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Research Output 1999 2019

2019

Exosomes From Astrocyte Processes: Signaling to Neurons

Venturini, A., Passalacqua, M., Pelassa, S., Pastorino, F., Tedesco, M., Cortese, K., Gagliani, M. C., Leo, G., Maura, G., Guidolin, D., Agnati, L. F., Marcoli, M. & Cervetto, C., 2019, In : Frontiers in Pharmacology. 10, p. 1452

Research output: Contribution to journalArticle

Exosomes
Astrocytes
Neurons
Neuroprotective Agents
Central Nervous System

Extracts from Cell Suspension Cultures of Strawberry (Fragaria x ananassa Duch): Cytotoxic Effects on Human Cancer Cells

Lucioli, S., Pastorino, F., Nota, P., Ballan, G., Frattarelli, A., Fabbri, A., Forni, C. & Caboni, E., May 4 2019, In : Molecules. 24, 9

Research output: Contribution to journalArticle

Fragaria
Cell culture
Tumors
Suspensions
Cell Culture Techniques

Increased myocardial 18 F-FDG uptake as a marker of Doxorubicin-induced oxidative stress

Bauckneht, M., Pastorino, F., Castellani, P., Cossu, V., Orengo, A. M., Piccioli, P., Emionite, L., Capitanio, S., Yosifov, N., Bruno, S., Lazzarini, E., Ponzoni, M., Ameri, P., Rubartelli, A., Ravera, S., Morbelli, S., Sambuceti, G. & Marini, C., Jan 1 2019, In : Journal of Nuclear Cardiology.

Research output: Contribution to journalArticle

Doxorubicin
Oxidative Stress
Neuroblastoma
Glucose
Troponin I

Microfragmented human fat tissue is a natural scaffold for drug delivery: Potential application in cancer chemotherapy

Alessandri, G., Coccè, V., Pastorino, F., Paroni, R., Dei Cas, M., Restelli, F., Pollo, B., Gatti, L., Tremolada, C., Berenzi, A., Parati, E., Brini, A. T., Bondiolotti, G., Ponzoni, M. & Pessina, A., May 28 2019, In : Journal of Controlled Release. 302, p. 2-18 17 p.

Research output: Contribution to journalArticle

Fats
Drug Therapy
Paclitaxel
Pharmaceutical Preparations
Adipose Tissue

Microfragmented human fat tissue is a natural scaffold for drug delivery: Potential application in cancer chemotherapy

Alessandri, G., Coccè, V., Pastorino, F., Paroni, R., Dei Cas, M., Restelli, F., Pollo, B., Gatti, L., Tremolada, C., Berenzi, A., Parati, E., Brini, A. T., Bondiolotti, G., Ponzoni, M. & Pessina, A., 2019, In : Journal of Controlled Release. 302, p. 2-18 17 p.

Research output: Contribution to journalArticle

Overcoming Biological Barriers in Neuroblastoma Therapy: The Vascular Targeting Approach with Liposomal Drug Nanocarriers

Pastorino, F., Brignole, C., Di Paolo, D., Perri, P., Curnis, F., Corti, A. & Ponzoni, M., Mar 2019, In : Small. 15, 10, p. e1804591

Research output: Contribution to journalReview article

Neuroblastoma
Blood Vessels
Tumors
Pharmaceutical Preparations
Neoplasms

Preclinical evaluation of the first intravenous small molecule MDM2 antagonist alone and in combination with temozolomide in neuroblastoma

Chen, L., Pastorino, F., Berry, P., Bonner, J., Kirk, C., Wood, K. M., Thomas, H. D., Zhao, Y., Daga, A., Veal, G. J., Lunec, J., Newell, D. R., Ponzoni, M. & Tweddle, D. A., Jun 15 2019, In : International Journal of Cancer. 144, 12, p. 3146-3159 14 p.

Research output: Contribution to journalArticle

Open Access
temozolomide
Neuroblastoma
Prodrugs
Liquid Chromatography
Mass Spectrometry

Preclinical evaluation of the first intravenous small molecule MDM2 antagonist alone and in combination with temozolomide in neuroblastoma

Chen, L., Pastorino, F., Berry, P., Bonner, J., Kirk, C., Wood, K. M., Thomas, H. D., Zhao, Y., Daga, A., Veal, G. J., Lunec, J., Newell, D. R., Ponzoni, M. & Tweddle, D. A., 2019, In : International Journal of Cancer. 144, 12, p. 3146-3159 14 p.

