20002020

Research output per year

If you made any changes in Pure these will be visible here soon.

Research Output

Filter
Article
2020

Application of nanopharmaceutics for flibanserin brain delivery augmentation via the nasal route

Ahmed, O. A. A., Fahmy, U. A., Badr-Eldin, S. M., Aldawsari, H. M., Awan, Z. A., Asfour, H. Z., Kammoun, A. K., Caruso, G., Caraci, F., Alfarsi, A., Al-Ghamdi, R. A., Al-Ghamdi, R. A. & Alhakamy, N. A., Jul 2020, In : Nanomaterials. 10, 7, p. 1-15 15 p., 1270.

Research output: Contribution to journalArticle

Open Access

Modulation of Pro-Oxidant and Pro-Inflammatory Activities of M1 Macrophages by the Natural Dipeptide Carnosine

Fresta, C. G., Fidilio, A., Lazzarino, G., Musso, N., Grasso, M., Merlo, S., Amorini, A. M., Bucolo, C., Tavazzi, B., Lazzarino, G., Lunte, S. M., Caraci, F. & Caruso, G., Jan 25 2020, In : International Journal of Molecular Sciences. 21, 3

Research output: Contribution to journalArticle

Open Access
2019

Adherence to the Mediterranean Diet is Associated with Better Sleep Quality in Italian Adults

Godos, J., Ferri, R., Caraci, F., Cosentino, F. I. I., Castellano, S., Galvano, F. & Grosso, G., Apr 28 2019, In : Nutrients. 11, 5

Research output: Contribution to journalArticle

Open Access

Blood-based systems biology biomarkers for next-generation clinical trials in Alzheimer's disease


Hampel, H., Vergallo, A., Afshar, M., Akman-Anderson, L., Arenas, J., Benda, N., Batrla, R., Broich, K., Caraci, F., Cuello, A. C., Emanuele, E., Haberkamp, M., Kiddle, S. J., Lucía, A., Mapstone, M., Verdooner, S. R., Woodcock, J. & Lista, S., Jan 1 2019, In : Dialogues in Clinical Neuroscience. 21, 2, p. 177-191 15 p.

Research output: Contribution to journalArticle

Brain Aβ load association and sexual dimorphism of plasma BACE1 concentrations in cognitively normal individuals at risk for AD

the INSIGHT-preAD study group & Alzheimer Precision Medicine Initiative (APMI), Oct 1 2019, In : Alzheimer's and Dementia. 15, 10, p. 1274-1285 12 p.

Research output: Contribution to journalArticle

Open Access

Carnosine decreases PMA-induced oxidative stress and inflammation in murine macrophages

Caruso, G., Fresta, C. G., Fidilio, A., O'donnell, F., Musso, N., Lazzarino, G., Grasso, M., Amorini, A. M., Tascedda, F., Bucolo, C., Drago, F., Tavazzi, B., Lazzarino, G., Lunte, S. M. & Caraci, F., Aug 1 2019, In : Antioxidants. 8, 8, 281.

Research output: Contribution to journalArticle

Open Access

Carnosine Prevents Aβ-Induced Oxidative Stress and Inflammation in Microglial Cells: A Key Role of TGF-β1

Caruso, G., Fresta, C. G., Musso, N., Giambirtone, M., Grasso, M., Spampinato, S. F., Merlo, S., Drago, F., Lazzarino, G., Sortino, M. A., Lunte, S. M. & Caraci, F., Jan 17 2019, In : Cells. 8, 1

Research output: Contribution to journalArticle

Dietary Inflammatory Index and Sleep Quality in Southern Italian Adults

Godos, J., Ferri, R., Caraci, F., Cosentino, F. I. I., Castellano, S., Shivappa, N., Hebert, J. R., Galvano, F. & Grosso, G., Jun 13 2019, In : Nutrients. 11, 6

Research output: Contribution to journalArticle

Open Access

Differential default mode network trajectories in asymptomatic individuals at risk for Alzheimer's disease

INSIGHT-preAD study group & Alzheimer Precision Medicine Initiative (APMI), Jul 1 2019, In : Alzheimer's and Dementia. 15, 7, p. 940-950 11 p.

