20002020

Research output per year

If you made any changes in Pure these will be visible here soon.

Research Output

2020

A new human blood–retinal barrier model based on endothelial cells, pericytes, and astrocytes

Fresta, C. G., Fidilio, A., Caruso, G., Caraci, F., Giblin, F. J., Leggio, G. M., Salomone, S., Drago, F. & Bucolo, C., Mar 1 2020, In : International Journal of Molecular Sciences. 21, 5, 1636.

Research output: Contribution to journalArticle

Open Access

Antidepressant Drugs and Physical Activity: A Possible Synergism in the Treatment of Major Depression?

Guerrera, C. S., Furneri, G., Grasso, M., Caruso, G., Castellano, S., Drago, F., Di Nuovo, S. & Caraci, F., May 6 2020, In : Frontiers in Psychology. 11, 857.

Research output: Contribution to journalReview article

Open Access

A Path Toward Precision Medicine for Neuroinflammatory Mechanisms in Alzheimer's Disease

Alzheimer Precision Medicine Initiative (APMI), Mar 31 2020, In : Frontiers in Immunology. 11, 456.

Research output: Contribution to journalReview article

Open Access

Application of nanopharmaceutics for flibanserin brain delivery augmentation via the nasal route

Ahmed, O. A. A., Fahmy, U. A., Badr-Eldin, S. M., Aldawsari, H. M., Awan, Z. A., Asfour, H. Z., Kammoun, A. K., Caruso, G., Caraci, F., Alfarsi, A., Al-Ghamdi, R. A., Al-Ghamdi, R. A. & Alhakamy, N. A., Jul 2020, In : Nanomaterials. 10, 7, p. 1-15 15 p., 1270.

Research output: Contribution to journalArticle

Open Access

Chitosan coated microparticles enhance simvastatin colon targeting and pro-apoptotic activity

Alhakamy, N. A., Fahmy, U. A., Ahmed, O. A. A., Caruso, G., Caraci, F., Asfour, H. Z., Bakhrebah, M. A., Alomary, M. N., Abdulaal, W. H., Okbazghi, S. Z., Abdel-Naim, A. B., Eid, B. G., Aldawsari, H. M., Kurakula, M. & Mohamed, A. I., Apr 2020, In : Marine Drugs. 18, 4, 226.

Research output: Contribution to journalArticle

Open Access

Clinical and neurocognitive predictors of functional outcome in depressed patients with partial response to treatment: One year follow-up study

Castellano, S., Torrent, C., Petralia, M. C., Godos, J., Cantarella, R. A., Ventimiglia, A., De Vivo, S., Platania, S., Guarnera, M., Pirrone, C., Drago, F., Vieta, E., Di Nuovo, S., Popovic, D. & Caraci, F., 2020, In : Neuropsychiatric Disease and Treatment. 16, p. 589-595 7 p.

Research output: Contribution to journalArticle

Open Access

Diet and mental health: Review of the recent updates on molecular mechanisms

Godos, J., Currenti, W., Angelino, D., Mena, P., Castellano, S., Caraci, F., Galvano, F., Rio, D. D., Ferri, R. & Grosso, G., Apr 2020, In : Antioxidants. 9, 4, 346.

Research output: Contribution to journalReview article

Open Access

Modulation of Pro-Oxidant and Pro-Inflammatory Activities of M1 Macrophages by the Natural Dipeptide Carnosine

Fresta, C. G., Fidilio, A., Lazzarino, G., Musso, N., Grasso, M., Merlo, S., Amorini, A. M., Bucolo, C., Tavazzi, B., Lazzarino, G., Lunte, S. M., Caraci, F. & Caruso, G., Jan 25 2020, In : International Journal of Molecular Sciences. 21, 3

Research output: Contribution to journalArticle

Open Access

Modulation of sensitization processes in the management of pain and the importance of descending pathways: a role for tapentadol?

Caraci, F., Coluzzi, F., Marinangeli, F., Mercadante, S., Rinonapoli, G., Romualdi, P., Nicora, M. & Dickenson, A. H., Jun 2 2020, In : Current Medical Research and Opinion. 36, 6, p. 1015-1024 10 p.

