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Research Output 2001 2020

2020

Comparative characterization of B cells specific for HBV nucleocapsid and envelope proteins in patients with chronic hepatitis B

Le Bert, N., Salimzadeh, L., Gill, U. S., Dutertre, C. A., Facchetti, F., Tan, A., Hung, M., Novikov, N., Lampertico, P., Fletcher, S. P., Kennedy, P. T. F. & Bertoletti, A., 2020, In : Journal of Hepatology. 72, 1, p. 34-44

Research output: Contribution to journalArticle

Nucleocapsid Proteins
Chronic Hepatitis B
B-Lymphocytes
Hepatitis B Core Antigens
Hepatitis B Surface Antigens
2019

A practical algorithmic approach to mature aggressive B cell lymphoma diagnosis in the double/triple hit era: selecting cases, matching clinical benefit: A position paper from the Italian Group of Haematopathology (G.I.E.)

Di Napoli, A., Remotti, D., Agostinelli, C., Ambrosio, M. R., Ascani, S., Carbone, A., Facchetti, F., Lazzi, S., Leoncini, L., Lucioni, M., Novero, D., Pileri, S., Ponzoni, M., Sabattini, E., Tripodo, C., Zamò, A., Paulli, M. & Ruco, L., Jan 1 2019, In : Virchows Archiv.

Research output: Contribution to journalArticle

B-Cell Lymphoma
Cytogenetics
Therapeutics

Blastic plasmacytoid dendritic cell neoplasm: Genomics mark epigenetic dysregulation as a primary therapeutic target

Sapienza, M. R., Abate, F., Melle, F., Orecchioni, S., Fuligni, F., Etebari, M., Tabanelli, V., Laginestra, M. A., Pileri, A., Motta, G., Rossi, M., Agostinelli, C., Sabattini, E., Pimpinelli, N., Truni, M., Falini, B., Cerroni, L., Talarico, G., Piccioni, R., Amente, S. & 11 others, Indio, V., Tarantino, G., Brundu, F., Paulli, M., Berti, E., Facchetti, F., Dellino, G. I., Bertolini, F., Tripodo, C., Rabadan, R. & Pileri, S. A., 2019, In : Haematologica. 104, 4, p. 729-737 9 p.

Research output: Contribution to journalArticle

Genomics
Epigenomics
Dendritic Cells
Exome
Hematologic Neoplasms

Dose-adjusted EPOCH plus rituximab improves the clinical outcome of young patients affected by double expressor diffuse large B-cell lymphoma

Dodero, A., Guidetti, A., Tucci, A., Barretta, F., Novo, M., Devizzi, L., Re, A., Passi, A., Pellegrinelli, A., Pruneri, G., Miceli, R., Testi, A., Pennisi, M., Di Chio, M. C., Matteucci, P., Carniti, C., Facchetti, F., Rossi, G. & Corradini, P., Apr 1 2019, In : Leukemia. 33, 4, p. 1047-1051 5 p.

Research output: Contribution to journalLetter

Open Access

Effectiveness and safety of switching to entecavir hepatitis B patients developing kidney dysfunction during tenofovir

Viganò, M., Loglio, A., Labanca, S., Zaltron, S., Castelli, F., Andreone, P., Messina, V., Ganga, R., Coppola, N., Marrone, A., Russello, M., Marzano, A., Tucci, A., Taliani, G., Fasano, M., Fagiuoli, S., Villa, E., Bronte, F., Santantonio, T., Brancaccio, G. & 5 others, Occhipinti, V., Facchetti, F., Grossi, G., Rumi, M. & Lampertico, P., Mar 1 2019, In : Liver International. 39, 3, p. 484-493 10 p.

