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Research Output 1997 2019

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2019

Management of rare acquired bleeding disorders

Menegatti, M., Biguzzi, E. & Peyvandi, F., Dec 6 2019, In : Hematology (United States). 2019, 1, p. 80-87 8 p.

Research output: Contribution to journalArticle

Open Access
Autoantibodies
Hemorrhage
Blood Coagulation Factors
Early Diagnosis
Immunosuppressive Agents

Severe acquired von Willebrand syndrome secondary to systemic lupus erythematosus

Stufano, F., Baronciani, L., Biguzzi, E., Cozzi, G., Colpani, P., Chisini, M. & Peyvandi, F., 2019, In : Haemophilia. 25, 1, p. e30-e32

Research output: Contribution to journalArticle

2018

Acquired Von Willebrand syndrome and response to desmopressin

Biguzzi, E., Siboni, S. M. & Peyvandi, F., 2018, In : Haemophilia. 24, 1, p. e25-e28

Research output: Contribution to journalArticle

The ISTH Bleeding Assessment Tool and the risk of future bleeding

Fasulo, M. R., Biguzzi, E., Abbattista, M., Stufano, F., Pagliari, M. T., Mancini, I., Gorski, M. M., Cannavò, A., Corgiolu, M., Peyvandi, F. & Rosendaal, F. R., 2018, In : Journal of Thrombosis and Haemostasis. 16, 1, p. 125-130

Research output: Contribution to journalArticle

Hemorrhage
Confidence Intervals
Incidence
Hemostatics
Tertiary Care Centers
2016

Baseline factor VIII plasma levels and age at first bleeding in patients with severe forms of von Willebrand disease

Siboni, S. M., Biguzzi, E., Caiani, V., Mistretta, C., Bucciarelli, P. & Peyvandi, F., Jul 1 2016, In : Haemophilia. 22, 4, p. 564-569 6 p.

Research output: Contribution to journalArticle

Type 3 Von Willebrand's Disease
Factor VIII
Hemorrhage
von Willebrand Diseases
Age of Onset
2015

Long-term prophylaxis in severe factor VII deficiency

Siboni, S. M., Biguzzi, E., Mistretta, C., Garagiola, I. & Peyvandi, F., Nov 1 2015, In : Haemophilia. 21, 6, p. 812-819 8 p.

Research output: Contribution to journalArticle

Factor VII Deficiency
Hemorrhage
Hemarthrosis
Joint Diseases
Joints

Management of pregnancy in type 2B von Willebrand disease: Case report and literature review

Biguzzi, E., Siboni, S. M., Ossola, M. W., Zaina, B., Migliorini, A. C. & Peyvandi, F., Jan 1 2015, In : Haemophilia. 21, 1, p. e98-e103

Research output: Contribution to journalArticle

Predictors of von willebrand disease diagnosis in individuals with borderline von willebrand factor plasma levels

Bucciarelli, P., Siboni, S. M., Stufano, F., Biguzzi, E., Canciani, M. T., Baronciani, L., Pagliari, M. T., La Marca, S., Mistretta, C., Rosendaal, F. R. & Peyvandi, F., Feb 1 2015, In : Journal of Thrombosis and Haemostasis. 13, 2, p. 228-236 9 p.

Research output: Contribution to journalArticle

von Willebrand Diseases
von Willebrand Factor
Blood Group Antigens
Logistic Models
Confidence Intervals
2014
von Willebrand Factor
Enzyme-Linked Immunosorbent Assay
Antibodies
Autoantibodies
Hemorrhage

Genetic background and risk of postpartum haemorrhage: Results from an Italian cohort of 3219 women

Biguzzi, E., Franchi, F., Acaia, B., Ossola, W., Nava, U., Paraboschi, E. M., Asselta, R. & Peyvandi, F., Nov 1 2014, In : Haemophilia. 20, 6, p. e377-e383

Research output: Contribution to journalArticle

Postpartum Hemorrhage
Thromboplastin
Mothers
Integrin alpha2
Integrin alpha2beta1

Management of orthopaedic surgery in rare bleeding disorders

Siboni, S. M., Biguzzi, E., Pasta, G., Mannucci, P. M., Mistretta, C., Fantini, N. N., Solimeno, L. P. & Peyvandi, F., Sep 1 2014, In : Haemophilia. 20, 5, p. 693-701 9 p.

