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Research Output 1984 2020

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2020

Is there an interplay between immune checkpoint inhibitors, thromboprophylactic treatments and thromboembolic events? Mechanisms and impact in non-small cell lung cancer patients

Nichetti, F., Ligorio, F., Zattarin, E., Signorelli, D., Prelaj, A., Proto, C., Galli, G., Marra, A., Apollonio, G., Porcu, L., de Braud, F., Lo Russo, G., Ferrara, R. & Garassino, M. C., Jan 2020, In : Cancers. 12, 1, 67.

Research output: Contribution to journalArticle

Open Access
Non-Small Cell Lung Carcinoma
Platelet Aggregation Inhibitors
Therapeutics
Atherosclerotic Plaques
Anticoagulants
2019
Artificial Intelligence
Melanoma
L-Lactate Dehydrogenase
Neutrophils
Lymphocytes

Assessment of Ramucirumab plus paclitaxel as switch maintenance versus continuation of first-line chemotherapy in patients with advanced HER-2 negative gastric or gastroesophageal junction cancers: The ARMANI phase III trial

Di Bartolomeo, M., Niger, M., Morano, F., Corallo, S., Antista, M., Tamberi, S., Lonardi, S., Di Donato, S., Berardi, R., Scartozzi, M., Cardellino, G. G., Di Costanzo, F., Rimassa, L., Luporini, A. G., Longarini, R., Zaniboni, A., Bertolini, A., Tomasello, G., Pinotti, G., Scagliotti, G. & 19 others, Tortora, G., Bonetti, A., Spallanzani, A., Frassineti, G. L., Tassinari, D., Giuliani, F., Cinieri, S., Maiello, E., Verusio, C., Bracarda, S., Catalano, V., Basso, M., Ciuffreda, L., De Vita, F., Parra, H. S., Fornaro, L., Caporale, M., De Braud, F. & Pietrantonio, F., Mar 29 2019, In : BMC Cancer. 19, 1, 283.

Research output: Contribution to journalArticle

Esophagogastric Junction
Paclitaxel
Stomach
Maintenance
Drug Therapy

Assessment of Ramucirumab plus paclitaxel as switch maintenance versus continuation of first-line chemotherapy in patients with advanced HER-2 negative gastric or gastroesophageal junction cancers: The ARMANI phase III trial

Di Bartolomeo, M., Niger, M., Morano, F., Corallo, S., Antista, M., Tamberi, S., Lonardi, S., Di Donato, S., Berardi, R., Scartozzi, M., Cardellino, G. G., Di Costanzo, F., Rimassa, L., Luporini, A. G., Longarini, R., Zaniboni, A., Bertolini, A., Tomasello, G., Pinotti, G., Scagliotti, G. & 19 others, Tortora, G., Bonetti, A., Spallanzani, A., Frassineti, G. L., Tassinari, D., Giuliani, F., Cinieri, S., Maiello, E., Verusio, C., Bracarda, S., Catalano, V., Basso, M., Ciuffreda, L., De Vita, F., Parra, H. S., Fornaro, L., Caporale, M., De Braud, F. & Pietrantonio, F., Mar 29 2019, In : BMC Cancer. 19, 1, 283.

Research output: Contribution to journalArticle

Esophagogastric Junction
Paclitaxel
Stomach
Maintenance
Drug Therapy

Assessment of Ramucirumab plus paclitaxel as switch maintenance versus continuation of first-line chemotherapy in patients with advanced HER-2 negative gastric or gastroesophageal junction cancers: The ARMANI phase III trial

Di Bartolomeo, M., Niger, M., Morano, F., Corallo, S., Antista, M., Tamberi, S., Lonardi, S., Di Donato, S., Berardi, R., Scartozzi, M., Cardellino, G. G., Di Costanzo, F., Rimassa, L., Luporini, A. G., Longarini, R., Zaniboni, A., Bertolini, A., Tomasello, G., Pinotti, G., Scagliotti, G. & 19 others, Tortora, G., Bonetti, A., Spallanzani, A., Frassineti, G. L., Tassinari, D., Giuliani, F., Cinieri, S., Maiello, E., Verusio, C., Bracarda, S., Catalano, V., Basso, M., Ciuffreda, L., De Vita, F., Parra, H. S., Fornaro, L., Caporale, M., De Braud, F. & Pietrantonio, F., Mar 29 2019, In : BMC Cancer. 19, 1, p. 1-9 9 p.

Research output: Contribution to journalArticle

Esophagogastric Junction
Paclitaxel
Stomach
Maintenance
Drug Therapy

Association between antibiotic-immunotherapy exposure ratio and outcome in metastatic non small cell lung cancer

Galli, G., Triulzi, T., Proto, C., Signorelli, D., Imbimbo, M., Poggi, M., Fucà, G., Ganzinelli, M., Vitali, M., Palmieri, D., Tessari, A., de Braud, F., Garassino, M. C., Colombo, M. P. & Lo Russo, G., Jun 2019, In : Lung Cancer. 132, p. 72-78 7 p.

