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Research Output 2018 2020

2020

Alveolar haemorrhage in ANCA-associated vasculitis: Long-term outcome and mortality predictors

The Italian Study Group on Lung Involvement in Rheumatic Diseases and the Italian Vasculitis Study Group, Jan 1 2020, (Accepted/In press) In : Journal of Autoimmunity. 102397.

Research output: Contribution to journalArticle

Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis
Hemorrhage
Mortality
Cause of Death
Antineutrophil Cytoplasmic Antibodies
2019

Amplifying the concept of psoriatic arthritis: The role of autoimmunity in systemic psoriatic disease

Chimenti, M. S., Caso, F., Alivernini, S., De Martino, E., Costa, L., Tolusso, B., Triggianese, P., Conigliaro, P., Gremese, E., Scarpa, R. & Perricone, R., Jun 2019, In : Autoimmunity Reviews. 18, 6, p. 565-575 11 p.

Research output: Contribution to journalReview article

Psoriatic Arthritis
Autoimmunity
Synovitis
Joints
Tunica Intima
Validation Studies
Interstitial Lung Diseases
Rheumatoid Arthritis
Tomography
Equipment and Supplies

Diagnostic accuracy of a velcro sound detector (VECTOR) for interstitial lung disease in rheumatoid arthritis patients: The InSPIRAtE validation study (INterStitial pneumonia in rheumatoid ArThritis with an electronic device)

Manfredi, A., Cassone, G., Cerri, S., Venerito, V., Fedele, A. L., Trevisani, M., Furini, F., Addimanda, O., Pancaldi, F., Della Casa, G., D'Amico, R., Vicini, R., Sandri, G., Torricelli, P., Celentano, I., Bortoluzzi, A., Malavolta, N., Meliconi, R., Iannone, F., Gremese, E. & 3 others, Luppi, F., Salvarani, C. & Sebastiani, M., Jun 20 2019, In : BMC Pulmonary Medicine. 19, 1

Research output: Contribution to journalArticle

Differential synovial tissue biomarkers among psoriatic arthritis and rheumatoid factor/anti-citrulline antibody-negative rheumatoid arthritis

Alivernini, S., Bruno, D., Tolusso, B., Bui, L., Petricca, L., Gigante, M. R., Birra, D., Fedele, A. L., Peluso, G., Federico, F., Ferraccioli, G. & Gremese, E., May 9 2019, In : Arthritis research & therapy. 21, 1, p. 116

Research output: Contribution to journalArticle

Citrulline
Psoriatic Arthritis
Rheumatoid Factor
Anti-Idiotypic Antibodies
Rheumatoid Arthritis

Early vedolizumab trough levels predict treatment persistence over the first year in inflammatory bowel disease

Guidi, L., Pugliese, D., Tonucci, T. P., Bertani, L., Costa, F., Privitera, G., Tolusso, B., Di Mario, C., Albano, E., Tapete, G., Gremese, E., Papa, A., Gasbarrini, A., Rapaccini, G. L. & Armuzzi, A., Nov 2019, In : United Eur. Gastroenterol. J.. 7, 9, p. 1189-1197 9 p.

Research output: Contribution to journalArticle

Inflammatory Bowel Diseases
Therapeutics
vedolizumab
Observational Studies
Prospective Studies

JAK inhibition by methotrexate (and csDMARDs) may explain clinical efficacy as monotherapy and combination therapy

Gremese, E., Alivernini, S., Tolusso, B., Zeidler, M. P. & Ferraccioli, G., Nov 2019, In : Journal of Leukocyte Biology. 106, 5, p. 1063-1068 6 p.