Research output: Contribution to journalArticle

Fluoxetine and vortioxetine reverse depressive-like phenotype and memory deficits induced by Aβ1-42 oligomers in mice: A key role of transforming growth factor-β1

Torrisi, S. A., Geraci, F., Tropea, M. R., Grasso, M., Caruso, G., Fidilio, A., Musso, N., Sanfilippo, G., Tascedda, F., Palmeri, A., Salomone, S., Drago, F., Puzzo, D., Leggio, G. M. & Caraci, F., Jan 1 2019, In : Frontiers in Pharmacology. 10, JUN, 693.

Research output: Contribution to journalArticle

Open Access

Impairment of quality of life associated with lifetime diagnosis of posttraumatic stress disorder in women-a national survey in italy

Sancassiani, F., Carmassi, C., Romano, F., Balestrieri, M., Caraci, F., Sciascio, G. D., Drago, F., Faravelli, C., Hardoy, M. C., Moro, M. F., Roncone, R., Preti, A. & Dell’osso, L., Jan 1 2019, In : Clinical Practice and Epidemiology in Mental Health. 15, 1, p. 38-43 6 p.

Research output: Contribution to journalArticle

Open Access

Inflammation as the common biological link between depression and cardiovascular diseases: Can carnosine exert a protective role?

Caruso, G., Fresta, C. G., Grasso, M., Santangelo, R., Lazzarino, G., Lunte, S. M. & Caraci, F., Jul 11 2019, In : Current Medicinal Chemistry.

Research output: Contribution to journalArticle

Simultaneous Activation of Mu and Delta Opioid Receptors Reduces Allodynia and Astrocytic Connexin 43 in an Animal Model of Neuropathic Pain

Vicario, N., Pasquinucci, L., Spitale, F. M., Chiechio, S., Turnaturi, R., Caraci, F., Tibullo, D., Avola, R., Gulino, R., Parenti, R. & Parenti, C., Jan 1 2019, In : Molecular Neurobiology.

Research output: Contribution to journalArticle

Simultaneous targeting of MOR/DOR: A useful strategy for inflammatory pain modulation

Pasquinucci, L., Turnaturi, R., Montenegro, L., Caraci, F., Chiechio, S. & Parenti, C., Mar 15 2019, In : European Journal of Pharmacology. 847, p. 97-102 6 p.

Research output: Contribution to journalArticle

Targeting mGlu receptors for optimization of antipsychotic activity and disease-modifying effect in schizophrenia

Nicoletti, F., Orlando, R., Menna, L. D., Cannella, M., Notartomaso, S., Mascio, G., Iacovelli, L., Matrisciano, F., Fazio, F., Caraci, F., Copani, A., Battaglia, G. & Bruno, V., Jan 1 2019, In : Frontiers in Psychiatry. 10, FEB, 49.

Research output: Contribution to journalArticle

Open Access

The prevalence of specific phobia by age in an italian nationwide survey: How much does it affect the quality of life?

Sancassiani, F., Romano, F., Balestrieri, M., Caraci, F., Di Sciascio, G., Drago, F., Hardoy, M. C., Moro, M. F., Roncone, R., Piras, M., Preti, A., Dell’osso, L., Faravelli, C. & Carta, M. G., Jan 1 2019, In : Clinical Practice and Epidemiology in Mental Health. 15, 1, p. 30-37 8 p.

Research output: Contribution to journalArticle

Open Access
2018

Clinically Relevant Drug Interactions with Anti-Alzheimer's Drugs

Caraci, F., Sultana, J., Drago, F. & Spina, E., 2018, In : CNS and Neurological Disorders - Drug Targets. 16, 4, p. 501-513 13 p.

Research output: Contribution to journalArticle

Neurobiological links between depression and AD: The role of TGF-β1 signaling as a new pharmacological target

Caraci, F., Spampinato, S. F., Morgese, M. G., Tascedda, F., Salluzzo, M. G., Giambirtone, M. C., Caruso, G., Munafò, A., Torrisi, S. A., Leggio, G. M., Trabace, L., Nicoletti, F., Drago, F., Sortino, M. A. & Copani, A., Jan 1 2018, (Accepted/In press) In : Pharmacological Research.