Research output: Contribution to journalArticle

Non-Small Cell Lung Carcinoma
Immunotherapy
Anti-Bacterial Agents
Disease-Free Survival
Survival

Capecitabine and Temozolomide versus FOLFIRI in RAS-Mutated, MGMT-Methylated Metastatic Colorectal Cancer

Pietrantonio, F., Lobefaro, R., Antista, M., Lonardi, S., Raimondi, A., Morano, F., Mosconi, S., Rimassa, L., Murgioni, S., Sartore-Bianchi, A., Tomasello, G., Longarini, R., Farina, G., Petrelli, F., Gori, S., Randon, G., Corallo, S., Pagani, F., Guarini, V., Palermo, F. & 11 others, Martinetti, A., Macagno, M., Barault, L., Perrone, F., Tamborini, E., Milione, M., Di Nicolantonio, F., Di Maio, M., Fucà, G., Di Bartolomeo, M. & de Braud, F., Nov 18 2019, In : Clin. Cancer Res..

Research output: Contribution to journalArticle

temozolomide
Guanine
Methyltransferases
Colorectal Neoplasms
Disease-Free Survival

Capecitabine and Temozolomide versus FOLFIRI in RAS-Mutated, MGMT-Methylated Metastatic Colorectal Cancer

Pietrantonio, F., Lobefaro, R., Antista, M., Lonardi, S., Raimondi, A., Morano, F., Mosconi, S., Rimassa, L., Murgioni, S., Sartore-Bianchi, A., Tomasello, G., Longarini, R., Farina, G., Petrelli, F., Gori, S., Randon, G., Corallo, S., Pagani, F., Guarini, V., Palermo, F. & 11 others, Martinetti, A., Macagno, M., Barault, L., Perrone, F., Tamborini, E., Milione, M., Di Nicolantonio, F., Di Maio, M., Fucà, G., Di Bartolomeo, M. & de Braud, F., Nov 18 2019, In : Clin. Cancer Res.. p. 1-27 27 p.

Research output: Contribution to journalArticle

temozolomide
Guanine
Methyltransferases
Colorectal Neoplasms
Disease-Free Survival

Characterization of patients with metastatic non-small-cell lung cancer obtaining long-term benefit from immunotherapy

Galli, G., Proto, C., Signorelli, D., Imbimbo, M., Ferrara, R., Prelaj, A., De Toma, A., Ganzinelli, M., Zilembo, N., De Braud, F., Garassino, M. C. & Lo Russo, G., Aug 2019, In : Future Oncology. 15, 23, p. 2743-2757 15 p.

Research output: Contribution to journalArticle

Non-Small Cell Lung Carcinoma
Immunotherapy
Multivariate Analysis
Open Access
L-Lactate Dehydrogenase
Monoclonal Antibodies
CD274 Antigen
Area Under Curve
Neoplasms

Combination of Immunotherapy and Brain Radiotherapy in Metastatic Melanoma: A Retrospective Analysis

Galli, G., Cavalieri, S., Di Guardo, L., Cimminiello, C., Nichetti, F., Corti, F., Garcia, M. A., Pappalardi, B., Fallai, C., De Braud, F., Platania, M. & Del Vecchio, M., Apr 1 2019, In : Oncology Research and Treatment. 42, 4, p. 182-188 7 p.

Research output: Contribution to journalArticle

Immunotherapy
Melanoma
Radiotherapy
Brain
Survival

Comparative effectiveness of gemcitabine plus nab-paclitaxel and folfirinox in the first-line setting of metastatic pancreatic cancer: A systematic review and meta-analysis

Pusceddu, S., Ghidini, M., Torchio, M., Corti, F., Tomasello, G., Niger, M., Prinzi, N., Nichetti, F., Coinu, A., Bartolomeo, M. D., Cabiddu, M., Passalacqua, R., De Braud, F. & Petrelli, F., Apr 2019, In : Cancers. 11, 4, 484.

Research output: Contribution to journalArticle

Open Access
gemcitabine
Pancreatic Neoplasms
Meta-Analysis
Febrile Neutropenia
oxaliplatin

Derazantinib (ARQ 087) in advanced or inoperable FGFR2 gene fusion-positive intrahepatic cholangiocarcinoma

Mazzaferro, V., El-Rayes, B. F., Droz Dit Busset, M., Cotsoglou, C., Harris, W. P., Damjanov, N., Masi, G., Rimassa, L., Personeni, N., Braiteh, F., Zagonel, V., Papadopoulos, K. P., Hall, T., Wang, Y., Schwartz, B., Kazakin, J., Bhoori, S., de Braud, F. & Shaib, W. L., Jan 2019, In : British Journal of Cancer. 120, 2, p. 165-171 7 p.