Research output: Contribution to journalReview article

Specific dietary (Poly)phenols are associated with sleep quality in a cohort of Italian adults

Godos, J., Ferri, R., Castellano, S., Angelino, D., Mena, P., Del Rio, D., Caraci, F., Galvano, F. & Grosso, G., May 2020, In : Nutrients. 12, 5, 1226.

Research output: Contribution to journalArticle

Open Access

The Burden of Comorbidity Between Bipolar Spectrum and Obsessive-Compulsive Disorder in an Italian Community Survey

Carta, M. G., Fineberg, N., Moro, M. F., Preti, A., Romano, F., Balestrieri, M., Caraci, F., Dell'Osso, L., Disciascio, G., Drago, F., Hardoy, M. C., Roncone, R., Minerba, L., Faravelli, C. & Angst, J., Mar 31 2020, In : Frontiers in Psychiatry. 11, 188.

Research output: Contribution to journalArticle

Open Access
2019

Adherence to the Mediterranean Diet is Associated with Better Sleep Quality in Italian Adults

Godos, J., Ferri, R., Caraci, F., Cosentino, F. I. I., Castellano, S., Galvano, F. & Grosso, G., Apr 28 2019, In : Nutrients. 11, 5

Research output: Contribution to journalArticle

Open Access

Blood-based systems biology biomarkers for next-generation clinical trials in Alzheimer's disease


Hampel, H., Vergallo, A., Afshar, M., Akman-Anderson, L., Arenas, J., Benda, N., Batrla, R., Broich, K., Caraci, F., Cuello, A. C., Emanuele, E., Haberkamp, M., Kiddle, S. J., Lucía, A., Mapstone, M., Verdooner, S. R., Woodcock, J. & Lista, S., Jan 1 2019, In : Dialogues in Clinical Neuroscience. 21, 2, p. 177-191 15 p.

Research output: Contribution to journalArticle

Brain Aβ load association and sexual dimorphism of plasma BACE1 concentrations in cognitively normal individuals at risk for AD

the INSIGHT-preAD study group & Alzheimer Precision Medicine Initiative (APMI), Oct 1 2019, In : Alzheimer's and Dementia. 15, 10, p. 1274-1285 12 p.

Research output: Contribution to journalArticle

Open Access

Carnosine decreases PMA-induced oxidative stress and inflammation in murine macrophages

Caruso, G., Fresta, C. G., Fidilio, A., O'donnell, F., Musso, N., Lazzarino, G., Grasso, M., Amorini, A. M., Tascedda, F., Bucolo, C., Drago, F., Tavazzi, B., Lazzarino, G., Lunte, S. M. & Caraci, F., Aug 1 2019, In : Antioxidants. 8, 8, 281.

Research output: Contribution to journalArticle

Open Access

Carnosine Prevents Aβ-Induced Oxidative Stress and Inflammation in Microglial Cells: A Key Role of TGF-β1

Caruso, G., Fresta, C. G., Musso, N., Giambirtone, M., Grasso, M., Spampinato, S. F., Merlo, S., Drago, F., Lazzarino, G., Sortino, M. A., Lunte, S. M. & Caraci, F., Jan 17 2019, In : Cells. 8, 1

Research output: Contribution to journalArticle

Dietary Inflammatory Index and Sleep Quality in Southern Italian Adults

Godos, J., Ferri, R., Caraci, F., Cosentino, F. I. I., Castellano, S., Shivappa, N., Hebert, J. R., Galvano, F. & Grosso, G., Jun 13 2019, In : Nutrients. 11, 6

Research output: Contribution to journalArticle

Open Access

Differential default mode network trajectories in asymptomatic individuals at risk for Alzheimer's disease

INSIGHT-preAD study group & Alzheimer Precision Medicine Initiative (APMI), Jul 1 2019, In : Alzheimer's and Dementia. 15, 7, p. 940-950 11 p.