Research output: Contribution to journalArticle

Non-toxic engineered carbon nanodiamond concentrations induce oxidative/nitrosative stress, imbalance of energy metabolism, and mitochondrial dysfunction in microglial and alveolar basal epithelial cells article

Fresta, C. G., Chakraborty, A., Wijesinghe, M. B., Amorini, A. M., Lazzarino, G., Tavazzi, B., Lunte, S. M., Caraci, F., Dhar, P. & Caruso, G., 2018, In : Cell Death and Disease. 9, 2

Research output: Contribution to journalArticle

Sub-Toxic Human Amylin Fragment Concentrations Promote the Survival and Proliferation of SH-SY5Y Cells via the Release of VEGF and HspB5 from Endothelial RBE4 Cells

Caruso, G., Fresta, C. G., Lazzarino, G., Distefano, D. A., Parlascino, P., Lunte, S. M., Lazzarino, G. & Caraci, F., Nov 20 2018, In : International Journal of Molecular Sciences. 19, 11

Research output: Contribution to journalArticle

2017

A new nomenclature for classifying psychotropic drugs

Caraci, F., Enna, S. J., Zohar, J., Racagni, G., Zalsman, G., van den Brink, W., Kasper, S., Koob, G. F., Pariante, C. M., Piazza, P. V., Yamada, K., Spedding, M. & Drago, F., Aug 2017, In : British Journal of Clinical Pharmacology. 83, 8, p. 1614-1616 3 p.

Research output: Contribution to journalArticle

Buspirone counteracts MK-801-induced schizophrenia-like phenotypes through dopamine D3 receptor blockade

Torrisi, S. A., Salomone, S., Geraci, F., Caraci, F., Bucolo, C., Drago, F. & Leggio, G. M., Oct 4 2017, In : Frontiers in Pharmacology. 8, OCT, 710.

Research output: Contribution to journalArticle

Functional partnership between mGlu3 and mGlu5 metabotropic glutamate receptors in the central nervous system

Di Menna, L., Joffe, M. E., Iacovelli, L., Orlando, R., Lindsley, C. W., Mairesse, J., Gressèns, P., Cannella, M., Caraci, F., Copani, A., Bruno, V., Battaglia, G., Conn, P. J. & Nicoletti, F., Oct 25 2017, In : Neuropharmacology. 128, p. 301-313 13 p.

Research output: Contribution to journalArticle

Preface Drug discovery in neurodegenerative disorders: a defeat for pharmacology?

Caraci, F., Kraneveld, A., Krzan, M. & Luca, M. D., Dec 15 2017, In : European Journal of Pharmacology. 817, p. 1

Research output: Contribution to journalArticle

Searching for new pharmacological targets for the treatment of Alzheimer's disease in Down syndrome

Caraci, F., Iulita, M. F., Pentz, R., Flores Aguilar, L., Orciani, C., Barone, C., Romano, C., Drago, F. & Cuello, A. C., 2017, (Accepted/In press) In : European Journal of Pharmacology.

Research output: Contribution to journalArticle

Topical ocular delivery of TGF-β1 to the back of the eye: Implications in age-related neurodegenerative diseases

Platania, C. B. M., Fisichella, V., Fidilio, A., Geraci, F., Lazzara, F., Leggio, G. M., Salomone, S., Drago, F., Pignatello, R., Caraci, F. & Bucolo, C., Oct 1 2017, In : International Journal of Molecular Sciences. 18, 10, 2076.

Research output: Contribution to journalArticle

Open Access
File
8 Downloads (Pure)
2016

A link between nerve growth factor metabolic deregulation and amyloid-β-driven inflammation in down syndrome

Iulita, M. F., Caraci, F. & Cuello, A. C., May 1 2016, In : CNS and Neurological Disorders - Drug Targets. 15, 4, p. 434-447 14 p.

Research output: Contribution to journalArticle

An inflammatory and trophic disconnect biomarker profile revealed in Down syndrome plasma: Relation to cognitive decline and longitudinal evaluation

Iulita, M. F., Ower, A., Barone, C., Pentz, R., Gubert, P., Romano, C., Cantarella, R. A., Elia, F., Buono, S., Recupero, M., Castellano, S., Bosco, P., Di Nuovo, S., Drago, F., Caraci, F. & Cuello, A. C., Nov 1 2016, In : Alzheimer's and Dementia. 12, 11, p. 1132-1148 17 p.

Research output: Contribution to journalArticle

Fluoxetine Prevents Aβ1-42-Induced Toxicity via a Paracrine Signaling Mediated by Transforming-Growth-Factor-β1

Caraci, F., Tascedda, F., Merlo, S., Benatti, C., Spampinato, S. F., Munafò, A., Leggio, G. M., Brunello, N., Drago, F., Sortino, M. A. & Copani, A., 2016, In : Frontiers in Pharmacology. 7, p. 389

Research output: Contribution to journalArticle

Italian psychiatrists perception on cognitive symptoms in major depressive disorder

Albert, U., Brugnoli, R., Caraci, F., Di Sciascio, G., Tortorella, A., Vampini, C., Cataldo, N. & Pegoraro, V., Jan 2 2016, In : International Journal of Psychiatry in Clinical Practice. 20, 1, p. 2-9 8 p.

