20162020

Research output per year

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Research Output

2020

Biological and clinical implications of BIRC3 mutations in chronic lymphocytic leukemia

Diop, F., Moia, R., Favini, C., Spaccarotella, E., De Paoli, L., Bruscaggin, A., Spina, V., Terzi-Di-Bergamo, L., Arruga, F., Tarantelli, C., Deambrogi, C., Rasi, S., Adhinaveni, R., Patriarca, A., Favini, S., Sagiraju, S., Jabangwe, C., Kodipad, A. A., Peroni, D., Mauro, F. R. & 30 others, Del Giudice, I., Forconi, F., Cortelezzi, A., Zaja, F., Bomben, R., Rossi, F. M., Visco, C., Chiarenza, A., Rigolin, G. M., Marasca, R., Coscia, M., Perbellini, O., Tedeschi, A., Laurenti, L., Motta, M., Donaldson, D., Weir, P., Mills, K., Thornton, P., Lawless, S., Bertoni, F., Poeta, G. D., Cuneo, A., Follenzi, A., Gattei, V., Boldorini, R. L., Catherwood, M., Deaglio, S., Foà, R. & Rossi, D., Jan 31 2020, In : Haematologica. 105, 2, p. 448-456 9 p.

Research output: Contribution to journalArticle

Open Access

Comparison of Hodgkin’s lymphoma in children and adolescents. A twenty year experience with MH’96 and LH2004 AIEOP (Italian association of pediatric hematology and oncology) protocols

Burnelli, R., Fiumana, G., Rondelli, R., Pillon, M., Sala, A., Garaventa, A., D'amore, E. S. G., Sabattini, E., Buffardi, S., Bianchi, M., Vinti, L., Zecca, M., Muggeo, P., Provenzi, M., Farruggia, P., Rossi, F., D'amico, S., Facchini, E., Bernasconi, S., De Santis, R. & 15 others, Casini, T., Porta, F., D'alba, I., Mura, R., Verzegnassi, F., Sau, A., Cesaro, S., Perruccio, K., Cellini, M., Bertolini, P., Sperlì, D., Pericoli, R., Galimberti, D., Civino, A. & Mascarin, M., Jun 2020, In : Cancers. 12, 6, p. 1-20 20 p., 1620.

Research output: Contribution to journalArticle

Open Access

Survival risk score for real-life relapsed/refractory chronic lymphocytic leukemia patients receiving ibrutinib. A campus CLL study

Gentile, M., Morabito, F., Del Poeta, G., Mauro, F. R., Reda, G., Sportoletti, P., Laurenti, L., Coscia, M., Herishanu, Y., Recchia, A. G., Varettoni, M., Murru, R., Chiarenza, A., Condoluci, A., Moia, R., Pietrasanta, D., Loseto, G., Consoli, U., Scortechini, I., Rossi, F. M. & 19 others, Zucchetto, A., Fraticelli, V., Vigna, E., Botta, C., Tripepi, G., Arrigo, G. D., Rago, A., Angeletti, I., Biagi, A., Del Giudice, I., Bomben, R., Rigolin, G. M., Rossi, D., Di Raimondo, F., Gaidano, G., Polliack, A., Cuneo, A., Foà, R. & Gattei, V., Jan 1 2020, (Accepted/In press) In : Leukemia.

Research output: Contribution to journalArticle

2019

A B-cell receptor-related gene signature predicts response to ibrutinib treatment in mantle cell lymphoma cell lines

D'Agaro, T., Zucchetto, A., Vit, F., Bittolo, T., Tissino, E., Rossi, F. M., Degan, M., Zaja, F., Bulian, P., Bo, M. D., Ferrero, S., Ladetto, M., Zamò, A., Gattei, V. & Bomben, R., Aug 31 2019, In : Haematologica. 104, 9, p. E410-E414 4 p.