Research output: Contribution to journalArticle

Receptor, Fibroblast Growth Factor, Type 2
Cholangiocarcinoma
Gene Fusion
Asthenopia
Hyperphosphatemia

Derazantinib (ARQ 087) in advanced or inoperable FGFR2 gene fusion-positive intrahepatic cholangiocarcinoma

Mazzaferro, V., El-Rayes, B. F., Droz dit Busset, M., Cotsoglou, C., Harris, W. P., Damjanov, N., Masi, G., Rimassa, L., Personeni, N., Braiteh, F., Zagonel, V., Papadopoulos, K. P., Hall, T., Wang, Y., Schwartz, B., Kazakin, J., Bhoori, S., de Braud, F. & Shaib, W. L., 2019, In : British Journal of Cancer. 120, 2, p. 165-171 7 p.

Research output: Contribution to journalArticle

Developing a score system to predict therapeutic outcomes to anti-PD-1 immunotherapy in metastatic melanoma

Indini, A., Di Guardo, L., Cimminiello, C., Prisciandaro, M., Randon, G., De Braud, F. & Del Vecchio, M., Jan 1 2019, (Accepted/In press) In : Tumori.

Research output: Contribution to journalArticle

Immunotherapy
Melanoma
Lymphocyte Count
L-Lactate Dehydrogenase
Survival

DPYD*6 plays an important role in fluoropyrimidine toxicity in addition to DPYD*2A and c.2846A>T: a comprehensive analysis in 1254 patients

Del Re, M., Cinieri, S., Michelucci, A., Salvadori, S., Loupakis, F., Schirripa, M., Cremolini, C., Crucitta, S., Barbara, C., Di Leo, A., Latiano, T. P., Pietrantonio, F., Di Donato, S., Simi, P., Passardi, A., De Braud, F., Altavilla, G., Zamagni, C., Bordonaro, R., Butera, A. & 6 others, Maiello, E., Pinto, C., Falcone, A., Mazzotti, V., Morganti, R. & Danesi, R., Jan 1 2019, In : Pharmacogenomics Journal.

Research output: Contribution to journalArticle

Dihydrouracil Dehydrogenase (NADP)
Drug-Related Side Effects and Adverse Reactions
Neutropenia
Real-Time Polymerase Chain Reaction

DPYD*6 plays an important role in fluoropyrimidine toxicity in addition to DPYD*2A and c.2846A>T: a comprehensive analysis in 1254 patients

Del Re, M., Cinieri, S., Michelucci, A., Salvadori, S., Loupakis, F., Schirripa, M., Cremolini, C., Crucitta, S., Barbara, C., Di Leo, A., Latiano, T. P., Pietrantonio, F., Di Donato, S., Simi, P., Passardi, A., De Braud, F., Altavilla, G., Zamagni, C., Bordonaro, R., Butera, A. & 6 others, Maiello, E., Pinto, C., Falcone, A., Mazzotti, V., Morganti, R. & Danesi, R., Dec 2019, In : Pharmacogenomics Journal. 19, 6, p. 556-563 8 p.

Research output: Contribution to journalArticle

Dihydrouracil Dehydrogenase (NADP)
Drug-Related Side Effects and Adverse Reactions
Neutropenia
Real-Time Polymerase Chain Reaction

DPYD*6 plays an important role in fluoropyrimidine toxicity in addition to DPYD*2A and c.2846A>T: a comprehensive analysis in 1254 patients

Del Re, M., Cinieri, S., Michelucci, A., Salvadori, S., Loupakis, F., Schirripa, M., Cremolini, C., Crucitta, S., Barbara, C., Di Leo, A., Latiano, T. P., Pietrantonio, F., Di Donato, S., Simi, P., Passardi, A., De Braud, F., Altavilla, G., Zamagni, C., Bordonaro, R., Butera, A. & 6 others, Maiello, E., Pinto, C., Falcone, A., Mazzotti, V., Morganti, R. & Danesi, R., Dec 2019, In : Pharmacogenomics Journal. 19, 6, p. 556-563 8 p.

Research output: Contribution to journalArticle

Dihydrouracil Dehydrogenase (NADP)
Drug-Related Side Effects and Adverse Reactions
Neutropenia
Real-Time Polymerase Chain Reaction

Efficacy and safety of immunotherapy in elderly patients with non-small cell lung cancer

Galli, G., De Toma, A., Pagani, F., Randon, G., Trevisan, B., Prelaj, A., Ferrara, R., Proto, C., Signorelli, D., Ganzinelli, M., Zilembo, N., de Braud, F., Garassino, M. C. & Lo Russo, G., Nov 2019, In : Lung Cancer. 137, p. 38-42 5 p.

