Erich Piovan

Research output

Research output per year 2002 2020

• 21 Article
• 2 Review article

Research output per year

Research output per year

Search results

• 2020

  Cross-talk between GLI transcription factors and FOXC1 promotes T-cell acute lymphoblastic leukemia dissemination

  Tosello, V., Bongiovanni, D., Liu, J., Pan, Q., Yan, K. K., Saccomani, V., Van Trimpont, M., Pizzi, M., Mazzoni, M., Dei Tos, A. P., Amadori, A., Zanovello, P., Van Vlierberghe, P., Yu, J. & Piovan, E., Jul 30 2020, (E-pub ahead of print) In: Leukemia. 17 p.

  Research output: Contribution to journal › Article › peer-review

  • Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 100%
  • Transcription Factors 56%
  • GANT 61 23%
  • Cortactin 19%
  • Ubiquitination 13%

• Crosstalk between Hedgehog pathway and the glucocorticoid receptor pathway as a basis for combination therapy in T-cell acute lymphoblastic leukemia

  Bongiovanni, D., Tosello, V., Saccomani, V., Dalla Santa, S., Amadori, A., Zanovello, P. & Piovan, E., Oct 15 2020, In: Oncogene. 39, 42, p. 6544-6555 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 100%
  • Glucocorticoid Receptors 84%
  • Dexamethasone 34%
  • GANT 61 34%
  • Acetyltransferases 24%

• miR-22-3p Negatively Affects Tumor Progression in T-Cell Acute Lymphoblastic Leukemia

  Saccomani, V., Grassi, A., Piovan, E., Bongiovanni, D., Di Martino, L., Minuzzo, S., Tosello, V. & Zanovello, P., Jul 18 2020, In: Cells. 9, 7, p. 1-13 13 p., 1726.

  Research output: Contribution to journal › Article › peer-review

  • Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 100%
  • Neoplasms 24%
  • MicroRNAs 21%
  • T-Lymphoid Precursor Cells 11%
  • T-Cell Leukemia 11%
• 2018

  A Novel t(8;14)(q24;q11) Rearranged Human Cell Line as a Model for Mechanistic and Drug Discovery Studies of NOTCH1-Independent Human T-Cell Leukemia

  Tosello, V., Milani, G., Martines, A., Macri, N., Van Loocke, W., Matthijssens, F., Buldini, B., Minuzzo, S., Bongiovanni, D., Schumacher, R. F., Amadori, A., Van Vlierberghe, P. & Piovan, E., Oct 9 2018, In: Cells. 7, 10, 10.3390/ce.

  Research output: Contribution to journal › Article › peer-review

  • T-Cell Leukemia 100%
  • Drug Discovery 75%
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma 72%
  • Mutation 62%
  • Antileukemic Agent 59%

• WT1 loss attenuates the TP53-induced DNA damage response in T-cell acute lymphoblastic leukemia

  Bordin, F., Piovan, E., Masiero, E., Ambesi-Impiombato, A., Minuzzo, S., Bertorelle, R., Sacchetto, V., Pilotto, G., Basso, G., Zanovello, P., Amadori, A. & Tosello, V., Feb 2018, In: Haematologica. 103, 2, p. 266-277 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 100%
  • Wilms Tumor 90%
  • T-Cell Leukemia 77%
  • DNA Damage 66%
  • embelin 33%
• 2016

  Calcineurin and GSK-3 inhibition sensitizes T-cell acute lymphoblastic leukemia cells to apoptosis through X-linked inhibitor of apoptosis protein degradation

  Tosello, V., Bordin, F., Yu, J., Agnusdei, V., Indraccolo, S., Basso, G., Amadori, A. & Piovan, E., Apr 2016, In: Leukemia. 30, 4, p. 812 22 p.

  Research output: Contribution to journal › Article › peer-review

  • X-Linked Inhibitor of Apoptosis Protein 100%
  • Glycogen Synthase Kinase 3 90%
  • Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 88%
  • Calcineurin 83%
  • Proteolysis 62%

• Calcineurin complex isolated from T-cell acute lymphoblastic leukemia (T-ALL) cells identifies new signaling pathways including mTOR/AKT/S6K whose inhibition synergize with Calcineurin inhibition to promote T-ALL cell death

  Tosello, V., Saccomani, V., Yu, J., Bordin, F., Amadori, A. & Piovan, E., 2016, In: Oncotarget. 7, 29, p. 45715-45729 15 p.