Research output: Contribution to journalReview article

Methotrexate
leflunomide
Macrophages
Polymyalgia Rheumatica
Therapeutics

Long-term retention rate of anakinra in adult onset Still’s disease and predictive factors for treatment response

Vitale, A., Cavalli, G., Colafrancesco, S., Priori, R., Valesini, G., Argolini, L. M., Baldissera, E., Bartoloni, E., Cammelli, D., Canestrari, G., Sota, J., Cavallaro, E., Massaro, M. G., Ruscitti, P., Cipriani, P., De Marchi, G., De Vita, S., Emmi, G., Ferraccioli, G., Frassi, M. & 28 others, Gerli, R., Gremese, E., Iannone, F., Lapadula, G., Lopalco, G., Manna, R., Mathieu, A., Montecucco, C., Mosca, M., Piazza, I., Piga, M., Pontikaki, I., Romano, M., Rossi, S., Rossini, M., Silvestri, E., Stagnaro, C., Talarico, R., Tincani, A., Viapiana, O., Vitiello, G., Galozzi, P., Sfriso, P., Gaggiano, C., Rigante, D., Dagna, L., Giacomelli, R. & Cantarini, L., Jan 1 2019, In : Frontiers in Pharmacology. 10, APR, 296.

Research output: Contribution to journalArticle

Open Access
Adult-Onset Still's Disease
Interleukin 1 Receptor Antagonist Protein
Antirheumatic Agents
Therapeutics
Joints

Measuring the T-cell down-regulation of TCR-zeta, ZAP-70 and CD28 in arthritis patients: An old tool for new biomarkers

Zizzo, G., De Santis, M., Bosello, S., Tolusso, B., Alivernini, S., De Luca, G., Gremese, E. & Ferraccioli, G., Dec 2019, In : European Journal of Immunology. 49, 12, p. 2195-2203 9 p.

Research output: Contribution to journalArticle

T-Cell Antigen Receptor
Arthritis
ametantrone
Down-Regulation
Biomarkers

Measuring the T-cell down-regulation of TCR-zeta, ZAP-70 and CD28 in arthritis patients: An old tool for new biomarkers

Zizzo, G., De Santis, M., Bosello, S., Tolusso, B., Alivernini, S., De Luca, G., Gremese, E. & Ferraccioli, G., Dec 2019, In : European Journal of Immunology. 49, 12, p. 2195-2203 9 p.

Research output: Contribution to journalArticle

T-Cell Antigen Receptor
Arthritis
ametantrone
Down-Regulation
Biomarkers

Overweight/obesity affects histological features and inflammatory gene signature of synovial membrane of Rheumatoid Arthritis

Alivernini, S., Tolusso, B., Gigante, M. R., Petricca, L., Bui, L., Fedele, A. L., Di Mario, C., Benvenuto, R., Federico, F., Ferraccioli, G. & Gremese, E., Jul 18 2019, In : Scientific Reports. 9, 1, p. 10420

Research output: Contribution to journalArticle

Synovial Membrane
Rheumatoid Arthritis
Obesity
Genes
Antirheumatic Agents

Quantitative and semi-quantitative computed tomography analysis of interstitial lung disease associated with systemic sclerosis: A longitudinal evaluation of pulmonary parenchyma and vessels

Occhipinti, M., Bosello, S., Sisti, L. G., Cicchetti, G., de Waure, C., Pirronti, T., Ferraccioli, G., Gremese, E. & Larici, A. R., 2019, In : PLoS One. 14, 3, p. e0213444

Research output: Contribution to journalArticle

Pulmonary diseases
Systemic Scleroderma
Interstitial Lung Diseases
sclerosis
computed tomography

Real-life effectiveness of ustekinumab in inflammatory bowel disease patients with concomitant psoriasis or psoriatic arthritis: An IG-IBD study

Pugliese, D., Daperno, M., Fiorino, G., Savarino, E., Mosso, E., Biancone, L., Testa, A., Sarpi, L., Cappello, M., Bodini, G., Caprioli, F., Festa, S., Laino, G., Maconi, G., Mazzuoli, S., Mocci, G., Sartini, A., D'Amore, A., Alivernini, S., Gremese, E. & 1 others, Armuzzi, A., Jan 1 2019, In : Digestive and Liver Disease. 51, 7, p. 972-977

Research output: Contribution to journalArticle

Psoriatic Arthritis
Inflammatory Bowel Diseases
Psoriasis
Ustekinumab
Therapeutics

Real-life effectiveness of ustekinumab in inflammatory bowel disease patients with concomitant psoriasis or psoriatic arthritis: An IG-IBD study

Pugliese, D., Daperno, M., Fiorino, G., Savarino, E., Mosso, E., Biancone, L., Testa, A., Sarpi, L., Cappello, M., Bodini, G., Caprioli, F., Festa, S., Laino, G., Maconi, G., Mazzuoli, S., Mocci, G., Sartini, A., D'Amore, A., Alivernini, S., Gremese, E. & 1 others, Armuzzi, A., Jul 2019, In : Digestive and Liver Disease. 51, 7, p. 972-977 6 p.

