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Research Output 2018 2020

2020

Real-world outcomes according to treatment strategies in ALK-rearranged non-small-cell lung cancer (NSCLC) patients: an Italian retrospective study

Gobbini, E., Chiari, R., Pizzutillo, P., Bordi, P., Ghilardi, L., Pilotto, S., Osman, G., Cappuzzo, F., Cecere, F., Riccardi, F., Scotti, V., Martelli, O., Borra, G., Maiello, E., Rossi, A., Graziano, P., Gregorc, V., Casartelli, C., Sergi, C., Del Conte, A. & 11 others, Delmonte, A., Bareggi, C., Cortinovis, D., Rizzo, P., Tabbò, F., Rossi, G., Bria, E., Galetta, D., Tiseo, M., Di Maio, M. & Novello, S., 2020, In : Clinical and Translational Oncology. 22, 3, p. 294-301

Research output: Contribution to journalArticle

Non-Small Cell Lung Carcinoma
Retrospective Studies
Therapeutics
crizotinib
anaplastic lymphoma kinase
2019

A multicenter REtrospective observational study of first-line treatment with PERtuzumab, trastuzumab and taxanes for advanced HER2 positive breast cancer patients. RePer Study

Gamucci, T., Pizzuti, L., Natoli, C., Mentuccia, L., Sperduti, I., Barba, M., Sergi, D., Iezzi, L., Maugeri-Saccà, M., Vaccaro, A., Magnolfi, E., Gelibter, A., Barchiesi, G., Magri, V., D’Onofrio, L., Cassano, A., Rossi, E., Botticelli, A., Moscetti, L., Omarini, C. & 29 others, Fabbri, M. A., Scinto, A. F., Corsi, D., Carbognin, L., Mazzotta, M., Bria, E., Foglietta, J., Samaritani, R., Garufi, C., Mariani, L., Barni, S., Mirabelli, R., Sarmiento, R., Graziano, V., Santini, D., Marchetti, P., Tonini, G., Di Lauro, L., Sanguineti, G., Paoletti, G., Tomao, S., De Maria, R., Veltri, E., Paris, I., Giotta, F., Latorre, A., Giordano, A., Ciliberto, G. & Vici, P., Feb 1 2019, In : Cancer Biology and Therapy. 20, 2, p. 192-200 9 p.

Research output: Contribution to journalArticle

Taxoids
Observational Studies
Retrospective Studies
Breast Neoplasms
Maintenance

Characterization of Myeloid-derived Suppressor Cells in a Patient With Lung Adenocarcinoma Undergoing Durvalumab Treatment: A Case Report

Bertelli, G., Trovato, R., Ugel, S., Bria, E., Milella, M., Bronte, V. & Pilotto, S., Jul 2019, In : Clinical Lung Cancer. 20, 4, p. e514-e516

Research output: Contribution to journalArticle

Conjunctival Melanoma: Genetic and Epigenetic Insights of a Distinct Type of Melanoma

Rossi, E., Schinzari, G., Maiorano, B. A., Pagliara, M. M., Di Stefani, A., Bria, E., Peris, K., Blasi, M. A. & Tortora, G., Oct 31 2019, In : International Journal of Molecular Sciences. 20, 21

Research output: Contribution to journalReview article

Neurofibromin 1
HSP90 Heat-Shock Proteins
Telomerase
Phosphatases
Sirolimus

Crizotinib in MET deregulated or ROS1 rearranged pretreated non-small-cell lung cancer (METROS): a phase II, prospective, multicentre, two-arms trial

Landi, L., Chiari, R., Tiseo, M., D'Incà, F., Dazzi, C., Chella, A., Delmonte, A., Bonanno, L., Giannarelli, D., Cortinovis, D. L., De Marinis, F., Borra, G., Morabito, A., Gridelli, C., Galetta, D., Barbieri, F., Grossi, F., Capelletto, E., Minuti, G., Mazzoni, F. & 8 others, Verusio, C., Bria, E., Alì, G., Bruno, R., Proietti, A., Fontanini, G., Crinò, L. & Cappuzzo, F., Dec 15 2019, In : Clin. Cancer Res.. p. 7312-7319 8 p.

