20002019

Research output per year

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2019
2018

A Numb-Mdm2 fuzzy complex reveals an isoformspecific involvement of Numb in breast cancer

Colaluca, I. N., Basile, A., Freiburger, L., D'Uva, V., Disalvatore, D., Vecchi, M., Confalonieri, S., Tosoni, D., Cecatiello, V., Malabarba, M. G., Yang, C. J., Kainosho, M., Sattler, M., Mapelli, M., Pece, S. & di Fiore, P. P., Feb 1 2018, In : Journal of Cell Biology. 217, 2, p. 745-762 18 p.

Research output: Contribution to journalArticle

2017

Pre-clinical validation of a selective anti-cancer stem cell therapy for Numb-deficient human breast cancers

Tosoni, D., Pambianco, S., Ekalle Soppo, B., Zecchini, S., Bertalot, G., Pruneri, G., Viale, G., Di Fiore, P. P. & Pece, S., May 1 2017, In : EMBO Molecular Medicine. 9, 5, p. 655-671 17 p.

Research output: Contribution to journalArticle

The scaffold protein p140Cap limits ERBB2-mediated breast cancer progression interfering with Rac GTPase-controlled circuitries

Grasso, S., Chapelle, J., Salemme, V., Aramu, S., Russo, I., Vitale, N., Verdun di Cantogno, L., Dallaglio, K., Castellano, I., Amici, A., Centonze, G., Sharma, N., Lunardi, S., Cabodi, S., Cavallo, F., Lamolinara, A., Stramucci, L., Moiso, E., Provero, P., Albini, A. & 11 others, Sapino, A., Staaf, J., Di Fiore, P. P., Bertalot, G., Pece, S., Tosoni, D., Confalonieri, S., Iezzi, M., Di Stefano, P., Turco, E. & Defilippi, P., Mar 16 2017, In : Nature Communications. 8, p. 14797

Research output: Contribution to journalArticle

The scaffold protein p140Cap limits ERBB2-mediated breast cancer progression interfering with Rac GTPase-controlled circuitries

Grasso, S., Chapelle, J., Salemme, V., Aramu, S., Russo, I., Vitale, N., Di Cantogno, L. V., Dallaglio, K., Castellano, I., Amici, A., Centonze, G., Sharma, N., Lunardi, S., Cabodi, S., Cavallo, F., Lamolinara, A., Stramucci, L., Moiso, E., Provero, P., Albini, A. & 11 others, Sapino, A., Staaf, J., Di Fiore, P. P., Bertalot, G., Pece, S., Tosoni, D., Confalonieri, S., Iezzi, M., Di Stefano, P., Turco, E. & Defilippi, P., Mar 16 2017, In : Nature Communications. 8, 14797.

Research output: Contribution to journalArticle

2015

p63 sustains self-renewal of mammary cancer stem cells through regulation of Sonic Hedgehog signaling

Memmi, E. M., Sanarico, A. G., Giacobbe, A., Peschiaroli, A., Frezza, V., Cicalese, A., Pisati, F., Tosoni, D., Zhou, H., Tonon, G., Antonov, A., Melino, G., Pelicci, P. G. & Bernassola, F., Mar 17 2015, In : Proceedings of the National Academy of Sciences of the United States of America. 112, 11, p. 3499-3504 6 p.

Research output: Contribution to journalArticle

The Numb/p53 circuitry couples replicative self-renewal and tumor suppression in mammary epithelial cells

Tosoni, D., Zecchini, S., Coazzoli, M., Colaluca, I., Mazzarol, G., Rubio, A., Caccia, M., Villa, E., Zilian, O., Di Fiore, P. P. & Pece, S., Nov 23 2015, In : Journal of Cell Biology. 211, 4, p. 845-862 18 p.