Research output: Contribution to journalArticle

Tenofovir
Hepatitis B
Kidney
Safety
Lamivudine
Hepatitis B Core Antigens
Hepatitis B Antibodies
Lamivudine
Hepatitis B virus
Non-Hodgkin's Lymphoma

Minimal increases of serum alpha-foetoprotein herald HCC detection in Caucasian HBV cirrhotic patients under long-term oral therapy

Loglio, A., Iavarone, M., Viganò, M., Orenti, A., Facchetti, F., Cortinovis, I., Lunghi, G., Ceriotti, F., Occhipinti, V., Rumi, M., Sangiovanni, A., Colombo, M. & Lampertico, P., Jan 1 2019, In : Liver International. 39, 10, p. 1964-1974

Research output: Contribution to journalArticle

alpha-Fetoproteins
Hepatitis B virus
Hepatocellular Carcinoma
Serum
Therapeutics

Serum hepatitis B core-related antigen (HBcrAg) correlates with covalently closed circular DNA transcriptional activity in chronic hepatitis B patients

Testoni, B., Lebossé, F., Scholtes, C., Berby, F., Miaglia, C., Subic, M., Loglio, A., Facchetti, F., Lampertico, P., Levrero, M. & Zoulim, F., Apr 1 2019, In : Journal of Hepatology. 70, 4, p. 615-625 11 p.

Research output: Contribution to journalArticle

Hepatitis B Core Antigens
Circular DNA
Chronic Hepatitis B
Serum
Hepatitis B e Antigens
Hepacivirus
Antiviral Agents
Hepatocellular Carcinoma
Genes
Fibrosis
2018
Hepatitis B
Hepatocellular Carcinoma
Hepatitis B virus
Therapeutics
Liver Transplantation
Hepatitis B
Hepatocellular Carcinoma
Hepatitis B virus
Therapeutics
Liver Transplantation

Hepatitis delta virus and hepatocellular carcinoma: an update

Romeo, R., Petruzziello, A., Pecheur, E. I., Facchetti, F., Perbellini, R., Galmozzi, E., Khan, N. U., Di Capua, L., Sabatino, R., Botti, G. & Loquercio, G., 2018, In : Epidemiology and Infection. 146, 13, p. 1612-1618 7 p.

Research output: Contribution to journalArticle

Hepatitis Delta Virus
Hepatocellular Carcinoma
Virus Diseases
Hepatitis B virus
Hepatitis D

IFNL4 rs368234815 and rs117648444 variants predict off-treatment HBsAg seroclearance in IFN-treated HBeAg-negative chronic hepatitis B patients

Galmozzi, E., Facchetti, F., Grossi, G., Loglio, A., Viganò, M., Lunghi, G., Colombo, M. & Lampertico, P., Mar 2018, In : Liver International. 38, 3, p. 417-423 7 p.

Research output: Contribution to journalArticle

Hepatitis B e Antigens
Chronic Hepatitis B
Hepatitis B Surface Antigens
Interferons
Therapeutics

IFNL4 rs368234815 and rs117648444 variants predict off-treatment HBsAg seroclearance in IFN-treated HBeAg-negative chronic hepatitis B patients

Galmozzi, E., Facchetti, F., Grossi, G., Loglio, A., Viganò, M., Lunghi, G., Colombo, M. & Lampertico, P., Mar 1 2018, In : Liver International. 38, 3, p. 417-423 7 p.

Research output: Contribution to journalArticle

Hepatitis B e Antigens
Chronic Hepatitis B
Hepatitis B Surface Antigens
Interferons
Therapeutics
Tenofovir
Fanconi Syndrome
Multiple Drug Resistance
Fibrosis
Lamivudine

TLR7 Agonist Increases Responses of Hepatitis B Virus–Specific T Cells and Natural Killer Cells in Patients With Chronic Hepatitis B Treated With Nucleos(T)Ide Analogues

Boni, C., Vecchi, A., Rossi, M., Laccabue, D., Giuberti, T., Alfieri, A., Lampertico, P., Grossi, G., Facchetti, F., Brunetto, M. R., Coco, B., Cavallone, D., Mangia, A., Santoro, R., Piazzolla, V., Lau, A., Gaggar, A., Subramanian, G. M. & Ferrari, C., May 1 2018, In : Gastroenterology. 154, 6, p. 1764-1777.e7

