribution to journalArticle

Neuroblastoma-derived IL-β1 modulates the chemokine receptor repertoire of human resting nk cells

Castriconi, R., Dondero, A., Bellora, F., Moretta, L., Castellano, A., Locatelli, F., Corrias, M. V., Moretta, A. & Bottino, C., May 15 2013, In : Journal of Immunology. 190, 10, p. 5321-5328 8 p.

Research output: Contribution to journalArticle

Transcriptional Profiling of Human Monocytes Identifies the Inhibitory Receptor CD300a as Regulator of Transendothelial Migration

Ghavampour, S., Lange, C., Bottino, C. & Gerke, V., Sep 18 2013, In : PLoS One. 8, 9, e73981.

Research output: Contribution to journalArticle

2012

Cell surface expression of activating receptors and co-receptors on peripheral blood NK cells in systemic autoimmune diseases

Puxeddu, I., Bongiorni, F., Chimenti, D., Bombardieri, S., Moretta, A., Bottino, C. & Migliorini, P., 2012, In : Scandinavian Journal of Rheumatology. 41, 4, p. 298-304 7 p.

Research output: Contribution to journalArticle

2011

Alternatively spliced NKp30 isoforms affect the prognosis of gastrointestinal stromal tumors

Delahaye, N. F., Rusakiewicz, S., Martins, I., Ménard, C., Roux, S., Lyonnet, L., Paul, P., Sarabi, M., Chaput, N., Semeraro, M., Minard-Colin, V., Poirier-Colame, V., Chaba, K., Flament, C., Baud, V., Authier, H., Kerdine-Römer, S., Pallardy, M., Cremer, I., Peaudecerf, L. & 21 others, Rocha, B., Valteau-Couanet, D., Gutierrez, J. C., Nunès, J. A., Commo, F., Bonvalot, S., Ibrahim, N., Terrier, P., Opolon, P., Bottino, C., Moretta, A., Tavernier, J., Rihet, P., Coindre, J. M., Blay, J. Y., Isambert, N., Emile, J. F., Vivier, E., Lecesne, A., Kroemer, G. & Zitvogel, L., Jun 2011, In : Nature Medicine. 17, 6, p. 700-707 8 p.

Research output: Contribution to journalArticle