Research output: Contribution to journalArticle

Italian psychiatrists perception on cognitive symptoms in major depressive disorder

Albert, U. S., Brugnoli, R., Caraci, F., Dell'Osso, B., Di Sciascio, G., Tortorella, A., Vampini, C., Cataldo, N. & Pegoraro, V., 2016, In : International Journal of Psychiatry in Clinical Practice. 20, 1, p. 2-9 8 p.

Research output: Contribution to journalArticle

Linkage of CNS and immunology with psychology: Searching for new pharmacological targets

Caraci, F. & Kamal, M. A., May 1 2016, In : CNS and Neurological Disorders - Drug Targets. 15, 4, p. 378-380 3 p.

Research output: Contribution to journalArticle

Polyamine Conjugation as a Promising Strategy To Target Amyloid Aggregation in the Framework of Alzheimer's Disease

Simoni, E., Caporaso, R., Bergamini, C., Fiori, J., Fato, R., Miszta, P., Filipek, S., Caraci, F., Giuffrida, M. L., Andrisano, V., Minarini, A., Bartolini, M. & Rosini, M., Dec 8 2016, In : ACS Medicinal Chemistry Letters. 7, 12, p. 1145-1150 6 p.

Research output: Contribution to journalArticle

Selective Serotonin Reuptake Inhibitors and Serotonin and Noradrenaline Reuptake Inhibitors Improve Cognitive Function in Partial Responders Depressed Patients: Results from a Prospective Observational Cohort Study

Castellano, S., Ventimiglia, A., Salomone, S., Ventimiglia, A., De Vivo, S., Signorelli, M. S., Bellelli, E., Santagati, M., Cantarella, R. A., Fazio, E., Aguglia, E., Drago, F., Di Nuovo, S. & Caraci, F., 2016, In : CNS and Neurological Disorders - Drug Targets. 15, 10, p. 1290-1298 9 p.

Research output: Contribution to journalArticle

TGF-β1 prevents rat retinal insult induced by amyloid-β (1–42) oligomers

Fisichella, V., Giurdanella, G., Platania, C. B. M., Romano, G. L., Leggio, G. M., Salomone, S., Drago, F., Caraci, F. & Bucolo, C., 2016, In : European Journal of Pharmacology. 787, p. 72-77 6 p.

Research output: Contribution to journalArticle

The antineoplastic drug flavopiridol reverses memory impairment induced by Amyloid-ß1-42 oligomers in mice

Leggio, G. M., Catania, M. V., Puzzo, D., Spatuzza, M., Pellitteri, R., Gulisano, W., Torrisi, S. A., Giurdanella, G., Piazza, C., Impellizzeri, A. R., Gozzo, L., Navarria, A., Bucolo, C., Nicoletti, F., Palmeri, A., Salomone, S., Copani, A., Caraci, F. & Drago, F., Apr 1 2016, In : Pharmacological Research. 106, p. 10-20 11 p.

Research output: Contribution to journalArticle

The antineoplastic drug flavopiridol reverses memory impairment induced by Amyloid-ß1-42 oligomers in mice

Leggio, G. M., Catania, M. V., Puzzo, D., Spatuzza, M., Pellitteri, R., Gulisano, W., Torrisi, S. A., Giurdanella, G., Piazza, C., Impellizzeri, A. R., Gozzo, L., Navarria, A., Bucolo, C., Palmeri, A., Salomone, S., Copani, A., Caraci, F. & Drago, F., Apr 1 2016, In : Pharmacological Research. 106, p. 10-20 11 p.

Research output: Contribution to journalArticle

2015

A key role for TGF-β1 in hippocampal synaptic plasticity and memory

Caraci, F., Gulisano, W., Guida, C. A., Impellizzeri, A. A. R., Drago, F., Puzzo, D. & Palmeri, A., Jun 10 2015, In : Scientific Reports. 5, 11252.

Research output: Contribution to journalArticle

Central serotonin2B receptor blockade inhibits cocaine-induced hyperlocomotion independently of changes of subcortical dopamine outflow

Devroye, C., Cathala, A., Di Marco, B., Caraci, F., Drago, F., Piazza, P. V. & Spampinato, U., Oct 1 2015, In : Neuropharmacology. 97, p. 329-337 9 p.

