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Research Output 2002 2019

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2019

Peripheral localization of the epithelial sodium channel in the apical membrane of bronchial epithelial cells

Musante, I., Scudieri, P., Venturini, A., Guidone, D., Caci, E., Castellani, S., Conese, M. & Galietta, L. J. V., Jun 2019, In : Experimental Physiology. 104, 6, p. 866-875 10 p.

Research output: Contribution to journalArticle

Epithelial Sodium Channels
Epithelial Cells
Tight Junctions
Membranes
Epithelium

Small molecule-facilitated anion transporters in cells for a novel therapeutic approach to cystic fibrosis

Fiore, M., Cossu, C., Capurro, V., Picco, C., Ludovico, A., Mielczarek, M., Carreira-Barral, I., Caci, E., Baroni, D., Quesada, R. & Moran, O., Jun 2019, In : British Journal of Pharmacology. 176, 11, p. 1764-1779 16 p.

Research output: Contribution to journalArticle

Bicarbonates
Cystic Fibrosis
Anions
Chlorides
Iodides

SWATH label-free proteomics for cystic fibrosis research

Braccia, C., Tomati, V., Caci, E., Pedemonte, N. & Armirotti, A., Jul 2019, In : Journal of Cystic Fibrosis. 18, 4, p. 501-506 6 p.

Research output: Contribution to journalArticle

Cystic Fibrosis
Proteomics
Proteome
Research
Proteins

TRPV4 and purinergic receptor signalling pathways are separately linked in airway epithelia to CFTR and TMEM16A chloride channels

Genovese, M., Borrelli, A., Venturini, A., Guidone, D., Caci, E., Viscido, G., Gambardella, G., di Bernardo, D., Scudieri, P. & Galietta, L. J. V., Dec 2019, In : Journal of Physiology. 597, 24, p. 5859-5878 20 p.

Research output: Contribution to journalArticle

Purinergic Receptors
Chloride Channels
Epithelium
Epithelial Cells
Inbred F344 Rats

Two CFTR mutations within codon 970 differently impact on the chloride channel functionality

Amato, F., Scudieri, P., Musante, I., Tomati, V., Caci, E., Comegna, M., Maietta, S., Manzoni, F., Di Lullo, A. M., De Wachter, E., Vanderhelst, E., Terlizzi, V., Braggion, C., Castaldo, G. & Galietta, L. J. V., Jun 2019, In : Human Mutation. 40, 6, p. 742-748 7 p.

Research output: Contribution to journalArticle

Cystic Fibrosis Transmembrane Conductance Regulator
Chloride Channels
Codon
Mutation
Pharmacology
2018

Anion-Transport Mechanism of a Triazole-Bearing Derivative of Prodigiosine: A Candidate for Cystic Fibrosis Therapy

Cossu, C., Fiore, M., Baroni, D., Capurro, V., Caci, E., Garcia-Valverde, M., Quesada, R. & Moran, O., 2018, In : Frontiers in Pharmacology. 9, p. 852

Research output: Contribution to journalArticle

Triazoles
Cystic Fibrosis
Anions
Chlorides
Prodigiosin

High-throughput screening identifies FAU protein as a regulator of mutant cystic fibrosis transmembrane conductance regulator channel

Tomati, V., Pesce, E., Caci, E., Sondo, E., Scudieri, P., Marini, M., Amato, F., Castaldo, G., Ravazzolo, R., Galietta, L. J. V. & Pedemonte, N., Jan 1 2018, In : Journal of Biological Chemistry. 293, 4, p. 1203-1217 15 p.