Research output: Contribution to journalArticle

Psoriatic Arthritis
Inflammatory Bowel Diseases
Psoriasis
Ustekinumab
Therapeutics

Real-life effectiveness of ustekinumab in inflammatory bowel disease patients with concomitant psoriasis or psoriatic arthritis: An IG-IBD study

Pugliese, D., Daperno, M., Fiorino, G., Savarino, E., Mosso, E., Biancone, L., Testa, A., Sarpi, L., Cappello, M., Bodini, G., Caprioli, F., Festa, S., Laino, G., Maconi, G., Mazzuoli, S., Mocci, G., Sartini, A., D'Amore, A., Alivernini, S., Gremese, E. & 1 others, Armuzzi, A., Jul 2019, In : Digestive and Liver Disease. 51, 7, p. 972-977 6 p.

Research output: Contribution to journalArticle

Psoriatic Arthritis
Inflammatory Bowel Diseases
Psoriasis
Ustekinumab
Therapeutics

Selective Inhibitors of T Cell Receptor Recognition of Antigen-MHC Complexes for Rheumatoid Arthritis

Ria, F., Pirolli, D., Di Sante, G., Righino, B., Gremese, E., Gervasoni, J., Nicolò, C., Giardina, B., Ferraccioli, G. & De Rosa, M. C., Apr 11 2019, In : ACS Medicinal Chemistry Letters. 10, 4, p. 644-649 6 p.

Research output: Contribution to journalArticle

T-Cell Antigen Receptor
Rheumatoid Arthritis
Antigens
Collagen Type II
Proteins

The B side of rheumatoid arthritis pathogenesis

Alivernini, S., Tolusso, B., Fedele, A. L., Di Mario, C., Ferraccioli, G. & Gremese, E., Nov 2019, In : Pharmacological Research. 149, p. 104465

Research output: Contribution to journalReview article

Rheumatoid Arthritis
B-Lymphocytes
Inflammation
Autoimmunity
Autoantibodies

Transitional care of young people with juvenile idiopathic arthritis in Italy: results of a Delphi consensus survey

Italian Paediatric Rheumatology Study Group and the Italian Society of Rheumatology, Jul 25 2019, In : Clinical and Experimental Rheumatology.

Research output: Contribution to journalArticle

Juvenile Arthritis
Italy
Rheumatology
Pediatrics
Delivery of Health Care

Transitional care of young people with juvenile idiopathic arthritis in Italy: results of a Delphi consensus survey: Clinical and experimental rheumatology

Ravelli, A., Sinigaglia, L., Cimaz, R., Alessio, M., Breda, L., Cattalini, M., Consolaro, A., Conti, F., Cortis, E., D'Angelo, S., De Benedetti, F., Doria, A., Ferrari, C., Gallizzi, R., Govoni, M., Gremese, E., Iannone, F., La Torre, F., Maggio, M. C., Perricone, R. & 6 others, Pontikaki, I., Rossi, F., Salaffi, F., Simonini, G., Caporali, R. & Rheumatology, I. P. R. S. G. A. T. I. S. O., 2019, In : Clin. Exp. Rheumatol.. 37, 6, p. 1084-1091 8 p.

Research output: Contribution to journalArticle

2018

Abatacept in the treatment of psoriatic arthritis: Biological and clinical profiles of the responders

Zizzo, G., Gremese, E. & Ferraccioli, G., Jul 1 2018, In : Immunotherapy. 10, 9, p. 807-821 15 p.