Research output: Contribution to journalArticle

Chronic Hepatitis B
Hepatitis B
Natural Killer Cells
Hepatitis B virus
T-Lymphocytes
2017

Intrahepatic innate immune response pathways are downregulated in untreated chronic hepatitis B

Lebossé, F., Testoni, B., Fresquet, J., Facchetti, F., Galmozzi, E., Fournier, M., Hervieu, V., Berthillon, P., Berby, F., Bordes, I., Durantel, D., Levrero, M., Lampertico, P. & Zoulim, F., May 1 2017, In : Journal of Hepatology. 66, 5, p. 897-909 13 p.

Research output: Contribution to journalArticle

Chronic Hepatitis B
Innate Immunity
Hepatitis B virus
Down-Regulation
Hepatitis B Surface Antigens
2016

eNOS polymorphisms and clinical outcome in advanced HCC patients receiving sorafenib: Final results of the ePHAS study

Casadei Gardini, A., Marisi, G., Faloppi, L., Scarpi, E., Foschi, F. G., Iavarone, M., Lauletta, G., Corbelli, J., Valgiusti, M., Facchetti, F., Della Corte, C., Neri, L. M., Tamberi, S., Cascinu, S., Scartozzi, M., Amadori, D., Nanni, O., Tenti, E., Ulivi, P. & Frassineti, G. L. P., May 10 2016, In : Oncotarget. 7, 19, p. 27988-27999 12 p.

Research output: Contribution to journalArticle

Nitric Oxide Synthase Type III
Hepatocellular Carcinoma
Haplotypes
Survival
sorafenib

eNOS polymorphisms and clinical outcome in advanced HCC patients receiving sorafenib: Final results of the ePHAS study

Gardini, A. C., Marisi, G., Faloppi, L., Scarpi, E., Foschi, F. G., Iavarone, M., Lauletta, G., Corbelli, J., Valgiusti, M., Facchetti, F., della Corte, C., Neri, L. M., Tamberi, S., Cascinu, S., Scartozzi, M., Amadori, D., Nanni, O., Tenti, E., Ulivi, P. & Frassineti, G. L., May 10 2016, In : Oncotarget. 7, 19, p. 27988-27999 12 p.

Research output: Contribution to journalArticle

Nitric Oxide Synthase Type III
Hepatocellular Carcinoma
Haplotypes
Survival
sorafenib

Lack of Siglec-7 expression identifies a dysfunctional natural killer cell subset associated with liver inflammation and fibrosis in chronic HCV infection

Varchetta, S., Mele, D., Lombardi, A., Oliviero, B., Mantovani, S., Tinelli, C., Spreafico, M., Prati, D., Ludovisi, S., Ferraioli, G., Filice, C., Aghemo, A. M., Lampertico, P., Facchetti, F., Bernuzzi, F., Invernizzi, P. & Mondelli, M. U., Dec 1 2016, In : Gut. 65, 12, p. 1998-2006 9 p.

Research output: Contribution to journalArticle

Sialic Acid Binding Immunoglobulin-like Lectins
Natural Killer Cells
Liver Cirrhosis
Inflammation
Infection

Lack of Siglec-7 expression identifies a dysfunctional natural killer cell subset associated with liver inflammation and fibrosis in chronic HCV infection

Varchetta, S., Mele, D., Lombardi, A., Oliviero, B., Mantovani, S., Tinelli, C., Spreafico, M., Prati, D., Ludovisi, S., Ferraioli, G., Filice, C., Aghemo, A., Lampertico, P., Facchetti, F., Bernuzzi, F., Invernizzi, P. & Mondelli, M. U., Dec 1 2016, In : Gut. 65, 12, p. 1998-2006 9 p.