Research output: Contribution to journalArticle

Spatiotemporal Regulation of Tumor Angiogenesis by Circulating Chromogranin A Cleavage and Neuropilin-1 Engagement

Dallatomasina, A., Gasparri, A. M., Colombo, B., Sacchi, A., Bianco, M., Daniele, T., Esposito, A., Pastorino, F., Ponzoni, M., Marcucci, F., Curnis, F. & Corti, A., Apr 15 2019, In : Cancer Research. 79, 8, p. 1925-1937 13 p.

Research output: Contribution to journalArticle

Neuropilin-1
Chromogranin A
Neoplasms
Disease Progression
Antibodies
2018

Enhancement of Tumor Homing by Chemotherapy-Loaded Nanoparticles

Ponzoni, M., Curnis, F., Brignole, C., Bruno, S., Guarnieri, D., Sitia, L., Marotta, R., Sacchi, A., Bauckneht, M., Buschiazzo, A., Rossi, A., Di Paolo, D., Perri, P., Gori, A., Sementa, A. R., Emionite, L., Cilli, M., Tamma, R., Ribatti, D., Pompa, P. P. & 4 others, Marini, C., Sambuceti, G., Corti, A. & Pastorino, F., Nov 2018, In : Small. 14, 45, p. e1802886

Research output: Contribution to journalArticle

Chemotherapy
Nanoparticles
Peptides
Tumors
Tissue

Enhancement of Tumor Homing by Chemotherapy-Loaded Nanoparticles

Ponzoni, M., Curnis, F., Brignole, C., Bruno, S., Guarnieri, D., Sitia, L., Marotta, R., Sacchi, A., Bauckneht, M., Buschiazzo, A., Rossi, A., Di Paolo, D., Perri, P., Gori, A., Sementa, A. R., Emionite, L., Cilli, M., Tamma, R., Ribatti, D., Pompa, P. P. & 4 others, Marini, C., Sambuceti, G., Corti, A. & Pastorino, F., 2018, In : Small. 14, 45, 1802886.

Research output: Contribution to journalArticle

Chemotherapy
Nanoparticles
Neuroblastoma
Tumors
Drug Therapy
macrophages
Macrophages
cancer
Neoplasms
Tissue
2017

Doxorubicin effect on myocardial metabolism as a prerequisite for subsequent development of cardiac toxicity: A translational 18F-FDG PET/CT observation

Bauckneht, M., Ferrarazzo, G., Fiz, F., Morbelli, S., Sarocchi, M., Pastorino, F., Ghidella, A., Pomposelli, E., Miglino, M., Ameri, P., Emionite, L., Ticconi, F., Arboscello, E., Buschiazzo, A., Massimelli, E. A., Fiordoro, S., Borra, A., Cossu, V., Bozzano, A., Ibatici, A. & 6 others, Ponzoni, M., Spallarossa, P., Gallamini, A., Bruzzi, P., Sambuceti, G. & Marini, C., Oct 1 2017, In : Journal of Nuclear Medicine. 58, 10, p. 1638-1645 8 p.

Research output: Contribution to journalArticle

Fluorodeoxyglucose F18
Doxorubicin
Observation
Hodgkin Disease
Glucose

Doxorubicin Effect on Myocardial Metabolism as a Prerequisite for Subsequent Development of Cardiac Toxicity: A Translational 18F-FDG PET/CT Observation

Bauckneht, M., Ferrarazzo, G., Fiz, F., Morbelli, S., Sarocchi, M., Pastorino, F., Ghidella, A., Pomposelli, E., Miglino, M., Ameri, P., Emionite, L., Ticconi, F., Arboscello, E., Buschiazzo, A., Massimelli, E. A., Fiordoro, S., Borra, A., Cossu, V., Bozzano, A., Ibatici, A. & 6 others, Ponzoni, M., Spallarossa, P., Gallamini, A., Bruzzi, P., Sambuceti, G. & Marini, C., Oct 2017, In : Journal of Nuclear Medicine. 58, 10, p. 1638-1645 8 p.

