20002020

Research output per year

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Research Output

Article

Acetyl-L-carnitine supplementation during HCV therapy with pegylated interferon-α 2b plus ribavirin: Effect on work performance; a randomized clinical trial

Malaguarnera, G., Pennisi, M., Gagliano, C., Vacante, M., Malaguarnera, M., Salomone, S., Drago, F., Bertino, G., Caraci, F., Nunnari, G. & Malaguarnera, M., May 5 2014, In : Hepatitis Monthly. 14, 5

Research output: Contribution to journalArticle

Adherence to the Mediterranean Diet is Associated with Better Sleep Quality in Italian Adults

Godos, J., Ferri, R., Caraci, F., Cosentino, F. I. I., Castellano, S., Galvano, F. & Grosso, G., Apr 28 2019, In : Nutrients. 11, 5

Research output: Contribution to journalArticle

Open Access

A key role for TGF-β1 in hippocampal synaptic plasticity and memory

Caraci, F., Gulisano, W., Guida, C. A., Impellizzeri, A. A. R., Drago, F., Puzzo, D. & Palmeri, A., Jun 10 2015, In : Scientific Reports. 5, 11252.

Research output: Contribution to journalArticle

A link between nerve growth factor metabolic deregulation and amyloid-β-driven inflammation in down syndrome

Iulita, M. F., Caraci, F. & Cuello, A. C., May 1 2016, In : CNS and Neurological Disorders - Drug Targets. 15, 4, p. 434-447 14 p.

Research output: Contribution to journalArticle

Allele ε4 of APOE is a stronger predictor of Alzheimer risk in Sicily than in continental South Italy

Bosco, P., Guéant-Rodríguez, R. M., Anello, G., Spada, R. S., Romano, A., Caraci, F., Ferri, R. & Guéant, J. L., Nov 18 2005, In : Neuroscience Letters. 388, 3, p. 168-172 5 p.

Research output: Contribution to journalArticle

A new 6-bp SOX-3 polyalanine tract deletion does not segregate with mental retardation

Salemi, M., Romano, C., Ragusa, L., Di Vita, G., Salluzzo, R., Oteri, I., Trovato, M. L., Romano, C., Caraci, F., Nicoletti, F. & Bosco, P., Jun 2007, In : Genetic Testing. 11, 2, p. 124-127 4 p.

Research output: Contribution to journalArticle

A new nomenclature for classifying psychotropic drugs

Caraci, F., Enna, S. J., Zohar, J., Racagni, G., Zalsman, G., van den Brink, W., Kasper, S., Koob, G. F., Pariante, C. M., Piazza, P. V., Yamada, K., Spedding, M. & Drago, F., Aug 2017, In : British Journal of Clinical Pharmacology. 83, 8, p. 1614-1616 3 p.

Research output: Contribution to journalArticle

An inflammatory and trophic disconnect biomarker profile revealed in Down syndrome plasma: Relation to cognitive decline and longitudinal evaluation

Iulita, M. F., Ower, A., Barone, C., Pentz, R., Gubert, P., Romano, C., Cantarella, R. A., Elia, F., Buono, S., Recupero, M., Castellano, S., Bosco, P., Di Nuovo, S., Drago, F., Caraci, F. & Cuello, A. C., Nov 1 2016, In : Alzheimer's and Dementia. 12, 11, p. 1132-1148 17 p.

Research output: Contribution to journalArticle

Assessment of immune system function in schizophrenic and depressed patients treated with ω-3 fatty acids

Rapisarda, V., Petralia, A., De Pasquale, C., Caraci, F., Sambataro, F., Nicoletti, V. G., Petriglieri, G. & Giuffrida-Stella, A. M., 2000, In : Italian Journal of Psychiatry and Behavioural Sciences. 10, 1, p. 22-25 4 p.

Research output: Contribution to journalArticle

Association of homocystein (but not MTHFR 677 C>T, MTR 2756 A>G, MTRR 66A>G and TCN2 776 C>G) with ischaemic cerebrovascular disease in Sicily

Bosco, P., Guéant-Rodriguez, R. M., Anello, G., Spada, R., Romano, A., Fajardo, A., Caraci, F., Ferri, R. & Guéant, J. L., Aug 2006, In : Thrombosis and Haemostasis. 96, 2, p. 154-159 6 p.

