19952020

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2020

Scaffolds for Knee Chondral and Osteochondral Defects: Indications for Different Clinical Scenarios. A Consensus Statement

Filardo, G., Andriolo, L., Angele, P., Berruto, M., Brittberg, M., Condello, V., Chubinskaya, S., de Girolamo, L., Di Martino, A., Di Matteo, B., Gille, J., Gobbi, A., Lattermann, C., Nakamura, N., Nehrer, S., Peretti, G. M., Shabshin, N., Verdonk, P., Zaslav, K. & Kon, E., Jan 15 2020, In : Cartilage. p. 1947603519894729

Research output: Contribution to journalArticle

Vegetable hierarchical structures as template for bone regeneration: New bio-ceramization process for the development of a bone scaffold applied to an experimental sheep model

Filardo, G., Roffi, A., Fey, T., Fini, M., Giavaresi, G., Marcacci, M., Martínez-Fernández, J., Martini, L., Ramírez-Rico, J., Salamanna, F., Sandri, M., Sprio, S., Tampieri, A. & Kon, E., 2020, In : Journal of Biomedical Materials Research - Part B Applied Biomaterials. p. 1-12 12 p.

Research output: Contribution to journalArticle

2019

A Composite Chitosan-Reinforced Scaffold Fails to Provide Osteochondral Regeneration

Roffi, A., Kon, E., Perdisa, F., Fini, M., Di Martino, A., Parrilli, A., Salamanna, F., Sandri, M., Sartori, M., Sprio, S., Tampieri, A., Marcacci, M. & Filardo, G., May 7 2019, In : International Journal of Molecular Sciences. 20, 9, p. 1-14 14 p.

Research output: Contribution to journalArticle

2018

Clinical and Biological Signature of Osteochondritis Dissecans in a Cross-Sectional Study

Gabusi, E., Manferdini, C., Paolella, F., Gambari, L., Kon, E., Filardo, G., Mariani, E. & Lisignoli, G., May 2018, In : BioMed Research International. 2018, p. 1-9 9 p.

Research output: Contribution to journalArticle

Clinical Outcomes of Knee Osteoarthritis Treated With an Autologous Protein Solution Injection: A 1-Year Pilot Double-Blinded Randomized Controlled Trial

Kon, E., Engebretsen, L., Verdonk, P., Nehrer, S. & Filardo, G., Jan 1 2018, In : American Journal of Sports Medicine. 46, 1, p. 171-180 10 p.

Research output: Contribution to journalArticle

Cultures of a human synovial cell line to evaluate platelet-rich plasma and hyaluronic acid effects

Olivotto, E., Merli, G., Assirelli, E., Cavallo, C., Belluzzi, E., Ramonda, R., Favero, M., Filardo, G., Roffi, A., Kon, E. & Grigolo, B., Aug 2018, In : Journal of Tissue Engineering and Regenerative Medicine. 12, 8, p. 1835-1842 8 p.

Research output: Contribution to journalArticle

Effect of microfragmented adipose tissue on osteoarthritic synovial macrophage factors

Paolella, F., Manferdini, C., Gabusi, E., Gambari, L., Filardo, G., Kon, E., Mariani, E. & Lisignoli, G., Sep 6 2018, In : Journal of Cellular Physiology. 234, 4, p. 5044-5055 12 p.

Research output: Contribution to journalArticle

Evaluation of different crosslinking agents on hybrid biomimetic collagen-hydroxyapatite composites for regenerative medicine

Krishnakumar, G. S., Gostynska, N., Dapporto, M., Campodoni, E., Montesi, M., Panseri, S., Tampieri, A., Kon, E., Marcacci, M., Sprio, S. & Sandri, M., Jan 1 2018, In : International Journal of Biological Macromolecules. 106, p. 739-748 10 p.

Research output: Contribution to journalArticle

Novel alginate biphasic scaffold for osteochondral regeneration: an in vivo evaluation in rabbit and sheep models

Filardo, G., Perdisa, F., Gelinsky, M., Despang, F., Fini, M., Marcacci, M., Parrilli, A. P., Roffi, A., Salamanna, F., Sartori, M., Schütz, K. & Kon, E., May 26 2018, In : Journal of Materials Science: Materials in Medicine. 29, 6, p. 1-13 13 p.

