If you made any changes in Pure these will be visible here soon.

Research Output 1998 2019

Filter
Article
2019

Chitosan-based Scaffold Counteracts Hypertrophic and Fibrotic Markers in Chondrogenic Differentiated Mesenchymal Stromal Cells

Manferdini, C., Gabusi, E., Sartore, L., Dey, K., Agnelli, S., Almici, C., Bianchetti, A., Zini, N., Russo, D., Re, F., Mariani, E. & Lisignoli, G., Oct 2019, In : Journal of Tissue Engineering and Regenerative Medicine. 13, 10, p. 1896-1911 16 p.

Research output: Contribution to journalArticle

Collagen Type X
Chitosan
Mesenchymal Stromal Cells
Collagen
Scaffolds

Investigating the Role of Sustained Calcium Release in Silk-Gelatin-Based Three-Dimensional Bioprinted Constructs for Enhancing the Osteogenic Differentiation of Human Bone Marrow Derived Mesenchymal Stromal Cells

Sharma, A., Desando, G., Petretta, M., Chawla, S., Bartolotti, I., Manferdini, C., Paolella, F., Gabusi, E., Trucco, D., Ghosh, S. & Lisignoli, G., Feb 12 2019, In : ACS Biomaterials Science and Engineering. 5, 3, p. 1518-1533 16 p.

Research output: Contribution to journalArticle

Silk
Gelatin
Calcium
Bone
Fibroins

Osteoarthritic Milieu Affects Adipose-Derived Mesenchymal Stromal Cells

Manferdini, C., Paolella, F., Gabusi, E., Cattini, L., Rojewski, M., Schrezenmeier, H., Addimanda, O., Meliconi, R. & Lisignoli, G., Aug 19 2019, In : Journal of Orthopaedic Research. p. 1-12 12 p.

Research output: Contribution to journalArticle

Mesenchymal Stromal Cells
Synovial Fluid
Conditioned Culture Medium
CCR1 Receptors
Cell Movement

Rational Design and Development of Anisotropic and Mechanically Strong Gelatin-Based Stress Relaxing Hydrogels for Osteogenic/Chondrogenic Differentiation

Dey, K., Agnelli, S., Re, F., Russo, D., Lisignoli, G., Manferdini, C., Bernardi, S., Gabusi, E. & Sartore, L., Jul 12 2019, In : Macromolecular Bioscience. 19, 8, p. 1-18 18 p.

Research output: Contribution to journalArticle

Hydrogels
Gelatin
Mesenchymal Stromal Cells
Crosslinking
Polymers
Hyaluronic Acid
Amides
Genes
Modulation
Derivatives
2018
Osteochondritis Dissecans
Cartilage
Biomarkers
Scaffolds
Knee

Clinical and Biological Signature of Osteochondritis Dissecans in a Cross-Sectional Study

Gabusi, E., Manferdini, C., Paolella, F., Gambari, L., Kon, E., Filardo, G., Mariani, E. & Lisignoli, G., May 2018, In : BioMed Research International. 2018, p. 1-9 9 p.

Research output: Contribution to journalArticle

Osteochondritis Dissecans
Bone
Cartilage
Cross-Sectional Studies
Biomarkers

Effect of microfragmented adipose tissue on osteoarthritic synovial macrophage factors

Paolella, F., Manferdini, C., Gabusi, E., Gambari, L., Filardo, G., Kon, E., Mariani, E. & Lisignoli, G., Sep 6 2018, In : Journal of Cellular Physiology. 234, 4, p. 5044-5055 12 p.

Research output: Contribution to journalArticle

Adipose Tissue
Macrophages
CC Chemokines
Ligands
Mesenchymal Stromal Cells

Immunoelectron microscopic localization of Collagen type XV during human mesenchymal stem cells mineralization

Manferdini, C., Zini, N., Gabusi, E., Paolella, F., Lambertini, E., Penolazzi, L., Piva, R. & Lisignoli, G., Dec 2018, In : Connective Tissue Research. 59, sup1, p. 42-45 4 p.

Research output: Contribution to journalArticle

Stem cells
Mesenchymal Stromal Cells
Collagen
Fibrillar Collagens
Bone Matrix
2017

Adipose stromal cells mediated switching of the pro-inflammatory profile of M1-like macrophages is facilitated by PGE2: in vitro evaluation.