Research output: Contribution to journalArticle

Fluorodeoxyglucose F18
Doxorubicin
Observation
Hodgkin Disease
Glucose

Glycine N-methylation in NGR-Tagged Nanocarriers Prevents Isoaspartate formation and Integrin Binding without Impairing CD13 Recognition and Tumor Homing

Corti, A., Gasparri, A. M., Ghitti, M., Sacchi, A., Sudati, F., Fiocchi, M., Buttiglione, V., Perani, L., Gori, A., Valtorta, S., Moresco, R. M., Pastorino, F., Ponzoni, M., Musco, G. & Curnis, F., Sep 26 2017, In : Advanced Functional Materials. 27, 36

Research output: Contribution to journalArticle

Isoaspartic Acid
homing
methylation
Methylation
glycine

Glycine N-Methylation in NGR-Tagged Nanocarriers Prevents Isoaspartate Formation and Integrin Binding without Impairing CD13 Recognition and Tumor Homing

Corti, A., Gasparri, AM., Ghitti, M., Sacchi, A., Sudati, F., Fiocchi, M., Buttiglione, V., Perani, L., Gori, A., Valtorta, S., Moresco, RM., Pastorino, F., Ponzoni, M., Musco, G. & Curnis, F., 2017, In : Advanced Functional Materials. 27, 36, 1701245.

Research output: Contribution to journalArticle

Isoaspartic Acid
homing
methylation
Methylation
glycine
Galectins
Neuroblastoma
Galactose
Screening
Association reactions
2016

A novel liposomal Clodronate depletes tumor-associated macrophages in primary and metastatic melanoma: Anti-angiogenic and anti-tumor effects

Piaggio, F., Kondylis, V., Pastorino, F., Di Paolo, D., Perri, P., Cossu, I., Schorn, F., Marinaccio, C., Murgia, D., Daga, A., Raggi, F., Loi, M., Emionite, L., Ognio, E., Pasparakis, M., Ribatti, D., Ponzoni, M. & Brignole, C., Feb 10 2016, In : Journal of Controlled Release. 223, p. 165-177 13 p.

Research output: Contribution to journalArticle

Clodronic Acid
Melanoma
Macrophages
Neoplasms
Lung

A novel liposomal Clodronate depletes tumor-associated macrophages in primary and metastatic melanoma: Anti-angiogenic and anti-tumor effects

Piaggio, F., Kondylis, V., Pastorino, F., Di Paolo, D., Perri, P., Cossu, I., Schorn, F., Marinaccio, C., Murgia, D., Daga, A., Raggi, F., Loi, M., Emionite, L., Ognio, E., Pasparakis, M., Ribatti, D., Ponzoni, M. & Brignole, C., Feb 10 2016, In : Journal of Controlled Release. 223, p. 165-177 13 p.

Research output: Contribution to journalArticle

Clodronic Acid
Melanoma
Macrophages
Neoplasms
Lung

A novel liposomal Clodronate depletes tumor-associated macrophages in primary and metastatic melanoma: Anti-angiogenic and anti-tumor effects

Piaggio, F., Kondylis, V., Pastorino, F., Di Paolo, D., Perri, P., Cossu, I., Schorn, F., Marinaccio, C., Murgia, D., Daga, A., Raggi, F., Loi, M., Emionite, L., Ognio, E., Pasparakis, M., Ribatti, D., Ponzoni, M. & Brignole, C., Feb 10 2016, In : Journal of Controlled Release. 223, p. 165-177 13 p.

