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Research Output

2020

Comparative characterization of B cells specific for HBV nucleocapsid and envelope proteins in patients with chronic hepatitis B

Le Bert, N., Salimzadeh, L., Gill, U. S., Dutertre, C. A., Facchetti, F., Tan, A., Hung, M., Novikov, N., Lampertico, P., Fletcher, S. P., Kennedy, P. T. F. & Bertoletti, A., 2020, In : Journal of Hepatology. 72, 1, p. 34-44

Research output: Contribution to journalArticle

2019

A practical algorithmic approach to mature aggressive B cell lymphoma diagnosis in the double/triple hit era: selecting cases, matching clinical benefit : A position paper from the Italian Group of Haematopathology (G.I.E.)

Di Napoli, A., Remotti, D., Agostinelli, C., Ambrosio, M. R., Ascani, S., Carbone, A., Facchetti, F., Lazzi, S., Leoncini, L., Lucioni, M., Novero, D., Pileri, S., Ponzoni, M., Sabattini, E., Tripodo, C., Zamò, A., Paulli, M. & Ruco, L., Oct 2019, In : Virchows Archiv - A Pathological Anatomy and Histopathology. 475, 4, p. 513-518 6 p.

Research output: Contribution to journalArticle

A practical algorithmic approach to mature aggressive B cell lymphoma diagnosis in the double/triple hit era: selecting cases, matching clinical benefit: A position paper from the Italian Group of Haematopathology (G.I.E.)

Di Napoli, A., Remotti, D., Agostinelli, C., Ambrosio, M. R., Ascani, S., Carbone, A., Facchetti, F., Lazzi, S., Leoncini, L., Lucioni, M., Novero, D., Pileri, S., Ponzoni, M., Sabattini, E., Tripodo, C., Zamò, A., Paulli, M. & Ruco, L., Jan 1 2019, In : Virchows Archiv.

Research output: Contribution to journalArticle

Blastic plasmacytoid dendritic cell neoplasm: Genomics mark epigenetic dysregulation as a primary therapeutic target

Sapienza, M. R., Abate, F., Melle, F., Orecchioni, S., Fuligni, F., Etebari, M., Tabanelli, V., Laginestra, M. A., Pileri, A., Motta, G., Rossi, M., Agostinelli, C., Sabattini, E., Pimpinelli, N., Truni, M., Falini, B., Cerroni, L., Talarico, G., Piccioni, R., Amente, S. & 11 others, Indio, V., Tarantino, G., Brundu, F., Paulli, M., Berti, E., Facchetti, F., Dellino, G. I., Bertolini, F., Tripodo, C., Rabadan, R. & Pileri, S. A., 2019, In : Haematologica. 104, 4, p. 729-737 9 p.

Research output: Contribution to journalArticle

Blastic plasmacytoid dendritic cell neoplasm: Genomics mark epigenetic dysregulation as a primary therapeutic target

Sapienza, M. R., Abate, F., Melle, F., Orecchioni, S., Fuligni, F., Etebari, M., Tabanelli, V., Laginestra, M. A., Pileri, A., Motta, G., Rossi, M., Agostinelli, C., Sabattini, E., Pimpinelli, N., Truni, M., Falini, B., Cerroni, L., Talarico, G., Piccioni, R., Amente, S. & 11 others, Indio, V., Tarantino, G., Brundu, F., Paulli, M., Berti, E., Facchetti, F., Dellino, G. I., Bertolini, F., Tripodo, C., Rabadan, R. & Pileri, S. A., 2019, In : Haematologica. 104, 4, p. 729-737 9 p.

Research output: Contribution to journalArticle

Dose-adjusted EPOCH plus rituximab improves the clinical outcome of young patients affected by double expressor diffuse large B-cell lymphoma

Dodero, A., Guidetti, A., Tucci, A., Barretta, F., Novo, M., Devizzi, L., Re, A., Passi, A., Pellegrinelli, A., Pruneri, G., Miceli, R., Testi, A., Pennisi, M., Di Chio, M. C., Matteucci, P., Carniti, C., Facchetti, F., Rossi, G. & Corradini, P., Apr 1 2019, In : Leukemia. 33, 4, p. 1047-1051 5 p.