Manferdini, C., Paolella, F., Gabusi, E., Gambari, L., Piacentini, A., Filardo, G., Fleury-Cappellesso, S., Barbero, A., Murphy, M. & Lisignoli, G., Jan 30 2017, In : Osteoarthritis and Cartilage. 25, 7, p. 1161-1171 11 p.

Research output: Contribution to journalArticle

Macrophages
Stromal Cells
Mesenchymal Stromal Cells
Dinoprostone
Interleukin-10

Collagen type XV and the 'osteogenic status'

Lisignoli, G., Lambertini, E., Manferdini, C., Gabusi, E., Penolazzi, L., Paolella, F., Angelozzi, M., Casagranda, V. & Piva, R., 2017, (Accepted/In press) In : Journal of Cellular and Molecular Medicine. 21, 9, p. 2236-2244 9 p.

Research output: Contribution to journalArticle

Collagen
Mesenchymal Stromal Cells
Calcium
Extracellular Matrix
Minerals
Cystathionine
Lyases
Osteoblasts
Mesenchymal Stromal Cells
Osteogenesis
Osteochondritis Dissecans
Knee
Bone
Joints
Cartilage
Osteochondritis Dissecans
Knee
Bone
Joints
Cartilage
2016

From osteoarthritic synovium to synovialderived cells characterization: Synovial macrophages are key effector cells

Manferdini, C., Paolella, F., Gabusi, E., Silvestri, Y., Gambari, L., Cattini, L., Filardo, G., Fleury-Cappellesso, S. & Lisignoli, G., 2016, In : Arthritis Research and Therapy. 18, 1, 83.

Research output: Contribution to journalArticle

Synovial Membrane
Macrophages
Fibroblasts
Synovitis
Interleukin-6

Specific inductive potential of a novel nanocomposite biomimetic biomaterial for osteochondral tissue regeneration.

Manferdini, C., Cavallo, C., Grigolo, B., Fiorini, M., Nicoletti, A., Gabusi, E., Zini, N., Pressato, D., Facchini, A. & Lisignoli, G., May 2016, In : Journal of Tissue Engineering and Regenerative Medicine. p. 374-391 17 p.

Research output: Contribution to journalArticle

Open Access
Nanocomposites
Tissue regeneration
Biomimetics
Biocompatible Materials
Scaffolds (biology)
2015

Age-independent effects of hyaluronan amide derivative and growth hormone on human osteoarthritic chondrocytes

Gabusi, E., Paolella, F., Manferdini, C., Gambari, L., Schiavinato, A. & Lisignoli, G., Nov 2 2015, In : Connective Tissue Research. 56, 6, p. 440-451 12 p.

Research output: Contribution to journalArticle

Human Growth Hormone
Hyaluronic Acid
Chondrocytes
Amides
Growth Hormone

Lack of anti-inflammatory and anti-catabolic effects on basal inflamed osteoarthritic chondrocytes or synoviocytes by adipose stem cell-conditioned medium

Manferdini, C., Maumus, M., Gabusi, E., Paolella, F., Grassi, F., Jorgensen, C., Fleury-Cappellesso, S., Noël, D. & Lisignoli, G., Nov 1 2015, In : Osteoarthritis and Cartilage. 23, 11, p. 2045-2057 13 p.

Research output: Contribution to journalArticle

Conditioned Culture Medium
Chondrocytes
Stem cells
Anti-Inflammatory Agents
Stem Cells

Slug transcription factor and nuclear Lamin B1 are upregulated in osteoarthritic chondrocytes

Piva, R., Lambertini, E., Manferdini, C., Capanni, C., Penolazzi, L., Gabusi, E., Paolella, F., Lolli, A., Angelozzi, M., Lattanzi, G. & Lisignoli, G., Jul 1 2015, In : Osteoarthritis and Cartilage. 23, 7, p. 1226-1230 5 p.

