19962020

Research output per year

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Research Output

2020

Lamin A involvement in ageing processes

Cenni, V., Capanni, C., Mattioli, E., Schena, E., Squarzoni, S., Bacalini, M. G., Garagnani, P., Salvioli, S., Franceschi, C. & Lattanzi, G., May 21 2020, In : Ageing Research Reviews. p. 101073

Research output: Contribution to journalReview article

2019

Altered adipocyte differentiation and unbalanced autophagy in type 2 Familial Partial Lipodystrophy: an in vitro and in vivo study of adipose tissue browning

Pellegrini, C., Columbaro, M., Schena, E., Prencipe, S., Andrenacci, D., Iozzo, P., Angela Guzzardi, M., Capanni, C., Mattioli, E., Loi, M., Araujo-Vilar, D., Squarzoni, S., Cinti, S., Morselli, P., Giorgetti, A., Zanotti, L., Gambineri, A. & Lattanzi, G., Aug 2 2019, In : Experimental and Molecular Medicine. 51, 8, p. 1-17 17 p.

Research output: Contribution to journalArticle

Long term breeding of the Lmna G609G progeric mouse: Characterization of homozygous and heterozygous models

Zaghini, A., Sarli, G., Barboni, C., Sanapo, M., Pellegrino, V., Diana, A., Linta, N., Rambaldi, J., D'Apice, M. R., Murdocca, M., Baleani, M., Baruffaldi, F., Fognani, R., Mecca, R., Festa, A., Papparella, S., Paciello, O., Prisco, F., Capanni, C., Loi, M. & 3 others, Schena, E., Lattanzi, G. & Squarzoni, S., Nov 30 2019, In : Experimental Gerontology. 130, p. 1-18 18 p.

Research output: Contribution to journalArticle

Statins and Histone Deacetylase Inhibitors Affect Lamin A/C - Histone Deacetylase 2 Interaction in Human Cells

Mattioli, E., Andrenacci, D., Mai, A., Valente, S., Robijns, J., De Vos, W. H., Capanni, C. & Lattanzi, G., Jan 31 2019, In : Frontiers in Cell and Developmental Biology. 7, p. 1-10 10 p.

Research output: Contribution to journalArticle

2017
2016

Barrier-to-autointegration factor (BAF) involvement in prelamin a-related chromatin organization changes

Loi, M., Cenni, V., Duchi, S., Squarzoni, S., Lopez-Otin, C., Foisner, R., Lattanzi, G. & Capanni, C., Mar 29 2016, In : Oncotarget. 7, 13, p. 15662-15677 16 p.

Research output: Contribution to journalArticle

2015

All-trans retinoic acid and rapamycin normalize Hutchinson Gilford progeria fibroblast phenotype

Pellegrini, C., Columbaro, M., Capanni, C., D'Apice, M. R., Cavallo, C., Murdocca, M., Lattanzi, G. & Squarzoni, S., 2015, In : Oncotarget. 6, 30, p. 29914-29928 15 p.

Research output: Contribution to journalArticle

Inhibition of metalloproteinase activity in FANCA Is linked to altered oxygen metabolism

Ravera, S., Capanni, C., Tognotti, D., Bottega, R., Columbaro, M., Dufour, C., Cappelli, E. & Degan, P., Mar 1 2015, In : Journal of Cellular Physiology. 230, 3, p. 603-609 7 p.

Research output: Contribution to journalArticle

Slug transcription factor and nuclear Lamin B1 are upregulated in osteoarthritic chondrocytes

Piva, R., Lambertini, E., Manferdini, C., Capanni, C., Penolazzi, L., Gabusi, E., Paolella, F., Lolli, A., Angelozzi, M., Lattanzi, G. & Lisignoli, G., Jul 1 2015, In : Osteoarthritis and Cartilage. 23, 7, p. 1226-1230 5 p.

Research output: Contribution to journalArticle

2014

Diverse lamin-dependent mechanisms interact to control chromatin dynamics. Focus on laminopathies

Camozzi, D., Capanni, C., Cenni, V., Mattioli, E., Columbaro, M., Squarzoni, S. & Lattanzi, G., Sep 1 2014, In : Nucleus (Austin, Tex.). 5, 5, p. 427-440 14 p.