Research output: Contribution to journalArticle

Association of IL-1 RN*2 allele and methionine synthase 2756 AA genotype with dementia severity of spradic Alzheimer's disease

Bosco, P., Guéant-Rodríguez, R. M., Anello, G., Romano, A., Namour, B., Spada, R. S., Caraci, F., Tringali, G., Ferri, R. & Guéant, J. L., Jul 2004, In : Journal of Neurology, Neurosurgery and Psychiatry. 75, 7, p. 1036-1038 3 p.

Research output: Contribution to journalArticle

Beta-Amyloid monomer and insulin/IGF-1 signaling in Alzheimer's disease

Giuffrida, M. L., Tomasello, F., Caraci, F., Chiechio, S., Nicoletti, F. & Copani, A., 2012, In : Molecular Neurobiology. 46, 3, p. 605-613 9 p.

Research output: Contribution to journalArticle

Blood-based systems biology biomarkers for next-generation clinical trials in Alzheimer's disease


Hampel, H., Vergallo, A., Afshar, M., Akman-Anderson, L., Arenas, J., Benda, N., Batrla, R., Broich, K., Caraci, F., Cuello, A. C., Emanuele, E., Haberkamp, M., Kiddle, S. J., Lucía, A., Mapstone, M., Verdooner, S. R., Woodcock, J. & Lista, S., Jan 1 2019, In : Dialogues in Clinical Neuroscience. 21, 2, p. 177-191 15 p.

Research output: Contribution to journalArticle

Brain Aβ load association and sexual dimorphism of plasma BACE1 concentrations in cognitively normal individuals at risk for AD

the INSIGHT-preAD study group & Alzheimer Precision Medicine Initiative (APMI), Oct 1 2019, In : Alzheimer's and Dementia. 15, 10, p. 1274-1285 12 p.

Research output: Contribution to journalArticle

Open Access

Buspirone counteracts MK-801-induced schizophrenia-like phenotypes through dopamine D3 receptor blockade

Torrisi, S. A., Salomone, S., Geraci, F., Caraci, F., Bucolo, C., Drago, F. & Leggio, G. M., Oct 4 2017, In : Frontiers in Pharmacology. 8, OCT, 710.

Research output: Contribution to journalArticle

Carnosine decreases PMA-induced oxidative stress and inflammation in murine macrophages

Caruso, G., Fresta, C. G., Fidilio, A., O'donnell, F., Musso, N., Lazzarino, G., Grasso, M., Amorini, A. M., Tascedda, F., Bucolo, C., Drago, F., Tavazzi, B., Lazzarino, G., Lunte, S. M. & Caraci, F., Aug 1 2019, In : Antioxidants. 8, 8, 281.

Research output: Contribution to journalArticle

Open Access

Carnosine Prevents Aβ-Induced Oxidative Stress and Inflammation in Microglial Cells: A Key Role of TGF-β1

Caruso, G., Fresta, C. G., Musso, N., Giambirtone, M., Grasso, M., Spampinato, S. F., Merlo, S., Drago, F., Lazzarino, G., Sortino, M. A., Lunte, S. M. & Caraci, F., Jan 17 2019, In : Cells. 8, 1

Research output: Contribution to journalArticle

Central serotonin2B receptor blockade inhibits cocaine-induced hyperlocomotion independently of changes of subcortical dopamine outflow

Devroye, C., Cathala, A., Di Marco, B., Caraci, F., Drago, F., Piazza, P. V. & Spampinato, U., Oct 1 2015, In : Neuropharmacology. 97, p. 329-337 9 p.

Research output: Contribution to journalArticle

Clinically Relevant Drug Interactions with Anti-Alzheimer's Drugs

Caraci, F., Sultana, J., Drago, F. & Spina, E., 2018, In : CNS and Neurological Disorders - Drug Targets. 16, 4, p. 501-513 13 p.

Research output: Contribution to journalArticle

Clinically significant drug interactions with newer antidepressants

Spina, E., Trifirò, G. & Caraci, F., 2012, In : CNS Drugs. 26, 1, p. 39-67 29 p.

Research output: Contribution to journalArticle

Clinical pharmacology of novel anti-Alzheimer disease modifying medications

Caraci, F., Bosco, P., Leggio, G. M., Malaguarnera, M., Drago, F., Bucolo, C. & Salomone, S., 2013, In : Current Topics in Medicinal Chemistry. 13, 15, p. 1853-1863 11 p.