Research output: Contribution to journalArticle

Orthopedics
Hemostatics
Hemorrhage
Hemostasis
Therapeutics
2013
Lupus Coagulation Inhibitor
Hemostasis
Thrombosis
Healthy Volunteers
Antiphospholipid Syndrome

Normal reference ranges of antithrombin, protein C and protein S: Effect of sex, age and hormonal status

Franchi, F., Biguzzi, E., Martinelli, I., Bucciarelli, P., Palmucci, C., D'Agostino, S. & Peyvandi, F., Aug 2013, In : Thrombosis Research. 132, 2

Research output: Contribution to journalArticle

Antithrombin Proteins
Protein S
Protein C
Reference Values
Menopause

Orthopaedic surgery in patients with von Willebrand disease

Siboni, S. M., Biguzzi, E., Solimeno, L. P., Pasta, G., Mistretta, C., Mannucci, P. M. & Peyvandi, F., 2013, In : Haemophilia. 20, 1, p. 133-140 8 p.

Research output: Contribution to journalArticle

von Willebrand Diseases
Orthopedics
Deamino Arginine Vasopressin
Intravenous Immunoglobulins
Hemorrhage
2012

Elevated prepartum fibrinogen levels are not associated with a reduced risk of postpartum hemorrhage

Peyvandi, F., Biguzzi, E., Franchi, F., Bucciarelli, P., Acaia, B., Zaina, B. & Musallam, K. M., Jul 2012, In : Journal of Thrombosis and Haemostasis. 10, 7, p. 1451-1453 3 p.

Research output: Contribution to journalArticle

Antithrombin Proteins
Protein S
Venous Thromboembolism
Protein C
Protein C Deficiency

Risk factors for postpartum hemorrhage in a cohort of 6011 Italian women

Biguzzi, E., Franchi, F., Ambrogi, F., Ibrahim, B., Bucciarelli, P., Acaia, B., Radaelli, T., Biganzoli, E. & Mannucci, P. M., Apr 2012, In : Thrombosis Research. 129, 4

Research output: Contribution to journalArticle

Postpartum Hemorrhage
Nomograms
Hemoglobins
Obstetric Delivery
Retained Placenta

The JAK2 V617F mutation in patients with cerebral venous thrombosis

Passamonti, S. M., Biguzzi, E., Cazzola, M., Franchi, F., Gianniello, F., Bucciarelli, P., Pietra, D., Mannucci, P. M. & Martinelli, I., Jun 2012, In : Journal of Thrombosis and Haemostasis. 10, 6, p. 998-1003 6 p.

Research output: Contribution to journalArticle

Intracranial Thrombosis
Venous Thrombosis
Mutation
Neoplasms
Thrombophilia
2011

Coagulation testing before epidural analgesia at delivery: Cost analysis

Franchi, F., Ibrahim, B., Rossi, F., Maspero, M. L., Morabito, O., Asti, D., Bucciarelli, P. & Biguzzi, E., Jul 2011, In : Thrombosis Research. 128, 1, p. 18-20 3 p.

Research output: Contribution to journalArticle

Epidural Analgesia
Hematoma
Costs and Cost Analysis
Pregnant Women
Fibrinogen

Standardization of lupus anticoagulant. Feasibility study of a calibration model to minimize between-method variability

Tripodi, A., Chantarangkul, V., Clerici, M., Palmucci, C., Bison, E., Banzato, A., Biguzzi, E. & Pengo, V., Jun 2011, In : Thrombosis Research. 127, 6, p. 589-594 6 p.

