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Research Output 1983 2020

2020

Implementing anti-epidermal growth factor receptor (EGFR) therapy in metastatic colorectal cancer: challenges and future perspectives

Martinelli, E., Ciardiello, D., Martini, G., Troiani, T., Cardone, C., Vitiello, P. P., Normanno, N., Rachiglio, A. M., Maiello, E., Latiano, T., De Vita, F. & Ciardiello, F., Jan 2020, In : Annals of Oncology. 31, 1, p. 30-40 11 p.

Research output: Contribution to journalReview article

Open Access
Epidermal Growth Factor Receptor
Colorectal Neoplasms
Therapeutics
Combination Drug Therapy
Monoclonal Antibodies

Intestinal adenosquamous carcinoma with a synchronous skin metastasis: a immunohistochemical and molecular analysis

Parente, P., Covelli, C., Parrella, P., Latiano, T. P., Fiordelisi, F., Pellico, M. T., Maiello, E. & Graziano, P., Feb 1 2020, In : International Journal of Colorectal Disease. 35, 2, p. 337-341 5 p.

Research output: Contribution to journalArticle

Adenosquamous Carcinoma
Neoplasm Metastasis
Skin
Missense Mutation
Catenins

Khorana score and thromboembolic risk in stage II–III colorectal cancer patients: a post hoc analysis from the adjuvant TOSCA trial

Barni, S., Rosati, G., Lonardi, S., Pella, N., Banzi, M., Zampino, M. G., Dotti, K. F., Rimassa, L., Marchetti, P., Maiello, E., Artioli, F., Ferrari, D., Labianca, R., Bidoli, P., Zaniboni, A., Sobrero, A., Iaffaioli, V., De Placido, S., Frassineti, G. L., Ciarlo, A. & 11 others, Buonadonna, A., Silvestris, N., Piazza, E., Pavesi, L., Moroni, M., Clerico, M., Aglietta, M., Giordani, P., Galli, F., Galli, F. & Petrelli, F., Jan 1 2020, In : Therapeutic Advances in Medical Oncology. 12

Research output: Contribution to journalArticle

Open Access
Colorectal Neoplasms
Adjuvant Chemotherapy
Confidence Intervals
Logistic Models
Survival
2019

Aflibercept Plus FOLFIRI for Second-line Treatment of Metastatic Colorectal Cancer: Observations from the Global Aflibercept Safety and Health-Related Quality-of-Life Program (ASQoP)

Riechelmann, R. P., Srimuninnimit, V., Bordonaro, R., Kavan, P., Di Bartolomeo, M., Maiello, E., Cicin, I., García-Alfonso, P., Chau, I., Fedyanin, M. Y., Martos, C. F., Ter-Ovanesov, M., Peeters, M., Ko, Y. J., Yalcin, S., Karthaus, M., Aparicio, J., Heinemann, V., Picard, P., Bury, D. & 2 others, Drea, E. & Sobrero, A., Sep 1 2019, In : Clinical Colorectal Cancer. 18, 3, p. 183-191.e3

Research output: Contribution to journalArticle

Open Access
oxaliplatin
Colorectal Neoplasms
Quality of Life
Safety
Disease Progression

Assessment of Ramucirumab plus paclitaxel as switch maintenance versus continuation of first-line chemotherapy in patients with advanced HER-2 negative gastric or gastroesophageal junction cancers: The ARMANI phase III trial

Di Bartolomeo, M., Niger, M., Morano, F., Corallo, S., Antista, M., Tamberi, S., Lonardi, S., Di Donato, S., Berardi, R., Scartozzi, M., Cardellino, G. G., Di Costanzo, F., Rimassa, L., Luporini, A. G., Longarini, R., Zaniboni, A., Bertolini, A., Tomasello, G., Pinotti, G., Scagliotti, G. & 19 others, Tortora, G., Bonetti, A., Spallanzani, A., Frassineti, G. L., Tassinari, D., Giuliani, F., Cinieri, S., Maiello, E., Verusio, C., Bracarda, S., Catalano, V., Basso, M., Ciuffreda, L., De Vita, F., Parra, H. S., Fornaro, L., Caporale, M., De Braud, F. & Pietrantonio, F., Mar 29 2019, In : BMC Cancer. 19, 1, 283.

Research output: Contribution to journalArticle

Esophagogastric Junction
Paclitaxel
Stomach
Maintenance
Drug Therapy

Assessment of Ramucirumab plus paclitaxel as switch maintenance versus continuation of first-line chemotherapy in patients with advanced HER-2 negative gastric or gastroesophageal junction cancers: The ARMANI phase III trial

Di Bartolomeo, M., Niger, M., Morano, F., Corallo, S., Antista, M., Tamberi, S., Lonardi, S., Di Donato, S., Berardi, R., Scartozzi, M., Cardellino, G. G., Di Costanzo, F., Rimassa, L., Luporini, A. G., Longarini, R., Zaniboni, A., Bertolini, A., Tomasello, G., Pinotti, G., Scagliotti, G. & 19 others, Tortora, G., Bonetti, A., Spallanzani, A., Frassineti, G. L., Tassinari, D., Giuliani, F., Cinieri, S., Maiello, E., Verusio, C., Bracarda, S., Catalano, V., Basso, M., Ciuffreda, L., De Vita, F., Parra, H. S., Fornaro, L., Caporale, M., De Braud, F. & Pietrantonio, F., Mar 29 2019, In : BMC Cancer. 19, 1, 283.