Research output: Contribution to journalArticle

Comparing factor structure of the mood disorder questionnaire (MDQ): In italy sexual behavior is euphoric but in asia mysterious and forbidden

Carta, M. G., Massidda, D., Moro, M. F., Aguglia, E., Balestrieri, M., Caraci, F., Dell'Osso, L., Di Sciascio, G., Drago, F., Faravelli, C., Hardoy, M. C., Calò, S., Pollice, R., Fortezzo, A. & Akiskal, H., Feb 2014, In : Journal of Affective Disorders. 155, 1, p. 96-103 8 p.

Research output: Contribution to journalArticle

Depression and Alzheimer's disease: Neurobiological links and common pharmacological targets

Caraci, F., Copani, A., Nicoletti, F. & Drago, F., Jan 10 2010, In : European Journal of Pharmacology. 626, 1, p. 64-71 8 p.

Research output: Contribution to journalArticle

Design and synthesis of new trehalose-conjugated pentapeptides as inhibitors of Aβ(1-42) fibrillogenesis and toxicity

De Bona, P., Giuffrida, M. L., Caraci, F., Copani, A., Pignataro, B., Attanasio, F., Cataldo, S., Pappalardo, G. & Rizzarelli, E., 2009, In : Journal of Peptide Science. 15, 3, p. 220-228 9 p.

Research output: Contribution to journalArticle

Dietary Inflammatory Index and Sleep Quality in Southern Italian Adults

Godos, J., Ferri, R., Caraci, F., Cosentino, F. I. I., Castellano, S., Shivappa, N., Hebert, J. R., Galvano, F. & Grosso, G., Jun 13 2019, In : Nutrients. 11, 6

Research output: Contribution to journalArticle

Open Access

Differential default mode network trajectories in asymptomatic individuals at risk for Alzheimer's disease

INSIGHT-preAD study group & Alzheimer Precision Medicine Initiative (APMI), Jul 1 2019, In : Alzheimer's and Dementia. 15, 7, p. 940-950 11 p.

Research output: Contribution to journalArticle

Differential expression of PARP1 mRNA in leucocytes of patients with Down's syndrome

Salemi, M., Barone, C., Romano, C., Ridolfo, F., Gulotta, E., Scavuzzo, C., Salluzzo, M. G., Giambirtone, M., Caraci, F., Romano, C. & Bosco, P., Dec 2011, In : Journal of Genetics. 90, 3, p. 469-472 4 p.

Research output: Contribution to journalArticle

DNA polymerase-β is expressed early in neurons of Alzheimer's disease brain and is loaded into DNA replication forks in neurons challenged with β-amyloid

Copani, A., Hoozemans, J. J. M., Caraci, F., Calafiore, M., Van Haastert, E. S., Veerhuis, R., Rozemuller, A. J. M., Aronica, E., Sortino, M. A. & Nicoletti, F., Oct 25 2006, In : Journal of Neuroscience. 26, 43, p. 10949-10957 9 p.

Research output: Contribution to journalArticle

Does Mood Disorder Questionnaire identify sub-threshold bipolarity? Evidence studying worsening of quality of life

Carta, M. G., Norcini-Pala, A., Moro, M. F., Balestrieri, M., Caraci, F., Dell'Osso, L., Sciascio, G. D., Faravelli, C., Hardoy, M. C., Aguglia, E., Roncone, R., Nardi, A. E. & Drago, F., Sep 1 2015, In : Journal of Affective Disorders. 183, p. 173-178 6 p., 7435.

Research output: Contribution to journalArticle

Dopamine D3 receptor as a new pharmacological target for the treatment of depression

Leggio, G. M., Salomone, S., Bucolo, C., Platania, C., Micale, V., Caraci, F. & Drago, F., 2013, In : European Journal of Pharmacology. 719, 1-3, p. 25-33 9 p.

Research output: Contribution to journalArticle

Dopamine D3 receptor-dependent changes in alpha6 GABAA subunit expression in striatum modulate anxiety-like behaviour: Responsiveness and tolerance to diazepam

Leggio, G. M., Torrisi, S. A., Castorina, A., Platania, C. B. M., Impellizzeri, A. A. R., Fidilio, A., Caraci, F., Bucolo, C., Drago, F. & Salomone, S., Sep 1 2015, In : European Neuropsychopharmacology. 25, 9, p. 1427-1436 10 p.