Research output: Contribution to journalLetter

Open Access

A B-cell receptor-related gene signature predicts response to ibrutinib treatment in mantle cell lymphoma cell lines

D'Agaro, T., Zucchetto, A., Vit, F., Bittolo, T., Tissino, E., Rossi, F. M., Degan, M., Zaja, F., Bulian, P., Bo, M. D., Ferrero, S., Ladetto, M., Zamò, A., Gattei, V. & Bomben, R., Aug 31 2019, In : Haematologica. 104, 9, p. E410-E414

Research output: Contribution to journalLetter

Open Access

A laboratory-based scoring system predicts early treatment in Rai 0 chronic lymphocytic leukemia

Cohen, J. A., Rossi, F. M., Zucchetto, A., Bomben, R., Terzi-di-Bergamo, L., Rabe, K. G., Degan, M., Steffan, A., Polesel, J., Santinelli, E., Innocenti, I., Cutrona, G., D' Arena, G., Pozzato, G., Zaja, F., Chiarenza, A., Rossi, D., Di Raimondo, F., Laurenti, L., Gentile, M. & 9 others, Morabito, F., Neri, A., Ferrarini, M., Fegan, C. D., Pepper, C. J., Del Poeta, G., Parikh, S. A., Kay, N. E. & Gattei, V., Oct 3 2019, In : Haematologica.

Research output: Contribution to journalArticle

A laboratory-based scoring system predicts early treatment in Rai 0 chronic lymphocytic leukemia

Cohen, J. A., Rossi, F. M., Zucchetto, A., Bomben, R., Terzi-di-Bergamo, L., Rabe, K. G., Degan, M., Steffan, A., Polesel, J., Santinelli, E., Innocenti, I., Cutrona, G., D' Arena, G., Pozzato, G., Zaja, F., Chiarenza, A., Rossi, D., Di Raimondo, F., Laurenti, L., Gentile, M. & 9 others, Morabito, F., Neri, A., Ferrarini, M., Fegan, C. D., Pepper, C. J., Del Poeta, G., Parikh, S. A., Kay, N. E. & Gattei, V., Oct 3 2019, In : Haematologica. p. haematol.2019.228171

Research output: Contribution to journalArticle

A laboratory-based scoring system predicts early treatment in Rai 0 chronic lymphocytic leukemia.

Cohen, J. A., Rossi, F. M., Zucchetto, A., Bomben, R., Terzi-di-Bergamo, L., Rabe, K. G., Degan, M., Steffan, A., Polesel, J., Santinelli, E., Innocenti, I., Cutrona, G., D' Arena, G., Pozzato, G., Zaja, F., Chiarenza, A., Rossi, D., Di Raimondo, F., Laurenti, L., Gentile, M. & 9 others, Morabito, F., Neri, A., Ferrarini, M., Fegan, C. D., Pepper, C. J., Del Poeta, G., Parikh, S. A., Kay, N. E. & Gattei, V., 2019, In : Haematologica.

Research output: Contribution to journalArticle

A national multicenter study on 1072 DCIS patients treated with breast-conserving surgery and whole breast radiotherapy (COBCG-01 study)

Clinical Oncology Breast Cancer Group (COBCG) Investigators, Feb 2019, In : Radiotherapy and Oncology. 131, p. 208-214 7 p.

Research output: Contribution to journalArticle

Does deep inspiration breath hold reduce plan complexity? Multicentric experience of left breast cancer radiotherapy with volumetric modulated arc therapy

Russo, S., Esposito, M., Hernandez, V., Saez, J., Rossi, F., Paoletti, L., Pini, S., Bastiani, P., Reggiori, G., Nicolini, G., Vanetti, E., Tomatis, S., Scorsetti, M. & Mancosu, P., Mar 2019, In : Physica Medica. 59, p. 79-85 7 p.

Research output: Contribution to journalArticle

KRAS, NRAS, and BRAF mutations are highly enriched in trisomy 12 chronic lymphocytic leukemia and are associated with shorter treatment-free survival

Vendramini, E., Bomben, R., Pozzo, F., Benedetti, D., Bittolo, T., Rossi, F. M., Dal Bo, M., Rabe, K. G., Pozzato, G., Zaja, F., Chiarenza, A., Di Raimondo, F., Braggio, E., Parikh, S. A., Kay, N. E., Shanafelt, T. D., Del Poeta, G., Gattei, V. & Zucchetto, A., Aug 1 2019, In : Leukemia. 33, 8, p. 2111-2115 5 p.

Research output: Contribution to journalLetter

Open Access
2018

A national multicenter study on 1072 DCIS patients treated with breast-conserving surgery and whole breast radiotherapy (COBCG-01 study)

Clinical Oncology Breast Cancer Group (COBCG) Investigators, Jan 1 2018, (Accepted/In press) In : Radiotherapy and Oncology.