Research output: Contribution to journalArticle

Fluoxetine and vortioxetine reverse depressive-like phenotype and memory deficits induced by Aβ1-42 oligomers in mice: A key role of transforming growth factor-β1

Torrisi, S. A., Geraci, F., Tropea, M. R., Grasso, M., Caruso, G., Fidilio, A., Musso, N., Sanfilippo, G., Tascedda, F., Palmeri, A., Salomone, S., Drago, F., Puzzo, D., Leggio, G. M. & Caraci, F., Jan 1 2019, In : Frontiers in Pharmacology. 10, JUN, 693.

Research output: Contribution to journalArticle

Open Access

Impairment of quality of life associated with lifetime diagnosis of posttraumatic stress disorder in women-a national survey in italy

Sancassiani, F., Carmassi, C., Romano, F., Balestrieri, M., Caraci, F., Sciascio, G. D., Drago, F., Faravelli, C., Hardoy, M. C., Moro, M. F., Roncone, R., Preti, A. & Dell’osso, L., Jan 1 2019, In : Clinical Practice and Epidemiology in Mental Health. 15, 1, p. 38-43 6 p.

Research output: Contribution to journalArticle

Open Access

Inflammation as the common biological link between depression and cardiovascular diseases: Can carnosine exert a protective role?

Caruso, G., Fresta, C. G., Grasso, M., Santangelo, R., Lazzarino, G., Lunte, S. M. & Caraci, F., Jul 11 2019, In : Current Medicinal Chemistry.

Research output: Contribution to journalArticle

Rescue of noradrenergic system as a novel pharmacological strategy in the treatment of chronic pain: Focus on microglia activation

Caraci, F., Merlo, S., Drago, F., Caruso, G., Parenti, C. & Sortino, M. A., Jan 1 2019, In : Frontiers in Pharmacology. 10, SEP, 1024.

Research output: Contribution to journalReview article

Open Access

Simultaneous Activation of Mu and Delta Opioid Receptors Reduces Allodynia and Astrocytic Connexin 43 in an Animal Model of Neuropathic Pain

Vicario, N., Pasquinucci, L., Spitale, F. M., Chiechio, S., Turnaturi, R., Caraci, F., Tibullo, D., Avola, R., Gulino, R., Parenti, R. & Parenti, C., Jan 1 2019, In : Molecular Neurobiology.

Research output: Contribution to journalArticle

Simultaneous targeting of MOR/DOR: A useful strategy for inflammatory pain modulation

Pasquinucci, L., Turnaturi, R., Montenegro, L., Caraci, F., Chiechio, S. & Parenti, C., Mar 15 2019, In : European Journal of Pharmacology. 847, p. 97-102 6 p.

Research output: Contribution to journalArticle

Targeting mGlu receptors for optimization of antipsychotic activity and disease-modifying effect in schizophrenia

Nicoletti, F., Orlando, R., Menna, L. D., Cannella, M., Notartomaso, S., Mascio, G., Iacovelli, L., Matrisciano, F., Fazio, F., Caraci, F., Copani, A., Battaglia, G. & Bruno, V., Jan 1 2019, In : Frontiers in Psychiatry. 10, FEB, 49.

Research output: Contribution to journalArticle

Open Access

The many faces of mitochondrial dysfunction in depression: From pathology to treatment

Caruso, G., Benatti, C., Blom, J. M. C., Caraci, F. & Tascedda, F., Jan 1 2019, In : Frontiers in Pharmacology. 10, SEP, 995.

Research output: Contribution to journalReview article

Open Access

The prevalence of specific phobia by age in an italian nationwide survey: How much does it affect the quality of life?

Sancassiani, F., Romano, F., Balestrieri, M., Caraci, F., Di Sciascio, G., Drago, F., Hardoy, M. C., Moro, M. F., Roncone, R., Piras, M., Preti, A., Dell’osso, L., Faravelli, C. & Carta, M. G., Jan 1 2019, In : Clinical Practice and Epidemiology in Mental Health. 15, 1, p. 30-37 8 p.

Research output: Contribution to journalArticle

Open Access

β-amyloid and oxidative stress: Perspectives in drug development

Caruso, G., Spampinato, S. F., Cardaci, V., Caraci, F., Sortino, M. A. & Merlo, S., Jan 1 2019, In : Current Pharmaceutical Design. 25, 45, p. 4771-4781 11 p.

