If you made any changes in Pure these will be visible here soon.

Fingerprint Dive into the research topics where Francesca Cottino is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 23 Similar Profiles
Colorectal Neoplasms Medicine & Life Sciences
Epidermal Growth Factor Receptor Medicine & Life Sciences
Mitogen-Activated Protein Kinase Kinases Medicine & Life Sciences
erbB-2 Genes Medicine & Life Sciences
Therapeutics Medicine & Life Sciences
Somatomedins Medicine & Life Sciences
Colonic Neoplasms Medicine & Life Sciences
Lung Neoplasms Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Research Output 2014 2019

Combined blockade of MEK and PI3KCA as an effective antitumor strategy in HER2 gene amplified human colorectal cancer models

Belli, V., Matrone, N., Napolitano, S., Migliardi, G., Cottino, F., Bertotti, A., Trusolino, L., Martinelli, E., Morgillo, F., Ciardiello, D., De Falco, V., Giunta, E. F., Bracale, U., Ciardiello, F. & Troiani, T., Jun 4 2019, In : Journal of experimental & clinical cancer research : CR. 38, 1, p. 236

Research output: Contribution to journalArticle

erbB-2 Genes
Mitogen-Activated Protein Kinase Kinases
Colorectal Neoplasms
Epidermal Growth Factor Receptor
Therapeutics

HER2 activating mutations are targets for colorectal cancer treatment

Kavuri, S. M., Jain, N., Galimi, F., Cottino, F., Leto, S. M., Migliardi, G., Searleman, A. C., Shen, W., Monsey, J., Trusolino, L., Jacobs, S. A., Bertotti, A. & Bose, R., Aug 1 2015, In : Cancer Discovery. 5, 8, p. 832-841 10 p.

Research output: Contribution to journalArticle

Colorectal Neoplasms
Mutation
Therapeutics
Protein-Tyrosine Kinases
erbB-2 Genes
Somatomedins
Epidermal Growth Factor Receptor
Colorectal Neoplasms
Therapeutics
Tumor Biomarkers

The genomic landscape of response to EGFR blockade in colorectal cancer

Bertotti, A., Papp, E., Jones, S., Adleff, V., Anagnostou, V., Lupo, B., Sausen, M., Phallen, J., Hruban, C. A., Tokheim, C., Niknafs, N., Nesselbush, M., Lytle, K., Sassi, F., Cottino, F., Migliardi, G., Zanella, E. R., Ribero, D., Russolillo, N., Mellano, A. & 15 others, Muratore, A., Paraluppi, G., Salizzoni, M., Marsoni, S., Kragh, M., Lantto, J., Cassingena, A., Li, Q. K., Karchin, R., Scharpf, R., Sartore-Bianchi, A., Siena, S., Diaz, L. A., Trusolino, L. & Velculescu, V. E., Oct 8 2015, In : Nature. 526, 7572, p. 263-267 5 p.

Research output: Contribution to journalArticle

Epidermal Growth Factor Receptor
Colorectal Neoplasms
Neoplasms
Therapeutics
Transplants

Intrinsic resistance to MEK inhibition in kras mutant lung and colon cancer through transcriptional induction of ERBB3

Sun, C., Hobor, S., Bertotti, A., Zecchin, D., Huang, S., Galimi, F., Cottino, F., Prahallad, A., Grernrum, W., Tzani, A., Schlicker, A., Wessels, L. F. A., Smit, E. F., Thunnissen, E., Halonen, P., Lieftink, C., Beijersbergen, R. L., DiNicolantonio, F., Bardelli, A., Trusolino, L. & 1 others, Bernards, R., Oct 4 2014, In : Cell Reports. 7, 1, p. 86-93 8 p.

Research output: Contribution to journalArticle

Mitogen-Activated Protein Kinase Kinases
Colonic Neoplasms
Lung Neoplasms
Phosphorylation
Receptor Protein-Tyrosine Kinases