Research output: Contribution to journalArticle

Biallelic BIRC3 inactivation in chronic lymphocytic leukaemia patients with 11q deletion identifies a subgroup with very aggressive disease

Raponi, S., Del Giudice, I., Ilari, C., Cafforio, L., Messina, M., Cappelli, L. V., Bonina, S., Piciocchi, A., Marinelli, M., Peragine, N., Mariglia, P., Mauro, F. R., Rigolin, G. M., Rossi, F. M., Bomben, R., Dal Bo, M., Del Poeta, G., Diop, F., Favini, C., Rossi, D. & 5 others, Gaidano, G., Cuneo, A., Gattei, V., Guarini, A. & Foá, R., Jan 1 2018, In : British Journal of Haematology.

Research output: Contribution to journalArticle

Classical pediatric Hodgkin lymphoma in very young patients: the Italian experience

Farruggia, P., Puccio, G., Locatelli, F., Vetro, M., Pillon, M., Trizzino, A., Sala, A., Buffardi, S., Garaventa, A., Rossi, F., Bianchi, M., Zecca, M., Pession, A., Favre, C., D'Amico, S., Provenzi, M., Zanazzo, G. A., Sau, A., Santoro, N., Mura, R. & 4 others, Elia, C., Casini, T., Mascarin, M. & Burnelli, R., Oct 10 2018, In : Leukemia and Lymphoma. p. 1-7 7 p.

Research output: Contribution to journalArticle

Functional and clinical relevance of VLA-4 (CD49d/CD29) in ibrutinib-treated chronic lymphocytic leukemia

Tissino, E., Benedetti, D., Herman, S. E. M., ten Hacken, E., Ahn, I. E., Chaffee, K. G., Rossi, F. M., Bo, M. D., Bulian, P., Bomben, R., Bayer, E., Härzschel, A., Gutjahr, J. C., Postorino, M., Santinelli, E., Ayed, A., Zaja, F., Chiarenza, A., Pozzato, G., Chigaev, A. & 9 others, Sklar, L. A., Burger, J. A., Ferrajoli, A., Shanafelt, T. D., Wiestner, A., Del Poeta, G., Hartmann, T. N., Gattei, V. & Zucchetto, A., Feb 1 2018, In : Journal of Experimental Medicine. 215, 2, p. 681-697 17 p.

Research output: Contribution to journalArticle

Functional assessment tools in children with Pompe disease: A pilot comparative study to identify suitable outcome measures for the standard of care

Ricci, F., Brusa, C., Rossi, F., Rolle, E., Placentino, V., Berardinelli, A., Pagliardini, V., Porta, F., Spada, M. & Mongini, T., Nov 1 2018, In : European Journal of Paediatric Neurology. 22, 6, p. 1103-1109 7 p.

Research output: Contribution to journalArticle

Improved GMP compliant approach to manipulate lipoaspirates, to cryopreserve stromal vascular fraction, and to expand adipose stem cells in xeno-free media

Agostini, F., Rossi, F. M., Aldinucci, D., Battiston, M., Lombardi, E., Zanolin, S., Massarut, S., Parodi, P. C., Da Ponte, A., Tessitori, G., Pivetta, B., Durante, C. & Mazzucato, M., May 11 2018, In : Stem Cell Research and Therapy. 9, 1, 130.

Research output: Contribution to journalArticle

NOTCH1 mutations are associated with high CD49d expression in chronic lymphocytic leukemia: Link between the NOTCH1 and the NF-κ B pathways

Benedetti, D., Tissino, E., Pozzo, F., Bittolo, T., Caldana, C., Perini, C., Martorelli, D., Bravin, V., D'Agaro, T., Rossi, F. M., Bomben, R., Santinelli, E., Zaja, F., Pozzato, G., Chiarenza, A., Di Raimondo, F., Del Poeta, G., Rossi, D., Gaidano, G., Dal Bo, M. & 2 others, Gattei, V. & Zucchetto, A., Mar 1 2018, In : Leukemia. 32, 3, p. 654-662 9 p.

Research output: Contribution to journalArticle

PQR309 is a novel dual PI3K/mTOR inhibitor with preclinical antitumor activity in lymphomas as a single agent and in combination therapy

Tarantelli, C., Gaudio, E., Arribas, A. J., Kwee, I., Hillmann, P., Rinaldi, A., Cascione, L., Spriano, F., Bernasconi, E., Guidetti, F., Carrassa, L., Pittau, R. B., Beaufils, F., Ritschard, R., Rageot, D., Sele, A., Dossena, B., Rossi, F. M., Zucchetto, A., Taborelli, M. & 11 others, Gattei, V., Rossi, D., Stathis, A., Stussi, G., Broggini, M., Wymann, M. P., Wicki, A., Zucca, E., Cmiljanovic, V., Fabbro, D. & Bertoni, F., Jan 1 2018, In : Clinical Cancer Research. 24, 1, p. 120-129 10 p.