  Research output: Contribution to journal › Article › peer-review

  • Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 100%
  • Calcineurin 94%
  • Cell Death 57%
  • Calcineurin Inhibitors 23%
  • Drug Combinations 19%
• 2013

  Direct Reversal of Glucocorticoid Resistance by AKT Inhibition in Acute Lymphoblastic Leukemia

  Piovan, E., Yu, J., Tosello, V., Herranz, D., Ambesi-Impiombato, A., DaSilva, A., Sanchez-Martin, M., Perez-Garcia, A., Rigo, I., Castillo, M., Indraccolo, S., Cross, J., deStanchina, E., Paietta, E., Racevskis, J., Rowe, J., Tallman, M., Basso, G., Meijerink, J., Cordon-Cardo, C. & 2 others, Califano, A. & Ferrando, A., Dec 9 2013, In: Cancer Cell. 24, 6, p. 766-776 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Glucocorticoid Receptor Deficiency 100%
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma 64%
  • Glucocorticoids 60%
  • MK 2206 21%
  • Glucocorticoid Receptors 14%
• 2009

  BCL6 suppression of BCL2 via Miz1 and its disruption in diffuse large B cell lymphoma

  Saito, M., Novak, U., Piovan, E., Basso, K., Sumazin, P., Schneider, C., Crespo, M., Shen, Q., Bhagat, G., Califano, A., Chadburn, A., Pasqualucci, L. & Dalla-Favera, R., Jul 7 2009, In: Proceedings of the National Academy of Sciences of the United States of America. 106, 27, p. 11294-11299 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Germinal Center 100%
  • Lymphoma, Large B-Cell, Diffuse 95%
  • Follicular Lymphoma 51%
  • Proto-Oncogenes 49%
  • Genetic Promoter Regions 40%

• Differential expression of constitutive and inducible proteasome subunits in human monocyte-derived DC differentiated in the presence of IFN-α or IL-4

  Tosello, V., Zamarchi, R., Merlo, A., Gorza, M., Piovan, E., Mandruzzato, S., Bronte, V., Wang, X., Ferrone, S., Amadori, A. & Zanovello, P., 2009, In: European Journal of Immunology. 39, 1, p. 56-66 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Proteasome Endopeptidase Complex 100%
  • LMP-2 protein 89%
  • Interleukin-4 88%
  • tapasin 81%
  • Monocytes 79%
• 2007

  Differential regulation of hypoxia-induced CXCR4 triggering during B-cell development and lymphomagenesis

  Piovan, E., Tosello, V., Indraccolo, S., Masiero, M., Persano, L., Esposito, G., Zamarchi, R., Ponzoni, M., Chieco-Bianchi, L., Dalla-Favera, R. & Amadori, A., Sep 15 2007, In: Cancer Research. 67, 18, p. 8605-8614 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Germinal Center 100%
  • Hypoxia 83%
  • B-Lymphocytes 81%
  • Mitogen-Activated Protein Kinase Phosphatases 32%
  • Dual Specificity Phosphatase 1 31%

• In vivo targeting of human neutralizing antibodies against CD55 and CD59 to lymphoma cells increases the antitumor activity of rituximab

  Macor, P., Tripodo, C., Zorzet, S., Piovan, E., Bossi, F., Marzari, R., Amadori, A. & Tedesco, F., Nov 1 2007, In: Cancer Research. 67, 21, p. 10556-10563 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Rituximab 100%
  • Neutralizing Antibodies 92%
  • Biotin 80%
  • Lymphoma 76%
  • Avidin 45%
• 2006

  CXCL12 does not attract CXCR4+ human metastatic neuroblastoma cells: Clinical implications

  Airoldi, I., Raffaghello, L., Piovan, E., Cocco, C., Carlini, B., Amadori, A., Corrias, M. V. & Pistoia, V., Jan 1 2006, In: Clinical Cancer Research. 12, 1, p. 77-82 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Neuroblastoma 100%
  • Cell Line 29%
  • GTP-Binding Protein Regulators 14%
  • Bone Marrow 14%
  • Chemotaxis 10%

• Interruption of tumor dormancy by a transient angiogenic burst within the tumor microenvironment