Research output: Contribution to journalArticle

Cystic Fibrosis Transmembrane Conductance Regulator
Screening
Throughput
Proteins
Cell membranes

Increased expression of ATP12A proton pump in cystic fibrosis airways

Scudieri, P., Musante, I., Caci, E., Venturini, A., Morelli, P., Walter, C., Tosi, D., Palleschi, A., Martin-Vasallo, P., Sermet-Gaudelus, I., Planelles, G., Crambert, G. & Galietta, L. J., Oct 18 2018, In : JCI insight. 3, 20

Research output: Contribution to journalArticle

Proton Pumps
Cystic Fibrosis
Epithelium
Bacterial Infections
Interleukin-4

Increased expression of ATP12A proton pump in cystic fibrosis airways

Scudieri, P., Musante, I., Caci, E., Venturini, A., Morelli, P., Walter, C., Tosi, D., Palleschi, A., Martin-Vasallo, P., Sermet-Gaudelus, I., Planelles, G., Crambert, G. & Galietta, L. J., 2018, In : JCI insight. 3, 20

Research output: Contribution to journalArticle

Increased expression of ATP12A proton pump in cystic fibrosis airways

Scudieri, P., Musante, I., Caci, E., Venturini, A., Morelli, P., Walter, C., Tosi, D., Palleschi, A., Martin-Vasallo, P., Sermet-Gaudelus, I., Planelles, G., Crambert, G. & Galietta, L. J., 2018, In : JCI insight. 3, 20

Research output: Contribution to journalArticle

In vitro Methods for the Development and Analysis of Human Primary Airway Epithelia

Gianotti, A., Delpiano, L. & Caci, E., 2018, In : Frontiers in Pharmacology. 9, p. 1176

Research output: Contribution to journalArticle

Human Development
Epithelium
Ion Transport
Cystic Fibrosis
Cystic Fibrosis Transmembrane Conductance Regulator

Pharmacological Inhibition of the Ubiquitin Ligase RNF5 Rescues F508del-CFTR in Cystic Fibrosis Airway Epithelia

Sondo, E., Falchi, F., Caci, E., Ferrera, L., Giacomini, E., Pesce, E., Tomati, V., Mandrup Bertozzi, S., Goldoni, L., Armirotti, A., Ravazzolo, R., Cavalli, A. & Pedemonte, N., Jul 19 2018, In : Cell Chemical Biology. 25, 7, p. 891-905.e8

Research output: Contribution to journalArticle

Ligases
Ubiquitin
Cystic Fibrosis
Epithelium
Pharmacology

The Autophagy Inhibitor Spautin-1 Antagonizes Rescue of Mutant CFTR Through an Autophagy-Independent and USP13-Mediated Mechanism

Pesce, E., Sondo, E., Ferrera, L., Tomati, V., Caci, E., Scudieri, P., Musante, I., Renda, M., Baatallah, N., Servel, N., Hinzpeter, A., di Bernardo, D., Pedemonte, N. & Galietta, L. J. V., 2018, In : Frontiers in Pharmacology. 9, p. 1464

Research output: Contribution to journalArticle

Autophagy
Cystic Fibrosis
Biological Phenomena
Chloride Channels
Quality Control
2017

Murine Rankl-/- Mesenchymal Stromal Cells Display an Osteogenic Differentiation Defect Improved by a RANKL-Expressing Lentiviral Vector

Schena, F., Menale, C., Caci, E., Diomede, L., Palagano, E., Recordati, C., Sandri, M., Tampieri, A., Bortolomai, I., Capo, V., Pastorino, C., Bertoni, A., Gattorno, M., Martini, A., Villa, A., Traggiai, E. & Sobacchi, C., May 2017, In : Stem Cells. 35, 5, p. 1365-1377 13 p.

Research output: Contribution to journalArticle

Osteopetrosis
Mesenchymal Stromal Cells
Bone Marrow
Bone Diseases
Hematopoietic Stem Cell Transplantation

Murine Rankl-/- Mesenchymal Stromal Cells Display an Osteogenic Differentiation Defect Improved by a RANKL-Expressing Lentiviral Vector

Schena, F., Menale, C., Caci, E., Diomede, L., Palagano, E., Recordati, C., Sandri, M., Tampieri, A., Bortolomai, I., Capo, V., Pastorino, C., Bertoni, A., Gattorno, M., Martini, A., Villa, A., Traggiai, E. & Sobacchi, C., May 2017, In : Stem Cells. 35, 5, p. 1365-1377 13 p.