Research output: Contribution to journalArticle

Transcription factors
Cartilage
Chondrocytes
Gastropoda
Osteoarthritis
2014

Chondrogenic potential of slug-depleted human mesenchymal stem cells

Lisignoli, G., Manferdini, C., Lambertini, E., Zini, N., Angelozzi, M., Gabusi, E., Gambari, L., Penolazzi, L., Lolli, A., Facchini, A. & Piva, R., 2014, In : Tissue Engineering - Part A. 20, 19-20, p. 2795-2805 11 p.

Research output: Contribution to journalArticle

Gastropoda
Stem cells
Mesenchymal Stromal Cells
Transcription factors
Small Interfering RNA
2013

Adipose-derived mesenchymal stem cells exert antiinflammatory effects on chondrocytes and synoviocytes from osteoarthritis patients through prostaglandin E2

Manferdini, C., Maumus, M., Gabusi, E., Piacentini, A., Filardo, G., Peyrafitte, J. A., Jorgensen, C., Bourin, P., Fleury-Cappellesso, S., Facchini, A., Noël, D. & Lisignoli, G., May 2013, In : Arthritis and Rheumatism. 65, 5, p. 1271-1281 11 p.

Research output: Contribution to journalArticle

Chondrocytes
Mesenchymal Stromal Cells
Dinoprostone
Osteoarthritis
Anti-Inflammatory Agents

Adipose mesenchymal stem cells protect chondrocytes from degeneration associated with osteoarthritis

Maumus, M., Manferdini, C., Toupet, K., Peyrafitte, J. A., Ferreira, R., Facchini, A., Gabusi, E., Bourin, P., Jorgensen, C., Lisignoli, G. & Noël, D., Sep 2013, In : Stem Cell Research. 11, 2, p. 834-844 11 p.

Research output: Contribution to journalArticle

Chondrocytes
Mesenchymal Stromal Cells
Osteoarthritis
Stem Cells
Thrombospondin 1

Specific inductive potential of a novel nanocomposite biomimetic biomaterial for osteochondral tissue regeneration

Manferdini, C., Cavallo, C., Grigolo, B., Fiorini, M., Nicoletti, A., Gabusi, E., Zini, N., Pressato, D., Facchini, A. & Lisignoli, G., 2013, (Accepted/In press) In : Journal of Tissue Engineering and Regenerative Medicine.

Research output: Contribution to journalArticle

Nanocomposites
Tissue regeneration
Biomimetics
Biocompatible Materials
Scaffolds (biology)

T cell subsets differently regulate osteogenic differentiation of human mesenchymal stromal cells in vitro

Grassi, F., Cattini, L., Gambari, L., Manferdini, C., Piacentini, A., Gabusi, E., Facchini, A. & Lisignoli, G., 2013, (Accepted/In press) In : Journal of Tissue Engineering and Regenerative Medicine.

Research output: Contribution to journalArticle

T-cells
T-Lymphocyte Subsets
Mesenchymal Stromal Cells
Cells
T-Lymphocytes
2012

Extracellular calcium chronically induced human osteoblasts effects: Specific modulation of osteocalcin and collagen type XV

Gabusi, E., Manferdini, C., Grassi, F., Piacentini, A., Cattini, L., Filardo, G., Lambertini, E., Piva, R., Zini, N., Facchini, A. & Lisignoli, G., Aug 2012, In : Journal of Cellular Physiology. 227, 8, p. 3151-3161 11 p.

Research output: Contribution to journalArticle

Osteocalcin
Osteoblasts
Collagen
Modulation
Calcium

Role of slug transcription factor in human mesenchymal stem cells

Torreggiani, E., Lisignoli, G., Manferdini, C., Lambertini, E., Penolazzi, L., Vecchiatini, R., Gabusi, E., Chieco, P., Facchini, A., Gambari, R. & Piva, R., 2012, In : Journal of Cellular and Molecular Medicine. 16, 4, p. 740-751 12 p.

Research output: Contribution to journalArticle

Mesenchymal Stromal Cells
Gastropoda
Transcription Factors
Wharton Jelly
Aptitude
2011

Chemical-physical properties and in vitro cell culturing of a novel biphasic bio-mimetic scaffold for osteo-chondral tissue regeneration.