Research output: Contribution to journalArticle

Non-Small Cell Lung Carcinoma
Disease-Free Survival
Exons
Mutation
Investigational Therapies

Crizotinib in MET-deregulated or ROS1-rearranged pretreated non–small cell lung cancer (METROS): A phase II, prospective, multicenter, two-arms trial

Landi, L., Chiari, R., Tiseo, M., D'Inca, F., Dazzi, C., Chella, A., Delmonte, A., Bonanno, L., Giannarelli, D., Cortinovis, D. L., de Marinis, F., Borra, G., Morabito, A., Gridelli, C., Galetta, D., Barbieri, F., Grossi, F., Capelletto, E., Minuti, G., Mazzoni, F. & 8 others, Verusio, C., Bria, E., Al, G., Bruno, R., Proietti, A., Fontanini, G., Crino, L. & Cappuzzo, F., 2019, In : Clinical Cancer Research. 25, 24, p. 7312-7319 8 p.

Research output: Contribution to journalArticle

Crizotinib in MET-deregulated or ROS1-rearranged pretreated non–small cell lung cancer (METROS): A phase II, prospective, multicenter, two-arms trial: Clinical Cancer Research

Landi, L., Chiari, R., Tiseo, M., D'Inca, F., Dazzi, C., Chella, A., Delmonte, A., Bonanno, L., Giannarelli, D., Cortinovis, D. L., de Marinis, F., Borra, G., Morabito, A., Gridelli, C., Galetta, D., Barbieri, F., Grossi, F., Capelletto, E., Minuti, G., Mazzoni, F. & 8 others, Verusio, C., Bria, E., Al, G., Bruno, R., Proietti, A., Fontanini, G., Crino, L. & Cappuzzo, F., 2019, In : Clin. Cancer Res.. 25, 24, p. 7312-7319 8 p.

Research output: Contribution to journalArticle

Dabrafenib and Trametinib in BRAF Mutant Metastatic Conjunctival Melanoma

Rossi, E., Maiorano, B. A., Pagliara, M. M., Sammarco, M. G., Dosa, T., Martini, M., Rindi, G., Bria, E., Blasi, M. A., Tortora, G. & Schinzari, G., 2019, In : Frontiers in Oncology. 9, p. 232

Research output: Contribution to journalArticle

Melanoma
Skin
Mutation
Mitogen-Activated Protein Kinase Kinases
dabrafenib

Final results of the SENECA (SEcond line NintEdanib in non-small cell lung CAncer) trial

Capelletto, E., Migliorino, M. R., Morabito, A., Chiari, R., Grossi, F., Tiseo, M., Costanzo, F. D., Delmonte, A., Romano, G., Galetta, D., Scotti, V., Gregorc, V., Pisconti, S., Ceresoli, G. L., Del Conte, A., Ciuffreda, L., Colantonio, I., Bria, E., Ricciardi, S., Manzo, A. & 7 others, Metro, G., Morelli, A. M., Critelli, R., Pacchiana, M. V., Stura, I., Migliaretti, G. & Novello, S., Aug 2019, In : Lung Cancer. 134, p. 210-217 8 p.

Research output: Contribution to journalArticle

docetaxel
Non-Small Cell Lung Carcinoma
Appointments and Schedules
Quality of Life
Recurrence

Final results of the SENECA (SEcond line NintEdanib in non-small cell lung CAncer) trial

Capelletto, E., Migliorino, M. R., Morabito, A., Chiari, R., Grossi, F., Tiseo, M., Costanzo, F. D., Delmonte, A., Romano, G., Galetta, D., Scotti, V., Gregorc, V., Pisconti, S., Ceresoli, G. L., Conte, A. D., Ciuffreda, L., Colantonio, I., Bria, E., Ricciardi, S., Manzo, A. & 7 others, Metro, G., Morelli, A. M., Critelli, R., Pacchiana, M. V., Stura, I., Migliaretti, G. & Novello, S., 2019, In : Lung Cancer. 134, p. 210-217 8 p.

