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2014

Eating disorders as a public health issue: Prevalence and attributable impairment of quality of life in an Italian community sample

Carta, M. G., Preti, A., Moro, M. F., Aguglia, E., Balestrieri, M., Caraci, F., Dell'Osso, L., Di Sciascio, G., Drago, F., Faravelli, C., Hardoy, M. C., D'Aloja, E., Cossu, G., Calò, S., Palumbo, G. & Bhugra, D., 2014, In : International Review of Psychiatry. 26, 4, p. 486-492 7 p.

Research output: Contribution to journalArticle

Homocysteine serum levels in diabetic patients with non proliferative, proliferative and without retinopathy

Malaguarnera, G., Gagliano, C., Giordano, M., Salomone, S., Vacante, M., Bucolo, C., Caraci, F., Reibaldi, M., Drago, F., Avitabile, T. & Motta, M., 2014, In : BioMed Research International. 2014, 191497.

Research output: Contribution to journalArticle

Levels of the Rab GDP dissociation inhibitor (GDI) are altered in the prenatal restrain stress mouse model of schizophrenia and are differentially regulated by the mGlu2/3 receptor agonists, LY379268 and LY354740

Orlando, R., Borro, M., Motolese, M., Molinaro, G., Scaccianoce, S., Caruso, A., Di Nuzzo, L., Caraci, F., Matrisciano, F., Pittaluga, A., Mairesse, J., Simmaco, M., Nisticò, R., Monn, J. A. & Nicoletti, F., 2014, In : Neuropharmacology. 86, p. 133-144 12 p.

Research output: Contribution to journalArticle

Omega-3 fatty acids and depression: Scientific evidence and biological mechanisms

Grosso, G., Galvano, F., Marventano, S., Malaguarnera, M., Bucolo, C., Drago, F. & Caraci, F., 2014, In : Oxidative Medicine and Cellular Longevity. 2014, 313570.

Research output: Contribution to journalArticle

Role of omega-3 fatty acids in the treatment of depressive disorders: A comprehensive meta-analysis of randomized clinical trials

Grosso, G., Pajak, A., Marventano, S., Castellano, S., Galvano, F., Bucolo, C., Drago, F. & Caraci, F., May 7 2014, In : PLoS One. 9, 5, e96905.

Research output: Contribution to journalArticle

Searching for disease-modifying drugs in AD: Can we combine neuropsychological tools with biological markers?

Caraci, F., Castellano, S., Salomone, S., Drago, F., Bosco, P. & Di Nuovo, S., 2014, In : CNS and Neurological Disorders - Drug Targets. 13, 1, p. 173-186 14 p.

Research output: Contribution to journalArticle

2013

Clinical pharmacology of novel anti-Alzheimer disease modifying medications

Caraci, F., Bosco, P., Leggio, G. M., Malaguarnera, M., Drago, F., Bucolo, C. & Salomone, S., 2013, In : Current Topics in Medicinal Chemistry. 13, 15, p. 1853-1863 11 p.

Research output: Contribution to journalArticle

Dopamine D3 receptor as a new pharmacological target for the treatment of depression

Leggio, G. M., Salomone, S., Bucolo, C., Platania, C., Micale, V., Caraci, F. & Drago, F., 2013, In : European Journal of Pharmacology. 719, 1-3, p. 25-33 9 p.

Research output: Contribution to journalArticle

Epigenetic drugs for Alzheimer's disease: Hopes and challenges

Caraci, F., Leggio, G. M., Drago, F. & Salomone, S., Apr 2013, In : British Journal of Clinical Pharmacology. 75, 4, p. 1154-1155 2 p.

Research output: Contribution to journalArticle

Erratum: Quality of Life and Urban / Rural Living: Preliminary Results of a Community Survey in Italy (Clinical Practice & Epidemiology in Mental Health (2012) 8 (169-174))

Carta, M. G., Aguglia, E., Caraci, F., Dell'Osso, L., Di Sciascio, G., Drago, F., Del Giudice, E., Faravelli, C., Hardoy, M. C., Lecca, M. E., Moro, M. F., Calò, S., Casacchia, M., Angermeyer, M. C. & Balestrieri, M., 2013, In : Clinical Practice and Epidemiology in Mental Health. 9, p. 148 1 p.