Research output: Contribution to journalArticle

Dysfunction of TGF-β1 signaling in Alzheimer's disease: Perspectives for neuroprotection

Caraci, F., Spampinato, S., Sortino, M. A., Bosco, P., Battaglia, G., Bruno, V., Drago, F., Nicoletti, F. & Copani, A., Jan 2012, In : Cell & Tissue Research. 347, 1, p. 291-301 11 p.

Research output: Contribution to journalArticle

Eating disorders as a public health issue: Prevalence and attributable impairment of quality of life in an Italian community sample

Carta, M. G., Preti, A., Moro, M. F., Aguglia, E., Balestrieri, M., Caraci, F., Dell'Osso, L., Di Sciascio, G., Drago, F., Faravelli, C., Hardoy, M. C., D'Aloja, E., Cossu, G., Calò, S., Palumbo, G. & Bhugra, D., 2014, In : International Review of Psychiatry. 26, 4, p. 486-492 7 p.

Research output: Contribution to journalArticle

Effects of phenformin on the proliferation of human tumor cell lines

Caraci, F., Chisari, M., Frasca, G., Chiechio, S., Salomone, S., Pinto, A., Sortino, M. A. & Bianchi, A., Dec 19 2003, In : Life Sciences. 74, 5, p. 643-650 8 p.

Research output: Contribution to journalArticle

Efficacy and tolerability of Hypericum extract for the treatment of mild to moderate depression

Kasper, S., Caraci, F., Forti, B., Drago, F. & Aguglia, E., Nov 2010, In : European Neuropsychopharmacology. 20, 11, p. 747-765 19 p.

Research output: Contribution to journalArticle

Enhanced expression of ERα in astrocytes modifies the response of cortical neurons to β-amyloid toxicity

Carbonaro, V., Caraci, F., Giuffrida, M. L., Merlo, S., Canonico, P. L., Drago, F., Copani, A. & Sortino, M. A., Mar 2009, In : Neurobiology of Disease. 33, 3, p. 415-421 7 p.

Research output: Contribution to journalArticle

Epigenetic drugs for Alzheimer's disease: Hopes and challenges

Caraci, F., Leggio, G. M., Drago, F. & Salomone, S., Apr 2013, In : British Journal of Clinical Pharmacology. 75, 4, p. 1154-1155 2 p.

Research output: Contribution to journalArticle

Erratum: Quality of Life and Urban / Rural Living: Preliminary Results of a Community Survey in Italy (Clinical Practice & Epidemiology in Mental Health (2012) 8 (169-174))

Carta, M. G., Aguglia, E., Caraci, F., Dell'Osso, L., Di Sciascio, G., Drago, F., Del Giudice, E., Faravelli, C., Hardoy, M. C., Lecca, M. E., Moro, M. F., Calò, S., Casacchia, M., Angermeyer, M. C. & Balestrieri, M., 2013, In : Clinical Practice and Epidemiology in Mental Health. 9, p. 148 1 p.

Research output: Contribution to journalArticle

Estrogen receptors and type 1 metabotropic glutamate receptors are interdependent in protecting cortical neurons against β-amyloid toxicity

Spampinato, S. F., Molinaro, G., Merlo, S., Iacovelli, L., Caraci, F., Battaglia, G., Nicoletti, F., Bruno, V. & Sortino, M. A., Jan 2012, In : Molecular Pharmacology. 81, 1, p. 12-20 9 p.

Research output: Contribution to journalArticle

Expression of LDOC1 mRNA in leucocytes of patients with Down's syndrome

Salemi, M., Barone, C., Romano, C., Ridolfo, F., Salluzzo, R., Scillato, F., Scavuzzo, C., Caraci, F., Calogero, A. E., Romano, C. & Bosco, P., Apr 2012, In : Journal of Genetics. 91, 1, p. 95-98 4 p.

Research output: Contribution to journalArticle

Fingolimod protects cultured cortical neurons against excitotoxic death

Di Menna, L., Molinaro, G., Di Nuzzo, L., Riozzi, B., Zappulla, C., Pozzilli, C., Turrini, R., Caraci, F., Copani, A., Battaglia, G., Nicoletti, F. & Bruno, V., Jan 2013, In : Pharmacological Research. 67, 1, p. 1-9 9 p.