Research output: Contribution to journalArticle

Final results of the SENECA (SEcond line NintEdanib in non-small cell lung CAncer) trial

Capelletto, E., Migliorino, M. R., Morabito, A., Chiari, R., Grossi, F., Tiseo, M., Costanzo, F. D., Delmonte, A., Romano, G., Galetta, D., Scotti, V., Gregorc, V., Pisconti, S., Ceresoli, G. L., Conte, A. D., Ciuffreda, L., Colantonio, I., Bria, E., Ricciardi, S., Manzo, A. & 7 others, Metro, G., Morelli, A. M., Critelli, R., Pacchiana, M. V., Stura, I., Migliaretti, G. & Novello, S., 2019, In : Lung Cancer. 134, p. 210-217 8 p.

Research output: Contribution to journalArticle

docetaxel
Non-Small Cell Lung Carcinoma
Appointments and Schedules
Quality of Life
Recurrence

Final results of the SENECA (SEcond line NintEdanib in non-small cell lung CAncer) trial

Capelletto, E., Migliorino, M. R., Morabito, A., Chiari, R., Grossi, F., Tiseo, M., Costanzo, F. D., Delmonte, A., Romano, G., Galetta, D., Scotti, V., Gregorc, V., Pisconti, S., Ceresoli, G. L., Del Conte, A., Ciuffreda, L., Colantonio, I., Bria, E., Ricciardi, S., Manzo, A. & 7 others, Metro, G., Morelli, A. M., Critelli, R., Pacchiana, M. V., Stura, I., Migliaretti, G. & Novello, S., Aug 2019, In : Lung Cancer. 134, p. 210-217 8 p.

Research output: Contribution to journalArticle

docetaxel
Non-Small Cell Lung Carcinoma
Appointments and Schedules
Quality of Life
Recurrence

Gene Expression Profiling of Lung Atypical Carcinoids and Large Cell Neuroendocrine Carcinomas Identifies Three Transcriptomic Subtypes with Specific Genomic Alterations

Simbolo, M., Barbi, S., Fassan, M., Mafficini, A., Ali, G., Vicentini, C., Sperandio, N., Corbo, V., Rusev, B., Mastracci, L., Grillo, F., Pilotto, S., Pelosi, G., Pelliccioni, S., Lawlor, R. T., Tortora, G., Fontanini, G., Volante, M., Scarpa, A. & Bria, E., Sep 1 2019, In : Journal of Thoracic Oncology. 14, 9, p. 1651-1661 11 p.

Research output: Contribution to journalArticle

Open Access
Neuroendocrine Carcinoma
Large Cell Carcinoma
Carcinoid Tumor
Gene Expression Profiling
Lung
Castration
Prostatic Neoplasms
docetaxel
Therapeutics
Androgens

Immunological Backbone of Uveal Melanoma: Is There a Rationale for Immunotherapy?

Rossi, E., Schinzari, G., Zizzari, I. G., Maiorano, B. A., Pagliara, M. M., Sammarco, M. G., Fiorentino, V., Petrone, G., Cassano, A., Rindi, G., Bria, E., Blasi, M. A., Nuti, M. & Tortora, G., Jul 26 2019, In : Cancers. 11, 8

Research output: Contribution to journalReview article

Immunotherapy
Phase III Clinical Trials
Uveal melanoma
Therapeutics
Estrogen Receptors
Multicenter Studies
Breast Neoplasms
Recurrence
Growth

Impact of 21-Gene Breast Cancer Assay on Treatment Decision for Patients with T1-T3, N0-N1, Estrogen Receptor-Positive/Human Epidermal Growth Receptor 2-Negative Breast Cancer: Final Results of the Prospective Multicenter ROXANE Study

Network, V. O., Dieci, M. V., Guarneri, V., Zustovich, F., Mion, M., Morandi, P., Bria, E., Merlini, L., Bullian, P., Oliani, C., Gori, S., Giarratano, T., Orvieto, E., Griguolo, G., Michieletto, S., Saibene, T., Del Bianco, P., De Salvo, G. L. & Conte, P., Nov 2019, In : Oncologist. 24, 11, p. 1424-1431 8 p.