Research output: Contribution to journalArticle

Clodronic Acid
Melanoma
Macrophages
Neoplasms
Lung

Discovery of a novel glucose metabolism in cancer: The role of endoplasmic reticulum beyond glycolysis and pentose phosphate shunt

Marini, C., Ravera, S., Buschiazzo, A., Bianchi, G., Orengo, A. M., Bruno, S., Bottoni, G., Emionite, L., Pastorino, F., Monteverde, E., Garaboldi, L., Martella, R., Salani, B., Maggi, D., Ponzoni, M., Fais, F., Raffaghello, L. & Sambuceti, G., Apr 28 2016, In : Scientific Reports. 6, p. 25092

Research output: Contribution to journalArticle

Pentose Phosphate Pathway
Glycolysis
Endoplasmic Reticulum
Glucose
Fluorodeoxyglucose F18

Discovery of a novel glucose metabolism in cancer: The role of endoplasmic reticulum beyond glycolysis and pentose phosphate shunt

Marini, C., Ravera, S., Buschiazzo, A., Bianchi, G., Orengo, A. M., Bruno, S., Bottoni, G., Emionite, L., Pastorino, F., Monteverde, E., Garaboldi, L., Martella, R., Salani, B., Maggi, D., Ponzoni, M., Fais, F., Raffaghello, L. & Sambuceti, G., 2016, In : Scientific Reports. 6, 25092.

Research output: Contribution to journalArticle

Pentose Phosphate Pathway
Glycolysis
Endoplasmic Reticulum
Glucose
Fluorodeoxyglucose F18

Immunotherapy in the Treatment of Human Solid Tumors: Basic and Translational Aspects

Olive, D., Savoldo, B., Pastorino, F. & Castriconi, R., 2016, In : Journal of Immunology Research. 2016, 7853028.

Research output: Contribution to journalEditorial

PD-L1 expression in metastatic neuroblastoma as an additional mechanism for limiting immune surveillance

Dondero, A., Pastorino, F., Chiesa, M. D., Corrias, M. V., Morandi, F., Pistoia, V., Olive, D., Bellora, F., Locatelli, F., Castellano, A., Moretta, L., Moretta, A., Bottino, C. & Castriconi, R., 2016, In : OncoImmunology. 5, 1

Research output: Contribution to journalArticle

Neuroblastoma
Ligands
T-Lymphocytes
Cell Line
Immunotherapy

PD-L1 expression in metastatic neuroblastoma as an additional mechanism for limiting immune surveillance

Dondero, A., Pastorino, F., Chiesa, M. D., Corrias, M. V., Morandi, F., Pistoia, V., Olive, D., Bellora, F., Locatelli, F., Castellano, A., Moretta, L., Moretta, A., Bottino, C. & Castriconi, R., 2016, In : OncoImmunology. 5, 1

Research output: Contribution to journalArticle

Neuroblastoma
Ligands
T-Lymphocytes
Cell Line
Immunotherapy
2015

Anti-tumor effects of bak-proteoliposomes against glioblastoma

Liguori, L., Pastorino, F., Rousset, X., Alfano, S., Cortes, S., Emionite, L., Daga, A., Ponzoni, M. & Lenormand, J. L., Sep 1 2015, In : Molecules. 20, 9, p. 15893-15909 17 p.

Research output: Contribution to journalArticle

Tumors
Cells
bcl-2 Homologous Antagonist-Killer Protein
Bearings (structural)
proteoliposomes

Neuroblastoma-targeted nanocarriers improve drug delivery and penetration, delay tumor growth and abrogate metastatic diffusion

Cossu, I., Bottoni, G., Loi, M., Emionite, L., Bartolini, A., Di Paolo, D., Brignole, C., Piaggio, F., Perri, P., Sacchi, A., Curnis, F., Gagliani, M. C., Bruno, S., Marini, C., Gori, A., Longhi, R., Murgia, D., Sementa, A. R., Cilli, M., Tacchetti, C. & 5 others, Corti, A., Sambuceti, G., Marchiò, S., Ponzoni, M. & Pastorino, F., Nov 1 2015, In : Biomaterials. 68, p. 89-99 11 p.

Research output: Contribution to journalArticle

Neuroblastoma
Drug delivery
Tumors
Growth
Pharmaceutical Preparations

New therapeutic strategies in neuroblastoma: Combined targeting of a novel tyrosine kinase inhibitor and liposomal siRNAs against ALK

Di Paolo, D., Yang, D., Pastorino, F., Emionite, L., Cilli, M., Daga, A., Destafanis, E., Di Fiore, A., Piaggio, F., Brignole, C., Xu, X., Liang, C., Gibbons, J., Ponzoni, M. & Perri, P., 2015, In : Oncotarget. 6, 30, p. 28774-28789 16 p.