Research output: Contribution to journalReview article

Psoriatic Arthritis
Antirheumatic Agents
T-Lymphocyte Subsets
Therapeutics
T-Lymphocytes

Anti-LL37 Antibodies Are Present in Psoriatic Arthritis (PsA) Patients: New Biomarkers in PsA

Frasca, L., Palazzo, R., Chimenti, M. S., Alivernini, S., Tolusso, B., Bui, L., Botti, E., Giunta, A., Bianchi, L., Petricca, L., Auteri, S. E., Spadaro, F., Fonti, G. L., Falchi, M., Evangelista, A., Marinari, B., Pietraforte, I., Spinelli, F. R., Colasanti, T., Alessandri, C. & 6 others, Conti, F., Gremese, E., Costanzo, A., Valesini, G., Perricone, R. & Lande, R., 2018, In : Frontiers in Immunology. 9, p. 1936

Research output: Contribution to journalArticle

Psoriatic Arthritis
Anti-Idiotypic Antibodies
Biomarkers
Psoriasis
Synovial Fluid

Anti-LL37 antibodies are present in psoriatic arthritis (PsA) patients: New biomarkers in PsA

Frasca, L., Palazzo, R., Chimenti, M. S., Alivernini, S., Tolusso, B., Bui, L., Botti, E., Giunta, A., Bianchi, L., Petricca, L., Auteri, S. E., Spadaro, F., Fonti, G. L., Falchi, M., Evangelista, A., Marinari, B., Pietraforte, I., Spinelli, F. R., Colasanti, T., Alessandri, C. & 6 others, Conti, F., Gremese, E., Costanzo, A., Valesini, G., Perricone, R. & Lande, R., 2018, In : Frontiers in Immunology. 9, SEP

Research output: Contribution to journalArticle

Psoriatic Arthritis
Anti-Idiotypic Antibodies
Biomarkers
Psoriasis
Synovial Fluid

Anti-LL37 antibodies are present in psoriatic arthritis (PsA) patients: New biomarkers in PsA

Frasca, L., Palazzo, R., Chimenti, M. S., Alivernini, S., Tolusso, B., Bui, L., Botti, E., Giunta, A., Bianchi, L., Petricca, L., Auteri, S. E., Spadaro, F., Fonti, G. L., Falchi, M., Evangelista, A., Marinari, B., Pietraforte, I., Spinelli, F. R., Colasanti, T., Alessandri, C. & 6 others, Conti, F., Gremese, E., Costanzo, A., Valesini, G., Perricone, R. & Lande, R., 2018, In : Frontiers in Immunology. 9, SEP

Research output: Contribution to journalArticle

Anti-Müllerian hormone serum levels in systemic lupus erythematosus patients: Influence of the disease severity and therapy on the ovarian reserve

Di Mario, C., Petricca, L., Gigante, M. R., Barini, A., Barini, A., Varriano, V., Paglionico, A., Cattani, P., Ferraccioli, G., Tolusso, B. & Gremese, E., Oct 15 2018, In : Endocrine.

Research output: Contribution to journalArticle

Systemic Lupus Erythematosus
Hormones
Antirheumatic Agents
Serum
Cyclophosphamide

Cardiac troponin T and NT-proBNP as diagnostic and prognostic biomarkers of primary cardiac involvement and disease severity in systemic sclerosis: A prospective study

Bosello, S., De Luca, G., Berardi, G., Canestrari, G., de Waure, C., Gabrielli, F. A., Di Mario, C., Forni, F., Gremese, E. & Ferraccioli, G., Jan 1 2018, (Accepted/In press) In : European Journal of Internal Medicine.

Research output: Contribution to journalArticle

Troponin T
Systemic Scleroderma
Heart Diseases
Biomarkers
Prospective Studies

Characterization of inflammatory cell infiltrate of scleroderma skin: B cells and skin score progression

Bosello, S., Angelucci, C., Lama, G., Alivernini, S., Proietti, G., Tolusso, B., Sica, G., Gremese, E. & Ferraccioli, G., Apr 18 2018, In : Arthritis Research and Therapy. 20, 1, 75.