Research output: Contribution to journalArticle

Estrogen Receptors
Multicenter Studies
Breast Neoplasms
Recurrence
Growth

Lung and Gut Microbiota as Potential Hidden Driver of Immunotherapy Efficacy in Lung Cancer

Carbone, C., Piro, G., Di Noia, V., D'Argento, E., Vita, E., Ferrara, M. G., Pilotto, S., Milella, M., Cammarota, G., Gasbarrini, A., Tortora, G. & Bria, E., 2019, In : Mediators of Inflammation. 2019, p. 7652014

Research output: Contribution to journalReview article

Immunotherapy
Lung Neoplasms
Lung
Microbiota
Neoplasms

Lymph-node ratio predicts survival among the different stages of non-small-cell lung cancer: A multicentre analysis

Chiappetta, M., Leuzzi, G., Sperduti, I., Bria, E., Mucilli, F., Lococo, F., Spaggiari, L., Ratto, G. B., Filosso, P. L. & Facciolo, F., Mar 1 2019, In : European Journal of Cardio-thoracic Surgery. 55, 3, p. 405-412 8 p.

Research output: Contribution to journalArticle

Non-Small Cell Lung Carcinoma
Disease-Free Survival
Lymph Nodes
Survival
Survival Rate

Maintenance with lanreotide in small-cell lung cancer expressing somatostatine receptors: A multicenter, randomized, phase 3 trial

Cancer), I. A. FONICAP. O. N. I. F. A. L., Santo, A., Pilotto, S., Galetta, D., Grossi, F., Fasola, G., Romano, G., Bonanno, L., Bearz, A., Papi, M., Roca, E., Catino, A., Follador, A., Rijavec, E., Genova, C., Petrillo, P., Favaretto, A., Giannone, L., Milella, M., Tortora, G. & 2 others, Giannarelli, D. & Bria, E., Aug 2019, In : Lung Cancer. 134, p. 121-126 6 p.

Research output: Contribution to journalArticle

Small Cell Lung Carcinoma
Maintenance
Disease-Free Survival
Observation
Random Allocation

Maintenance with lanreotide in small-cell lung cancer expressing somatostatine receptors: A multicenter, randomized, phase 3 trial

Italian association FONICAP (Operative National Interdisciplinary Force against Lung Cancer), Aug 2019, In : Lung Cancer. 134, p. 121-126 6 p.

Research output: Contribution to journalArticle

Small Cell Lung Carcinoma
Maintenance
Disease-Free Survival
Observation
Survival

Maintenance with lanreotide in small-cell lung cancer expressing somatostatine receptors: A multicenter, randomized, phase 3 trial

On behalf of the Italian association FONICAP (Operative National Interdisciplinary Force against Lung Cancer), Aug 1 2019, In : Lung Cancer. 134, p. 121-126 6 p.

Research output: Contribution to journalArticle

Small Cell Lung Carcinoma
Maintenance
Disease-Free Survival
Observation
Survival

Maintenance with lanreotide in small-cell lung cancer expressing somatostatine receptors: A multicenter, randomized, phase 3 trial

On behalf of the Italian association FONICAP (Operative National Interdisciplinary Force against Lung Cancer), Santo, A., Pilotto, S., Galetta, D., Grossi, F., Fasola, G., Romano, G., Bonanno, L., Bearz, A., Papi, M., Roca, E., Catino, A., Follador, A., Rijavec, E., Genova, C., Petrillo, P., Favaretto, A., Giannone, L., Milella, M., Tortora, G. & 2 others, Giannarelli, D. & Bria, E., 2019, In : Lung Cancer. 134, p. 121-126 6 p.