Research output: Contribution to journalArticle

Osteopetrosis
Mesenchymal Stromal Cells
Bone Marrow
Bone Diseases
Hematopoietic Stem Cell Transplantation
2016

CD4+CD25highCD127- regulatory T-cells in COPD: Smoke and drugs effect

Chiappori, A., Folli, C., Balbi, F., Caci, E., Riccio, A. M., De Ferrari, L., Melioli, G., Braido, F. & Canonica, G. W., Feb 12 2016, (Accepted/In press) In : World Allergy Organization Journal.

Research output: Contribution to journalArticle

Regulatory T-Lymphocytes
Smoke
Chronic Obstructive Pulmonary Disease
Pharmaceutical Preparations
Budesonide

Evaluation of a systems biology approach to identify pharmacological correctors of the mutant CFTR chloride channel

Pesce, E., Gorrieri, G., Sirci, F., Napolitano, F., Carrella, D., Caci, E., Tomati, V., Zegarra Moran, O., Di Bernardo, D. & Galietta, L. J. V., Jul 2016, In : Journal of Cystic Fibrosis. 15, 4, p. 425-35 11 p.

Research output: Contribution to journalArticle

Chloride Channels
Systems Biology
Mometasone Furoate
Pharmacology
Cystic Fibrosis

Goblet Cell Hyperplasia Requires High Bicarbonate Transport to Support Mucin Release

Gorrieri, G., Scudieri, P., Caci, E., Schiavon, M., Tomati, V., Sirci, F., Napolitano, F., Carrella, D., Gianotti, A., Musante, I., Favia, M., Casavola, V., Guerra, L., Rea, F., Ravazzolo, R., Di Bernardo, D. & Galietta, L. J. V., Oct 27 2016, In : Scientific Reports. 6, 36016.

Research output: Contribution to journalArticle

Goblet Cells
Mucins
Bicarbonates
Hyperplasia
Interleukin-4

Pharmacological analysis of epithelial chloride secretion mechanisms in adult murine airways

Gianotti, A., Ferrera, L., Philp, A. R., Caci, E., Zegarra-Moran, O., Galietta, L. J. V. & Flores, C. A., Jun 15 2016, In : European Journal of Pharmacology. 781, p. 100-108 9 p.

Research output: Contribution to journalArticle

Chloride Channels
Chlorides
Pharmacology
Cystic Fibrosis
Calcium Chloride
2015

Evaluation of a systems biology approach to identify pharmacological correctors of the mutant CFTR chloride channel

Pesce, E., Gorrieri, G., Sirci, F., Napolitano, F., Carrella, D., Caci, E., Tomati, V., Zegarra-Moran, O., di Bernardo, D. & Galietta, L. J. V., Jul 14 2015, (Accepted/In press) In : Journal of Cystic Fibrosis.

Research output: Contribution to journalArticle

Chloride Channels
Systems Biology
Mometasone Furoate
Pharmacology
Cystic Fibrosis

Functional analysis of acid-activated Cl- channels: Properties and mechanisms of regulation

Capurro, V., Gianotti, A., Caci, E., Ravazzolo, R., Galietta, L. J. V. & Zegarra-Moran, O., 2015, In : BBA - Biomembranes. Part A, p. 105-114 10 p.

Research output: Contribution to journalArticle

Functional analysis
Chemical activation
Phosphatidylinositol 3-Kinase
Dynamins
Phosphorylation

Genetic Inhibition of the Ubiquitin Ligase Rnf5 Attenuates Phenotypes Associated to F508del Cystic Fibrosis Mutation

Tomati, V., Sondo, E., Armirotti, A., Caci, E., Pesce, E., Marini, M., Gianotti, A., Ju Jeon, Y., Cilli, M., Pistorio, A., Mastracci, L., Ravazzolo, R., Scholte, B., Ronai, Z., Galietta, L. J. V. & Pedemonte, N., Jul 17 2015, In : Scientific Reports. 5, 12138.