Grigolo, B., Fiorini, M., Manferdini, C., Cavallo, C., Gabusi, E., Zini, N., Dolcini, L., Nicoletti, A., Pressato, D., Facchini, A. & Lisignoli, G., Apr 2011, In : Journal of Biological Regulators and Homeostatic Agents. 25, 2 Suppl

Research output: Contribution to journalArticle

Mesenchymal Stromal Cells
Cartilage
Regeneration
Chitosan
Durapatite

Evidence of specific characteristics and osteogenic potentiality in bone cells from Tibia

Manferdini, C., Gabusi, E., Grassi, F., Piacentini, A., Cattini, L., Zini, N., Filardo, G., Facchini, A. & Lisignoli, G., Oct 2011, In : Journal of Cellular Physiology. 226, 10, p. 2675-2682 8 p.

Research output: Contribution to journalArticle

Osteoblasts
Tibia
Mesenchymal Stromal Cells
Bone
Bone and Bones

Slug contributes to the regulation of CXCL12 expression in human osteoblasts

Piva, R., Manferdini, C., Lambertini, E., Torreggiani, E., Penolazzi, L., Gambari, R., Pastore, A., Pelucchi, S., Gabusi, E., Piacentini, A., Filardo, G., Facchini, A. & Lisignoli, G., May 1 2011, In : Experimental Cell Research. 317, 8, p. 1159-1168 10 p.

Research output: Contribution to journalArticle

Gastropoda
Osteoblasts
Bone and Bones
CXCR4 Receptors
Bone Regeneration

T cell suppression by osteoclasts in vitro

Grassi, F., Manferdini, C., Cattini, L., Piacentini, A., Gabusi, E., Facchini, A. & Lisignoli, G., Apr 2011, In : Journal of Cellular Physiology. 226, 4, p. 982-990 9 p.

Research output: Contribution to journalArticle

T-cells
Osteoclasts
T-Lymphocytes
In Vitro Techniques
Apoptosis

Transcription factor decoy against NFATc1 in human primary osteoblasts

Penolazzi, L., Lisignoli, G., Lambertini, E., Torreggiani, E., Manferdini, C., Lolli, A., Vecchiatini, R., Ciardo, F., Gabusi, E., Facchini, A., Gambari, R. & Piva, R., Aug 2011, In : International Journal of Molecular Medicine. 28, 2, p. 199-206 8 p.

Research output: Contribution to journalArticle

NFATC Transcription Factors
Osteoblasts
Transcription Factors
Theoretical Models
Chromatin Immunoprecipitation
2010

Bone osteoblastic and mesenchymal stromal cells lack primarily tumoral features in multiple myeloma patients

Giuliani, N., Lisignoli, G., Novara, F., Storti, P., Zaffaroni, N., Villa, R., Sammarelli, G., Agnelli, L., Todoerti, K., Bernardo, M. E., Manferdini, C., Colla, S., Abeltino, M., Bolzoni, M., Rocci, A., Gabusi, E., Palumbo, A., Zuffardi, O., Neri, A. & Rizzoli, V., Jul 2010, In : Leukemia. 24, 7, p. 1368-1370 3 p.

Research output: Contribution to journalArticle

Mineralization behavior with mesenchymal stromal cells in a biomimetic hyaluronic acid-based scaffold

Manferdini, C., Guarino, V., Zini, N., Raucci, M. G., Ferrari, A., Grassi, F., Gabusi, E., Squarzoni, S., Facchini, A., Ambrosio, L. & Lisignoli, G., May 2010, In : Biomaterials. 31, 14, p. 3986-3996 11 p.

Research output: Contribution to journalArticle

Hyaluronic acid
Biomimetics
Hyaluronic Acid
Scaffolds (biology)
Mesenchymal Stromal Cells
2009

Slug gene expression supports human osteoblast maturation

Lambertini, E., Lisignoli, G., Torreggiani, E., Manferdini, C., Gabusi, E., Franceschetti, T., Penolazzi, L., Gambari, R., Facchini, A. & Piva, R., Nov 2009, In : Cellular and Molecular Life Sciences. 66, 22, p. 3641-3653 13 p.