Research output: Contribution to journalArticle

Maintenance with lanreotide in small-cell lung cancer expressing somatostatine receptors: A multicenter, randomized, phase 3 trial

Santo, A., Pilotto, S., Galetta, D., Grossi, F., Fasola, G., Romano, G., Bonanno, L., Bearz, A., Papi, M., Roca, E., Catino, A., Follador, A., Rijavec, E., Genova, C., Petrillo, P., Favaretto, A., Giannone, L., Milella, M., Tortora, G., Giannarelli, D. & 2 others, Bria, E. & Cancer), I. A. FONICAP. O. N. I. F. A. L., Aug 2019, In : Lung Cancer. 134, p. 121-126 6 p.

Research output: Contribution to journalArticle

Small Cell Lung Carcinoma
Maintenance
Disease-Free Survival
Observation
Random Allocation

Management of locally advanced non-small cell lung cancer in the modern era: A national Italian survey on diagnosis, treatment and multidisciplinary approach

Bruni, A., Giaj-Levra, N., Ciammella, P., Maragna, V., Ferrari, K., Bonti, V., Grossi, F., Greco, S., Greco, C., Borghetti, P., Franceschini, D., Capelletto, E., Perna, M., Banna, G., Vagge, S., Baldini, E., Bria, E., Botti, A., Tiseo, M., Paci, M. & 6 others, Taraborrelli, M., Poletti, V., Granone, P., Ricardi, U., Novello, S. & Scotti, V., Jan 1 2019, In : PLoS One. 14, 11, e0224027.

Research output: Contribution to journalArticle

Open Access
lung neoplasms
Non-Small Cell Lung Carcinoma
Cells
Chemotherapy
Radiotherapy

Management of locally advanced non-small cell lung cancer in the modern era: A national Italian survey on diagnosis, treatment and multidisciplinary approach

Bruni, A., Giaj-Levra, N., Ciammella, P., Maragna, V., Ferrari, K., Bonti, V., Grossi, F., Greco, S., Greco, C., Borghetti, P., Franceschini, D., Capelletto, E., Perna, M., Banna, G., Vagge, S., Baldini, E., Bria, E., Botti, A., Tiseo, M., Paci, M. & 6 others, Taraborrelli, M., Poletti, V., Granone, P., Ricardi, U., Novello, S. & Scotti, V., 2019, In : PLoS One. 14, 11, e0224027.

Research output: Contribution to journalArticle

Muscle mass, assessed at diagnosis by L3-CT scan as a prognostic marker of clinical outcomes in patients with gastric cancer: A systematic review and meta-analysis

Rinninella, E., Cintoni, M., Raoul, P., Pozzo, C., Strippoli, A., Bria, E., Tortora, G., Gasbarrini, A. & Mele, M. C., Nov 1 2019, In : Clinical Nutrition.

Research output: Contribution to journalArticle

Stomach Neoplasms
Meta-Analysis
Biomarkers
Muscles
Confidence Intervals

Osimertinib beyond disease progression in T790M EGFR-positive NSCLC patients: a multicenter study of clinicians' attitudes

Cortellini, A., Leonetti, A., Catino, A., Pizzutillo, P., Ricciuti, B., De Giglio, A., Chiari, R., Bordi, P., Santini, D., Giusti, R., De Tursi, M., Brocco, D., Zoratto, F., Rastelli, F., Citarella, F., Russano, M., Filetti, M., Marchetti, P., Berardi, R., Torniai, M. & 17 others, Cortinovis, D., Sala, E., Maggioni, C., Follador, A., Macerelli, M., Nigro, O., Tuzi, A., Iacono, D., Migliorino, M. R., Banna, G., Porzio, G., Cannita, K., Ferrara, M. G., Bria, E., Galetta, D., Ficorella, C. & Tiseo, M., Aug 7 2019, In : Clinical and Translational Oncology.