Research output: Contribution to journalArticle

Ligases
Ubiquitin
Cystic Fibrosis
Cystic Fibrosis Transmembrane Conductance Regulator
Phenotype

Ion channel and lipid scramblase activity associated with expression of TMEM16F/ANO6 isoforms

Scudieri, P., Caci, E., Venturini, A., Sondo, E., Pianigiani, G., Marchetti, C., Ravazzolo, R., Pagani, F. & Galietta, L. J. V., Sep 1 2015, In : Journal of Physiology. 593, 17, p. 3829-3848 20 p.

Research output: Contribution to journalArticle

Phosphatidylserines
Ion Channels
Phospholipid Transfer Proteins
Protein Isoforms
Lipids

Upregulation of TMEM16A protein in bronchial epithelial cells by bacterial pyocyanin

Caci, E., Scudieri, P., Carlo, E. D., Morelli, P., Bruno, S., De Fino, I., Bragonzi, A., Gianotti, A., Sondo, E., Ferrera, L., Palleschi, A., Santambrogio, L., Ravazzolo, R. & Galietta, L. J. V., Jun 29 2015, In : PLoS One. 10, 6, e0131775.

Research output: Contribution to journalArticle

Pyocyanine
cystic fibrosis
Cystic Fibrosis
epithelial cells
Up-Regulation
2014

Correcting the basic ion transport defects in cystic fibrosis

Caci, E. & Galietta, L. J. V., 2014, In : European Respiratory Monograph. 64, p. 116-128 13 p.

Research output: Contribution to journalArticle

Cystic Fibrosis Transmembrane Conductance Regulator
Ion Transport
Cystic Fibrosis
Mutation
Chloride Channels

Non-canonical translation start sites in the TMEM16A chloride channel

Sondo, E., Scudieri, P., Tomati, V., Caci, E., Mazzone, A., Farrugia, G., Ravazzolo, R. & Galietta, L. J. V., 2014, In : BBA - Biomembranes. 1838, 1 PARTB, p. 89-97 9 p.

Research output: Contribution to journalArticle

Chloride Channels
Epitopes
Initiator Codon
Codon
Calcium Chloride

The TMEM16A chloride channel as an alternative therapeutic target in cystic fibrosis

Sondo, E., Caci, E. & Galietta, L. J. V., 2014, In : International Journal of Biochemistry and Cell Biology. 52, p. 73-76 4 p.

Research output: Contribution to journalArticle

Chloride Channels
Cystic Fibrosis
Cytology
Physiology
Mucins
2013

A novel missense mutation in ANO5/TMEM16E is causative for gnathodiaphyseal dyplasia in a large Italian pedigree

Marconi, C., Binello, P. B., Badiali, G., Caci, E., Cusano, R., Garibaldi, J., Pippucci, T., Merlini, A., Marchetti, C., Rhoden, K. J., Galietta, L. J. V., Lalatta, F., Balbi, P. & Seri, M., Jun 1 2013, In : European Journal of Human Genetics. 21, 6, p. 613-619 7 p.

Research output: Contribution to journalArticle

Missense Mutation
Pedigree
Chloride Channels
Mutation
Untranslated Regions

Epithelial sodium channel silencing as a strategy to correct the airway surface fluid deficit in cystic fibrosis

Gianotti, A., Melani, R., Caci, E., Sondo, E., Ravazzolo, R., Galietta, L. J. V. & Zegarra-Moran, O., Sep 2013, In : American Journal of Respiratory Cell and Molecular Biology. 49, 3, p. 445-452 8 p.