Research output: Contribution to journalArticle

Lupus Coagulation Inhibitor
Feasibility Studies
Calibration
Anticoagulants
International Normalized Ratio
2010

Maternal and fetal thrombophilia in intrauterine growth restriction in the presence or absence of maternal hypertensive disease

Pileri, P., Franchi, F., Cetin, I., Mandó, C., Antonazzo, P., Ibrahim, B., Rossi, F. & Biguzzi, E., Sep 2010, In : Reproductive Sciences. 17, 9, p. 844-848 5 p.

Research output: Contribution to journalArticle

Thrombophilia
Mothers
Pregnancy Induced Hypertension
Growth
Pre-Eclampsia
2009

A new chromogenic assay (HemosIL ThromboPath) is sensitive to major prothrombotic risk factors affecting the protein C pathway. Results of a multicenter study

Toulon, P., Smirnov, M., Triscott, M., Safa, O., Biguzzi, E., Bouziane, K. & Tripodi, A., May 2009, In : Thrombosis Research. 124, 1, p. 137-143 7 p.

Research output: Contribution to journalArticle

Protein C
Multicenter Studies
Protein C Deficiency
Lupus Coagulation Inhibitor
Snake Venoms
2007

Association of protein S p.Pro667Pro dimorphism with plasma protein S levels in normal individuals and patients with inherited protein S deficiency

Castaman, G., Biguzzi, E., Razzari, C., Tosetto, A., Fontana, G., Asti, D., Brancaccio, V., Castori, D., Lane, D. A. & Faioni, E. M., 2007, In : Thrombosis Research. 120, 3, p. 421-426 6 p.

Research output: Contribution to journalArticle

Protein S Deficiency
Protein S
Blood Proteins
Genotype
Mutation
Thrombomodulin
Protein C
Liver Diseases
Hepatocellular Carcinoma
Chronic Disease

Interference of factor V Leiden on protein S activity: Evaluation of a new prothrombin time-based assay

Tripodi, A., Asti, D., Chantarangkul, V., Biguzzi, E. & Mannucci, P. M., Sep 2007, In : Blood Coagulation and Fibrinolysis. 18, 6, p. 543-546 4 p.

Research output: Contribution to journalArticle

Protein S
Prothrombin Time
factor V Leiden
2006

c.30IC>T (p.Arg101Cys): A novel mutation in the thrombin-sensitive region of protein S associated with a dysfunctional protein

Franchi, F., Viscardi, Y., Razzari, C., Faioni, E. M., Bonara, P., Biguzzi, E. & Mannucci, P. M., Sep 2006, In : Thrombosis and Haemostasis. 96, 3, p. 381-383 3 p.

Research output: Contribution to journalArticle

Marburg I polymorphism of factor VII-activating protease and risk of venous thromboembolism [1]

Franchi, F., Martinelli, I., Biguzzi, E., Bucciarelli, P. & Mannucci, P. M., Feb 15 2006, In : Blood. 107, 4, p. 1731 1 p.

Research output: Contribution to journalArticle

Polymorphisms of the protein Z-dependent protease inhibitor (ZPI) gene and the risk of venous thromboembolism [6]

Razzari, C., Martinelli, I., Bucciarelli, P., Viscardi, Y. & Biguzzi, E., May 2006, In : Thrombosis and Haemostasis. 95, 5, p. 909-910 2 p.

Research output: Contribution to journalArticle

Protein S binding to phospholipids: Evaluation of eight variants of recombinant human protein S from the PROSIT study [6]

Razzari, C., Franchi, F. & Biguzzi, E., Jan 2006, In : Journal of Thrombosis and Haemostasis. 4, 1, p. 273-274 2 p.

Research output: Contribution to journalArticle

Thrombosis: Annexin V C/T-1 polymorphism and pregnancy complications

Franchi, F., Viscardi, Y., Cetin, I., Bucciarelli, P., Martinelli, I. & Biguzzi, E., Jun 2006, In : Haematologica. 91, 6, p. 864 1 p.