Research output: Contribution to journalArticle

Neuroblastoma
Protein-Tyrosine Kinases
Liposomes
Therapeutics
Heterografts
Neuroblastoma
Peptides
Neoplasms
Vascular Tissue Neoplasms
Ligands

Tumor vascular targeted liposomal-bortezomib minimizes side effects and increases therapeutic activity in human neuroblastoma

Zuccari, G., Milelli, A., Pastorino, F., Loi, M., Petretto, A., Parise, A., Marchetti, C., Minarini, A., Cilli, M., Emionite, L., Di Paolo, D., Brignole, C., Piaggio, F., Perri, P., Tumiatti, V., Pistoia, V., Pagnan, G. & Ponzoni, M., 2015, In : Journal of Controlled Release. 211, 1, p. 44-52 9 p.

Research output: Contribution to journalArticle

Therapeutic Uses
Neuroblastoma
Human Activities
Blood Vessels
Liposomes
2014

ALK-dependent control of hypoxia-inducible factors mediates tumor growth and metastasis

Martinengo, C., Poggio, T., Menotti, M., Scalzo, M. S., Mastini, C., Ambrogio, C., Pellegrino, E., Riera, L., Piva, R., Ribatti, D., Pastorino, F., Perri, P., Ponzoni, M., Wang, Q., Voena, C. & Chiarle, R., Nov 1 2014, In : Cancer Research. 74, 21, p. 6094-6106 13 p.

Research output: Contribution to journalArticle

Anaplastic Large-Cell Lymphoma
Neoplasm Metastasis
Non-Small Cell Lung Carcinoma
Growth
Neoplasms

STRAIL coupled to liposomes improves its pharmacokinetic profile and overcomes neuroblastoma tumour resistance in combination with Bortezomib

Loi, M., Becherini, P., Emionite, L., Giacomini, A., Cossu, I., Destefanis, E., Brignole, C., Di Paolo, D., Piaggio, F., Perri, P., Cilli, M., Pastorino, F. & Ponzoni, M., Oct 28 2014, In : Journal of Controlled Release. 192, p. 157-166 10 p.

Research output: Contribution to journalArticle

Neuroblastoma
Liposomes
Pharmacokinetics
Neoplasms
Pediatrics
2013

Enhanced anti-tumor and anti-angiogenic efficacy of a novel liposomal fenretinide on human neuroblastoma

Di Paolo, D., Pastorino, F., Zuccari, G., Caffa, I., Loi, M., Marimpietri, D., Brignole, C., Perri, P., Cilli, M., Nico, B., Ribatti, D., Pistoia, V., Ponzoni, M. & Pagnan, G., 2013, In : Journal of Controlled Release. 170, 3, p. 445-451 7 p.

Research output: Contribution to journalArticle

Fenretinide
Neuroblastoma
Neoplasms
NGR peptide
Pericytes

Multiplex analysis of carbohydrate/protein complex for neuroblastoma cells

Pastorino, F. & Simone, G., 2013, 17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013. Chemical and Biological Microsystems Society, Vol. 2. p. 1138-1140 3 p.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Carbohydrates
Proteins
Assays
Cells
Experiments
Neuroblastoma
Blood Vessels
Pharmaceutical Preparations
Neoplasms
NGR peptide

Neuroblastoma tumorigenesis is regulated through the Nm23-H1/h-Prune C-terminal interaction

Carotenuto, M., Pedone, E., Diana, D., De Antonellis, P., Džeroski, S., Marino, N., Navas, L., Di Dato, V., Scoppettuolo, M. N., Cimmino, F., Correale, S., Pirone, L., Monti, S. M., Bruder, E., Ženko, B., Slavkov, I., Pastorino, F., Ponzoni, M., Schulte, J. H., Schramm, A. & 8 others, Eggert, A., Westermann, F., Arrigoni, G., Accordi, B., Basso, G., Saviano, M., Fattorusso, R. & Zollo, M., 2013, In : Scientific Reports. 3, 1351.