Research output: Contribution to journalArticle

Esophagogastric Junction
Paclitaxel
Stomach
Maintenance
Drug Therapy

Assessment of Ramucirumab plus paclitaxel as switch maintenance versus continuation of first-line chemotherapy in patients with advanced HER-2 negative gastric or gastroesophageal junction cancers: The ARMANI phase III trial

Di Bartolomeo, M., Niger, M., Morano, F., Corallo, S., Antista, M., Tamberi, S., Lonardi, S., Di Donato, S., Berardi, R., Scartozzi, M., Cardellino, G. G., Di Costanzo, F., Rimassa, L., Luporini, A. G., Longarini, R., Zaniboni, A., Bertolini, A., Tomasello, G., Pinotti, G., Scagliotti, G. & 19 others, Tortora, G., Bonetti, A., Spallanzani, A., Frassineti, G. L., Tassinari, D., Giuliani, F., Cinieri, S., Maiello, E., Verusio, C., Bracarda, S., Catalano, V., Basso, M., Ciuffreda, L., De Vita, F., Parra, H. S., Fornaro, L., Caporale, M., De Braud, F. & Pietrantonio, F., Mar 29 2019, In : BMC Cancer. 19, 1, p. 1-9 9 p.

Research output: Contribution to journalArticle

Esophagogastric Junction
Paclitaxel
Stomach
Maintenance
Drug Therapy
Colorectal Neoplasms
Randomized Controlled Trials
GDC-0973
regorafenib
MPDL3280A

Atezolizumab with or without cobimetinib versus regorafenib in previously treated metastatic colorectal cancer (IMblaze370): a multicentre, open-label, phase 3, randomised, controlled trial

Eng, C., Kim, T. W., Bendell, J., Argilés, G., Tebbutt, N. C., Di Bartolomeo, M., Falcone, A., Fakih, M., Kozloff, M., Segal, N. H., Sobrero, A., Yan, Y., Chang, I., Uyei, A., Roberts, L., Ciardiello, F., Ahn, J. B., Asselah, J., Badarinath, S., Baijal, S. & 30 others, Begbie, S., Berry, S., Canon, J. L., Carbone, R. G., Cervantes, A., Cha, Y. J., Chang, K., Chaudhry, A., Chmielowska, E., Cho, S. H., Chu, D., Couture, F., Cultrera, J., Cunningham, D., Van Cutsem, E., Cuyle, P. J., Davies, J., Dowden, S., Dvorkin, M., Ganju, V., Garcia, R. V., Kerr, R., Kim, T. Y., King, K., Kortmansky, J., Lam, K. O., Lee, J., Lee, A. S., Lesperance, B. & Maiello, E., 2019, In : The Lancet Oncology. 20, 6, p. 849-861 13 p.

Research output: Contribution to journalArticle

Diagnostic and prognostic value of B4GALT1 hypermethylation and its clinical significance as a novel circulating cell-free DNA biomarker in colorectal cancer

Picardo, F., Romanelli, A., Muinelo-Romay, L., Mazza, T., Fusilli, C., Parrella, P., Barbazán, J., Lopez-López, R., Barbano, R., De Robertis, M., Taffon, C., Bordoni, V., Agrati, C., Costantini, M., Ricci, F., Graziano, P., Maiello, E., Muscarella, L. A., Fazio, V. M. & Poeta, M. L., 2019, In : Cancers. 11, 10

Research output: Contribution to journalArticle

Diagnostic and prognostic value of B4GALT1 hypermethylation and its clinical significance as a novel circulating cell-free DNA biomarker in colorectal cancer

Picardo, F., Romanelli, A., Muinelo-Romay, L., Mazza, T., Fusilli, C., Parrella, P., Barbazán, J., Lopez-López, R., Barbano, R., De Robertis, M., Taffon, C., Bordoni, V., Agrati, C., Costantini, M., Ricci, F., Graziano, P., Maiello, E., Muscarella, L. A., Fazio, V. M. & Poeta, M. L., Oct 2019, In : Cancers. 11, 10, p. 1-16 16 p., 1598.

Research output: Contribution to journalArticle

Open Access
Colorectal Neoplasms
Biomarkers
DNA
Methylation
Neoplasm Metastasis

DPYD*6 plays an important role in fluoropyrimidine toxicity in addition to DPYD*2A and c.2846A>T: a comprehensive analysis in 1254 patients

Del Re, M., Cinieri, S., Michelucci, A., Salvadori, S., Loupakis, F., Schirripa, M., Cremolini, C., Crucitta, S., Barbara, C., Di Leo, A., Latiano, T. P., Pietrantonio, F., Di Donato, S., Simi, P., Passardi, A., De Braud, F., Altavilla, G., Zamagni, C., Bordonaro, R., Butera, A. & 6 others, Maiello, E., Pinto, C., Falcone, A., Mazzotti, V., Morganti, R. & Danesi, R., Jan 1 2019, In : Pharmacogenomics Journal.

Research output: Contribution to journalArticle

Dihydrouracil Dehydrogenase (NADP)
Drug-Related Side Effects and Adverse Reactions
Neutropenia
Real-Time Polymerase Chain Reaction

DPYD*6 plays an important role in fluoropyrimidine toxicity in addition to DPYD*2A and c.2846A>T: a comprehensive analysis in 1254 patients

Del Re, M., Cinieri, S., Michelucci, A., Salvadori, S., Loupakis, F., Schirripa, M., Cremolini, C., Crucitta, S., Barbara, C., Di Leo, A., Latiano, T. P., Pietrantonio, F., Di Donato, S., Simi, P., Passardi, A., De Braud, F., Altavilla, G., Zamagni, C., Bordonaro, R., Butera, A. & 6 others, Maiello, E., Pinto, C., Falcone, A., Mazzotti, V., Morganti, R. & Danesi, R., Dec 2019, In : Pharmacogenomics Journal. 19, 6, p. 556-563 8 p.