Research output: Contribution to journalArticle

Non-Small Cell Lung Carcinoma
Immunotherapy
Safety
Disease-Free Survival
Survival

Epsilon: A prognostic score for immunotherapy in advanced non-small-cell lung cancer: A validation cohort

Prelaj, A., Ferrara, R., Rebuzzi, S. E., Proto, C., Signorelli, D., Galli, G., De Toma, A., Randon, G., Pagani, F., Viscardi, G., Brambilla, M., Trevisan, B., Ganzinelli, M., Martinetti, A., Gallucci, R., Di Mauro, R. M., Molino, G., Zilembo, N., Torri, V., de Braud, F. M. & 2 others, Garassino, M. C. & Lo Russo, G., Dec 2019, In : Cancers. 11, 12, 1954.

Research output: Contribution to journalArticle

Open Access
L-Lactate Dehydrogenase
Non-Small Cell Lung Carcinoma
Immunotherapy
Neutrophils
Lymphocytes

Exploiting FAsting-mimicking Diet and MEtformin to Improve the Efficacy of Platinum-pemetrexed Chemotherapy in Advanced LKB1-inactivated Lung Adenocarcinoma: The FAME Trial

Vernieri, C., Signorelli, D., Galli, G., Ganzinelli, M., Moro, M., Fabbri, A., Tamborini, E., Marabese, M., Caiola, E., Broggini, M., Hollander, L., Gallucci, R., Vandoni, G., Gavazzi, C., Triulzi, T., Colombo, M. P., Rizzo, A. M., Corsetto, P. A., Pruneri, G., de Braud, F. & 3 others, Sozzi, G., Torri, V. & Garassino, M. C., May 2019, In : Clinical Lung Cancer. 20, 3, p. e413-e417

Research output: Contribution to journalArticle

Pemetrexed
Metformin
Platinum
Fasting
Phosphotransferases

Immune-related adverse events correlate with improved survival in patients undergoing anti-PD1 immunotherapy for metastatic melanoma

Indini, A., Di Guardo, L., Cimminiello, C., Prisciandaro, M., Randon, G., De Braud, F. & Del Vecchio, M., Feb 13 2019, In : Journal of Cancer Research and Clinical Oncology. 145, 2, p. 511-521 11 p.

Research output: Contribution to journalArticle

Immunotherapy
Melanoma
Survival
Vitiligo
Programmed Cell Death 1 Receptor

Impact of dexamethasone-sparing regimens on delayed nausea caused by moderately or highly emetogenic chemotherapy: A meta-analysis of randomised evidence

Celio, L., Bonizzoni, E., Zattarin, E., Codega, P., De Braud, F. & Aapro, M., Dec 30 2019, In : BMC Cancer. 19, 1, 1268.

Research output: Contribution to journalArticle

Open Access
Nausea
Dexamethasone
Meta-Analysis
Drug Therapy
Vomiting
Open Access

Impact of systemic and tumor lipid metabolism on everolimus efficacy in advanced pancreatic neuroendocrine tumors (pNETs)

Vernieri, C., Pusceddu, S., Fucà, G., Indelicato, P., Centonze, G., Castagnoli, L., Ferrari, E., Ajazi, A., Pupa, S., Casola, S., Foiani, M., Mazzaferro, V., Pruneri, G., Milione, M. & de Braud, F., Apr 1 2019, In : International Journal of Cancer. 144, 7, p. 1704-1712 9 p.

Research output: Contribution to journalArticle

Neuroendocrine Tumors
Lipid Metabolism
Acetyl-CoA Carboxylase
Disease-Free Survival
Neoplasms

Is a pharmacogenomic panel useful to estimate the risk of oxaliplatin-related neurotoxicity in colorectal cancer patients?

Nichetti, F., Falvella, F. S., Miceli, R., Cheli, S., Gaetano, R., Fucà, G., Infante, G., Martinetti, A., Antoniotti, C., Falcone, A., Di Bartolomeo, M., Cremolini, C., de Braud, F. & Pietrantonio, F., 2019, In : Pharmacogenomics Journal. 19, 5, p. 465-472 8 p.

Research output: Contribution to journalArticle

Is a pharmacogenomic panel useful to estimate the risk of oxaliplatin-related neurotoxicity in colorectal cancer patients?

Nichetti, F., Falvella, F. S., Miceli, R., Cheli, S., Gaetano, R., Fucà, G., Infante, G., Martinetti, A., Antoniotti, C., Falcone, A., Di Bartolomeo, M., Cremolini, C., de Braud, F. & Pietrantonio, F., Oct 1 2019, In : Pharmacogenomics Journal. 19, 5, p. 465-472 8 p.