Research output: Contribution to journalArticle

2017

Mutational status of IGHV is the most reliable prognostic marker in trisomy 12 chronic lymphocytic leukemia

Bulian, P., Bomben, R., Dal Bo, M., Zucchetto, A., Rossi, F. M., Degan, M., Pozzo, F., Bittolo, T., Bravin, V., D’Agaro, T., Cerri, M., Chiarenza, A., Chaffee, K. G., Condoluci, A., D’Arena, G., Spina, M., Zaja, F., Pozzato, G., Di Raimondo, F., Rossi, D. & 4 others, Del Poeta, G., Gaidano, G., Shanafelt, T. D. & Gattei, V., Oct 27 2017, In : Haematologica. 102, 11, p. e443-e446 3 p.

Research output: Contribution to journalLetter

Mutational status of IGHV is the most reliable prognostic marker in trisomy 12 chronic lymphocytic leukemia

Bulian, P., Bomben, R., Bo, M. D., Zucchetto, A., Rossi, F. M., Degan, M., Pozzo, F., Bittolo, T., Bravin, V., D'Agaro, T., Cerri, M., Chiarenza, A., Chaffee, K. G., Condoluci, A., D'Arena, G., Spina, M., Zaja, F., Pozzato, G., Di Raimondo, F., Rossi, D. & 4 others, Poeta, G. D., Gaidano, G., Shanafelt, T. D. & Gattei, V., Nov 2017, In : Haematologica. 102, 11, p. e443-e446

Research output: Contribution to journalArticle

Mutational status of IGHV is the most reliable prognostic marker in trisomy 12 chronic lymphocytic leukemia

Bulian, P., Bomben, R., Dal Bo, M., Zucchetto, A., Rossi, F. M., Degan, M., Pozzo, F., Bittolo, T., Bravin, V., D’Agaro, T., Cerri, M., Chiarenza, A., Chaffee, K. G., Condoluci, A., D’Arena, G., Spina, M., Zaja, F., Pozzato, G., Di Raimondo, F., Rossi, D. & 4 others, Del Poeta, G., Gaidano, G., Shanafelt, T. D. & Gattei, V., Oct 27 2017, In : Haematologica. 102, 11, p. e443-e446

Research output: Contribution to journalLetter

Mutations in the 3′ untranslated region of NOTCH1 are associated with low CD20 expression levels in chronic lymphocytic leukemia

Bittolo, T., Pozzo, F., Bomben, R., D’Agaro, T., Bravin, V., Bulian, P., Rossi, F. M., Zucchetto, A., Degan, M., Macor, P., D’Arena, G., Chiarenza, A., Zaja, F., Pozzato, G., Di Raimondo, F., Rossi, D., Gaidano, G., Del Poeta, G., Gattei, V. & Dal Bo, M., 2017, In : Haematologica. 102, 8, p. e305-e309

Research output: Contribution to journalArticle

Mutations in the 3′ untranslated region of NOTCH1 are associated with low CD20 expression levels in chronic lymphocytic leukemia

Bittolo, T., Pozzo, F., Bomben, R., D’Agaro, T., Bravin, V., Bulian, P., Rossi, F. M., Zucchetto, A., Degan, M., Macor, P., D’Arena, G., Chiarenza, A., Zaja, F., Pozzato, G., Di Raimondo, F., Rossi, D., Gaidano, G., Del Poeta, G., Gattei, V. & Dal Bo, M., Jul 31 2017, In : Haematologica. 102, 8, p. e305-e309

Research output: Contribution to journalLetter

NOTCH1-mutated chronic lymphocytic leukemia cells are characterized by a MYC-related overexpression of nucleophosmin 1 and ribosome-associated components

Pozzo, F., Bittolo, T., Vendramini, E., Bomben, R., Bulian, P., Rossi, F. M., Zucchetto, A., Tissino, E., Degan, M., D’Arena, G., Di Raimondo, F., Zaja, F., Pozzato, G., Rossi, D., Gaidano, G., Del Poeta, G., Gattei, V. & Dal Bo, M., 2017, In : Leukemia. 31, 11, p. 2407-2415 9 p.