Research output: Contribution to journalArticle

Platelet-Rich Plasma Versus Hyaluronic Acid Injections for the Treatment of Knee Osteoarthritis: Results at 5 Years of a Double-Blind, Randomized Controlled Trial

Di Martino, A., Di Matteo, B., Papio, T., Tentoni, F., Selleri, F., Cenacchi, A., Kon, E. & Filardo, G., Dec 13 2018, In : American Journal of Sports Medicine. p. 1-8 8 p.

Research output: Contribution to journalArticle

Treatment of Knee Osteochondritis Dissecans With a Cell-Free Biomimetic Osteochondral Scaffold: Clinical and Imaging Findings at Midterm Follow-up

Perdisa, F., Kon, E., Sessa, A., Andriolo, L., Busacca, M., Marcacci, M. & Filardo, G., Feb 1 2018, In : American Journal of Sports Medicine. 46, 2, p. 314-321 8 p.

Research output: Contribution to journalArticle

2017

3D porous collagen scaffolds reinforced by glycation with ribose for tissue engineering application

Gostynska, N., Shankar Krishnakumar, G., Campodoni, E., Panseri, S., Montesi, M., Sprio, S., Kon, E., Marcacci, M., Tampieri, A. & Sandri, M., Aug 21 2017, In : Biomedical Materials (Bristol). 12, 5, 055002.

Research output: Contribution to journalArticle

3D porous collagen scaffolds reinforced by glycation with ribose for tissue engineering application

Gostynska, N., Shankar Krishnakumar, G., Campodoni, E., Panseri, S., Montesi, M., Sprio, S., Kon, E., Tampieri, A., Sandri, M. & Marcacci, M., Aug 21 2017, In : Biomedical Materials. 12, 5, p. 055002

Research output: Contribution to journalArticle

Age Is Not a Contraindication for Cartilage Surgery: A Critical Analysis of Standardized Outcomes at Long-term Follow-up

Filardo, G., Andriolo, L., Sessa, A., Vannini, F., Ferruzzi, A., Marcacci, M. & Kon, E., Mar 1 2017, In : American Journal of Sports Medicine. 45, 8, p. 1822-1828 7 p.

Research output: Contribution to journalArticle

A multilayer biomaterial for osteochondral regeneration shows superiority vs microfractures for the treatment of osteochondral lesions in a multicentre randomized trial at 2 years

Kon, E., Filardo, G., Brittberg, M., Busacca, M., Condello, V., Engebretsen, L., Marlovits, S., Niemeyer, P., Platzer, P., Posthumus, M., Verdonk, P., Verdonk, R., Victor, J., van der Merwe, W., Widuchowski, W., Zorzi, C. & Marcacci, M., Sep 14 2017, (Accepted/In press) In : Knee Surgery, Sports Traumatology, Arthroscopy. p. 1-12 12 p.

Research output: Contribution to journalArticle

A multilayer biomaterial for osteochondral regeneration shows superiority vs microfractures for the treatment of osteochondral lesions in a multicentre randomized trial at 2 years.

Kon, E., Filardo, G., Brittberg, M., Busacca, M., Condello, V., Engebretsen, L., Marlovits, S., Niemeyer, P., Platzer, P., Posthumus, M., Verdonk, P., Verdonk, R., Victor, J., van der Merwe, W., Widuchowski, W., Zorzi, C. & Marcacci, M., Sep 14 2017, In : Knee Surgery, Sports Traumatology, Arthroscopy. p. 1-12 12 p.

Research output: Contribution to journalArticle

Art in Science: The Artist and The Disease: The Exemplary Cases of Renoir and Toulouse-Lautrec

Di Matteo, B., Tarabella, V., Filardo, G., Tanzi, P., Kon, E., Iacono, F. & Marcacci, M., Aug 7 2017, (Accepted/In press) In : Clinical Orthopaedics and Related Research. p. 1-6 6 p.