  Indraccolo, S., Stievano, L., Minuzzo, S., Tosello, V., Esposito, G., Piovan, E., Zamarchi, R., Chieco-Bianchi, L. & Amadori, A., Mar 14 2006, In: Proceedings of the National Academy of Sciences of the United States of America. 103, 11, p. 4216-4221 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Tumor Microenvironment 100%
  • Angiogenesis Inducing Agents 46%
  • Growth 34%
  • Neoplasms 31%
  • Kaposi's Sarcoma 16%
• 2005

  CD40 activation of B-CLL cells is associated with augmented intracellular levels of CD79b and increased BCR expression in a subset of patients [11]

  Minuzzo, S., Indraccolo, S., Tosello, V., Piovan, E., Cabrelle, E., Trentin, L., Semenzato, G. & Amadori, A., Jun 2005, In: Leukemia. 19, 6, p. 1099-1101 3 p.

  Research output: Contribution to journal › Article › peer-review

• Chemokine receptor expression in EBV-associated lymphoproliferation in hu/SCID mice: Implications for CXCL12/CXCR4 axis in lymphoma generation

  Piovan, E., Tosello, V., Indraccolo, S., Cabrelle, A., Baesso, I., Trentin, L., Zamarchi, R., Tamamura, H., Fujii, N., Semenzato, G., Chieco-Bianchi, L. & Amadori, A., Feb 1 2005, In: Blood. 105, 3, p. 931-939 9 p.

  Research output: Contribution to journal › Article › peer-review

  • SCID Mice 100%
  • Chemokine Receptors 94%
  • Human Herpesvirus 4 83%
  • Lymphoma 70%
  • Intraperitoneal 53%

• Heterogeneous intracellular expression of B-cell receptor components in B-cell chronic lymphocytic leukaemia (B-CLL) cells and effects of CD79b gene transfer on surface immunoglobulin levels in a B-CLL-derived cell line

  Minuzzo, S., Indraccolo, S., Tosello, V., Piovan, E., Cabrelle, A., Trentin, L., Semenzato, G. & Amadori, A., Sep 2005, In: British Journal of Haematology. 130, 6, p. 878-889 12 p.

  Research output: Contribution to journal › Article › peer-review

  • B-Cell Antigen Receptors 100%
  • Cellular Structures 83%
  • B-Cell Chronic Lymphocytic Leukemia 83%
  • B-Lymphocytes 60%
  • Cell Line 46%
• 2004

  C and CX3C chemokines: Cell sources and physiopathological implications

  Stievano, L., Piovan, E. & Amadori, A., 2004, In: Critical Reviews in Immunology. 24, 3, p. 205-228 24 p.

  Research output: Contribution to journal › Article › peer-review

  • CX3C Chemokines 100%
  • C Chemokines 85%
  • Chemokines 51%
  • lymphotactin 46%
  • Chemokine CX3CL1 20%
• 2003

  Tumor outgrowth in peripheral blood mononuclear cell-injected SCID mice is not associated with early Epstein-Barr virus reactivation

  Piovan, E., Bonaldi, L., Indraccolo, S., Tosello, V., Menin, C., Comacchio, F., Chieco-Bianchi, L. & Amadori, A., Aug 1 2003, In: Leukemia. 17, 8, p. 1643-1649 7 p.

  Research output: Contribution to journal › Article › peer-review

  • SCID Mice 100%
  • Human Herpesvirus 4 83%
  • Blood Cells 69%
  • B-Lymphocytes 65%
  • Lymphoma 42%
• 2002

  Alternatively spliced forms of Igα and Igβ prevent B cell receptor expression on the cell surface

  Indraccolo, S., Minuzzo, S., Zamarchi, R., Calderazzo, F., Piovan, E. & Amadori, A., 2002, In: European Journal of Immunology. 32, 6, p. 1530-1540 11 p.

  Research output: Contribution to journal › Article › peer-review

  • B-Cell Antigen Receptors 100%
  • B-Lymphocytes 60%
  • Immunoglobulin M 52%
  • Alternative Splicing 21%
  • HEK293 Cells 21%

• Gene transfer in ovarian cancer cells: A comparison between retroviral and lentiviral vectors

  Indraccolo, S., Habeler, W., Tisato, V., Stievano, L., Piovan, E., Tosello, V., Esposito, G., Wagner, R., Uberla, K., Chieco-Bianchi, L. & Amadori, A., Nov 1 2002, In: Cancer Research. 62, 21, p. 6099-6107 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Ovarian Neoplasms 100%
  • enhanced green fluorescent protein 78%
  • Transgenes 47%
  • Genes 44%
  • Neoplasms 30%