Research output: Contribution to journalArticle

Epithelial Sodium Channels
Cystic Fibrosis Transmembrane Conductance Regulator
Cystic Fibrosis
Fluids
Small Interfering RNA

TMEM16A-TMEM16B chimaeras to investigate the structure-function relationship of calcium-activated chloride channels

Scudieri, P., Sondo, E., Caci, E., Ravazzolo, R. & Galietta, L. J. V., Jun 15 2013, In : Biochemical Journal. 452, 3, p. 443-455 13 p.

Research output: Contribution to journalArticle

Chloride Channels
Proteins
Chemical activation
Kinetics
Amino Acids
2012

Association of TMEM16A chloride channel overexpression with airway goblet cell metaplasia

Scudieri, P., Caci, E., Bruno, S., Ferrera, L., Schiavon, M., Sondo, E., Tomati, V., Gianotti, A., Zegarra-Moran, O., Pedemonte, N., Rea, F., Ravazzolo, R. & Galietta, L. J. V., Dec 2012, In : Journal of Physiology. 590, 23, p. 6141-6155 15 p.

Research output: Contribution to journalArticle

Chloride Channels
Goblet Cells
Metaplasia
Interleukin-4
Epithelial Cells

Cytokines induce tight junction disassembly in airway cells via an EGFR-dependent MAPK/ERK1/2-pathway

Petecchia, L., Sabatini, F., Usai, C., Caci, E., Varesio, L. & Rossi, G. A., Aug 2012, In : Laboratory Investigation. 92, 8, p. 1140-1148 9 p.

Research output: Contribution to journalArticle

MAP Kinase Signaling System
Tight Junctions
Mitogen-Activated Protein Kinase 1
Epidermal Growth Factor Receptor
Cytokines

Salbutamol: How does it enter smooth muscle cells?

Chiappori, A., Folli, C., Riccio, A. M., Caci, E., Descalzi, D., De Ferrari, L., Ingrassia, E., Nicolini, G. & Canonica, G. W., Apr 2012, In : International Journal of Immunopathology and Pharmacology. 25, 2, p. 541-546 6 p.

Research output: Contribution to journalArticle

Albuterol
Smooth Muscle Myocytes
Beclomethasone
Corticosterone
Pharmaceutical Preparations
2011

A minimal isoform of the TMEM16A protein associated with chloride channel activity

Ferrera, L., Scudieri, P., Sondo, E., Caputo, A., Caci, E., Zegarra-Moran, O., Ravazzolo, R. & Galietta, L. J. V., Sep 2011, In : BBA - Biomembranes. 1808, 9, p. 2214-2223 10 p.

Research output: Contribution to journalArticle

Chloride Channels
Protein Isoforms
Anions
Proteins
Amino Acids

Dual activity of aminoarylthiazoles on the trafficking and gating defects of the cystic fibrosis transmembrane conductance regulator chloride channel caused by cystic fibrosis mutations

Pedemonte, N., Tomati, V., Sondo, E., Caci, E., Millo, E., Armirotti, A., Damonte, G., Zegarra-Moran, O. & Galietta, L. J. V., Apr 29 2011, In : Journal of Biological Chemistry. 286, 17, p. 15215-15226 12 p.

Research output: Contribution to journalArticle

Cystic Fibrosis Transmembrane Conductance Regulator
Chloride Channels
Cystic Fibrosis
Defects
Mutation

Rescue of the mutant CFTR chloride channel by pharmacological correctors and low temperature analyzed by gene expression profiling

Sondo, E., Tomati, V., Caci, E., Esposito, A. I., Pfeffer, U., Pedemonte, N. & Galietta, L. J. V., Oct 2011, In : American Journal of Physiology - Cell Physiology. 301, 4

Research output: Contribution to journalArticle

ciclopirox
Aminacrine
Chloride Channels
Gene Expression Profiling
Epithelial Cells
2009

Epithelial sodium channel inhibition in primary human bronchial epithelia by transfected siRNA

Caci, E., Melani, R., Pedemonte, N., Yueksekdag, G., Ravazzolo, R., Rosenecker, J., Galietta, L. J. V. & Zegarra-Moran, O., Feb 1 2009, In : American Journal of Respiratory Cell and Molecular Biology. 40, 2, p. 211-216 6 p.