Research output: Contribution to journalArticle

Art in Science: The Artist and The Disease: The Exemplary Cases of Renoir and Toulouse-Lautrec

Di Matteo, B., Tarabella, V., Filardo, G., Tanzi, P., Kon, E., Iacono, F. & Marcacci, M., Oct 2017, In : Clinical Orthopaedics and Related Research. 475, 10, p. 2376-2381 6 p.

Research output: Contribution to journalArticle

"Bone Morphogenic Protein augmentation for long bone healing" response to "Clinical need for bone morphogenetic protein".

Krishnakumar, G. S., Roffi, A., Reale, D., Kon, E. & Filardo, G., Sep 3 2017, In : International Orthopaedics. 41, 11, p. 2417-2419 3 p.

Research output: Contribution to journalArticle

Clinical application of bone morphogenetic proteins for bone healing: a systematic review.

Krishnakumar, G. S., Roffi, A., Reale, D., Kon, E. & Filardo, G., Apr 19 2017, In : International Orthopaedics. 41, 6, p. 1073-1083 11 p.

Research output: Contribution to journalArticle

Clinical Outcomes of Knee Osteoarthritis Treated With an Autologous Protein Solution Injection: A 1-Year Pilot Double-Blinded Randomized Controlled Trial.

Kon, E., Engebretsen, L., Verdonk, P., Nehrer, S. & Filardo, G., Oct 1 2017, In : American Journal of Sports Medicine. 46, 1, p. 171-180 10 p.

Research output: Contribution to journalArticle

Evaluation of different crosslinking agents on hybrid biomimetic collagen-hydroxyapatite composites for regenerative medicine.

Shankar Krishnakumar, G., Gostyńska, N., Dapporto, M., Campodoni, E., Montesi, M., Panseri, S., Tampieri, A., Kon, E., Marcacci, M., Sprio, S. & Sandri, M., 2017, In : International Journal of Biological Macromolecules. 106, p. 739-748 10 p.

Research output: Contribution to journalArticle

Implant strategy affects scaffold stability and integrity in cartilage treatment.

Drobnič, M., Perdisa, F., Kon, E., Cefalì, F., Marcacci, M. & Filardo, G., Oct 11 2017, In : Knee Surgery, Sports Traumatology, Arthroscopy. p. 1-10 10 p.

Research output: Contribution to journalArticle

International Meniscus Reconstruction Experts Forum (IMREF) 2015 Consensus Statement on the Practice of Meniscal Allograft Transplantation

Getgood, A., LaPrade, R. F., Verdonk, P., Gersoff, B., Cole, B., Spalding, T., Amis, A., Bin, S. I., Bugbee, W., Caborn, D., Carter, T., Chan, K. M., Cohen, C., Cohen, M., Condello, V., DeBerardino, T., Dirisamer, F., Engebretsen, L., Farr, J. ., Gomoll, A. & 29 others, Harner, C., Heard, M., Hiemstra, L., Kim, J. M., Kon, E., Laggae, K., Lee, B. S., Litchfild, R., Marcacci, M., McCormack, R., McDermott, I., Monlau, J. C., Myers, P., Noyes, F., Patsch, C., Robinson, J., Rodeo, S. R., Seo, S. S., Sherman, S., Siebold, R., Snow, M., Stone, K., Tashman, S., Thompson, P., van Arkel, E., Van Der Merwe, W., Verdonk, R., Williams, A. & Zaffagnini, S., 2017, In : American Journal of Sports Medicine. 45, 5, p. 1195-1205 11 p.

Research output: Contribution to journalArticle

Investigation of different cross-linking approaches on 3D gelatin scaffolds for tissue engineering application: A comparative analysis

Shankar, K. G., Gostynska, N., Montesi, M., Panseri, S., Sprio, S., Kon, E., Marcacci, M., Tampieri, A. & Sandri, M., Feb 1 2017, In : International Journal of Biological Macromolecules. 95, p. 1199-1209 11 p.

Research output: Contribution to journalArticle

One-Step Treatment for Patellar Cartilage Defects With a Cell-Free Osteochondral Scaffold.

Perdisa, F., Filardo, G., Sessa, A., Busacca, M., Zaffagnini, S., Marcacci, M. & Kon, E., Mar 2017, In : American Journal of Sports Medicine. 45, 7, p. 1581-1588 8 p.