Research output: Contribution to journalArticle

Lamins are rapamycin targets that impact human longevity: A study in centenarians

Lattanzi, G., Ortolani, M., Columbaro, M., Prencipe, S., Mattioli, E., Lanzarini, C., Maraldi, N. M., Cenni, V., Garagnani, P., Salvioli, S., Storci, G., Bonafè, M., Capanni, C. & Franceschi, C., Jan 1 2014, In : Journal of Cell Science. 127, 1, p. 147-157 11 p.

Research output: Contribution to journalArticle

Rapamycin treatment of Mandibuloacral Dysplasia cells rescues localization of chromatin-associated proteins and cell cycle dynamics

Cenni, V., Capanni, C., Mattioli, E., Columbaro, M., Wehnert, M., Ortolani, M., Fini, M., Novelli, G., Bertacchini, J., Maraldi, N. M., Marmiroli, S., D'Apice, M. R., Prencipe, S., Squarzoni, S. & Lattanzi, G., 2014, In : Aging. 6, 9, p. 755-770 16 p.

Research output: Contribution to journalArticle

Treatment of FANCA cells with resveratrol and N-acetylcysteine: a comparative study

Columbaro, M., Ravera, S., Capanni, C., Panfoli, I., Cuccarolo, P., Stroppiana, G., Degan, P. & Cappelli, E., 2014, In : PLoS One. 9, 7, p. e104857

Research output: Contribution to journalArticle

2013

Changes in vimentin, lamin A/C and mitofilin induce aberrant cell organization in fibroblasts from Fanconi anemia complementation group A (FA-A) patients

Capanni, C., Bruschi, M., Columbaro, M., Cuccarolo, P., Ravera, S., Dufour, C., Candiano, G., Petretto, A., Degan, P. & Cappelli, E., Oct 2013, In : Biochimie. 95, 10, p. 1838-1847 10 p.

Research output: Contribution to journalArticle

Mitochondrial respiratory chain Complex i defects in Fanconi anemia complementation group A

Ravera, S., Vaccaro, D., Cuccarolo, P., Columbaro, M., Capanni, C., Bartolucci, M., Panfoli, I., Morelli, A., Dufour, C., Cappelli, E. & Degan, P., Oct 2013, In : Biochimie. 95, 10, p. 1828-1837 10 p.

Research output: Contribution to journalArticle

2012

Altered chromatin organization and SUN2 localization in mandibuloacral dysplasia are rescued by drug treatment

Camozzi, D., D'Apice, M. R., Schena, E., Cenni, V., Columbaro, M., Capanni, C., Maraldi, N. M., Squarzoni, S., Ortolani, M., Novelli, G. & Lattanzi, G., Oct 2012, In : Histochemistry and Cell Biology. 138, 4, p. 643-651 9 p.

Research output: Contribution to journalArticle

Familial partial lipodystrophy, mandibuloacral dysplasia and restrictive dermopathy feature barrier-to-autointegration factor (BAF) nuclear redistribution

Capanni, C., Squarzoni, S., Cenni, V., D'Apice, M. R., Gambineri, A., Novelli, G., Wehnert, M., Pasquali, R., Maraldi, N. M. & Lattanzi, G., Oct 1 2012, In : Cell Cycle. 11, 19, p. 3568-3577 10 p.

Research output: Contribution to journalArticle

The empowerment of translational research: Lessons from laminopathies

Benedetti, S., Bernasconi, P., Bertini, E., Biagini, E., Boriani, G., Capanni, C., Carboni, N., Cenacchi, G., Columbaro, M., D'Adamo, M., Damico, A., Dapice, M. R., Fontana, M., Gambineri, A., Lattanzi, G., Liguori, R., Maraldi, N. M., Mazzanti, L., Mercuri, E., Mongini, T. & 21 others, Morandi, L. O., Neri, I., Nigro, G., Novelli, G., Ortolani, M., Pasquali, R., Pini, A., Petrini, S., Politano, L., Previtali, S., Pucci, L., Rapezzi, C., Ricci, G., Rodolico, C., Sbraccia, P., Scarano, E., Siciliano, G., Squarzoni, S., Toscano, A., Vercelli, L. & Ziacchi, M., 2012, In : Orphanet Journal of Rare Diseases. 7, 1, 37.