Research output: Contribution to journalArticle

Epithelial Sodium Channels
Small Interfering RNA
Epithelium
Cystic Fibrosis Transmembrane Conductance Regulator
Fluids

IL-12 can target human lung adenocarcinoma cells and normal bronchial epithelial cells surrounding tumor lesions

Airoldi, I., Di Carlo, E., Cocco, C., Caci, E., Cilli, M., Sorrentino, C., Sozzi, G., Ferrini, S., Rosini, S., Bertolini, G., Truini, M., Grossi, F., Galietta, L. J. V., Ribatti, D. & Pistoia, V., Jul 1 2009, In : PLoS One. 4, 7, e6119.

Research output: Contribution to journalArticle

interleukin-12
Interleukin-12
adenocarcinoma
lesions (animal)
Tumors

Mutation-specific potency and efficacy of cystic fibrosis transmembrane conductance regulator chloride channel potentiators

Caputo, A., Hinzpeter, A., Caci, E., Pedemonte, N., Arous, N., Di Duca, M., Zegarra-Moran, O., Fanen, P. & Galietta, L. J. V., 2009, In : Journal of Pharmacology and Experimental Therapeutics. 330, 3, p. 786-791 6 p.

Research output: Contribution to journalArticle

Cystic Fibrosis Transmembrane Conductance Regulator
Chloride Channels
Mutation
Felodipine
Cystic Fibrosis
2008

Evidence for direct CFTR inhibition by CFTRinh-172 based on Arg347 mutagenesis

Caci, E., Caputo, A., Hinzpeter, A., Arous, N., Fanen, P., Sonawane, N., Verkman, A. S., Ravazzolo, R., Zegarra-Moran, O. & Galietta, L. J. V., Jul 1 2008, In : Biochemical Journal. 413, 1, p. 135-142 8 p.

Research output: Contribution to journalArticle

Cystic Fibrosis Transmembrane Conductance Regulator
Mutagenesis
Amino Acids
Alanine
Basic Amino Acids

TMEM16A, a membrane protein associated with calcium-dependent chloride channel activity

Caputo, A., Caci, E., Ferrera, L., Pedemonte, N., Barsanti, C., Sondo, E., Pfeffer, U., Ravazzolo, R., Zegarra-Moran, O. & Galietta, L. J. V., Oct 24 2008, In : Science. 322, 5901, p. 590-594 5 p.

Research output: Contribution to journalArticle

Calcium Chloride
Chloride Channels
Membrane Proteins
Interleukin-4
Olfactory Perception
2007

Block of CFTR-dependent chloride currents by inhibitors of multidrug resistance-associated proteins

Diena, T., Melani, R., Caci, E., Pedemonte, N., Sondo, E., Zegarra-Moran, O. & Galietta, L. J. V., Apr 10 2007, In : European Journal of Pharmacology. 560, 2-3, p. 127-131 5 p.

Research output: Contribution to journalArticle

Multidrug Resistance-Associated Proteins
Cystic Fibrosis Transmembrane Conductance Regulator
Chlorides
Membrane Proteins
Benzbromarone

Thiocyanate transport in resting and IL-4-stimulated human bronchial epithelial cells: Role of pendrin and anion channels

Pedemonte, N., Caci, E., Sondo, E., Caputo, A., Rhoden, K., Pfeffer, U., Di Candia, M., Bandettini, R., Ravazzolo, R., Zegarra-Moran, O. & Galietta, L. J. V., Apr 15 2007, In : Journal of Immunology. 178, 8, p. 5144-5153 10 p.