Research output: Contribution to journalArticle

Patients control preferences and results in knee arthroplasty

Filardo, G., Roffi, A., Merli, G., Marcacci, T., Berti Ceroni, F., Raboni, D., Kon, E. & Marcacci, M., Feb 1 2017, In : Knee Surgery, Sports Traumatology, Arthroscopy. 25, 2, p. 552-558 7 p.

Research output: Contribution to journalArticle

Ribose mediated crosslinking of collagen-hydroxyapatite hybrid scaffolds for bone tissue regeneration using biomimetic strategies

Krishnakumar, G. S., Gostynska, N., Campodoni, E., Dapporto, M., Montesi, M., Panseri, S., Tampieri, A., Kon, E., Marcacci, M., Sprio, S. & Sandri, M., 2017, In : Materials Science and Engineering C. 77, p. 594-605 12 p.

Research output: Contribution to journalArticle

Ribose mediated crosslinking of collagen-hydroxyapatite hybrid scaffolds for bone tissue regeneration using biomimetic strategies

Krishnakumar, G. S., Gostynska, N., Campodoni, E., Dapporto, M., Montesi, M., Panseri, S., Tampieri, A., Kon, E., Marcacci, M., Sprio, S. & Sandri, S., Aug 1 2017, In : Materials Science and Engineering C. 77, p. 594-605 12 p.

Research output: Contribution to journalArticle

Short-Term Homing of Hyaluronan-Primed Cells: Therapeutic Implications for Osteoarthritis Treatment.

Desando, G., Bartolotti, I., Cavallo, C., Schiavinato, A., Secchieri, C., Kon, E., Filardo, G., Paro, M. & Grigolo, B., Dec 22 2017, In : Tissue Engineering - Part C: Methods. p. 1-13 13 p.

Research output: Contribution to journalArticle

The Role of Three-Dimensional Scaffolds in Treating Long Bone Defects: Evidence from Preclinical and Clinical Literature-A Systematic Review.

Roffi, A., Krishnakumar, G. S., Gostyńska, N., Kon, E., Candrian, C. & Filardo, G., 2017, In : BioMed Research International. p. 1-13 13 p.

Research output: Contribution to journalArticle

Treatment of Knee Osteochondritis Dissecans With a Cell-Free Biomimetic Osteochondral Scaffold: Clinical and Imaging Findings at Midterm Follow-up.

Perdisa, F., Kon, E., Sessa, A., Andriolo, L., Busacca, M., Marcacci, M. & Filardo, G., Nov 1 2017, In : American Journal of Sports Medicine. p. 1-8 8 p.

Research output: Contribution to journalArticle

2016

Aetiology and pathogenesis of bone marrow lesions and osteonecrosis of the knee

Marcacci, M., Andriolo, L., Kon, E., Shabshin, N. & Filardo, G., 2016, In : EFORT Open Reviews.

Research output: Contribution to journalArticle

A novel aragonite-based scaffold for osteochondral regeneration: early experience on human implants and technical developments

Kon, E., Robinson, D., Verdonk, P., Drobnic, M., Patrascu, J. M., Dulic, O., Gavrilovic, G. & Filardo, G., Dec 1 2016, In : Injury. 47, p. S27-S32 6 p.

Research output: Contribution to journalArticle

Anterior cruciate ligament injury: post-traumatic bone marrow oedema correlates with long-term prognosis

Filardo, G., Kon, E., Tentoni, F., Andriolo, L., Di Martino, A., Busacca, M., Di Matteo, B. & Marcacci, M., Jan 1 2016, In : International Orthopaedics. 40, 1, p. 183-190 8 p.

Research output: Contribution to journalArticle

Bone marrow lesions and subchondral bone pathology of the knee

Kon, E., Ronga, M., Filardo, G., Farr, J., Madry, H., Milano, G., Andriolo, L. & Shabshin, N., Apr 13 2016, (Accepted/In press) In : Knee Surgery, Sports Traumatology, Arthroscopy. p. 1-18 18 p.