Research output: Contribution to journalArticle

Fingolimod protects cultured cortical neurons against excitotoxic death

Di Menna, L., Molinaro, G., Di Nuzzo, L., Riozzi, B., Zappulla, C., Pozzilli, C., Turrini, R., Caraci, F., Copani, A., Battaglia, G., Nicoletti, F. & Bruno, V., Jan 2013, In : Pharmacological Research. 67, 1, p. 1-9 9 p.

Research output: Contribution to journalArticle

Metal fume fever

Malaguarnera, M., Drago, F., Malaguarnera, G., Li Volti, G., Salomone, S., Caraci, F., Galvano, F., Vacante, M., Bucolo, C. & Malaguarnera, M., 2013, In : Lancet. 381, 9885, p. 2298 1 p.

Research output: Contribution to journalArticle

Pericentrin expression in Down's syndrome

Salemi, M., Barone, C., Romano, C., Salluzzo, R., Caraci, F., Cantarella, R. A., Salluzzo, M. G., Drago, F., Romano, C. & Bosco, P., Nov 2013, In : Neurological Sciences. 34, 11, p. 2023-2025 3 p.

Research output: Contribution to journalArticle

Role of the transforming-growth-factor-β1 gene in late-onset alzheimer's disease: Implications for the treatment

Bosco, P., Ferri, R., Salluzzo, M. G., Castellano, S., Signorelli, M., Nicoletti, F., Di Nuovo, S., Drago, F. & Caraci, F., 2013, In : Current Genomics. 14, 2, p. 147-156 10 p.

Research output: Contribution to journalArticle

2012

Beta-Amyloid monomer and insulin/IGF-1 signaling in Alzheimer's disease

Giuffrida, M. L., Tomasello, F., Caraci, F., Chiechio, S., Nicoletti, F. & Copani, A., 2012, In : Molecular Neurobiology. 46, 3, p. 605-613 9 p.

Research output: Contribution to journalArticle

Clinically significant drug interactions with newer antidepressants

Spina, E., Trifirò, G. & Caraci, F., 2012, In : CNS Drugs. 26, 1, p. 39-67 29 p.

Research output: Contribution to journalArticle

Dysfunction of TGF-β1 signaling in Alzheimer's disease: Perspectives for neuroprotection

Caraci, F., Spampinato, S., Sortino, M. A., Bosco, P., Battaglia, G., Bruno, V., Drago, F., Nicoletti, F. & Copani, A., Jan 2012, In : Cell & Tissue Research. 347, 1, p. 291-301 11 p.

Research output: Contribution to journalArticle

Estrogen receptors and type 1 metabotropic glutamate receptors are interdependent in protecting cortical neurons against β-amyloid toxicity

Spampinato, S. F., Molinaro, G., Merlo, S., Iacovelli, L., Caraci, F., Battaglia, G., Nicoletti, F., Bruno, V. & Sortino, M. A., Jan 2012, In : Molecular Pharmacology. 81, 1, p. 12-20 9 p.

Research output: Contribution to journalArticle

Expression of LDOC1 mRNA in leucocytes of patients with Down's syndrome

Salemi, M., Barone, C., Romano, C., Ridolfo, F., Salluzzo, R., Scillato, F., Scavuzzo, C., Caraci, F., Calogero, A. E., Romano, C. & Bosco, P., Apr 2012, In : Journal of Genetics. 91, 1, p. 95-98 4 p.

Research output: Contribution to journalArticle

Metabotropic glutamate receptors in neurodegeneration/neuroprotection: Still a hot topic?

Caraci, F., Battaglia, G., Sortino, M. A., Spampinato, S., Molinaro, G., Copani, A., Nicoletti, F. & Bruno, V., Sep 2012, In : Neurochemistry International. 61, 4, p. 559-565 7 p.

Research output: Contribution to journalArticle

New pharmacological strategies for treatment of Alzheimer's disease: Focus on disease modifying drugs

Salomone, S., Caraci, F., Leggio, G. M., Fedotova, J. & Drago, F., Apr 2012, In : British Journal of Clinical Pharmacology. 73, 4, p. 504-517 14 p.