Research output: Contribution to journalArticle

Dihydrouracil Dehydrogenase (NADP)
Drug-Related Side Effects and Adverse Reactions
Neutropenia
Real-Time Polymerase Chain Reaction

DPYD*6 plays an important role in fluoropyrimidine toxicity in addition to DPYD*2A and c.2846A>T: a comprehensive analysis in 1254 patients

Del Re, M., Cinieri, S., Michelucci, A., Salvadori, S., Loupakis, F., Schirripa, M., Cremolini, C., Crucitta, S., Barbara, C., Di Leo, A., Latiano, T. P., Pietrantonio, F., Di Donato, S., Simi, P., Passardi, A., De Braud, F., Altavilla, G., Zamagni, C., Bordonaro, R., Butera, A. & 6 others, Maiello, E., Pinto, C., Falcone, A., Mazzotti, V., Morganti, R. & Danesi, R., Dec 2019, In : Pharmacogenomics Journal. 19, 6, p. 556-563 8 p.

Research output: Contribution to journalArticle

Dihydrouracil Dehydrogenase (NADP)
Drug-Related Side Effects and Adverse Reactions
Neutropenia
Real-Time Polymerase Chain Reaction

Effects of KEAP1 Silencing on the Regulation of NRF2 Activity in Neuroendocrine Lung Tumors

Sparaneo, A., Fabrizio, F. P., la Torre, A., Graziano, P., Di Maio, M., Fontana, A., Bisceglia, M., Rossi, A., Pizzolitto, S., De Maglio, G., Tancredi, A., Grimaldi, F., Balsamo, T., Centra, F., Manzorra, M. C., Trombetta, D., Pantalone, A., Bonfitto, A., Maiello, E., Fazio, V. M. & 1 others, Muscarella, L. A., May 23 2019, In : International Journal of Molecular Sciences. 20, 10

Research output: Contribution to journalArticle

Open Access
Neuroendocrine Tumors
Carcinoid Tumor
lungs
Tumors
Methylation

EphA2 is a predictive biomarker of resistance and a potential therapeutic target for improving antiepidermal growth factor receptor therapy in colorectal cancer

Martini, G., Cardone, C., Vitiello, P. P., Belli, V., Napolitano, S., Troiani, T., Ciardiello, D., Della Corte, C. M., Morgillo, F., Matrone, N., Sforza, V., Papaccio, G., Desiderio, V., Paul, M. C., Moreno-Viedma, V., Normanno, N., Rachiglio, A. M., Tirino, V., Maiello, E., Latiano, T. P. & 5 others, Rizzi, D., Signoriello, G., Sibilia, M., Ciardiello, F. & Martinelli, E., 2019, In : Molecular Cancer Therapeutics. 18, 4, p. 845-855 11 p.

Research output: Contribution to journalArticle

Genomic profiling of KRAS/NRAS/BRAF/PIK3CA wild-type metastatic colorectal cancer patients reveals novel mutations in genes potentially associated with resistance to anti-EGFR agents

Rachiglio, A. M., Lambiase, M., Fenizia, F., Roma, C., Cardone, C., Iannaccone, A., De Luca, A., Carotenuto, M., Frezzetti, D., Martinelli, E., Maiello, E., Ciardiello, F. & Normanno, N., Jun 1 2019, In : Cancers. 11, 6, 859.

Research output: Contribution to journalArticle

Open Access
Epidermal Growth Factor Receptor
Colorectal Neoplasms
Mutation
Genes
Nucleotides

Germline BRCA2 K3326X and CHEK2 I157T mutations increase risk for sporadic pancreatic ductal adenocarcinoma

Obazee, O., Archibugi, L., Andriulli, A., Soucek, P., Małecka-Panas, E., Ivanauskas, A., Johnson, T., Gazouli, M., Pausch, T., Lawlor, R. T., Cavestro, G. M., Milanetto, A. C., Di Leo, M., Pasquali, C., Hegyi, P., Szentesi, A., Radu, C. E., Gheorghe, C., Theodoropoulos, G. E., Bergmann, F. & 41 others, Brenner, H., Vodickova, L., Katzke, V., Campa, D., Strobel, O., Kaiser, J., Pezzilli, R., Federici, F., Mohelnikova-Duchonova, B., Boggi, U., Lemstrova, R., Johansen, J. S., Bojesen, S. E., Chen, I., Jensen, B. V., Capurso, G., Pazienza, V., Dervenis, C., Sperti, C., Mambrini, A., Hackert, T., Kaaks, R., Basso, D., Talar-Wojnarowska, R., Maiello, E., Izbicki, J. R., Cuk, K., Saum, K. U., Cantore, M., Kupcinskas, J., Palmieri, O., Delle Fave, G., Landi, S., Salvia, R., Fogar, P., Vashist, Y. K., Scarpa, A., Vodicka, P., Tjaden, C., Iskierka-Jazdzewska, E. & Canzian, F., Jan 1 2019, In : International Journal of Cancer.

Research output: Contribution to journalArticle

Adenocarcinoma
Mutation
Confidence Intervals
Pancreatic Diseases
Inborn Genetic Diseases

Hsa-miR-210-3p expression in breast cancer and its putative association with worse outcome in patients treated with Docetaxel

Pasculli, B., Barbano, R., Rendina, M., Fontana, A., Copetti, M., Mazza, T., Valori, V. M., Morritti, M., Maiello, E., Graziano, P., Murgo, R., Fazio, V. M., Esteller, M. & Parrella, P., Dec 1 2019, In : Scientific Reports. 9, 1, 14913.