Research output: Contribution to journalArticle

2011

Autophagic degradation of farnesylated prelamin A as a therapeutic approach to lamin-linked progeria

Cenni, V., Capanni, C., Columbaro, M., Ortolani, M., D'Apice, M. R., Novelli, G., Fini, M., Marmiroli, S., Scarano, E., Maraldi, N. M., Squarzoni, S., Prencipe, S. & Lattanzi, G., 2011, In : European journal of histochemistry : EJH. 55, 4, p. 200-205 6 p.

Research output: Contribution to journalArticle

Laminopathies and lamin-associated signaling pathways

Maraldi, N. M., Capanni, C., Cenni, V., Fini, M. & Lattanzi, G., Apr 2011, In : Journal of Cellular Biochemistry. 112, 4, p. 979-992 14 p.

Research output: Contribution to journalArticle

Muscular laminopathies: Role of prelamin A in early steps of muscle differentiation

Maraldi, N. M., Capanni, C., Del Coco, R., Squarzoni, S., Columbaro, M., Mattioli, E., Lattanzi, G. & Manzoli, F. A., 2011, In : Advances in Enzyme Regulation. 51, 1, p. 246-256 11 p.

Research output: Contribution to journalArticle

Osteoblasts from a mandibuloacral dysplasia patient induce human blood precursors to differentiate into active osteoclasts

Avnet, S., Pallotta, R., Perut, F., Baldini, N., Pittis, M. G., Saponari, A., Lucarelli, E., Dozza, B., Greggi, T., Maraldi, N. M., Capanni, C., Mattioli, E., Columbaro, M. & Lattanzi, G., Jul 2011, In : Biochimica et Biophysica Acta - Molecular Basis of Disease. 1812, 7, p. 711-718 8 p.

Research output: Contribution to journalArticle

Prelamin A-mediated recruitment of SUN1 to the nuclear envelope directs nuclear positioning in human muscle

Mattioli, E., Columbaro, M., Capanni, C., Maraldi, N. M., Cenni, V., Scotlandi, K., Marino, M. T., Merlini, L., Squarzoni, S. & Lattanzi, G., Aug 2011, In : Cell Death and Differentiation. 18, 8, p. 1305-1315 11 p.

Research output: Contribution to journalArticle

2010

Lamin A precursor induces barrier-to-autointegration factor nuclear localization

Capanni, C., Cenni, V., Haraguchi, T., Squarzoni, S., Schüchner, S., Ogris, E., Novelli, G., Maraldi, N. M. & Lattanzi, G., Jul 1 2010, In : Cell Cycle. 9, 13, p. 2600-2610 11 p.

Research output: Contribution to journalArticle

Leupeptin preserves cardiac nitric oxide synthase 3 during reperfusion following long-term cardioplegia

Muscari, C., Capanni, C., Giordano, E., Stefanelli, C., Bonavita, F., Stanic, I., Bonaf, F., Caldarera, C. M. & Guarnieri, C., Nov 2010, In : Journal of Surgical Research. 164, 1

Research output: Contribution to journalArticle

Prelamin A processing and functional effects in restrictive dermopathy

Columbaro, M., Mattioli, E., Schena, E., Capanni, C., Cenni, V., Levy, N., Navarro, C. L., Del Coco, R., Squarzoni, S., Camozzi, D., Hutchison, C. J., Wehnert, M. & Lattanzi, G., Dec 1 2010, In : Cell Cycle. 9, 23, p. 4766-4768 3 p.

Research output: Contribution to journalArticle

2009

Different prelamin A forms accumulate in human fibroblasts: A study in experimental models and progeria

Dominici, S., Fiori, V., Magnani, M., Schena, E., Capanni, C., Camozzi, D., D'Apice, M. R., Le Dour, C., Auclair, M., Caron, M., Novelli, G., Vigouroux, C., Maraldi, N. M. & Lattanzi, G., Jan 2009, In : European journal of histochemistry : EJH. 53, 1, p. 43-52 10 p.

Research output: Contribution to journalArticle

Emerin-prelamin A interplay in human fibroblasts

Capanni, C., Del Coco, R., Mattioli, E., Camozzi, D., Columbaro, M., Schena, E., Merlini, L., Squarzoni, S., Maraldi, N. M. & Lattanzi, G., 2009, In : Biology of the cell / under the auspices of the European Cell Biology Organization. 101, 9, p. 541-554 14 p.