Research output: Contribution to journalArticle

Pregnancy Complications
Annexin A5
Thrombosis
Pregnancy
Genotype
2005

Low levels of protein Z and the risk of venous thromboembolism

Martinelli, I., Razzari, C., Biguzzi, E., Bucciarelli, P. & Mannucci, P. M., Dec 2005, In : Journal of Thrombosis and Haemostasis. 3, 12, p. 2817-2819 3 p.

Research output: Contribution to journalArticle

Molecular diversity and thrombotic risk in protein S deficiency: The PROSIT study

Biguzzi, E., Razzari, C., Lane, D. A., Castaman, G., Cappellari, A., Bucciarelli, P., Fontana, G., Margaglione, M., D'Andrea, G., Simmonds, R. E., Rezende, S. M., Preston, R., Prisco, D., Faioni, E. M., Finazzi, G., Legnani, C., Iannaccaro, F., Rogolino, A., Mori, M., Armani, U. & 10 others, Rossi, E., Brancaccio, V., Papa, M. L., De Caterina, M., Castori, L., Berrettini, M., De Stefano, V., Faillace, F., Barillari, G. & Lippi, G., 2005, In : Human Mutation. 25, 3, p. 259-269 11 p.

Research output: Contribution to journalArticle

Protein S Deficiency
Protein S
Venous Thrombosis
Pulmonary Embolism
Factor Va
2004

A proteomic analysis of changes in prothrombin and plasma proteins associated with the G20210A mutation

Gelfi, C., Viganò, A., Ripamonti, M., Wait, R., Begum, S., Biguzzi, E., Castaman, G. & Faioni, E. M., Jul 2004, In : Proteomics. 4, 7, p. 2151-2159 9 p.

Research output: Contribution to journalArticle

Prothrombin
Proteomics
Blood Proteins
Electrospray ionization
Mutation

Expression of endothelial protein C receptor and thrombomodulin in human coronary atherosclerotic plaques

Merlini, P. A., Rossi, M. L., Faioni, E. M., Franchi, F., Bramucci, E., Lucreziotti, S., Biguzzi, E., Mannucci, P. M. & Ardissino, D., Jan 2004, In : Italian Heart Journal. 5, 1, p. 42-47 6 p.

Research output: Contribution to journalArticle

Atherosclerotic Plaques
Protein C
Thrombomodulin
P-Selectin
E-Selectin

Expression of endothelial protein C receptor and thrombomodulin in the intestinal tissue of patients with inflammatory bowel disease.

Faioni, E. M., Ferrero, S., Fontana, G., Gianelli, U., Ciulla, M. M., Vecchi, M., Saibeni, S., Biguzzi, E., Cordani, N., Franchi, F., Bosari, S. & Cattaneo, M., May 2004, In : Critical Care Medicine. 32, 5 Suppl

Research output: Contribution to journalArticle

Thrombomodulin
Protein C
Inflammatory Bowel Diseases
Diverticulitis
Reverse Transcriptase Polymerase Chain Reaction

Intrauterine growth restriction and genetic predisposition to thrombophilia

Franchi, F., Cetin, I., Todros, T., Antonazzo, P., Nobile De Santis, M. S., Cardaropoli, S., Bucciarelli, P. & Biguzzi, E., Apr 2004, In : Haematologica. 89, 4, p. 444-449 6 p.

Research output: Contribution to journalArticle

Thrombophilia
Genetic Predisposition to Disease
Methylenetetrahydrofolate Reductase (NADPH2)
Umbilicus
Growth
2003

Identification of differentially expressed genes in coronary atherosclerotic plaques from patients with stable or unstable angina by cDNA array analysis

Randi, A. M., Biguzzi, E., Falciani, F., Merlini, P., Blakemore, S., Bramucci, E., Lucreziotti, S., Lennon, M., Faioni, E. M., SsiNo, D. A. & Mannucci, P. M., Apr 2003, In : Journal of Thrombosis and Haemostasis. 1, 4, p. 829-835 7 p.