Research output: Contribution to journalArticle

Quality of life and urban / rural living: Preliminary results of a community survey in Italy

Carta, M. G., Aguglia, E., Caraci, F., Dell'Osso, L., Di Sciascio, G., Drago, F., Del Giudice, E., Faravelli, C., Hardoy, M. C., Lecca, M. E., Moro, M. F., Calò, S., Casacchia, M., Angermeyer, M. & Balestrieri, M., 2012, In : Clinical Practice and Epidemiology in Mental Health. 8, p. 169-174 6 p.

Research output: Contribution to journalArticle

The CC genotype of transforming growth factor-β1 increases the risk of late-onset Alzheimer's disease and is associated with AD-related depression

Caraci, F., Bosco, P., Signorelli, M., Spada, R. S., Cosentino, F. I., Toscano, G., Bonforte, C., Muratore, S., Prestianni, G., Panerai, S., Giambirtone, M. C., Gulotta, E., Romano, C., Salluzzo, M. G., Nicoletti, F., Copani, A., Drago, F., Aguglia, E. & Ferri, R., Apr 2012, In : European Neuropsychopharmacology. 22, 4, p. 281-289 9 p.

Research output: Contribution to journalArticle

The lifetime prevalence of bipolar disorders and the use of antidepressant drugs in bipolar depression in Italy

Carta, M. G., Aguglia, E., Balestrieri, M., Calabrese, J. R., Caraci, F., Dell'Osso, L., Di Sciascio, G., Drago, F., Faravelli, C., Lecca, M. E., Moro, M. F., Nardini, M., Palumbo, G. & Hardoy, M. C., Feb 2012, In : Journal of Affective Disorders. 136, 3, p. 775-780 6 p.

Research output: Contribution to journalArticle

2011

Differential expression of PARP1 mRNA in leucocytes of patients with Down's syndrome

Salemi, M., Barone, C., Romano, C., Ridolfo, F., Gulotta, E., Scavuzzo, C., Salluzzo, M. G., Giambirtone, M., Caraci, F., Romano, C. & Bosco, P., Dec 2011, In : Journal of Genetics. 90, 3, p. 469-472 4 p.

Research output: Contribution to journalArticle

Induction of the Wnt antagonist dickkopf-1 is involved in stress-induced hippocampal damage

Matrisciano, F., Busceti, C. L., Bucci, D., Orlando, R., Caruso, A., Molinaro, G., Cappuccio, I., Riozzi, B., Gradini, R., Motolese, M., Caraci, F., Copani, A., Scaccianoce, S., Melchiorri, D., Bruno, V., Battaglia, G. & Nicoletti, F., 2011, In : PLoS One. 6, 1, e16447.

Research output: Contribution to journalArticle

Inhibition of PI3K prevents the proliferation and differentiation of human lung fibroblasts into myofibroblasts: The role of class I P110 isoforms

Conte, E., Fruciano, M., Fagone, E., Gili, E., Caraci, F., Iemmolo, M., Crimi, N. & Vancheri, C., Oct 3 2011, In : PLoS One. 6, 10, e24663.

Research output: Contribution to journalArticle

Metabolic drug interactions between antidepressants and anticancer drugs: Focus on selective serotonin reuptake inhibitors and hypericum extract

Caraci, F., Crupi, R., Drago, F. & Spina, E., Jul 2011, In : Current Drug Metabolism. 12, 6, p. 570-577 8 p.

Research output: Contribution to journalArticle

Neurotoxic properties of the anabolic androgenic steroids nandrolone and methandrostenolone in primary neuronal cultures

Caraci, F., Pistarà, V., Corsaro, A., Tomasello, F., Giuffrida, M. L., Sortino, M. A., Nicoletti, F. & Copani, A., Apr 2011, In : Journal of Neuroscience Research. 89, 4, p. 592-600 9 p.

Research output: Contribution to journalArticle

Sub-threshold depression and antidepressants use in a community sample: Searching anxiety and finding bipolar disorder

Carta, M. G., Tondo, L., Balestrieri, M., Caraci, F., Dell'Osso, L., Di Sciascio, G., Faravelli, C., Hardoy, M. C., Lecca, M. E., Moro, M. F., Bhat, K. M., Casacchia, M. & Drago, F., Oct 10 2011, In : BMC Psychiatry. 11, 164.