Research output: Contribution to journalReview article

2018

Clinically Relevant Drug Interactions with Anti-Alzheimer's Drugs

Caraci, F., Sultana, J., Drago, F. & Spina, E., 2018, In : CNS and Neurological Disorders - Drug Targets. 16, 4, p. 501-513 13 p.

Research output: Contribution to journalArticle

International union of basic and clinical pharmacology CIV: The neurobiology of treatment-resistant depression: From antidepressant classifications to novel pharmacological targets

Caraci, F., Calabrese, F., Molteni, R., Bartova, L., Dold, M., Leggio, G. M., Fabbri, C., Mendlewicz, J., Racagni, G., Kasper, S., Riva, M. A. & Drago, F., Jul 1 2018, In : Pharmacological Reviews. 70, 3, p. 475-504 30 p.

Research output: Contribution to journalReview article

Metabotropic glutamate receptors in glial cells: A new potential target for neuroprotection?

Spampinato, S. F., Copani, A., Nicoletti, F., Sortino, M. A. & Caraci, F., Nov 13 2018, In : Frontiers in Molecular Neuroscience. 11, 414.

Research output: Contribution to journalReview article

Neurobiological links between depression and AD: The role of TGF-β1 signaling as a new pharmacological target

Caraci, F., Spampinato, S. F., Morgese, M. G., Tascedda, F., Salluzzo, M. G., Giambirtone, M. C., Caruso, G., Munafò, A., Torrisi, S. A., Leggio, G. M., Trabace, L., Nicoletti, F., Drago, F., Sortino, M. A. & Copani, A., Jan 1 2018, (Accepted/In press) In : Pharmacological Research.

Research output: Contribution to journalArticle

Non-toxic engineered carbon nanodiamond concentrations induce oxidative/nitrosative stress, imbalance of energy metabolism, and mitochondrial dysfunction in microglial and alveolar basal epithelial cells article

Fresta, C. G., Chakraborty, A., Wijesinghe, M. B., Amorini, A. M., Lazzarino, G., Tavazzi, B., Lunte, S. M., Caraci, F., Dhar, P. & Caruso, G., 2018, In : Cell Death and Disease. 9, 2

Research output: Contribution to journalArticle

Sub-Toxic Human Amylin Fragment Concentrations Promote the Survival and Proliferation of SH-SY5Y Cells via the Release of VEGF and HspB5 from Endothelial RBE4 Cells

Caruso, G., Fresta, C. G., Lazzarino, G., Distefano, D. A., Parlascino, P., Lunte, S. M., Lazzarino, G. & Caraci, F., Nov 20 2018, In : International Journal of Molecular Sciences. 19, 11

Research output: Contribution to journalArticle

2017

A new nomenclature for classifying psychotropic drugs

Caraci, F., Enna, S. J., Zohar, J., Racagni, G., Zalsman, G., van den Brink, W., Kasper, S., Koob, G. F., Pariante, C. M., Piazza, P. V., Yamada, K., Spedding, M. & Drago, F., Aug 2017, In : British Journal of Clinical Pharmacology. 83, 8, p. 1614-1616 3 p.

Research output: Contribution to journalArticle

Buspirone counteracts MK-801-induced schizophrenia-like phenotypes through dopamine D3 receptor blockade

Torrisi, S. A., Salomone, S., Geraci, F., Caraci, F., Bucolo, C., Drago, F. & Leggio, G. M., Oct 4 2017, In : Frontiers in Pharmacology. 8, OCT, 710.

Research output: Contribution to journalArticle

Functional partnership between mGlu3 and mGlu5 metabotropic glutamate receptors in the central nervous system

Di Menna, L., Joffe, M. E., Iacovelli, L., Orlando, R., Lindsley, C. W., Mairesse, J., Gressèns, P., Cannella, M., Caraci, F., Copani, A., Bruno, V., Battaglia, G., Conn, P. J. & Nicoletti, F., Oct 25 2017, In : Neuropharmacology. 128, p. 301-313 13 p.

Research output: Contribution to journalArticle

Metabotropic glutamate receptors: the potential for therapeutic applications in Alzheimer's disease

Caraci, F. & Copani, A., Dec 23 2017, In : Current Opinion in Pharmacology. 38, p. 1-7 7 p.