Research output: Contribution to journalArticle

docetaxel
Area Under Curve
Breast Neoplasms
MicroRNAs
ROC Curve

Impact of circulating tumor DNA mutant allele fraction on prognosis in RAS-mutant metastatic colorectal cancer

Elez, E., Chianese, C., Sanz-García, E., Martinelli, E., Noguerido, A., Mancuso, F. M., Caratù, G., Matito, J., Grasselli, J., Cardone, C., Esposito Abate, R., Martini, G., Santos, C., Macarulla, T., Argilés, G., Capdevila, J., Garcia, A., Mulet, N., Maiello, E., Normanno, N. & 5 others, Jones, F., Tabernero, J., Ciardello, F., Salazar, R. & Vivancos, A., Jan 1 2019, In : Molecular Oncology.

Research output: Contribution to journalArticle

Open Access
Colorectal Neoplasms
Alleles
DNA
Disease-Free Survival
Neoplasms

Impact of Metformin Use and Diabetic Status During Adjuvant Fluoropyrimidine-Oxaliplatin Chemotherapy on the Outcome of Patients with Resected Colon Cancer: A TOSCA Study Subanalysis

Investigators, TOSCA. T. O. S. C. A., Vernieri, C., Galli, F., Ferrari, L., Marchetti, P., Lonardi, S., Maiello, E., Iaffaioli, R. V., Zampino, M. G., Zaniboni, A., De Placido, S., Banzi, M., Damiani, A., Ferrari, D., Rosati, G., Labianca, R. F., Bidoli, P., Frassineti, G. L., Nicolini, M., Pavesi, L. & 20 others, Tronconi, M. C., Buonadonna, A., Ferrario, S., Re, G. L., Adamo, V., Tamburini, E., Clerico, M., Giordani, P., Leonardi, F., Barni, S., Ciarlo, A., Cavanna, L., Gori, S., Cinieri, S., Faedi, M., Aglietta, M., Antista, M., Dotti, K. F., Galli, F. & Di Bartolomeo, M., Mar 2019, In : Oncologist. 24, 3, p. 385-393 9 p.

Research output: Contribution to journalArticle

oxaliplatin
Metformin
Colonic Neoplasms
Drug Therapy
Survival

Impact of Metformin Use and Diabetic Status During Adjuvant Fluoropyrimidine-Oxaliplatin Chemotherapy on the Outcome of Patients with Resected Colon Cancer: A TOSCA Study Subanalysis

TOSCA (Three or Six Colon Adjuvant) Investigators, Mar 2019, In : The oncologist. 24, 3, p. 385-393 9 p.

Research output: Contribution to journalArticle

oxaliplatin
Metformin
Colonic Neoplasms
Drug Therapy
Survival

Impact of Metformin Use and Diabetic Status During Adjuvant Fluoropyrimidine-Oxaliplatin Chemotherapy on the Outcome of Patients with Resected Colon Cancer: A TOSCA Study Subanalysis

Vernieri, C., Galli, F., Ferrari, L., Marchetti, P., Lonardi, S., Maiello, E., Iaffaioli, R. V., Zampino, M. G., Zaniboni, A., De Placido, S., Banzi, M., Damiani, A., Ferrari, D., Rosati, G., Labianca, R. F., Bidoli, P., Frassineti, G. L., Nicolini, M., Pavesi, L., Tronconi, M. C. & 20 others, Buonadonna, A., Ferrario, S., Re, G. L., Adamo, V., Tamburini, E., Clerico, M., Giordani, P., Leonardi, F., Barni, S., Ciarlo, A., Cavanna, L., Gori, S., Cinieri, S., Faedi, M., Aglietta, M., Antista, M., Dotti, K. F., Galli, F., Di Bartolomeo, M. & Investigators, TOSCA. T. O. S. C. A., Mar 2019, In : The oncologist. 24, 3, p. 385-393 9 p.

Research output: Contribution to journalArticle

oxaliplatin
Metformin
Colonic Neoplasms
Drug Therapy
Survival

Impact of Metformin Use and Diabetic Status During Adjuvant Fluoropyrimidine-Oxaliplatin Chemotherapy on the Outcome of Patients with Resected Colon Cancer: A TOSCA Study Subanalysis

Vernieri, C., Galli, F., Ferrari, L., Marchetti, P., Lonardi, S., Maiello, E., Iaffaioli, R. V., Zampino, M. G., Zaniboni, A., De Placido, S., Banzi, M., Damiani, A., Ferrari, D., Rosati, G., Labianca, R. F., Bidoli, P., Frassineti, G. L., Nicolini, M., Pavesi, L., Tronconi, M. C. & 18 others, Buonadonna, A., Ferrario, S., Re, G. L., Adamo, V., Tamburini, E., Clerico, M., Giordani, P., Leonardi, F., Barni, S., Ciarlo, A., Cavanna, L., Gori, S., Cinieri, S., Faedi, M., Aglietta, M., Antista, M., Dotti, K. F. & Di Bartolomeo, M., 2019, In : Oncologist. 24, 3, p. 385-393 9 p.

Research output: Contribution to journalArticle

Impact of Metformin Use and Diabetic Status During Adjuvant Fluoropyrimidine-Oxaliplatin Chemotherapy on the Outcome of Patients with Resected Colon Cancer: A TOSCA Study Subanalysis.