Research output: Contribution to journalLetter

Open Access

Effectiveness and safety of switching to entecavir hepatitis B patients developing kidney dysfunction during tenofovir

Viganò, M., Loglio, A., Labanca, S., Zaltron, S., Castelli, F., Andreone, P., Messina, V., Ganga, R., Coppola, N., Marrone, A., Russello, M., Marzano, A., Tucci, A., Taliani, G., Fasano, M., Fagiuoli, S., Villa, E., Bronte, F., Santantonio, T., Brancaccio, G. & 5 others, Occhipinti, V., Facchetti, F., Grossi, G., Rumi, M. & Lampertico, P., Mar 1 2019, In : Liver International. 39, 3, p. 484-493 10 p.

Research output: Contribution to journalArticle

Minimal increases of serum alpha-foetoprotein herald HCC detection in Caucasian HBV cirrhotic patients under long-term oral therapy

Loglio, A., Iavarone, M., Viganò, M., Orenti, A., Facchetti, F., Cortinovis, I., Lunghi, G., Ceriotti, F., Occhipinti, V., Rumi, M., Sangiovanni, A., Colombo, M. & Lampertico, P., Jan 1 2019, In : Liver International. 39, 10, p. 1964-1974 11 p.

Research output: Contribution to journalArticle

Minimal increases of serum alpha-foetoprotein herald HCC detection in Caucasian HBV cirrhotic patients under long-term oral therapy

Loglio, A., Iavarone, M., Viganò, M., Orenti, A., Facchetti, F., Cortinovis, I., Lunghi, G., Ceriotti, F., Occhipinti, V., Rumi, M., Sangiovanni, A., Colombo, M. & Lampertico, P., Jan 1 2019, In : Liver International. 39, 10, p. 1964-1974

Research output: Contribution to journalArticle

Serum hepatitis B core-related antigen (HBcrAg) correlates with covalently closed circular DNA transcriptional activity in chronic hepatitis B patients

Testoni, B., Lebossé, F., Scholtes, C., Berby, F., Miaglia, C., Subic, M., Loglio, A., Facchetti, F., Lampertico, P., Levrero, M. & Zoulim, F., Apr 1 2019, In : Journal of Hepatology. 70, 4, p. 615-625 11 p.

Research output: Contribution to journalArticle

2018

Hepatitis delta virus and hepatocellular carcinoma: an update

Romeo, R., Petruzziello, A., Pecheur, E. I., Facchetti, F., Perbellini, R., Galmozzi, E., Khan, N. U., Di Capua, L., Sabatino, R., Botti, G. & Loquercio, G., 2018, In : Epidemiology and Infection. 146, 13, p. 1612-1618 7 p.

Research output: Contribution to journalArticle

IFNL4 rs368234815 and rs117648444 variants predict off-treatment HBsAg seroclearance in IFN-treated HBeAg-negative chronic hepatitis B patients

Galmozzi, E., Facchetti, F., Grossi, G., Loglio, A., Viganò, M., Lunghi, G., Colombo, M. & Lampertico, P., Mar 1 2018, In : Liver International. 38, 3, p. 417-423 7 p.

Research output: Contribution to journalArticle

IFNL4 rs368234815 and rs117648444 variants predict off-treatment HBsAg seroclearance in IFN-treated HBeAg-negative chronic hepatitis B patients

Galmozzi, E., Facchetti, F., Grossi, G., Loglio, A., Viganò, M., Lunghi, G., Colombo, M. & Lampertico, P., Mar 2018, In : Liver International. 38, 3, p. 417-423 7 p.