Research output: Contribution to journalArticle

oxaliplatin
Pharmacogenetics
Colorectal Neoplasms
Single Nucleotide Polymorphism

Lack of Benefit From Anti-EGFR Treatment in RAS and BRAF Wild-type Metastatic Colorectal Cancer With Mucinous Histology or Mucinous Component

Moretto, R., Morano, F., Ongaro, E., Rossini, D., Pietrantonio, F., Casagrande, M., Antoniotti, C., Corallo, S., Marmorino, F., Cortiula, F., Nichetti, F., Borelli, B., Zucchelli, G., Boccaccino, A., Masi, G., de Braud, F., Falcone, A. & Cremolini, C., Jun 2019, In : Clinical Colorectal Cancer. 18, 2, p. 116-124 9 p.

Research output: Contribution to journalArticle

Growth Factor Receptors
Colorectal Neoplasms
Histology
Mucinous Adenocarcinoma
Cytotoxins

Maintenance Therapy with Panitumumab Alone vs Panitumumab Plus Fluorouracil-Leucovorin in Patients with RAS Wild-Type Metastatic Colorectal Cancer: A Phase 2 Randomized Clinical Trial

Pietrantonio, F., Morano, F., Corallo, S., Miceli, R., Lonardi, S., Raimondi, A., Cremolini, C., Rimassa, L., Bergamo, F., Sartore-Bianchi, A., Tampellini, M., Racca, P., Clavarezza, M., Berenato, R., Caporale, M., Antista, M., Niger, M., Smiroldo, V., Murialdo, R., Zaniboni, A. & 10 others, Adamo, V., Tomasello, G., Giordano, M., Petrelli, F., Longarini, R., Cinieri, S., Falcone, A., Zagonel, V., Di Bartolomeo, M. & De Braud, F., Jan 1 2019, In : JAMA oncology.

Research output: Contribution to journalArticle

Leucovorin
Fluorouracil
Colorectal Neoplasms
Randomized Controlled Trials
Therapeutics

Maintenance Therapy With Panitumumab Alone vs Panitumumab Plus Fluorouracil-Leucovorin in Patients With RAS Wild-Type Metastatic Colorectal Cancer: A Phase 2 Randomized Clinical Trial

Pietrantonio, F., Morano, F., Corallo, S., Miceli, R., Lonardi, S., Raimondi, A., Cremolini, C., Rimassa, L., Bergamo, F., Sartore-Bianchi, A., Tampellini, M., Racca, P., Clavarezza, M., Berenato, R., Caporale, M., Antista, M., Niger, M., Smiroldo, V., Murialdo, R., Zaniboni, A. & 10 others, Adamo, V., Tomasello, G., Giordano, M., Petrelli, F., Longarini, R., Cinieri, S., Falcone, A., Zagonel, V., Di Bartolomeo, M. & de Braud, F., Jul 3 2019, In : JAMA oncology. 5, 9, p. 1268-1275 8 p.

Research output: Contribution to journalArticle

Leucovorin
Fluorouracil
Colorectal Neoplasms
Randomized Controlled Trials
Therapeutics

Maintenance Therapy With Panitumumab Alone vs Panitumumab Plus Fluorouracil-Leucovorin in Patients With RAS Wild-Type Metastatic Colorectal Cancer: A Phase 2 Randomized Clinical Trial

Pietrantonio, F., Morano, F., Corallo, S., Miceli, R., Lonardi, S., Raimondi, A., Cremolini, C., Rimassa, L., Bergamo, F., Sartore-Bianchi, A., Tampellini, M., Racca, P., Clavarezza, M., Berenato, R., Caporale, M., Antista, M., Niger, M., Smiroldo, V., Murialdo, R., Zaniboni, A. & 10 others, Adamo, V., Tomasello, G., Giordano, M., Petrelli, F., Longarini, R., Cinieri, S., Falcone, A., Zagonel, V., Di Bartolomeo, M. & de Braud, F., Jul 3 2019, In : JAMA oncology.