Research output: Contribution to journalArticle

B-Lymphocytes
Skin
Systemic Scleroderma
Biopsy
Cell Count

Chemerin and PEDF Are Metaflammation-Related Biomarkers of Disease Activity and Obesity in Rheumatoid Arthritis

Tolusso, B., Gigante, M. R., Alivernini, S., Petricca, L., Fedele, A. L., Di Mario, C., Aquilanti, B., Magurano, M. R., Ferraccioli, G. & Gremese, E., 2018, In : Frontiers in Medicine. 5, p. 207

Research output: Contribution to journalArticle

Rheumatoid Arthritis
Obesity
Biomarkers
Body Mass Index
Inflammation

Correction to: Anti-Müllerian hormone serum levels in systemic lupus erythematosus patients: influence of the disease severity and therapy on the ovarian reserve (Endocrine, (2018), 10.1007/s12020-018-1783-1)

Di Mario, C., Petricca, L., Gigante, M. R., Barini, A., Barini, A., Varriano, V., Paglionico, A., Cattani, P., Ferraccioli, G., Tolusso, B. & Gremese, E., Jan 1 2018, (Accepted/In press) In : Endocrine.

Research output: Contribution to journalArticle

Systemic Lupus Erythematosus
Names
Hormones
Serum
Therapeutics

Driving chronicity in rheumatoid arthritis: perpetuating role of myeloid cells

Alivernini, S., Tolusso, B., Ferraccioli, G., Gremese, E., Kurowska-Stolarska, M. & McInnes, I. B., Jul 2018, In : Clinical and Experimental Immunology. 193, 1, p. 13-23 11 p.

Research output: Contribution to journalReview article

Myeloid Cells
Rheumatoid Arthritis
Inflammation
Leukocytes
Chronic Disease

Free light chains of immunoglobulins in patients with systemic sclerosis: Correlations with lung involvement and inflammatory milieu

Bosello, S., Basile, U., De Lorenzis, E., Gulli, F., Canestrari, G., Napodano, C., Parisi, F., Pocino, K., Di Mario, C., Tolusso, B., Ferraccioli, G. & Gremese, E., Jan 31 2018, (Accepted/In press) In : Journal of Clinical Pathology.

Research output: Contribution to journalArticle

Immunoglobulin Light Chains
Systemic Scleroderma
Light
Lung
B-Lymphocytes
Rheumatoid Factor
Immunoglobulin A
Interleukin-6
Rheumatoid Arthritis
Peptides

MicroRNA-155-at the critical interface of innate and adaptive immunity in arthritis

Alivernini, S., Gremese, E., McSharry, C., Tolusso, B., Ferraccioli, G., McInnes, I. B. & Kurowska-Stolarska, M., Jan 5 2018, In : Frontiers in Immunology. 8, JAN, 1932.

Research output: Contribution to journalReview article

Adaptive Immunity
MicroRNAs
Innate Immunity
Arthritis
Immune System

Paradoxical arthritis occurring during Anti-TNF in patients with inflammatory bowel disease: Histological and immunological features of a complex synovitis

Alivernini, S., Pugliese, D., Tolusso, B., Bui, L., Petricca, L., Guidi, L., Mirone, L., Rapaccini, G. L., Federico, F., Ferraccioli, G., Armuzzi, A. & Gremese, E., Jan 1 2018, In : RMD Open. 4, 1, e000667.

Research output: Contribution to journalArticle

Synovitis
Inflammatory Bowel Diseases
Arthritis
Rheumatoid Factor
Tumor Necrosis Factor-alpha

Prevalence and Determinants of Peripheral Microvascular Endothelial Dysfunction in Rheumatoid Arthritis Patients: A Multicenter Cross-Sectional Study

Erre, G. L., Piga, M., Fedele, A. L., Mura, S., Piras, A., Cadoni, M. L., Cangemi, I., Dessi, M., Di Sante, G., Tolusso, B., Gremese, E., Cauli, A., Mangoni, A. A., Saba, P. S., Carru, C., Ferraccioli, G., Mathieu, A. & Passiu, G., Jan 1 2018, In : Mediators of Inflammation. 2018, 6548715.