Vernieri, C., Galli, F., Ferrari, L., Marchetti, P., Lonardi, S., Maiello, E., Iaffaioli, R. V., Zampino, M. G., Zaniboni, A., De Placido, S., Banzi, M., Damiani, A., Ferrari, D., Rosati, G., Labianca, R. F., Bidoli, P., Frassineti, G. L., Nicolini, M., Pavesi, L., Tronconi, M. C. & 20 others, Buonadonna, A., Ferrario, S., Re, G. L., Adamo, V., Tamburini, E., Clerico, M., Giordani, P., Leonardi, F., Barni, S., Ciarlo, A., Cavanna, L., Gori, S., Cinieri, S., Faedi, M., Aglietta, M., Antista, M., Dotti, K. F., Galli, F., Di Bartolomeo, M. & Investigators, TOSCA. T. O. S. C. A., Mar 1 2019, In : The oncologist. 24, p. 385-393 9 p.

Research output: Contribution to journalArticle

Open Access
methylation
Methylation
cultured cells
genes
lungs

Prevalence, characteristics, and treatment of fatigue in oncological cancer patients in Italy: a cross-sectional study of the Italian Network for Supportive Care in Cancer (NICSO)

Roila, F., Fumi, G., Ruggeri, B., Antonuzzo, A., Ripamonti, C., Fatigoni, S., Cavanna, L., Gori, S., Fabi, A., Marzano, N., Graiff, C., De Sanctis, V., Mirabile, A., Serpentini, S., Bocci, C., Pino, M. S., Cilenti, G., Verusio, C., Ballatori, E., Sbrana, A. & 40 others, Musettini, G., Farnesi, A., Spina, F., Matteucci, P., Bossi, P., Minenza, E., Di Nunzio, C., Orlandi, E., Biasini, C., Inno, A., Turazza, M., Marchetti, F., Pellegrini, D., Gasparro, S., Alesini, D., De Feudis, R., Gasparre, T., Altieri, M., Cretella, E., Marabese, A., Valeriani, M., Scaringi, C., Artale, S., Barbarini, L., Capovilla, E., Tessarin, S., Ivaldi, G. B., Meaglia, I., Maiello, E., Parati, C., Cinieri, S., Coltelli, L., Ribecco, A. S., Romagnoli, E., Ardizzoia, A., Tralongo, P., Falzetta, A., Bandieri, E., Danova, M. & Oncologia), O. B. O. NICSO. N. I. P. L. C. D. S. I., 2019, In : Supportive Care in Cancer. 27, 3, p. 1041-1047 7 p.

Research output: Contribution to journalArticle

Prevalence, characteristics, and treatment of fatigue in oncological cancer patients in Italy: a cross-sectional study of the Italian Network for Supportive Care in Cancer (NICSO)

Roila, F., Fumi, G., Ruggeri, B., Antonuzzo, A., Ripamonti, C., Fatigoni, S., Cavanna, L., Gori, S., Fabi, A., Marzano, N., Graiff, C., De Sanctis, V., Mirabile, A., Serpentini, S., Bocci, C., Pino, M. S., Cilenti, G., Verusio, C., Ballatori, E., Sbrana, A. & 30 others, Musettini, G., Farnesi, A., Spina, F., Matteucci, P., Bossi, P., Minenza, E., Di Nunzio, C., Orlandi, E., Biasini, C., Inno, A., Turazza, M., Marchetti, F., Pellegrini, D., Gasparro, S., Alesini, D., De Feudis, R., Gasparre, T., Altieri, M., Cretella, E., Marabese, A., Valeriani, M., Scaringi, C., Artale, S., Barbarini, L., Capovilla, E., Tessarin, S., Ivaldi, G. B., Meaglia, I., Maiello, E. & Parati, C., 2019, In : Supportive Care in Cancer. 27, 3, p. 1041-1047 7 p.

Research output: Contribution to journalArticle

Real-world outcomes according to treatment strategies in ALK-rearranged non-small-cell lung cancer (NSCLC) patients: an Italian retrospective study

Gobbini, E., Chiari, R., Pizzutillo, P., Bordi, P., Ghilardi, L., Pilotto, S., Osman, G., Cappuzzo, F., Cecere, F., Riccardi, F., Scotti, V., Martelli, O., Borra, G., Maiello, E., Rossi, A., Graziano, P., Gregorc, V., Casartelli, C., Sergi, C., Del Conte, A. & 11 others, Delmonte, A., Bareggi, C., Cortinovis, D., Rizzo, P., Tabbò, F., Rossi, G., Bria, E., Galetta, D., Tiseo, M., Di Maio, M. & Novello, S., Jan 1 2019, (Accepted/In press) In : Clinical and Translational Oncology.

Research output: Contribution to journalArticle

Non-Small Cell Lung Carcinoma
Retrospective Studies
Therapeutics
crizotinib
anaplastic lymphoma kinase

Real-world outcomes according to treatment strategies in ALK-rearranged non-small-cell lung cancer (NSCLC) patients: an Italian retrospective study

Gobbini, E., Chiari, R., Pizzutillo, P., Bordi, P., Ghilardi, L., Pilotto, S., Osman, G., Cappuzzo, F., Cecere, F., Riccardi, F., Scotti, V., Martelli, O., Borra, G., Maiello, E., Rossi, A., Graziano, P., Gregorc, V., Casartelli, C., Sergi, C., Del Conte, A. & 11 others, Delmonte, A., Bareggi, C., Cortinovis, D., Rizzo, P., Tabbò, F., Rossi, G., Bria, E., Galetta, D., Tiseo, M., Di Maio, M. & Novello, S., Oct 19 2019, In : Clinical and Translational Oncology. p. 10.1007/s12094-019-02222-8 8 p.