Research output: Contribution to journalArticle

Gastropoda
Osteoblasts
Gene Expression
Catenins
Osteopontin
2008

Diagnostic role of circulating free plasma DNA detection in patients with localized prostate cancer

Altimari, A., Grigioni, A. D. E., Benedettini, E., Gabusi, E., Schiavina, R., Martinelli, A., Morselli-Labate, A. M., Martorana, G., Grigioni, W. F. & Fiorentino, M., May 2008, In : American Journal of Clinical Pathology. 129, 5, p. 756-762 7 p.

Research output: Contribution to journalArticle

Prostatic Neoplasms
DNA
Methylation
Genes
ROC Curve

Quantification of free plasma DNA before and after chemotherapy in patients with advanced epithelial ovarian cancer

Capizzi, E., Gabusi, E., Grigioni, A. D., De Iaco, P., Rosati, M., Zamagni, C. & Fiorentino, M., Mar 2008, In : Diagnostic Molecular Pathology. 17, 1, p. 34-38 5 p.

Research output: Contribution to journalArticle

Drug Therapy
DNA
Taxoids
Ovariectomy
Platinum

Real time RT-PCR approach for the evaluation of ERBB2 overexpression in breast cancer archival samples: A comparative study with FISH, SISH, and immunohistochemistry

Capizzi, E., Gruppioni, E., Grigioni, A. D. E., Gabusi, E., Grassigli, A., Grigioni, W. F. & Fiorentino, M., Dec 2008, In : Diagnostic Molecular Pathology. 17, 4, p. 220-226 7 p.

Research output: Contribution to journalArticle

Real-Time Polymerase Chain Reaction
Immunohistochemistry
Breast Neoplasms
Polymerase Chain Reaction
Medical Oncology
2006

Two Years' Experience of Acute Rejection Monitoring of Intestinal Transplant Recipients by Real-Time PCR Assessment of Granzyme B and Perforin Up-Regulation: Considerations on Diagnostic Accuracy

Corti, B., Altimari, A., Gabusi, E., Pinna, A. D., Gruppioni, E., Lauro, A., Pirini, M. G., Fiorentino, M., Ridolfi, L., Grigioni, W. F. & Grigioni, A. D., Jul 2006, In : Transplantation Proceedings. 38, 6, p. 1726-1727 2 p.

Research output: Contribution to journalArticle

Real-Time Polymerase Chain Reaction
Up-Regulation
Endoscopy
Histology
Transplantation
2005

Application of a fluorescent PCR method for molecular diagnosis of posttransplant lymphoproliferative disorders on routine tissue sections

Gruppioni, E., Corti, B., Altimari, A., Gabusi, E., Panza, E., Grazi, G. L., Pinna, D. A., De Ruvo, N., Fiorentino, M., Grigioni, W. F. & Grigioni, A. D. E., Sep 2005, In : Diagnostic Molecular Pathology. 14, 3, p. 170-176 7 p.

Research output: Contribution to journalArticle

Lymphoproliferative Disorders
Polymerase Chain Reaction
Gene Rearrangement
DNA
Lymphoma

II patologo e la sicurezza del trapianto: il controllo istologico.

Translated title of the contribution: The pathologist and transplant safety: the histologic controlAltimari, A., Gruppioni, E., Gabusi, E., Benedettini, E., Fiorentino, M., Corti, B., Pirini, M. G., Grigioni, W. F. & D'Errico Grigioni, A., Aug 2005, In : Pathologica. 97, 4, p. 196 1 p.

Research output: Contribution to journalArticle

Potential of real-time PCR assessment of granzyme B and perforin up-regulation for rejection monitoring in intestinal transplant recipients

Corti, B., Altimari, A., Gabusi, E., Pinna, A. D., Lauro, A., Morselli-Labate, A. M., Gruppioni, E., Pirini, M. G., Fiorentino, M., Ridolfi, L., Grigioni, W. F. & D'Errico-Grigioni, A., Dec 2005, In : Transplantation Proceedings. 37, 10, p. 4467-4471 5 p.

Research output: Contribution to journalArticle

Real-Time Polymerase Chain Reaction
Up-Regulation
Immunohistochemistry
Immunosuppressive Agents
Rejection (Psychology)
2004

Detection of the M30 Neoepitope as a New Tool to Quantify Liver Apoptosis: Timing and Patterns of Positivity on Frozen and Paraffin-Embedded Sections

Grassi, A., Susca, M., Ferri, S., Gabusi, E., D'Errico, A., Farina, G., Maccariello, S., Zauli, D., Bianchi, F. B. & Ballardini, G., Feb 2004, In : American Journal of Clinical Pathology. 121, 2, p. 211-219 9 p.