Research output: Contribution to journalArticle

Multicenter Studies
Disease Progression
Therapeutics
osimertinib
Disease-Free Survival

PD-L1 Expression in De Novo Metastatic Castration-sensitive Prostate Cancer

Iacovelli, R., Ciccarese, C., Brunelli, M., Bogina, G., Munari, E., Bimbatti, D., Mosillo, C., Fantinel, E., Bria, E., Martignoni, G. & Tortora, G., Sep 2019, In : Journal of Immunotherapy. 42, 7, p. 269-273 5 p.

Research output: Contribution to journalArticle

Castration
Prostatic Neoplasms
Ligands
Neoplasms
Neoplasm Metastasis

PD-L1 for selecting non-small-cell lung cancer patients for first-line immuno-chemotherapy combination: A systematic review and meta-analysis

Rossi, A., Noia, V. D., Gkountakos, A., D'Argento, E., Sartori, G., Vita, E., Monteverdi, S., Lombardo, F., Iacovelli, R., Carbognin, L., Sperduti, I., Milella, M., Tortora, G., Bria, E. & Pilotto, S., Jan 1 2019, In : Immunotherapy. 11, 10, p. 921-930 10 p.

Research output: Contribution to journalReview article

Combination Drug Therapy
Non-Small Cell Lung Carcinoma
Immunotherapy
Meta-Analysis
Disease-Free Survival

Pembrolizumab as first-line treatment for metastatic uveal melanoma

Rossi, E., Pagliara, M. M., Orteschi, D., Dosa, T., Sammarco, M. G., Caputo, C. G., Petrone, G., Rindi, G., Zollino, M., Blasi, M. A., Cassano, A., Bria, E., Tortora, G. & Schinzari, G., Jul 2019, In : Cancer Immunology and Immunotherapy. 68, 7, p. 1179-1185 7 p.

Research output: Contribution to journalArticle

Disease-Free Survival
Survival
Therapeutics
Uveal melanoma
pembrolizumab
Lung Neoplasms
Electrodes
Lung
Neoplasms
Tomography

Poor efficacy of palbociclib in second-line treatment of metastatic lobular breast cancer in a case series: Use before or never more?

Orlandi, A., Aroldi, F., Garutti, M., Di Dio, C., Garufi, G., Iattoni, E., Palazzo, A., Indellicati, G., Franceschini, G., Cassano, A., Bria, E. & Tortora, G., Dec 31 2019, In : Breast Journal.

Research output: Contribution to journalArticle

PTEN in Colorectal Cancer: Shedding Light on Its Role as Predictor and Target

Salvatore, L., Calegari, M. A., Loupakis, F., Fassan, M., Di Stefano, B., Bensi, M., Bria, E. & Tortora, G., Nov 9 2019, In : Cancers. 11, 11

Research output: Contribution to journalReview article

Phosphoric Monoester Hydrolases
Colorectal Neoplasms
Neoplasms
Precision Medicine
Phosphatidylinositol 3-Kinases

PTEN in Colorectal Cancer: Shedding Light on Its Role as Predictor and Target

Salvatore, L., Calegari, M. A., Loupakis, F., Fassan, M., Di Stefano, B., Bensi, M., Bria, E. & Tortora, G., Nov 9 2019, In : Cancers. 11, 11

Research output: Contribution to journalArticle

Phosphoric Monoester Hydrolases
Colorectal Neoplasms
Neoplasms
Precision Medicine
Phosphatidylinositol 3-Kinases

PTEN in lung cancer: Dealing with the problem, building on new knowledge and turning the game around

Gkountakos, A., Sartori, G., Falcone, I., Piro, G., Ciuffreda, L., Carbone, C., Tortora, G., Scarpa, A., Bria, E., Milella, M., Rosell, R., Corbo, V. & Pilotto, S., Aug 2019, In : Cancers. 11, 8, 1141.