Research output: Contribution to journalArticle

Chondral and osteochondral operative treatment in early osteoarthritis

Angele, P., Niemeyer, P., Steinwachs, M., Filardo, G., Gomoll, A. H., Kon, E., Zellner, J. & Madry, H., Feb 27 2016, (Accepted/In press) In : Knee Surgery, Sports Traumatology, Arthroscopy. p. 1-10 10 p.

Research output: Contribution to journalArticle

Do cartilage lesions affect the clinical outcome of anterior cruciate ligament reconstruction? A systematic review

Filardo, G., de Caro, F., Andriolo, L., Kon, E., Zaffagnini, S. & Marcacci, M., Apr 4 2016, (Accepted/In press) In : Knee Surgery, Sports Traumatology, Arthroscopy. p. 1-15 15 p.

Research output: Contribution to journalArticle

Early OA: point of no return or a chance for regenerative approaches

Angele, P., Madry, H. & Kon, E., Jun 1 2016, In : Knee Surgery, Sports Traumatology, Arthroscopy. 24, 6, p. 1741-1742 2 p.

Research output: Contribution to journalArticle

Early osteoarthritis of the knee

Madry, H., Kon, E., Condello, V., Peretti, G. M., Steinwachs, M., Seil, R., Berruto, M., Engebretsen, L., Filardo, G. & Angele, P., Mar 21 2016, (Accepted/In press) In : Knee Surgery, Sports Traumatology, Arthroscopy. p. 1-10 10 p.

Research output: Contribution to journalArticle

Early osteoarthritis of the knee

Madry, H., Kon, E., Condello, V., Peretti, G., Steinwachs, M., Seil, R., Berruto, M., Engebretsen, L., Filardo, G. & Angele, P., Mar 21 2016, (Accepted/In press) In : Knee Surgery, Sports Traumatology, Arthroscopy. p. 1-10 10 p.

Research output: Contribution to journalArticle

Early Viscosupplementation after Anterior Cruciate Ligament Reconstruction: A Randomized Controlled Trial

Di Martino, A., Tentoni, F., Di Matteo, B., Cavicchioli, A., Lo Presti, M., Filardo, G., Zaffagnini, S., Marcacci, M. & Kon, E., Oct 1 2016, In : American Journal of Sports Medicine. 44, 10, p. 2572-2578 7 p.

Research output: Contribution to journalArticle

Fabrication and Pilot In Vivo Study of a Collagen-BDDGE-Elastin Core-Shell Scaffold for Tendon Regeneration.

Sandri, M., Filardo, G., Kon, E., Pansieri, S., Montesi, M., Iafisco, M., Savini, E., Sprio, S., Cunha, C., Giavaresi, G., Veronesi, F., Fini, M., Salvatore, L., Sannino, A., Marcacci, M. & Tampieri, A., 2016, In : Frontiers in Bioengineering and Biotechnology.

Research output: Contribution to journalArticle

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Kinesiophobia and depression affect total knee arthroplasty outcome in a multivariate analysis of psychological and physical factors on 200 patients

Filardo, G., Merli, G., Roffi, A., Marcacci, T., Berti Ceroni, F., Raboni, D., Bortolotti, B., Kon, E. & Marcacci, M., Jun 21 2016, (Accepted/In press) In : Knee Surgery, Sports Traumatology, Arthroscopy. p. 1-7 7 p.

Research output: Contribution to journalArticle

Leukocyte-rich Platelet-rich Plasma injections do not up-modulate intra- articular pro-inflammatory cytokines in the osteoarthritic knee

Mariani, E., Canella, V., Cattini, L., Kon, E., Marcacci, M., Di Matteo, B., Pulsatelli, L. & Filardo, G., Jun 1 2016, In : PLoS One. 11, 6, 13 p., e0156137.

Research output: Contribution to journalArticle

Long-term Results after Hyaluronan-based MACT for the Treatment of Cartilage Lesions of the Patellofemoral Joint

Kon, E., Filardo, G., Gobbi, A., Berruto, M., Andriolo, L., Ferrua, P., Crespiatico, I. & Marcacci, M., Mar 1 2016, In : American Journal of Sports Medicine. 44, 3, p. 602-608 7 p.

Research output: Contribution to journalArticle