Research output: Contribution to journalArticle

Paraffin
Apoptosis
Liver
Keratins
Epithelial Cells

Molecular monitoring of organ recipients from cancer-affected donors by detection of circulating tumor cells

Gabusi, E., Corti, B., D'Errico, A., Ridolfi, L., Ercolani, G., Venettoni, S., Costa, A. N. & Grigioni, W. F., Jun 2004, In : Transplantation Proceedings. 36, 5, p. 1344-1347 4 p.

Research output: Contribution to journalArticle

Circulating Neoplastic Cells
Tissue Donors
Polymerase Chain Reaction
Neoplasms
Kidney

Predictive Value of Biological Markers for Hepatocellular Carcinoma Patients Treated with Orthotopic Liver Transplantation

Fiorentino, M., Altimari, A., Ravaioli, M., Gruppioni, E., Gabusi, E., Corti, B., Vivarelli, M., Bringuier, P. P., Scoazec, J. Y., Grigioni, W. F. & D'Errico-Grigioni, A., Mar 1 2004, In : Clinical Cancer Research. 10, 5, p. 1789-1795 7 p.

Research output: Contribution to journalArticle

Catenins
Liver Transplantation
Hepatocellular Carcinoma
Biomarkers
Recurrence

Thorough intraoperative analysis of breast sentinel lymph node biopsies: Histologic and immunohistochemical findings

D'Errico, A., Grassigli, A., Gruppioni, E., Fiorentino, M., Corti, B., Gabusi, E., Morselli-Labate, A. M. & Grigioni, W. F., Mar 2004, In : Surgery. 135, 3, p. 248-254 7 p.

Research output: Contribution to journalArticle

Sentinel Lymph Node Biopsy
Breast
Keratins
Lymphangitis
Neoplasm Micrometastasis
2003

Granzyme B and perforin as predictive markers for acute rejection in human intestinal transplantation

D'Errico, A., Corti, B., Pinna, A. D., Altimari, A., Gruppioni, E., Gabusi, E., Fiorentino, M., Bagni, A. & Grigioni, W. F., Dec 2003, In : Transplantation Proceedings. 35, 8, p. 3061-3065 5 p.

Research output: Contribution to journalArticle

Transplantation
Transplants
Biopsy
Granzymes
Perforin

Increased expression of p16(INK4a) and p27(Kip1) cyclin-dependent kinase inhibitor genes in aging human kidney and chronic allograft nephropathy

Chkhotua, A. B., Gabusi, E., Altimari, A., D'Errico, A., Yakubovich, M., Vienken, J., Stefoni, S., Chieco, P., Yussim, A. & Grigioni, W. F., Jun 1 2003, In : American Journal of Kidney Diseases. 41, 6, p. 1303-1313 11 p.

Research output: Contribution to journalArticle

Cyclin-Dependent Kinase Inhibitor p27
Allografts
Kidney
Genes
Transplants

Increased expression of p21(WAF1/CIP1) CDKI gene in chronic allograft nephropathy correlating with the number of acute rejection episodes

Chkhotua, A. B., Altimari, A., Gabusi, E., D'Errico, A., Yakubovich, M., Vienken, J., Stefoni, S., Chieco, P., Yussim, A. & Grigioni, W. F., Mar 2003, In : Transplantation Proceedings. 35, 2, p. 655-658 4 p.

Research output: Contribution to journalArticle

Increased expression of p21 (WAF1/CIP1) cyclin-dependent kinase (CDK) inhibitor gene in chronic allograft nephropathy correlates with the number of acute rejection episodes

Chkhotua, A. B., Altimari, A., Gabusi, E., D'Errico, A., Stefoni, S., Chieco, P., Yakubovich, M., Vienken, J., Yussim, A. & Grigioni, W. F., Aug 1 2003, In : Transplant International. 16, 8, p. 600-604 5 p.

Research output: Contribution to journalArticle

Cyclin-Dependent Kinases
Allografts
Kidney
Genes
HLA Antigens