Research output: Contribution to journalArticle

Non-Small Cell Lung Carcinoma
Retrospective Studies
Therapeutics
crizotinib
anaplastic lymphoma kinase

The Italian Rare Pancreatic Exocrine Cancer Initiative

Brunetti, O., Luchini, C., Argentiero, A., Tommasi, S., Mangia, A., Aprile, G., Marchetti, P., Vasile, E., Casadei Gardini, A., Scartozzi, M., Barni, S., Delfanti, S., De Vita, F., Di Costanzo, F., Milella, M., Cella, C. A., Berardi, R., Cataldo, I., Santini, D., Doglioni, C. & 9 others, Maiello, E., Lawlor, R. T., Mazzaferro, V., Lonardi, S., Giuliante, F., Brandi, G., Scarpa, A., Cascinu, S. & Silvestris, N., Jan 1 2019, In : Tumori.

Research output: Contribution to journalArticle

Pancreatic Neoplasms
Carcinoma
Acinar Cell Carcinoma
Signet Ring Cell Carcinoma
Adenosquamous Carcinoma

The Italian Rare Pancreatic Exocrine Cancer Initiative

Brunetti, O., Luchini, C., Argentiero, A., Tommasi, S., Mangia, A., Aprile, G., Marchetti, P., Vasile, E., Casadei Gardini, A., Scartozzi, M., Barni, S., Delfanti, S., De Vita, F., Di Costanzo, F., Milella, M., Cella, C. A., Berardi, R., Cataldo, I., Santini, D., Doglioni, C. & 9 others, Maiello, E., Lawlor, R. T., Mazzaferro, V., Lonardi, S., Giuliante, F., Brandi, G., Scarpa, A., Cascinu, S. & Silvestris, N., Jan 1 2019, In : Tumori.

Research output: Contribution to journalArticle

Pancreatic Neoplasms
Carcinoma
Acinar Cell Carcinoma
Signet Ring Cell Carcinoma
Adenosquamous Carcinoma
2018
exemestane
letrozole
Tamoxifen
Aromatase Inhibitors
Breast Neoplasms

Adjuvant anastrozole versus exemestane versus letrozole, upfront or after 2 years of tamoxifen, in endocrine-sensitive breast cancer (FATA-GIM3): a randomised, phase 3 trial

De Placido, S., Gallo, C., De Laurentiis, M., Bisagni, G., Arpino, G., Sarobba, M. G., Riccardi, F., Russo, A., Del Mastro, L., Cogoni, A. A., Cognetti, F., Gori, S., Foglietta, J., Frassoldati, A., Amoroso, D., Laudadio, L., Moscetti, L., Montemurro, F., Verusio, C., Bernardo, A. & 209 others, Lorusso, V., Gravina, A., Moretti, G., Lauria, R., Lai, A., Mocerino, C., Rizzo, S., Nuzzo, F., Carlini, P., Perrone, F., Accurso, A., Agostara, B., Aieta, M., Alabiso, O., Alicicco, M. G., Amadori, D., Amaducci, L., Amiconi, G., Antuzzi, G., Ardine, M., Ardizzoia, A., Aversa, C., Badalamenti, G., Barni, S., Basurto, C., Berardi, R., Bergamasco, C., Bidoli, P., Bighin, C., Biondi, E., Bisagni, G., Boni, C., Borgonovo, K., Botta, M., Bravi, S., Bruzzi, P., Buono, G., Butera, A., Caldara, A., Candeloro, G., Cappelletti, C., Cardalesi, C., Carfora, E., Cariello, A., Carrozza, F., Cartenì, G., Caruso, M., Casadei, V., Casanova, C., Castori, L., Cavanna, L., Cavazzini, G., Cazzaniga, M., Chilelli, M., Chiodini, P., Chiorrini, S., Ciardiello, F., Ciccarese, M., Cinieri, S., Clerico, M., Coccaro, M., Comande, M., Corbo, C., Cortino, G., Cusenza, S., Daniele, G., D'arco, A. M., D'auria, G., Dazzi, C., De Angelis, C., de Braud, F., De Feo, G., De Matteis, A., De Tursi, M., Di Blasio, A., di Lucca, G., Di Lullo, L., Di Rella, F., Di Renzo, G., Di Stefano, P., Di Stefano, A., Diana, A., Donati, S., Fabbri, A., Fabi, A., Faedi, M., Farina, G., Farris, A., Febbraro, A., Fedele, P., Federico, P., Ferraù, F., Ferretti, G., Ferro, A., Floriani, I., Forcignanò, R., Forciniti, S., Forestieri, V., Fornari, G., Frisinghelli, M., Fusco, V., Gallizzi, G., Galvano, A., Gambardella, A., Gambi, A., Gebbia, V., Gervasi, E., Ghilardi, M., Giacobino, A., Giardina, G., Giotta, F., Giraudi, S., Giuliano, M., Grassadonia, A., Grasso, D., Grosso, F., Guizzaro, L., Incoronato, P., Incorvaia, L., Iodice, G., La Verde, N., Labonia, V., Landi, G., Latorre, A., Leonardi, V., Levaggi, A., Limite, G., Lina Bascialla, L., Livi, L., Maiello, E., Mandelli, D., Marcon, I., Menon, D., Montedoro, M., Moraca, L., Moretti, A., Morritti, M. G., Morselli, P., Mura, A., Mura, S., Musacchio, M., Muzio, A., Natale, D., Natoli, C., Nigro, C., Nisticò, C., Nuzzo, A., Orditura, M., Orlando, L., Pacilio, C., Palumbo, G., Palumbo, R., Pasini, F., Paterno, E., Pazzola, A., Pelliccioni, S., Pensabene, M., Perroni, D., Pesenti Gritti, A., Petrelli, F., Piccirillo, M. C., Pinotti, G., Pogliani, C., Poli, D., Prader, S., Recchia, F., Rizzi, D., Romano, C., Rossello, R., Rossini, C., Salvucci, G., Sanna, V., Santini, A., Saracchini, S., Savastano, C., Scambia, G., Schettini, F., Schiavone, P., Schirone, A., Seles, E., Signoriello, S., Signoriello, G., Silva, R. R., Silvestri, A., Simeon, V., Spagnoletti, I., Tamberi, S., Teragni, C., Thalmann, V., Thomas, R., Thomas, G., Tienghi, A., Tinari, N., Tinessa, V., Tomei, F., Tonini, G., Torri, V., Traficante, D., Tudini, M., Turazza, M., Vignoli, R., Vitale, M. G., Zacchia, A., Zagarese, P., Zanni, A., Zavallone, L., Zavettieri, M., Zoboli, A. & Investigators, GIM., 2018, In : The Lancet Oncology. 19, 4, p. 474-485 12 p.