Research output: Contribution to journalArticle

Sialic Acid Binding Immunoglobulin-like Lectins
Natural Killer Cells
Liver Cirrhosis
Inflammation
Infection

Lack of Siglec-7 expression identifies a dysfunctional natural killer cell subset associated with liver inflammation and fibrosis in chronic HCV infection

Varchetta, S., Mele, D., Lombardi, A., Oliviero, B., Mantovani, S., Tinelli, C., Spreafico, M., Prati, D., Ludovisi, S., Ferraioli, G., Filice, C., Aghemo, A., Lampertico, P., Facchetti, F., Bernuzzi, F., Invernizzi, P. & Mondelli, M. U., Dec 1 2016, In : Gut. 65, 12, p. 1998-2006 9 p.

Research output: Contribution to journalArticle

Sialic Acid Binding Immunoglobulin-like Lectins
Natural Killer Cells
Liver Cirrhosis
Inflammation
Infection

Serological tests do not predict residual fibrosis in hepatitis C cirrhotics with a sustained virological response to interferon

D'Ambrosio, R., Degasperi, E., Aghemo, A., Fraquelli, M., Lampertico, P., Rumi, M. G., Facchetti, F., Grassi, E., Casazza, G., Rosenberg, W., Bedossa, P. & Colombo, M., Jun 1 2016, In : PLoS One. 11, 6, e0155967.

Research output: Contribution to journalArticle

hepatitis C
Serologic Tests
immunologic techniques
interferons
Hepatitis C
2015

The long-term benefits of nucleos(t)ide analogs in compensated HBV cirrhotic patients with no or small esophageal varices: A 12-year prospective cohort study

Lampertico, P., Invernizzi, F., Viganò, M., Loglio, A., Mangia, G., Facchetti, F., Primignani, M., Jovani, M., Iavarone, M., Fraquelli, M., Casazza, G., De Franchis, R. & Colombo, M., Nov 1 2015, In : Journal of Hepatology. 63, 5, p. 1118-1125 8 p.

Research output: Contribution to journalArticle

compound A 12
Esophageal and Gastric Varices
Hepatitis B virus
Cohort Studies
Prospective Studies
2014

High-resolution melting assay for genotyping of IFNL4-associated dinucleotide variant rs368234815

Galmozzi, E., Facchetti, F., Perbellini, R. & Aghemo, A., Nov 1 2014, In : Clinical Microbiology and Infection. 20, 11, p. O936-O938

Research output: Contribution to journalArticle

Chronic Hepatitis C
Freezing
Genetic Markers
Hepacivirus
Interferons

Performance of Enhanced Liver Fibrosis test and comparison with transient elastography in the identification of liver fibrosis in patients with chronic hepatitis B infection

Trembling, P. M., Lampertico, P., Parkes, J., Tanwar, S., Viganò, M., Facchetti, F., Colombo, M. & Rosenberg, W. M., 2014, In : Journal of Viral Hepatitis. 21, 6, p. 430-438 9 p.

Research output: Contribution to journalArticle

Elasticity Imaging Techniques
Chronic Hepatitis B
Liver Cirrhosis
Fibrosis
Infection

Tenofovir-induced Fanconi syndrome in chronic hepatitis B monoinfected patients that reverted after tenofovir withdrawal

Viganò, M., Brocchieri, A., Spinetti, A., Zaltron, S., Mangia, G., Facchetti, F., Fugazza, A., Castelli, F., Colombo, M. & Lampertico, P., 2014, In : Journal of Clinical Virology. 61, 4, p. 600-603 4 p.