Research output: Contribution to journalArticle

Neuroblastoma
Carcinogenesis
Peptides
Genes
Cell Movement

Novel phage display-derived neuroblastoma-targeting peptides potentiate the effect of drug nanocarriers in preclinical settings

Loi, M., Di Paolo, D., Soster, M., Brignole, C., Bartolini, A., Emionite, L., Sun, J., Becherini, P., Curnis, F., Petretto, A., Sani, M., Gori, A., Milanese, M., Gambini, C., Longhi, R., Cilli, M., Allen, T. M., Bussolino, F., Arap, W., Pasqualini, R. & 4 others, Corti, A., Ponzoni, M., Marchiò, S. & Pastorino, F., 2013, In : Journal of Controlled Release. 170, 2, p. 233-241 9 p.

Research output: Contribution to journalArticle

Neuroblastoma
Bacteriophages
Peptides
Pharmaceutical Preparations
Clone Cells
2012

Chromogranin A binds to αvβ6-integrin and promotes wound healing in mice

Curnis, F., Gasparri, A. M., Longhi, R., Colombo, B., D'Alessio, S., Pastorino, F., Ponzoni, M. & Corti, A., Aug 2012, In : Cellular and Molecular Life Sciences. 69, 16, p. 2791-2803 13 p.

Research output: Contribution to journalArticle

Chromogranin A
Integrins
Wound Healing
Keratinocytes
Neuroendocrine Cells

Targeted drug delivery and penetration into solid tumors

Corti, A., Pastorino, F., Curnis, F., Arap, W., Ponzoni, M. & Pasqualini, R., Sep 2012, In : Medicinal Research Reviews. 32, 5, p. 1078-1091 14 p.

Research output: Contribution to journalArticle

NGR peptide
Pharmaceutical Preparations
Neoplasms
Peptides
Biological Factors
2011

Frizzled receptor 6 marks rare, highly tumourigenic stem-like cells in mouse and human neuroblastomas

Cantilena, S., Pastorino, F., Pezzolo, A., Chayka, O., Pistoia, V., Ponzoni, M. & Sala, A., Dec 2011, In : Oncotarget. 2, 12, p. 976-983 8 p.

Research output: Contribution to journalArticle

Frizzled Receptors
Neuroblastoma
Stem Cells
Neural Crest
Wnt Receptors

Neuroblastoma-targeted nanoparticles entrapping siRNA specifically knockdown ALK

Di Paolo, D., Brignole, C., Pastorino, F., Carosio, R., Zorzoli, A., Rossi, M., Loi, M., Pagnan, G., Emionite, L., Cilli, M., Bruno, S., Chiarle, R., Allen, T. M., Ponzoni, M. & Perri, P., Jun 2011, In : Molecular Therapy. 19, 6, p. 1131-1140 10 p.

Research output: Contribution to journalArticle

Neuroblastoma
Nanoparticles
Small Interfering RNA
anaplastic lymphoma kinase
Liver

Potent and sustained inhibition of HIF-1α and downstream genes by a polyethyleneglycol-SN38 conjugate, EZN-2208, results in anti-angiogenic effects

Sapra, P., Kraft, P., Pastorino, F., Ribatti, D., Dumble, M., Mehlig, M., Wang, M., Ponzoni, M., Greenberger, L. M. & Horak, I. D., Sep 2011, In : Angiogenesis. 14, 3, p. 245-253 9 p.

Research output: Contribution to journalArticle

irinotecan
Genes
Tumors
Down-Regulation
Neoplasms

Selective therapeutic targeting of the anaplastic lymphoma kinase with liposomal siRNA induces apoptosis and inhibits angiogenesis in neuroblastoma

Di Paolo, D., Ambrogio, C., Pastorino, F., Brignole, C., Martinengo, C., Carosio, R., Loi, M., Pagnan, G., Emionite, L., Cilli, M., Ribatti, D., Allen, T. M., Chiarle, R., Ponzoni, M. & Perri, P., Dec 2011, In : Molecular Therapy. 19, 12, p. 2201-2212 12 p.

Research output: Contribution to journalArticle

Neuroblastoma
Small Interfering RNA
Apoptosis
Therapeutics
anaplastic lymphoma kinase

The use of the orthotopic model to validate antivascular therapies for cancer

Loi, M., di Paolo, D., Becherini, P., Zorzoli, A., Perri, P., Carosio, R., Cilli, M., Ribatti, D., Brignole, C., Pagnan, G., Ponzoni, M. & Pastorino, F., 2011, In : International Journal of Developmental Biology. 55, 4-5, p. 547-555 9 p.

