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Fingerprint Dive into the research topics where Ernesto Fedele is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 10 Similar Profiles
Glutamic Acid Medicine & Life Sciences
Synapsins Medicine & Life Sciences
Phosphorylation Chemical Compounds
GTP Phosphohydrolases Medicine & Life Sciences
Amyloid beta-Protein Precursor Medicine & Life Sciences
Cyclic GMP Medicine & Life Sciences
Amyotrophic Lateral Sclerosis Medicine & Life Sciences
Nicotinic Receptors Medicine & Life Sciences

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Research Output 2019 2020

cGMP favors the interaction between APP and BACE1 by inhibiting Rab5 GTPase activity

Caudano, F., Montalto, G., Passalacqua, M., Pronzato, M. A., Fedele, E. & Ricciarelli, R., Dec 1 2020, In : Scientific Reports. 10, 1, 1358.

Research output: Contribution to journalArticle

Open Access
Amyloid beta-Protein Precursor
GTP Phosphohydrolases
Cyclic GMP
Amyloid Precursor Protein Secretases
Neuronal Plasticity

Antagonizing α7 nicotinic receptors with methyllycaconitine (MLA) potentiates receptor activity and memory acquisition

van Goethem, N. P., Paes, D., Puzzo, D., Fedele, E., Rebosio, C., Gulisano, W., Palmeri, A., Wennogle, L. P., Peng, Y., Bertrand, D. & Prickaerts, J., Oct 1 2019, In : Cellular Signalling. 62, 109338.

Research output: Contribution to journalArticle

Open Access
Nicotinic Receptors
Cognition
Nervous System Diseases
Psychiatry
Long-Term Potentiation

Enhanced Function and Overexpression of Metabotropic Glutamate Receptors 1 and 5 in the Spinal Cord of the SOD1G93A Mouse Model of Amyotrophic Lateral Sclerosis during Disease Progression

Bonifacino, T., Rebosio, C., Provenzano, F., Torazza, C., Balbi, M., Milanese, M., Raiteri, L., Usai, C., Fedele, E. & Bonanno, G., Sep 13 2019, In : International Journal of Molecular Sciences. 20, 18

Research output: Contribution to journalArticle

Open Access
spinal cord
glutamates
Amyotrophic Lateral Sclerosis
progressions
mice

Leucine-rich repeat kinase 2 phosphorylation on synapsin I regulates glutamate release at pre-synaptic sites

Marte, A., Russo, I., Rebosio, C., Valente, P., Belluzzi, E., Pischedda, F., Montani, C., Lavarello, C., Petretto, A., Fedele, E., Baldelli, P., Benfenati, F., Piccoli, G., Greggio, E. & Onofri, F., Aug 2019, In : Journal of Neurochemistry. 150, 3, p. 264-281 18 p.

Research output: Contribution to journalArticle

Synapsins
Phosphorylation
Leucine
Glutamic Acid
Phosphotransferases