Research output: Contribution to journalArticle

Does Mood Disorder Questionnaire identify sub-threshold bipolarity? Evidence studying worsening of quality of life

Carta, M. G., Norcini-Pala, A., Moro, M. F., Balestrieri, M., Caraci, F., Dell'Osso, L., Sciascio, G. D., Faravelli, C., Hardoy, M. C., Aguglia, E., Roncone, R., Nardi, A. E. & Drago, F., Sep 1 2015, In : Journal of Affective Disorders. 183, p. 173-178 6 p., 7435.

Research output: Contribution to journalArticle

Dopamine D3 receptor-dependent changes in alpha6 GABAA subunit expression in striatum modulate anxiety-like behaviour: Responsiveness and tolerance to diazepam

Leggio, G. M., Torrisi, S. A., Castorina, A., Platania, C. B. M., Impellizzeri, A. A. R., Fidilio, A., Caraci, F., Bucolo, C., Drago, F. & Salomone, S., Sep 1 2015, In : European Neuropsychopharmacology. 25, 9, p. 1427-1436 10 p.

Research output: Contribution to journalArticle

Folate status in type 2 diabetic patients with and without retinopathy

Malaguarnera, G., Gagliano, C., Salomone, S., Giordano, M., Bucolo, C., Pappalardo, A., Drago, F., Caraci, F., Avitabile, T. & Motta, M., Aug 7 2015, In : Clinical Ophthalmology. 9, p. 1437-1442 6 p.

Research output: Contribution to journalArticle

Monomeric ß-amyloid interacts with type-1 insulin-like growth factor receptors to provide energy supply to neurons

Giuffrida, M. L., Tomasello, M. F., Pandini, G., Caraci, F., Battaglia, G., Busceti, C., Di Pietro, P., Pappalardo, G., Attanasio, F., Chiechio, S., Bagnoli, S., Nacmias, B., Sorbi, S., Vigneri, R., Rizzarelli, E., Nicoletti, F. & Copani, A., Aug 7 2015, In : Frontiers in Cellular Neuroscience. 9, AUGUST, 297.

Research output: Contribution to journalArticle

Multi-modality as a new pharmacological approach for treatment of depression: The role of vortioxetine

Caraci, F. & Di Sciascio, G., Jun 1 2015, In : Italian Journal of Psychopathology. 21, 2, p. 210-223 14 p.

Research output: Contribution to journalArticle

Neuroprotective effects of the monoamine oxidase inhibitor tranylcypromine and its amide derivatives against Aβ(1-42)-induced toxicity

Caraci, F., Pappalardo, G., Basile, L., Giuffrida, A., Copani, A., Tosto, R., Sinopoli, A., Giuffrida, M. L., Pirrone, E., Drago, F., Pignatello, R. & Guccione, S., Jul 18 2015, In : European Journal of Pharmacology. 764, p. 256-263 8 p., 70113.

Research output: Contribution to journalArticle

Silybin-vitamin E-phospholipids complex reduces liver fibrosis in patients with chronic hepatitis C treated with pegylated interferon α and ribavirin

Malaguarnera, M., Motta, M., Vacante, M., Malaguarnera, G., Caraci, F., Nunnari, G., Gagliano, C., Greco, C., Chisari, G., Drago, F. & Bertino, G., 2015, In : American Journal of Translational Research. 7, 11, p. 2510-2518 9 p.

Research output: Contribution to journalArticle

The attributable burden of panic disorder in the impairment of quality of life in a national survey in Italy

Carta, M. G., Moro, M. F., Aguglia, E., Balestrieri, M., Caraci, F., Dell'Osso, L., Di Sciascio, G., Drago, F., Hardoy, M. C., D'Aloja, E., Machado, S., Roncone, R. & Faravelli, C., Nov 1 2015, In : International Journal of Social Psychiatry. 61, 7, p. 693-699 7 p.

Research output: Contribution to journalArticle

2014

Acetyl-L-carnitine supplementation during HCV therapy with pegylated interferon-α 2b plus ribavirin: Effect on work performance; a randomized clinical trial

Malaguarnera, G., Pennisi, M., Gagliano, C., Vacante, M., Malaguarnera, M., Salomone, S., Drago, F., Bertino, G., Caraci, F., Nunnari, G. & Malaguarnera, M., May 5 2014, In : Hepatitis Monthly. 14, 5

Research output: Contribution to journalArticle