Research output: Contribution to journalArticle

Leucovorin
Fluorouracil
Colorectal Neoplasms
Randomized Controlled Trials
Therapeutics

Metronomic Capecitabine With Cyclophosphamide Regimen in Unresectable or Relapsed Pseudomyxoma Peritonei

Raimondi, A., Corallo, S., Niger, M., Antista, M., Randon, G., Morano, F., Milione, M., Kusamura, S., Baratti, D., Guaglio, M., Cremolini, C., Marmorino, F., Di Bartolomeo, M., Deraco, M., De Braud, F. & Pietrantonio, F., Jun 2019, In : Clinical Colorectal Cancer. 18, 2, p. e179-e190

Research output: Contribution to journalArticle

Pseudomyxoma Peritonei
Cyclophosphamide
Disease-Free Survival
Safety
Neutrophils

Negative hyperselection of patients with RAS and BRAF wild-type metastatic colorectal cancer who received panitumumab-based maintenance therapy

Morano, F., Corallo, S., Lonardi, S., Raimondi, A., Cremolini, C., Rimassa, L., Murialdo, R., Zaniboni, A., Sartore-Bianchi, A., Tomasello, G., Racca, P., Clavarezza, M., Adamo, V., Perrone, F., Gloghini, A., Tamborini, E., Busico, A., Martinetti, A., Palermo, F., Loupakis, F. & 5 others, Milione, M., Fucà, G., Di Bartolomeo, M., De Braud, F. & Pietrantonio, F., 2019, In : Journal of Clinical Oncology. 37, 33, p. 3099-3110 12 p.

Research output: Contribution to journalArticle

Negative Hyperselection of Patients With RAS and BRAF Wild-Type Metastatic Colorectal Cancer Who Received Panitumumab-Based Maintenance Therapy

Morano, F., Corallo, S., Lonardi, S., Raimondi, A., Cremolini, C., Rimassa, L., Murialdo, R., Zaniboni, A., Sartore-Bianchi, A., Tomasello, G., Racca, P., Clavarezza, M., Adamo, V., Perrone, F., Gloghini, A., Tamborini, E., Busico, A., Martinetti, A., Palermo, F., Loupakis, F. & 5 others, Milione, M., Fucà, G., Di Bartolomeo, M., de Braud, F. & Pietrantonio, F., Nov 20 2019, In : Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 37, 33, p. 3099-3110 12 p.

Research output: Contribution to journalArticle

Open Access
Disease-Free Survival
Colorectal Neoplasms
Epidermal Growth Factor Receptor
Leucovorin
Survival

Negative Hyperselection of Patients With RAS and BRAF Wild-Type Metastatic Colorectal Cancer Who Received Panitumumab-Based Maintenance Therapy

Morano, F., Corallo, S., Lonardi, S., Raimondi, A., Cremolini, C., Rimassa, L., Murialdo, R., Zaniboni, A., Sartore-Bianchi, A., Tomasello, G., Racca, P., Clavarezza, M., Adamo, V., Perrone, F., Gloghini, A., Tamborini, E., Busico, A., Martinetti, A., Palermo, F., Loupakis, F. & 5 others, Milione, M., Fucà, G., Di Bartolomeo, M., de Braud, F. & Pietrantonio, F., Nov 20 2019, In : Journal of Clinical Oncology. 37, 33, p. 3099-3110 12 p.

Research output: Contribution to journalArticle

Disease-Free Survival
Colorectal Neoplasms
Epidermal Growth Factor Receptor
Leucovorin
Survival

Negative Hyperselection of Patients With RAS and BRAF Wild-Type Metastatic Colorectal Cancer Who Received Panitumumab-Based Maintenance Therapy

Morano, F., Corallo, S., Lonardi, S., Raimondi, A., Cremolini, C., Rimassa, L., Murialdo, R., Zaniboni, A., Sartore-Bianchi, A., Tomasello, G., Racca, P., Clavarezza, M., Adamo, V., Perrone, F., Gloghini, A., Tamborini, E., Busico, A., Martinetti, A., Palermo, F., Loupakis, F. & 5 others, Milione, M., Fucà, G., Di Bartolomeo, M., de Braud, F. & Pietrantonio, F., Nov 20 2019, In : Journal of Clinical Oncology. 37, 33, p. 3099-3110 12 p.

Research output: Contribution to journalArticle

Colorectal Neoplasms
Disease-Free Survival
oxaliplatin
Leucovorin
Epidermal Growth Factor Receptor

Neoadjuvant eribulin mesylate following anthracycline and taxane in triple negative breast cancer: Results from the HOPE study

Cosimo, S. D., Verde, N. L., Moretti, A., Cazzaniga, M. E., Generali, D., Bianchi, G. V., Mariani, L., Torri, V., Crippa, F., Paolini, B., Scaperrotta, G., De Santis, M. C., Nicola, M. D., Apolone, G., Gulino, A., Tripodo, C., Colombo, M. P., Folli, S. & de Braud, F., Jan 1 2019, In : PLoS One. 14, 8, e0220644.