Research output: Contribution to journalArticle

Lactoperoxidase
Oxidants
Interleukin-4
Anions
Epithelium
2005

Antihypertensive 1,4-dihydropyridines as correctors of the cystic fibrosis transmembrane conductance regulator channel gating defect caused by cystic fibrosis mutations

Pedemonte, N., Diena, T., Caci, E., Nieddu, E., Mazzei, M., Ravazzolo, R., Zegarra-Moran, O. & Galietta, L. J. V., Dec 2005, In : Molecular Pharmacology. 68, 6, p. 1736-1746 11 p.

Research output: Contribution to journalArticle

Cystic Fibrosis Transmembrane Conductance Regulator
Cystic Fibrosis
Antihypertensive Agents
Mutation
Isradipine

Gelsolin secretion in interleukin-4-treated bronchial epithelia and in asthmatic airways

Candiano, G., Bruschi, M., Pedemonte, N., Caci, E., Liberatori, S., Bini, L., Pellegrini, C., Viganò, M., O'Connor, B. J., Lee, T. H., Galietta, L. J. V. & Zegarra-Moran, O., Nov 1 2005, In : American Journal of Respiratory and Critical Care Medicine. 172, 9, p. 1090-1096 7 p.

Research output: Contribution to journalArticle

Gelsolin
Interleukin-4
Epithelium
Asthma
Epithelial Cells

Small-molecule correctors of defective ΔF508-CFTR cellular processing identified by high-throughput screening

Pedemonte, N., Lukacs, G. L., Du, K., Caci, E., Zegarra-Moran, O., Galietta, L. J. V. & Verkman, A. S., Sep 2005, In : Journal of Clinical Investigation. 115, 9, p. 2564-2571 8 p.

Research output: Contribution to journalArticle

Cystic Fibrosis
Cystic Fibrosis Transmembrane Conductance Regulator
Mutation
Chloride Channels
Temperature
2004

Effect of inflammatory stimuli on airway ion transport.

Galietta, L. J. V., Folli, C., Caci, E., Pedemonte, N., Taddei, A., Ravazzolo, R. & Zegarra-Moran, O., 2004, In : Proc Am Thorac Soc. 1, 1, p. 62-65 4 p.

Research output: Contribution to journalArticle

Ion Transport
Interleukin-4
Epithelial Sodium Channels
Mucociliary Clearance
Fluids and Secretions
2003

2-(Dialkylamino)-4H-1-benzopyran-4-one derivatives modify chloride conductance in CFTR expressing cells

Mazzei, M., Nieddu, E., Folli, C., Caci, E. & Galietta, L. V. J., Sep 1 2003, In : Farmaco. 58, 9, p. 961-970 10 p.

Research output: Contribution to journalArticle

Cystic Fibrosis Transmembrane Conductance Regulator
Chlorides
Apigenin
Iodides
Thyroid Gland

CFTR activation in human bronchial epithelial cells by novel benzoflavone and benzimidazolone compounds

Caci, E., Folli, C., Zegarra-Moran, O., Ma, T., Springsteel, M. F., Sammelson, R. E., Nantz, M. H., Kurth, M. J., Verkman, A. S. & Galietta, L. J. V., Jul 1 2003, In : American Journal of Physiology - Lung Cellular and Molecular Physiology. 285, 1 29-1

Research output: Contribution to journalArticle

Benzoflavones
Epithelial Cells
flavone
Apigenin
Inbred F344 Rats
2002

Correction of G551D-CFTR transport defect in epithelial monolayers by genistein but not by CPX or MPB-07

Zegarra-Moran, O., Romio, L., Folli, C., Caci, E., Becq, F., Vierfond, J. M., Mettey, Y., Cabrini, G., Fanen, P. & Galietta, L. J. V., Oct 2002, In : British Journal of Pharmacology. 137, 4, p. 504-512 9 p.

Research output: Contribution to journalArticle

Cystic Fibrosis Transmembrane Conductance Regulator
Genistein
Epithelium
Thyroid Gland
Epithelial Cells