Research output: Contribution to journalArticle

Aflibercept Plus FOLFIRI in the Real-life Setting: Safety and Quality of Life Data From the Italian Patient Cohort of the Aflibercept Safety and Quality-of-Life Program Study

Pastorino, A., Di Bartolomeo, M., Maiello, E., Iaffaioli, V., Ciuffreda, L., Fasola, G., Di Costanzo, F., Frassineti, G. L., Marchetti, P., Antoniotti, C., Leone, F., Zaniboni, A., Aprile, G., Zilocchi, C., Sobrero, A. & Bordonaro, R., 2018, In : Clinical Colorectal Cancer. 17, 3, p. e457-e470

Research output: Contribution to journalArticle

Aflibercept Plus FOLFIRI in the Real-life Setting: Safety and Quality of Life Data From the Italian Patient Cohort of the Aflibercept Safety and Quality-of-Life Program Study

Pastorino, A., Di Bartolomeo, M., Maiello, E., Iaffaioli, V., Ciuffreda, L., Fasola, G., Di Costanzo, F., Frassineti, G. L., Marchetti, P., Antoniotti, C., Leone, F., Zaniboni, A., Aprile, G., Zilocchi, C., Sobrero, A. & Bordonaro, R., 2018, In : Clinical Colorectal Cancer. 17, 3, p. e457-e470

Research output: Contribution to journalArticle

gemcitabine
Paclitaxel
Pancreatic Neoplasms
Cost-Benefit Analysis
Albumins
gemcitabine
Paclitaxel
Pancreatic Neoplasms
Cost-Benefit Analysis
Albumins

Crosstalk between the tumor microenvironment and immune system in pancreatic ductal adenocarcinoma: Potential targets for new therapeutic approaches

Parente, P., Parcesepe, P., Covelli, C., Olivieri, N., Remo, A., Pancione, M., Latiano, T. P., Graziano, P., Maiello, E. & Giordano, G., Jan 1 2018, In : Gastroenterology Research and Practice. 2018, 7530619.

Research output: Contribution to journalReview article

Open Access
Tumor Microenvironment
Immune System
Adenocarcinoma
gemcitabine
Cellular Microenvironment

Droplet digital PCR quantification of miR-1290 as a circulating biomarker for pancreatic cancer

Tavano, F., Gioffreda, D., Valvano, M. R., Palmieri, O., Tardio, M., Latiano, T. P., Piepoli, A., Maiello, E., Pirozzi, F. & Andriulli, A., Dec 1 2018, In : Scientific Reports. 8, 1, 16389.

Research output: Contribution to journalArticle

Pancreatic Neoplasms
Biomarkers
Polymerase Chain Reaction
Area Under Curve
MicroRNAs

FOLFOX or CAPOX in stage II to III colon cancer: Efficacy results of the italian three or six colon adjuvant trial

on behalf of the TOSCA Investigators, May 20 2018, In : Journal of Clinical Oncology. 36, 15, p. 1478-1485 8 p.

Research output: Contribution to journalArticle

oxaliplatin
Colonic Neoplasms
Colon
Recurrence
Leucovorin
oxaliplatin
Colonic Neoplasms
Colon
Recurrence
Leucovorin

FOLFOX or CAPOX in stage II to III colon cancer: Efficacy Results of the Italian Three or Six Colon Adjuvant Trial

Investigators, O. B. O. T. TOSCA., Sobrero, A., Lonardi, S., Rosati, G., Di Bartolomeo, M., Ronzoni, M., Pella, N., Scartozzi, M., Banzi, M., Zampino, M. G., Pasini, F., Marchetti, P., Cantore, M., Zaniboni, A., Rimassa, L., Ciuffreda, L., Ferrari, D., Zagonel, V., Maiello, E., Barni, S. & 2 others, Rulli, E. & Labianca, R., May 20 2018, In : Journal of Clinical Oncology. 36, 15, p. 1478-1485 8 p.