Research output: Contribution to journalReview article

New drugs in psychiatry: focus on new pharmacological targets

Caraci, F., Leggio, G. M., Salomone, S. & Drago, F., 2017, In : F1000Research. 6, p. 397

Research output: Contribution to journalReview article

Preface Drug discovery in neurodegenerative disorders: a defeat for pharmacology?

Caraci, F., Kraneveld, A., Krzan, M. & Luca, M. D., Dec 15 2017, In : European Journal of Pharmacology. 817, p. 1

Research output: Contribution to journalArticle

Searching for new pharmacological targets for the treatment of Alzheimer's disease in Down syndrome

Caraci, F., Iulita, M. F., Pentz, R., Flores Aguilar, L., Orciani, C., Barone, C., Romano, C., Drago, F. & Cuello, A. C., 2017, (Accepted/In press) In : European Journal of Pharmacology.

Research output: Contribution to journalArticle

Silybin supplementation during HCV therapy with pegylated interferon-a plus ribavirin reduces depression and anxiety and increases work ability

Malaguarnera, G., Bertino, G., Chisari, G., Motta, M., Vecchio, M., Vacante, M., Caraci, F., Greco, C., Drago, F., Nunnari, G. & Malaguarnera, M., 2017, In : BMC Psychiatry. 16, 1, 398.

Research output: Contribution to journalReview article

Topical ocular delivery of TGF-β1 to the back of the eye: Implications in age-related neurodegenerative diseases

Platania, C. B. M., Fisichella, V., Fidilio, A., Geraci, F., Lazzara, F., Leggio, G. M., Salomone, S., Drago, F., Pignatello, R., Caraci, F. & Bucolo, C., Oct 1 2017, In : International Journal of Molecular Sciences. 18, 10, 2076.

Research output: Contribution to journalArticle

Open Access
File
9 Downloads (Pure)
2016

A link between nerve growth factor metabolic deregulation and amyloid-β-driven inflammation in down syndrome

Iulita, M. F., Caraci, F. & Cuello, A. C., May 1 2016, In : CNS and Neurological Disorders - Drug Targets. 15, 4, p. 434-447 14 p.

Research output: Contribution to journalArticle

An inflammatory and trophic disconnect biomarker profile revealed in Down syndrome plasma: Relation to cognitive decline and longitudinal evaluation

Iulita, M. F., Ower, A., Barone, C., Pentz, R., Gubert, P., Romano, C., Cantarella, R. A., Elia, F., Buono, S., Recupero, M., Castellano, S., Bosco, P., Di Nuovo, S., Drago, F., Caraci, F. & Cuello, A. C., Nov 1 2016, In : Alzheimer's and Dementia. 12, 11, p. 1132-1148 17 p.

Research output: Contribution to journalArticle

Fluoxetine Prevents Aβ1-42-Induced Toxicity via a Paracrine Signaling Mediated by Transforming-Growth-Factor-β1

Caraci, F., Tascedda, F., Merlo, S., Benatti, C., Spampinato, S. F., Munafò, A., Leggio, G. M., Brunello, N., Drago, F., Sortino, M. A. & Copani, A., 2016, In : Frontiers in Pharmacology. 7, p. 389

Research output: Contribution to journalArticle

Italian psychiatrists perception on cognitive symptoms in major depressive disorder

Albert, U., Brugnoli, R., Caraci, F., Di Sciascio, G., Tortorella, A., Vampini, C., Cataldo, N. & Pegoraro, V., Jan 2 2016, In : International Journal of Psychiatry in Clinical Practice. 20, 1, p. 2-9 8 p.

Research output: Contribution to journalArticle

Italian psychiatrists perception on cognitive symptoms in major depressive disorder

Albert, U. S., Brugnoli, R., Caraci, F., Dell'Osso, B., Di Sciascio, G., Tortorella, A., Vampini, C., Cataldo, N. & Pegoraro, V., 2016, In : International Journal of Psychiatry in Clinical Practice. 20, 1, p. 2-9 8 p.

Research output: Contribution to journalArticle