Research output: Contribution to journalArticle

Tenofovir
Fanconi Syndrome
Chronic Hepatitis B
Hepatitis B virus
HIV

VEGF and VEGFR genotyping in the prediction of clinical outcome for HCC patients receiving sorafenib: The ALICE-1 study

Scartozzi, M., Faloppi, L., Svegliati Baroni, G., Loretelli, C., Piscaglia, F., Iavarone, M., Toniutto, P., Fava, G., De Minicis, S., Mandolesi, A., Bianconi, M., Giampieri, R., Granito, A., Facchetti, F., Bitetto, D., Marinelli, S., Venerandi, L., Vavassori, S., Gemini, S., D'Errico, A. & 5 others, Colombo, M., Bolondi, L., Bearzi, I., Benedetti, A. & Cascinu, S., Sep 1 2014, In : International Journal of Cancer. 135, 5, p. 1247-1256 10 p.

Research output: Contribution to journalArticle

Vascular Endothelial Growth Factor Receptor
Vascular Endothelial Growth Factor A
Hepatocellular Carcinoma
Single Nucleotide Polymorphism
Disease-Free Survival
2013
Single Nucleotide Polymorphism
Alleles
Chronic Hepatitis C
Virus Diseases
Hepacivirus

IL28B polymorphisms predict interferon-related hepatitis B surface antigen seroclearance in genotype D hepatitis B e antigen-negative patients with chronic hepatitis B

Lampertico, P., Viganò, M., Cheroni, C., Facchetti, F., Invernizzi, F., Valveri, V., Soffredini, R., Abrignani, S., De Francesco, R. & Colombo, M., Mar 2013, In : Hepatology. 57, 3, p. 890-896 7 p.

Research output: Contribution to journalArticle

Hepatitis B e Antigens
Chronic Hepatitis B
Hepatitis B Surface Antigens
Interferons
Genotype

Patatin-like phospholipase domain-containing 3 I148M affects liver steatosis in patients with chronic hepatitis B

Viganò, M., Valenti, L., Lampertico, P., Facchetti, F., Motta, B. M., D'Ambrosio, R., Romagnoli, S., Dongiovanni, P., Donati, B., Fargion, S. & Colombo, M., Oct 2013, In : Hepatology. 58, 4, p. 1245-1252 8 p.

Research output: Contribution to journalArticle

Phospholipases
Chronic Hepatitis B
Fatty Liver
Odds Ratio
Confidence Intervals
hepatoma
Polymorphism
Hepatocellular Carcinoma
genetic polymorphism
Liver

Randomised study comparing 48 and 96 weeks peginterferon α-2a therapy in genotype D HBeAg-negative chronic hepatitis B

Lampertico, P., Viganò, M., Di Costanzo, G. G., Sagnelli, E., Fasano, M., Di Marco, V., Boninsegna, S., Farci, P., Fargion, S., Giuberti, T., Iannacone, C., Regep, L., Massetto, B., Facchetti, F. & Colombo, M., Feb 2013, In : Gut. 62, 2, p. 290-298 9 p.

Research output: Contribution to journalArticle

Hepatitis B e Antigens
Chronic Hepatitis B
Genotype
Hepatitis B virus
Lamivudine
2011

Long-term add-on therapy with adefovir in lamivudine-resistant kidney graft recipients with chronic hepatitis B

Lampertico, P., Vigan, M., Facchetti, F., Invernizzi, F., Aroldi, A., Lunghi, G., Messa, P. G. & Colombo, M., Jun 2011, In : Nephrology Dialysis Transplantation. 26, 6, p. 2037-2041 5 p.

Research output: Contribution to journalArticle

Lamivudine
Chronic Hepatitis B
Transplants
Kidney
Hepatitis B virus

Risk of hepatitis B surface antigen seroreversion after allogeneic hematopoietic SCT

Viganò, M., Vener, C., Lampertico, P., Annaloro, C., Pichoud, C., Zoulim, F., Facchetti, F., Poli, F., Scalamogna, M., Deliliers, G. L. & Colombo, M., Jan 2011, In : Bone Marrow Transplantation. 46, 1, p. 125-131 7 p.