Research output: Contribution to journalReview article

Open Access
Lung Neoplasms
Neoplasms
PTEN Phosphohydrolase
Chromosomes, Human, Pair 10
Tumor Suppressor Genes

PTEN in Lung Cancer: Dealing with the Problem, Building on New Knowledge and Turning the Game Around

Gkountakos, A., Sartori, G., Falcone, I., Piro, G., Ciuffreda, L., Carbone, C., Tortora, G., Scarpa, A., Bria, E., Milella, M., Rosell, R., Corbo, V. & Pilotto, S., Aug 9 2019, In : Cancers. 11, 8

Research output: Contribution to journalReview article

Lung Neoplasms
Neoplasms
PTEN Phosphohydrolase
Chromosomes, Human, Pair 10
Tumor Suppressor Genes

Real-world outcomes according to treatment strategies in ALK-rearranged non-small-cell lung cancer (NSCLC) patients: an Italian retrospective study

Gobbini, E., Chiari, R., Pizzutillo, P., Bordi, P., Ghilardi, L., Pilotto, S., Osman, G., Cappuzzo, F., Cecere, F., Riccardi, F., Scotti, V., Martelli, O., Borra, G., Maiello, E., Rossi, A., Graziano, P., Gregorc, V., Casartelli, C., Sergi, C., Del Conte, A. & 11 others, Delmonte, A., Bareggi, C., Cortinovis, D., Rizzo, P., Tabbò, F., Rossi, G., Bria, E., Galetta, D., Tiseo, M., Di Maio, M. & Novello, S., Oct 19 2019, In : Clinical and Translational Oncology. p. 10.1007/s12094-019-02222-8 8 p.

Research output: Contribution to journalArticle

Non-Small Cell Lung Carcinoma
Retrospective Studies
Therapeutics
crizotinib
anaplastic lymphoma kinase

Relationship between performance status or younger age and osimertinib therapy in T790M-positive NSCLC: Are the available data convincing?

Malapelle, U., Rossi, A. & Bria, E., Jan 1 2019, In : Journal of Thoracic Disease. 11, p. S1837-S1840

Research output: Contribution to journalEditorial

Revising PTEN in the Era of Immunotherapy: New Perspectives for an Old Story

Piro, G., Carbone, C., Carbognin, L., Pilotto, S., Ciccarese, C., Iacovelli, R., Milella, M., Bria, E. & Tortora, G., Oct 10 2019, In : Cancers. 11, 10

Research output: Contribution to journalReview article

Immunotherapy
Tumor Microenvironment
Neoplasms
Immune Evasion
Therapeutics

Second-line therapy for metastatic urothelial carcinoma: Defining the best treatment option among immunotherapy, chemotherapy, and antiangiogenic targeted therapies. A systematic review and meta-analysis

Ciccarese, C., Iacovelli, R., Bria, E., Mosillo, C., Bimbatti, D., Fantinel, E., Bisogno, I., Brunelli, M. & Tortora, G., Feb 2019, In : Seminars in Oncology. 46, 1, p. 65-72 8 p.

Research output: Contribution to journalArticle

Immunotherapy
Meta-Analysis
Carcinoma
Drug Therapy
Survival
Cyclin-Dependent Kinase 4
Cyclin D
Aromatase Inhibitors
Breast Neoplasms
Disease-Free Survival
Castration
Observational Studies
Prostatic Neoplasms
Survival
Hormones

Survival Outcomes From a Cumulative Analysis of Worldwide Observational Studies on Sequential Use of New Agents in Metastatic Castration-Resistant Prostate Cancer

investigators, T. CASTOR. S., Caffo, O., Wissing, M., Bianchini, D., Bergman, A., Thomsen, F. B., Schmid, S., Yu, E. Y., Bournakis, E., Sella, A., Zagonel, V., De Giorgi, U., Tucci, M., Gelderblom, H., Galli, L., Pappagallo, G., Bria, E., Sperduti, I. & Oudard, S., Jan 1 2019, In : Clinical Genitourinary Cancer.