Research output: Contribution to journalArticle

Targeting group II Metabotropic Glutamate (mGlu) receptors for the treatment of psychosis associated with alzheimer's disease: Selective activation of mGlu2 receptors amplifies β-amyloid toxicity in cultured neurons, whereas dual activation of mGlu2 and mGlu3 receptors is neuroprotective

Caraci, F., Molinaro, G., Battaglia, G., Giuffrida, M. L., Riozzi, B., Traficante, A., Bruno, V., Cannella, M., Merlo, S., Wang, X., Heinz, B. A., Nisenbaum, E. S., Britton, T. C., Drago, F., Sortino, M. A., Copani, A. & Nicoletti, F., Mar 2011, In : Molecular Pharmacology. 79, 3, p. 618-626 9 p.

Research output: Contribution to journalArticle

TGF-β1 pathway as a new target for neuroprotection in alzheimer's disease

Caraci, F., Battaglia, G., Bruno, V., Bosco, P., Carbonaro, V., Giuffrida, M. L., Drago, F., Sortino, M. A., Nicoletti, F. & Copani, A., Aug 2011, In : CNS Neuroscience and Therapeutics. 17, 4, p. 237-249 13 p.

Research output: Contribution to journalArticle

2010

Depression and Alzheimer's disease: Neurobiological links and common pharmacological targets

Caraci, F., Copani, A., Nicoletti, F. & Drago, F., Jan 10 2010, In : European Journal of Pharmacology. 626, 1, p. 64-71 8 p.

Research output: Contribution to journalArticle

Efficacy and tolerability of Hypericum extract for the treatment of mild to moderate depression

Kasper, S., Caraci, F., Forti, B., Drago, F. & Aguglia, E., Nov 2010, In : European Neuropsychopharmacology. 20, 11, p. 747-765 19 p.

Research output: Contribution to journalArticle

The monomer state of beta-amyloid: where the Alzheimer's disease protein meets physiology.

Giuffrida, M. L., Caraci, F., De Bona, P., Pappalardo, G., Nicoletti, F., Rizzarelli, E. & Copani, A., 2010, In : Reviews in the Neurosciences. 21, 2, p. 83-93 11 p.

Research output: Contribution to journalArticle

The use of antidepressant drugs and the lifetime prevalence of major depressive disorders in italy

Carta, M. G., Aguglia, E., Bocchetta, A., Balestrieri, M., Caraci, F., Casacchia, M., Dell'Osso, L., Di Sciascio, G., Drago, F., Faravelli, C., Lecca, M. E., Moro, M. F., Morosini, P. L., Nardini, M., Palumbo, G. & Hardoy, M. C., 2010, In : Clinical Practice and Epidemiology in Mental Health. 6, p. 94-100 7 p.

Research output: Contribution to journalArticle

2009

Design and synthesis of new trehalose-conjugated pentapeptides as inhibitors of Aβ(1-42) fibrillogenesis and toxicity

De Bona, P., Giuffrida, M. L., Caraci, F., Copani, A., Pignataro, B., Attanasio, F., Cataldo, S., Pappalardo, G. & Rizzarelli, E., 2009, In : Journal of Peptide Science. 15, 3, p. 220-228 9 p.

Research output: Contribution to journalArticle

Enhanced expression of ERα in astrocytes modifies the response of cortical neurons to β-amyloid toxicity

Carbonaro, V., Caraci, F., Giuffrida, M. L., Merlo, S., Canonico, P. L., Drago, F., Copani, A. & Sortino, M. A., Mar 2009, In : Neurobiology of Disease. 33, 3, p. 415-421 7 p.

Research output: Contribution to journalArticle

Pregabalin in the treatment of chronic pain: An overview

Chiechio, S., Zammataro, M., Caraci, F., Rampello, L., Copani, A., Sabato, A. F. & Nicoletti, F., 2009, In : Clinical Drug Investigation. 29, 3, p. 203-213 11 p.