Research output: Contribution to journalArticle

Hepatitis B Surface Antigens
Hepatitis B virus
Hepatitis B Core Antigens
Hepatitis B Antibodies
Hepatitis B e Antigens
2008
Lamivudine
Hepatitis B
Chronic Hepatitis B
adefovir
DNA
2007

Effect of a caloric restriction regimen on the angiogenic capacity of aorta and on the expression of endothelin-1 during ageing

Facchetti, F., Monzani, E., Cavallini, G., Bergamini, E. & La Porta, C. A. M., Jul 2007, In : Experimental Gerontology. 42, 7, p. 662-667 6 p.

Research output: Contribution to journalArticle

Caloric Restriction
Endothelin-1
Aorta
Aging of materials
Rats

Melanoma contains CD133 and ABCG2 positive cells with enhanced tumourigenic potential

Monzani, E., Facchetti, F., Galmozzi, E., Corsini, E., Benetti, A., Cavazzin, C., Gritti, A., Piccinini, A., Porro, D., Santinami, M., Invernici, G., Parati, E., Alessandri, G. & La Porta, C. A. M., Mar 2007, In : European Journal of Cancer. 43, 5, p. 935-946 12 p.

Research output: Contribution to journalArticle

Melanoma
Cell Line
Biopsy
Heterografts
Neoplasms

New perspectives in the treatment of Melanoma: Anti-angiogenic and anti-lymphangiogenic strategies

Facchetti, F., Monzani, E. & La Porta, C. A. M., Jan 2007, In : Recent Patents on Anti-Cancer Drug Discovery. 2, 1, p. 73-78 6 p.

Research output: Contribution to journalArticle

Melanoma
Lymphangiogenesis
Therapeutics
Skin
Lymphatic Vessels
2006

BRAF V599E mutation occurs in Spitz and Reed naevi [24]

La Porta, C. A. M., Cardano, R., Facchetti, F., Presicce, P., Rao, S., Privitera, E., Clemente, C. & Mihm, M. C., Oct 2006, In : Journal of the European Academy of Dermatology and Venereology. 20, 9, p. 1164-1165 2 p.

Research output: Contribution to journalArticle

Cancer stem cells and therapeutic perspectives

Galmozzi, E., Facchetti, F. & La Porta, C. A. M., Mar 2006, In : Current Medicinal Chemistry. 13, 6, p. 603-607 5 p.

Research output: Contribution to journalArticle

Neoplastic Stem Cells
Stem cells
Stem Cells
Epigenomics
Neoplasms

Unique expression and localization of aquaporin- 4 and aquaporin-9 in murine and human neural stem cells and in their glial progeny

Cavazzin, C., Ferrari, D., Facchetti, F., Russignan, A., Vescovi, A. L., La Porta, C. A. M. & Gritti, A., Jan 15 2006, In : GLIA. 53, 2, p. 167-181 15 p.

Research output: Contribution to journalArticle

Aquaporin 4
Aquaporins
Neural Stem Cells
Neuroglia
Lateral Ventricles
2004

Modulation of pro- and anti-apoptotic factors in human melanoma cells exposed to histone deacetylase inhibitors

Facchetti, F., Previdi, S., Ballarini, M., Minucci, S., Perego, P. & Porta, C. A. M. L., Sep 2004, In : Apoptosis. 9, 5, p. 573-582 10 p.

Research output: Contribution to journalArticle

Histone Deacetylase Inhibitors
trichostatin A
Melanoma
Modulation
Cells
2001

Mutations in the thrombomodulin and endothelial protein C receptor genes in women with late fetal loss

Franchi, F., Biguzzi, E., Cetin, I., Facchetti, F., Radaelli, T., Bozzo, M., Pardi, G. & Faioni, E. M., 2001, In : British Journal of Haematology. 114, 3, p. 641-646 6 p.

Research output: Contribution to journalArticle

Thrombomodulin
Protein C
Mutation
Genes
Placental Insufficiency