Research output: Contribution to journalArticle

2008

Apoptotic genes as potential markers of metastatic phenotype in human osteosarcoma cell lines

Zucchini, C., Rocchi, A., Manara, M. C., De Sanctis, P., Capanni, C., Bianchini, M., Carinci, P., Scotlandi, K. & Valvassori, L., Jan 2008, In : International Journal of Oncology. 32, 1, p. 17-31 15 p.

Research output: Contribution to journalArticle

Drugs affecting prelamin A processing: Effects on heterochromatin organization

Mattioli, E., Columbaro, M., Capanni, C., Santi, S., Maraldi, N. M., D'Apice, M. R., Novelli, G., Riccio, M., Squarzoni, S., Foisner, R. & Lattanzi, G., Feb 1 2008, In : Experimental Cell Research. 314, 3, p. 453-462 10 p.

Research output: Contribution to journalArticle

Prelamin A is involved in early steps of muscle differentiation

Capanni, C., Del Coco, R., Squarzoni, S., Columbaro, M., Mattioli, E., Camozzi, D., Rocchi, A., Scotlandi, K., Maraldi, N., Foisner, R. & Lattanzi, G., Dec 10 2008, In : Experimental Cell Research. 314, 20, p. 3628-3637 10 p.

Research output: Contribution to journalArticle

Remodelling of the nuclear lamina during human cytomegalovirus infection: Role of the viral proteins pUL50 and pUL53

Camozzi, D., Pignatelli, S., Valvo, C., Lattanzi, G., Capanni, C., Dal Monte, P. & Landini, M. P., Mar 2008, In : Journal of General Virology. 89, 3, p. 731-740 10 p.

Research output: Contribution to journalArticle

SREBP1 interaction with prelamin A forms: A pathogenic mechanism for lipodystrophic laminopathies

Maraldi, N. M., Capanni, C., Lattanzi, G., Camozzi, D., Facchini, A. & Manzoli, F. A., 2008, In : Advances in Enzyme Regulation. 48, 1, p. 209-223 15 p.

Research output: Contribution to journalArticle

2007

A pathogenic mechanism leading to partial lipodistrophy and prospects for pharmacological treatment of insulin resistance syndrome

Maraldi, N. M., Capanni, C., Mattioli, E., Columbaro, M., Squarzoni, S., Parnaik, W. K., Wehnert, M. & Lattanzi, G., Apr 2007, In : Acta Biomedica. 78, SUPPL. 1, p. 207-215 9 p.

Research output: Contribution to journalArticle

Prelamin A processing and heterochromatin dynamics in laminopathies

Maraldi, N. M., Mattioli, E., Lattanzi, G., Columbaro, M., Capanni, C., Camozzi, D., Squarzoni, S. & Manzoli, F. A., 2007, In : Advances in Enzyme Regulation. 47, p. 154-167 14 p.

Research output: Contribution to journalArticle

Pre-lamin A processing is linked to heterochromatin organization

Lattanzi, G., Columbaro, M., Mattioli, E., Cenni, V., Camozzi, D., Wehnert, M., Santi, S., Riccio, M., Del Coco, R., Maraldi, N. M., Squarzoni, S., Foisner, R. & Capanni, C., Dec 1 2007, In : Journal of Cellular Biochemistry. 102, 5, p. 1149-1159 11 p.

Research output: Contribution to journalArticle

2006

Laminopathies: A chromatin affair

Maraldi, N. M., Lattanzi, G., Capanni, C., Columbaro, M., Mattioli, E., Sabatelli, P., Squarzoni, S. & Manzoli, F. A., 2006, In : Advances in Enzyme Regulation. 46, 1, p. 33-49 17 p.

Research output: Contribution to journalArticle

Nuclear envelope proteins and chromatin arrangement: A pathogenic mechanism for laminopathies

Maraldi, N. M., Lattanzi, G., Capanni, C., Columbaro, M., Merlini, L., Mattioli, E., Sabatelli, P., Squarzoni, S. & Manzoli, F. A., Jan 2006, In : European journal of histochemistry : EJH. 50, 1, p. 1-8 8 p.