Research output: Contribution to journalArticle

TLR7 Agonist Increases Responses of Hepatitis B Virus–Specific T Cells and Natural Killer Cells in Patients With Chronic Hepatitis B Treated With Nucleos(T)Ide Analogues

Boni, C., Vecchi, A., Rossi, M., Laccabue, D., Giuberti, T., Alfieri, A., Lampertico, P., Grossi, G., Facchetti, F., Brunetto, M. R., Coco, B., Cavallone, D., Mangia, A., Santoro, R., Piazzolla, V., Lau, A., Gaggar, A., Subramanian, G. M. & Ferrari, C., May 1 2018, In : Gastroenterology. 154, 6, p. 1764-1777.e7

Research output: Contribution to journalArticle

2017

Intrahepatic innate immune response pathways are downregulated in untreated chronic hepatitis B

Lebossé, F., Testoni, B., Fresquet, J., Facchetti, F., Galmozzi, E., Fournier, M., Hervieu, V., Berthillon, P., Berby, F., Bordes, I., Durantel, D., Levrero, M., Lampertico, P. & Zoulim, F., May 1 2017, In : Journal of Hepatology. 66, 5, p. 897-909 13 p.

Research output: Contribution to journalArticle

2016

eNOS polymorphisms and clinical outcome in advanced HCC patients receiving sorafenib: Final results of the ePHAS study

Gardini, A. C., Marisi, G., Faloppi, L., Scarpi, E., Foschi, F. G., Iavarone, M., Lauletta, G., Corbelli, J., Valgiusti, M., Facchetti, F., della Corte, C., Neri, L. M., Tamberi, S., Cascinu, S., Scartozzi, M., Amadori, D., Nanni, O., Tenti, E., Ulivi, P. & Frassineti, G. L., May 10 2016, In : Oncotarget. 7, 19, p. 27988-27999 12 p.

Research output: Contribution to journalArticle

eNOS polymorphisms and clinical outcome in advanced HCC patients receiving sorafenib: Final results of the ePHAS study

Casadei Gardini, A., Marisi, G., Faloppi, L., Scarpi, E., Foschi, F. G., Iavarone, M., Lauletta, G., Corbelli, J., Valgiusti, M., Facchetti, F., Della Corte, C., Neri, L. M., Tamberi, S., Cascinu, S., Scartozzi, M., Amadori, D., Nanni, O., Tenti, E., Ulivi, P. & Frassineti, G. L. P., May 10 2016, In : Oncotarget. 7, 19, p. 27988-27999 12 p.

Research output: Contribution to journalArticle

Lack of Siglec-7 expression identifies a dysfunctional natural killer cell subset associated with liver inflammation and fibrosis in chronic HCV infection

Varchetta, S., Mele, D., Lombardi, A., Oliviero, B., Mantovani, S., Tinelli, C., Spreafico, M., Prati, D., Ludovisi, S., Ferraioli, G., Filice, C., Aghemo, A., Lampertico, P., Facchetti, F., Bernuzzi, F., Invernizzi, P. & Mondelli, M. U., Dec 1 2016, In : Gut. 65, 12, p. 1998-2006 9 p.

Research output: Contribution to journalArticle

Lack of Siglec-7 expression identifies a dysfunctional natural killer cell subset associated with liver inflammation and fibrosis in chronic HCV infection

Varchetta, S., Mele, D., Lombardi, A., Oliviero, B., Mantovani, S., Tinelli, C., Spreafico, M., Prati, D., Ludovisi, S., Ferraioli, G., Filice, C., Aghemo, A. M., Lampertico, P., Facchetti, F., Bernuzzi, F., Invernizzi, P. & Mondelli, M. U., Dec 1 2016, In : Gut. 65, 12, p. 1998-2006 9 p.

Research output: Contribution to journalArticle

Lack of Siglec-7 expression identifies a dysfunctional natural killer cell subset associated with liver inflammation and fibrosis in chronic HCV infection

Varchetta, S., Mele, D., Lombardi, A., Oliviero, B., Mantovani, S., Tinelli, C., Spreafico, M., Prati, D., Ludovisi, S., Ferraioli, G., Filice, C., Aghemo, A., Lampertico, P., Facchetti, F., Bernuzzi, F., Invernizzi, P. & Mondelli, M. U., Dec 1 2016, In : Gut. 65, 12, p. 1998-2006 9 p.