Research output: Contribution to journalArticle

Fluoxetine and vortioxetine reverse depressive-like phenotype and memory deficits induced by Aβ1-42 oligomers in mice: A key role of transforming growth factor-β1

Torrisi, S. A., Geraci, F., Tropea, M. R., Grasso, M., Caruso, G., Fidilio, A., Musso, N., Sanfilippo, G., Tascedda, F., Palmeri, A., Salomone, S., Drago, F., Puzzo, D., Leggio, G. M. & Caraci, F., Jan 1 2019, In : Frontiers in Pharmacology. 10, JUN, 693.

Research output: Contribution to journalArticle

Open Access

Fluoxetine Prevents Aβ1-42-Induced Toxicity via a Paracrine Signaling Mediated by Transforming-Growth-Factor-β1

Caraci, F., Tascedda, F., Merlo, S., Benatti, C., Spampinato, S. F., Munafò, A., Leggio, G. M., Brunello, N., Drago, F., Sortino, M. A. & Copani, A., 2016, In : Frontiers in Pharmacology. 7, p. 389

Research output: Contribution to journalArticle

Folate status in type 2 diabetic patients with and without retinopathy

Malaguarnera, G., Gagliano, C., Salomone, S., Giordano, M., Bucolo, C., Pappalardo, A., Drago, F., Caraci, F., Avitabile, T. & Motta, M., Aug 7 2015, In : Clinical Ophthalmology. 9, p. 1437-1442 6 p.

Research output: Contribution to journalArticle

Functional partnership between mGlu3 and mGlu5 metabotropic glutamate receptors in the central nervous system

Di Menna, L., Joffe, M. E., Iacovelli, L., Orlando, R., Lindsley, C. W., Mairesse, J., Gressèns, P., Cannella, M., Caraci, F., Copani, A., Bruno, V., Battaglia, G., Conn, P. J. & Nicoletti, F., Oct 25 2017, In : Neuropharmacology. 128, p. 301-313 13 p.

Research output: Contribution to journalArticle

Homocysteine and methylenetetrahydrofolate reductase polymorphism in Alzheimer's disease

Anello, G., Guéant-Rodríguez, R. M., Bosco, P., Guéant, J. L., Romano, A., Namour, B., Spada, R., Caraci, F., Pourié, G., Daval, J. L. & Ferri, R., Apr 9 2004, In : NeuroReport. 15, 5, p. 859-861 3 p.

Research output: Contribution to journalArticle

Homocysteine serum levels in diabetic patients with non proliferative, proliferative and without retinopathy

Malaguarnera, G., Gagliano, C., Giordano, M., Salomone, S., Vacante, M., Bucolo, C., Caraci, F., Reibaldi, M., Drago, F., Avitabile, T. & Motta, M., 2014, In : BioMed Research International. 2014, 191497.

Research output: Contribution to journalArticle

Impairment of quality of life associated with lifetime diagnosis of posttraumatic stress disorder in women-a national survey in italy

Sancassiani, F., Carmassi, C., Romano, F., Balestrieri, M., Caraci, F., Sciascio, G. D., Drago, F., Faravelli, C., Hardoy, M. C., Moro, M. F., Roncone, R., Preti, A. & Dell’osso, L., Jan 1 2019, In : Clinical Practice and Epidemiology in Mental Health. 15, 1, p. 38-43 6 p.

Research output: Contribution to journalArticle

Open Access

Induction of Dickkopf-1, a negative modulator of the Wnt pathway, is associated with neuronal degeneration in Alzheimer's brain

Caricasole, A., Copani, A., Caraci, F., Aronica, E., Rozemuller, A. J., Caruso, A., Storto, M., Gaviraghi, G., Terstappen, G. C. & Nicoletti, F., Jun 30 2004, In : Journal of Neuroscience. 24, 26, p. 6021-6027 7 p.

Research output: Contribution to journalArticle

Induction of the Wnt antagonist dickkopf-1 is involved in stress-induced hippocampal damage

Matrisciano, F., Busceti, C. L., Bucci, D., Orlando, R., Caruso, A., Molinaro, G., Cappuccio, I., Riozzi, B., Gradini, R., Motolese, M., Caraci, F., Copani, A., Scaccianoce, S., Melchiorri, D., Bruno, V., Battaglia, G. & Nicoletti, F., 2011, In : PLoS One. 6, 1, e16447.

Research output: Contribution to journalArticle