Research output: Contribution to journalArticle

Open Access
eribulin
anthracyclines
Triple Negative Breast Neoplasms
taxanes
Catenins

Nivolumab Alone and With Ipilimumab in Previously Treated Metastatic Urothelial Carcinoma: CheckMate 032 Nivolumab 1 mg/kg Plus Ipilimumab 3 mg/kg Expansion Cohort Results

Sharma, P., Siefker-Radtke, A., de Braud, F., Basso, U., Calvo, E., Bono, P., Morse, M. A., Ascierto, P. A., Lopez-Martin, J., Brossart, P., Rohrberg, K., Mellado, B., Fischer, B. S., Meadows-Shropshire, S., Abdel Saci, Callahan, M. K. & Rosenberg, J., Jul 1 2019, In : Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 37, 19, p. 1608-1616 9 p.

Research output: Contribution to journalArticle

Carcinoma
Platinum
Immunotherapy
Multicenter Studies
Disease Progression

Oral maintenance metronomic vinorelbine versus best supportive care in advanced non-small-cell lung cancer after platinum-based chemotherapy: The MA.NI.LA. multicenter, randomized, controlled, phase II trial

Platania, M., Pasini, F., Porcu, L., Boeri, M., Verderame, F., Modena, Y., Del Conte, A., Nichetti, F., Garassino, M. C., Martinetti, A., Sottotetti, E., Cavanna, L., Vattemi, E., Pozzessere, D., Bertolini, A., Irtelli, L., Verri, C., Sozzi, G., Proto, C., Pastorino, U. & 12 others, Torri, V., Fraccon, A. P., Spinnato, F., Signorelli, D., Lo Russo, G., Tuzi, A., Gallucci, R., Cinieri, S., Mencoboni, M., Antonelli, P., Giacomelli, L. & de Braud, F., Jun 2019, In : Lung Cancer. 132, p. 17-23 7 p.

Research output: Contribution to journalArticle

Platinum
Non-Small Cell Lung Carcinoma
Maintenance
Drug Therapy
Disease-Free Survival

Panitumumab-based maintenance after oxaliplatin discontinuation in metastatic colorectal cancer: A retrospective analysis of two randomised trials

Modest, D. P., Rivera, F., Bachet, J. B., de Braud, F., Pietrantonio, F., Koukakis, R., Demonty, G. & Douillard, J. Y., Jul 15 2019, In : International Journal of Cancer. 145, 2, p. 576-585 10 p.

Research output: Contribution to journalArticle

Open Access
oxaliplatin
Leucovorin
Fluorouracil
Colorectal Neoplasms
Maintenance

Pembrolizumab in the treatment of advanced/metastatic melanoma: A single-center institution experience

Cimminiello, C., Indini, A., Di Guardo, L., Prisciandaro, M., Randon, G., Tolomio, E., De Braud, F. & Del Vecchio, M., Jun 1 2019, In : Melanoma Research. 29, 3, p. 289-294 6 p.

Research output: Contribution to journalArticle

Melanoma
Confidence Intervals
Therapeutics
Proportional Hazards Models
Disease-Free Survival

Perioperative Bevacizumab-based Triplet Chemotherapy in Patients With Potentially Resectable Colorectal Cancer Liver Metastases

Pietrantonio, F., Cotsoglou, C., Fucà, G., Lo Vullo, S., Nichetti, F., Milione, M., Coppa, J., Vaiani, M., Alessi, A., Prisciandaro, M., Droz-Dit Busset, M., Morano, F., Corallo, S., Lazzati, S., Antista, M., Mennitto, A., Randon, G., Raimondi, A., Belfiore, A., Padovano, B. & 5 others, Perrone, F., Mariani, L., Di Bartolomeo, M., de Braud, F. & Mazzaferro, V., Mar 2019, In : Clinical Colorectal Cancer. 18, 1, p. 34-43.e6

Research output: Contribution to journalArticle

Liver Neoplasms
Colorectal Neoplasms
oxaliplatin
irinotecan
Neoplasm Metastasis

Phenethyl isothiocyanate hampers growth and progression of HER2-positive breast and ovarian carcinoma by targeting their stem cell compartment

Koschorke, A., Faraci, S., Giani, D., Chiodoni, C., Iorio, E., Canese, R., Colombo, M. P., Lamolinara, A., Iezzi, M., Ladomery, M., Vernieri, C., de Braud, F., Di Nicola, M., Tagliabue, E., Castagnoli, L. & Pupa, S. M., Dec 1 2019, In : Cellular Oncology. 42, 6, p. 815-828 14 p.

Research output: Contribution to journalArticle

Stem Cells
Breast Neoplasms
Neoplastic Stem Cells
Growth
Neoplasms

Plasma miRNA levels for predicting therapeutic response to neoadjuvant treatment in HER2-positive breast cancer: Results from the NeoALTTO trial

Di Cosimo, S., Appierto, V., Pizzamiglio, S., Tiberio, P., Iorio, M. V., Hilbers, F., De Azambuja, E., De La Peña, L., Izquierdo, M., Huober, J., Baselga, J., Piccart, M., De Braud, F. G., Apolone, G., Verderio, P. & Daidone, M. G., Jan 1 2019, In : Clinical Cancer Research. 25, 13, p. 3887-3895 9 p.