Research output: Contribution to journalArticle

2012

Reciprocal repression between P53 and TCTP

Amson, R., Pece, S., Lespagnol, A., Vyas, R., Mazzarol, G., Tosoni, D., Colaluca, I., Viale, G., Rodrigues-Ferreira, S., Wynendaele, J., Chaloin, O., Hoebeke, J., Marine, J. C., Di Fiore, P. P. & Telerman, A., Jan 2012, In : Nature Medicine. 18, 1, p. 91-99 9 p.

Research output: Contribution to journalArticle

2010
2009

Alterations of the Notch pathway in lung cancer

Westhoff, B., Colaluca, I. N., D'Ario, G., Donzelli, M., Tosoni, D., Volorio, S., Pelosi, G., Spaggiari, L., Mazzarol, G., Viale, G., Pece, S. & Di Fiore, P. P., Dec 19 2009, In : Proceedings of the National Academy of Sciences of the United States of America. 106, 52, p. 22293-22298 6 p.

Research output: Contribution to journalArticle

CAP (Cbl associated protein) regulates receptor-mediated endocytosis

Tosoni, D. & Cestra, G., Jan 22 2009, In : FEBS Letters. 583, 2, p. 293-300 8 p.

Research output: Contribution to journalArticle

2008

Binding of sFRP-3 to EGF in the extra-cellular space affects proliferation, differentiation and morphogenetic events regulated by the two molecules

Scardigli, R., Gargioli, C., Tosoni, D., Borello, U., Sampaolesi, M., Sciorati, C., Cannata, S., Clementi, E., Brunelli, S. & Cossu, G., Jun 18 2008, In : PLoS One. 3, 6, e2471.

Research output: Contribution to journalArticle

Clathrin-Mediated Internalization Is Essential for Sustained EGFR Signaling but Dispensable for Degradation

Sigismund, S., Argenzio, E., Tosoni, D., Cavallaro, E., Polo, S. & Di Fiore, P. P., Aug 12 2008, In : Developmental Cell. 15, 2, p. 209-219 11 p.

Research output: Contribution to journalArticle

NUMB controls p53 tumour suppressor activity

Colaluca, I. N., Tosoni, D., Nuciforo, P., Senic-Matuglia, F., Galimberti, V., Viale, G., Pece, S. & Di Fiore, P. P., Jan 3 2008, In : Nature. 451, 7174, p. 76-80 5 p.

Research output: Contribution to journalArticle

2005

Relationships between EGFR signaling-competent and endocytosis-competent membrane microdomains

Puri, C., Tosoni, D., Comai, R., Rabellino, A., Segat, D., Caneva, F., Luzzi, P., Di Fiore, P. P. & Tacchetti, C., 2005, In : Molecular Biology of the Cell. 16, 6, p. 2704-2718 15 p.

Research output: Contribution to journalArticle

TTP specifically regulates the internalization of the transferrin receptor

Tosoni, D., Puri, C., Confalonieri, S., Salcini, A. E., De Camilli, P., Tacchetti, C. & Di Fiore, P. P., Dec 2 2005, In : Cell. 123, 5, p. 875-888 14 p.

Research output: Contribution to journalArticle

2004

A JC Virus-Induced Signal Is Required for Infection of Glial Cells by a Clathrin- and eps15-Dependent Pathway

Querbes, W., Benmerah, A., Tosoni, D., Di Fiore, P. P. & Atwood, W. J., Jan 2004, In : Journal of Virology. 78, 1, p. 250-256 7 p.

Research output: Contribution to journalArticle

2000

Determination, diversification and multipotency of mammalian myogenic cells

Cossu, G., De Angelis, L., Borello, U., Berarducci, B., Buffa, V., Sonnino, C., Coletta, M., Vivarelli, E., Bouche', M., Lattanzi, L., Tosoni, D., Di Donna, S., Berghella, L., Salvatori, G., Murphy, P., Cusella-De Angelis, M. G. & Molinaro, M., 2000, In : International Journal of Developmental Biology. 44, 6, p. 699-706 8 p.

Research output: Contribution to journalArticle