Research output: Contribution to journalArticle

oxaliplatin
Colonic Neoplasms
Colon
Recurrence
Leucovorin

FOLFOX or CAPOX in stage II to III colon cancer: Efficacy results of the italian three or six colon adjuvant trial

Sobrero, A., Lonardi, S., Rosati, G., Di Bartolomeo, M., Ronzoni, M., Pella, N., Scartozzi, M., Banzi, M., Zampino, M. G., Pasini, F., Marchetti, P., Cantore, M., Zaniboni, A., Rimassa, L., Ciuffreda, L., Ferrari, D., Zagonel, V., Maiello, E., Barni, S., Rulli, E. & 1 others, Labianca, R., 2018, In : Journal of Clinical Oncology. 36, 15, p. 1478-1485 8 p.

Research output: Contribution to journalArticle

oxaliplatin
Colonic Neoplasms
Colon
Recurrence
Leucovorin

FOLFOX or CAPOX in stage II to III colon cancer: Efficacy results of the italian three or six colon adjuvant trial

Sobrero, A., Lonardi, S., Rosati, G., Di Bartolomeo, M., Ronzoni, M., Pella, N., Scartozzi, M., Banzi, M., Zampino, M. G., Pasini, F., Marchetti, P., Cantore, M., Zaniboni, A., Rimassa, L., Ciuffreda, L., Ferrari, D., Zagonel, V., Maiello, E., Barni, S., Rulli, E. & 1 others, Labianca, R., 2018, In : Journal of Clinical Oncology. 36, 15, p. 1478-1485 8 p.

Research output: Contribution to journalArticle

FOLFOX or CAPOX in Stage II to III Colon Cancer: Efficacy Results of the Italian Three or Six Colon Adjuvant Trial

Investigators, TOSCA., Sobrero, A., Lonardi, S., Rosati, G., Di Bartolomeo, M., Ronzoni, M., Pella, N., Scartozzi, M., Banzi, M., Zampino, M. G., Pasini, F., Marchetti, P., Cantore, M., Zaniboni, A., Rimassa, L., Ciuffreda, L., Ferrari, D., Zagonel, V., Maiello, E., Barni, S. & 2 others, Rulli, E. & Labianca, R., May 20 2018, In : Journal of Clinical Oncology. 36, 15, p. 1478-1485 8 p.

Research output: Contribution to journalArticle

oxaliplatin
Colonic Neoplasms
Colon
Recurrence
Leucovorin

Frequent NRG1 fusions in caucasian pulmonary mucinous adenocarcinoma predicted by Phospho-ErbB3 expression

Trombetta, D., Graziano, P., Scarpa, A., Sparaneo, A., Rossi, G., Rossi, A., Di Maio, M., Antonello, D., Mafficini, A., Fabrizio, F. P., Manzorra, M. C., Balsamo, T., Centra, F., Simbolo, M., Pantalone, A., Notarangelo, M., Parente, P., Dimitri, M. C. L., Bonfitto, A., Fiordelisi, F. & 6 others, Storlazzi, C. T., L'Abbate, A., Taurchini, M., Maiello, E., Fazio, V. M. & Muscarella, L. A., Jan 1 2018, In : Oncotarget. 9, 11, p. 9661-9671 11 p.

Research output: Contribution to journalArticle

Mucinous Adenocarcinoma
Fluorescence In Situ Hybridization
RNA Sequence Analysis
erbB-1 Genes
Chi-Square Distribution

Phase III study with FOLFIRI + cetuximab versus FOLFIRI + cetuximab followed by cetuximab alone in RAS and BRAF WT mCRC

Pinto, C., Normanno, N., Orlandi, A., Fenizia, F., Damato, A., Maiello, E., Tamburini, E., Di Costanzo, F., Tonini, G., Bilancia, D., Corsi, D., Pisconti, S., Ferrau, F., Gori, S., Daniele, B., Zaniboni, A., Soto Parra, H., Frassineti, G. L. P., Iaffaioli, R. V., Cassata, A. & 4 others, Zampino, M. G., Repetto, L., Calegari, M. A. & Barone, C., 2018, In : Future Oncology. 14, 14, p. 1339-1346 8 p.

Research output: Contribution to journalArticle

Phase III study with FOLFIRI + cetuximab versus FOLFIRI + cetuximab followed by cetuximab alone in RAS and BRAF WT mCRC

Pinto, C., Normanno, N., Orlandi, A., Fenizia, F., Damato, A., Maiello, E., Tamburini, E., Di Costanzo, F., Tonini, G., Bilancia, D., Corsi, D., Pisconti, S., Ferrau, F., Gori, S., Daniele, B., Zaniboni, A., Soto Parra, H., Frassinetti, G. L., Iaffaioli, R. V., Cassata, A. & 4 others, Zampino, M. G., Repetto, L., Calegari, M. A. & Barone, C., 2018, In : Future Oncology. 14, 14, p. 1339-1346 8 p.

Research output: Contribution to journalArticle

Phase III study with FOLFIRI + cetuximab versus FOLFIRI + cetuximab followed by cetuximab alone in RAS and BRAF WT mCRC

Pinto, C., Normanno, N., Orlandi, A., Fenizia, F., Damato, A., Maiello, E., Tamburini, E., Di Costanzo, F., Tonini, G., Bilancia, D., Corsi, D., Pisconti, S., Ferrau, F., Gori, S., Daniele, B., Zaniboni, A., Soto Parra, H., Frassinetti, G. L., Iaffaioli, R. V., Cassata, A. & 4 others, Zampino, M. G., Repetto, L., Calegari, M. A. & Barone, C., 2018, In : Future Oncology. 14, 14, p. 1339-1346 8 p.

Research output: Contribution to journalArticle

Colorectal Neoplasms
Therapeutics
Anti-Idiotypic Antibodies
Quality of Life
Medicine