Research output: Contribution to journalArticle

Ultrastructural defects of collagen VI filaments in an Ullrich syndrome patient with loss of the α3(VI) N10-N7 domains

Squarzoni, S., Sabatelli, P., Bergamin, N., Guicheney, P., Demir, E., Merlini, L., Lattanzi, G., Ognibene, A., Capanni, C., Mattioli, E., Columbaro, M., Bonaldo, P. & Maraldi, N. M., Jan 2006, In : Journal of Cellular Physiology. 206, 1, p. 160-166 7 p.

Research output: Contribution to journalArticle

2005

Alterations of nuclear envelope and chromatin organization in mandibuloacral dysplasia, a rare form of laminopathy

Filesi, I., Gullotta, F., Lattanzi, G., D'Apice, M. R., Capanni, C., Nardone, A. M., Columbaro, M., Scarano, G., Mattioli, E., Sabatelli, P., Maraldi, N. M., Biocca, S. & Novelli, G., Oct 17 2005, In : Physiol Genomics. 23, 2, p. 150-158 9 p.

Research output: Contribution to journalArticle

Altered pre-lamin A processing is a common mechanism leading to lipodystrophy

Capanni, C., Mattioli, E., Columbaro, M., Lucarelli, E., Parnaik, V. K., Novelli, G., Wehnert, M., Cenni, V., Maraldi, N. M., Squarzoni, S. & Lattanzi, G., Jun 1 2005, In : Human Molecular Genetics. 14, 11, p. 1489-1502 14 p.

Research output: Contribution to journalArticle

Emerin increase in regenerating muscle fibers.

Squarzoni, S., Sabatelli, P., Capanni, C., Lattanzi, G., Rutigliano, C., Columbaro, M., Mattioli, E., Rocca, M. & Maraldi, N. M., Oct 2005, In : European journal of histochemistry : EJH. 49, 4, p. 355-362 8 p.

Research output: Contribution to journalArticle

Implications for nuclear organization and gene transcription of lamin A/C specific mutations

Maraldi, N. M., Lattanzi, G., Squarzoni, S., Capanni, C., Cenni, V. & Manzoli, F. A., 2005, In : Advances in Enzyme Regulation. 45, p. 1-16 16 p.

Research output: Contribution to journalArticle

Lamin A N-terminal phosphorylation is associated with myoblast activation: Impairment in Emery-Dreifuss muscular dystrophy

Cenni, V., Sabatelli, P., Mattioli, E., Marmiroli, S., Capanni, C., Ognibene, A., Squarzoni, S., Maraldi, N. M., Bonne, G., Columbaro, M., Merlini, L. & Lattanzi, G., Mar 2005, In : Journal of Medical Genetics. 42, 3, p. 214-220 7 p.

Research output: Contribution to journalArticle

Laminopathies: Involvement of structural nuclear proteins in the pathogenesis of an increasing number of human diseases

Maraldi, N. M., Squarzoni, S., Sabatelli, P., Capanni, C., Mattioli, E., Ognibene, A. & Lattanzi, G., May 2005, In : Journal of Cellular Physiology. 203, 2, p. 319-327 9 p.

Research output: Contribution to journalArticle

Rescue of heterochromatin organization in Hutchinson-Gilford progeria by drug treatment

Columbaro, M., Capanni, C., Mattioli, E., Novelli, G., Parnaik, V. K., Squarzoni, S., Maraldi, N. M. & Lattanzi, G., Nov 2005, In : Cellular and Molecular Life Sciences. 62, 22, p. 2669-2678 10 p.

Research output: Contribution to journalArticle

2003

Association of emerin with nuclear and cytoplasmic actin is regulated in differentiating myoblasts

Lattanzi, G., Cenni, V., Marmiroli, S., Capanni, C., Mattioli, E., Merlini, L., Squarzoni, S. & Maraldi, N. M., Apr 11 2003, In : Biochemical and Biophysical Research Communications. 303, 3, p. 764-770 7 p.

Research output: Contribution to journalArticle

Dysferlin in a hyperCKaemic patient with caveolin 3 mutation and in C2C12 cells after p38 MAP kinase inhibition

Capanni, C., Sabatelli, P., Mattioli, E., Ognibene, A., Columbaro, M., Lattanzi, G., Merlini, L., Minetti, C., Maraldi, N. M. & Squarzoni, S., Dec 31 2003, In : Experimental and Molecular Medicine. 35, 6, p. 538-544 7 p.

Research output: Contribution to journalArticle