Research output: Contribution to journalArticle

NOTCH1 mutational status in chronic lymphocytic leukaemia: clinical relevance of subclonal mutations and mutation types

D'Agaro, T., Bittolo, T., Bravin, V., Dal Bo, M., Pozzo, F., Bulian, P., Rossi, F. M., Zucchetto, A., Degan, M., D'Arena, G., Chiarenza, A., Zaja, F., Pozzato, G., Di Raimondo, F., Rossi, D., Gaidano, G., Del Poeta, G., Gattei, V. & Bomben, R., Jul 12 2017, In : British Journal of Haematology.

Research output: Contribution to journalArticle

Pronounced structural and functional damage in early adult pediatric-onset multiple sclerosis with no or minimal clinical disability

Giorgio, A., Zhang, J., Stromillo, M. L., Rossi, F., Battaglini, M., Nichelli, L., Mortilla, M., Portaccio, E., Hakiki, B., Amato, M. P. & De Stefano, N., Nov 14 2017, In : Frontiers in Neurology. 8, NOV, 608.

Research output: Contribution to journalArticle

2016

CD49d prevails over the novel recurrent mutations as independent prognosticator of overall survival in chronic lymphocytic leukemia

Dal Bo, M., Bulian, P., Bomben, R., Zucchetto, A., Rossi, F. M., Pozzo, F., Tissino, E., Benedetti, D., Bittolo, T., Nanni, P., Cattarossi, I., Zaina, E., Chivilò, H., Degan, M., Zaja, F., Pozzato, G., Chiarenza, A., Di Raimondo, F., Del Principe, M. I., Del Poeta, G. & 3 others, Rossi, D., Gaidano, G. & Gattei, V., May 20 2016, In : Leukemia. p. 2011 2018 p.

Research output: Contribution to journalArticle

Clinical significance of bax/bcl-2 ratio in chronic lymphocytic leukemia

Del Principe, M. I., Dal Bo, M., Bittolo, T., Buccisano, F., Rossi, F. M., Zucchetto, A., Rossi, D., Bomben, R., Maurillo, L., Cefalo, M., De Santis, G., Venditti, A., Gaidano, G., Amadori, S., de Fabritiis, P., Gattei, V. & Del Poeta, G., 2016, In : Haematologica. 101, 1, p. 77-85 9 p.

Research output: Contribution to journalArticle

Functional and clinical significance of the integrin alpha chain CD49d expression in chronic lymphocytic leukemia

Dal Bo, M., Tissino, E., Benedetti, D., Caldana, C., Bomben, R., del Poeta, G., Gaidano, G., Rossi, F. M., Bulian, P., Zucchetto, A. & Gattei, V., Oct 1 2016, In : Current Cancer Drug Targets. 16, 8, p. 659-668 10 p.

Research output: Contribution to journalReview article

NOTCH1 mutations associate with low CD20 level in chronic lymphocytic leukemia: Evidence for a NOTCH1 mutation-driven epigenetic dysregulation

Pozzo, F., Bittolo, T., Arruga, F., Bulian, P., MacOr, P., Tissino, E., Gizdic, B., Rossi, F. M., Bomben, R., Zucchetto, A., Benedetti, D., Degan, M., D'Arena, G., Chiarenza, A., Zaja, F., Pozzato, G., Rossi, D., Gaidano, G., Del Poeta, G., Deaglio, S. & 2 others, Gattei, V. & Dal Bo, M., Jan 1 2016, In : Leukemia. 30, 1, p. 182-189 8 p.

Research output: Contribution to journalArticle

NOTCH1 mutations associate with low CD20 level in chronic lymphocytic leukemia: Evidence for a NOTCH1 mutation-driven epigenetic dysregulation

Pozzo, F., Bittolo, T., Arruga, F., Bulian, P., MacOr, P., Tissino, E., Gizdic, B., Rossi, F. M., Bomben, R., Zucchetto, A., Benedetti, D., Degan, M., D'Arena, G., Chiarenza, A., Zaja, F., Pozzato, G., Rossi, D., Gaidano, G., Del Poeta, G., Deaglio, S. & 2 others, Gattei, V. & Dal Bo, M., Jan 1 2016, In : Leukemia. 30, 1, p. 182-189 8 p.

Research output: Contribution to journalArticle