Research output: Contribution to journalArticle

Stable Angina
Unstable Angina
Atherosclerotic Plaques
Oligonucleotide Array Sequence Analysis
Genes
2002

A rebuttal: Foetal growth restriction in children with prothrombotic risk factors (multiple letters)

Cetin, I., Biguzzi, E., Von Kries, R., Junker, R., Oberle, D., Kosch, A. & Nowak-Göttl, U., 2002, In : Thrombosis and Haemostasis. 87, 5, p. 926-927 2 p.

Research output: Contribution to journalArticle

Mutations in the thrombomodulin gene are rare in patients with severe thrombophilia

Faioni, E. M., Franchi, F., Castaman, G., Biguzzi, E. & Rodeghiero, F., 2002, In : British Journal of Haematology. 118, 2, p. 595-599 5 p.

Research output: Contribution to journalArticle

Thrombomodulin
Thrombophilia
Mutation
Genes
Protein C

Point mutations in the endothelial protein C receptor (EPCR) promoter

Biguzzi, E., Gu, J. M., Merati, G., Esmon, N. L. & Esmon, C. T., 2002, In : Thrombosis and Haemostasis. 87, 6, p. 1085-1086 2 p.

Research output: Contribution to journalArticle

2001

A 23bp insertion in the endothelial protein C receptor (EPCR) gene impairs EPCR function

Biguzzi, E., Merati, G., Liaw, P. C. Y., Bucciarelli, P., Oganesyan, N., Qu, D., Gu, J. M., Fetiveau, R., Esmon, C. T., Mannucci, P. M. & Faioni, E. M., 2001, In : Thrombosis and Haemostasis. 86, 4, p. 945-948 4 p.

Research output: Contribution to journalArticle

Protein C
Genes
Proteins
Insertional Mutagenesis
Venous Thrombosis

Mutations in the thrombomodulin and endothelial protein C receptor genes in women with late fetal loss

Franchi, F., Biguzzi, E., Cetin, I., Facchetti, F., Radaelli, T., Bozzo, M., Pardi, G. & Faioni, E. M., 2001, In : British Journal of Haematology. 114, 3, p. 641-646 6 p.

Research output: Contribution to journalArticle

Thrombomodulin
Protein C
Mutation
Genes
Placental Insufficiency
1999

Splenectomy for idiopathic thrombocytopenic purpura: Comparison of laparoscopic and conventional surgery

Marassi, A., Vignali, A., Zuliani, W., Biguzzi, E., Bergamo, C., Gianotti, L. & Di Carlo, V., Jan 1999, In : Surgical Endoscopy and Other Interventional Techniques. 13, 1, p. 17-20 4 p.

Research output: Contribution to journalArticle

Idiopathic Thrombocytopenic Purpura
Splenectomy
Laparoscopy
Length of Stay
Postoperative Care
1998

The post-thrombotic syndrome in young women: Retrospective evaluation of prognostic factors

Biguzzi, E., Mozzi, E., Alatri, A., Taioli, E., Moia, M. & Mannucci, P. M., Oct 1998, In : Thrombosis and Haemostasis. 80, 4, p. 575-577 3 p.

Research output: Contribution to journalArticle

Venous Thrombosis
Body Mass Index
Compression Stockings
Doppler Color Ultrasonography
Young Syndrome
1997

High prevalence of Helicobacter pylori infection in patients with colonic adenomas and carcinomas

Meucci, G., Tatarella, M., Vecchi, M., Ranzi, M. L., Biguzzi, E., Beccari, G., Clerici, E. & De Franchis, R., Dec 1997, In : Journal of Clinical Gastroenterology. 25, 4, p. 605-607 3 p.

Research output: Contribution to journalArticle

Helicobacter Infections
Helicobacter pylori
Adenoma
Carcinoma
Polyps