Research output: Contribution to journalArticle

Serological tests do not predict residual fibrosis in hepatitis C cirrhotics with a sustained virological response to interferon

D'Ambrosio, R., Degasperi, E., Aghemo, A., Fraquelli, M., Lampertico, P., Rumi, M. G., Facchetti, F., Grassi, E., Casazza, G., Rosenberg, W., Bedossa, P. & Colombo, M., Jun 1 2016, In : PLoS One. 11, 6, e0155967.

Research output: Contribution to journalArticle

2015

The long-term benefits of nucleos(t)ide analogs in compensated HBV cirrhotic patients with no or small esophageal varices: A 12-year prospective cohort study

Lampertico, P., Invernizzi, F., Viganò, M., Loglio, A., Mangia, G., Facchetti, F., Primignani, M., Jovani, M., Iavarone, M., Fraquelli, M., Casazza, G., De Franchis, R. & Colombo, M., Nov 1 2015, In : Journal of Hepatology. 63, 5, p. 1118-1125 8 p.

Research output: Contribution to journalArticle

2014

High-resolution melting assay for genotyping of IFNL4-associated dinucleotide variant rs368234815

Galmozzi, E., Facchetti, F., Perbellini, R. & Aghemo, A., Nov 1 2014, In : Clinical Microbiology and Infection. 20, 11, p. O936-O938

Research output: Contribution to journalArticle

Performance of Enhanced Liver Fibrosis test and comparison with transient elastography in the identification of liver fibrosis in patients with chronic hepatitis B infection

Trembling, P. M., Lampertico, P., Parkes, J., Tanwar, S., Viganò, M., Facchetti, F., Colombo, M. & Rosenberg, W. M., 2014, In : Journal of Viral Hepatitis. 21, 6, p. 430-438 9 p.

Research output: Contribution to journalArticle

Tenofovir-induced Fanconi syndrome in chronic hepatitis B monoinfected patients that reverted after tenofovir withdrawal

Viganò, M., Brocchieri, A., Spinetti, A., Zaltron, S., Mangia, G., Facchetti, F., Fugazza, A., Castelli, F., Colombo, M. & Lampertico, P., 2014, In : Journal of Clinical Virology. 61, 4, p. 600-603 4 p.

Research output: Contribution to journalArticle

VEGF and VEGFR genotyping in the prediction of clinical outcome for HCC patients receiving sorafenib: The ALICE-1 study

Scartozzi, M., Faloppi, L., Svegliati Baroni, G., Loretelli, C., Piscaglia, F., Iavarone, M., Toniutto, P., Fava, G., De Minicis, S., Mandolesi, A., Bianconi, M., Giampieri, R., Granito, A., Facchetti, F., Bitetto, D., Marinelli, S., Venerandi, L., Vavassori, S., Gemini, S., D'Errico, A. & 5 others, Colombo, M., Bolondi, L., Bearzi, I., Benedetti, A. & Cascinu, S., Sep 1 2014, In : International Journal of Cancer. 135, 5, p. 1247-1256 10 p.

Research output: Contribution to journalArticle

2013

IL28B polymorphisms predict interferon-related hepatitis B surface antigen seroclearance in genotype D hepatitis B e antigen-negative patients with chronic hepatitis B

Lampertico, P., Viganò, M., Cheroni, C., Facchetti, F., Invernizzi, F., Valveri, V., Soffredini, R., Abrignani, S., De Francesco, R. & Colombo, M., Mar 2013, In : Hepatology. 57, 3, p. 890-896 7 p.

Research output: Contribution to journalArticle

Patatin-like phospholipase domain-containing 3 I148M affects liver steatosis in patients with chronic hepatitis B

Viganò, M., Valenti, L., Lampertico, P., Facchetti, F., Motta, B. M., D'Ambrosio, R., Romagnoli, S., Dongiovanni, P., Donati, B., Fargion, S. & Colombo, M., Oct 2013, In : Hepatology. 58, 4, p. 1245-1252 8 p.