Research output: Contribution to journalArticle

Hyperemia
Rheumatoid Arthritis
Cross-Sectional Studies
Regression Analysis
Blood Pressure

Statins and mortality in connective tissue diseases: Should we resume the cardio-rheumatology spirit in our clinics?

Gremese, E., De Lorenzis, E. & Ferraccioli, G. F., Dec 1 2018, In : Journal of Rheumatology. 45, 12, p. 1617-1619 3 p.

Research output: Contribution to journalEditorial

Switch or swap strategy in rheumatoid arthritis patients failing TNF inhibitors? Results of a modified Italian Expert Consensus

Todoerti, M., Favalli, E. G., Iannone, F., Olivieri, I., Benucci, M., Cauli, A., Mathieu, A., Santo, L., Minisola, G., Lapadula, G., Bucci, R., Gremese, E. & Caporali, R., Oct 1 2018, In : Rheumatology (Oxford, England). 57, 57 Suppl 7, p. vii53

Research output: Contribution to journalArticle

Rheumatoid Arthritis
Expert Testimony
Research
Population
Therapeutics

Synovial Predictors of Differentiation to Definite Arthritis in Patients With Seronegative Undifferentiated Peripheral Inflammatory Arthritis: microRNA Signature, Histological, and Ultrasound Features

Alivernini, S., Tolusso, B., Petricca, L., Bui, L., Di Mario, C., Gigante, M. R., Di Sante, G., Benvenuto, R., Fedele, A. L., Federico, F., Ferraccioli, G. & Gremese, E., 2018, In : Frontiers in Medicine. 5, p. 186

Research output: Contribution to journalArticle

MicroRNAs
Arthritis
Psoriatic Arthritis
Polymerase Chain Reaction
Interleukin-6

The influence of comorbidities on the efficacy of tumour necrosis factor inhibitors, and the effect of tumour necrosis factor inhibitors on comorbidities in rheumatoid arthritis: report from a National Consensus Conference

Conti, F., Atzeni, F., Massaro, L., Chiara Gerardi, M., Gremese, E., Passiu, G., Carletto, A., Malavolta, N., Foti, R., Ramonda, R. & Sarzi-Puttini, P., Oct 1 2018, In : Rheumatology (Oxford, England). 57, 57, p. vii11-vii22

Research output: Contribution to journalReview article

Comorbidity
Rheumatoid Arthritis
Consensus
Tumor Necrosis Factor-alpha
Infection

The profiling of axial spondyloarthritis patient candidate to a biologic therapy: Consensus from a Delphi-panel of Italian experts

GISEA Study Group, Dec 2018, In : Autoimmunity Reviews. 17, 12, p. 1251-1258 8 p.

Research output: Contribution to journalReview article

Biological Therapy
Uveitis
Biological Factors
Therapeutics

Therapeutic drug monitoring is more cost-effective than a clinically based approach in the management of loss of response to infliximab in inflammatory bowel disease: An observational multicentre study

Guidi, L., Pugliese, D., Tonucci, T. P., Berrino, A., Tolusso, B., Basile, M., Cantoro, L., Balestrieri, P., Civitelli, F., Bertani, L., Marzo, M., Felice, C., Gremese, E., Costa, F., Viola, F., Cicala, M., Kohn, A., Gasbarrini, A., Rapaccini, G. L., Ruggeri, M. & 1 others, Armuzzi, A., Aug 29 2018, In : Journal of Crohn's and Colitis. 12, 9, p. 1079-1088 10 p.

Research output: Contribution to journalArticle

Drug Monitoring
Inflammatory Bowel Diseases
Multicenter Studies
Observational Studies
Costs and Cost Analysis

Ultrasound assessment as predictor of disease relapse in children and adults with arthritis in clinical stable remission: New findings but still unmet needs

Gremese, E., Fedele, A. L., Alivernini, S. & Ferraccioli, G., Jun 2 2018, (Accepted/In press) In : Annals of the Rheumatic Diseases.

Research output: Contribution to journalArticle