Research output: Contribution to journalArticle

Castration
Observational Studies
Prostatic Neoplasms
Survival
Hormones
2018

Avoiding chemotherapy for advanced nononcogene addicted NSCLC overexpressing PD-L1: Rule or option?

Pilotto, S., Carbognin, L., Rossi, A., Tortora, G. & Bria, E., Jun 1 2018, In : Seminars in Oncology. 45, 3, p. 176-180 5 p.

Research output: Contribution to journalArticle

Drug Therapy
Non-Small Cell Lung Carcinoma
Survival
Combination Drug Therapy
Immunotherapy

Clinical implication of changes in body composition and weight in patients with early-stage and metastatic breast cancer

Trestini, I., Carbognin, L., Monteverdi, S., Zanelli, S., De Toma, A., Bonaiuto, C., Nortilli, R., Fiorio, E., Pilotto, S., Di Maio, M., Gasbarrini, A., Scambia, G., Tortora, G. & Bria, E., Sep 1 2018, In : Critical Reviews in Oncology/Hematology. 129, p. 54-66 13 p.

Research output: Contribution to journalReview article

Body Composition
Body Weight
Breast Neoplasms
Weights and Measures
Precision Medicine

Comparison Between Prognostic Classifications in De Novo Metastatic Hormone Sensitive Prostate Cancer

Iacovelli, R., Ciccarese, C., Mosillo, C., Bimbatti, D., Fantinel, E., Stefani, L., Simbolo, M., Romano, M., Mazzarotto, R., Brunelli, M., Bria, E., Scarpa, A., Lawlor, R. T., Artibani, W. & Tortora, G., Oct 1 2018, In : Targeted Oncology. 13, 5, p. 649-655 7 p.

Research output: Contribution to journalArticle

Prostatic Neoplasms
Hormones
docetaxel
Proportional Hazards Models
Population

Genetic alterations analysis in prognostic stratified groups identified TP53 and ARID1A as poor clinical performance markers in intrahepatic cholangiocarcinoma

Simbolo, M., Vicentini, C., Ruzzenente, A., Brunelli, M., Conci, S., Fassan, M., Mafficini, A., Rusev, B., Corbo, V., Capelli, P., Bria, E., Pedron, S., Turri, G., Lawlor, R. T., Tortora, G., Bassi, C., Guglielmi, A. & Scarpa, A., Dec 1 2018, In : Scientific Reports. 8, 1, 7119.

Research output: Contribution to journalArticle

Cholangiocarcinoma
Biomarkers
Recurrence
Gene Amplification
p53 Genes

Hyperprogressive Disease in Patients with Advanced Non-Small Cell Lung Cancer Treated with PD-1/PD-L1 Inhibitors or with Single-Agent Chemotherapy

Ferrara, R., Mezquita, L., Texier, M., Lahmar, J., Audigier-Valette, C., Tessonnier, L., Mazieres, J., Zalcman, G., Brosseau, S., Le Moulec, S., Leroy, L., Duchemann, B., Lefebvre, C., Veillon, R., Westeel, V., Koscielny, S., Champiat, S., Ferté, C., Planchard, D., Remon, J. & 8 others, Boucher, M. E., Gazzah, A., Adam, J., Bria, E., Tortora, G., Soria, J. C., Besse, B. & Caramella, C., Jan 1 2018, (Accepted/In press) In : JAMA oncology. p. E1-E10

Research output: Contribution to journalArticle

CD274 Antigen
Non-Small Cell Lung Carcinoma
Cell Death
Drug Therapy
Survival

Immunotherapy versus standard of care in metastatic renal cell carcinoma. A systematic review and meta-analysis

Iacovelli, R., Ciccarese, C., Bria, E., Bimbatti, D., Fantinel, E., Mosillo, C., Bisogno, I., Brunelli, M., Tortora, G. & Porta, C., Nov 2018, In : Cancer Treatment Reviews. 70, p. 112-117 6 p.

Research output: Contribution to journalReview article

Standard of Care
Renal Cell Carcinoma
Immunotherapy
Meta-Analysis
PubMed