Research output: Contribution to journalArticle

Randomised study comparing 48 and 96 weeks peginterferon α-2a therapy in genotype D HBeAg-negative chronic hepatitis B

Lampertico, P., Viganò, M., Di Costanzo, G. G., Sagnelli, E., Fasano, M., Di Marco, V., Boninsegna, S., Farci, P., Fargion, S., Giuberti, T., Iannacone, C., Regep, L., Massetto, B., Facchetti, F. & Colombo, M., Feb 2013, In : Gut. 62, 2, p. 290-298 9 p.

Research output: Contribution to journalArticle

2011

Long-term add-on therapy with adefovir in lamivudine-resistant kidney graft recipients with chronic hepatitis B

Lampertico, P., Vigan, M., Facchetti, F., Invernizzi, F., Aroldi, A., Lunghi, G., Messa, P. G. & Colombo, M., Jun 2011, In : Nephrology Dialysis Transplantation. 26, 6, p. 2037-2041 5 p.

Research output: Contribution to journalArticle

Risk of hepatitis B surface antigen seroreversion after allogeneic hematopoietic SCT

Viganò, M., Vener, C., Lampertico, P., Annaloro, C., Pichoud, C., Zoulim, F., Facchetti, F., Poli, F., Scalamogna, M., Deliliers, G. L. & Colombo, M., Jan 2011, In : Bone Marrow Transplantation. 46, 1, p. 125-131 7 p.

Research output: Contribution to journalArticle

2008
2007

Effect of a caloric restriction regimen on the angiogenic capacity of aorta and on the expression of endothelin-1 during ageing

Facchetti, F., Monzani, E., Cavallini, G., Bergamini, E. & La Porta, C. A. M., Jul 2007, In : Experimental Gerontology. 42, 7, p. 662-667 6 p.

Research output: Contribution to journalArticle

Melanoma contains CD133 and ABCG2 positive cells with enhanced tumourigenic potential

Monzani, E., Facchetti, F., Galmozzi, E., Corsini, E., Benetti, A., Cavazzin, C., Gritti, A., Piccinini, A., Porro, D., Santinami, M., Invernici, G., Parati, E., Alessandri, G. & La Porta, C. A. M., Mar 2007, In : European Journal of Cancer. 43, 5, p. 935-946 12 p.

Research output: Contribution to journalArticle

New perspectives in the treatment of Melanoma: Anti-angiogenic and anti-lymphangiogenic strategies

Facchetti, F., Monzani, E. & La Porta, C. A. M., Jan 2007, In : Recent Patents on Anti-Cancer Drug Discovery. 2, 1, p. 73-78 6 p.

Research output: Contribution to journalArticle

2006

BRAF V599E mutation occurs in Spitz and Reed naevi [24]

La Porta, C. A. M., Cardano, R., Facchetti, F., Presicce, P., Rao, S., Privitera, E., Clemente, C. & Mihm, M. C., Oct 2006, In : Journal of the European Academy of Dermatology and Venereology. 20, 9, p. 1164-1165 2 p.

Research output: Contribution to journalArticle

Cancer stem cells and therapeutic perspectives

Galmozzi, E., Facchetti, F. & La Porta, C. A. M., Mar 2006, In : Current Medicinal Chemistry. 13, 6, p. 603-607 5 p.

Research output: Contribution to journalArticle

Unique expression and localization of aquaporin- 4 and aquaporin-9 in murine and human neural stem cells and in their glial progeny

Cavazzin, C., Ferrari, D., Facchetti, F., Russignan, A., Vescovi, A. L., La Porta, C. A. M. & Gritti, A., Jan 15 2006, In : GLIA. 53, 2, p. 167-181 15 p.

Research output: Contribution to journalArticle

2004

Modulation of pro- and anti-apoptotic factors in human melanoma cells exposed to histone deacetylase inhibitors

Facchetti, F., Previdi, S., Ballarini, M., Minucci, S., Perego, P. & Porta, C. A. M. L., Sep 2004, In : Apoptosis. 9, 5, p. 573-582 10 p.

Research output: Contribution to journalArticle