Research output: Contribution to journalArticle

SPANX-B and SPANX-C (Xq27 region) gene dosage analysis in down's syndrome subjects with undescended testes

Salemi, M., Romano, C., Barone, C., Calí, F., Caraci, F., Romano, C., Scavuzzo, C., Scillato, F., Salluzzo, M. G., Piccione, M., Martines, M., Corsello, G., Nicoletti, F. & Bosco, P., Apr 2009, In : Journal of Genetics. 88, 1, p. 93-97 5 p.

Research output: Contribution to journalArticle

β-amyloid monomers are neuroprotective

Giuffrida, M. L., Caraci, F., Pignataro, B., Cataldo, S., De Bona, P., Bruno, V., Molinaro, G., Pappalardo, G., Messina, A., Palmigiano, A., Garozzo, D., Nicoletti, F., Rizzarelli, E. & Copani, A., Aug 26 2009, In : Journal of Neuroscience. 29, 34, p. 10582-10587 6 p.

Research output: Contribution to journalArticle

2008

TGF-β1 protects against Aβ-neurotoxicity via the phosphatidylinositol-3-kinase pathway

Caraci, F., Battaglia, G., Busceti, C., Biagioni, F., Mastroiacovo, F., Bosco, P., Drago, F., Nicoletti, F., Sortino, M. A. & Copani, A., May 2008, In : Neurobiology of Disease. 30, 2, p. 234-242 9 p.

Research output: Contribution to journalArticle

TGF-β1 targets the GSK-3β/β-catenin pathway via ERK activation in the transition of human lung fibroblasts into myofibroblasts

Caraci, F., Gili, E., Calafiore, M., Failla, M., La Rosa, C., Crimi, N., Sortino, M. A., Nicoletti, F., Copani, A. & Vancheri, C., Apr 2008, In : Pharmacological Research. 57, 4, p. 274-282 9 p.

Research output: Contribution to journalArticle

The APOE ε4 allele increases the risk of impaired spatial working memory in obstructive sleep apnea

Cosentino, F. I. I., Bosco, P., Drago, V., Prestianni, G., Lanuzza, B., Iero, I., Tripodi, M., Spada, R. S., Toscano, G., Caraci, F. & Ferri, R., Dec 2008, In : Sleep Medicine. 9, 8, p. 831-839 9 p.

Research output: Contribution to journalArticle

The cell cycle molecules behind neurodegeneration in Alzheimer's disease: Perspectives for drug development

Copani, A., Guccione, S., Giurato, L., Caraci, F., Calafiore, M., Sortino, M. A. & Nicoletti, F., 2008, In : Current Medicinal Chemistry. 15, 24, p. 2420-2432 13 p.

Research output: Contribution to journalArticle

The Wnt antagonist, Dickkopf-1, as a target for the treatment of neurodegenerative disorders

Caraci, F., Busceti, C., Biagioni, F., Aronica, E., Mastroiacovo, F., Cappuccio, I., Battaglia, G., Bruno, V., Caricasole, A., Copani, A. & Nicoletti, F., Dec 2008, In : Neurochemical Research. 33, 12, p. 2401-2406 6 p.

Research output: Contribution to journalArticle

2007

A new 6-bp SOX-3 polyalanine tract deletion does not segregate with mental retardation

Salemi, M., Romano, C., Ragusa, L., Di Vita, G., Salluzzo, R., Oteri, I., Trovato, M. L., Romano, C., Caraci, F., Nicoletti, F. & Bosco, P., Jun 2007, In : Genetic Testing. 11, 2, p. 124-127 4 p.

Research output: Contribution to journalArticle

The CDC2 I-G-T haplotype associated with the APOE ε4 allele increases the risk of sporadic Alzheimer's disease in Sicily

Bosco, P., Caraci, F., Copani, A., Spada, R. S., Sortino, M. A., Salluzzo, R., Salemi, M., Nicoletti, F. & Ferri, R., Jun 4 2007, In : Neuroscience Letters. 419, 3, p. 195-198 4 p.

Research output: Contribution to journalArticle

The nature of the cell cycle in neurons: Focus on a "non-canonical" pathway of DNA replication causally related to death

Copani, A., Caraci, F., Hoozemans, J. J. M., Calafiore, M., Angela Sortino, M. & Nicoletti, F., Apr 2007, In : Biochimica et Biophysica Acta - Molecular Basis of Disease. 1772, 4, p. 409-412 4 p.

Research output: Contribution to journalArticle