Research output: Contribution to journalArticle

Neoadjuvant Therapy
MicroRNAs
Breast Neoplasms
Disease-Free Survival
Therapeutics

Prognostic impact of ATM mutations in patients with metastatic colorectal cancer

Randon, G., Fucà, G., Rossini, D., Raimondi, A., Pagani, F., Perrone, F., Tamborini, E., Busico, A., Peverelli, G., Morano, F., Niger, M., Antista, M., Corallo, S., Saggio, S., Borelli, B., Zucchelli, G., Milione, M., Pruneri, G., Di Bartolomeo, M., Falcone, A. & 3 others, de Braud, F., Cremolini, C. & Pietrantonio, F., Dec 1 2019, In : Scientific Reports. 9, 1, 2858.

Research output: Contribution to journalArticle

Open Access
Colorectal Neoplasms
Mutation
Survival
Neoplasms
Double-Stranded DNA Breaks

Refining the selection of patients with metastatic colorectal cancer for treatment with temozolomide using proteomic analysis of O6-methylguanine-DNA-methyltransferase

Schwartz, S., Szeto, C., Tian, Y., Cecchi, F., Corallo, S., Calegari, M. A., Di Bartolomeo, M., Morano, F., Raimondi, A., Fucà, G., Martinetti, A., De Pascalis, I., Martini, M., Belfiore, A., Milione, M., Orlandi, A., Barault, L., Barone, C., de Braud, F., Di Nicolantonio, F. & 3 others, Benz, S., Hembrough, T. & Pietrantonio, F., Jan 1 2019, In : European Journal of Cancer. 107, p. 164-174 11 p.

Research output: Contribution to journalArticle

temozolomide
Methyltransferases
Proteomics
Patient Selection
Colorectal Neoplasms

Refining the selection of patients with metastatic colorectal cancer for treatment with temozolomide using proteomic analysis of O6-methylguanine-DNA-methyltransferase

Schwartz, S., Szeto, C., Tian, Y., Cecchi, F., Corallo, S., Calegari, M. A., Di Bartolomeo, M., Morano, F., Raimondi, A., Fucà, G., Martinetti, A., De Pascalis, I., Martini, M., Belfiore, A., Milione, M., Orlandi, A., Barault, L., Barone, C., de Braud, F., Di Nicolantonio, F. & 3 others, Benz, S., Hembrough, T. & Pietrantonio, F., 2019, In : European Journal of Cancer. 107, p. 164-174 11 p.

Research output: Contribution to journalArticle

Safety and antitumor activity of the anti-PD-1 antibody pembrolizumab in patients with advanced, PD-L1-positive papillary or follicular thyroid cancer

Mehnert, J. M., Varga, A., Brose, M. S., Aggarwal, R. R., Lin, C. C., Prawira, A., De Braud, F., Tamura, K., Doi, T., Piha-Paul, S. A., Gilbert, J., Saraf, S., Thanigaimani, P., Cheng, J. D. & Keam, B., Mar 4 2019, In : BMC Cancer. 19, 1, 196.

Research output: Contribution to journalArticle

Open Access
Ligands
Safety
Antibodies
Thyroid Neoplasms
Confidence Intervals

Single-Agent Gemcitabine vs. Carboplatin-Gemcitabine in Advanced Breast Cancer: A Retrospective Comparison of Efficacy and Safety Profiles

Vernieri, C., Prisciandaro, M., Milano, M., Cona, M. S., Maggi, C., Brambilla, M., Mennitto, A., Fabbroni, C., Farè, E., Cresta, S., Celio, L., Mariani, G., Bianchi, G., Capri, G. & de Braud, F., Apr 2019, In : Clinical Breast Cancer. 19, 2, p. e306-e318

Research output: Contribution to journalArticle

gemcitabine
Carboplatin
Breast Neoplasms
Safety
Disease-Free Survival

Single Institution trial of anthracycline- and taxane-based chemotherapy for operable breast cancer: The ASTER study

Mariani, G., Galli, G., Cavalieri, S., Valagussa, P., Bianchi, G. V., Capri, G., Cresta, S., Ferrari, L., Damian, S., Duca, M., de Braud, F. & Moliterni, A., Mar 1 2019, In : Breast Journal. 25, 2, p. 237-242 6 p.

Research output: Contribution to journalArticle

Anthracyclines
Breast Neoplasms
Drug Therapy
Paclitaxel
Methotrexate