Research output: Contribution to journalArticle

Neoplasms
Tumor Microenvironment
Therapeutics
Neoplasm Metastasis
2010

Combined targeting of perivascular and endothelial tumor cells enhances anti-tumor efficacy of liposomal chemotherapy in neuroblastoma

Loi, M., Marchiò, S., Becherini, P., Di Paolo, D., Soster, M., Curnis, F., Brignole, C., Pagnan, G., Perri, P., Caffa, I., Longhi, R., Nico, B., Bussolino, F., Gambini, C., Ribatti, D., Cilli, M., Arap, W., Pasqualini, R., Allen, T. M., Corti, A. & 2 others, Ponzoni, M. & Pastorino, F., Jul 2010, In : Journal of Controlled Release. 145, 1, p. 66-73 8 p.

Research output: Contribution to journalArticle

Glutamyl Aminopeptidase
Neuroblastoma
Endothelial Cells
CD13 Antigens
Drug Therapy

Critical role of flanking residues in NGR-to-isoDGR transition and CD13/integrin receptor switching

Curnis, F., Cattaneo, A., Longhi, R., Sacchi, A., Gasparri, A. M., Pastorino, F., Di Matteo, P., Traversari, C., Bachi, A., Ponzoni, M., Rizzardi, G. P. & Corti, A., Mar 19 2010, In : Journal of Biological Chemistry. 285, 12, p. 9114-9123 10 p.

Research output: Contribution to journalArticle

NGR peptide
Integrins
Tumors
Peptides
Cyclic Peptides

Enhanced anti-tumor activity of a new curcumin-related compound against melanoma and neuroblastoma cells

Pisano, M., Pagnan, G., Dettori, M. A., Cossu, S., Caffa, I., Sassu, I., Emionite, L., Fabbri, D., Cilli, M., Pastorino, F., Palmieri, G., Delogu, G., Ponzoni, M. & Rozzo, C., Jun 3 2010, In : Molecular Cancer. 9, 137.

Research output: Contribution to journalArticle

Curcumin
Neuroblastoma
Melanoma
Neoplasms
Growth

Therapeutic targeting of TLR9 inhibits cell growth and induces apoptosis in neuroblastoma

Brignole, C., Marimpietri, D., Di Paolo, D., Perri, P., Morandi, F., Pastorino, F., Zorzoli, A., Pagnan, G., Loi, M., Caffa, I., Erminio, G., Haupt, R., Gambini, C., Pistoia, V. & Ponzoni, M., Dec 1 2010, In : Cancer Research. 70, 23, p. 9816-9826 11 p.

Research output: Contribution to journalArticle

Toll-Like Receptor 9
Neuroblastoma
Apoptosis
Growth
Oligonucleotides

Tumor regression and curability of preclinical neuroblastoma models by PEGylated SN38 (EZN-2208), a novel topoisomerase I inhibitor

Pastorino, F., Loi, M., Sapra, P., Becherini, P., Cilli, M., Emionite, L., Ribatti, D., Greenberger, L. M., Horak, I. D. & Ponzoni, M., Oct 1 2010, In : Clinical Cancer Research. 16, 19, p. 4809-4821 13 p.

Research output: Contribution to journalArticle

Topoisomerase I Inhibitors
irinotecan
Neuroblastoma
Neoplasms
Topotecan
2009

Anti-IL-10R antibody improves the therapeutic efficacy of targeted liposomal oligonucleotides

Brignole, C., Marimpietri, D., Pastorino, F., Di Paolo, D., Pagnan, G., Loi, M., Piccardi, F., Cilli, M., Tradori-Cappai, A., Arrigoni, G., Pistoia, V. & Ponzoni, M., Sep 1 2009, In : Journal of Controlled Release. 138, 2, p. 122-127 6 p.

Research output: Contribution to journalArticle

Neuroblastoma
Oligonucleotides
Interleukin-10 Receptors
Antibodies
Therapeutics